Epidemiology and Infection最新文献_第5页

Lyme borreliosis awareness and risk perception: a survey in 20 European countries. 莱姆病的认识和风险认知——一项对20个欧洲国家的调查。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-01-23 DOI: 10.1017/S0950268825000068

L Hannah Gould, Emily Colby, Andreas Pilz, Gordon Brestrich, Kate Halsby, Patrick H Kelly, Jennifer C Moisi, James H Stark

引用次数: 0

An outbreak of Shiga toxin-producing Escherichia coli serotype O103:H2 associated with unpasteurized soft cheese, England and Wales, 2022. 产志贺毒素的大肠杆菌血清型O103:H2与未经巴氏消毒的软奶酪有关，英格兰和威尔士，2022年。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-01-22 DOI: 10.1017/S0950268824001523

Ellen Heinsbroek, Eleanor Blakey, Alex Simpson, Neville Q Verlander, David R Greig, Frieda Jorgensen, Andrew Nelson, Amy Douglas, Sooria Balasegaram, Claire Jenkins, Richard Elson

{"title":"An outbreak of Shiga toxin-producing Escherichia coli serotype O103:H2 associated with unpasteurized soft cheese, England and Wales, 2022.","authors":"Ellen Heinsbroek, Eleanor Blakey, Alex Simpson, Neville Q Verlander, David R Greig, Frieda Jorgensen, Andrew Nelson, Amy Douglas, Sooria Balasegaram, Claire Jenkins, Richard Elson","doi":"10.1017/S0950268824001523","DOIUrl":"10.1017/S0950268824001523","url":null,"abstract":"In July 2022, a genetically linked and geographically dispersed cluster of 12 cases of Shiga toxin-producing Escherichia coli (STEC) O103:H2 was detected by the UK Health Security Agency using whole genome sequencing. Review of food history questionnaires identified cheese (particularly an unpasteurized brie-style cheese) and mixed salad leaves as potential vehicles. A case-control study was conducted to investigate exposure to these products. Case food history information was collected by telephone. Controls were recruited using a market research panel and self-completed an online questionnaire. Univariable and multivariable analyses were undertaken using Firth Logistic Regression. Eleven cases and 24 controls were included in the analysis. Consumption of the brie-style cheese of interest was associated with illness (OR 57.5, 95% confidence interval: 3.10-1,060). Concurrently, the production of the brie-style cheese was investigated. Microbiological sample results for the cheese products and implicated dairy herd did not identify the outbreak strain, but did identify the presence of stx genes and STEC, respectively. Together, epidemiological, microbiological, and environmental investigations provided evidence that the brie-style cheese was the vehicle for this outbreak. Production of unpasteurized dairy products was suspended by the business operator, and a review of practices was performed.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":"152 ","pages":"e172"},"PeriodicalIF":2.5,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular detection and typing of pathogenic Leptospira species from livestock and small mammals in Uganda. 乌干达家畜和小型哺乳动物致病性钩端螺旋体的分子检测和分型。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-01-22 DOI: 10.1017/S0950268825000044

Lordrick Alinaitwe, Martin Wainaina, Salome Dürr, Clovice Kankya, Velma Kivali, James Bugeza, Christopher Joshua Aturinda, Ashiraf Lubega, Anne Mayer-Scholl, Jolly Justine Hoona, Peter Bahn, Jens Andre Hammerl, Kristina Roesel, Elizabeth Anne Jessie Cook, Martin H Richter

{"title":"Molecular detection and typing of pathogenic Leptospira species from livestock and small mammals in Uganda.","authors":"Lordrick Alinaitwe, Martin Wainaina, Salome Dürr, Clovice Kankya, Velma Kivali, James Bugeza, Christopher Joshua Aturinda, Ashiraf Lubega, Anne Mayer-Scholl, Jolly Justine Hoona, Peter Bahn, Jens Andre Hammerl, Kristina Roesel, Elizabeth Anne Jessie Cook, Martin H Richter","doi":"10.1017/S0950268825000044","DOIUrl":"10.1017/S0950268825000044","url":null,"abstract":"Leptospira are bacteria that cause leptospirosis in both humans and animals. Human Leptospira infections in Uganda are suspected to arise from animal-human interactions. From a nationwide survey to determine Leptospira prevalence and circulating sequence types in Uganda, we tested 2030 livestock kidney samples, and 117 small mammals (rodents and shrews) using real-time PCR targeting the lipL32 gene. Pathogenic Leptospira species were detected in 45 livestock samples but not in the small mammals. The prevalence was 6.12% in sheep, 4.25% in cattle, 2.08% in goats, and 0.46% in pigs. Sequence typing revealed that Leptospira borgpetersenii, Leptospira kirschneri, and Leptospira interrogans are widespread across Uganda, with 13 novel sequence types identified. These findings enhance the East African MLST database and support the hypothesis that domesticated animals may be a source of human leptospirosis in Uganda, highlighting the need for increased awareness among those in close contact with livestock.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e50"},"PeriodicalIF":2.5,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiological and osteoarticular involvement sites' characteristics of multiple osteoarticular tuberculosis: a scoping review. 多发性骨关节结核的流行病学和骨关节受累部位特征：一个范围综述。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-01-21 DOI: 10.1017/S095026882400150X

