European Archives of Oto-Rhino-Laryngology最新文献

{"title":"Impact of cochlear detailed morphology on insertion results and intracochlear trauma of a slim pre-curved electrode array: a micro-CT study.","authors":"Jiabao Mao, Linhan Huang, Zhangcai Chi, Min Chen, Wen Li, Shufeng Li","doi":"10.1007/s00405-024-09058-1","DOIUrl":"10.1007/s00405-024-09058-1","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the impact of detailed cochlear dimensions, assessed using micro-CT (µCT) imaging, on insertion outcomes and associated trauma with a new slim, precurved electrode array.</p><p><strong>Materials and methods: </strong>Eleven temporal bone specimens underwent implantation of a 22-electrode slim precurved array via the round window. High-resolution µCT scans post-implantation enabled visualization of cochlear structures and electrode positioning. Combination with subsequent scans taken after electrodes removal, we analyzed angular insertion depth (AID), insertion length, number of electrodes inserted, cochlear dimensions (specifically cochlear duct length (CDL), basal turn diameter, scala tympani dimension), and intracochlear trauma of fine structures. Statistical analyses were performed to correlate cochlear detailed dimensions and morphology with insertion outcomes and trauma.</p><p><strong>Results: </strong>The mean AID was 351.82°, and the mean insertion length was 21.07 mm. CDL showed positive correlations with AID and insertion length. Basal turn diameter (value B) positively correlated with AID and insertion length, unlike value A. Middle-basal turn (M/B) relationships (angle and height) significantly influenced insertion depth. The cochleae with smaller M/B heights and specific angles were more susceptible to insertion trauma. Larger basal turn diameters correlated with increased trauma and electrode translocation into the scala vestibuli.</p><p><strong>Conclusion: </strong>This study highlights the importance of precise cochlear measurements in predicting and optimizing cochlear implant outcomes. Specific cochlear dimensions and anatomical shapes were identified as critical factors affecting insertion depth, trauma risk, and electrode positioning. Utilizing micro-CT provided detailed insights into cochlear anatomy and insertion outcomes, offering valuable data for advancing cochlear implant technology and surgical practices.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"1769-1781"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of optimal sedation depth in sleep endoscopy with bispectrometry and simultaneous polysomnography.","authors":"Öznur Gündüz, Kürşat Murat Özcan, Fatma Cemre Sazak Kundi, Ezgi Erkılıç, Selma Fırat","doi":"10.1007/s00405-024-09194-8","DOIUrl":"10.1007/s00405-024-09194-8","url":null,"abstract":"<p><strong>Objective: </strong>In this study, we aimed to evaluate the localization and configuration of vibration and obstruction in drug-induced sleep endoscopy(DISE) in obstructive sleep apnea patients and to investigate the optimal sedation depth.</p><p><strong>Materials and methods: </strong>The study was conducted prospectively with 42 patients. After achieving sedation with intravenous anesthetic agents, simultaneous monitoring of the patient's bispectrometry (BIS), DISE and sleep testing with a type 2 polysomnography device were performed. DISE was performed using fentanyl and midazolam, followed by propofol administered with manually controlled infusion method. The recorded data were evaluated and subjected to statistical comparisons.</p><p><strong>Results: </strong>It was observed that as BIS values decreased, the frequency of decreased respiratory effort and desaturation increased. Central apneas were observed with BIS values below 65 and were found to increase with deeper sedation, while with BIS values above 70, all respiratory events were obstructive apneas, with retro-palatal obstruction being the most common. It was noted that vibration occurred in over 90% of patients within the BIS range of 60-70. It was decided that the optimal sedation depth for evaluating vibration and obstruction in sleep endoscopy was within the BIS range of 60-75.</p><p><strong>Conclusion: </strong>According to the results of our study, as sedation depth increases, the frequency of central apnea and desaturation increases. In our study, the sedation depth within the BIS 60-75 range was found to be the most suitable range for evaluating obstructive apnea and snoring.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"2141-2148"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the role of miRNA in laryngeal squamous cell carcinoma progression: a retrospective study.","authors":"Nejmiye Akkuş, Elif Kaya Çelik, Suleyman Ozdemir, Emrah Sapmaz","doi":"10.1007/s00405-025-09306-y","DOIUrl":"https://doi.org/10.1007/s00405-025-09306-y","url":null,"abstract":"<p><strong>Objective: </strong>MicroRNAs (miRNAs) have emerged as promising biomarkers for diagnosis and prognosis in laryngeal squamous cell carcinoma (LSCC). This study investigates the expression patterns of specific cancer-associated miRNAs in early and advanced stage LSCC to evaluate their potential role in disease progression.