Epidemiology and Infection最新文献_第2页

Factors associated with carditis adverse events following SARS-COV-2-19 vaccination. 与SARS-COV-2-19疫苗接种后心炎不良事件相关的因素

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-03-19 DOI: 10.1017/S0950268825000329

Kyung Hyun Min, Jun Hyeob Kim, Jin Yeon Gil, Jun Hyuk Park, Ji Min Han, Kyung Eun Lee

{"title":"Factors associated with carditis adverse events following SARS-COV-2-19 vaccination.","authors":"Kyung Hyun Min, Jun Hyeob Kim, Jin Yeon Gil, Jun Hyuk Park, Ji Min Han, Kyung Eun Lee","doi":"10.1017/S0950268825000329","DOIUrl":"10.1017/S0950268825000329","url":null,"abstract":"The study aimed to delve into the incidence and risk factors associated with myocarditis and pericarditis following SARS-COV-2-19 vaccination, addressing a notable gap in understanding the safety profile of vaccinations. Through meticulous data selection from the National Health Insurance System (NHIS) database of Korea, the researchers employed both a case-crossover study and a nested case-control design to analyze temporal patterns and risk factors related to carditis occurrences post-immunization. Key findings revealed a significant association between SARS-COV-2-19 vaccination and the occurrence of carditis, with a strong temporal correlation observed within 10 days post-vaccination. Noteworthy factors contributing to carditis risk included the duration between vaccination and carditis, specific comorbidities and medication use. The study concluded by recommending an extended post-vaccination surveillance duration of at least 10 days and underscored the importance of considering individual medical histories and concurrent medication use in assessing vaccine-induced carditis risk. This study might contribute to understanding vaccine safety profiles and emphasizes the significance of comprehensive post-vaccination monitoring protocols.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e51"},"PeriodicalIF":2.5,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A new approach to define the optimal immunization strategy against pneumococcal disease: the example of Canada. 确定肺炎球菌疾病最佳免疫策略的新方法：以加拿大为例。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-03-19 DOI: 10.1017/S0950268825000305

Philippe De Wals

{"title":"A new approach to define the optimal immunization strategy against pneumococcal disease: the example of Canada.","authors":"Philippe De Wals","doi":"10.1017/S0950268825000305","DOIUrl":"10.1017/S0950268825000305","url":null,"abstract":"New-generation pneumococcal conjugate vaccines (PCVs) are available to replace PCV-13 for childhood and adult immunization. Besides cost-effectiveness evaluations which have highly variable results, the comparative immunogenicity of these new vaccines (PCV15, PCV20, PCV21) and their coverage of invasive pneumococcal disease (IPD) and carriage strains in different age-groups should be regarded as well as the antibody susceptibility, antibiotic resistance, invasiveness and virulence of serotypes included in each vaccine. Based on the Canadian experience, these topics are discussed. The optimal strategy would be a 2+1 PCV20 schedule for children, PCV21 for elderly adults and a dual PCV20+PCV21 schedule for adults at very high IPD risk. Shifting from PCV-13 to PCV-15 for children entails a risk of increased IPD incidence in adults because additional serotypes are of low virulence and could be replaced by more invasive and virulent serotypes. This risk can be reasonably excluded if PCV-20 replaces PCV-13 as the former covers additional serotypes being highly invasive and virulent. It is recognized that off-label use of PCV-20 according to a 2+1 schedule could be problematic for some jurisdictions as this is not authorized in all countries. In Canada, however, the 2+1 PCV20 schedule was authorized based on the same dataset submitted elsewhere.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":"153 ","pages":"e55"},"PeriodicalIF":2.5,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of two methods for the estimation of COVID-19 vaccine effectiveness of the autumnal booster within the VEBIS-EHR network in 2022/23. 2022/23年VEBIS-EHR网络秋季强化剂COVID-19疫苗有效性评估两种方法的比较

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-03-17 DOI: 10.1017/S0950268825000317

