European Heart Journal: Case Reports最新文献

{"title":"Right-left discordance of pulmonary artery wedge pressure under high positive end-expiratory pressure in acute eccentric mitral regurgitation.","authors":"Hiroki Mori, Taku Omori, Shiro Nakamori, Kaoru Dohi","doi":"10.1093/ehjcr/ytag720","DOIUrl":"10.1093/ehjcr/ytag720","url":null,"abstract":"","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"10 10","pages":"ytag720"},"PeriodicalIF":0.7,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small but lethal: cystic tumour of the atrioventricular node-a case report.","authors":"Jessica V Yao, Homa Forotan, Geoffrey Lee, William Wilson, Kai En Leong","doi":"10.1093/ehjcr/ytag686","DOIUrl":"10.1093/ehjcr/ytag686","url":null,"abstract":"<p><strong>Background: </strong>Cystic tumours of the AV node (CTAVN) are exceptionally uncommon congenital cardiac tuours, with an incidence of 0.0017-0.03%.</p><p><strong>Case summary: </strong>A 47-year-old woman with recurrent symptomatic tachycardia underwent an ablation. Coronary sinus was noted to be enlarged. Subsequent cardiac CT revelead a well-circumscribed cystic lesioni in the Triangle of Koch, suspicious of a CTAVN. Multimodal imaging, including echocardiography, coronary angiography and cardiac MRI confirmed a non-vascular, encapsulated lesion with imaging characteristics consistent with a benign cystic mass. Given the risk of sudden cardiac death, surgical resection was performed. Histopathology confirmed CTAVN. The postoperative course as complicated by complete heart block requiring pacemaker implantation, with no recurrence at one year.</p><p><strong>Discussion: </strong>CTAVN is a rare but clinically significant benign tumour associated with conduction abnormalities and malignant arrhythmias. This care highlights the importance of multimodal imaging in diagnosis and the role of early surgical intervention to mitigate life-threatening complications.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"10 9","pages":"ytag686"},"PeriodicalIF":0.7,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13623222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149079763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cloverleaf-like lumen configuration in nodular calcification.","authors":"Aninka Saboe, Hector M Garcia-Garcia, Michael Haude, Ron Waksman","doi":"10.1093/ehjcr/ytag719","DOIUrl":"https://doi.org/10.1093/ehjcr/ytag719","url":null,"abstract":"","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"10 10","pages":"ytag719"},"PeriodicalIF":0.7,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13637576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149106015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>TRPM4</i>-related left bundle branch block-induced cardiomyopathy reversed by left bundle branch area pacing-based cardiac resynchronization therapy: a case report.","authors":"Sijin Wu, Xinyue Wang, Bin Zhou, Tong Zou, Xue Yu","doi":"10.1093/ehjcr/ytag718","DOIUrl":"https://doi.org/10.1093/ehjcr/ytag718","url":null,"abstract":"<p><strong>Background: </strong>Progressive cardiac conduction disease (PCCD) is a rare inherited disorder characterized by degeneration of the His-Purkinje system. Although primarily considered an electrical disease, chronic left bundle branch block (LBBB) may result in mechanical dyssynchrony and reversible cardiomyopathy.</p><p><strong>Case summary: </strong>A 59-year-old man presented with progressive left ventricular (LV) dilation and systolic dysfunction. Electrocardiography showed complete LBBB with a QRS duration of 165 ms. Ischaemic and infiltrative cardiomyopathies were ruled out. Cardiac magnetic resonance imaging revealed LV enlargement without late gadolinium enhancement but with marked mechanical dyssynchrony. Genetic testing identified a likely pathogenic <i>TRPM4</i> c.393G>C variant, considered contributory to the conduction phenotype. LBBB-induced cardiomyopathy and heart failure with reduced ejection fraction were diagnosed. The patient underwent left bundle branch area pacing (LBBAP)-based cardiac resynchronization therapy. The QRS duration narrowed to 115 ms, and follow-up echocardiography demonstrated marked reverse remodelling with LV ejection fraction improving from 26% to 48%.</p><p><strong>Discussion: </strong>This case suggests that <i>TRPM4</i>-related PCCD may present with isolated LBBB leading to dyssynchrony-mediated cardiomyopathy. LBBAP can effectively restore electrical synchrony and promote reverse LV remodelling. This favourable response highlights the importance of timely physiological resynchronization in potentially reversible LBBB-related cardiomyopathy.