Early Intervention in Psychiatry最新文献

{"title":"Enhancing Role Functioning in Clinical High Risk for Psychosis: An Open Trial of “InVEST” (Individualised Vocational and Educational Support and Training)","authors":"Michelle L. West,&nbsp;Julia Pfluger,&nbsp;Shadi Sharif,&nbsp;Claire Goods,&nbsp;Michelle Friedman-Yakoobian","doi":"10.1111/eip.70041","DOIUrl":"https://doi.org/10.1111/eip.70041","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>School and vocational (“role”) functioning is an important treatment target for young people exhibiting signs of clinical high risk for psychosis (CHR-P). However, there are currently no evidence-based approaches to help people at CHR-P with role functioning difficulties.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>This manuscript describes the development and pilot open trial evaluation of “InVEST” (Individualised Vocational and Educational Support and Training). InVEST is a coaching program designed to enhance role functioning in youth at CHR-P. InVEST is designed to be flexible, low-intensity, and easy-to-train, and it is carried out by bachelor's and undergraduate-level “coaches” who work with clients individually for 4 months. The intervention specifically targets three mechanisms believed to relate to role functioning in this clinical population: (1) organisation, (2) task initiation, and (3) distress resilience. This manuscript describes a small open trial and the iterative development of a manual based on participant feedback about this intervention in preparation for a randomised controlled trial.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All participants (<i>N</i> = 5) completed the baseline assessment, 16 weeks of coaching, and follow-up, with no dropouts. Participants reported high satisfaction with the program, and participant feedback was used to iterate and develop the InVEST manual. Additionally, most participants showed improvement in role functioning (4/5), organisation and planning (4/5), and task initiation (3/5) following InVEST participation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This small pilot study provides initial support for the feasibility and acceptability of InVEST and suggests that further study in comparison to a control condition is warranted.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143857042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstacles to Seeking Help: Perceived Barriers and Stigma Towards Mental Health Treatment in College Students at Elevated Risk for Psychosis","authors":"Benjamin Buck,&nbsp;Erica Whiting,&nbsp;Tess F. Filip,&nbsp;Madisen T. Russell,&nbsp;Sarah Akhras,&nbsp;Heather Busanet,&nbsp;Katherine N. Thakkar,&nbsp;Amanda McCleery,&nbsp;Kyle S. Minor","doi":"10.1111/eip.70034","DOIUrl":"https://doi.org/10.1111/eip.70034","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Although the college years are aligned with the typical age of onset of psychosis, few studies have examined identification and outreach programmes on college campuses. To inform future intervention targets and strategies, this study aimed to characterise treatment-seeking behaviours and attitudes, and perceived barriers to treatment in college students high in schizotypy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A sample of 200 college students (139 high schizotypy; 61 low schizotypy) completed questionnaires related to treatment-seeking behaviours, attitudes and barriers. Independent samples <i>t-</i>tests, Mann–Whitney <i>U</i> and Kruskal–Wallis tests were used to compare treatment-seeking behaviours, attitudes and barriers between schizotypy groups as well as among subgroups of those high in positive, negative and combined schizotypy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Students with elevated schizotypy not only reported higher rates of lifetime (56% vs. 36%) and recent (37% vs. 21%) treatment compared to those low in schizotypy, but also endorsed more negative attitudes towards help-seeking (<i>d</i> = 0.47). This latter finding was particularly true for those with primarily negative traits. The high schizotypy group also expressed greater concerns about embarrassment and fear of being treated differently related to treatment-seeking.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Although students with elevated schizotypy accessed treatment at higher rates, many remain untreated and report negative attitudes towards help-seeking. While not all students with elevated schizotypy require clinical intervention, these findings highlight the need for targeted interventions to address stigma and improve help-seeking behaviours among college students. This may be especially true for those experiencing distress or impairment associated with schizotypal traits.