European Archives of Oto-Rhino-Laryngology最新文献

{"title":"Radiological evaluation of facial nerve and facial canal in patients with Bell's palsy.","authors":"Fırat Onur, Neşe Uçar, Derya Cebeci, Batuhan Bileyci, Burak Bük, Ömer Necati Develioğlu","doi":"10.1007/s00405-025-09325-9","DOIUrl":"https://doi.org/10.1007/s00405-025-09325-9","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the diameter of the facial nerve (FN) and facial canal (FC) at different segments in Bell's palsy (BP) patients and compare the facial nerve/facial canal width ratio (FN/FC) of the the affected and healthy sides to determine the entrapped sites.</p><p><strong>Methods: </strong>This retrospective study enrolled 47 patients with BP that were referred to a tertiary referral hospital. From patients' records, initial House-Brackmann grades, cranial computurized tomography (CT) and contrast enhanced temporal magnetic resonance imaging (MRI) scans were revieved. FC and FN diameter measurements were performed at the midpoint of labyrinthine segment, geniculate ganglion and tympanic segment in the axial plane, and mastoid segment in the sagittal plane. Contrast-enhanced segments on MRI were evaluated.</p><p><strong>Results: </strong>There was no statistically significant difference between the FC diameters of the affected and the healthy sides on CT at any measured segments. FN diameter was increased significantly for all segments except mastoid segment on the affected side compared to the healthy side. FN/FC ratio was significantly greater on the affected side than the healthy side in all measured segments. Evident contrast enhancement was observed in all affected FNs, with geniculate ganglion and labyrinthine segment being the most common sites with contrast enhancement on MRI.</p><p><strong>Conclusion: </strong>Anatomical differences in FC may not be the main predisposing factor in BP. As the geniculate ganglion and labyrinthine segments had the highest FN/FC ratio and showed clear contrast enhancement on MRI, these findings may indicate a higher risk of inflammation and entrapment in these segments.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of peroperative ultrasound used by the surgeon in parathyroidectomy on operation time.","authors":"Mehmet Turan Cicek, Mehmet Aslan, Cigdem Firat Koca","doi":"10.1007/s00405-025-09319-7","DOIUrl":"https://doi.org/10.1007/s00405-025-09319-7","url":null,"abstract":"<p><strong>Purpose: </strong>One of the endocrine conditions that endocrinologists see the most frequently is primary hyperparathyroidism, which is brought on by a parathyroid adenoma. Minimally invasive parathyroidectomy (MIP) has become the first line of treatment for primary hyperparathyroidism due to solitary parathyroid adenoma. Surgeon-performed ultrasonography (SUS), which has been found to be extremely accurate in localizing aberrant glands, has been employed preoperatively to augment the sensitivity of high-resolution ultrasonography (hUS).</p><p><strong>Methods: </strong>Two groups were randomly created from cases that underwent parathyroid surgery. In the first group, surgery was performed on 31 patients, taking into account the ultrasound results reported by radiology and the Technetium-99 m sestamibi scintigraphy results interpreted by the nuclear medicine clinic. In addition to the ultrasound results reported by radiology and the scintigraphy results interpreted by the nuclear medicine clinic, surgery was performed on 18 patients in the second group, that the surgeon applied ultrasound to them before the operation and separately evaluating the location of the parathyroid adenoma. Surgery time, hospital stay, pre and postoperative calcium and parathormon values were compared between the two groups.</p><p><strong>Results: </strong>When groups 1 and 2 were compared in terms of surgical time and hospital stay, there was a statistically significant difference between the two groups (p < 0.05). In Group 2, the duration of operation and hospital stay was significantly shortened. There was no statistically significant difference between the groups in terms of pre- and postoperative calcium and parathormone values (p > 0.05).