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"10 10","pages":"ytag718"},"PeriodicalIF":0.7,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13695054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149264633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated native pulmonary valve endocarditis on a bicuspid valve with large vegetation and septic pulmonary emboli: a multimodality imaging case report.","authors":"Shabnam Boudagh, Marziyeh Najafi, Mohammad Reza Tolou Ostadan Yazd, Reza Khosravi","doi":"10.1093/ehjcr/ytag687","DOIUrl":"10.1093/ehjcr/ytag687","url":null,"abstract":"<p><strong>Background: </strong>Isolated pulmonary valve endocarditis (PVE) is a rare form of infective endocarditis (IE), accounting for fewer than 2% of all cases. Its presentation often mimics primary respiratory disease, and visualization of the pulmonary valve may be challenging, leading to diagnostic delay. Multimodality imaging is therefore essential for early recognition and treatment planning.</p><p><strong>Case summary: </strong>We report a 59-year-old woman with a history of colorectal cancer treated with surgery and colostomy who presented with 1 month of fever and progressive dyspnoea. Transthoracic and transoesophageal echocardiography demonstrated a bicuspid pulmonary valve with two large, highly mobile vegetations (largest 3.0 × 0.9 cm), mild-to-moderate pulmonary regurgitation, and a small perimembranous ventricular septal defect with left-to-right shunt. Chest computed tomography (CT) showed multiple segmental and subsegmental filling defects compatible with septic pulmonary emboli and signs of right ventricular strain. Blood cultures grew group D viridans streptococci. Despite 6 weeks of targeted intravenous antibiotics, she developed right-sided heart failure with persistent large vegetations. She underwent pulmonary valve replacement with a 27-mm mechanical bileaflet prosthesis and concomitant repair of the ventricular septal defect and closure of the patent foramen ovale. Follow-up imaging confirmed a well-functioning prosthetic valve with improved haemodynamics.</p><p><strong>Discussion: </strong>This case highlights the diagnostic and therapeutic value of combining echocardiography and CT in native PVE. Multimodality imaging allowed timely identification of the underlying congenital substrate, precise characterization of vegetation burden, recognition of septic pulmonary emboli, and informed surgical decision-making in accordance with current guideline-based indications for right-sided IE surgery.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"10 9","pages":"ytag687"},"PeriodicalIF":0.7,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149059430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful management of subacute stent mal-apposition confirmed using optical coherence tomography following cardiac arrest due to spontaneous coronary artery dissection in a middle-aged woman: a case report.","authors":"Takeshi Mori, Hidekazu Aoyama, Miyuki Ando, Akimitsu Tanaka, Kazuo Kato","doi":"10.1093/ehjcr/ytag695","DOIUrl":"10.1093/ehjcr/ytag695","url":null,"abstract":"<p><strong>Background: </strong>In patients with spontaneous coronary artery dissection (SCAD), percutaneous coronary intervention is considered only in a limited number of situations. There are a few reports on therapeutic interventions for SCAD in the acute phase, none on those performed during the subacute phase.</p><p><strong>Case summary: </strong>A previously healthy 51-year-old woman was transported to our hospital, where ST elevation was noted on an electrocardiogram in the emergency room. Subsequently, she experienced ventricular fibrillation and cardiac arrest. Extracorporeal membrane oxygenation was initiated; coronary angiography (CAG) revealed severe right coronary artery stenosis. Intramural haematoma on intravascular ultrasonography led to SCAD diagnosis. Despite continued electrical defibrillation after extracorporeal membrane oxygenation initiation, the ventricular fibrillation persisted. However, after relieving ischaemia in the right coronary artery territory via stent placement, the ventricular fibrillation ceased. She developed a cerebral haemorrhage; from days 8 to 36, dual antiplatelet therapy (DAPT) had to be completely discontinued. On hospital day 56, although CAG detected no significant stenosis, optical coherence tomography (OCT) revealed marked stent mal-apposition. Additional dilation was performed using a non-compliant balloon. On follow-up OCT on day 196, most of the struts were covered by the intima. She received DAPT for 1 year, then switched to single antiplatelet therapy and remained free of cardiovascular events for 3 years.</p><p><strong>Discussion: </strong>Although no recommended treatments for mal-apposition following stenting for SCAD currently exist, dilation in the subacute phase may lead to a favourable outcome. This approach warrants consideration as a future therapeutic option for SCAD.