European Heart Journal: Case Reports最新文献_第3页

Cardiac AL amyloidosis in a veteran endurance athlete with pre-existing apical hypertrophic cardiomyopathy: a case report. 心脏AL淀粉样变的经验丰富的耐力运动员先前存在的根尖肥厚性心肌病：一个病例报告。

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European Heart Journal: Case Reports Pub Date : 2025-09-06 eCollection Date: 2025-09-01 DOI: 10.1093/ehjcr/ytaf443

Emmanuel Androulakis, Szymon Musiol, Michael Papadakis, Maria Teresa Tome Esteban

{"title":"Cardiac AL amyloidosis in a veteran endurance athlete with pre-existing apical hypertrophic cardiomyopathy: a case report.","authors":"Emmanuel Androulakis, Szymon Musiol, Michael Papadakis, Maria Teresa Tome Esteban","doi":"10.1093/ehjcr/ytaf443","DOIUrl":"10.1093/ehjcr/ytaf443","url":null,"abstract":"Background: Patients with mild phenotypes of chronic cardiomyopathies are often followed up over time, and there is a temptation to assume a change in symptom status or investigation results is due to the original pathology. The possibility of acquired pathology must be considered in these patients.Case summary: We present a case of a middle-aged veteran endurance athlete followed up for a mild phenotype of apical hypertrophic cardiomyopathy originally picked up due to an asymptomatic abnormal electrocardiogram (ECG). He developed subtle symptoms and morphological changes in his investigations (ECG, echocardiography, exercise tolerance test (ETT), and magnetic resonance imaging (MRI)). Due to the previously quiescent phenotype, a diagnosis of coexistent amyloid light-chain (AL) cardiac amyloidosis secondary to IgA lambda multiple myeloma was made.Discussion: This case underscores the importance of paying attention to subtle changes in symptoms and morphology when managing patients with mild phenotypes and athletes, and considering alternative pathology when these occur. Multimodality imaging is essential in the investigation of such patients.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 9","pages":"ytaf443"},"PeriodicalIF":0.8,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12477468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erdheim-Chester disease presenting with aortic valvulopathy and coronary stenosis: a diagnostic challenge. 以主动脉瓣病变和冠状动脉狭窄为表现的Erdheim-Chester病：一个诊断挑战。

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European Heart Journal: Case Reports Pub Date : 2025-09-04 eCollection Date: 2025-09-01 DOI: 10.1093/ehjcr/ytaf431

Asaki Saijo, Chinatsu Komiyama, Takahide Kodama

引用次数: 0

Long-term hydroxychloroquine use resulting in cardiomyopathy and conduction abnormalities: a case report. 长期使用羟氯喹导致心肌病和传导异常1例报告。

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European Heart Journal: Case Reports Pub Date : 2025-09-03 eCollection Date: 2025-09-01 DOI: 10.1093/ehjcr/ytaf377

Timothy Ryan, Laura Luttrell, Amit Shah, Kaitlyn Lam, Peter Dias, Aws Jasim, Andrew Laycock, Vimal Patel

{"title":"Long-term hydroxychloroquine use resulting in cardiomyopathy and conduction abnormalities: a case report.","authors":"Timothy Ryan, Laura Luttrell, Amit Shah, Kaitlyn Lam, Peter Dias, Aws Jasim, Andrew Laycock, Vimal Patel","doi":"10.1093/ehjcr/ytaf377","DOIUrl":"10.1093/ehjcr/ytaf377","url":null,"abstract":"Background: Diagnosing the cause of undifferentiated left ventricular hypertrophy (LVH) in a patient with progressive heart failure symptoms can present a diagnostic challenge, with potential for both inherited and acquired aetiologies. Hydroxychloroquine-induced cardiomyopathy (HCQ-CM) is a rare complication of long-term hydroxychloroquine use. This case report highlights its clinical presentation, key differential diagnoses, and treatment strategies.Case summary: A 56-year-old female with a longstanding history of systemic lupus erythematosus presented with progressive dyspnoea, fatigue, and fluid overload. Initial investigation revealed LVH with restrictive physiology, elevated cardiac biomarkers, and non-specific findings on echocardiography suggestive of an infiltrative cardiomyopathy. The diagnosis remained uncertain until an endomyocardial biopsy (EMB) confirmed HCQ-CM, characterized by the presence of curvilinear inclusion bodies. Following cessation of HCQ, there was a significant clinical improvement, with the patient achieving NYHA class I status at 6 months follow-up.Conclusion: This case highlights the critical importance of considering HCQ-CM, in the differential diagnosis of unexplained heart failure and LVH in patients on long-term HCQ therapy. A multi-parametric diagnostic approach-including EMB and genetic testing where appropriate-is essential to identify potentially reversible causes of cardiomyopathy and enable timely therapeutic adjustments.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 9","pages":"ytaf377"},"PeriodicalIF":0.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imaging manifestations of a rare case: giant coronary artery aneurysm with thrombosis. 巨冠状动脉瘤合并血栓的影像学表现1例。

