European Heart Journal: Case Reports最新文献

{"title":"A case report supporting early surgery in mitral valve infective endocarditis with recurrent cerebral infarcts.","authors":"Emeka B Kesieme, Benjamin Omoregbee, Dumbor L Ngaage","doi":"10.1093/ehjcr/ytae641","DOIUrl":"https://doi.org/10.1093/ehjcr/ytae641","url":null,"abstract":"<p><strong>Background: </strong>In patients with infective endocarditis, brain embolism portends a poor prognosis. The timing of surgery in patients who require emergency valve surgery in the setting of deteriorating level of consciousness from recurrent embolic events, and brain infarction with haemorrhagic transformation, remains controversial.</p><p><strong>Case summary: </strong>We report a case of a 54-year-old male who presented with <i>Streptococcus salivarius</i> mitral valve endocarditis, recurrent episodes of cerebral embolic infarctions with haemorrhagic transformation and deteriorating level of consciousness, and successfully underwent emergency mitral valve surgery without extension of the preoperative cerebral embolic complication or worsening of neurological symptoms.</p><p><strong>Discussion: </strong>Mitral valve surgery can be performed successfully in patients with mitral valve endocarditis and cerebral embolism earlier than the recommended 2-4 weeks, and this should be considered in deteriorating patients.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"8 12","pages":"ytae641"},"PeriodicalIF":0.8,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11650381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual transcatheter edge-to-edge repair in a patient with cardiac amyloidosis and severe secondary mitral and tricuspid regurgitation: a case report.","authors":"Julia Vogel, Peter Luedike, Amir Abbas Mahabadi, Tienush Rassaf, Lars Michel","doi":"10.1093/ehjcr/ytae601","DOIUrl":"10.1093/ehjcr/ytae601","url":null,"abstract":"<p><strong>Background: </strong>Mitral and tricuspid regurgitation in patients with cardiac amyloidosis (CA) pose significant diagnostic and therapeutic challenges due to its non-specific symptoms and limited treatment options. Transcatheter edge-to-edge repair (TEER) is complicated by altered cardiac geometry, advanced restriction, and potential amyloid valve deposits.</p><p><strong>Case summary: </strong>We present the case of dual TEER in a 79-year-old male with advanced transthyretin cardiac amyloidosis (ATTR-CA) and severe symptomatic mitral and tricuspid regurgitation. In a staged approach, TEER for both the mitral and tricuspid valves was successfully conducted, resulting in improved valvular function and symptom relief. Transvalvular gradients were 5 mmHg for mitral valve and 2 mmHg for tricuspid valve, each with mild residual regurgitation, improved clinical status, and regressive natriuretic peptides.</p><p><strong>Discussion: </strong>This case underscores the feasibility of dual TEER in CA patients with valvular involvement. Further research is necessary to optimize treatment strategies and address the multifaceted nature of this complex disease.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"8 12","pages":"ytae601"},"PeriodicalIF":0.8,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11635633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periannular extension of infective endocarditis with atrioventricular block successfully treated with antibiotic therapy after transcatheter aortic valve implantation: a case report.","authors":"Yuki Hirata, Shinichi Toriumi, Kenji Harada, Satoshi Hoshide, Kazuomi Kario","doi":"10.1093/ehjcr/ytae633","DOIUrl":"10.1093/ehjcr/ytae633","url":null,"abstract":"<p><strong>Background: </strong>Although transcatheter aortic valve implantation (TAVI) is performed for very elderly patients in whom surgical aortic valve replacement (SAVR) poses unacceptably high operative risk, some of these patients are ultimately forced to undergo open surgery when TAVI is complicated by infective endocarditis (IE). To our knowledge, there have been no reports of cases with periannular extension of IE and atrioventricular block successfully treated by antibiotics without valve replacement.</p><p><strong>Case summary: </strong>An 80-year-old Japanese man who had undergone TAVI developed IE with loss of consciousness on Day 39 after the procedure. Methicillin-resistant <i>Staphylococcus aureus</i> was detected in his blood culture. Electrocardiography (ECG) showed complete atrioventricular block. Transoesophageal echocardiography (TEE) detected vegetation on the anterior mitral leaflet, aorta, and common annulus. Transcatheter aortic valve implantation had been performed rather than SAVR to avoid the associated operative risks. Because his haemodynamic condition was stable, we decided upon antibiotic treatment alone. On Day 42 after admission, TEE showed a reduction in the size of the vegetation, and his ECG recovered to sinus rhythm.