Christian-H Heeger, Henning Rolfes, Martin W Bergmann, Maxim Didenko
{"title":"Novel multielectrode mapping catheter for targeting left ventricular summit derived premature ventricular contractions within the great cardiac vein: first-in-man.","authors":"Christian-H Heeger, Henning Rolfes, Martin W Bergmann, Maxim Didenko","doi":"10.1093/ehjcr/ytaf254","DOIUrl":"10.1093/ehjcr/ytaf254","url":null,"abstract":"","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 6","pages":"ytaf254"},"PeriodicalIF":0.8,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12128077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144208052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G Padilla-Rodríguez, A Gómez-González, M Barquero-Alemán, I Méndez-Santos, J C García-Rubira
{"title":"Acute myocardial infarction due to type A aortic dissection in a patient with corrected congenital cardiopathy: a case report.","authors":"G Padilla-Rodríguez, A Gómez-González, M Barquero-Alemán, I Méndez-Santos, J C García-Rubira","doi":"10.1093/ehjcr/ytaf250","DOIUrl":"10.1093/ehjcr/ytaf250","url":null,"abstract":"<p><strong>Background: </strong>Ascending aortic dissection rarely presents as acute myocardial infarction, and when it does, its diagnosis is even more challenging.</p><p><strong>Case summary: </strong>We present a case of a young male with corrected congenital heart disease and a giant ascending aorta aneurysm. He was admitted to hospital for chest pain and was diagnosed with acute anterior myocardial infarction. Imaging tests showed dissection of the ascending aorta. He required complex cardiovascular surgery for Dacron tube implantation to treat the giant ascending aortic aneurysm.</p><p><strong>Discussion: </strong>This case is a reminder of how important adequate differential diagnosis is in the context of myocardial infarction, as well as the management of acute aortic syndrome. In our patient, the patency of the left coronary artery was verified using imaging techniques, and the most likely cause of the infarction could be the aneurysm extrinsically compressing the coronary artery.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 6","pages":"ytaf250"},"PeriodicalIF":0.8,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Borja Guerrero Cervera, Raquel López-Vilella, Víctor Donoso Trenado, Julia Martínez Solé, Luis Martínez Dolz, Luis Almenar-Bonet
{"title":"Solid organ transplantation in heart transplant patients: description of two highly complex cases: a case series.","authors":"Borja Guerrero Cervera, Raquel López-Vilella, Víctor Donoso Trenado, Julia Martínez Solé, Luis Martínez Dolz, Luis Almenar-Bonet","doi":"10.1093/ehjcr/ytaf226","DOIUrl":"10.1093/ehjcr/ytaf226","url":null,"abstract":"<p><strong>Background: </strong>Heart transplantation has become a developed and routine technique, constituting the treatment of choice in advanced heart failure when other therapies have failed. The number of transplanted patients who require transplantation of another organ in their evolution or simultaneous transplantation is increasing. Experience in this scenario is still limited.</p><p><strong>Case summary: </strong>We present two unusual cases of patients who, after receiving a cardio-bipulmonary transplant and isolated cardiac transplant, respectively, require sequential transplantation of another organ in their evolution. In the first case, as a consequence of immunosuppressive drugs, there is a progressive deterioration of renal function that requires renal transplantation after years of peritoneal dialysis. In the second case, shortly after cardiac transplantation, severe emphysematous chronic obstructive pulmonary disease of quick evolution was diagnosed, requiring one-lung transplantation after needing ambulatory oxygen therapy. The evolutionary complications of both cases are presented.</p><p><strong>Discussion: </strong>Patients with multiple organ transplantation represent a challenge as this situation is less frequent, due to the added difficulties in the adjustment of immunosuppression and the specific complications of each organ. However, multidisciplinary follow-up of these patients has led to improved survival.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 5","pages":"ytaf226"},"PeriodicalIF":0.8,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alessio Petrone, Laura Perrotta, Giuseppe Ricciardi, Paolo Pieragnoli, Andrea Colella
