European Journal of Clinical Nutrition最新文献_第2页

It is preemptive to question recommendations to limit ultra-processed foods. 对限制超加工食品的建议提出质疑是先发制人的。

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2025-03-27 DOI: 10.1038/s41430-025-01606-0

Shae-Leigh Vella, Nagesh Pai

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Association of meal time patterns with dietary intake and body mass index: a chrononutrition approach from NHANES 2017-2018. 用餐时间模式与膳食摄入量和体重指数的关联：NHANES 2017-2018的时间营养方法。

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2025-03-26 DOI: 10.1038/s41430-025-01603-3

Gabriela Pereira Teixeira, Nayara Bernardes da Cunha, Catarina Machado Azeredo, Ana Elisa Madalena Rinaldi, Cibele Aparecida Crispim

{"title":"Association of meal time patterns with dietary intake and body mass index: a chrononutrition approach from NHANES 2017-2018.","authors":"Gabriela Pereira Teixeira, Nayara Bernardes da Cunha, Catarina Machado Azeredo, Ana Elisa Madalena Rinaldi, Cibele Aparecida Crispim","doi":"10.1038/s41430-025-01603-3","DOIUrl":"https://doi.org/10.1038/s41430-025-01603-3","url":null,"abstract":"Background: Chrononutrition studies suggest that eating later and extending the eating window are linked to higher energy intake and obesity. However, the relationship between chrononutrition variables and dietary intake, as well as with BMI, is still little explored at a population level. This study explored how chrononutrition variables relate to dietary intake and BMI at a population level.Methods: We analyzed data from the NHANES 2017-2018, including 2937 participants aged 18 years or older. Dietary intake was assessed by two 24-h dietary recalls. Caloric midpoint, eating window duration, sleep end-first meal and last meal-sleep onset intervals were determined by mealtime.Results: The findings indicate a trend of increased total consumption of energy (kcal) (p < 0.001; p < 0.001; p < 0.001; p < 0.001), carbohydrates (g) (p = 0.001; p < 0.001; p < 0.001; p < 0.001); protein (g) (p < 0.001; p = 0.008; p < 0.001; p < 0.001), fat (g) (p < 0.001; p = 0.007; p < 0.001; p < 0.001), and sugar (g) (p < 0.001; p < 0.001; p < 0.001; p < 0.001) as the sleep end-first meal interval decreases and the last meal-sleep onset interval, eating window, and energy intake after 8 pm increases, respectively. In addition, our findings suggest a trend of increased BMI in the group with BMI ≥ 30 kg/m² (p = 0.018) as sleep end-first meal interval increases and in the group with BMI < 25 kg/m² (p = 0.006) as the eating window increases.Conclusion: Our findings suggest that eating later and having longer eating window are associated with higher dietary intake and higher BMI.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Reply to Vella and Pai. 回复维拉和派。

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2025-03-25 DOI: 10.1038/s41430-025-01607-z

Francesco Visioli, Daniele Del Rio, Vincenzo Fogliano, Franca Marangoni, Cristian Ricci, Andrea Poli

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A systematic review of the impact of Elexacaftor/Tezacaftor/Ivacaftor on body composition in people with cystic fibrosis. elexaftor /Tezacaftor/Ivacaftor对囊性纤维化患者体成分影响的系统综述

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2025-03-22 DOI: 10.1038/s41430-025-01589-y

Laura Kinsey, Hannah Winterbottom, Lydia Hudson, Simon Lal, Andrew M Jones, Sorrel Burden

{"title":"A systematic review of the impact of Elexacaftor/Tezacaftor/Ivacaftor on body composition in people with cystic fibrosis.","authors":"Laura Kinsey, Hannah Winterbottom, Lydia Hudson, Simon Lal, Andrew M Jones, Sorrel Burden","doi":"10.1038/s41430-025-01589-y","DOIUrl":"10.1038/s41430-025-01589-y","url":null,"abstract":"Elexacaftor/Tezacaftor/Ivacaftor (ETI) has led to improved lung function, life expectancy, and body mass index for people with Cystic Fibrosis (CF). The aim of this systematic review was to evaluate the impact that ETI has had on body composition in people with CF. A systematic review was performed using MEDLINE, EMBASE, CINAHL, and the Cochrane Central Register of Controlled Trials. Quality assessment using the Joanna Briggs Institute critical appraisal tools were performed. Results were summarised narratively. Five observational cohort studies involving a total of 185 participants were reviewed. Three studies showed an increase in fat mass (7.0-8.6 kg, 13.2-14.3 kg, and 13.4-15.5 kg). Two studies reported an increase in fat-free mass (49.4-50.1 kg, 52.5-55 kg), while one reported a decrease (50.5-48.9 kg). Two studies found an increase in fat mass index (4.1-6.3 kgm/2 and 4.7-5.4 kg/m2) and fat-free mass index (17.4-17.7 kg/m2 and 18.1-18.8 kg/m2). Two studies observed an increase in percentage body fat mass (12.1-15.4% and 23.1-27.6%). Four studies were classified as low quality, while one was considered medium quality. This review suggest that commencing ETI results in changes in body composition. Firm conclusions about the type and distribution of change in body composition cannot be made due to limited studies, high heterogeneity, and methodical weaknesses. It highlights the necessity for higher quality and longer-term studies to explore the impact that ETI is having on body composition.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Food additives containing potassium, phosphorus, and sodium in ultra-processed foods: potential harms to individuals with chronic kidney disease. 超加工食品中含有钾、磷和钠的食品添加剂：对慢性肾病患者的潜在危害