Susana Monge, James Humphreys, Nathalie Nicolay, Toon Braeye, Izaak Van Evercooren, Christian Holm Hansen, Hanne-Dorthe Emborg, Massimo Fabiani, Chiara Sacco, Jesús Castilla, Iván Martínez-Baz, Brechje de Gier, Susan Hahné, Hinta Meijerink, Anja Bråthen Kristoffersen, Ausenda Machado, Patricia Soares, Mario Fontán-Vela, Anthony Nardone, Esther Kissling, Baltazar Nunes

{"title":"Comparison of two methods for the estimation of COVID-19 vaccine effectiveness of the autumnal booster within the VEBIS-EHR network in 2022/23.","authors":"Susana Monge, James Humphreys, Nathalie Nicolay, Toon Braeye, Izaak Van Evercooren, Christian Holm Hansen, Hanne-Dorthe Emborg, Massimo Fabiani, Chiara Sacco, Jesús Castilla, Iván Martínez-Baz, Brechje de Gier, Susan Hahné, Hinta Meijerink, Anja Bråthen Kristoffersen, Ausenda Machado, Patricia Soares, Mario Fontán-Vela, Anthony Nardone, Esther Kissling, Baltazar Nunes","doi":"10.1017/S0950268825000317","DOIUrl":"10.1017/S0950268825000317","url":null,"abstract":"Within an infrastructure to monitor vaccine effectiveness (VE) against hospitalization due to COVID-19 and COVID-19 related deaths from November 2022 to July 2023 in seven countries in real-world conditions (VEBIS network), we compared two approaches: (a) estimating VE of the first, second or third COVID-19 booster doses administered during the autumn of 2022, and (b) estimating VE of the autumn vaccination dose regardless of the number of prior doses (autumnal booster approach). Retrospective cohorts were constructed using Electronic Health Records at each participating site. Cox regressions with time-changing vaccination status were fit and site-specific estimates were combined using random-effects meta-analysis. VE estimates with both approaches were mostly similar, particularly shortly after the start of the vaccination campaign, and showed a similar timing of VE waning. However, autumnal booster estimates were more precise and showed a clearer trend, particularly compared to third booster estimates, as calendar time increased after the vaccination campaign and during periods of lower SARS-CoV-2 activity. Moreover, the decrease in protection by increasing calendar time was more clear and precise than when comparing protection by number of doses. Therefore, estimating VE under an autumnal booster framework emerges as a preferred method for future monitoring of COVID-19 vaccination campaigns.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e54"},"PeriodicalIF":2.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Data for action - description of the automated COVID-19 surveillance system in Denmark and lessons learnt, January 2020 to June 2024. 行动数据 - 2020 年 1 月至 2024 年 6 月丹麦 COVID-19 自动监测系统说明及经验教训。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-03-14 DOI: 10.1017/S0950268825000263

Gudrun Witteveen-Freidl, Karina Lauenborg Møller, Marianne Voldstedlund, Sophie Gubbels

{"title":"Data for action - description of the automated COVID-19 surveillance system in Denmark and lessons learnt, January 2020 to June 2024.","authors":"Gudrun Witteveen-Freidl, Karina Lauenborg Møller, Marianne Voldstedlund, Sophie Gubbels","doi":"10.1017/S0950268825000263","DOIUrl":"10.1017/S0950268825000263","url":null,"abstract":"Denmark is one of the leading countries in establishing digital solutions in the health sector. When SARS-CoV-2 arrived in February 2020, a real-time surveillance system could be rapidly built on existing infrastructure, This rapid data integration for COVID-19 surveillance enabled a data-driven response. Here we describe (a) the setup of the automated, real-time surveillance and vaccination monitoring system for COVID-19 in Denmark, including primary stakeholders, data sources, and algorithms, (b) describe outputs for various stakeholders, (c) how outputs were used for action and (d) reflect on challenges and lessons learnt. Outputs were tailored to four main stakeholder groups: four outputs provided direct information to individual citizens, four to complementary systems and researchers, 25 to decision-makers, and 15 informed the public, aiding transparency. Core elements in infrastructure needed for automated surveillance had been in place for more than a decade. The COVID-19 epidemic was a pressure test that allowed us to explore the system's potential and identify challenges for future pandemic preparedness. The system described here constitutes a model for the future infectious disease surveillance in Denmark. With the current pandemic threat posed by avian influenza viruses, lessons learnt from the COVID-19 pandemic remain topical and relevant.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e58"},"PeriodicalIF":2.5,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Increasing incidence of invasive group A streptococcal (iGAS) outbreaks in England 2015-2019. 2015-2019年英格兰侵袭性A组链球菌（iGAS）暴发的发病率增加。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-03-12 DOI: 10.1017/S0950268825000226

