Magdalena Ostrowska, Paulina Kacała, Deborah Onolememen, Katie Vaughan-Lane, Anitta Sisily Joseph, Adam Ostrowski, Wioletta Pietruszewska, Jacek Banaszewski, Maciej J Wróbel
{"title":"To trust or not to trust: evaluating the reliability and safety of AI responses to laryngeal cancer queries.","authors":"Magdalena Ostrowska, Paulina Kacała, Deborah Onolememen, Katie Vaughan-Lane, Anitta Sisily Joseph, Adam Ostrowski, Wioletta Pietruszewska, Jacek Banaszewski, Maciej J Wróbel","doi":"10.1007/s00405-024-08643-8","DOIUrl":"10.1007/s00405-024-08643-8","url":null,"abstract":"<p><strong>Purpose: </strong>As online health information-seeking surges, concerns mount over the quality and safety of accessible content, potentially leading to patient harm through misinformation. On one hand, the emergence of Artificial Intelligence (AI) in healthcare could prevent it; on the other hand, questions raise regarding the quality and safety of the medical information provided. As laryngeal cancer is a prevalent head and neck malignancy, this study aims to evaluate the utility and safety of three large language models (LLMs) as sources of patient information about laryngeal cancer.</p><p><strong>Methods: </strong>A cross-sectional study was conducted using three LLMs (ChatGPT 3.5, ChatGPT 4.0, and Bard). A questionnaire comprising 36 inquiries about laryngeal cancer was categorised into diagnosis (11 questions), treatment (9 questions), novelties and upcoming treatments (4 questions), controversies (8 questions), and sources of information (4 questions). The population of reviewers consisted of 3 groups, including ENT specialists, junior physicians, and non-medicals, who graded the responses. Each physician evaluated each question twice for each model, while non-medicals only once. Everyone was blinded to the model type, and the question order was shuffled. Outcome evaluations were based on a safety score (1-3) and a Global Quality Score (GQS, 1-5). Results were compared between LLMs. The study included iterative assessments and statistical validations.</p><p><strong>Results: </strong>Analysis revealed that ChatGPT 3.5 scored highest in both safety (mean: 2.70) and GQS (mean: 3.95). ChatGPT 4.0 and Bard had lower safety scores of 2.56 and 2.42, respectively, with corresponding quality scores of 3.65 and 3.38. Inter-rater reliability was consistent, with less than 3% discrepancy. About 4.2% of responses fell into the lowest safety category (1), particularly in the novelty category. Non-medical reviewers' quality assessments correlated moderately (r = 0.67) with response length.</p><p><strong>Conclusions: </strong>LLMs can be valuable resources for patients seeking information on laryngeal cancer. ChatGPT 3.5 provided the most reliable and safe responses among the models evaluated.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11512842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Repositioning chair treatment procedure for cupulolithiasis: case report (with video).","authors":"Quentin Legois, Charles-Edouard Molinier, Pauline Nieto, Mathieu Marx","doi":"10.1007/s00405-024-08807-6","DOIUrl":"10.1007/s00405-024-08807-6","url":null,"abstract":"<p><strong>Introduction: </strong>A cupulolithiasis of the lateral semicircular canal is an accumulation of otolithic debris at the level of the cupula of the same canal. Its pathophysiology generally generates a specific clinical presentation. This situation can be very disabling for the patient and tricky to treat for the clinician.</p><p><strong>Case report: </strong>The patient was a 70-year-old man with cupulolithiasis of the right lateral semicircular canal. We present here the conversion of cupulolithiasis to canalolithiasis using the Thomas Richard Vitton (TRV) repositioning chair, as well as the treatment of this canalolithiasis through a mechanical liberation maneuver.</p><p><strong>Conclusion: </strong>The results of manual therapeutic maneuvers for Benign Paroxysmal Positional Vertigo (BPPV) are generally good regardless of the type of BPPV. It can sometimes be more challenging to resolve an ageotropic-type BPPV of the lateral semicircular canal and mechanically-assisted maneuvers using a repositioning chair may be required. Faced with symptom resistance despite attempts at multiple liberatory maneuvers, clinicians must be able to reconsider their initial diagnosis and investigate other potentially more serious origins of these symptoms. The TRV chair can be a treatment option in the management of cupulolithiasis, especially in cases where classic reduction maneuvers do not always yield good results.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11512914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141603471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmad Muhammad Al-Arman, Waleed Moneir, Hazem Emam Amer, Hisham Atef Ebada
