Early Intervention in Psychiatry最新文献

{"title":"Anthropometric and Physiological Measures in Individuals With At-Risk Mental State (ARMS) Compared With Individuals With Schizophrenia: Findings From a Lower Middle-Income Country","authors":"M. O. Husain,&nbsp;M. Abid,&nbsp;A. B. Khoso,&nbsp;M. Riaz,&nbsp;F. Ahmed,&nbsp;S. Shakoor,&nbsp;S. Lane,&nbsp;N. Husain,&nbsp;G. Foussias,&nbsp;I. Qurashi,&nbsp;I. B. Chaudhry","doi":"10.1111/eip.70065","DOIUrl":"https://doi.org/10.1111/eip.70065","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Individuals with psychosis have reduced life expectancy and this is largely driven by cardiometabolic disease. Cardiometabolic risk increases with age and duration of psychotic illness. Anthropometric and physiologic abnormalities have been identified among individuals with at-risk mental state (ARMS) for psychosis. The prevalence of cardiometabolic disease is disproportionately higher in lower middle-income countries (LMIC); however, literature on cardiometabolic disease in individuals with psychosis spectrum disorders in LMIC is scarce.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>This is a cross-sectional secondary analysis of data from two large randomised controlled trials that recruited individuals with ARMS (<i>n</i> = 326) and schizophrenia (SCZ; <i>n</i> = 303) from inpatient and outpatient settings in Pakistan. All participants completed anthropometric and physiological assessments.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>There was a statistically significant difference in BMI between groups, 21.42 (SD = 4.11) in ARMS and 23.31 (SD = 5.41) in the SCZ group (<i>p</i> = 0.001). Although mean values were within the normal range, 17.8% (<i>n</i> = 58) of ARMS individuals and 33.1% (<i>n</i> = 100) SCZ individuals were overweight or obese. Waist circumference was 32.75 in (SD = 3.13) in the ARMS group and 32.16 in (SD = 5.18) in SCZ. Although waist circumference was higher in ARMS, this was not statistically or clinically significant. The pulse rate and blood pressure in both groups were within normal range.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>We found evidence of abnormal anthropometric and physiological parameters that would indicate that individuals with psychotic-spectrum disorders in Pakistan are at an elevated cardiometabolic risk.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 6","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70065","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144300247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sessions Abstracts","authors":"","doi":"10.1111/eip.70046","DOIUrl":"https://doi.org/10.1111/eip.70046","url":null,"abstract":"","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 S1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Keynote Lectures Abstracts","authors":"","doi":"10.1111/eip.70045","DOIUrl":"https://doi.org/10.1111/eip.70045","url":null,"abstract":"","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 S1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posters Abstracts","authors":"","doi":"10.1111/eip.70047","DOIUrl":"https://doi.org/10.1111/eip.70047","url":null,"abstract":"","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 S1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying Programme-Led and Focused Interventions for Early Intervention for Eating Disorders in Youth: A Rapid Review","authors":"Andrea LaMarre,&nbsp;Janessa Porter,&nbsp;Patricia Silva-Roy,&nbsp;Nicole Obeid","doi":"10.1111/eip.70053","DOIUrl":"https://doi.org/10.1111/eip.70053","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Early intervention (EI) for eating disorders (EDs) has been recognised as important for interrupting the onset of ED symptoms and improving outcomes. Despite growing evidence for EI models of service delivery in community-based settings, there is limited clarity on which specific interventions might best suit young people in these contexts. In this rapid review, we aimed to identify and explore the evidence for programme-led and focused interventions applicable to an EI service delivery model for youth with EDs in community-based settings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic search was conducted in MEDLINE, Web of Science, and PsycINFO databases, focusing on interventions that maximise the use of resources, namely guided self-help and group approaches, for individuals under age 30. Studies were screened for eligibility based on intervention brevity (12 sessions or fewer) and relevance to EI models.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Findings indicated that while many interventions reduced ED symptoms, few were explicitly designed for EI. Notably, interventions are skewed towards young adult populations, with fewer interventions addressing paediatric needs. Further, the strength of evidence for interventions varied, with many articles reporting on studies with small sample sizes or results illustrating non-superiority to comparison or control.