European Archives of Oto-Rhino-Laryngology最新文献_第10页

Mucosal integrity of the larynx and hypopharynx and the response to proton pump inhibitors in patients with laryngopharyngeal reflux.

IF 1.9 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-02-01 DOI: 10.1007/s00405-025-09214-1

Clara Mota Randal Pompeu, Thiago Meneses Araújo Leite Sales, Lucas Antonio Duarte Nicolau, Anna Caroline Rodrigues de Souza Matos, Aline Almeida Figueiredo Borsaro, Tanila Aguiar Andrade Coutinho, Larissa Freire Alves Nogueira, Fábio Rocha Fernandes Távora, Miguel Ângelo Nobre E Souza, Daniel Siffrim, Marcellus Henrique Loiola Ponte de Souza

{"title":"Mucosal integrity of the larynx and hypopharynx and the response to proton pump inhibitors in patients with laryngopharyngeal reflux.","authors":"Clara Mota Randal Pompeu, Thiago Meneses Araújo Leite Sales, Lucas Antonio Duarte Nicolau, Anna Caroline Rodrigues de Souza Matos, Aline Almeida Figueiredo Borsaro, Tanila Aguiar Andrade Coutinho, Larissa Freire Alves Nogueira, Fábio Rocha Fernandes Távora, Miguel Ângelo Nobre E Souza, Daniel Siffrim, Marcellus Henrique Loiola Ponte de Souza","doi":"10.1007/s00405-025-09214-1","DOIUrl":"https://doi.org/10.1007/s00405-025-09214-1","url":null,"abstract":"Purpose: To evaluate whether impairment of integrity of laryngeal and hypopharyngeal mucosa in laryngopharyngeal reflux (LPR) could be related to response to proton pump inhibitors (PPIs).Methods: Chronic hoarseness with Reflux Finding Score (RFS) > = 7 was evaluated using the Reflux Disease Questionnaire (RDQ) and Reflux Symptoms Index (RSI). Upper endoscopy was performed and samples of the laryngeal posterior commissure were collected to evaluate ex vivo laryngeal mucosal integrity by transepithelial resistance (TER) using Ussing chamber. In vivo, hypopharyngeal integrity was measured using intraluminal impedance. Clinical responders scored < 13 and had a drop of at least 50% in the initial RSI after 8 weeks of pantoprazole.Results: Eighteen patients completed the protocol, Esophagitis was detected in 28% of the patients, and one patient presented acid exposure above 6%. After treatment, 66.67% responded to PPI. Laryngeal basal TER and TER drops after the weakly acidid challenge showed no difference between PPI responders and non-responders. Hypopharyngeal basal impedance was similar between the groups. After acid exposure test, there was a lower impedance in non-responders.Conclusion: In laryngopharyngeal reflux, hypopharyngeal mucosal integrity was lower in PPI non-responders. These preliminary results suggest that the weaker laryngopharyngeal mucosa in refractory LPR may require new therapies aimed at improving barrier function.Level of evidence: N/A.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Slide laryngotracheopexy for idiopathic subglottic stenosis.

IF 1.9 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-02-01 DOI: 10.1007/s00405-025-09226-x

Zoltán Tóbiás, Ádám Bach, László Szakács, Miklós Csanády, Andrea Ambrus, László Rovó

{"title":"Slide laryngotracheopexy for idiopathic subglottic stenosis.","authors":"Zoltán Tóbiás, Ádám Bach, László Szakács, Miklós Csanády, Andrea Ambrus, László Rovó","doi":"10.1007/s00405-025-09226-x","DOIUrl":"https://doi.org/10.1007/s00405-025-09226-x","url":null,"abstract":"Objectives: Idiopathic subglottic stenosis (iSGS) is a rare fibroinflammatory disorder characterized by scar tissue formation in the subglottic and tracheal regions. This study evaluated the long-term outcomes of a novel, single-step surgical technique that redefines the glottic and subglottic airway using local tracheal grafts.Methods: Thirteen patients (2 male and 11 female) diagnosed with iSGS who underwent slide laryngotracheopexy were enrolled in this study. The diagnosis of iSGS was confirmed through endoscopic assessment, CT scanning, and autoimmune blood testing. Patients completed post-operative Voice Handicap Index (VHI), Quality of Life (QoL), and MD Anderson Dysphagia Inventory (MDADI) questionnaires, and spirometry assessments were conducted.Results: All patients were successfully extubated in the operating room following surgery. None of the patients required intensive care unit treatment. The average hospital stay was 14 days. A temporary tracheotomy was needed in one case because of excessive crusting. Adjuvant endolaryngeal laser surgery was performed in three cases. In one case, mitomycin-C therapy was administered to treat granulation. Post-operative quality of life (QoL) assessment, peak inspiratory flow (PIF), and scores from the MDADI and VHI questionnaires were 9.0 (± 2.2), 2.8 l/s (± 0.83), 95.6 (± 4.3), and 18.7 (± 13.4), respectively.Conclusion: Slide laryngotracheopexy was a safe and dependable technique for cases classified as Cotton-Myers II-IV grade iSGS. The use of a tracheal flap was advantageous to ensure optimal mucosal function. Slide laryngotracheopexy may be employed following multiple endolaryngeal interventions, whereas adjuvant CO2 laser surgery or mitomycin-c therapy may be considered in cases involving granulation tissue formation.Level of evidence: 4: Study design: Retrospective case series review.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of nasal mucociliary clearance in patients with psoriasis. 评估银屑病患者的鼻黏膜纤毛清除率。