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143857043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mixed-Methods Evaluation of the Expanded Implementation of Supported Education Within Community Youth Mental Health Services","authors":"Oliver Ardill-Young,&nbsp;Scott Teasdale,&nbsp;Antonia Ottavio,&nbsp;Hannah Galley,&nbsp;Rose Singh,&nbsp;Ruby King,&nbsp;Philippa Levy,&nbsp;Alana Scully,&nbsp;Gina Chinnery,&nbsp;Jennifer Nicholas,&nbsp;Eóin Killackey,&nbsp;Jackie Curtis","doi":"10.1111/eip.70043","DOIUrl":"https://doi.org/10.1111/eip.70043","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Education is a key goal of young people experiencing mental ill-health and is crucial for many aspects of enjoyable, meaningful lives. However, the completion of education can be a challenge. This paper evaluated the expanded implementation of a targeted education support programme for young people with mental ill-health.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective chart audit of the 125 young people accessing a range of mental health services in a metropolitan region referred to the intervention between January 2022 and June 2023 was conducted. Education, demographic and administrative data were collected. The primary outcome was engagement in education (both secondary and higher), measured as both maintaining education and engaging in new educational opportunities. Fifteen clinicians were also surveyed on their perspectives on the intervention.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>One-hundred and twenty-two referrals were accepted, 93 young people engaged and 70 were supported to engage with education. Half of the young people who were not engaged in education prior to participating were successfully supported to re-engage. However, the intervention was less integrated between referring services than during a previous pilot phase. Clinicians viewed the intervention as contributing to the development of generalisable skills and enhancing efficacy of care, but viewed a lack of co-location at every site as a substantial barrier to integration.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In a large sample embedded in a real-world setting, the current paper demonstrates positive outcomes of supported education within youth mental healthcare. Further studies are needed to demonstrate efficacy with control groups and to explore the perspectives of young people and carers.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70043","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143857041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proof-of-Concept Pilot Study on the Integration of a Contingency Management Model to Address Substance Use Among Individuals Enrolled in Early Intervention Programs for Psychosis","authors":"Oladunni Oluwoye,&nbsp;Megan Puzia,&nbsp;Bryony Stokes,&nbsp;Elizabeth R. Fraser,&nbsp;Sheldon Stokes,&nbsp;Khairul Siddiqi,&nbsp;John M. Roll","doi":"10.1111/eip.70037","DOIUrl":"https://doi.org/10.1111/eip.70037","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Studies have reported high rates of alcohol and cannabis use and poor outcomes associated with substance use among individuals enrolled in coordinated specialty care (CSC) for first episode psychosis (FEP). Given these findings, substance use interventions within CSC would likely benefit individuals with FEP. This proof-of-concept study tested a standard and family-based contingency management (CM) model within CSC.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Fourteen participants were recruited from a CSC programme for FEP to participate in standard CM and family-based CM for substance use intervention developed and refined by an advisory board comprised of key stakeholders. The CM intervention consisted of personalising CM by allocating participants to receive standard CM or family-based CM. Participants submitted urinalysis samples to assess alcohol and cannabis use across a 2-week warm-up phase, followed by a 12-week active CM phase.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Approximately 60% of participants identified as an ethnoracial minority. At baseline, 78% of participants reported cannabis as the primary target substance and 64% opted into the family-based model. Eighty-four percent of urinalysis samples were submitted and 64% completed ≥ 8 weeks. Compared to baseline, substance use significantly decreased during the active CM phase (<i>p</i> &lt; 0.003).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This pilot study suggests that a flexible CM model to address alcohol and cannabis, with the option for family involvement, may be feasible in CSC settings and increase abstinence among young adults with FEP. A high percentage of urinalysis samples were submitted, although most participants completed less than 12 weeks of CM. While findings show promise, additional modifications and pilot studies are needed to further optimise CM for CSC prior to conducting a larger efficacy trial.