Early Intervention in Psychiatry最新文献

{"title":"Uncertainty Mentalizing and Emotion Dysregulation With Substance Use Severity in Iranian Young Adults; Mediating Role of Borderline Personality Traits","authors":"Mehdi Azad,&nbsp;Farhad Taremian,&nbsp;Shima Shakiba","doi":"10.1111/eip.70040","DOIUrl":"https://doi.org/10.1111/eip.70040","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The rising prevalence of substance use amongst young people (ages 18–25) is a critical global health issue, especially in non-Western contexts where cultural factors impact mental health. This study explores the role of uncertainty mentalizing—understanding ambiguous social situations—in individuals with borderline personality traits and its link to substance use, a relationship that remains underexplored amongst young Iranian people. It further examines the mediating role of borderline personality traits in the relationship between uncertainty mentalizing, emotion dysregulation and substance use severity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>The study included 185 people who use substances aged 18–25 years who completed questionnaires related to the research variables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Analysis Revealed Significant Positive Associations Amongst all Variables (<i>p</i> &lt; 0.001). Borderline Personality Traits (<i>β</i> = 0.19, <i>p</i> &lt; 0.05) and Uncertainty Mentalizing (<i>β</i> = 0.45, <i>p</i> &lt; 0.001) Directly Influenced Substance Use Severity. Uncertainty Mentalizing Also Indirectly Affected Substance Use Severity Through Borderline Personality Traits (Indirect Effect = 0.093, <i>p</i> &lt; 0.05) and Notably Impacted Borderline Personality Traits (<i>β</i> = 0.49, <i>p</i> &lt; 0.001). However, Emotion Dysregulation Did Not Show Significant Direct or Indirect Effects.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>These results highlight the critical role of uncertainty mentalizing in substance use severity, both directly and through its influence on borderline personality traits, suggesting that interventions aimed at enhancing uncertainty mentalizing may effectively address co-occurring issues related to substance use and borderline personality traits.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental Health of Indian Transgender Individuals: A Meta-Ethnography","authors":"Kumari Sarika,&nbsp;Devu Rajeev,&nbsp;Sucharita Maji,&nbsp;Gerald Jordan","doi":"10.1111/eip.70048","DOIUrl":"https://doi.org/10.1111/eip.70048","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Gender, as a social determinant of health, places transgender (TG) individuals at increased risk for mental health issues. This review aimed to explore the mental health challenges faced by Indian transgender individuals and the factors contributing to these challenges through an interpretative synthesis of existing qualitative research.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A meta-ethnographic approach was used to synthesise qualitative research on the mental health of transgender individuals in India. Ten studies were systematically identified, reviewed and analysed using Noblit and Hare's method (1988) of meta-ethnography.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Four major themes emerged from the synthesis: healthcare barriers, predisposing factors to psychological distress, mental health issues, and coping strategies. Within healthcare barriers, three sub-themes were identified: stigma and discrimination within the healthcare system, limited life resources for accessing services, and healthcare-system barriers. Predisposing factors emerged at micro (individual and familial), meso (community and organisational) and macro (societal and legal) levels, reflecting varied sources of distress. Mental health issues such as anxiety, depression, suicidality and substance use were reported.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Based on these findings, a model is developed to illustrate the interconnected factors affecting the mental health of Indian transgender individuals. The findings have important implications for improving healthcare, policy and mental health practices to better support transgender individuals.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143897224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased Prevalence of Childhood Complex Trauma in Comorbid Posttraumatic Stress Disorder and Substance Use Disorders Compared to Either Disorder Alone: A Systematic Review","authors":"Herry Patel,&nbsp;Bethany Easterbrook,&nbsp;Fiona A. Ralston,&nbsp;Daria Shariff,&nbsp;Haley Lester,&nbsp;Daniel Landaverde,&nbsp;Erika Lau,&nbsp;Isabella S. Davis,&nbsp;Isabel R. Aks,&nbsp;Sandra A. Brown,&nbsp;Susan F. Tapert,&nbsp;William E. Pelham III","doi":"10.1111/eip.70051","DOIUrl":"https://doi.org/10.1111/eip.70051","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Childhood complex trauma (CCT) prevalence among individuals with comorbid posttraumatic stress disorder (PTSD) and substance use disorder (SUD) is unknown. We conducted a meta-analysis to compare CCT prevalence in samples of PTSD alone, SUD alone and comorbid PTSD+SUD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A systematic review of PTSD, CCT and SUD literature was conducted using online databases. Binary outcome meta-analytic models were fitted comparing CCT prevalence in comorbid PTSD + SUD to PTSD and SUD only.