Analysis of sensorineural hearing loss and its relation to Optical Coherence Tomography Angiography findings in Behcet's disease.

IF 2.2 3区 医学 Q2 OTORHINOLARYNGOLOGY
Maha S I Abdelrahman, Mohamed G A Saleh, Maha Abdelgaber A Aly, Shaimaa Salah
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引用次数: 0

Abstract

Objectives: We aimed to analyze auditory involvement in patients with Behcet's disease and its association with Optical Coherence Tomography Angiography findings and disease manifestations.

Methods: This study included 54 eyes and 68 ears of 34 adults with Behcet's disease in comparison to 30 eyes and 60 ears of healthy controls. Clinical, laboratory and ophthalmological evaluation including Optical Coherence Tomography Angiography was done. Audiological assessment included otoscopic examination, immitancemetry and pure tone and speech audiometry.

Results: Sensorineural hearing loss was observed in 32.35% of the studied cases. Behcet's disease patients showed significantly higher average hearing level and significant reduction of retinal vessel density compared to controls. Patients with sensorineural hearing loss demonstrated significantly lower central retinal capillary vessel density and higher neuro-Behcet's disease incidence in comparison to those without hearing loss (p-value = 0.039 and 0.024, respectively), which was confirmed by univariate regression analysis. After entering significant factors into the multivariate model, neuro-BD was identified as the most significant single predictor of sensorineural hearing loss in BD (p-value = 0.003).

Conclusions: The association between sensorineural hearing loss and central retinal vessel density reduction and neuro- Behcet's disease should be considered in Behcet's disease.

Abstract Image

白塞氏病感音神经性听力损失及其与光学相干断层血管造影表现的关系分析。
目的:我们旨在分析白塞病患者的听觉损害及其与光学相干断层扫描血管造影结果和疾病表现的关系。方法:本研究包括34名成年白塞氏病患者的54只眼睛和68只耳朵,与健康对照者的30只眼睛和60只耳朵进行比较。进行了包括光学相干断层扫描血管造影在内的临床、实验室和眼科评估。听力学评估包括耳镜检查、听力测试、纯音和语音听力测试。结果:32.35%的病例出现感音神经性听力损失。与对照组相比,白塞氏病患者的平均听力水平显著提高,视网膜血管密度显著降低。感音神经性听力损失患者视网膜中央毛细血管密度明显低于无听力损失患者(p值分别为0.039和0.024),神经性白塞病发病率明显高于无听力损失患者(p值分别为0.039和0.024),单因素回归分析证实了这一点。在多变量模型中引入显著因素后,神经-BD被确定为BD感音神经性听力损失最显著的单一预测因子(p值= 0.003)。结论:感觉神经性听力损失与中央视网膜血管密度降低及神经性白塞病之间的关系在白塞病中应予以考虑。
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来源期刊
CiteScore
5.30
自引率
7.70%
发文量
537
审稿时长
2-4 weeks
期刊介绍: Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.
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