</p><p><strong>Methods: </strong>The expression levels of miRNA-21, miRNA-802, miRNA-29 and miRNA-9 were analysed in formalin-fixed paraffin-embedded (FFPE) tissues from 44 LSCC patients (20 early stage, 24 advanced stage) using quantitative multiplex RT-PCR. Tissue samples were analysed retrospectively.</p><p><strong>Results: </strong>The expression level of hsa-miR-9a expression was significantly upregulated (5.2-fold) in advanced stage patients compared to the early stage group (p = 0.0088). Similarly, hsa-miR-802a showed significantly higher expression (9.2-fold) in advanced stage patients compared to early stage patients (p = 0.005). No significant differences in miRNA-21 and miRNA-29 expression levels were observed between the groups.</p><p><strong>Conclusion: </strong>As a result of the study, elevated miRNA levels in advanced stage patients can be used in targeted therapy and evaluated as a treatment option in LSCC patients.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Locally advanced maxillary sinus cancer fed from the internal carotid artery.","authors":"Tatsuhiko Yamada, Masashi Kuroki, Hirofumi Shibata, Shoma Nagata, Hiroshi Kawada, Hiroki Kato, Akira Ohkoshi, Ikuho Kojima, Ryota Iinuma, Hiroshi Okuda, Yukio Katori, Masayuki Matsuo, Takenori Ogawa","doi":"10.1007/s00405-025-09343-7","DOIUrl":"https://doi.org/10.1007/s00405-025-09343-7","url":null,"abstract":"<p><strong>Objective: </strong>Superselective intra-arterial infusion of cisplatin and concomitant radiation therapy (RADPLAT) is one of the effective treatments for advanced maxillary sinus cancer, and prospective trials have been conducted. However, treatment of cases with intraorbital infiltration or skull base infiltration that are fed from the internal carotid artery (ICA) may be problematic. In this study, we investigated the frequency, treatment, and prognosis of locally advanced maxillary sinus cancer fed from the ICA.</p><p><strong>Method: </strong>This study included patients with locally advanced maxillary sinus cancer (clinical T4a or T4b) who underwent RADPLAT only via external carotid artery from January 2008 to January 2024.</p><p><strong>Result: </strong>Nineteen of 44 cases were fed from the ICA (43.2%). Three-year overall survival (OS), three-year progression-free survival (PFS), and three-year local control rate (LCR) of all cases were 69.8%, 47.5%, and 61.8%, respectively. The three-year OS, PFS and LCR were equivalent between cases with or without feeding from the ICA.</p><p><strong>Conclusion: </strong>This study revealed the frequency and prognosis of locally advanced maxillary sinus cancer fed from the ICA. The prognosis was equivalent between cases with or without feeding from the ICA; therefore, it would be considered important to determine the tumor volume for each feeding blood vessel and assess the areas of dual perfusion.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of home discharge rates following total (pharyngo-)laryngectomy after implementation of a city-hospital network.","authors":"Ismaël Ouzzine, Stéphane Gargula, Ralph Haddad, Stéphane Fabriès, Laure Santini, Pauline Paris, Alexia Mattei, Justin Michel, Nicolas Fakhry","doi":"10.1007/s00405-025-09354-4","DOIUrl":"https://doi.org/10.1007/s00405-025-09354-4","url":null,"abstract":"<p><strong>Introduction: </strong>In 2017, an innovative partnership was established between the ENT department of La Conception Hospital in Marseille and a city-hospital network (ILHUP) to facilitate early discharge after total laryngectomy (TL) and total pharyngo-laryngectomy (TPL). The main objective was to compare the home discharge rate versus transfer to a rehabilitation facility before and after implementation of this partnership.</p><p><strong>Methods: </strong>This single-center retrospective study included 205 patients who underwent TL/TPL between January 2012 and December 2023, divided into two groups: group 1 (n = 93) and group 2 (n = 112) before and after implementation of the city-hospital network.</p><p><strong>Results: </strong>The home discharge rate in Group 2 was significantly higher than in Group 1 (55.4% vs. 40.9%, p = 0.039). Within group 2, mean length of hospital stay (23.8 vs. 26.12 days, p = 0.295) and two-month readmission rate (4.8% vs. 10%, p = 0.321) were similar between patients discharged home and those transferred to rehabilitation facilities. Multivariate analysis showed that implementation of the city-hospital network partnership was the only factor independently associated with an increased home discharge rate (p = 0.018).</p><p><strong>Conclusion: </strong>Implementation of a partnership with a city-hospital network significantly increased the home discharge rate after total (pharyngo-) laryngectomy without compromising patient safety.