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Seven studies were included, and estimates for CCT prevalence were higher, on average, among individuals with comorbid PTSD+SUD (35%–78%) compared to PTSD alone (4%–70%) and SUD alone (2%–65%). A meta-analysis of four studies indicated individuals with comorbid PTSD+SUD were 18% more likely to have experienced CCT compared to individuals with PTSD only (RR = 1.18, 95% CI [1.13, 1.25]) and 24% more likely compared to individuals with SUD only (RR = 1.24, 95% CI [1.20, 1.29]).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Further research is needed to establish a more accurate prevalence rate for individuals with comorbid PTSD and SUD. Evidence of greater CCT prevalence will inform research study design and clinical targets during treatment for individuals with comorbid PTSD and SUD.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of a School-Based Suicide Prevention Gatekeeper Intervention and an Implementation Intervention (Project ROS): Study Protocol","authors":"Lena Rossen Østergaard,&nbsp;Lotus Sofie Bast,&nbsp;Rory C. O'Connor,&nbsp;Erik Christiansen","doi":"10.1111/eip.70050","DOIUrl":"https://doi.org/10.1111/eip.70050","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Despite the high risk of suicidal behaviour in youth, there is a lack of evidence-based interventions within school settings for those who are at increased risk. The Project ROS (in Realise, Convince and Refer in Danish Realiser, Overbevis og Send videre) will train teaching staff and implement QPR (Question, Persuade, Refer), a suicide prevention gatekeeper intervention supported by an implementation intervention at specialised schools (FGU) in Denmark.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To determine the feasibility of delivering school-based QPR (Question, Persuade, Refer) gatekeeper training, supported by an implementation intervention based on evidence-based implementation strategies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A two-phase case study with a feasibility hybrid evaluation design. The evaluation will include a multimethod approach including pre-, post- and follow-up survey measurements, field observations and semi-structured single and focus group interviews.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>A multimethod design will be used to validate the results. The use of methodological triangulation will help to reduce bias and deficiencies compared to using a single-method design.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70050","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143896939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Role Functioning in Clinical High Risk for Psychosis: An Open Trial of “InVEST” (Individualised Vocational and Educational Support and Training)","authors":"Michelle L. West,&nbsp;Julia Pfluger,&nbsp;Shadi Sharif,&nbsp;Claire Goods,&nbsp;Michelle Friedman-Yakoobian","doi":"10.1111/eip.70041","DOIUrl":"https://doi.org/10.1111/eip.70041","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>School and vocational (“role”) functioning is an important treatment target for young people exhibiting signs of clinical high risk for psychosis (CHR-P). However, there are currently no evidence-based approaches to help people at CHR-P with role functioning difficulties.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>This manuscript describes the development and pilot open trial evaluation of “InVEST” (Individualised Vocational and Educational Support and Training). InVEST is a coaching program designed to enhance role functioning in youth at CHR-P. InVEST is designed to be flexible, low-intensity, and easy-to-train, and it is carried out by bachelor's and undergraduate-level “coaches” who work with clients individually for 4 months. The intervention specifically targets three mechanisms believed to relate to role functioning in this clinical population: (1) organisation, (2) task initiation, and (3) distress resilience. This manuscript describes a small open trial and the iterative development of a manual based on participant feedback about this intervention in preparation for a randomised controlled trial.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All participants (<i>N</i> = 5) completed the baseline assessment, 16 weeks of coaching, and follow-up, with no dropouts. Participants reported high satisfaction with the program, and participant feedback was used to iterate and develop the InVEST manual. Additionally, most participants showed improvement in role functioning (4/5), organisation and planning (4/5), and task initiation (3/5) following InVEST participation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This small pilot study provides initial support for the feasibility and acceptability of InVEST and suggests that further study in comparison to a control condition is warranted.