IF 1.9 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-02-01 Epub Date: 2024-10-30 DOI: 10.1007/s00405-024-09055-4

Abitter Yücel, Cahit Yavuz, Mustafa Güllüev, Hilal Yücel, Ekrem Özsöz, Sümeyye Gencer Çulha, Mehmet Akif Alan, Mehmet Akif Eryılmaz

{"title":"Evaluation of nasal mucociliary clearance in patients with psoriasis.","authors":"Abitter Yücel, Cahit Yavuz, Mustafa Güllüev, Hilal Yücel, Ekrem Özsöz, Sümeyye Gencer Çulha, Mehmet Akif Alan, Mehmet Akif Eryılmaz","doi":"10.1007/s00405-024-09055-4","DOIUrl":"10.1007/s00405-024-09055-4","url":null,"abstract":"Purpose: Psoriasis is an autoimmune pathology characterized by chronic inflammation with known multiorgan involvement. In the literature, there are few studies investigating the effects of psoriasis on upper respiratory tract mucosa. Our aim in our study was to investigate the possible effect of psoriasis disease severity and duration on nasal mucosa.Methods: A study group was formed from patients with psoriasis and disease duration, Psoriasis Area Severity Index (PASI) and Nasal Obstruction Symptom Evaluation (NOSE) scores of these patients were recorded. Demographic data were noted in all participants with the participation of control group patients, saccharin test was performed to evaluate the nasal mucosa and nasal mucociliary clearance (NMC) times were measured. Psoriasis patients with pathology that may cause nasal obstruction were excluded from the study.Results: A total of 59 people (30 patients and 29 controls) aged 20-65 years were included in the study. There was no difference in age and gender distribution between the two groups. No statistically significant difference in the NMC time between two groups. In the patients group, a correlation was observed between the NMC time to the NOSE test, but no correlation was observed between the NMC time to the duration of the disease and the PASI score.Conclusion: In our study, no difference was observed in NMC time between the two groups and according to the duration or severity of the disease. In addition, NOSE score of patients was also relatively low. No significant impact of psoriasis on nasal functions was found.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"807-811"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of swallowing disorders in patients with chronic rhinosinusitis and nasal polyposis in comparison to healthy controls: a Survey of 50 cases. 慢性鼻窦炎和鼻息肉病患者与健康对照组相比吞咽障碍的风险：一项50例的调查

IF 1.9 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-02-01 Epub Date: 2024-12-23 DOI: 10.1007/s00405-024-09078-x

Abdul-Latif Hamdan, Jad Hosri, Nadine El Hadi, Jonathan Abou Chaar, Zeina Semaan, Sacha Kodeih, Zeina Korban