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing surgical strategies for frontal sinus osteomas: a proposal for classification.","authors":"Carmine Prizio, Andrea Achena, Andrea Lorenzi, Carola Micolitti, Remo Accorona, Francesco Pilolli, Antonino Maniaci, Niccolò Mevio, Alberto Giulio Dragonetti","doi":"10.1007/s00405-025-09331-x","DOIUrl":"https://doi.org/10.1007/s00405-025-09331-x","url":null,"abstract":"<p><strong>Purpose: </strong>Frontal sinus osteomas are benign tumors that often require surgical resection due to their proximity to critical anatomical structures. The surgical approach can vary significantly depending on the size, location, and extent of involvement of these structures. Currently, no universally accepted classification system exists to guide the surgical management of frontal sinus osteomas. This study proposes a classification system based on these factors, with the objective of providing a standardized approach for selecting the most appropriate surgical techniques.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on all patients who underwent surgical resection of frontal sinus osteomas at a single institution from 2012 to 2024. Osteomas were categorized into three grades (I, II, and III) based on size, location, and anatomical features. Surgical outcomes were analyzed in relation to the osteoma classification.</p><p><strong>Results: </strong>Fifty-two patients were included in the study. Of these, 41 (78.8%) patients were treated using an endoscopic approach, 7 (13.5%) with an open approach, and 4 (7.7%) with a combined approach. According to the classification, 25 (48.1%) osteomas were categorized as grade I, 14 (26.9%) as grade II, 13 (25.0%) as grade III. Grade I osteomas were predominantly managed with endoscopic techniques, while grade II osteomas required extended endoscopic approaches. Grade III necessitated open or combined approaches.</p><p><strong>Conclusion: </strong>This classification system provides a structured approach for determining the optimal surgical method for frontal sinus osteomas, aiming to reduce variability in treatment and improve patient outcomes.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of postoperative sucralfate in adults following tonsillectomy and sleep surgery: a systematic review.","authors":"Lauren R McCray, Erin E Briggs, Jaimin J Patel, Shaun A Nguyen, Noah Parker","doi":"10.1007/s00405-025-09311-1","DOIUrl":"https://doi.org/10.1007/s00405-025-09311-1","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the efficacy of topical sucralfate on postoperative recovery following oropharyngeal surgery in adults using pain scales, analgesic use, and various self-reported measures.</p><p><strong>Methods: </strong>CINAHL, Cochrane Library, PubMed, and SCOPUS databases were searched from inception through July 3, 2024. Randomized controlled trials related to topical sucralfate following oropharyngeal surgery in patients at least 18 years old were included. Study protocols for clinical trials, abstracts, and non-English language articles were excluded. Two authors extracted data, and disagreements were resolved with a third party if needed. Risk of bias was assessed according to Risk of Bias 2 (RoB 2) tool. Results of included studies and a narrative summary of our findings are presented through descriptive statistics (frequency (%) for categorical variables and mean (range) for continuous variables).</p><p><strong>Results: </strong>Four studies (n = 185) pertaining to topical sucralfate and post-operative outcomes in an adult population were included. The sucralfate group had a mean age of 40.08 vs. 37.50 for the control group. The sucralfate group had a significantly higher reduction in pain scores than the control group. The sucralfate group also had statistically significant improvements in otalgia, strength, diet tolerance, and reduction in analgesic use compared to the control group in two of the four studies.</p><p><strong>Conclusions: </strong>Oropharyngeal surgery is commonly performed in adults despite having a morbid recovery process. The literature shows promising results with the use of sucralfate in the reduction of post-operative pain in adults; however, further investigation is warranted given the limited scope of the literature.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary results of a new endoscopic underlay cartilage tympanoplasty with lateral malleolar flap.","authors":"Pinar Atabey, Burcu Vural Camalan, Hasan Demirel, Mehmet Beyhan Balur, Sumeyra Doluoglu","doi":"10.1007/s00405-025-09337-5","DOIUrl":"https://doi.org/10.1007/s00405-025-09337-5","url":null,"abstract":"<p><strong>Background: </strong>A new endoscopic tympanoplasty technique for large and medium-sized central perforations via a transcanal approach, without tympanomeatal flap elevation compared the preliminary postoperative graft success and hearing outcomes with other techniques in the literature.</p><p><strong>Methods: </strong>The study involved 75 patients aged 12 to 44 who underwent tympanoplasty with the lateral malleolar flap technique from 2014 to 2017. Pre-operative otoscopy recorded perforation sizes, and pure tone averages were calculated at 500, 1000, 2000, and 4000 Hz. The procedure was performed under general anesthesia via a transcanal approach using tragal cartilage, without tympanomeatal flap elevation. A control otoscopy was conducted six months post-operation to assess reperforation and graft position. Pure tone averages were measured, and pre-operative and post-operative audiological values were compared.