{"title":"High-risk accessory pathway associated with a rare right atrial diverticulum: a case report.","authors":"Alessio Petrone, Laura Perrotta, Giuseppe Ricciardi, Paolo Pieragnoli, Andrea Colella","doi":"10.1093/ehjcr/ytaf236","DOIUrl":"10.1093/ehjcr/ytaf236","url":null,"abstract":"<p><strong>Background: </strong>Right atrial (RA) diverticulum is a rare malformation that can, in some cases, harbour an accessory pathway (AP). This report describes the case of a patient with RA diverticulum associated with a high-risk right posteroseptal AP. Successful radiofrequency catheter ablation was performed, eliminating the AP and resolving the patient's pre-excitation.</p><p><strong>Case summary: </strong>A 33-year-old man with a 15-years history of an AP presented with two isolated, self-limited episodes of palpitations. A 12-lead ECG during normal sinus rhythm showed pre-excitation consistent with a right posteroseptal AP. The electrophysiological study identified an inducible antidromic atrioventricular tachycardia (tachycardia cycle length = 220 ms) due to a high-risk AP with robust conduction in both antegrade and retrograde directions. The AP was localized inside a RA diverticulum near the tricuspid annulus, confirmed through angiography and 3D high-density mapping. Radiofrequency ablation was successfully performed at the top of the diverticulum at a site recording an AP potential. To further characterize the diverticulum, a cardiac magnetic resonance was performed, and showed a maximum dimension of 20 × 16 mm. Since the diverticulum did not cause any haemodynamic impact, surgical intervention was deemed unnecessary.</p><p><strong>Discussion: </strong>'Anatomical' APs are rare, often described in the literature as diverticula of the coronary sinus. However, RA diverticula associated with APs are exceedingly uncommon, with only a few cases reported. This case underscores the importance of considering structural abnormalities like RA diverticula in patients presenting with unusual arrhythmic patterns and highlights the effectiveness of radiofrequency ablation as a definitive treatment in such complex scenarios.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 5","pages":"ytaf236"},"PeriodicalIF":0.8,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12100617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fulminant lymphocytic myocarditis with unusual giant cell detection: a case report.","authors":"Takuma Sato, Yoshihiko Ikeda, Osamu Seguchi, Satsuki Fukushima, Yasumasa Tsukamoto","doi":"10.1093/ehjcr/ytaf248","DOIUrl":"10.1093/ehjcr/ytaf248","url":null,"abstract":"<p><strong>Background: </strong>An accurate and rapid pathologic diagnostic in fulminant myocarditis is crucial for appropriate therapeutic decision-making. Since giant cells can appear in various conditions, careful judgment based on repeated imaging, pathological analysis, and close clinical follow-up is essential to make precise decisions.</p><p><strong>Case summary: </strong>A previously healthy 36-year-old woman was admitted to the hospital with haemodynamic compromise requiring mechanical circulatory support. Pathologic findings of left ventricular (LV) at the time of left ventricular assist device (LVAD) implantation confirmed the diagnosis of lymphocytic myocarditis. Cardiac function had gradually recovered, and LVAD was successfully weaned on post-operative day (POD) 10. However, surgical biopsy of LV at the time of LVAD removal revealed multinucleated giant cell formation, resulting in administered prednisolone for 2 weeks. After the withdrawal of prednisolone, pathologic findings of the right ventricle (RV) endomyocardial biopsy (EMB) specimens obtained on POD 21 showed continuous resolving myocarditis without any giant cell formation. Several additional examinations showed no evidence of an autoimmune-related disease background. The cardiac catheterisation performed on POD 85 showed normal hemodynamics with preserved LV function and EMB of the RV showed resolving myocarditis without giant cells. One year later, the patient was well without immunosuppressive therapy.</p><p><strong>Discussion: </strong>The multinucleated giant cell formation might be the accidental result of the fusion of macrophages that had ingested myocardial calcifications or degenerative macromolecules formed by the severe inflammatory process of lymphocytic myocarditis. The massive calcium deposition in both ventricles on CT and the positivity of monocytic markers in giant cells support this hypothesis.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 6","pages":"ytaf248"},"PeriodicalIF":0.