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This review highlights the need for further research on programme-led and focused interventions tailored to EI, particularly for younger populations, to build an evidence base and improve early-stage ED treatment options in resource-limited community-based settings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 6","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening the Community for Individuals at Clinical High Risk (CHR) for Psychosis","authors":"Alexandre Andrade Loch,&nbsp;Anderson Ara,&nbsp;Feten Fekih-Romdhane,&nbsp;Leonardo Peroni de Jesus,&nbsp;Julio Cesar Andrade,&nbsp;Melina Mendonça,&nbsp;Maurício Henriques Serpa,&nbsp;Martinus Theodorus van de Bilt,&nbsp;Wagner Farid Gattaz","doi":"10.1111/eip.70056","DOIUrl":"https://doi.org/10.1111/eip.70056","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The aim of our study was to assess the performance of the Prodromal Questionnaire-16 (PQ-16) and the Perceptual and Cognitive Aberrations scale (PCA) to screen for clinical high risk for psychosis (CHR) in a sample of nonhelp-seeking subjects from São Paulo, Brazil.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Individuals aged 18–35 years were interviewed with the PQ-16 and the PCA. Those with a combined score &gt; 10 on the PQ-16 + PCA were called for assessment with the Structured Interview for Psychosis-Risk Syndromes (SIPS). Seventy-five individuals were deemed as CHR and 99 as healthy comparison; 44 randomly selected individuals (PQ-16 + PCA scores &lt; 10) joined as further controls. All participants had no DSM-5 diagnosis. Scores of the PCA, PQ-16 (total score and distress index), and their combinations were analysed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All the proposed scorings significantly distinguished between CHR and control subjects. Considering a 7% CHR prevalence in the population, PQ-16 score mathematically showed the best performance (AUC = 0.713), followed by the PQ-16 score + PCA (AUC = 0.701). PQ-16 distress had the worst performance (AUC = 0.642).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Data provides further evidence for the use of the PQ-16 score as an effective instrument to search for CHR states through active screening in the community. Future research should address its potential in helping CHR identification and thus reducing delays in care and minimising the risk of false positives.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 6","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70056","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proposed Standards for Implementing Stepped Care Models in Child and Youth Mental Health Service Systems: Results of a Pan-Canadian Delphi Study","authors":"S. Mughal,&nbsp;B. Young,&nbsp;A. Churchill,&nbsp;J. Rash,&nbsp;K. Tee,&nbsp;A. Salmon,&nbsp;J. L. Shah","doi":"10.1111/eip.70057","DOIUrl":"https://doi.org/10.1111/eip.70057","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Stepped care (SC) is being adopted in many countries as a framework for organising mental health care in diverse contexts. However, there is a lack of consistency in how SC has been defined and operationalised, limiting its effective application in practice. We describe the development of standards for implementing SC models in Canadian child and youth mental health (CYMH) contexts using a consensus-based approach. These standards are intended to support systems planners in creating cohesive CYMH systems across Canadian settings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study employed learning alliance and Delphi methodologies. A pan-Canadian multi-round Delphi process conducted in English and French was used to derive consensus on the inclusion and wording of individual clauses in the standard. Consensus with a threshold of 70% was set to determine the inclusion of individual clauses in the final standard.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Sixty-eight individuals participated in the Delphi study (with a 76.48% retention rate) representing lived experience, service delivery, policy, and research expertise. Over three rounds, 29 clause items were revised and reduced to a final list of 24 clause items comprising SC implementation standards. Participant feedback indicated a desire for reduced ambiguity, considerations of the limitations of patient autonomy, and the need to clarify roles and responsibilities in system-wide activities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>The results of this Delphi study represent the first multi-stakeholder, consensus-driven set of standards for implementing SC in CYMH settings across Canada. With these standards, we aspire to provide a blueprint for mental health systems advocacy and reform toward stronger, more coordinated CYMH systems.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 6","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70057","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144171874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Behavioural Patterns in Youth Predisposed to Bipolar Disorder and the Role of Interpersonal Trauma Using the Adolescent Brain Cognitive Development (ABCD) Dataset","authors":"Christina Ghaleb,&nbsp;Danielle Penney,&nbsp;Katie M. Lavigne,&nbsp;Delphine Raucher-Chéné","doi":"10.1111/eip.70058","DOIUrl":"https://doi.org/10.1111/eip.70058","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Bipolar disorder (BD) is a severe, persistent disorder that causes functional impairment. Besides heritability, environmental factors, such as traumatic experience, impact the development of BD. Little is known about the early developmental signs of this disorder; therefore, this study aims to look at the impact of interpersonal trauma on the early developmental signs of BD. Specifically, differences in psychopathological behaviours were investigated between (1) at-risk children and controls and (2) at-risk children who experienced an interpersonal traumatic event and those who did not.