</p><p><strong>Results: </strong>Post-operative six-month graft success rate was 94.6%. Reperforation was observed in one patient (1.3%), while another patient (1.3%) exhibited lateralization, and two patients (2.6%) demonstrated medialization. The pre-operative mean hearing level was recorded at 33.3 ± 7.0 dB, accompanied by an Air-Bone Gap (ABG) of 24.0 ± 6.6 dB. Post-operative measurements indicated an improvement in these values, with the mean hearing level decreasing to 18.0 ± 4.8 dB and the ABG reducing to 16.3 ± 5.3 dB (p < 0.05).</p><p><strong>Conclusion: </strong>The endoscopic underlay cartilage tympanoplasty with lateral malleolar flap is a safe technique that avoids elevating the tympanomeatal flap. It offers shorter operation time, easier postoperative dressing, and high graft success rates similar to other tympanoplasty techniques.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The challenge of diagnosing intracranial pressure elevations as an otolaryngologist.","authors":"Michelle S Klausner, Gerard J Gianoli, Patricia Johnson, Bulent Mamikoglu","doi":"10.1007/s00405-025-09333-9","DOIUrl":"https://doi.org/10.1007/s00405-025-09333-9","url":null,"abstract":"<p><strong>Purpose: </strong>This article addresses the complex clinical scenario where patients present to otolaryngologists with symptoms typically ascribed to chronic rhinosinusitis (CRS) or migraines which may in fact stem from elevations in intracranial pressure. We aim to clarify the diagnostic challenges and emphasize the importance of considering elevated intracranial pressure (eICP) as its symptoms overlap with both CRS and migraines.</p><p><strong>Methods: </strong>This narrative review synthesizes clinical experiences and literature to discuss the differential diagnoses involving CRS, facial pain/pressure, migraines, and eICP. Key discussion points include symptomatology of eICP and its management in otolaryngological practice.</p><p><strong>Results: </strong>Patients presenting with symptoms of CRS or migraine may exhibit overlapping signs that makes diagnosis challenging. Patients with symptoms of facial pain and pressure, or other findings such as ear fullness, muffled hearing, and tinnitus, that do not resolve with conventional topical intranasal therapies or migraine management should be worked up for eICP.</p><p><strong>Conclusion: </strong>The overlap in clinical presentations among patients with concern for CRS, migraines, and ICP elevations poses a diagnostic challenge. It is crucial for otolaryngologists and neurologists to collaborate closely to ensure accurate diagnoses and appropriate management. Enhanced awareness and understanding of the broader spectrum of symptoms associated with eICP can prevent misdiagnosis and promote better patient outcomes.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between peripheral blood basophils and chronic sinusitis with nasal polyps in different age groups.","authors":"Lingling Xu","doi":"10.1007/s00405-025-09351-7","DOIUrl":"https://doi.org/10.1007/s00405-025-09351-7","url":null,"abstract":"<p><strong>Purpose: </strong>Despite improved surgical and medical therapies, it remains a disease entity that is difficult to cure chronic rhinosinusitis with nasal polyps (CRSwNP), given a recently-reported incidence up to 4% of the population severely affects patients' quality of life. In this retrospective study, we attempted to assess the role of another important inflammatory cell, the blood basophil, in a large series of patients with CRSwNP (n = 316) across three different age groups.</p><p><strong>Methods: </strong>The investigation concerned 316 consecutive patients undergoing endoscopic sinus surgery (ESS) for CRSwNP. We divided these patients into three groups according to age, of which, 46 consecutive geriatric patients ( ≧ 61y), 243 consecutive young adult CRSwNP patients (19-60y), and 27 pediatric patients (≤ 18y) were enrolled.</p><p><strong>Results: </strong>Compared between groups, WBC and eosinophil counts in peripheral blood were not statistically different among the three groups, while blood basophil (p = 0.016), lymphocyte (p < 0.001), monocyte (p = 0.031) counts and LM scores (p = 0.025) were statistically different between groups, all of which were significantly different between pediatric and adult groups, pediatric and elderly groups. Spearman correlation analysis revealed blood basophil counts were positively correlated with blood eosinophils, leukocytes, lymphocytes, monocyte counts, and LM scores overall in the sample as a whole (p < 0.001).</p><p><strong>Conclusion: </strong>The heterogeneous role of blood basophils identified in different age sub-cohorts of CRSwNP supports the hypothesis that blood basophil count may reflect the severity of inflammation in CRSwNP patients. In addition, we should pay attention to the long-term follow-up of pediatric patients with CRSwNP.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}