Herbert S H Lee, Hilary H C Kwok, Muriel L Q Xiao, Cynthia K C Wai
{"title":"Biosynthetic graft versus autologous graft tympanoplasty: a prospective randomized controlled trial.","authors":"Herbert S H Lee, Hilary H C Kwok, Muriel L Q Xiao, Cynthia K C Wai","doi":"10.1007/s00405-024-09166-y","DOIUrl":"10.1007/s00405-024-09166-y","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to compare the graft success rate, hearing outcome, and operative time in patients undergoing tympanoplasty for tympanic membrane perforation with the use of either biosynthetic or autologous graft material.</p><p><strong>Methods: </strong>This was a prospective randomized controlled trial performed at a regional hospital. 41 patients were enrolled and randomized, with 20 patients allocated to the treatment arm (biosynthetic graft) and 21 patients allocated to the control arm (autologous graft). The primary outcome was graft success rate. The secondary outcomes were operative time and hearing outcomes (assessed by pure tone audiogram hearing threshold improvement and closure of air-bone gap at 6 months postoperatively).</p><p><strong>Results: </strong>There was no statistically significant difference in the graft success rate between the two groups (P = 0.645). There was also no statistically significant difference in the hearing outcomes (hearing thresholds improvement P = 0.886, air-bone gap improvement P = 0.651). However operative time was significantly shorter in the biosynthetic graft group compared with the autologous graft group (45.5 min vs. 72 min respectively; P < 0.001).</p><p><strong>Conclusion: </strong>This study demonstrates that tympanoplasty using a biosynthetic graft material can achieve comparable graft success rate and hearing outcomes as compared with conventional autologous graft tympanoplasty, but with the added benefits of a shortened operative time and avoiding incisions.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"2971-2975"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of high resolution laryngeal ultrasound in evaluation of laryngeal pathologies in children.","authors":"Oshin Guleria, Arunabha Chakravarti, Pooja Abbey","doi":"10.1007/s00405-025-09405-w","DOIUrl":"10.1007/s00405-025-09405-w","url":null,"abstract":"<p><strong>Introduction: </strong>The larynx is a crucial and vital structure present in the neck, having a key role in protection of lower airways, phonation and breathing. Life-threatening breathing issues can arise in newborns with laryngeal abnormalities. The most common symptom of laryngeal obstruction is stridor. A child with stridor usually causes a great deal of anxiety for the caregiver, so the medical practitioner should treat them as a clinical priority. The standard assessment of laryngeal abnormalities currently involves direct laryngoscopy and cross-sectional imaging (either CT or MRI) but rarely ultrasound. Ultrasound offers many advantages such as easily available, non invasive, affordable, lack of radiation, less time consuming and ability to do real-time imaging (with video for dynamic assessment). This study aims to know the diagnostic potential of laryngeal ultrasound in evaluation of laryngeal pathologies.</p><p><strong>Methods: </strong>A hospital based diagnostic study was carried on 50 children who had complaints of stridor, weak cry and hoarseness of voice. First LUS was performed and then ANL/MLB was performed and diagnosis was made. Findings of LUS were correlated with final diagnosis made on flexible nasopharyngolaryngoscopy /MLB.</p><p><strong>Results: </strong>50 children were enrolled in the study 26(52%) males and 24(48%). The median age was 3.50 months.LUS was performed without sedation in all patients.The sensitivity and specificity of LUS was 90.9% and 82.3% respectively.The PPV and NPV of LUS was 90.9%and 82.3% respectively.</p><p><strong>Conclusion: </strong>LUS is a promising tool in the evaluation of laryngeal pathologies. It is readily available and can be used in centers where flexible laryngoscopy is not available. It can be used as a alternative to diagnose laryngomalacia and vocal fold paresis/paralysis. There is no radiation exposure, and it is easily available, portable, and economical.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3115-3121"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Moyaert, K Vandermaesen, Q-A Parys, P Delaere, J Meulemans, G Hens, R Hermans, V Vander Poorten