</p><p><strong>Discussion: </strong>Medical treatment alone was effective for a periannular extension of IE complicated with complete atrioventricular block in a very elderly patient after TAVI had been performed to avoid high operative risk.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"8 12","pages":"ytae633"},"PeriodicalIF":0.8,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11646121/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of familial catecholaminergic polymorphic ventricular tachycardia with a novel mutation in the ryanodine receptor 2.","authors":"Yoshikuni Shoji, Satoshi Hayashida, Hikaru Masuda, Eizo Tachibana, Yasuo Okumura","doi":"10.1093/ehjcr/ytae652","DOIUrl":"https://doi.org/10.1093/ehjcr/ytae652","url":null,"abstract":"<p><strong>Background: </strong>Catecholaminergic polymorphic ventricular tachycardia (CPVT) is suspected by clinical characteristics involving fatal arrhythmic events in childhood and adolescence. On the other hand, genetic testing is also important because the mutation site in the specific genes of CPVT is related to the risk of ventricular arrhythmias and gene penetrance.</p><p><strong>Case summary: </strong>We present a case of a 15-year-old male with a familial history of CPVT and a history of syncope at the age of 5. He experienced a cardiac arrest prompting out-of-hospital cardiopulmonary resuscitation, and his circulatory dynamics recovered. Multiple premature ventricular contractions inducted by a treadmill exercise test disappeared after a dosage of verapamil, flecainide, and nadolol, and a subcutaneous implantable cardioverter defibrillator was implanted. The novel pathogenic mutation with an insertion of histidine near the C-terminus of the RYR2 protein was identified by genetic testing in this case and his mother.</p><p><strong>Discussion: </strong>The RYR2 mutation in this case has not been previously reported and may be an intractable phenotype of CPVT associated with a strong familial history and fatal cardiac events even under adequate medical therapy.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"8 12","pages":"ytae652"},"PeriodicalIF":0.8,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11647922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Balloon-assisted bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary artery obstruction with en face view for patients exhibiting severe calcified leaflet: a case report.","authors":"Yuta Kobayashi, Yusuke Enta, Masaki Nakashima, Norio Tada","doi":"10.1093/ehjcr/ytae643","DOIUrl":"https://doi.org/10.1093/ehjcr/ytae643","url":null,"abstract":"<p><strong>Background: </strong>Balloon-assisted bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary artery obstruction (BA-BASILICA) enables valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) in patients at risk of coronary artery obstruction. However, its efficacy in patients with severely calcified leaflets remains unclear.</p><p><strong>Case summary: </strong>We report a 78-year-old woman with a deteriorated 21 mm Carpentier-Edwards PERIMOUNT Magna valve. Computed tomography showed severe calcification in the left coronary leaflet, extending above the left coronary artery (LCA) ostium, with a virtual transcatheter heart valve to coronary ostium distance of 3.7 mm, indicating a high risk of coronary obstruction after ViV-TAVI. We performed ViV-TAVI using the BA-BASILICA because of the patient's high surgical risks. Traversal of the calcified leaflet was successfully achieved using both en face and side views to visualize the traversal system's position in an area without calcification and in front of the LCA. After traversal, the leaflet was dilated with a balloon and accidentally split into two. A 20 mm SAPIEN 3 Ultra RESILIA valve was deployed. Despite initial procedural success, severe LCA stenosis developed due to leaflet compression. This was resolved by orthotopic stenting using an en face view to identify cells not covered by the bioprosthetic leaflet generated by BA-BASILICA.</p><p><strong>Discussion: </strong>To our knowledge, this is the first report of ViV-TAVI using the BA-BASILICA with an en face view of severely calcified leaflets. This case suggests that BA-BASILICA with an en face view could be effective for patients at high risk of coronary obstruction with severely calcified leaflets.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"8 12","pages":"ytae643"},"PeriodicalIF":0.8,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11647591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A shot through the heart: a case report on retained bullet causing cardiac tamponade.","authors":"Rakesh Shah, Thomas Dacey, Joseph Sebastian, Kenton Zehr, Shaun Cardozo","doi":"10.1093/ehjcr/ytae651","DOIUrl":"https://doi.org/10.1093/ehjcr/ytae651","url":null,"abstract":"<p><strong>Background: </strong>As a rare complication of penetrating chest trauma, one can occasionally find foreign bodies inside the pericardium. Even rarer is finding an intact bullet inside the pericardial cavity following the gunshot injury.