Iona Smith, Elizabeth Marchant, Juliana Coelho, Megan Bardsley, Amanda Wright, Nicola Love, Sooria Balasegaram, Colin S Brown, Dan Todkill, Theresa Lamagni, Valérie Decraene

引用次数: 0

First nationwide case - case study on factors associated with emerging methicillin-resistant Staphylococcus aureus spa type t4549 in Denmark, 2022-2023. 2022-2023年丹麦首次出现耐甲氧西林金黄色葡萄球菌spa型t4549相关因素的全国性个案研究

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-03-12 DOI: 10.1017/S0950268825000299

Johanna J Young, Tjede Funk, Tinna Ravnholt Urth, Steen Ethelberg, Jesper Larsen, Andreas Petersen

{"title":"First nationwide case - case study on factors associated with emerging methicillin-resistant Staphylococcus aureus spa type t4549 in Denmark, 2022-2023.","authors":"Johanna J Young, Tjede Funk, Tinna Ravnholt Urth, Steen Ethelberg, Jesper Larsen, Andreas Petersen","doi":"10.1017/S0950268825000299","DOIUrl":"10.1017/S0950268825000299","url":null,"abstract":"Methicillin-resistant Staphylococcus aureus (MRSA) spa type t4549 is increasingly prevalent in Denmark, yet its epidemiological sources remain unclear. This study aimed to generate hypotheses about possible risk factors that may be associated with MRSA t4549 infections. We conducted a nationwide case - case questionnaire study comparing MRSA t4549 cases to other MRSA types (t002, t008, t127, t304, and t223) reported between January 2022 and November 2023. The analysis, which included descriptive statistics and logistic regression, found that 75% of MRSA t4549 cases were male. Infections were significantly more frequent in the foot (28%) and toe (54%) compared to other MRSA types. Key risk factors identified were contact with pheasants (OR = 8.70; 95%CI 1.25-174.29), participation in indoor team sports (OR = 7.54, 95%CI: 1.58-54.82) and swimming (OR = 4.15, 95%CI: 1.97-9.03). Although the limited number of cases warrants cautious interpretation, it is crucial to emphasize the need for preventive measures at both the individual and sports facility levels. Further environmental studies are needed to clarify the role of the environment and wildlife in MRSA t4549 transmission. The increasing prevalence of this spa type in Denmark underlines the importance of implementing effective public health strategies to reduce the risk of MRSA transmission.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e52"},"PeriodicalIF":2.5,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The evolution and epidemiology of H3N2 canine influenza virus after 20 years in dogs. 犬h3n2型流感病毒20年来的演变及流行病学研究。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-03-05 DOI: 10.1017/S0950268825000251

Brian R Wasik, Lambodhar Damodaran, Maria A Maltepes, Ian E H Voorhees, Christian M Leutenegger, Sandra Newbury, Louise H Moncla, Benjamin D Dalziel, Laura B Goodman, Colin R Parrish