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143857042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstacles to Seeking Help: Perceived Barriers and Stigma Towards Mental Health Treatment in College Students at Elevated Risk for Psychosis","authors":"Benjamin Buck,&nbsp;Erica Whiting,&nbsp;Tess F. Filip,&nbsp;Madisen T. Russell,&nbsp;Sarah Akhras,&nbsp;Heather Busanet,&nbsp;Katherine N. Thakkar,&nbsp;Amanda McCleery,&nbsp;Kyle S. Minor","doi":"10.1111/eip.70034","DOIUrl":"https://doi.org/10.1111/eip.70034","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Although the college years are aligned with the typical age of onset of psychosis, few studies have examined identification and outreach programmes on college campuses. To inform future intervention targets and strategies, this study aimed to characterise treatment-seeking behaviours and attitudes, and perceived barriers to treatment in college students high in schizotypy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A sample of 200 college students (139 high schizotypy; 61 low schizotypy) completed questionnaires related to treatment-seeking behaviours, attitudes and barriers. Independent samples <i>t-</i>tests, Mann–Whitney <i>U</i> and Kruskal–Wallis tests were used to compare treatment-seeking behaviours, attitudes and barriers between schizotypy groups as well as among subgroups of those high in positive, negative and combined schizotypy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Students with elevated schizotypy not only reported higher rates of lifetime (56% vs. 36%) and recent (37% vs. 21%) treatment compared to those low in schizotypy, but also endorsed more negative attitudes towards help-seeking (<i>d</i> = 0.47). This latter finding was particularly true for those with primarily negative traits. The high schizotypy group also expressed greater concerns about embarrassment and fear of being treated differently related to treatment-seeking.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Although students with elevated schizotypy accessed treatment at higher rates, many remain untreated and report negative attitudes towards help-seeking. While not all students with elevated schizotypy require clinical intervention, these findings highlight the need for targeted interventions to address stigma and improve help-seeking behaviours among college students. This may be especially true for those experiencing distress or impairment associated with schizotypal traits.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143857043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mixed-Methods Evaluation of the Expanded Implementation of Supported Education Within Community Youth Mental Health Services","authors":"Oliver Ardill-Young,&nbsp;Scott Teasdale,&nbsp;Antonia Ottavio,&nbsp;Hannah Galley,&nbsp;Rose Singh,&nbsp;Ruby King,&nbsp;Philippa Levy,&nbsp;Alana Scully,&nbsp;Gina Chinnery,&nbsp;Jennifer Nicholas,&nbsp;Eóin Killackey,&nbsp;Jackie Curtis","doi":"10.1111/eip.70043","DOIUrl":"https://doi.org/10.1111/eip.70043","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Education is a key goal of young people experiencing mental ill-health and is crucial for many aspects of enjoyable, meaningful lives. However, the completion of education can be a challenge. This paper evaluated the expanded implementation of a targeted education support programme for young people with mental ill-health.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective chart audit of the 125 young people accessing a range of mental health services in a metropolitan region referred to the intervention between January 2022 and June 2023 was conducted. Education, demographic and administrative data were collected. The primary outcome was engagement in education (both secondary and higher), measured as both maintaining education and engaging in new educational opportunities. Fifteen clinicians were also surveyed on their perspectives on the intervention.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>One-hundred and twenty-two referrals were accepted, 93 young people engaged and 70 were supported to engage with education. Half of the young people who were not engaged in education prior to participating were successfully supported to re-engage. However, the intervention was less integrated between referring services than during a previous pilot phase. Clinicians viewed the intervention as contributing to the development of generalisable skills and enhancing efficacy of care, but viewed a lack of co-location at every site as a substantial barrier to integration.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In a large sample embedded in a real-world setting, the current paper demonstrates positive outcomes of supported education within youth mental healthcare. Further studies are needed to demonstrate efficacy with control groups and to explore the perspectives of young people and carers.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70043","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143857041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proof-of-Concept Pilot Study on the Integration of a Contingency Management Model to Address Substance Use Among Individuals Enrolled in Early Intervention Programs for Psychosis","authors":"Oladunni Oluwoye,&nbsp;Megan Puzia,&nbsp;Bryony Stokes,&nbsp;Elizabeth R. Fraser,&nbsp;Sheldon Stokes,&nbsp;Khairul Siddiqi,&nbsp;John M. Roll","doi":"10.1111/eip.70037","DOIUrl":"https://doi.org/10.1111/eip.70037","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Studies have reported high rates of alcohol and cannabis use and poor outcomes associated with substance use among individuals enrolled in coordinated specialty care (CSC) for first episode psychosis (FEP). Given these findings, substance use interventions within CSC would likely benefit individuals with FEP. This proof-of-concept study tested a standard and family-based contingency management (CM) model within CSC.