Neil Franklin, Kirsty Hope, Kathryn Glass, Martyn Kirk
{"title":"Text message surveillance for rapid <i>Salmonella</i> outbreak detection: a novel public health approach.","authors":"Neil Franklin, Kirsty Hope, Kathryn Glass, Martyn Kirk","doi":"10.1017/S0950268825100617","DOIUrl":"https://doi.org/10.1017/S0950268825100617","url":null,"abstract":"","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"1-18"},"PeriodicalIF":2.2,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145184996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katherine Robsky, Annet Nalutaaya, Peter James Kitonsa, James Mukiibi, David Isooba, Olga Nakasolya, Emily A Kendall, Jonathan Zelner, Jennifer M Ross, Achilles Katamba, David Dowdy
{"title":"The potential yield of geographically targeted tuberculosis contact investigation in urban Uganda.","authors":"Katherine Robsky, Annet Nalutaaya, Peter James Kitonsa, James Mukiibi, David Isooba, Olga Nakasolya, Emily A Kendall, Jonathan Zelner, Jennifer M Ross, Achilles Katamba, David Dowdy","doi":"10.1017/S0950268825100605","DOIUrl":"https://doi.org/10.1017/S0950268825100605","url":null,"abstract":"","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"1-8"},"PeriodicalIF":2.2,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sofie Gillesberg Lassen, Christina Poethko-Müller, Martin Schlaud, Heiko Slanina, Christian G Schüttler, Klaus Stark, Viviane Bremer, Thomas Harder, Sandra Dudareva
{"title":"Evidence of very low hepatitis B virus prevalence in children and adolescents, Germany: national cross-sectional study, 2014-2017.","authors":"Sofie Gillesberg Lassen, Christina Poethko-Müller, Martin Schlaud, Heiko Slanina, Christian G Schüttler, Klaus Stark, Viviane Bremer, Thomas Harder, Sandra Dudareva","doi":"10.1017/S0950268825100563","DOIUrl":"https://doi.org/10.1017/S0950268825100563","url":null,"abstract":"","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"1-23"},"PeriodicalIF":2.2,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Hossein Ahmadi, Zeinab Fagheei Aghmiyuni, Shahriar Bakhti
{"title":"Worldwide threatening prevalence of carbapenem-resistant <i>Pseudomonas aeruginosa</i>.","authors":"Mohammad Hossein Ahmadi, Zeinab Fagheei Aghmiyuni, Shahriar Bakhti","doi":"10.1017/S0950268825100332","DOIUrl":"10.1017/S0950268825100332","url":null,"abstract":"<p><p>β-Lactam/β-lactamase inhibitor combinations and carbapenems are the first-line treatments for multidrug-resistant <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) infections. However, carbapenem resistance is increasing globally at an alarming rate, which is especially concerning given the pivotal role of these agents. This study comprehensively evaluated the global distribution of carbapenem resistance in clinical <i>P. aeruginosa</i> isolates. The keywords including '<i>Pseudomonas', P. aeruginosa'</i>, '<i>P. aeruginosa'</i>, 'resistance', 'susceptibility', 'carbapenem antibiotics', 'carbapenems', 'imipenem', 'meropenem', 'ertapenem', 'doripenem', as well as 'prevalence' and 'incidence' were searched in electronic databases as the appropriate keywords. After screening, 160 studies were excluded, with 87 eligible studies from diverse geographic regions retained for final analysis. A comprehensive meta-analysis was then conducted on the data collected. The mean resistance rates (95% CI) were 33.3% (imipenem), 23.3% (meropenem), 60.9% (ertapenem), and 36.7% (doripenem). The time trend analysis showed that the resistance to meropenem has increased from the year 1997 to 2023. Meta-analysis showed substantial heterogeneity (I<sup>2</sup> = 92%, p < 0.05) but no significant publication bias by Egger's or Begg's test. Global carbapenem resistance is alarmingly high in clinical <i>P. aeruginosa</i> isolates. The increasing prevalence of carbapenem-resistant <i>P. aeruginosa</i> is a major global health threat requiring urgent action through new antimicrobials and improved antibiotic stewardship to protect these last-line drugs.</p>","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e114"},"PeriodicalIF":2.2,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145085384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bastiaan Van der Roest, Egil A J Fischer, Don Klinkenberg, Martin C J Bootsma, Mojca Maticic, Katarina Resman-Rus, Miša Korva, Tatjana Avsic-Zupanc, Mirjam Kretzschmar
{"title":"Phylodynamic inference suggests introductions as main driver of Mpox Clade II outbreak in 2022 in Slovenia.","authors":"Bastiaan Van der Roest, Egil A J Fischer, Don Klinkenberg, Martin C J Bootsma, Mojca Maticic, Katarina Resman-Rus, Miša Korva, Tatjana Avsic-Zupanc, Mirjam Kretzschmar","doi":"10.1017/S0950268825100587","DOIUrl":"https://doi.org/10.1017/S0950268825100587","url":null,"abstract":"","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"1-15"},"PeriodicalIF":2.2,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145085441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mulu Woldegiorgis, Lauren Bloomfield, Rosemary Korda, Gemma Cadby, Sera Ngeh, Paul Knight, Andrew Jardine, Jelena Maticevic, Paul Armstrong, Paul Effler
