日晒与神经性厌食症:潜在的环境-生物相互作用?

IF 2.1 4区 医学 Q3 PSYCHIATRY
Andrea Phillipou
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引用次数: 0

摘要

尽管在1888年首次被描述,神经性厌食症仍然是所有精神疾病中最致命的。尽管人们已经努力阐明了与该疾病有关的病因因素,但在揭示神经性厌食症的发展和维持的原因方面进展甚微。当前文献的一个特别缺点是对环境和生物因素之间相互作用的调查。其中一个在神经性厌食症中尚未引起注意的相互作用是阳光照射。长期以来,人们一直在研究暴露在阳光下——包括紫外线辐射(UVR)和维生素D水平——对其他精神疾病的发病机制的影响(据报道,维生素D水平较低与精神分裂症等疾病的发病机制有关),但对神经性厌食症的影响还有待探索。本文提出了一个新的假设,即减少阳光照射在神经性厌食症病因学中的潜在作用,并为未来的研究提供了可能的机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sun Exposure and Anorexia Nervosa: A Potential Environmental–Biological Interaction?

Objective

Despite first being described in 1888, anorexia nervosa continues to be the deadliest of all psychiatric illnesses. Although efforts have been made to elucidate the aetiological factors involved in the illness, little progress has been made in uncovering what contributes to the development and maintenance of anorexia nervosa. A particular shortcoming of the current literature has been the investigation of interactions between environmental and biological factors. One such interaction which has yet to receive attention in anorexia nervosa is that of sun exposure. Exposure to the sun—including levels of ultraviolet radiation (UVR) and vitamin D—in the pathogenesis of other mental illnesses has long been investigated (with lower levels of vitamin D reportedly involved in the pathogenesis of conditions such as schizophrenia, for example) but is yet to be explored in anorexia nervosa.

Conclusions

The current paper proposes a novel hypothesis for the potential contribution of reduced sun exposure in the aetiology of anorexia nervosa for future investigation, and possible mechanisms for how this relationship may operate.

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来源期刊
Early Intervention in Psychiatry
Early Intervention in Psychiatry 医学-精神病学
CiteScore
4.80
自引率
5.00%
发文量
112
审稿时长
6-12 weeks
期刊介绍: Early Intervention in Psychiatry publishes original research articles and reviews dealing with the early recognition, diagnosis and treatment across the full range of mental and substance use disorders, as well as the underlying epidemiological, biological, psychological and social mechanisms that influence the onset and early course of these disorders. The journal provides comprehensive coverage of early intervention for the full range of psychiatric disorders and mental health problems, including schizophrenia and other psychoses, mood and anxiety disorders, substance use disorders, eating disorders and personality disorders. Papers in any of the following fields are considered: diagnostic issues, psychopathology, clinical epidemiology, biological mechanisms, treatments and other forms of intervention, clinical trials, health services and economic research and mental health policy. Special features are also published, including hypotheses, controversies and snapshots of innovative service models.
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