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2025-03-21 DOI: 10.1038/s41430-025-01600-6

Valeria Cecchini, Alice Sabatino, Barbara Contzen, Carla Maria Avesani

引用次数: 0

Modified cornstarch as an effective treatment for insulinoma-induced hypoglycemia: a case report. 改性玉米淀粉对胰岛素瘤性低血糖的有效治疗：1例报告。

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2025-03-21 DOI: 10.1038/s41430-025-01595-0

Karen Castillo, Aida Orois, Diego Duminy-Luppi, Clara Viñals, Daria Roca, Cristina Montserrat-Carbonell, Betina Campero, Amanda Jiménez, Ana Matas, Jesús Aibar, Mireia Mora, Felicia A Hanzu, Adriana Pané

{"title":"Modified cornstarch as an effective treatment for insulinoma-induced hypoglycemia: a case report.","authors":"Karen Castillo, Aida Orois, Diego Duminy-Luppi, Clara Viñals, Daria Roca, Cristina Montserrat-Carbonell, Betina Campero, Amanda Jiménez, Ana Matas, Jesús Aibar, Mireia Mora, Felicia A Hanzu, Adriana Pané","doi":"10.1038/s41430-025-01595-0","DOIUrl":"https://doi.org/10.1038/s41430-025-01595-0","url":null,"abstract":"A 90-year-old male was admitted to the hospital due to recurrent symptomatic hypoglycemia. After ruling out the most common outpatient causes of hypoglycemia, endogenous hyperinsulinism was confirmed. An abdominal computed tomography (CT) scan revealed a 15 mm solid nodular lesion in the pancreatic tail. The (68)Ga-DOTA-TOC PET-CT findings led to the diagnosis of insulinoma. A multidisciplinary committee considered the patient unfit for surgery. The treatment was started with a low dose of diazoxide; however, side effects appeared as the dose was gradually increased. Consequently, a dietary approach was prioritized, incorporating modified cornstarch (Glycosade®) in fractionated doses administered under the guidance of continuous glucose monitoring. This strategy allowed for a reduction in the diazoxide dosage and effectively prevented further hypoglycemic episodes without additional side effects. Since the initial medical treatment was successful, the patient and his family preferred to avoid other possible minimally invasive treatments unless pharmacological and dietary approaches failed.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel comparative analysis and equation development for body volume estimation using dual-energy x-ray absorptiometry in athletes. 利用双能x射线吸收仪估算运动员体体积的新型对比分析和方程开发。

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2025-03-21 DOI: 10.1038/s41430-025-01594-1

Tiago R Silva, Filipe Jesus, Rui Poínhos, Luís B Sardinha, Vitor Hugo Teixeira, Steven B Heymsfield, Analiza M Silva

{"title":"Novel comparative analysis and equation development for body volume estimation using dual-energy x-ray absorptiometry in athletes.","authors":"Tiago R Silva, Filipe Jesus, Rui Poínhos, Luís B Sardinha, Vitor Hugo Teixeira, Steven B Heymsfield, Analiza M Silva","doi":"10.1038/s41430-025-01594-1","DOIUrl":"https://doi.org/10.1038/s41430-025-01594-1","url":null,"abstract":"Background/objectives: Dual-energy x-ray absorptiometry (DXA) has been suggested as an alternative method for estimating body volume (BV), a component of the reference four-compartment body composition model. This study reports the development and validation of DXA-BVSilva, a novel DXA-derived BV equation. An additional aim was to develop an estimate of lean soft tissue density (DLST), a key variable in the theory-based approach, by estimating total body protein with a six-compartment model.Methods: A sample of 332 athletes (36.7% females) from several sports were randomly assigned to either the development (n = 232) or cross-validation group (n = 100). DXA-BVSilva was developed via linear regression of DXA-measured fat, lean soft tissue, and bone mineral mass against BV measured with air displacement plethysmography (ADP). A DLST estimate of 1.064 kg/L (SD = 0.006) was obtained from a subset of the development sample comprising 201 athletes (36.3% females) with available measurements of total-body water by deuterium dilution, bone mineral by DXA and BV by ADP, enabling total-body protein determination from a six-compartment model.Results: DXA-BVSilva provided the closest BV estimation (mean difference = 0.05 L, SD = 0.46 L; ES [95% CI] = 0.11 [-0.08; 0.31]) and the 95% limits of agreement (-0.86 to 0.96 L) were narrower than existing empirical equations.Conclusion: We conducted the first comparative analysis of both empirical and theoretical BV estimation methods using DXA, demonstrating the validity of DXA-BVSilva for BV estimation in athletes, presenting a robust alternative to ADP, with potential applications in multicomponent body composition models.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of CYP2R1 and GC gene polymorphisms on serum 25(OH)D response to vitamin D₃ supplementation in prediabetes. CYP2R1和GC基因多态性对糖尿病前期补充维生素D3后血清25(OH)D反应的影响