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70037","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brief Report: Intact Cognitive Functions in Children and Adolescents of Parents With Mood Disorders","authors":"Mélanie Boisvert,&nbsp;Jules R. Dugré,&nbsp;Stéphane Potvin","doi":"10.1111/eip.70042","DOIUrl":"https://doi.org/10.1111/eip.70042","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>We aimed to identify if offspring of a parent with mood disorders presented cognitive deficits on 14 cognitive subtests while controlling for intellectual quotient, anxio-depressive symptoms, symptoms of attention deficit hyperactivity disorder (ADHD) or insomnia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using the Healthy Brain Network biobank, we identified 44 offspring of a parent with bipolar disorder (BD), 87 offspring of a parent with major depressive disorder (MDD) and 88 offspring of healthy parents. Analyses of variance (ANOVA) were performed to determine if groups differed on 14 subtests of the Wechsler Intelligence Scale for Children-5th Edition (WISC) and National Institutes of Health toolbox.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Across all subtests, groups did not significantly differ. Only a subtle effect was found for male participants in which high-risk participants exhibited lower scores on the mental rotation subtest compared to the control group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Overall, our results suggest intact cognition in young offspring of parents with a mood disorder.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143831455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refugee Migration Background and Healthcare Contacts Prior to First-Episode Psychosis in Young Adults in Denmark and Sweden: Are Patterns Consistent Across Countries?","authors":"Christopher Jamil de Montgomery,&nbsp;Amanda Falah Rasmussen,&nbsp;Jakob Bergström,&nbsp;Heidi Taipale,&nbsp;Aemal Akhtar,&nbsp;Allan Krasnik,&nbsp;Marie Nørredam,&nbsp;Ellenor Mittendorfer-Rutz,&nbsp;Alexis E. Cullen","doi":"10.1111/eip.70039","DOIUrl":"https://doi.org/10.1111/eip.70039","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The objective of this study was to examine group differences in healthcare contacts prior to a first diagnosis of non-affective psychotic disorders (NAPDs) comparing young refugees settled in Denmark and Sweden before turning 18 non-refugee migrants and native-born individuals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using nationwide register data, we identified all individuals aged 18–35 who received an NAPD diagnosis during 2006–2018. Healthcare contacts for other psychiatric disorders were categorised as inpatient, outpatient (grouped by discharge diagnosis) or dispensed antidepressant medication. Logistic regression was used in each country to compare contacts within 12 months prior to NAPD diagnosis, yielding odds ratios (OR) and corresponding 95% confidence intervals (CI), while standardised prevalence ratios (SPR), reported in percentages, were used to compare healthcare contact across countries.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We included 11,679 individuals in Denmark and 11,088 in Sweden. The likelihood of prior contact of any type was lower in both countries for both refugees [Denmark: OR = 0.75(CI: 0.63, 0.90); Sweden: OR = 0.61(CI: 0.55, 0.68)] and non-refugee migrants [Denmark: OR = 0.78(CI: 0.64, 0.95); Sweden: OR = 0.55(CI: 0.49, 0.62)] compared with majority peers. The largest differences were observed for dispensed antidepressants in both countries [Denmark: OR_refugees = 0.58(CI: 0.47, 0.71); Sweden: OR_refugees = 0.52(CI: 0.45, 0.61)]. Outpatient contacts in particular were more common in Sweden than in Denmark across all groups [SIR_refugees = 151% (CI: 125, 180)].</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Young refugees and non-refugee migrants in both Denmark and Sweden were less likely to have healthcare contact for other psychiatric disorders prior to NAPD onset than host populations. As healthcare contacts offer opportunities to identify treatment needs early, these groups may be vulnerable to delays in the pathway to treatment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review and Meta-Analysis on Effect of Metacognitive Training on Cognitive Biases in Patients With Schizophrenia: Implications for Psychiatric Nursing Care","authors":"Shen Jun,&nbsp;Du Miao,&nbsp;Jiang Ying","doi":"10.1111/eip.70026","DOIUrl":"https://doi.org/10.1111/eip.70026","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Schizophrenia presents significant challenges, with cognitive dysfunction being a hallmark feature affecting daily functioning.