</p><p><strong>Conclusions: </strong>We believe that the time required for surgery after a radiologist and surgeon performing ultrasonography is less than that required for surgery after radiologist performed ultrasonography demonstrating the efficacy of the surgery plus a radiologist and surgeon performing ultrasonography combination. We determined that the surgery time was statistically shorter in patients who underwent a radiologist and surgeon performing ultrasonography.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of sensorineural hearing loss and its relation to Optical Coherence Tomography Angiography findings in Behcet's disease.","authors":"Maha S I Abdelrahman, Mohamed G A Saleh, Maha Abdelgaber A Aly, Shaimaa Salah","doi":"10.1007/s00405-025-09280-5","DOIUrl":"10.1007/s00405-025-09280-5","url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to analyze auditory involvement in patients with Behcet's disease and its association with Optical Coherence Tomography Angiography findings and disease manifestations.</p><p><strong>Methods: </strong>This study included 54 eyes and 68 ears of 34 adults with Behcet's disease in comparison to 30 eyes and 60 ears of healthy controls. Clinical, laboratory and ophthalmological evaluation including Optical Coherence Tomography Angiography was done. Audiological assessment included otoscopic examination, immitancemetry and pure tone and speech audiometry.</p><p><strong>Results: </strong>Sensorineural hearing loss was observed in 32.35% of the studied cases. Behcet's disease patients showed significantly higher average hearing level and significant reduction of retinal vessel density compared to controls. Patients with sensorineural hearing loss demonstrated significantly lower central retinal capillary vessel density and higher neuro-Behcet's disease incidence in comparison to those without hearing loss (p-value = 0.039 and 0.024, respectively), which was confirmed by univariate regression analysis. After entering significant factors into the multivariate model, neuro-BD was identified as the most significant single predictor of sensorineural hearing loss in BD (p-value = 0.003).</p><p><strong>Conclusions: </strong>The association between sensorineural hearing loss and central retinal vessel density reduction and neuro- Behcet's disease should be considered in Behcet's disease.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of vestibular rehabilitation using unidirectional rotation paradigm in VOR asymmetry: systematic review and meta-analysis.","authors":"Miriam González-García, Lucía Prieto-Sánchez-de-Puerta, María Alharilla Montilla-Ibáñez, Emilio Domínguez-Durán, Serafín Sánchez-Gómez, Ana Sedeño-Vidal","doi":"10.1007/s00405-025-09282-3","DOIUrl":"https://doi.org/10.1007/s00405-025-09282-3","url":null,"abstract":"<p><strong>Purpose: </strong>Unilateral vestibular dysfunction leads to significant asymmetry in the horizontal vestibulo-ocular reflex (VOR) during swift head movements. This reflex can be enhanced through rehabilitation exercises and visual-vestibular adaptation techniques. This systematic review aims to evaluate the current evidence on the effectiveness of unidirectional rotation treatments for improving symptoms and function in patients with vestibular disorders.</p><p><strong>Methods: </strong>A systematic review was conducted following the PRISMA 2020 guidelines, using databases such as PubMed, Cochrane Library, EMBASE, and Scopus. Included were experimental studies, randomized controlled trials (RCTs), or pilot RCTs. Meta-analysis was performed based on the findings of these studies.</p><p><strong>Results: </strong>Among 24 articles identified, three addressed the systematic review's question, two observational studies (one retrospective and one prospective) and a RCT. Studies included data from a total of 200 participants with vestibular disorders (n = 96; 48% males) for the meta-analysis. A meta-analysis, including a subgroup analysis, was conducted to assess the improvement in VOR asymmetry following vestibular rehabilitation. The analysis compared pre- and post-rehabilitation directional preponderance (DP) across three studies. Results showed a significant improvement in VOR asymmetry, with a mean difference of 18.72% in favour of rehabilitation.</p><p><strong>Conclusion: </strong>Our findings substantiate the efficacy of unilateral vestibular stimulation in reducing asymmetry in the VOR among patients with vestibular dysfunction. This modality represents a promising rehabilitation strategy, significantly enhancing vestibular function and patient outcomes.