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Fourteen participants were recruited from a CSC programme for FEP to participate in standard CM and family-based CM for substance use intervention developed and refined by an advisory board comprised of key stakeholders. The CM intervention consisted of personalising CM by allocating participants to receive standard CM or family-based CM. Participants submitted urinalysis samples to assess alcohol and cannabis use across a 2-week warm-up phase, followed by a 12-week active CM phase.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Approximately 60% of participants identified as an ethnoracial minority. At baseline, 78% of participants reported cannabis as the primary target substance and 64% opted into the family-based model. Eighty-four percent of urinalysis samples were submitted and 64% completed ≥ 8 weeks. Compared to baseline, substance use significantly decreased during the active CM phase (<i>p</i> &lt; 0.003).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This pilot study suggests that a flexible CM model to address alcohol and cannabis, with the option for family involvement, may be feasible in CSC settings and increase abstinence among young adults with FEP. A high percentage of urinalysis samples were submitted, although most participants completed less than 12 weeks of CM. While findings show promise, additional modifications and pilot studies are needed to further optimise CM for CSC prior to conducting a larger efficacy trial.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70037","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brief Report: Intact Cognitive Functions in Children and Adolescents of Parents With Mood Disorders","authors":"Mélanie Boisvert,&nbsp;Jules R. Dugré,&nbsp;Stéphane Potvin","doi":"10.1111/eip.70042","DOIUrl":"https://doi.org/10.1111/eip.70042","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>We aimed to identify if offspring of a parent with mood disorders presented cognitive deficits on 14 cognitive subtests while controlling for intellectual quotient, anxio-depressive symptoms, symptoms of attention deficit hyperactivity disorder (ADHD) or insomnia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using the Healthy Brain Network biobank, we identified 44 offspring of a parent with bipolar disorder (BD), 87 offspring of a parent with major depressive disorder (MDD) and 88 offspring of healthy parents. Analyses of variance (ANOVA) were performed to determine if groups differed on 14 subtests of the Wechsler Intelligence Scale for Children-5th Edition (WISC) and National Institutes of Health toolbox.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Across all subtests, groups did not significantly differ. Only a subtle effect was found for male participants in which high-risk participants exhibited lower scores on the mental rotation subtest compared to the control group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Overall, our results suggest intact cognition in young offspring of parents with a mood disorder.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143831455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refugee Migration Background and Healthcare Contacts Prior to First-Episode Psychosis in Young Adults in Denmark and Sweden: Are Patterns Consistent Across Countries?","authors":"Christopher Jamil de Montgomery,&nbsp;Amanda Falah Rasmussen,&nbsp;Jakob Bergström,&nbsp;Heidi Taipale,&nbsp;Aemal Akhtar,&nbsp;Allan Krasnik,&nbsp;Marie Nørredam,&nbsp;Ellenor Mittendorfer-Rutz,&nbsp;Alexis E. Cullen","doi":"10.1111/eip.70039","DOIUrl":"https://doi.org/10.1111/eip.70039","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The objective of this study was to examine group differences in healthcare contacts prior to a first diagnosis of non-affective psychotic disorders (NAPDs) comparing young refugees settled in Denmark and Sweden before turning 18 non-refugee migrants and native-born individuals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using nationwide register data, we identified all individuals aged 18–35 who received an NAPD diagnosis during 2006–2018. Healthcare contacts for other psychiatric disorders were categorised as inpatient, outpatient (grouped by discharge diagnosis) or dispensed antidepressant medication. Logistic regression was used in each country to compare contacts within 12 months prior to NAPD diagnosis, yielding odds ratios (OR) and corresponding 95% confidence intervals (CI), while standardised prevalence ratios (SPR), reported in percentages, were used to compare healthcare contact across countries.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We included 11,679 individuals in Denmark and 11,088 in Sweden. The likelihood of prior contact of any type was lower in both countries for both refugees [Denmark: OR = 0.75(CI: 0.63, 0.90); Sweden: OR = 0.61(CI: 0.55, 0.68)] and non-refugee migrants [Denmark: OR = 0.78(CI: 0.64, 0.95); Sweden: OR = 0.55(CI: 0.49, 0.62)] compared with majority peers. The largest differences were observed for dispensed antidepressants in both countries [Denmark: OR_refugees = 0.58(CI: 0.47, 0.71); Sweden: OR_refugees = 0.52(CI: 0.45, 0.61)]. Outpatient contacts in particular were more common in Sweden than in Denmark across all groups [SIR_refugees = 151% (CI: 125, 180)].</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Young refugees and non-refugee migrants in both Denmark and Sweden were less likely to have healthcare contact for other psychiatric disorders prior to NAPD onset than host populations. As healthcare contacts offer opportunities to identify treatment needs early, these groups may be vulnerable to delays in the pathway to treatment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}