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>The study explores the impact of metacognitive training (MCT) on cognitive function in schizophrenia patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic review and meta-analysis encompassed 21 studies identified through databases and manual searches. Inclusion criteria focused on MCT interventions, controlled experimental designs and cognitive outcome measures. Data synthesis and meta-analysis followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The meta-analysis results revealed a significant effect of MCT on Cognitive Biases Questionnaire(CBQ)-catastrophizing (JTC) (No. studies = 3, SMD = −0.61, 95% CI: −0.98, −0.25; <i>I</i>² = 0.0%, <i>p</i> = 0.92) and CBQ-emotional reasoning(ER) (No. studies = 2, SMD = −0.50, 95% CI: −0.82, −0.18; <i>I</i>^<i>2</i> = 0.0%, <i>p</i> = 0.92), Positive and Negative Syndrome Scale (PANSS)-positive(P) (No. studies = 14, SMD = −0.52, 95% CI: −0.68, −0.35; <i>I</i>^<i>2</i> = 0.0%, <i>p</i> = 0.62), PANSS-negative(N) (No. studies = 8, SMD = −0.21, 95% CI: −0.42, −0.00; <i>I</i>^<i>2</i> = 0.0%, <i>p</i> = 0.94) and PANSS-total(T) (No. studies = 8, SMD = −0.42, 95% CI: −0.68, −0.16; <i>I</i>^<i>2</i> = 22.30%, <i>p</i> = 0.25) among schizophrenia patients. However, we found no significant impact of MCT treatment on CBQ-total(T), CBQ- intentionalizing (I), CBQ-catastrophizing(C), CBQ-dichotomous thinking(DT), Beck Cognitive Insight Scale(BCIS)-self-reflectiveness(SR), BCIS-self-certainty(SC), BCIS-composite index(CI) and PANSS-general(G) scores.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>MCT demonstrates a positive impact on cognitive biases and symptom severity in schizophrenia patients. These results advocate for innovative, personalised interventions to complement traditional approaches in schizophrenia management.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143822244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of Transdiagnostic Psychosocial Group Interventions and a Novel Peer Work Role in a Community Youth Mental Health Setting","authors":"Oliver Ardill-Young,&nbsp;Scott Teasdale,&nbsp;Paul Rich,&nbsp;Antonia Ottavio,&nbsp;Benjamin Lueck,&nbsp;Louise Treen,&nbsp;Michael Hodgins,&nbsp;Jackie Curtis","doi":"10.1111/eip.70038","DOIUrl":"https://doi.org/10.1111/eip.70038","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Group interventions can be an appropriate care option for young people with mental ill-health, yet there is a lack of research on their implementation within real-world settings. This paper aimed to explore the feasibility and acceptability of group interventions and a Group Coordinator peer work role in a community mental health service and the perspectives of young people, carers and staff on implementation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective chart audit of 121 referrals to group interventions from January 2022 to June 2023 was conducted. Education, demographic and administrative data were collected to explore feasibility and acceptability. Survey data from 44 young people who participated was also used to explore acceptability. Semi-structured interviews (8 young people, 7 carers and 11 staff) explored perspectives on implementation, mapping barriers and facilitators to domains of the Comprehensive Framework for Implementation Research.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Referrals made before the young person was involved in mental health treatment (i.e., at the stage of assessment) were less likely to result in engagement in a group, suggesting limited feasibility as a standalone care option. Young people reported overall positive experiences of group interventions, though attrition rates and qualitative interviews indicate they are perceived as less acceptable than individual options. The Group Coordinator role was viewed by staff as key to sustainability, with multiple benefits.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The current paper contributes to the scant literature on the implementation of group interventions with several practical implications for service planning. Further studies are needed to examine the implementation in other contexts, explore within-treatment variables and incorporate clinical outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Correlates of Suicide Attempts in Chinese Outpatients With First-Episode and Drug-Naïve Psychotic Major Depressive Disorder at Different Ages of Onset","authors":"ZhaoXuan Shang,&nbsp;ChunQing Fang,&nbsp;Xiao E Lang,&nbsp;XiangYang Zhang","doi":"10.1111/eip.70036","DOIUrl":"https://doi.org/10.1111/eip.70036","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Prior research has shown varying suicide attempt rates based on the age of onset in major depressive disorder (MDD) patients. However, there is a paucity of research on psychotic major depressive disorder (PMD) patients. This study aimed to assess the prevalence and correlates of suicide attempts in PMD patients stratified by age of onset.