{"title":"First branchial cleft anomalies in children: long-term outcome in 16 patients.","authors":"M Moyaert, K Vandermaesen, Q-A Parys, P Delaere, J Meulemans, G Hens, R Hermans, V Vander Poorten","doi":"10.1007/s00405-025-09203-4","DOIUrl":"10.1007/s00405-025-09203-4","url":null,"abstract":"<p><strong>Introduction: </strong>First branchial cleft anomalies (FBCA) are rare congenital head and neck malformations, often subject to incorrect diagnosis and treatment. We present our experience with FBCA, focusing on clinical presentation, diagnosis, perioperative relation to the facial nerve, surgical approach, complications and patient satisfaction.</p><p><strong>Methods: </strong>A consecutive cohort of 16 patients undergoing surgical treatment for FBCA between 1999 and 2021 was analyzed. Demographic and clinical information was extracted from their medical records. Additionally 14 patients were interviewed by telephone to assess postoperative outcomes and patient satisfaction using a Likert scale.</p><p><strong>Results: </strong>Sixteen patients (11 females, 5 males) were surgically treated at an age ranging from 7 months to 13 years. Type I and type II FBCA were evenly distributed. Lesions presented as cysts (n = 4), sinuses (n = 7) or fistulas (n = 5). The main symptoms were swelling, inflammation and discharge. Otologic symptoms were present in 31%. In 80% of patients, magnetic resonance imaging was needed to reach the correct diagnosis. Ten patients (63%) had a history of a surgical attempt in another center before definitive surgical treatment in our center. Complete excision was accomplished in all patients. Postoperative complications included limited Frey syndrome (n = 4), temporary hypertrophic scarring (n = 4), minimal paresis of the marginal mandibular branch of the facial nerve (n = 1) and limited external auditory canal stenosis (n = 1). One patient experienced a recurrence at the level of the external auditory canal, that required minor revision surgery. The average patient satisfaction score was 13.64 out of 15.</p><p><strong>Conclusion: </strong>Thorough clinical examination, awareness of the different entities and awareness of expert head and neck radiological advice are crucial for correct FBCA diagnosis and typing, determining the correct surgical approach. It is crucial that patients diagnosed with FBCA undergo surgery in specialized centers. Despite the challenging surgery and its potential complications, the overall patient satisfaction remains high post- treatment.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3151-3161"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonino Maniaci, Cosima C Hoch, Lise Sogalow, Benedikt Schmidl, Jerome R Lechien
{"title":"AI in clinical decision-making: ChatGPT-4 vs. Llama2 for otolaryngology cases.","authors":"Antonino Maniaci, Cosima C Hoch, Lise Sogalow, Benedikt Schmidl, Jerome R Lechien","doi":"10.1007/s00405-025-09371-3","DOIUrl":"10.1007/s00405-025-09371-3","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the diagnostic accuracy, appropriateness of additional examination recommendations, and consistency of therapeutic regimens by ChatGPT-4 and Llama2 based on real otolaryngology cases.</p><p><strong>Methods: </strong>A prospective controlled study was conducted on 98 anonymized otolaryngology cases. Clinical information was entered in ChatGPT-4 and Llama2 for reaching primary diagnoses, additional examination recommendations, and treatment strategies. Two independent otolaryngologists evaluated the AI outputs using the artificial intelligence performance instrument (AIPI), evaluating diagnostic accuracy, appropriateness of examination, and adequacy of treatment. Statistical comparisons were conducted between the AI systems and expert decisions. Interrater reliability was evaluated with kappa statistics.</p><p><strong>Results: </strong>ChatGPT-4 diagnosed 82% correctly, outperforming Llama2 at 76%. For additional examinations, ChatGPT-4 suggested relevant and appropriate tests in 88% of the studies, while Llama2 did so in 83%. Treatment appropriateness was achieved in 80% of the cases through ChatGPT-4 and 72% through Llama2. Sometimes, both systems suggested inappropriate tests. The interrater reliability was high for AIPI scores (kappa = 0.85).</p><p><strong>Conclusion: </strong>ChatGPT-4 and Llama2 have shown great potential as clinical decision-support tools in otolaryngology, with ChatGPT-4 exhibiting superior performance. At the same time, non-relevant recommendations indicate further refinement and human oversight to ensure safe application in clinical practice.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3293-3302"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amira Mohamed Taha, Areeba Fareed, Mandy Elewa, Mohammed Tarek Hasan, Toka Elboraay, Khaled Abouelmagd, Marwa Muhammed Abdeljawad