Jian Zhou, Xuanjie Yang, Yong Hu, Shijun Li

{"title":"Epidemiological and osteoarticular involvement sites' characteristics of multiple osteoarticular tuberculosis: a scoping review.","authors":"Jian Zhou, Xuanjie Yang, Yong Hu, Shijun Li","doi":"10.1017/S095026882400150X","DOIUrl":"10.1017/S095026882400150X","url":null,"abstract":"Multiple osteoarticular tuberculosis (MOT) represents an uncommon yet severe form of tuberculosis, characterized by a lack of systematic analysis and comprehension. Our objective was to delineate MOT's epidemiological characteristics and establish a scientific foundation for prevention and treatment. We conducted searches across eight databases to identify relevant articles. Pearson's chi-square test (Fisher's exact test) and Bonferroni method were employed to assess osteoarticular involvement among patients of varying age and gender (α = 0.05). The study comprised 98 articles, encompassing 151 cases from 22 countries, with China and India collectively contributing 67.55% of cases. MOT predominantly affected individuals aged 0-30 years (58.94%). Pulmonary tuberculosis was evident in 16.55% of cases, with spinal involvement prevalent (57.62%). Significant differences were noted in trunk, spine, thoracic, and lumbar vertebrae involvement, as well as type I lesions across age groups, increasing with age. Moreover, significant differences were observed in upper limb bone involvement and type II lesions across age groups, decreasing with age. Gender differences were not significant. MOT primarily manifests in China and India, predominantly among younger individuals, indicating age-related variations in osteoarticular involvement. Enhanced clinical awareness is crucial for accurate MOT diagnosis, mitigating missed diagnoses and misdiagnoses.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e26"},"PeriodicalIF":2.5,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Queensland JEV vaccine program response to the 2022 Australian outbreak - CORRIGENDUM. 对昆士兰州乙脑病毒疫苗计划应对2022年澳大利亚疫情的评估-勘误表。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-01-17 DOI: 10.1017/S0950268825000019

Angus Misan, Stephen B Lambert, Hai Phung, Megan K Young

引用次数: 0

Antimicrobial resistance profiles and molecular epidemiology of Klebsiella pneumoniae isolates from Scottish bovine mastitis cases. 苏格兰牛乳腺炎肺炎克雷伯菌分离株的抗微生物药物耐药性和分子流行病学。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-01-17 DOI: 10.1017/S0950268824001754

Jolinda Pollock, Geoffrey Foster, Katrina Henderson, Jennifer Bell, Michael R Hutchings, Gavin K Paterson

{"title":"Antimicrobial resistance profiles and molecular epidemiology of Klebsiella pneumoniae isolates from Scottish bovine mastitis cases.","authors":"Jolinda Pollock, Geoffrey Foster, Katrina Henderson, Jennifer Bell, Michael R Hutchings, Gavin K Paterson","doi":"10.1017/S0950268824001754","DOIUrl":"10.1017/S0950268824001754","url":null,"abstract":"Klebsiella pneumoniae are opportunistic pathogens which can cause mastitis in dairy cattle. K. pneumoniae mastitis often has a poor cure rate and can lead to the development of chronic infection, which has an impact on both health and production. However, there are few studies which aim to fully characterize K. pneumoniae by whole-genome sequencing from bovine mastitis cases. Here, K. pneumoniae isolates associated with mastitis in dairy cattle were identified using matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF MS) and whole-genome sequencing. Furthermore, whole-genome sequence data were used for phylogenetic analyses and both virulence and antimicrobial resistance (AMR) prediction, in parallel with phenotypic AMR testing. Forty-two isolates identified as K. pneumoniae were subject to whole-genome sequencing, with 31 multi-locus sequence types being observed, suggesting the source of these isolates was likely environmental. Isolates were examined for key virulence determinants encoding acquired siderophores, colibactin, and hypermucoidy. The majority of these were absent, except for ybST (encoding yersiniabactin) which was present in six isolates. Across the dataset, there were notable levels of phenotypic AMR against streptomycin (26.2%) and tetracycline (19%), and intermediate susceptibility to cephalexin (26.2%) and neomycin (21.4%). Of importance was the detection of two ESBL-producing isolates, which demonstrated multi-drug resistance to amoxicillin-clavulanic acid, streptomycin, tetracycline, cefotaxime, cephalexin, and cefquinome.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":"153 ","pages":"e15"},"PeriodicalIF":2.5,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge, attitudes, and practices towards vector-borne diseases in changing climate in Finland. 芬兰气候变化对病媒传播疾病的知识、态度和做法。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-01-15 DOI: 10.1017/S0950268824001468