{"title":"Factors associated with persistence or recovery from long COVID six months post SARS-CoV-2 infection.","authors":"Mulu Woldegiorgis, Lauren Bloomfield, Rosemary Korda, Gemma Cadby, Sera Ngeh, Paul Knight, Andrew Jardine, Jelena Maticevic, Paul Armstrong, Paul Effler","doi":"10.1017/S0950268825100551","DOIUrl":"https://doi.org/10.1017/S0950268825100551","url":null,"abstract":"","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"1-18"},"PeriodicalIF":2.2,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145079419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of influencing factors of concurrent primary liver cancer in hepatitis B patients and construction of column chart prediction model.","authors":"Qunmei Cao, Yilin Zhou, Changlong Wen, Qinglan Li","doi":"10.1017/S0950268825100538","DOIUrl":"10.1017/S0950268825100538","url":null,"abstract":"<p><p>A predictive column chart was developed to assess the risk of primary liver cancer (PLC) in hepatitis B patients. Data from 107 PLC patients and 107 controls were used as the training set, with 92 patients as the validation set. An additional 446 patients from other hospitals, including 15 with PLC, formed the external validation group. Multivariate logistic regression identified gender, BMI, alcohol consumption, diabetes, family history of liver cancer, cirrhosis, and HBV DNA load as independent risk factors. The model showed strong discrimination with AUCs of 0.882 and 0.859 in the training and validation sets, respectively, and good calibration (Hosmer-Lemeshow χ² = 2.648, P = 0.954; χ² = 4.117, P = 0.846). Decision curve analysis (DCA) confirmed clinical benefit within a risk threshold of 0.07-0.95. In the external validation group, the model maintained discrimination (AUC = 0.863) and calibration (Hosmer-Lemeshow χ² = 7.999, P = 0.434), with DCA showing net benefit across 0.14-0.95. These results indicate the column chart is a reliable tool for PLC risk prediction in hepatitis B patients.</p>","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e111"},"PeriodicalIF":2.2,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145069361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aman Ullah, Dorte Frees, Mujahida Mansoor, Shah Faisal Jamal, Jan Tkadlec
{"title":"Multiple highly resistant clones of MRSA circulating among patients with skin and soft tissue infection, Peshawar, Pakistan 2021-2022.","authors":"Aman Ullah, Dorte Frees, Mujahida Mansoor, Shah Faisal Jamal, Jan Tkadlec","doi":"10.1017/S0950268825100575","DOIUrl":"10.1017/S0950268825100575","url":null,"abstract":"<p><p>We aimed to determine the prevalence of antimicrobial resistance, carriage of Panton-Valentine leucocidin (PVL), and the clonal structure of MRSA isolates collected from skin and soft tissue infections at a tertiary care hospital in Pakistan. Between August 2021 and May 2022, 154 non-repetitive MRSA isolates were consecutively collected and characterized by antimicrobial susceptibility testing, SCC<i>mec</i> typing, <i>spa</i> typing, and detection of PVL by PCR. MLST clonal complexes (CCs) were inferred from <i>spa</i> type using the Based Upon Repeat Pattern (BURP) algorithm. High levels of resistance were observed to ciprofloxacin (85.7%), erythromycin (76.0%), sulfamethoxazole (68.8%), gentamicin (68.8%), fusidic acid (57.8%), tetracycline (55.8%), and clindamycin (42.2%). Clonal analysis revealed 16 lineages, with the most frequent being CC8-MRSA-IV (27.3%), PVL-positive \"Bengal Bay\" CC1/ST772-MRSA-V (26.0%), and CC1-MRSA-IV (16.2%). PVL was detected in 45.5% of isolates across multiple lineages. Our findings highlight the coexistence of high antimicrobial resistance and frequent PVL carriage among MRSA in Pakistan. Given the association of PVL with severe infections and the limited treatment options for multidrug-resistant strains, these data underscore a significant public health concern and the need for systematic surveillance and prudent antibiotic use.</p>","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e113"},"PeriodicalIF":2.2,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145069371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara R Healy, Martha Betson, Joaquin M Prada, Eric R Morgan
{"title":"Response to letter to editor from Rattanapitoon, N. & Rattanapitoon, S.","authors":"Sara R Healy, Martha Betson, Joaquin M Prada, Eric R Morgan","doi":"10.1017/S0950268825100459","DOIUrl":"10.1017/S0950268825100459","url":null,"abstract":"","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":"153 ","pages":"e100"},"PeriodicalIF":2.2,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12455500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor: \"Modelling the risk of foodborne transmission of Toxocara spp. to humans\" by Healy et al. (2025).","authors":"Nathkapach Kaewpitoon Rattanapitoon, Schawanya Kaewpitoon Rattanapitoon","doi":"10.1017/S0950268825100447","DOIUrl":"10.1017/S0950268825100447","url":null,"abstract":"","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":"153 ","pages":"e101"},"PeriodicalIF":2.2,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12455503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}