{"title":"Platelet rich fibrin augmented tympanoplasty versus cartilage tympanoplasty: a randomized clinical trial.","authors":"Ahmad Muhammad Al-Arman, Waleed Moneir, Hazem Emam Amer, Hisham Atef Ebada","doi":"10.1007/s00405-024-08819-2","DOIUrl":"10.1007/s00405-024-08819-2","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the current study was to evaluate the efficacy of PRF-augmented fascia tympanoplasty versus cartilage tympanoplasty in repair of large TM perforations.</p><p><strong>Methods: </strong>This randomized clinical trial included 156 patients with dry large tympanic membrane perforations. Patients were randomly allocated into 2 groups, cartilage tympanoplasty group (n = 77) and platelet rich fibrin (PRF) augmented tympanoplasty group (n = 79). Graft take rates, hearing outcomes, operative time, and postoperative complications were documented and compared.</p><p><strong>Results: </strong>Graft take rate was 96.1% in the cartilage group and 93.7% PRF group with no statistically significant difference. Operative time was significantly longer in the cartilage group. No differences in the hearing outcomes and postoperative complications were reported.</p><p><strong>Conclusion: </strong>Application of PRF on the fascia in tympanoplasty promotes healing of the tympanic membrane. PRF is safe, cheap, readily available, and easily prepared and applied. It increases the success rates of large tympanic membrane perforations without the need for cartilage grafts.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11512834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dzemal Gazibegovic, Andrea Bohnert, Anne Katrin Laessig
{"title":"Hearing Aid apps: are they safe, practical and beneficial for children and teens in challenging situations?","authors":"Dzemal Gazibegovic, Andrea Bohnert, Anne Katrin Laessig","doi":"10.1007/s00405-024-08851-2","DOIUrl":"10.1007/s00405-024-08851-2","url":null,"abstract":"<p><strong>Purpose: </strong>An adult version of an app giving users the control over the level of the volume, microphone directionality and noise reduction was adapted for children. The main purpose of this study was to evaluate the effect of changes made to microphone directionality and noise reduction in the myPhonak Junior (the app) on Speech intelligibility in challenging listening environments in children and teens.</p><p><strong>Methods: </strong>The randomized, non-blinded interventional study with a single group of subjects involved two study visits with a home trial in-between. In the final study session speech assessment in noise was conducted in three different, randomly assigned conditions: default mode (Autosense Sky OS), preffered (self-adjusted) and the extreme condition. Questionnaire based assessment was conducted to assess the subjective benefit of using the app in different daily situations.</p><p><strong>Results: </strong>The best scores (speech results in noise) were achieved with the preferred setting and the default Autosense Sky OS setting was significantly better than the extreme setting. The self-reported benefit through the questionnaire indicates significantly better result when adjusting the hearing aids through the app.</p><p><strong>Conclusion: </strong>The app is an easy-to-use way of controlling the level of noise reduction and the beam forming for children 11 years and older. It has the potential to help customizing the hearing aids beyond the default setting and helping to improve speech understanding in noise.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11512926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ariel Roitman, Anumitha Venkatraman, Susan Thibeault
{"title":"Predictors of injection laryngoplasty volume for glottic insufficiency.","authors":"Ariel Roitman, Anumitha Venkatraman, Susan Thibeault","doi":"10.1007/s00405-024-08908-2","DOIUrl":"10.1007/s00405-024-08908-2","url":null,"abstract":"<p><strong>Purpose: </strong>Volume injected for glottic insufficiency is paramount in achieving desired outcome. Factors that determine the required volume have not been thoroughly investigated and may correlate with outcome. The first objective of this investigation was to evaluate the association between injectable volume and various parameters, including lifestyle characteristics, pre-procedural factors, and voice measures, while the second aim assessed the correlation of volume to clinical outcomes in patients who underwent injection laryngoplasty.</p><p><strong>Methods: </strong>For the first objective, a one-way ANOVA and univariate linear regression were used to analyze data from 124 patients (injected material, pre-operative diagnosis, previous voice therapy, age etc.). One-sample t-tests and Pearson correlational coefficients were employed for statistical analysis of aim 2 in a subgroup of 28 patients that had pre- and post-injection voice evaluations (e.g., acoustic and aerodynamic analysis, perceptual assessment, questionnaires).</p><p><strong>Results: </strong>Average injection volume was 0.39 ± 0.062 mL (range: 0.1-1.6mL). No pre-procedural or lifestyle factor significantly affected injection volume (p > 0.05). There was no relationship between pre-procedural voice outcomes and injection volume (p > 0.05). Of the factors that were significantly improved post-injection laryngoplasty (GFI, VHI, and GRBAS), there were no significant correlations between the magnitude of improvement in these measures and injection volume (p > 0.05).</p><p><strong>Conclusion: </strong>Injection volume does not appear to be affected by pre-procedural or lifestyle factors. In addition, injection volume does not significantly impact clinical outcomes assessed through voice analysis or patient-reported questionnaires. Our results underscore the complexity of factors at play in injection laryngoplasty for glottic insufficiency.