Henna Mäkelä, Timothée Dub, J Pekka Nuorti, Jussi Sane

{"title":"Knowledge, attitudes, and practices towards vector-borne diseases in changing climate in Finland.","authors":"Henna Mäkelä, Timothée Dub, J Pekka Nuorti, Jussi Sane","doi":"10.1017/S0950268824001468","DOIUrl":"10.1017/S0950268824001468","url":null,"abstract":"With climate change, the geographic distribution of some VBDs has expanded, highlighting the need for adaptation, and managing the risks associated with emergence in new areas. We conducted a questionnaire survey on the knowledge, attitudes, and practices (KAP) about vector-borne diseases (VBDs) among sample of Finnish residents. The questions were scored and the level of KAP was determined based on scoring as poor, fair, good, or excellent. Binary logistic regression analysis was used to evaluate the associations of different KAP levels with sex, age, education, and possible previous VPD infection. We received 491/1995 (25%) responses across the country and detected generally good knowledge, but only fair practices towards VBDs. Sex and age of the respondents were most often significantly associated with the level of KAP (P > 0.05). Despite the generally good knowledge, we detected major gaps, especially regarding the distinction of tick-borne encephalitis and Lyme borreliosis (LB), risk of disease, and protective measures. Additionally, many respondents thought the vaccination protects against LB or tick bites. This calls for awareness raising on disease risk and prevention measures. With increasing cases and the effects of climate change, surveillance of VBDs communication to the general public should be strengthened.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":"153 ","pages":"e12"},"PeriodicalIF":2.5,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implementing national antimicrobial consumption in Latin America and the Caribbean: opportunities and lessons learned. 在拉丁美洲和加勒比实施国家抗微生物药物消费：机遇和经验教训。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-01-14 DOI: 10.1017/S0950268824001237

Gustavo Horacio Marin, Lucia Giangreco, Paola Lichtenberger, Cristian Dorati, Perla Mordujovich-Buschiazzo, Robin Rojas-Cortés, Pilar Ramón-Pardo, Danini Marín, José Luis Castro

{"title":"Implementing national antimicrobial consumption in Latin America and the Caribbean: opportunities and lessons learned.","authors":"Gustavo Horacio Marin, Lucia Giangreco, Paola Lichtenberger, Cristian Dorati, Perla Mordujovich-Buschiazzo, Robin Rojas-Cortés, Pilar Ramón-Pardo, Danini Marín, José Luis Castro","doi":"10.1017/S0950268824001237","DOIUrl":"10.1017/S0950268824001237","url":null,"abstract":"Surveillance of antimicrobial consumption (AMC) is essential to anticipate and inform policies and public health decisions to prevent and/or contain antimicrobial resistance (AMR). This manuscript shares the experience on AMC data collection in Latin American & Caribbean (LAC). The WHO GLASS-AMC methodology for AMC surveillance was used for data registration during the period 2019-2022. Focal points belonging to each country were contacted and trained for AMC source of information detection, managing registration tools, and data analysis. Thirteen countries were enrolled with significant heterogeneity in the AMC results (range 2.55-36.26 DID-AMC). This experience reflects the heterogeneity of realities in LAC countries; how each one of the nations selected the best sources to collect AMC data, which were the main problems in applying the WHO-AMC collection tool, and the approach that each country gave to the analysis of its data. Finally, some examples are provided on the use of AMC information in making the best decision-making related to AMR control policies at the national level.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":"153 ","pages":"e11"},"PeriodicalIF":2.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11736441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142978134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends in general practitioner consultations for hand foot and mouth disease in England between 2017 and 2022. 2017年至2022年英国手足口病全科医生咨询趋势

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-01-13 DOI: 10.1017/S095026882400181X

