European Heart Journal: Case Reports最新文献_第2页

The thrilling journey of a broken needle.

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European Heart Journal: Case Reports Pub Date : 2025-03-24 eCollection Date: 2025-04-01 DOI: 10.1093/ehjcr/ytaf141

Decai Zeng, Xiangling Cao, Ji Wu

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Surgical bailout for underexpanded transcatheter mitral valve replacement: addressing hemodynamic challenges.

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European Heart Journal: Case Reports Pub Date : 2025-03-24 eCollection Date: 2025-04-01 DOI: 10.1093/ehjcr/ytaf143

Chadi Aludaat, Arnaud Gay, Quentin Landolff

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Is altitude friend or foe in unrepaired congenital heart disease? A case report.

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European Heart Journal: Case Reports Pub Date : 2025-03-24 eCollection Date: 2025-03-01 DOI: 10.1093/ehjcr/ytaf115

Rebecca Fisher, Kali Hopkins, Krittika Pant, Arjun Kapoor, Ali N Zaidi

{"title":"Is altitude friend or foe in unrepaired congenital heart disease? A case report.","authors":"Rebecca Fisher, Kali Hopkins, Krittika Pant, Arjun Kapoor, Ali N Zaidi","doi":"10.1093/ehjcr/ytaf115","DOIUrl":"10.1093/ehjcr/ytaf115","url":null,"abstract":"Background: Some unrestrictive congenital shunts put patients at high risk for developing irreversible pulmonary vascular disease if not closed in the first year of life. Living at high altitude also places patients at risk for developing pulmonary hypertension. There are anecdotal data that living at high altitude may be protective against the development of shunt-related pulmonary vascular disease.Case summary: A 20-year-old female from Ecuador was found to have a large patent ductus arteriosus (PDA) and pulmonary hypertension after a murmur was auscultated. She had been living at altitude until 6 months prior. She was found to have a large PDA, systemic pulmonary artery (PA) pressure, and an elevated pulmonary vascular resistance index (PVRi) (33 wu ∗ m2) with minimal shunting (Qp:Qs 1:1). Vasodilatory testing with inhaled nitric oxide (iNO) and 100% FiO2 showed continued systemic PA pressure but a dramatic decrease in PVRi (12.5 wu ∗ m2) with an increase in left-to-right shunt (Qp:Qs 2:1). Living at high altitude causes hypoxic vasoconstriction. This vasoconstriction, which is typically reversible on descent to sea level, may decrease the left-to-right shunt and the irreversible downstream vascular changes that would normally occur in the setting of an unrestrictive PDA. Given the significant acute drop of this patient's vascular resistance with pulmonary vasodilator testing, she was started on oral pulmonary vasodilators. However, months later, the patient became increasingly symptomatic and repeat catheterization showed worsening cardiac function. Pulmonary vasodilators were stopped and the decision was made not to close the PDA.Discussion: Living at high altitude may be protective against the development of congenital shunt-related irreversible pulmonary vascular disease. However, in this case, it may not have been enough due to the complexity of anatomy.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 3","pages":"ytaf115"},"PeriodicalIF":0.8,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-interleukin-5 efficacy in an inclisiran-triggered eosinophilic myocarditis: a case report.

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European Heart Journal: Case Reports Pub Date : 2025-03-21 eCollection Date: 2025-04-01 DOI: 10.1093/ehjcr/ytaf127

Francesco Tartaglia, Maria Rita Messina, Stefania Rizzo, Enrico Heffler, Cristina Panico