{"title":"Efficacy of bevacizumab in hereditary hemorrhagic telangiectasia: a systematic review and network meta-analysis.","authors":"Amira Mohamed Taha, Areeba Fareed, Mandy Elewa, Mohammed Tarek Hasan, Toka Elboraay, Khaled Abouelmagd, Marwa Muhammed Abdeljawad","doi":"10.1007/s00405-024-09177-9","DOIUrl":"10.1007/s00405-024-09177-9","url":null,"abstract":"<p><strong>Background: </strong>Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal multi-systemic vascular dysplasia caused by gene mutations that lead to recurrent epistaxis and other serious complications including mucocutaneous telangiectasias, gastrointestinal bleeding, and arteriovenous malformations. Treatment is limited to symptomatic relief with no approved standard therapy. Bevacizumab is a monoclonal antibody used primarily in treating metastatic malignancies and ophthalmology. Several studies have shown that bevacizumab is effective in the treatment of HHT-related epistaxis with a high safety profile.</p><p><strong>Purpose: </strong>This systematic review and network meta-analysis aims to explore the efficacy and safety of bevacizumab in the treatment of HHT epistaxis.</p><p><strong>Methods: </strong>A comprehensive literature search was done in many databases, including PubMed, Web of Science, Scopus, and the Cochrane Library. We conducted our network meta-analysis using R version 4.2.2 and R Studio version 2022.07.2. Dichotomous data was analyzed as risk ratio and 95% confidence interval and continuous data as mean difference and 95% confidence interval.</p><p><strong>Results: </strong>We included four randomized clinical trials in our network meta-analysis. Different doses of bevacizumab failed to yield any statistically significant difference in reducing the epistaxis severity score, the number of epistaxis episodes, the duration of epistaxis, or improving hemoglobin levels compared to placebo or other comparators. The pooled effect sizes for all outcomes were homogenous.</p><p><strong>Conclusion: </strong>Bevacizumab failed to show any significant difference compared to tranexamic acid, estriol, or placebo. These findings underscore the challenges in addressing HHT-related symptoms and highlight the ongoing need for innovative and more effective interventions.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"2821-2832"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B B Büyük, F Toprak, Caner Kılıç, T Tunçcan, Ceren Öztop
{"title":"The effects of prognostic nutritional index, systemic immune inflammation index and HALP score on fistula formation, recurrence and mortality in laryngeal cancer patients.","authors":"B B Büyük, F Toprak, Caner Kılıç, T Tunçcan, Ceren Öztop","doi":"10.1007/s00405-025-09223-0","DOIUrl":"10.1007/s00405-025-09223-0","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to investigate the effects of prognostic nutritional index (PNI), systemic immune inflammation index (SII) and hemoglobin, albumin, lymphocyte, platelet (HALP) score on fistula formation, recurrence and mortality in patients with laryngeal cancer.</p><p><strong>Method: </strong>The study included 77 patients who underwent total laryngectomy operation between 2018 and 2021. 66 (85.7%) patients underwent primary and 11 (14.3%) patients underwent salvage total laryngectomy. PNI, SII and HALP scores and cutt-off values of all patients were determined and the relationships between pharyngocutaneous fistula (PCF) formation, recurrence and mortality were statistically analysed. The patients with a score less than the cut-off value were divided into two groups as Group 1, and the patients with a score equal to or greater than the cut-off value were divided into two groups as Group 2.