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European Heart Journal: Case Reports Pub Date : 2025-09-03 eCollection Date: 2025-09-01 DOI: 10.1093/ehjcr/ytaf439

Lianze Du, Yao Yu, Qinghe Han

引用次数: 0

Epinephrine and the paradox of Kounis syndrome: a case series and review of management. 肾上腺素与库尼斯综合征的悖论：一个病例系列和管理回顾。

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European Heart Journal: Case Reports Pub Date : 2025-09-03 eCollection Date: 2025-09-01 DOI: 10.1093/ehjcr/ytaf414

Mohammad Hamideh, Alec Rhodes, Aswin Srinivasan, Shudipan Chakraborty, Christopher Hawkins, Aakash Kumar, Hafez Golzarian

引用次数: 0

When chest pain is not what it seems: time for right diagnosis and right treatment-a case report. 当胸痛并不像看上去的那样：是时候做出正确的诊断和治疗了——一份病例报告。

IF 0.8

European Heart Journal: Case Reports Pub Date : 2025-09-03 eCollection Date: 2025-09-01 DOI: 10.1093/ehjcr/ytaf410

Giulia La Vecchia, Ludovica Leo, Antonio Maria Leone, Rocco A Montone

{"title":"When chest pain is not what it seems: time for right diagnosis and right treatment-a case report.","authors":"Giulia La Vecchia, Ludovica Leo, Antonio Maria Leone, Rocco A Montone","doi":"10.1093/ehjcr/ytaf410","DOIUrl":"10.1093/ehjcr/ytaf410","url":null,"abstract":"Background: Chest pain is a common reason for emergency department (ED) visits, yet not all cases are attributable to coronary artery disease (CAD). The 2024 European Society of Cardiology (ESC) guidelines emphasize the importance of invasive coronary function testing in patients with angina and non-obstructive coronary arteries. Understanding alternative causes of chest pain is crucial for appropriate diagnosis and management.Case summary: A 58-year-old woman with hypertension, prediabetes, and a history of Takotsubo Syndrome presented with recurrent chest pain episodes, prompting multiple ED visits. Initial cardiac evaluations, including electrocardiogram (ECG), troponin levels, and ECG stress testing, were unremarkable. Repeated invasive coronary angiography (ICA) with a full physiological assessment ruled out obstructive CAD, microvascular dysfunction, and coronary vasospasm, suggesting a 'sensitive heart syndrome'. Further evaluation revealed a spinal schwannoma at the thoracic level, compressing the anterior spinal roots. Neuropathic chest pain was confirmed, and treatment with pregabalin led to symptom relief.Discussion: This case highlights the importance of a structured stepwise diagnostic approach to chest pain. When cardiac causes are excluded, alternative diagnoses such as neuropathic pain should be considered.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 9","pages":"ytaf410"},"PeriodicalIF":0.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ECG challenge: inversion without infarction. 心电图挑战：无梗死倒置。

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European Heart Journal: Case Reports Pub Date : 2025-09-02 eCollection Date: 2025-09-01 DOI: 10.1093/ehjcr/ytaf438

Nithin George

引用次数: 0

A multifaceted clinical portrait of Ebstein's anomaly: a case series. Ebstein异常的多面临床描述：一个病例系列。

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European Heart Journal: Case Reports Pub Date : 2025-09-02 eCollection Date: 2025-09-01 DOI: 10.1093/ehjcr/ytaf424

Panayotis K Vlachakis, Eva Nyktari, George Oikonomou, Anastasios Apostolos, Skevos Sideris, Konstantinos Toutouzas, Costas Tsioufis, Maria Drakopoulou