{"title":"Risk of swallowing disorders in patients with chronic rhinosinusitis and nasal polyposis in comparison to healthy controls: a Survey of 50 cases.","authors":"Abdul-Latif Hamdan, Jad Hosri, Nadine El Hadi, Jonathan Abou Chaar, Zeina Semaan, Sacha Kodeih, Zeina Korban","doi":"10.1007/s00405-024-09078-x","DOIUrl":"10.1007/s00405-024-09078-x","url":null,"abstract":"Purpose: To investigate the risk of swallowing disorders and the frequency and intensity of vocal tract symptoms in patients with chronic rhinosinusitis and nasal polyposis (CRSwNP).Methods: Adult patients diagnosed with CRSwNP presenting to the rhinology clinic of a tertiary referral center between March 2023 and March 2024, were recruited. Patients with acute or recent history of respiratory tract infections, tonsillitis, pharyngitis or otitis, were excluded. The frequency and severity of nasal symptoms and their impact on quality of life was assessed using the Sinonasal Outcome Test (SNOT-22). The Eating Assessment Tool (EAT-10) was used to evaluate the risk of swallowing disorders, and the Vocal Tract Discomfort Scale (VTDS) was used to evaluate the frequency and intensity of vocal tract symptoms.Results: Twenty-five patients with CRSwNP and 25 controls were recruited for this study. There was a statistically significant difference in the mean EAT-10 score between the study group and control group (3.52 ± 4.68 vs.0.88 ± 1.83; p = 0.013). There was also a statistically significant difference in the mean VTDS score between the study group and control group (12.56 ± 7.9 vs. 4 ± 4.64; p < 0.001). There was a positive moderate correlation between the VTDS score and the SNOT-22 score (r = 0.595; p < 0.001).Conclusion: The study indicates that patients with CRSwNP have a higher risk for swallowing disorders and are more likely to experience vocal tract symptoms than healthy controls.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"821-825"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AI in oncology: comparing the diagnostic and therapeutic potential of claude 3 opus and ChatGPT 4.0 in HNSCC management. 肿瘤学中的人工智能：比较 claude 3 opus 和 ChatGPT 4.0 在 HNSCC 管理中的诊断和治疗潜力。

IF 1.9 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-02-01 Epub Date: 2024-11-14 DOI: 10.1007/s00405-024-09062-5

Mohd Rafi Lone, Shahab Saquib Sohail, Abdul Rahman, Ashfaq Ahmad Najar

引用次数: 0

Advancing evidence-based surgical strategies for pulsatile tinnitus. Comment on the author's reply. 推进以证据为基础的搏动性耳鸣手术策略。对作者的回复发表评论。

IF 1.9 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-02-01 Epub Date: 2024-12-12 DOI: 10.1007/s00405-024-09132-8

Aynur Aliyeva

引用次数: 0

European consensus on endoscopic surgery for bilateral vocal fold immobility: classification and nomenclature. 欧洲共识内窥镜手术治疗双侧声带不动：分类和命名。

IF 1.9 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-02-01 Epub Date: 2025-01-02 DOI: 10.1007/s00405-024-09133-7

Emilie A C Dronkers, Chadwan Al Yaghchi, Jerome R Lechien, Christian Sittel, Ahmed Geneid

{"title":"European consensus on endoscopic surgery for bilateral vocal fold immobility: classification and nomenclature.","authors":"Emilie A C Dronkers, Chadwan Al Yaghchi, Jerome R Lechien, Christian Sittel, Ahmed Geneid","doi":"10.1007/s00405-024-09133-7","DOIUrl":"10.1007/s00405-024-09133-7","url":null,"abstract":"Introduction: There are inconsistencies in how different endoscopic procedures to manage Bilateral Vocal Fold Immobility (BVFI) have been described in the literature. This limits our ability to compare functional outcomes. There is no unifying international terminology available that precisely describes the anatomical boundaries and extent of the different types of treatment. A pan-European consensus regarding terminology of different endoscopic surgical procedures to manage BVFI in adults was developed.Methods: Thirty-one expert laryngologists and phoniatricians of the European Laryngological Society (ELS) or Union of the European Phoniatricians (UEP), participated in a modified Delphi process. They voted on an initial series of 13 proposed statements, including graphical visualization of different endoscopic surgical techniques for BVFI. Statements reaching > 70% of agreement in the first voting round were accepted. In the second voting round, eight revised and newly proposed statements were accepted with an increased threshold of > 80%.Results: Fourteen statements were anonymously validated through two voting rounds. The following categories of endoscopic arytenoid and vocal fold surgery were defined: total arytenoidectomy, partial arytenoidectomy (subclassified into subtotal, anteromedial, posteromedial and superomedial), posterior cordectomy (subclassified into ligamental, transmuscular and ventriculocordectomy) and transverse cordotomy (subclassified into posterior cordotomy and ventriculocordotomy). The suffixes 'with mucosal preservation', 'with laterofixation' and 'combined procedure' were defined too.Conclusion: This ELS-UEP consensus on endoscopic arytenoid and vocal fold surgery for BVFI provides a practical nomenclature and classification to improve reporting in literature and clinical practice and to allow comparison of functional outcomes.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"937-944"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142920630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Illness perceptions in cochlear implant users - a longitudinal study. 人工耳蜗使用者的疾病感知--一项纵向研究。

IF 1.9 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-02-01 Epub Date: 2024-09-19 DOI: 10.1007/s00405-024-08963-9