{"title":"The evolution and epidemiology of H3N2 canine influenza virus after 20 years in dogs.","authors":"Brian R Wasik, Lambodhar Damodaran, Maria A Maltepes, Ian E H Voorhees, Christian M Leutenegger, Sandra Newbury, Louise H Moncla, Benjamin D Dalziel, Laura B Goodman, Colin R Parrish","doi":"10.1017/S0950268825000251","DOIUrl":"10.1017/S0950268825000251","url":null,"abstract":"The H3N2 canine influenza virus (CIV) emerged from an avian reservoir in Asia to circulate entirely among dogs for the last 20 years. The virus was first seen circulating outside Asian dog populations in 2015, in North America. Utilizing viral genomic data in addition to clinical reports and diagnostic testing data, we provide an updated analysis of the evolution and epidemiology of the virus in its canine host. CIV in dogs in North America is marked by a complex life history - including local outbreaks, regional lineage die-outs, and repeated reintroductions of the virus (with diverse genotypes) from different regions of Asia. Phylogenetic and Bayesian analysis reveal multiple CIV clades, and viruses from China have seeded recent North American outbreaks, with 2 or 3 introductions in the past 3 years. Genomic epidemiology confirms that within North America the virus spreads very rapidly among dogs in kennels and shelters in different regions - but then dies out locally. The overall epidemic therefore requires longer-distance dispersal of virus to maintain outbreaks over the long term. With a constant evolutionary rate over 20 years, CIV still appears best adapted to transmission in dense populations and has not gained properties for prolonged circulation among dogs.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e47"},"PeriodicalIF":2.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiologic profile of community-acquired Clostridioides difficile infections: a systematic review and meta-analysis. 社区获得性艰难梭菌感染的流行病学概况：系统回顾和荟萃分析。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-03-04 DOI: 10.1017/S0950268825000202

Neri Alejandro Álvarez-Villalobos, Fernando Gerardo Ruiz-Hernandez, Ana Camila Méndez-Arellano, Jhoan Manuel Azamar-Márquez, Adrián Camacho-Ortiz

{"title":"Epidemiologic profile of community-acquired Clostridioides difficile infections: a systematic review and meta-analysis.","authors":"Neri Alejandro Álvarez-Villalobos, Fernando Gerardo Ruiz-Hernandez, Ana Camila Méndez-Arellano, Jhoan Manuel Azamar-Márquez, Adrián Camacho-Ortiz","doi":"10.1017/S0950268825000202","DOIUrl":"10.1017/S0950268825000202","url":null,"abstract":"Clostridiodes difficile's epidemiology has evolved over the past decades, being recognized as an important cause of disease in the community setting. Even so, there has been heterogeneity in the reports of CA-CDI. Therefore, the aim of this study was to assess the epidemiologic profile of CA-CDI.This systematic review and meta-analysis were conducted according to PRISMA checklist and Cochrane guidelines (CRD42023451134). Literature search was performed by an experienced librarian from inception to April 2023, searching in databases like MEDLINE, Scopus, Web of Science, EMBASE, CCRCC, CDSR, and ClinicalTrials. Observational studies that reported prevalence, incidence of CA-CDI, or indicators to calculate them were included. Pool analysis was performed using a binomial-normal model via the generalized linear mixed model. Subgroup analysis and publication bias were also explored. A total of 49 articles were included, obtaining a prevalence of 5% (95% CI 3-8) and an incidence of 7.53 patients (95% CI 4.45-12.74) per 100,000 person-years.In conclusion, this meta-analysis underscores that among the included studies, the prevalence of CA-CDI stands at 5%, with an incidence rate of 7.3 cases per 100,000 person-years. Noteworthy risk factors identified include prior antibiotic exposure and age.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e46"},"PeriodicalIF":2.5,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bartonella tracing in wild rodents in northwestern Mexico. 墨西哥西北部野生啮齿动物巴尔通体追踪。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-02-28 DOI: 10.1017/S0950268825000238

Adriana M Fernández-González, Andrés M López-Pérez, Angel Herrera-Mares, Andrea Chaves, Fabiola Ramírez-Corona, Gerardo Suzán