</p><p><strong>Case summary: </strong>A 17-year-old male presented to the emergency department as a Level 1 trauma for multiple gunshot wounds. Upon arrival, the patient was tachycardic but normotensive. Physical exam was notable for several penetrating wounds to the chest and right clavicle. The initial chest X-ray demonstrated a metallic foreign body consistent with a bullet overlying the cardiac silhouette. Approximately 24 h into the hospital course, ST-segment elevation was noted on telemetry. An electrocardiogram demonstrated sinus tachycardia with diffuse ST-segment elevation in all leads, consistent with acute pericarditis. Over the following several hours, the patient gradually developed tamponade physiology, prompting a more emergent median sternotomy.</p><p><strong>Discussion: </strong>Although penetrating cardiac injury carries a high mortality rate, management of these patients and complications that may arise during their hospital course are rarely explained. The diagnosis of projectile chest trauma starts with history and physical examination. The primary diagnostic modalities are the X-ray, computed tomography scan of the chest, electrocardiogram, and echocardiogram. Management of a patient with cardiac gunshot depends largely on haemodynamic status. As in our case, a patient with haemodynamic instability is managed with emergency exploration and removal of the foreign body.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"8 12","pages":"ytae651"},"PeriodicalIF":0.8,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11647594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of the Edwards Sapien 3 bioprosthesis in atrioventricular valve position: a case series.","authors":"Alejandra Garretano, Raul Abella, Joaquin Fernández Doblas, Antonio Pamiès Catalán, Paola Dolader Codina, Ferran Gran Ipiña, Laura Marfil Godoy, Pedro Betrián Blasco","doi":"10.1093/ehjcr/ytae642","DOIUrl":"https://doi.org/10.1093/ehjcr/ytae642","url":null,"abstract":"<p><strong>Background: </strong>The Edwards Sapien percutaneous valve (Edwards Lifesciences, Irvine, CA, USA) is a promising therapeutic option for congenital atrioventricular disease mostly because of the possibility to accommodate somatic growth with balloon dilatation.</p><p><strong>Case summary: </strong>This article reports the performance of the Edwards Sapien 3 valve in atrioventricular valve position in four paediatric patients.</p><p><strong>Discussion: </strong>Despite aggressive antiplatelet and anticoagulation strategies, most patients showed early bioprosthesis dysfunction, with increasing gradient not related with somatic growth. The decrease in leaflet motility in the absence of thrombosis or pannus could be associated with the low-velocity flow and low-pressure gradient that exists between the atria and ventricles in small children. It is well-known graft lifespan is usually shorter in small children, but we hypothesize the possibility of a second factor that valve design is intended to support higher flow-velocity patterns and can present an early failure in low-flow low-pressure situation. More studies are necessary to provide reliable evidence.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"8 12","pages":"ytae642"},"PeriodicalIF":0.8,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11647584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of a surgical bipolar ablation device within an electroanatomical mapping system during epicardial ventricular tachycardia ablation via video-assisted thoracoscopic surgery: a case report.","authors":"Mark T Mills, Kirstin Welsh, Jonathan Sahu, Steven Hunter, Graeme J Kirkwood","doi":"10.1093/ehjcr/ytae648","DOIUrl":"https://doi.org/10.1093/ehjcr/ytae648","url":null,"abstract":"<p><strong>Background: </strong>Epicardial ventricular tachycardia (VT) ablation is an established approach in patients with epicardial arrhythmogenic foci and is most commonly performed via percutaneous access. An alternative approach is via video-assisted thoracoscopic surgery (VATS), although reports of this technique are limited to the use of catheter-based technologies for radiofrequency ablation delivery.</p><p><strong>Case summary: </strong>A 55-year-old man with non-ischaemic cardiomyopathy presented with recurrent VT despite medical therapy. Twelve-lead ECG and cardiac MRI were suggestive of an epicardial left ventricular lateral wall breakout. Epicardial ablation was successfully performed via VATS using a linear surgical bipolar ablation device with electroanatomical mapping (EAM) integration. Following ablation, VT was non-inducible. Other than six short episodes of non-sustained during initial follow-up (up to 6 weeks), the patient remained free of ventricular arrhythmias at 18 months with minimal anti-arrhythmic therapy.