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barbecue roll maneuver for horizontal canal benign paroxysmal positional vertigo: a systematic review of randomized controlled trials.","authors":"Anas R Alashram","doi":"10.1007/s00405-025-09304-0","DOIUrl":"https://doi.org/10.1007/s00405-025-09304-0","url":null,"abstract":"<p><strong>Purpose: </strong>This review aims to investigate the effects of the Barbecue roll maneuver on horizontal semicircular canal benign paroxysmal positional vertigo (HC-BPPV) recovery.</p><p><strong>Methods: </strong>Multiple databases, including \"PubMed, PEDro, REHABDATA, MEDLINE, SCOPUS, EMBASE, and Web of Science\" were searched from inception to October 2024\". Experimental studies that included patients with HC-BPPV that performed the Barbecue roll maneuver independently or in combination with other treatments, compared with active, passive, or no controls, assessed HC-BPPV symptoms, were included in this analysis. The \"Physiotherapy Evidence Database (PEDro)\" scale was used to investigate the methodological quality of the included studies.</p><p><strong>Results: </strong>Nine studies met the inclusion criteria with 768 HC-BPPV patients (mean age = 56.16 years; 64% female; 52% right-side HC-BPPV; 90% geotropic HC-BPPV). The PEDro scores ranged from 3 to 8, with a median of 6. The findings showed that the Barbecue roll maneuver is not superior in reducing HC-BPPV symptoms compared to other maneuvers, such as the Gufoni, the Gufoni-Appiani and the Li repositioning.</p><p><strong>Conclusions: </strong>The initial findings indicated that the Barbecue roll maneuver is considered a treatment option for treating geotropic HC-BPPV. Performing Barbecue roll maneuver for 1 to 3 times can yield meaningful effects. Accurate diagnosis of HC-BPPV is essential for optimal treatment outcomes. The success rate of recovery depends on patient characteristics and therapist proficiency. Additional studies are recommended.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is ductoplasty required following transoral sialolithotomy? - A case series.","authors":"Katie Holland, Jinnee U J Lee, Olga Gomeniouk, Grant S Owen, Richard Raad, Mihir Bhayani","doi":"10.1007/s00405-025-09324-w","DOIUrl":"https://doi.org/10.1007/s00405-025-09324-w","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to determine if there was a difference in postoperative outcomes and complications between patients who underwent traditional two-layer closure (ductoplasty and floor of mouth) after Wharton's duct sialolithatomy during hybrid sialendoscopy compared to those who underwent single layer closure of only the floor of mouth.</p><p><strong>Methods: </strong>Retrospective case series of a single surgeon's patients who underwent hybrid sialendoscopy at an urban tertiary care hospital. Demographic, preoperative, intraoperative, and postoperative information was collected from patients who underwent hybrid sialendoscopy with transoral sialolithotomy of Wharton's duct from 2020 to 2023. Data included salivary glands explored, intraoperative complications, ductal repair, postoperative complications, and recurrence of salivary symptoms.</p><p><strong>Results: </strong>32 patients underwent hybrid sialendoscopy. Of those, 28.1% (n = 9) underwent traditional two-layer closure, and in 71.9% (n = 23) had single layer closure. 2.6% (n = 1) had a postoperative infection. There were no immediate postoperative complications reported in those with single layer closure. There was no statistical difference in postoperative complications between the two groups (p = 0.10). In patients with follow up, 86.7% of (n = 13) patients had documented salivary flow through the natural papilla after one layer closure compared to 80% (n = 4) in the two-layer group. There was no significant difference between the groups (p = 0.72).</p><p><strong>Conclusions: </strong>The results of this study support that single layer closure without ductoplasty after hybrid sialendoscopy allows for ductal recanalization and may produce the same postoperative outcomes as traditional two-layer closure while increasing operative efficiency.