{"title":"Bartonella tracing in wild rodents in northwestern Mexico.","authors":"Adriana M Fernández-González, Andrés M López-Pérez, Angel Herrera-Mares, Andrea Chaves, Fabiola Ramírez-Corona, Gerardo Suzán","doi":"10.1017/S0950268825000238","DOIUrl":"10.1017/S0950268825000238","url":null,"abstract":"Bartonella is a widely distributed Gram-negative bacterium that includes species that are capable of causing illness in humans. Rodents represent one of the main reservoirs of zoonotic pathogens, and monitoring their populations can provide valuable insights into human health. We conducted a surveillance study of rodents from two north-western states of Mexico (Baja California and Chihuahua) to investigate the prevalence and genetic diversity of Bartonella by polymerase chain reaction (PCR) amplification and sequencing of the citrate synthase (gltA) gene. A total of 586 rodents belonging to 28 species were captured, and 408 were tested for Bartonella spp. The overall Bartonella spp. prevalence was 39.71%. The prevalence found in Chihuahua was higher (42.80%) than in Baja California (32.52%), and rodents such as Neotoma albigula, Neotoma mexicana, Peromyscus boylii, and Chaetodipus baileyi had the highest prevalence. The gltA sequences revealed seven genetic variants, some of which were obtained from Peromyscus and Dipodomys rodents and were associated with Bartonella species of human health concern, such as B. grahamii and B. vinsonii subsp. arupensis. In addition, a sequence obtained from a Peromyscus maniculatus was clustered with Candidatus Bartonella rudakovii, a previously unreported association. This study provides valuable data and new insight into the Bartonella-hosts interactions in rodent species in north-western Mexico.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e42"},"PeriodicalIF":2.5,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transmission of Mycobacterium tuberculosis in four prisons in Colombia. 哥伦比亚四所监狱中结核分枝杆菌的传播。

IF 2.5 4区医学

Epidemiology and Infection Pub Date : 2025-02-24 DOI: 10.1017/S0950268825000184

Zulma Vanessa Rueda, Mariana Herrera-Diaz, Diana Marin, Lucelly Lopez, Teresa Realpe, Laura Maria Almeida-Rueda, Luisa Arroyave, Nestor Rueda, Gloria Isabel Niño-Cruz, Uriel Hurtado, Nataly Alvarez, Yoav Keynan, Maria Patricia Arbelaez

{"title":"Transmission of Mycobacterium tuberculosis in four prisons in Colombia.","authors":"Zulma Vanessa Rueda, Mariana Herrera-Diaz, Diana Marin, Lucelly Lopez, Teresa Realpe, Laura Maria Almeida-Rueda, Luisa Arroyave, Nestor Rueda, Gloria Isabel Niño-Cruz, Uriel Hurtado, Nataly Alvarez, Yoav Keynan, Maria Patricia Arbelaez","doi":"10.1017/S0950268825000184","DOIUrl":"10.1017/S0950268825000184","url":null,"abstract":"Our study aimed to describe the transmission dynamics and genotypic diversity of Mycobacterium tuberculosis in people deprived of liberty (PDL) in four Colombian prisons. Our cohort study included 64 PDL with bacteriologically confirmed pulmonary tuberculosis diagnosed in four Colombian prisons. The 132 isolates were genotyped using 24-mycobacterial interspersed repeated units-variable number tandem repeats (MIRUs-VNTR). A cluster was defined when ≥2 isolates from different PDL had the same genotype. Tuberculosis acquired in prison was considered when ≥2 persons were within the same cluster and had an epidemiological link. We mapped the place of residence before incarceration and within prisons. We assessed overcrowding and ventilation conditions in the prison that had clusters. We found that the most frequent genotypes were LAM (56.8%) and Haarlem (36.4%), and 45.3% of the PDL diagnosed with tuberculosis were clustered. Most PDL diagnosed in prison came from neighborhoods in Medellin with a high TB incidence. M. tuberculosis infection acquired in prison was detected in 19% of PDL, 9.4% had mixed infection, 3.1% reinfection, and 1.6% relapse. Clusters only appeared in one prison, in cell blocks with overcrowding >100%, and inadequate ventilation conditions. Prisons require the implementation of effective respiratory infection control measures to prevent M. tuberculosis transmission.","PeriodicalId":11721,"journal":{"name":"Epidemiology and Infection","volume":" ","pages":"e43"},"PeriodicalIF":2.5,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0