{"title":"A multifaceted clinical portrait of Ebstein's anomaly: a case series.","authors":"Panayotis K Vlachakis, Eva Nyktari, George Oikonomou, Anastasios Apostolos, Skevos Sideris, Konstantinos Toutouzas, Costas Tsioufis, Maria Drakopoulou","doi":"10.1093/ehjcr/ytaf424","DOIUrl":"10.1093/ehjcr/ytaf424","url":null,"abstract":"Background: It was in 1866 when Wilhelm Ebstein first described a rare case of a 19-year-old cyanotic patient with tricuspid valve regurgitation caused by a congenital malformation. Since then, Ebstein's anomaly (EA) has been recognized as a condition that exhibits a diverse clinical course with a formidable challenge for clinicians in terms of diagnosis, management, and prognosis.Case summary: We present a case series of four patients with EA, shedding light on the varied clinical manifestations, treatment approaches, and outcomes that underscore the multifaceted nature of this condition.Discussion: The management of EA requires a comprehensive and individualized approach in specialized centres. The cardiologists responsible for the long-term care of these patients are faced with various challenging 'dilemmas' in the clinical course of the disease at different stages. The evolving landscape of cardiology offers a promising avenue for improving the outcomes and quality of life of patients with EA.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 9","pages":"ytaf424"},"PeriodicalIF":0.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12461249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145184903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rescue percutaneous transluminal septal myocardial ablation for difficult ventilator weaning in drug-resistant hypertrophic obstructive cardiomyopathy: a case report. 经皮腔内室间隔心肌消融治疗耐药肥厚性梗阻性心肌病呼吸机困难脱机1例。

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European Heart Journal: Case Reports Pub Date : 2025-09-02 eCollection Date: 2025-09-01 DOI: 10.1093/ehjcr/ytaf435

Keisuke Nakabayashi, Takeshi Hayashi, Shota Kaiga, Nobuhito Kaneko, Minoru Shimizu

{"title":"Rescue percutaneous transluminal septal myocardial ablation for difficult ventilator weaning in drug-resistant hypertrophic obstructive cardiomyopathy: a case report.","authors":"Keisuke Nakabayashi, Takeshi Hayashi, Shota Kaiga, Nobuhito Kaneko, Minoru Shimizu","doi":"10.1093/ehjcr/ytaf435","DOIUrl":"10.1093/ehjcr/ytaf435","url":null,"abstract":"Background: Hypertrophic obstructive cardiomyopathy is a genetic cardiac disorder characterized by left ventricular outflow tract (LVOT) obstruction that can lead to haemodynamic instability. Managing preload in mechanically ventilated patients with hypertrophic obstructive cardiomyopathy is challenging because volume depletion exacerbates LVOT obstruction, whereas fluid overload induces pulmonary congestion. Weaning from mechanical ventilation (MV) in such cases requires precise volume management; however, conventional pharmacological therapy may be insufficient. Moreover, the role of percutaneous transluminal septal myocardial ablation (PTSMA) in the acute phase of symptomatic hypertrophic obstructive cardiomyopathy remains unclear.Case summary: A 51-year-old woman was admitted with cerebral haemorrhage and underwent emergency craniotomy. The patient experienced repeated episodes of acute heart failure, leading to several resuscitation attempts and requiring extended MV. Echocardiography revealed severe LVOT obstruction (peak LVOT pressure gradient, 119.7 mmHg). Attempts at volume optimization and pharmacological therapy failed to wean from MV or achieve haemodynamic stability. Given the patient's critical condition, rescue PTSMA was performed, which significantly reduced the LVOT gradient, thereby allowing aggressive volume reduction with haemodialysis and successful extubation within a week.Discussion: This case highlights the role of PTSMA as a rescue therapy for patients with hypertrophic obstructive cardiomyopathy experiencing difficulty weaning from MV and haemodynamic instability. Further studies are warranted to evaluate the safety, efficacy, and long-term outcomes of PTSMA as an acute-phase intervention in critically ill patients with hypertrophic obstructive cardiomyopathy.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 9","pages":"ytaf435"},"PeriodicalIF":0.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mavacamten for treatment of symptomatic mid-ventricular obstruction in hypertrophic cardiomyopathy: a case report. 马伐卡坦治疗肥厚性心肌病症状性中心室梗阻1例。

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European Heart Journal: Case Reports Pub Date : 2025-09-02 eCollection Date: 2025-09-01 DOI: 10.1093/ehjcr/ytaf423

Samuel Hunziker, Philip Haaf, Annina S Vischer

引用次数: 0