Sexual Activity and Risky Sexual Behaviour Amongst Canadian Youth With and at Risk for Bipolar Disorder

IF 2.2 4区 医学 Q3 PSYCHIATRY
Jessica Barton, Mikaela K. Dimick, Vanessa Timmins, Eric A. Youngstrom, Benjamin I. Goldstein
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Abstract

Aim

Despite substantial evidence in adults, data on sexual behaviour in youth with bipolar disorder (BD) are limited. We therefore examined this topic in youth with BD.

Method

The study included 625 youth (n = 246 BD, n = 233 high risk for BD [BD-risk] and 146 healthy controls [HC]), ages 13–20 years. Semi-structured interviews evaluated diagnoses and treatment, as well as sexual activity, risky sexual behaviour (RSB) and reasons for RSB. Analyses compared lifetime sexual activity and RSB across the three groups and evaluated correlates of sexual activity and RSB within BD and BD-risk.

Results

Lifetime sexual activity and RSB were significantly higher amongst both BD and BD-risk youth versus HC. In univariate analyses, several overlapping clinical and suicide risk factors were associated with lifetime sexual activity amongst both BD and BD-risk youth. In multivariate analysis amongst BD youth, comorbid substance use disorder (SUD), post-traumatic stress disorder, and family history of anxiety were associated with lifetime sexual activity. In BD-risk youth, older age, lifetime depression severity, comorbid SUD and interpersonal chaos were associated with lifetime sexual activity. Affective lability and family history of suicide attempt were associated with RSB.

Conclusions

Lifetime sexual activity was two-fold greater, and RSB was over fifteen-fold greater, amongst BD and BD-risk youth versus HCs. Understanding which demographic and clinical factors are associated with lifetime sexual activity amongst BD and BD-risk youth may enable us to identify youth more likely to engage in RSB and help us develop treatments and preventative strategies to avoid RSB accordingly.

加拿大青年双相情感障碍患者和高危人群的性活动和危险性行为
尽管在成人中有大量证据,但关于青少年双相情感障碍(BD)性行为的数据是有限的。因此,我们在患有双相障碍的青少年中研究了这一主题。方法研究纳入了625名青少年(n = 246名BD患者,n = 233名BD高危人群[BD-risk]和146名健康对照者[HC]),年龄在13-20岁之间。半结构化访谈评估了诊断和治疗,以及性活动、危险性行为(RSB)和RSB的原因。分析比较了三组的终生性活动和RSB,并评估了性活动和RSB在BD和BD风险中的相关性。结果双相障碍和双相障碍风险青年的终生性活动和RSB明显高于HC。在单变量分析中,几个重叠的临床和自杀风险因素与双相障碍和双相障碍风险青年的终生性活动有关。在双相障碍青年的多变量分析中,共病性物质使用障碍(SUD)、创伤后应激障碍和焦虑家族史与终生性活动相关。在bd风险青年中,年龄、终生抑郁严重程度、共病性SUD和人际关系混乱与终生性行为有关。情感不稳定和自杀企图家族史与RSB相关。结论:与hcc相比,BD和BD风险青年的终生性活动多2倍,RSB多15倍。了解哪些人口统计学和临床因素与双相障碍和双相障碍风险青年的终生性活动有关,可以帮助我们确定更容易发生RSB的青年,并帮助我们制定相应的治疗和预防策略,以避免RSB。
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来源期刊
Early Intervention in Psychiatry
Early Intervention in Psychiatry 医学-精神病学
CiteScore
4.80
自引率
5.00%
发文量
112
审稿时长
6-12 weeks
期刊介绍: Early Intervention in Psychiatry publishes original research articles and reviews dealing with the early recognition, diagnosis and treatment across the full range of mental and substance use disorders, as well as the underlying epidemiological, biological, psychological and social mechanisms that influence the onset and early course of these disorders. The journal provides comprehensive coverage of early intervention for the full range of psychiatric disorders and mental health problems, including schizophrenia and other psychoses, mood and anxiety disorders, substance use disorders, eating disorders and personality disorders. Papers in any of the following fields are considered: diagnostic issues, psychopathology, clinical epidemiology, biological mechanisms, treatments and other forms of intervention, clinical trials, health services and economic research and mental health policy. Special features are also published, including hypotheses, controversies and snapshots of innovative service models.
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