</p><p><strong>Results: </strong>The effect of PNI, SII and HALP on the development of FKF was not significant (P = 0.110, P = 0.135, P = 0.358). The effect of high SII and low HALP score on the development of recurrence was statistically significant (P = 0.001, P = 0.012). Low PNI increased the development of recurrence, but this increase was not statistically significant (P = 0.075). Overall survival rate was 68.8%. The effect of low PNI and HALP on survival was statistically significant (P = 0.011, P = 0.021). The effect of high SII on survival was not significant (P = 0.533).</p><p><strong>Conclusion: </strong>Low PNI index and HALP score and high SII index are cost-effective simple prognostic biomarkers that are significant in the development of FCF, as well as in the evaluation of recurrence and overall survival in the long-term follow-up of these patients.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3203-3209"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonio Della Volpe, Chiara Bruno, Pietro De Luca, Massimo Ralli, Arianna Di Stadio
{"title":"Adelmidrol to fight upper airways inflammation in children: a pilot case control study to safety and efficacy.","authors":"Antonio Della Volpe, Chiara Bruno, Pietro De Luca, Massimo Ralli, Arianna Di Stadio","doi":"10.1007/s00405-025-09375-z","DOIUrl":"10.1007/s00405-025-09375-z","url":null,"abstract":"<p><strong>Purpose: </strong>Inflammations of the upper respiratory tract (URT) are common both in adults and children and they are generally treated using aerosol therapy with mucolytic medications and steroids. When these inflammations affect children, the treatment must be rapid and resolutive to prevent complications. Steroids present some contraindications, i.e. alteration of smell, that must be considered especially in children. Therefore, alternative treatments that have similar efficacy but limited adverse effects should be considered. This study aims at evaluating the efficacy of Adelmidrol to treat inflammation of the URT in children.</p><p><strong>Methods: </strong>Case-Control study. Control group used standard treatment for URT inflammation (mucolytics and steroids); treatment groups were treated by Adelmidrol spray. Sixty children (age range 2.5-4.5 years) were randomly assigned to (i) control group, (ii) treatment group 1 (TG1)- Adelmidrol nasal spray only and (iii) treatment group 2 (TG2), in which Adelmidrol was administered in both nasal and oral spray solution. The URT and the tympanic membrane were evaluated at T0, T1 (30 days) and T2 (90 days). The treatments were performed for 90 consecutive days.</p><p><strong>Results: </strong>At the end of the treatment, TG2 (combination of nasal and oral sprays) had the best outcomes both on URT findings (χ²: p = 0.0004) and tympanic membrane conditions (χ²: p = 0.03). TG1 showed similar outcome of CG.</p><p><strong>Conclusions: </strong>These preliminary results in our group of 60 children showed that Adelmidrol had the same efficacy of standard treatment when used as nasal spray only and was better than the standard treatment when used combining nasal and oral sprays. The molecule seems to offer the same benefit of standard treatment without side effects. If confirmed on a larger sample, the use of Adelmidrol could be suggested as an alternative to traditional treatment for the inflammation of URT in children.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3075-3083"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ankit Ajmera, Nikeith John, Adrienne Morey, Nigel Biggs, Sean Flanagan, Peter Earls, Daniel Brown, Payal Mukherjee
{"title":"Morphological studies of labyrinthine tissue in patients affected with Meniere's disease and vestibular schwannoma following labyrinthectomy.","authors":"Ankit Ajmera, Nikeith John, Adrienne Morey, Nigel Biggs, Sean Flanagan, Peter Earls, Daniel Brown, Payal Mukherjee","doi":"10.1007/s00405-024-09160-4","DOIUrl":"10.1007/s00405-024-09160-4","url":null,"abstract":"<p><strong>Background: </strong>Meniere's disease (MD) is a disabling disease of the inner ear, having a substantial effect on a patient's quality of life. While various postulations regarding its aetiology exists, due to the difficulty with accessing inner ear tissue, there have been limited histological studies in patients with active MD.