</p><p><strong>Discussion: </strong>Epicardial VT ablation via VATS is feasible and allows for integration of a surgical ablation device within an EAM system. This may serve as an alternative approach in patients with a failed percutaneous ablation, or those with adverse features for a successful percutaneous procedure.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"8 12","pages":"ytae648"},"PeriodicalIF":0.8,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11647582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"End-stage heart failure and heart transplant in cardiac sarcoidosis: a case series.","authors":"Maria Francesca Scuppa, Antonella Accietto, Anna Corsini, Maddalena Graziosi, Elena Biagini, Chiara Baldovini, Mario Sabatino, Luciano Potena","doi":"10.1093/ehjcr/ytae635","DOIUrl":"https://doi.org/10.1093/ehjcr/ytae635","url":null,"abstract":"<p><strong>Background: </strong>Diagnosing cardiac sarcoidosis (CS) is challenging. Immunosuppressive therapies are less effective in end-stage disease, and often heart transplant (HT) is the only available option. We present a series of advanced CS cases, requiring HT, along with a review of the literature evidence in this field.</p><p><strong>Case summary: </strong>Case 1: a 49-year-old man initially suspected of having arrhythmogenic cardiomyopathy (ACM) presented with heart failure (HF) and recurrent ventricular arrhythmias. The rapid clinical deterioration raised suspicion of an inflammatory aetiology, which was confirmed through endomyocardial biopsy, diagnosing CS. Despite immunosuppressive therapy, HT was required. Case 2: a 36-year-old woman presented with high-grade atrioventricular block and dilated cardiomyopathy (DCM), initially diagnosed as idiopathic. Due to worsening HF, she required HT. The pathological examination of the explanted heart revealed CS. Chronic subclinical antibody-mediated rejection was observed after HT. Case 3: a 44-year-old man presented with syncope and imaging suggesting ACM. He was referred for HT due to high ventricular arrhythmic burden. Cardiac sarcoidosis diagnosis was suspected due to pulmonary involvement and then confirmed on post-explant pathological exam. Post-HT pulmonary and cutaneous sarcoidosis reactivation were observed. Case 4: a 43-year-old man was diagnosed with pulmonary sarcoidosis after lung biopsy. Progression towards DCM was observed despite immunosuppressive therapy. Post-HT was characterized by multiple episodes of graft rejection.</p><p><strong>Discussion: </strong>This case series provides insights into mid- and long-term outcomes after HT for CS, highlighting the need for careful management of immunosuppression in these patients, balancing the adverse effects of chronic immunosuppression with the prevention of rejection and sarcoidosis recurrence.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"8 12","pages":"ytae635"},"PeriodicalIF":0.8,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11647515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brugada phenocopy in fulminant eosinophilic myocarditis: a case series.","authors":"Dai Kawauchi, Kei Yunoki, Tomohiro Yoshino, Takefumi Oka","doi":"10.1093/ehjcr/ytae646","DOIUrl":"https://doi.org/10.1093/ehjcr/ytae646","url":null,"abstract":"<p><strong>Background: </strong>Brugada phenocopy (BrP) is a condition that induces reversible Brugada-like electrocardiographic (ECG) changes in patients without true Brugada syndrome. We present two cases of fulminant eosinophilic myocarditis that showed Type 1 Brugada ECG changes in the early phase of the clinical course.</p><p><strong>Case summary: </strong>Case 1 was a 76-year-old man who developed fulminant eosinophilic myocarditis with ventricular tachycardia while hospitalized for heart failure. Case 2 was a 60-year-old man who presented with cardiogenic shock and was diagnosed with fulminant eosinophilic myocarditis. Both patients showed a Type 1 Brugada ECG at onset, and their ventricular function was greatly reduced. Regarding mechanical circulatory support, Case 1 was treated with venous-arterial extracorporeal membrane oxygenation and intra-aortic balloon pumping. Case 2 had venous-arterial extracorporeal membrane oxygenation and Impella CP insertion. Steroid therapy was introduced in both cases. In Case 1, the Type 1 Brugada ECG took 7 days to improve. Left ventricular function improved with time but right heart function was poor and right heart enlargement remained. In Case 2, the Type 1 Brugada ECG improved on the second day, and left and right heart function improved over time.</p><p><strong>Discussion: </strong>We report two cases of fulminant eosinophilic myocarditis with Brugada-like ECG and severe right heart dysfunction. BrP in acute myocarditis may be an indicator of right heart failure and an important ECG marker in determining the indication for mechanical circulatory support and improvement of right heart function.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"8 12","pages":"ytae646"},"PeriodicalIF":0.8,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11647588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}