{"title":"Anti-interleukin-5 efficacy in an inclisiran-triggered eosinophilic myocarditis: a case report.","authors":"Francesco Tartaglia, Maria Rita Messina, Stefania Rizzo, Enrico Heffler, Cristina Panico","doi":"10.1093/ehjcr/ytaf127","DOIUrl":"10.1093/ehjcr/ytaf127","url":null,"abstract":"Background: Eosinophilic myocarditis is a rare condition that can be associated with hypersensitivity reactions. Endomyocardial biopsy (EMB) is required for diagnosis, especially when cardiac magnetic resonance (CMR) is inconclusive. Immunosuppressive treatment is usually limited to corticosteroids.Case summary: Two days following an inclisiran injection for dyslipidaemia management, a 72-year-old Caucasian male with a history of coronary artery disease experienced progressive shortness of breath. Suspecting a hypersensitivity reaction to inclisiran, corticosteroids were administered. After discontinuing corticosteroids, the patient experienced recurrent dyspnoea. Laboratory tests indicated eosinophilia, increased serum immunoglobulin E (IgE), and positive specific serum IgE for Aspergillus fumigatus. Imaging tests and a lung biopsy revealed pulmonary aspergillosis, while CMR showed myocardial inflammation. The patient was initially treated with itraconazole and steroid therapy. However, he was re-hospitalized for worsening of the cardiac and respiratory condition after tapering steroids. A diagnosis of severe eosinophilic asthma associated with allergic bronchopulmonary aspergillosis was established. Löffler's endocarditis related to Aspergillus-induced eosinophilia was suspected and confirmed by repeated CMR and an EMB. Mepolizumab, an interleukin-5 (IL-5) inhibitor, was initiated resulting in symptom resolution and absence of inflammation at the 6-month follow-up CMR.Discussion: This case describes an uncommon response to inclisiran that resulted in Aspergillus-induced, steroid-dependent, eosinophilic systemic inflammation, resulting in severe asthma and endocarditis. It demonstrates how biological IL-5 inhibitors are effective in treating both components, emphasizing the necessity of a multidisciplinary strategy.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf127"},"PeriodicalIF":0.8,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11973448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful management of iliac artery perforation during peripheral angioplasty: a case report.

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European Heart Journal: Case Reports Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI: 10.1093/ehjcr/ytaf126

Saroj Kumar Sahoo, Debasis Panda, Debasis Acharya, Ramachandra Barik, Subhas Pramanik

{"title":"Successful management of iliac artery perforation during peripheral angioplasty: a case report.","authors":"Saroj Kumar Sahoo, Debasis Panda, Debasis Acharya, Ramachandra Barik, Subhas Pramanik","doi":"10.1093/ehjcr/ytaf126","DOIUrl":"10.1093/ehjcr/ytaf126","url":null,"abstract":"Background: Peripheral artery disease is commonly managed with percutaneous balloon angioplasty, now the standard for replacing open surgical methods. Although generally effective, this procedure can lead to complications, including the rare but potentially fatal vessel perforation. Prompt identification and intervention are crucial to avoid severe outcomes. This case report presents a rare instance of iliac artery perforation during angioplasty, successfully managed with a covered stent.Case summary: A 58-year-old male with poorly controlled type 2 diabetes mellitus presented with a non-healing ulcer and claudication in the left lower limb. Computed tomography (CT) angiography revealed complete occlusion of the left external iliac artery and significant stenosis of the right external iliac artery. During peripheral angioplasty, vessel perforation occurred after post-stenting balloon dilation, causing haemodynamic instability. Immediate management included balloon tamponade and deployment of a covered stent to seal the perforation. The patient's condition stabilized, and he was discharged with medications, including antiplatelets, anticoagulants, and statins. A follow-up CT angiography one month later showed a patent stent with good distal blood flow, and the patient remained clinically well.Discussion: Iliac artery perforation, though rare, is a severe complication of peripheral angioplasty demanding prompt and effective intervention to avert mortality and morbidity. This case demonstrates successful management using a covered stent, emphasizing the necessity of meticulous pre-procedural planning and intraoperative vigilance. The report also highlights the value of intravascular imaging and advanced techniques for vascular bed preparation in minimizing the risk of such complications during angioplasty.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 3","pages":"ytaf126"},"PeriodicalIF":0.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Balloon-expandable stent and self-expandable stent combined to treat coarctation of the aorta with descending aortic aneurysm: a case report.