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of 5% and 10% povidone-iodine antiseptic concentrations on postoperative sensorineural hearing loss in tympanoplasty: a triple-blind randomized clinical trial.","authors":"Mohammad Faramarzi, Ali Faramarzi, Sareh Roosta, Mahmoud Shishegar, Mohammadreza Khademalizadeh, Sara S Nabavizadeh, Amir Keyvan Sazgar","doi":"10.1007/s00405-025-09310-2","DOIUrl":"https://doi.org/10.1007/s00405-025-09310-2","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the ototoxicity of povidone iodine (PVP-I) at concentrations of 5% and 10% during tympanoplasty by assessing frequency-specific audiometric outcomes and graft success rates in a large cohort of patients.</p><p><strong>Methods: </strong>This prospective, triple-blinded, randomized clinical trial enrolled 542 patients undergoing primary tympanoplasty. After excluding patients for inadequate follow-up, 204 ears received 10% PVP-I and 199 ears received 5% PVP-I. Audiometric evaluations, including bone conduction (BC), air conduction (AC), air-bone gap (ABG), and speech reception threshold (SRT), were conducted preoperatively and 12 months postoperatively. The primary outcome was the incidence of sensorineural hearing loss (SNHL), defined as an increase in BC threshold of more than 10 dB. Secondary outcomes included graft success rate and audiometric gains.</p><p><strong>Results: </strong>The overall incidence of SNHL was 1.5% in the 10% PVP-I group and 1.0% in the 5% PVP-I group, with no significant difference (P = 1.000). In ears with preoperative mixed hearing loss, SNHL at 0.25 kHz was significantly higher in the 10% PVP-I group (28.9%) compared to the 5% PVP-I group (6.7%) (P = 0.002). Graft success rates were 94.1% and 97.0% in the 10% and 5% PVP-I groups, respectively (P = 0.164). No clinically significant differences in audiometric gains were observed between the groups.</p><p><strong>Conclusion: </strong>Both 5% and 10% PVP-I concentrations are safe for antiseptic preparation in tympanoplasty, as evidenced by low rates of SNHL and high graft success rates. These findings support the use of PVP-I in human otologic surgery without significant ototoxic risk.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of inflammatory markers in the diagnosis of complicated rhinosinusitis in children.","authors":"Agah Yeniceri, Melih Cayonu","doi":"10.1007/s00405-025-09278-z","DOIUrl":"https://doi.org/10.1007/s00405-025-09278-z","url":null,"abstract":"<p><strong>Purpose: </strong>Acute rhinosinusitis (ARS) is a common pediatric disorder. When complications occur, it can lead to various morbidities. Therefore, easily accessible and inexpensive markers are needed to predict the development of complications, treatment, and clinical course of acute rhinosinusitis. We aimed to investigate the predictive ability of the various inflammatory markers in pediatric complicated ARS patients.</p><p><strong>Methods: </strong>The data of 79 pediatric patients with complicated ARS and 116 pediatric patients with uncomplicated ARS were analyzed retrospectively. The complete blood count and C-reactive protein (CRP) test results at the time of diagnosis were recorded. Also, a receiver operating characteristic (ROC) analysis was performed.</p><p><strong>Results: </strong>The complicated ARS group consisted of 65 (82.3%) patients with preseptal cellulitis, 4 (5.1%) with orbital cellulitis, 5 (6.3%) with subperiosteal abscess, and 5 (6.3%) with orbital abscess complications. At the time of initial diagnosis, there was a significant difference in WBC, NLR, CRP, %LUC, SII and SIRI values between complicated ARS and uncomplicated ARS patient groups (p < 0.05). In terms of predictive power, the area under the curve (AUC) was 0.805 (95% confidence interval (CI) 0.74-0.87, p < 0.001) for CRP, 0.62 (95% confidence interval (CI) 0.54-0.7, p = 0.004) for systemic immune-inflammatory index (SII) and 0.67 (95% confidence interval (CI) 0.6-0.75, p < 0.001) for systemic inflammatory response index (SIRI).</p><p><strong>Conclusion: </strong>In conclusion, our study shows that inflammatory markers can be helpful in the evaluation of pediatric rhinosinusitis patients. CRP, SII and SIRI were adequate markers of inflammation to predict the development of complications in patients with pediatric rhinosinusitis.