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using the Adolescent Brain Cognitive Development (ABCD) dataset, participants with a first-degree relative with BD were identified (<i>N</i>_at-risk = 625) and matched on sex and age to a control group (<i>N</i>_control = 625). The Kiddie Schedule for Affective Disorders and Schizophrenia (KSADS) was used to assess interpersonal trauma and psychopathological symptoms. The trauma (<i>N</i>_trauma = 198) and no-trauma sub-groups (<i>N</i>_no-trauma = 428) were built from the at-risk population. Group comparison was conducted on depressive, manic and anxiety symptoms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Compared to controls, at-risk children exhibited a significantly greater number of manic symptoms at baseline and 2-year follow-up, and anxiety symptoms at follow-up. No significant differences were found between the trauma and no-trauma groups at either baseline or follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>These results confirm the presence of early symptoms in at-risk children, in line with the staging model of BD. Extended longitudinal research is needed to further investigate the potential specific role of trauma on its early behavioural patterns.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 6","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70058","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144171875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of an Online Mental Health Website for the Early Intervention in Psychosis Services, Developed for the Early Youth Engagement (EYE-2) Trial: A Cross-Sectional Survey Study of Clinical Barriers and Facilitators to Normalisation","authors":"Elizabeth Robson,&nbsp;Kathryn Greenwood","doi":"10.1111/eip.70055","DOIUrl":"https://doi.org/10.1111/eip.70055","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Disengagement is a problem for early intervention in psychosis (EIP) services. Access to trusted information on a website might help to overcome some of the problems associated with disengagement. Clinician and organisational engagement are integral to the implementation and uptake of online resources.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims and Objectives</h3>\u0000 \u0000 <p>A theory-driven approach used the normalisation process theory (NPT) to investigate the implementation of an NHS psychoeducational website developed for the Early Youth Engagement Project (EYE-2). The aim was to establish barriers and facilitators to website use.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cross-sectional survey study was used; 36 EIP clinicians in Sussex were asked about their attitudes towards introducing the website and using it in appointments. Accessibility, usability and internet skills were also measured.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A key implementation barrier was lack of familiarity with the website and its content, which inhibited use. Poorer scores in the NPT ‘Collective Action’ construct relating to Skillset Workability and Relational Integration (staff confidence and ability) suggested that clinicians lacked confidence in their skills and ability to introduce the website in clinical sessions. Findings suggest that clinicians, might have lower operational skills compared to the general population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Embedding of nominated digital leads in teams as well as appropriate training is required to promote familiarity, confidence and enhance digital skills. Larger studies are required to establish the replicability of our findings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 6","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70055","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144171988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sun Exposure and Anorexia Nervosa: A Potential Environmental–Biological Interaction?","authors":"Andrea Phillipou","doi":"10.1111/eip.70054","DOIUrl":"https://doi.org/10.1111/eip.70054","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Despite first being described in 1888, anorexia nervosa continues to be the deadliest of all psychiatric illnesses. Although efforts have been made to elucidate the aetiological factors involved in the illness, little progress has been made in uncovering what contributes to the development and maintenance of anorexia nervosa. A particular shortcoming of the current literature has been the investigation of interactions between environmental and biological factors. One such interaction which has yet to receive attention in anorexia nervosa is that of sun exposure. Exposure to the sun—including levels of ultraviolet radiation (UVR) and vitamin D—in the pathogenesis of other mental illnesses has long been investigated (with lower levels of vitamin D reportedly involved in the pathogenesis of conditions such as schizophrenia, for example) but is yet to be explored in anorexia nervosa.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The current paper proposes a novel hypothesis for the potential contribution of reduced sun exposure in the aetiology of anorexia nervosa for future investigation, and possible mechanisms for how this relationship may operate.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 6","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70054","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}