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"10 9","pages":"ytag695"},"PeriodicalIF":0.7,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149059443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of high-flow/high-gradient aortic stenosis due to arteriovenous fistula: how to disarm pitfalls in valvular function assessment.","authors":"Massimo Mapelli, Valentina Mantegazza, Daniele Poma, Manuela Muratori","doi":"10.1093/ehjcr/ytag697","DOIUrl":"https://doi.org/10.1093/ehjcr/ytag697","url":null,"abstract":"","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"10 10","pages":"ytag697"},"PeriodicalIF":0.7,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13637575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149106026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transient sinus arrest caused by coronary spasm of the sinus node artery after pulsed field ablation for superior vena cava isolation: a case report.","authors":"Rintaro Hojo, Koichiro Yamaoka, Tomoyuki Arai, Masao Takahashi, Seiji Fukamizu","doi":"10.1093/ehjcr/ytag703","DOIUrl":"https://doi.org/10.1093/ehjcr/ytag703","url":null,"abstract":"<p><strong>Background: </strong>Pulsed field ablation (PFA) has emerged as a novel non-thermal ablation modality with preferential myocardial selectivity. However, its effects on adjacent structures, including the sinus node and its arterial supply, remain incompletely understood.</p><p><strong>Case summary: </strong>A 72-year-old woman underwent repeat ablation for recurrent paroxysmal atrial fibrillation. Following pulmonary vein isolation, superior vena cava (SVC) isolation was performed using a PFA system. Sinus rhythm was initially preserved. However, sinus arrest developed several minutes after ablation. High right atrial backup pacing was initiated. Coronary angiography revealed severe spasm of the sinus node artery. Sinus node function gradually recovered after supportive management. Post-procedural voltage mapping confirmed successful SVC isolation.</p><p><strong>Discussion: </strong>This case highlights delayed sinus arrest following SVC isolation using PFA, with angiographic evidence suggesting sinus node artery spasm. While multiple mechanisms may contribute to sinus node dysfunction after PFA, coronary vasospasm should be considered, particularly in cases with delayed onset.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"10 9","pages":"ytag703"},"PeriodicalIF":0.7,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13624275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149106022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodality imaging diagnosis of milk-of-calcium pericardial disease presenting as refractory ascites and mimicking liver cirrhosis.","authors":"Saroj Kumar Sahoo, Sindhu Rao Malla, Ramachandra Barik, Tara Prasad Tripathy","doi":"10.1093/ehjcr/ytag712","DOIUrl":"https://doi.org/10.1093/ehjcr/ytag712","url":null,"abstract":"","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"10 10","pages":"ytag712"},"PeriodicalIF":0.7,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13637593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149106042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitochondrial DNA depletion syndrome 12B: role of photon-counting computed tomography in detection of cardiac involvement-a case report.","authors":"Zixian Chen, Yinjia Wang, Wei Tian, Zhuoli Zhang, Gang Wang","doi":"10.1093/ehjcr/ytag709","DOIUrl":"10.1093/ehjcr/ytag709","url":null,"abstract":"<p><strong>Background: </strong>Mitochondrial DNA depletion syndrome 12B (MDS12B) is an ultra-rare autosomal recessive disorder caused by SLC25A4 mutations, which encode the mitochondrial adenine nucleotide translocator. Hypertrophic cardiomyopathy (HCM) is the predominant manifestation, yet detailed cardiac tissue characterization remains limited.</p><p><strong>Case summary: </strong>A 28-year-old male presented with a 17-year history of exertional palpitations and progressive fatigue. Echocardiography revealed severe concentric left ventricular hypertrophy with moderately reduced ejection fraction (42%). Photon-counting computed tomography (PCCT)-a novel spectral imaging technique-provided high-resolution coronary anatomy while quantifying extracellular volume expansion, late myocardial enhancement, and microvascular obstruction (MVO). Cardiac magnetic resonance (CMR) confirmed these findings. Genetic analysis identified a previously unreported homozygous SLC25A4 frameshift mutation (c.167_170del).</p><p><strong>Conclusion: </strong>This case provided the first evidence that PCCT can non-invasively detect both myocardial fibrosis and MVO in MDS12B, offering a potential alternative to CMR when contraindicated or unavailable. The novel frameshift variant expands the genotypic spectrum of <i>SLC25A4</i>-related mitochondrial depletion syndromes.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"10 10","pages":"ytag709"},"PeriodicalIF":0.7,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13662395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149180245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}