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European Heart Journal: Case Reports Pub Date : 2025-03-18 eCollection Date: 2025-03-01 DOI: 10.1093/ehjcr/ytaf094

Xiaoxue Zhang, Shiliang Li, Xiantao Ma, Wajeehullahi Akilu, Cai Cheng

{"title":"Balloon-expandable stent and self-expandable stent combined to treat coarctation of the aorta with descending aortic aneurysm: a case report.","authors":"Xiaoxue Zhang, Shiliang Li, Xiantao Ma, Wajeehullahi Akilu, Cai Cheng","doi":"10.1093/ehjcr/ytaf094","DOIUrl":"10.1093/ehjcr/ytaf094","url":null,"abstract":"Background: Coarctation of the aorta is often associated with aortic dilatation, presenting a complex challenge for stent-based interventions. To address this, we have developed a novel combination of stent treatments to manage this dual pathology effectively.Case summary: A 29-year-old hypertensive patient with a coarctation of the aorta and a descending thoracic aortic aneurysm was evaluated for treatment. Contrast-enhanced computed tomography angiography (CTA) revealed significant narrowing at the aortic arch (Zone 2, proximal to the left subclavian artery) with a diameter of 5.04 mm. Additionally, the descending aorta had an aneurysmal dilation measuring 29.65 mm. We applied an innovative approach combining a balloon-expandable stent (BES) with a self-expandable stent (SES). Post-procedure CTA demonstrated favourable aortic remodelling, with the narrowest point of the aorta expanding from 5.04 to 15.95 mm.Discussion: This novel technique of implanting a BES within an SES effectively addresses both the aortic coarctation and the descending aortic aneurysm. By tripling the diameter of the coarctation, the approach maximizes aortic expansion while protecting the aorta. Moreover, the combination of these stents enhances overall stability, reducing the risk of stent migration or displacement.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 3","pages":"ytaf094"},"PeriodicalIF":0.8,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11914319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Possible solution for coronary cannulation through complete anti-anatomical deployment of self-expandable transcatheter heart valve using handmade spiral curve of catheter created by heat-gun.

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European Heart Journal: Case Reports Pub Date : 2025-03-18 eCollection Date: 2025-03-01 DOI: 10.1093/ehjcr/ytaf011

Masanori Yamamoto, Hirooki Higami, Yuki Kondo, Fubuki Kitahara

引用次数: 0

Primary pericardial synovial sarcoma: diagnosis of recurrence via multimodal imaging-a case report.

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European Heart Journal: Case Reports Pub Date : 2025-03-17 eCollection Date: 2025-04-01 DOI: 10.1093/ehjcr/ytaf132

Kanna Nakamura, Taiji Okada, Jiro Esaki, Shigeo Hara, Yutaka Furukawa

{"title":"Primary pericardial synovial sarcoma: diagnosis of recurrence via multimodal imaging-a case report.","authors":"Kanna Nakamura, Taiji Okada, Jiro Esaki, Shigeo Hara, Yutaka Furukawa","doi":"10.1093/ehjcr/ytaf132","DOIUrl":"10.1093/ehjcr/ytaf132","url":null,"abstract":"Background: Primary pericardial synovial sarcoma (PSS) is an extremely rare malignancy. Diagnosis and management primarily rely on multimodal imaging, with definitive diagnosis typically requiring a biopsy for histopathological confirmation. Although no established treatment protocol exists, complete tumour resection followed by adjuvant chemotherapy and radiotherapy is often considered.Case summary: A 68-year-old man presented with 1 month of shortness of breath and no significant medical history. Initial examination revealed cardiomegaly, a large pericardial effusion, and a solid mass adjacent to the right atrium. Multimodal imaging, including contrast-enhanced computed tomography and positron emission-T, identified a pericardial mass with metabolic activity. A thoracoscopic biopsy revealed atypical spindle-shaped cells, confirming the diagnosis of synovial sarcoma. This led to total tumour excision and lymph node dissection. Eighteen months post-surgery, imaging revealed recurrence, and the mass from the pericardium near the superior vena cava was resected via thoracotomy. Histopathological examination confirmed recurrent synovial sarcoma. Postoperative chemotherapy was administered; however, lung metastases developed, leading to further treatment 12 months post second surgery.Discussion: PSS is associated with poor prognosis and a high recurrence risk, highlighting the importance of regular follow-up imaging. While complete surgical resection remains the primary treatment, adjunct therapies may improve outcomes. This case underscores the need for multimodal imaging in diagnosing and monitoring PSS.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf132"},"PeriodicalIF":0.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11971480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ventricular fibrillation induced by atrial threshold search: a case report.