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2025-03-20 DOI: 10.1038/s41430-024-01564-z

Peng Ni, Ze Xu, Yujing Zhang, Dongdong Zhang, Hongwei Wen, Yaping Liu, Wenjie Li, Xing Li

{"title":"Effect of CYP2R1 and GC gene polymorphisms on serum 25(OH)D response to vitamin D3 supplementation in prediabetes.","authors":"Peng Ni, Ze Xu, Yujing Zhang, Dongdong Zhang, Hongwei Wen, Yaping Liu, Wenjie Li, Xing Li","doi":"10.1038/s41430-024-01564-z","DOIUrl":"https://doi.org/10.1038/s41430-024-01564-z","url":null,"abstract":"Background: Prediabetes is a crucial period for preventing and managing diabetes. This study aimed to explore the effects of CYP2R1/GC gene polymorphisms on vitamin D3 supplementation responsiveness in prediabetes.Methods: A total of 240 prediabetic participants received orally 1600 IU of vitamin D3 or placebo daily for 24 weeks.Results: CYP2R1 rs12794714 AA carriers had less increased 25(OH)D3 levels compared with GG carriers after supplementation (3.42 (0.05, 6.79) vs. 8.49 (6.14, 10.83), P = 0.038). Moreover, GC rs4588 GA carriers had less increased 25(OH)D3 levels compared with GG carriers (4.71 (2.64, 6.79) vs. 8.17 (6.37, 9.98), P = 0.033); it also had lower supplementation responsiveness (0.35 (0.14, 0.91), P = 0.032). GC rs4752 AG carriers had higher supplementation responsiveness compared with AA carriers (3.48 (1.05, 11.59), P = 0.042).Conclusions: The results indicated that CYP2R1 rs12794714, GC rs4588, and GC rs4752 polymorphism were associated with vitamin D3 supplementation responsiveness in prediabetes.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diet intake and adherence to recommendations in women with gestational diabetes mellitus. 妊娠期糖尿病妇女的饮食摄入和依从性。

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2025-03-19 DOI: 10.1038/s41430-025-01596-z

Lotta Saros, Tero Vahlberg, Outi Pellonperä, Kristiina Tertti, Kirsi Laitinen

{"title":"Diet intake and adherence to recommendations in women with gestational diabetes mellitus.","authors":"Lotta Saros, Tero Vahlberg, Outi Pellonperä, Kristiina Tertti, Kirsi Laitinen","doi":"10.1038/s41430-025-01596-z","DOIUrl":"https://doi.org/10.1038/s41430-025-01596-z","url":null,"abstract":"Background/objectives: Gestational diabetes mellitus (GDM) is best managed via lifestyle changes. We aimed at investigating to which extent women with GDM adhered to dietary recommendations and to which extent an impact was observed on the glycaemic control compared to women without GDM.Subjects/methods: Women with overweight/obesity (n = 349) were recruited in early pregnancy. GDM was diagnosed with a 2-h oral glucose tolerance test in mid-or-early pregnancy (median 25.9 and 14.7 gestational weeks). Dietary assessments included an index of dietary quality (good ≥ 10 and poor < 10/15 scores) and 3-day food-diaries with nutrient intake calculated and dietary patterns identified. Glucose and insulin concentrations were analysed from blood samples collected in late pregnancy (after GDM diagnosis).Results: Women with GDM (n = 98) followed more often a healthier dietary pattern (62.2%) than women without GDM (49.0%, p < 0.05), but no difference in good dietary quality was seen (53% vs. 59.8%, p = 0.071). While the majority of women with GDM adhered to some recommendations, 51% to carbohydrate, 54.1% to total fat and 69.4% to sucrose, only 16.3% adhered to the protein and 4.1% to the fibre intake recommendations. Women with GDM had lower adherence to protein, total fat and fibre recommendations but higher adherence to that of sucrose than women without GDM (p < 0.05). A good dietary quality was associated with lower insulin and HOMA2-IR values (p < 0.05).Conclusions: Adherence to dietary recommendations, particularly fibre and protein intake, is unsatisfactory in women with GDM. Overall dietary quality is related to better control of glucose metabolism proposing a target for dietary counselling.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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The emergence of meal delivery applications: a research agenda to advance the next decade of progress in nutrition. 外卖应用的出现：推动下一个十年营养进展的研究议程。

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2025-03-19 DOI: 10.1038/s41430-025-01597-y

Si Si Jia, Rebecca Bennett, Adyya Gupta

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