Natalia G Bednarska, Sue Smith, Megan Bardsley, Paul Loveridge, Rachel Byford, William H Elson, Helen E Hughes, Simon de Lusignan, Daniel Todkill, Alex J Elliot

{"title":"Trends in general practitioner consultations for hand foot and mouth disease in England between 2017 and 2022.","authors":"Natalia G Bednarska, Sue Smith, Megan Bardsley, Paul Loveridge, Rachel Byford, William H Elson, Helen E Hughes, Simon de Lusignan, Daniel Todkill, Alex J Elliot","doi":"10.1017/S095026882400181X","DOIUrl":"10.1017/S095026882400181X","url":null,"abstract":"Hand, foot and mouth disease (HFMD) is a contagious communicable disease, with a high incidence in children aged under 10 years. It is a mainly self-limiting disease but can also cause serious neurological or cardiopulmonary complications in some cases, which can lead to death. Little is known about the burden of HMFD on primary care health care services in the UK. The aim of this work was to describe trends in general practitioner (GP) consultations for HFMD in England from January 2017 to December 2022 using a syndromic surveillance network of GPs. Daily GP consultations for HFMD in England were extracted from 1 January 2017 to 31 December 2022. Mean weekly consultation rates per 100,000 population and 95% confidence intervals (CI) were calculated. Consultation rates and rate ratios (RR) were calculated by age group and sex. During the study period, the mean weekly consultation rate for HFMD (per 100,000 registered GP patients) was 1.53 (range of 0.27 to 2.47). In England, children aged 1-4 years old accounted for the largest affected population followed by children <1 years old. We observed a seasonal pattern of HFMD incidence during the non-COVID years, with a seasonal peak of mean weekly rates between months of September and December. HFMD is typically diagnosed clinically rather than through laboratory sampling. Therefore, the ability to look at the daily HFMD consultation rates provides an excellent epidemiological overview on disease trends. The use of a novel GP-in-hours surveillance system allowed a unique epidemiological insight into the recent trends of general practitioner consultations for HFMD. We demonstrate a male predominance of cases, the impact of the non-pharmaceutical interventions during the COVID-19 pandemic, and a change in the week in which the peak number of cases happens post-pandemic.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e22"},"PeriodicalIF":2.5,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hepatitis E virus (HEV) infection among the Arab population in Northern Israel: an insight into the seroepidemiology and associated risk factors. 以色列北部阿拉伯人口中的戊型肝炎病毒（HEV）感染：对血清流行病学和相关危险因素的了解

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-01-13 DOI: 10.1017/S0950268824001407

Orna Mor, Wasef Na'amnih, Rachel Shirazi, Marina Wax, Yael Gozlan, Marah Kassim, Helal Sayid, Ali Omari, Adel Jabbor, Khitam Muhsen, Amir Mari

{"title":"Hepatitis E virus (HEV) infection among the Arab population in Northern Israel: an insight into the seroepidemiology and associated risk factors.","authors":"Orna Mor, Wasef Na'amnih, Rachel Shirazi, Marina Wax, Yael Gozlan, Marah Kassim, Helal Sayid, Ali Omari, Adel Jabbor, Khitam Muhsen, Amir Mari","doi":"10.1017/S0950268824001407","DOIUrl":"10.1017/S0950268824001407","url":null,"abstract":"Hepatitis E virus (HEV) is one of the most common causes of viral hepatitis. We examined HEV seroprevalence and associations of sociodemographic and lifestyle characteristics with HEV immunoglobulin G (IgG) seropositivity in the Arab population. A cross-sectional single-centre study was conducted among adults in the Nazareth area during 2022. Blood samples were tested using the Altona Real-Star HEV-RNA and the Wantai IgG assays. Data on sociodemographics, health status, and lifestyle were collected using structured questionnaires.Overall, 490 individuals (55.9% males) aged 18 - 96 (mean = 53.2, SD = 28.0) were enrolled. HEV IgG seropositivity was estimated at 21.4% (95% CI 17.9-25.3). No samples were HEV-RNA positive. The correlates of HEV IgG seropositivity were older age (prevalence ratio (PR) 1.07, 95% CI 1.04-1.09, P < 0.001) and consuming beef frequently (PR 2.81, 95% CI 1.40-5.63, P = 0.003). No associations were found between Arab religious groups (Muslim, Christian or Druze, representing different socioeconomic status and dietary habits) or pork consumption and HEV IgG seropositivity. In conclusion, HEV seropositivity was high in the Arab population, and assessing HEV in Ruminants, particularly cows, is warranted.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":"153 ","pages":"e10"},"PeriodicalIF":2.5,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11729521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0