</p><p><strong>Methods: </strong>Tissue was collected during labyrinthectomy from 8 patients with intractable MD who had failed medical therapy (22 samples), and 9 patients undergoing translabyrinthine resection of vestibular schwannoma (19 samples). 20 additional samples were obtained from 2 cadavers without a history of inner ear disease. Samples were assessed with routine histology and a panel of immunohistochemical markers to assess any differences between the groups.</p><p><strong>Results: </strong>No MD samples demonstrated significant inflammatory infiltrate, evidence of denervation of the sensory epithelium, fibrosis, or thickening of blood vessel wall stroma. Novel findings included confirmation that no lymphatic channels of usual type were present and that the subepithelial stromal cells are strongly positive for S100, suggesting possible perineurial origin. There were no consistent differences in expression of Claudin or Aquaporin between the MD and VS patient samples.</p><p><strong>Conclusion: </strong>This is one of the largest comparative histological study utilising operative samples from inner ear of living donors with active intractable MD and control patients with VS. There were no significant morphological differences between the two groups, suggesting that the aetiology lies elsewhere within the vestibular system. Examination of endolymphatic sac tissue is therefore a priority for future work.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"2911-2920"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142893267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlatıon between PET-CT uptake values and pathologıcaly features ın head and neck cancer.","authors":"Atakan Sarıgül, Vahit Mutlu","doi":"10.1007/s00405-025-09228-9","DOIUrl":"10.1007/s00405-025-09228-9","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the correlation between SUV-Max values and pathological outcomes in head and neck squamous cell carcinoma (HNSCC) and determine the predictive power of SUV-Max for disease prognosis.</p><p><strong>Data sources: </strong>Retrospective analysis of medical records and PET-CT imaging results from patients diagnosed with HNSCC at our institution between 2014 and 2023.</p><p><strong>Review methods: </strong>Examination of SUV-Max values from F18-FDG PET-CT scans and their association with pathological findings such as perineural invasion, lymphovascular invasion, and neck lymph node metastasis. Statistical analysis was conducted to establish cutoff values and assess the significance of correlations.</p><p><strong>Results: </strong>Our study identified significant cutoff values for PET-CT SUV-Max that correlate with the pathological features of head and neck cancer. For primary tumors, a SUV-Max cutoff of 14.71 predicted neck metastasis with a sensitivity of 67.6% and specificity of 64.2%, demonstrating moderate diagnostic accuracy with an AUC of 0.648. Perineural invasion was optimally predicted at a cutoff of 13.28, with a sensitivity of 74%, specificity of 67.3%, and an AUC of 0.728. Similarly, a cutoff of 13.28 for lymphovascular invasion yielded a sensitivity and specificity of 63%, with an AUC of 0.628. Additionally, neck lymph node metastasis was effectively assessed with a SUV-Max cutoff of 2.74, achieving a sensitivity of 62.2%, specificity of 67%, and an AUC of 0.694. These cutoff values highlight the potential of SUV-Max in enhancing diagnostic precision for both primary tumors and lymph node assessments in head and neck oncology.</p><p><strong>Conclusion: </strong>SUV-Max values from PET-CT scans are significant predictors of pathological outcomes in HNSCC, aiding in the stratification of patient prognosis and guiding clinical decision-making.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3211-3220"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143613545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edward C Kuan, Arash Abiri, Vidit Talati, David T Liu
{"title":"In response to Favier et al.: acknowledging variability and evidence gaps in skull base reconstruction practices.","authors":"Edward C Kuan, Arash Abiri, Vidit Talati, David T Liu","doi":"10.1007/s00405-025-09224-z","DOIUrl":"10.1007/s00405-025-09224-z","url":null,"abstract":"","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"3385-3386"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}