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11512904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trends and projections of mild and moderate hearing loss among adolescents, young adults, middle-aged adults and age-standardised population in Malaysia from 1996 to 2030.","authors":"Najihah Lokman, Wan Nur Asyiqin Rasidi","doi":"10.1007/s00405-024-08796-6","DOIUrl":"10.1007/s00405-024-08796-6","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to assess the prevalence of mild and moderate hearing loss spanning three decades, from 1990 to 2019, and to project the anticipated trends from 2020 to 2030 among adolescents, young adults, middle-aged adults, and age-standardised groups in Malaysia.</p><p><strong>Methods: </strong>This study involved secondary data analysis of mild and moderate hearing loss prevalence over 30 years among the Malaysian population aged 15-19, 25-29, 35-39, 45-49, and age-standardised groups. Subsequently, three time-series models were evaluated and the best models with the minimal Mean Absolute Percentage Error (MAPE) and Root Mean Squared Error (RMSE) were selected for projecting the prevalence of hearing loss until 2030.</p><p><strong>Results: </strong>A relatively stable trend of mild hearing loss prevalence and gradual decline of moderate hearing loss were observed across all age groups throughout the study period. The prevalence of mild hearing loss was consistently higher than moderate hearing loss across all age groups, with its prevalence increasing with age. The projected prevalence of hearing loss exhibits a gradual declining trend in the future for all age groups, except for mild hearing loss for the 15-19-year-old group.</p><p><strong>Conclusion: </strong>Over the past 30 years, there has been a relatively stable and slightly declining trend in the prevalence of mild and moderate hearing loss among the Malaysian population, respectively with projections showing a slow reduction in the future. These findings highlighted the need for identifying the best intervention and vulnerable age groups, directing increased resources and prioritization towards them.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new surgical technique to increase airflow in the olfactory cleft: superior turbinate lateralization procedure.","authors":"Teru Ebihara, Kazuhiro Omura, Hironobu Nishijima, Takahisa Yamamoto, Nobuyoshi Otori, Shu Kikuta","doi":"10.1007/s00405-024-08848-x","DOIUrl":"10.1007/s00405-024-08848-x","url":null,"abstract":"<p><strong>Background: </strong>The olfactory cleft (OC) is the most important anatomical site for the maintenance of olfactory function. Obstruction of airflow in the OC by various conditions, such as inflammation, leads to poor olfactory function. Therefore, it is important to increase OC airflow while performing endoscopic sinus surgery (ESS). However, no technique to increase airflow has yet been established.</p><p><strong>Methods: </strong>We designed a superior turbinate lateralization (STL) procedure that displaces the entire ST bone laterally by eliminating the connection between the posterior ST and the anterior wall of the sphenoid sinus. The effect of the STL procedure was investigated in terms of anatomy and olfactory function.</p><p><strong>Results: </strong>ESS with the STL procedure was performed on seven patients with chronic rhinosinusitis and nasal polyps. The cross-sectional area of the OC at 3 months postoperatively was significantly larger than that before ESS. In addition, the Open Essence test and questionnaires revealed significantly improvements in sense of smell. Airflow in the OC was significantly higher in STL procedure group than in the non-STL procedure group.</p><p><strong>Conclusion: </strong>The STL procedure enlarges the bony framework of the OC, and by increasing OC airflow, facilitates the transport of odorants to the olfactory epithelium, thereby improving olfactory perception.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Difference in the immediate effect on positional nystagmus for head positions with interval time during Epley maneuver: a randomized trial.","authors":"Takao Imai, Kayoko Higashi-Shingai, Yuya Ueno, Yumi Ohta, Takashi Sato, Takefumi Kamakura, Tomoko Iga, Shinji Mikami, Naomiki Kimura, Takashi Nakajima, Hiroto Fujita, Hidenori Inohara","doi":"10.1007/s00405-024-08831-6","DOIUrl":"10.1007/s00405-024-08831-6","url":null,"abstract":"<p><strong>Objectives: </strong>The Epley maneuver (EM) shows immediate effect, wherein disappearance of positional nystagmus occurs soon after the EM. Our previous study showed that setting interval times during the EM reduced the immediate effect. The purpose of this study is to identify the head position for which interval time reduces the immediate effect.</p><p><strong>Methods: </strong>Fifty-one patients with posterior canal type of benign paroxysmal positional vertigo (BPPV) were randomly assigned to the following three groups: 10 min interval time set at the first head position of the EM in group A, at the third head position in group B, and at the fourth head position in group C. The primary outcome measure (POM) was the ratio of maximum slow-phase eye velocity of positional nystagmus soon after the EM, compared with that measured before the EM. A large ratio value indicates a poor immediate effect of the EM.</p><p><strong>Results: </strong>The POM in group A (0.07) was smallest (B: 0.36, C: 0.49) (p < 0.001).</p><p><strong>Discussion: </strong>The interval times at the third and fourth head positions reduced the immediate effect of the EM. Our previous study showed that the effect of BPPV fatigue is continued by maintaining the first head position of the EM. BPPV fatigue constitutes fatigability of positional nystagmus with repeated performance of the Dix-Hallpike test. Our findings may be interpreted in accordance with the theory that the immediate effect of the EM is BPPV fatigue itself, because we observed that the effect of BPPV fatigue is strongest in group A.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sevgi Kutlu, Zehra Aydogan, Banu Baş, Cem Meço, Suna Tokgoz-Yilmaz