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12130792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Excessive left ventricular trabeculations mimicking a thrombus.","authors":"Gurnoor Singh, Matthew Shotwell, Dinesh Kalra","doi":"10.1093/ehjcr/ytaf228","DOIUrl":"10.1093/ehjcr/ytaf228","url":null,"abstract":"","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 5","pages":"ytaf228"},"PeriodicalIF":0.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12099032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perioperative management of transcatheter aortic valve implantation in acquired von Willebrand syndrome secondary to monoclonal gammopathy: a case report.","authors":"Gaia Filiberti, Alessandro Giaj Levra, Mauro Chiarito, Bernhard Reimers, Gianluigi Condorelli","doi":"10.1093/ehjcr/ytaf205","DOIUrl":"10.1093/ehjcr/ytaf205","url":null,"abstract":"<p><strong>Background: </strong>Acquired von Willebrand syndrome (AvWS) is a rare bleeding disorder associated with conditions like monoclonal gammopathy of undetermined significance (MGUS). It results from monoclonal antibodies binding to von Willebrand factor (vWF), leading to rapid clearance of vWF and factor VIII (FVIII). Of note, any condition increasing shear stress, such as aortic stenosis (AS), can exacerbate AvWS.</p><p><strong>Case summary: </strong>We report the case of an 81-year-old man with AvWS secondary to MGUS who underwent transcatheter aortic valve implantation (TAVI) for severe aortic stenosis. Pre-operative intravenous immunoglobulins (IVIG) were administered, which normalized FVIII and vWF levels. TAVI was performed without specific haemostatic measures other than vascular closure devices. There were no bleeding complications, and the patient was discharged without antiplatelet therapy. At one-year follow-up, he had no thrombotic or haemorrhagic events.</p><p><strong>Discussion: </strong>We report the management of a patient affected by AvWS secondary to MGUS who underwent TAVI for severe AS. IVIG were administered preoperatively to temporarily normalize coagulation, as their mechanism of action directly inhibits the increased consumption of vWF. Due to the increased bleeding risk associated with AvWS, antiplatelet therapy was not initiated upon discharge.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 5","pages":"ytaf205"},"PeriodicalIF":0.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ghassan Moubarak, Alexandre Zhao, Marc Semichon, Caroline Grimard, Ardalan Sharifzadehgan
{"title":"Catheter ablation of a mechanically traumatized atrioventricular accessory pathway by targeting its ventricular insertion determined by pace mapping: a case report.","authors":"Ghassan Moubarak, Alexandre Zhao, Marc Semichon, Caroline Grimard, Ardalan Sharifzadehgan","doi":"10.1093/ehjcr/ytaf253","DOIUrl":"10.1093/ehjcr/ytaf253","url":null,"abstract":"<p><strong>Background: </strong>Catheter ablation is a highly effective treatment of atrioventricular accessory pathways (APs). Catheter-induced mechanical trauma of the AP is not infrequent during electrophysiology study and can lead to procedure discontinuation. We present an alternative method to successfully ablate a persistently traumatized AP.</p><p><strong>Case summary: </strong>A 15-year-old patient was referred for ablation of a symptomatic parahisian AP. Unfortunately, the AP was mechanically traumatized during catheter placement, and conduction did not resume after a 45-min waiting period. We proceeded to determine the ventricular insertion of the AP. Pace mapping was performed at the ventricular aspect of the tricuspid annulus with bipolar pacing from the ablation catheter. Using electroanatomic mapping, a correlation map between the maximally pre-excited QRS morphology (recorded at the beginning of the electrophysiological study) and the pace-mapped QRS was displayed. The highest correlation was 94%. The area delimited by the 3 best pace-map matching points was considered the target area, and radiofrequency applications were delivered. No recurrence of pre-excitation or palpitations were observed during 6 months of follow-up.</p><p><strong>Discussion: </strong>Determining the distal ventricular insertion of a mechanically traumatized AP is feasible, by comparing a maximally pre-excited QRS with the paced-mapped QRS. Electroanatomic correlation mapping may help delineate a limited target area before ablation.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 5","pages":"ytaf253"},"PeriodicalIF":0.8,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}