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European Heart Journal: Case Reports Pub Date : 2025-03-15 eCollection Date: 2025-03-01 DOI: 10.1093/ehjcr/ytaf131

David Sprenkeler, Ferry Hersbach, Ad Oomen, Clara van Ofwegen-Hanekamp, Mathias Meine

{"title":"Ventricular fibrillation induced by atrial threshold search: a case report.","authors":"David Sprenkeler, Ferry Hersbach, Ad Oomen, Clara van Ofwegen-Hanekamp, Mathias Meine","doi":"10.1093/ehjcr/ytaf131","DOIUrl":"10.1093/ehjcr/ytaf131","url":null,"abstract":"Background: Implantable cardioverter defibrillators (ICDs) have been proven to reduce the risk of sudden cardiac death from ventricular tachyarrhythmias. However, ICDs can sometimes induce malignant arrhythmias. We describe a case of ventricular fibrillation triggered by an automatic atrial threshold search.Case summary: A 72-year-old man presented after a syncopal episode. His medical history included moderate aortic regurgitation and a symptomatic second-degree atrioventricular (AV) block, for which he received a dual-chamber pacemaker in 2013, later upgraded to a CRT-D due to pacing-induced heart failure. ICD interrogation revealed an episode of ventricular fibrillation terminated by a shock. The arrhythmia started directly after an atrial threshold search. Extensive work-up did not reveal a cause of the arrhythmia, therefore, we considered it most likely that the atrial threshold test triggered the ventricular fibrillation. Atrial Capture Management was disabled, and the patient was discharged. No further ventricular arrhythmias or ICD therapies were observed.Discussion: Automatic threshold measurement algorithms are intended to ensure effective myocardial capture and enhance safety but can sometimes inadvertently cause arrhythmias. The underlying mechanism in this case may be related to the switch from biventricular to right ventricular (RV)-only pacing during Atrial Capture Management, which increases dispersion in repolarization, facilitating early afterdepolarizations and triggering polymorphic tachycardias. Notably, newer ICD models mitigate this risk by maintaining biventricular pacing during this test. This case underscores the need for careful programming and monitoring of ICD algorithms.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 3","pages":"ytaf131"},"PeriodicalIF":0.8,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11941468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Familial cardiac laminopathy with predominant atrial involvement: a case series of a family with LMNA mutation.

IF 0.8

European Heart Journal: Case Reports Pub Date : 2025-03-15 eCollection Date: 2025-04-01 DOI: 10.1093/ehjcr/ytaf129

Andreas Müssigbrodt, Romain Vergier, Maria Herrera Bethencourt, Astrid Monfort, Jocelyn Inamo, Veronique Fressart, Pascale Richard, Patrice Bouvagnet

{"title":"Familial cardiac laminopathy with predominant atrial involvement: a case series of a family with LMNA mutation.","authors":"Andreas Müssigbrodt, Romain Vergier, Maria Herrera Bethencourt, Astrid Monfort, Jocelyn Inamo, Veronique Fressart, Pascale Richard, Patrice Bouvagnet","doi":"10.1093/ehjcr/ytaf129","DOIUrl":"10.1093/ehjcr/ytaf129","url":null,"abstract":"Background: We present a case series detailing a family with familial cardiac laminopathy, including the female index patient, her father, her brother, and her daughter, all diagnosed with atrial arrhythmias, i.e. atrial fibrillation (AF), atrial flutter, and atrial premature contractions.Case summary: The index patient is known for frequent premature atrial contractions since the age of 35 years and for persistent AF since the age of 46 years. Rhythm control of symptomatic AF was achieved after two ablations. The brother of the index patient is known for asymptomatic persistent AF since the age of 26 years. He has opted for rate control and oral anticoagulation. Their father had persistent AF for many years before his death. The daughter of the index patient has asymptomatic frequent premature atrial contractions. She is under medical surveillance without specific medical treatment. All four patients have a normal ventricular systolic function. Genetic testing revealed a heterozygous missense variant in the LMNA gene causing a familial form of cardiac laminopathy, with clinical predisposition to atrial arrhythmias.Discussion: The familial occurrence of atrial arrhythmias without significant ventricular involvement in several family members with heterozygous LMNA missense mutation underscores the potential genetic component in cardiac arrhythmias, especially if arrhythmias occur in younger individuals without common risk factors.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf129"},"PeriodicalIF":0.8,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11969145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0