{"title":"Interaction of sensory processing and balance in adult cochlear implant users.","authors":"Sevgi Kutlu, Zehra Aydogan, Banu Baş, Cem Meço, Suna Tokgoz-Yilmaz","doi":"10.1007/s00405-024-08776-w","DOIUrl":"10.1007/s00405-024-08776-w","url":null,"abstract":"<p><strong>Puropse: </strong>The aim of this study was to evaluate the sensory processing skills, quality of life and balance performance in adult cochlear implant users.</p><p><strong>Methods: </strong>A sample of 40 individuals was studied in two groups; 20 normal hearing individuals (37.84 ± 15.39 years old) and 20 cochlear implant users (35.58 ± 11.22 year old). Balance performance was assessed by Computerized Dynamic Posturography. The Adolescent/Adult Sensory Profile completed by the individual was used to assess sensory processing skills. Finally, quality of life was assessed with the Short Form-36.</p><p><strong>Results: </strong>Among the different sensory processing parameters in the adolescent/adult sensory profile, a significant difference was found between the two groups in the parameters of low registration, sensory sensitivity and sensory avoidance (p < .05). Visual, vestibular and composite scores were found to be lower in cochlear implant users by Computerised Dynamic Posturography assessment (p < .05). When assessing quality of life, emotional well-being and social functioning parameters were found to be lower in cochlear implant users (p < .05).</p><p><strong>Conclusion: </strong>Factors such as the inability to reach sufficient auditory stimuli due to hearing loss and the occurrence of vestibular problems after cochlear implant surgery limit the quantity and quality of sensory stimuli from the environment. Individuals with cochlear implants may prefer to live isolated from society because they cannot adequately process incoming sensory stimuli due to hearing/balance problems, and this may negatively affect the quality of life of individuals. Our findings revealed the necessity of multisensory assessment and therapy protocols when rehabilitating individuals with cochlear implants.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11512880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shubin Li, Anne Wolter, Christine Kelly, Barry Smith, Katie Whitcroft, Harry Sherwood, Beth Longley, Thomas Hummel
{"title":"A novel olfactory sorting task.","authors":"Shubin Li, Anne Wolter, Christine Kelly, Barry Smith, Katie Whitcroft, Harry Sherwood, Beth Longley, Thomas Hummel","doi":"10.1007/s00405-024-08811-w","DOIUrl":"10.1007/s00405-024-08811-w","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to develop a simple self-administered screening tool for odor memory, which allowed users to self-test their olfactory function repeatedly even at home.</p><p><strong>Methods: </strong>One hundred and ten participants were recruited (30 men, age = 50.1 ± 9.9 years; 80 women, age = 47.1 ± 11.5 years); half of them were heathy volunteers, the other half were patients with olfactory dysfunction. Fifty-one healthy participants volunteered for a retest within an interval of a maximum of 14 days. Olfactory function was assessed using the extended Sniffin' Sticks test (SST) comprising tests for odor threshold, identification, and discrimination. All participants received the Novel Olfactory Sorting Task (NOST) which is based on the sorting of 12 matching pairs of odors involving olfactory and cognitive functions. After that, all participants rated questions related to their test performance and the practicability of the test.</p><p><strong>Results: </strong>Consistent with the previous literature, significant effects of age were found. Results showed an acceptable test-retest reliability and a satisfactory validity of the NOST. The NOST score not only had positive correlations with SST, but also was capable of differentiating severe hyposmia/anosmia from normosmia by the score of 5.5 (sensitivity of 76.2%, specificity of 77.6%).</p><p><strong>Conclusion: </strong>The present study showed the good reliability, validity, and possible clinical usefulness of the NOST. As a self-performed screening test, it can be comprehended and conducted easily, which may provide a quick and simple approach to obtaining a global estimation of olfactory and cognitive functions.</p>","PeriodicalId":11952,"journal":{"name":"European Archives of Oto-Rhino-Laryngology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11512826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141603450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}