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First experience with VITOM eagle in micro-laryngeal surgery on 3D-printed laryngeal models: important improvements in exoscopic technology.","authors":"E Errico, S Mauramati, G Bertino, E Robiolio, M V Veneroni, M Benazzo, R Gelli","doi":"10.1007/s00405-025-09293-0","DOIUrl":"https://doi.org/10.1007/s00405-025-09293-0","url":null,"abstract":"<p><strong>Purpose: </strong>The Karl Storz Company recently introduced a new exoscopic system equipped with new features and improvements compared to older counterparts. The endpoints of this study are to evaluate the new VITOM^® Eagle system and compare it to the older VITOM^® 3D for micro-laryngeal surgery, to analyze the new features of the latest Karl Storz's product and determine whether these upgrades provide a significant advantage to surgery of the laryngeal district.</p><p><strong>Methods: </strong>Participants simulated CO₂ Transoral Laser Microsurgery (CO₂ TOLMS) procedures on 3D-printed laryngeal models firstly with both the VITOM^® 3D and VITOM^® Eagle. At the end of both sessions 2 questionnaires were administered: the first generic 3-item questionnaire comparing evaluating exoscopic and microscopic technology, the second questionnaire involved 8 items related to device quality.</p><p><strong>Results: </strong>Overall the new VITOM^® Eagle resulted superior to the older VITOM^® 3D, there were statistically significant differences in scores evaluating the image quality (p = 0.002), magnification rate (p = 0.002), and luminance (p = 0.047). In addition, according to questionnaires results, senior Otolaryngologists appeared to be slightly less inclined to a complete transition to exoscopy when compared to young surgeons.</p><p><strong>Conclusions: </strong>The results of this study demonstrate how the new VITOM^® Eagle significantly outperforms the older VITOM^® 3D. The upgrades discussed, have the potential of leading to better surgical outcomes by providing surgeons with better tools to navigate complex anatomical districts. Furthermore, results from this study highlighted how exoscopy is affecting the surgical training of young surgeons.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Submandibular sialolithiasis treatment: a comparative pilot prospective study of holmium: YAG laser and pneumatic lithotripsy techniques.","authors":"Necdet Özçelik, Husam Vehbi, Elvin Alaskarov","doi":"10.1007/s00405-025-09309-9","DOIUrl":"https://doi.org/10.1007/s00405-025-09309-9","url":null,"abstract":"<p><strong>Objective: </strong>Sialendoscopy is a minimally invasive technique employed to diagnose and treat obstructions in the major salivary glands.Holmium: YAG Laser Lithotripsy (HLL) and Intraductal Pneumatic Lithotripsy (IPL) are increasingly utilized for stone fragmentation; however, comparative studies are still limited. This study aims to prospectively compare the outcomes of HLL and IPL in cases of submandibular sialolithiasis.</p><p><strong>Materials and methods: </strong>Fifty patients diagnosed with submandibular sialolithiasis were randomly assigned to two groups for treatment with either HLL or IPL. Demographics, stone size and location, operative times, and complications were meticulously documented. Preoperative imaging with ultrasound and computed tomography identified stone parameters. Follow-up assessments occurred at 1 week, 3 months, and 6 months post-treatment, which included a 3-month ultrasound to evaluate for residual stones and assess ductal evaluation.</p><p><strong>Results: </strong>No significant differences between the groups concerning demographics, stone size, or location (p > 0.05). However, the IPL group demonstrated shorter operative times for distal and mid-duct stones (p < 0.05). The stone-free rates were 92% in the HLL group and 96% in the IPL group. The HLL group exhibited higher rates of mucosal laceration and ductal perforation, while the IPL group showed a greater potential for stone migration. Postoperative symptom resolution was achieved in both groups. Additionally, quality of life (QOL) scores, assessed using the SF-36 questionnaire, showed significant improvement at 6 months postoperatively in both groups, with no statistically significant differences between them.</p><p><strong>Conclusion: </strong>Both HLL and IPL are effective treatments for submandibular sialolithiasis. IPL is associated with shorter operative times, especially for distal and mid-duct stones, while the complication rates for both methods remain within acceptable limits.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}