Effi Katharina Lehmann, Katharina Heinze-Köhler, Cynthia Glaubitz, Tim Liebscher, Max Engler, Ulrich Hoppe

{"title":"Illness perceptions in cochlear implant users - a longitudinal study.","authors":"Effi Katharina Lehmann, Katharina Heinze-Köhler, Cynthia Glaubitz, Tim Liebscher, Max Engler, Ulrich Hoppe","doi":"10.1007/s00405-024-08963-9","DOIUrl":"10.1007/s00405-024-08963-9","url":null,"abstract":"Purpose: 'Illness perceptions' refers to the thoughts and ideas a person has about an illness. According to Leventhal's Self-Regulatory Model (SRM), changing the threatening illness perceptions of cochlear implant (CI) recipients can be a further step in optimizing hearing outcomes with the CI. The aims of the present study were to assess users' illness perceptions and to determine whether perceptions change during six months of CI rehabilitation.Methods: One hundred and thirty-eight participants completed the Brief Illness Perception Questionnaire (Brief IPQ), assessing their illness perceptions on nine scales. Data were collected at a German CI center at first CI fitting and six-month follow-up. After first fitting, participants underwent intensive rehabilitation including auditory training, medical, audiological and psychological treatments.Results: At both assessments, participants tended to view their hearing impairment as a severe threat. On the Brief IPQ, the 'consequences' assessment improved during CI rehabilitation, which can be explained by the CI-induced hearing improvement. However, 'understanding' and 'identity' assessments worsened. This could be because CI recipients only come to realize the full complexity of their hearing impairment during rehabilitation. The other scales and the total score remained unaffected.Conclusions: Current practice in CI rehabilitation seems to be insufficient to improve threatening illness perceptions (except for perceived consequences). This may be because standard information often fails to reach the patients. The development and empirical validation of an intervention program to address individual illness perceptions in CI recipients could be helpful in this context. Further research will be needed to confirm the results.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"981-989"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-definition otoscopic device for humanitarian mission: how i do it.

IF 1.9 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-02-01 DOI: 10.1007/s00405-025-09219-w

Jerome R Lechien, Antonino Maniaci, Margaret Jepkoech Kipsang, Mary Kibor, Luigi A Vaira

引用次数: 0

PATH classification: a proposal for patients with HNSCC treated with salvage surgery. PATH 分类：针对接受挽救手术治疗的 HNSCC 患者的建议。

IF 1.9 3区医学

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-02-01 Epub Date: 2024-09-23 DOI: 10.1007/s00405-024-08961-x

Albert Llansana, David Virós Porcuna, Rosselin Vasquez, Arnau Parellada, Cristina Valero, Anna Holgado, Xavier León

{"title":"PATH classification: a proposal for patients with HNSCC treated with salvage surgery.","authors":"Albert Llansana, David Virós Porcuna, Rosselin Vasquez, Arnau Parellada, Cristina Valero, Anna Holgado, Xavier León","doi":"10.1007/s00405-024-08961-x","DOIUrl":"10.1007/s00405-024-08961-x","url":null,"abstract":"Purpose: The aim of this study is to propose a classification for patients with recurrent head and neck squamous cell carcinoma (HNSCC) treated with salvage surgery based on the location of the primary tumor and data commonly found in the pathological report of the resection.Methods: Retrospective study of 665 patients with HNSCC treated with a salvage surgery after a local and/or regional recurrence of the tumor.Results: We propose a new postoperative classification for patients with recurrent HNSCC treated with salvage surgery. PATH classification stratifies patients into 4 stages based on the glottic or non-glottic location of the primary tumor, the local and regional pathologic extension of the tumor, the status of the surgical margins, and the presence of lymph node metastases with extracapsular spread. The PATH classification was more homogeneous in the prognosis of patients included in each of its stages, and it had a better prognostic discrimination capacity between stages than the rpTNM classification. According to the PATH classification, the 5-year disease-specific survival was: PATH I (n = 306) 82.8%; PATH II (n = 119) 47.1%; PATH III (n = 202) 24.4%; PATH IV (n = 38) 3.7%. For the rpTNM classification, the 5-year disease-specific survival was: stage I (n = 119) 85.1%; stage II (n = 134) 68.4%; stage III (n = 111) 59.5%; stage IV (n = 301) 33.3%.Conclusion: The PATH classification for HNSCC patients with local and/or regional recurrence treated with salvage surgery had a better prognostic capacity than the rpTNM classification.Level of evidence: Level IV.","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":"971-979"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0