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Totally, 1718 first-episode drug-naïve MDD outpatients were recruited, divided into early-age onset (EAO) and middle-age onset (MAO) based on the first episode before age 45/after age 45. Clinical severity was assessed using the Hamilton Depression Rating Scale (HAMD), the Hamilton Anxiety Rating Scale (HAMA) and the Positive and Negative Syndrome Scale (PANSS) positive subscale. In addition, thyroid hormone and glucolipid metabolism indicators were measured.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In EAO PMD patients, HAMA scale score and thyroid-stimulating hormone (TSH) levels were associated with suicide attempts. The area under the receiver operating characteristic curve (AUROC) was 0.892. In MAO PMD patients, TSH and diastolic blood pressure were associated with suicide attempts. The AUROC was 0.862.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study demonstrates that the prevalence and correlates of suicide attempts vary among PMD patients with different ages of onset. Age of onset should be considered in the prevention and treatment of suicide attempts in patients with PMD.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143793308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Connection Learning Healthcare System Hub of the Early Psychosis Intervention Network: Program and Participant Characteristics","authors":"Monica E. Calkins,&nbsp;Megan Jumper,&nbsp;Arielle Ered,&nbsp;Fanghong Dong,&nbsp;Deepak K. Sarpal,&nbsp;Krista K. Baker,&nbsp;Donna J. Bencivengo,&nbsp;Russell L. Margolis,&nbsp;Robert W. Buchanan,&nbsp;Yasmine Boumaiz,&nbsp;Elizabeth Burris,&nbsp;Philip D. Campbell,&nbsp;K. N. Roy Chengappa,&nbsp;Catherine Conroy,&nbsp;Akinyi Cooke,&nbsp;Faith Dickerson,&nbsp;Nyasia Flowers,&nbsp;Mandy Fauble,&nbsp;Richard W. Goldberg,&nbsp;Alexander Harvin,&nbsp;Carolyn Howell,&nbsp;Christian Kelly,&nbsp;Julie Kreyenbuhl,&nbsp;Lan Li,&nbsp;Alicia Lucksted,&nbsp;Jill A. Marsteller,&nbsp;Alexander Moxam,&nbsp;Denise Namowicz,&nbsp;Swati Nayar,&nbsp;Jamie Oko,&nbsp;Jessie Riggs,&nbsp;Arunadevi Saravana,&nbsp;Rachel Scheinberg,&nbsp;William R. Smith,&nbsp;Richard States,&nbsp;Timur Suhail-Sindhu,&nbsp;Jerome Taylor,&nbsp;Crystal L. Vatza,&nbsp;Max Wolcott,&nbsp;Christian G. Kohler,&nbsp;Melanie E. Bennett","doi":"10.1111/eip.70031","DOIUrl":"https://doi.org/10.1111/eip.70031","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Connection Learning Healthcare System, one of the eight hubs of the National Institute of Mental Health funded Early Psychosis Intervention Network, supports uniform data collection, analysis, feedback and infrastructure development to promote a culture of continuous quality improvement across 25 Coordinated Specialty Care programs serving young people experiencing first episode psychosis and their families in Maryland and Pennsylvania. This first report describes the hub and its constituent programs, the approach for developing and implementing a hub-wide core assessment battery harmonised with the national battery, and preliminary program and participant characteristics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Our hub developed and implemented a computerised core assessment battery, administered every 6 months and developed an integrated system for managing and analysing data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Between 1 January 2021 and 27 November 2023, 1059 participants were newly admitted to a hub program. The entire cohort (<i>N</i> = 1381) included newly admitted participants and those already in a program as of 1 January 2021. A total of 1245 complete assessment batteries were collected across all time points from 797 participants, with an additional 1920 partially completed batteries collected from 1319 participants. Data are uploaded to the National Data Coordinating Center, where our hub is the third largest data contributor. Descriptive information on programs and participants is provided.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>As part of our learning healthcare system to improve clinical services and outcomes across two states, we have successfully implemented a standardised, computerised core assessment battery of essential characteristics and clinical outcomes. Successes, challenges and recommendations for data collection are provided. This paper will serve as a vital methodological resource for users of the unprecedented Early Psychosis Intervention Network national research database seeking to accelerate and improve early psychosis research.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}