Current Microbiology最新文献

{"title":"Curtobacterium uvaldense sp. nov., Falsirhodobacter allii sp. nov., Pseudomonas texasensis sp. nov., Three Novel Species Isolated from Onions in Texas, USA.","authors":"Manzeal Khanal, Bed Prakash Bhatta, Lakhvir Kaur, Subas Malla","doi":"10.1007/s00284-026-05144-1","DOIUrl":"10.1007/s00284-026-05144-1","url":null,"abstract":"<p><p>Bacterial strains 20TX0008^T and 20TX0035^T were isolated from the symptomatic onion foliage in 2020, and a bacterial strain 21TX0197^T was isolated from the symptomatic onion bulb in 2021. Pathogenicity assays confirmed the two strains isolated from foliage to be non-pathogenic, while the strain 21TX0197^T was found to be pathogenic. Phylogenetic analysis using the 16 S rRNA gene revealed the closest resemblance of 20TX0008^T, 20TX0035^T, and 21TX0197^T to the genera Curtobacterium, Falsirhodobacter, and Pseudomonas, respectively. For the respective genus, strains 20TX0008^T showed the greatest 16 S rRNA sequence similarity with Curtobacterium caesinilyticum GDMCC 1.2667^T (99.7%), 20TX0035^T with Falsirhodobacter deserti W402^T (99.1%), and 21TX0197^T with Pseudomonas uvaldensis 20TX0172^T (99.4%). In the phylogenetic trees based on whole genome sequences, all three strains formed a distinct, well-supported branch that separated them from their closely related species within the same genus. The genomic similarity, based on average nucleotide identity (ANI) and digital DNA-DNA hybridization (dDDH), revealed that the novel strains had values below the species delineation thresholds (ANI < 95% and dDDH < 70%), confirming the novelty of all these strains. Based on genomic and phenotypic characteristics, we propose three novel species, Curtobacterium uvaldense sp. nov. (type strain 20TX0008^T =LMG 33207^T =NCIMB 15480^T), Falsirhodobacter allii sp. nov. (type strain 20TX0035^T =LMG 33208^T =NCIMB 15477^T), and Pseudomonas texasensis sp. nov. (type strain 21TX0197^T =LMG 33210^T =NCIMB 15479^T).</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"83 11","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13558446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148918733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a Novel Compound Probiotic Paste Containing Canine-Derived Vitamin B12-Producing Limosilactobacillus Reuteri.","authors":"Xiaoyan Zheng, Xinyi Dong, Sadat Abdulla Aziz, Sichao Mao, Yongwang Liu, Xinyi Xu, Xingxiang Chen","doi":"10.1007/s00284-026-05139-y","DOIUrl":"10.1007/s00284-026-05139-y","url":null,"abstract":"<p><p>Chronic diarrhea in pets features high incidence, often causing vitamin B12 deficiency. Probiotics, which can alleviate or even treat chronic diarrhea by improving intestinal microbial balance, have shown promise. Previously, our laboratory isolated a strain of Limosilactobacillus reuteri (CLAB) with vitamin B12-producing capability from canine feces. However, it had suboptimal palatability and insufficient efficacy against chronic diarrhea and vitamin B12 deficiency. In this study, the CLAB was combined with Enterococcus faecalis and Saccharomyces cerevisiae to formulate a compound probiotic paste. The properties of the paste were comprehensively evaluated via a series of experiments including sensory evaluation, pH testing, microbial colony counting, palatability tests, disease activity index scoring, histopathological analysis, biochemical indicator analysis, and RNA quantification. The results demonstrated that the paste exhibited good stability, safety, and favorable palatability in both dogs and cats. Meanwhile, it significantly alleviated chronic diarrhea and vitamin B12 deficiency in mice. Specifically, the high-dose compound probiotic paste decreased myeloperoxidase and malondialdehyde levels in diarrheic mice from approximately 15.9 and 2.5 nmol/mgprot to about 4.2 and 1.7 nmol/mgprot; increased the total antioxidant capacity content and superoxide dismutase activity from approximately 0.5 nmol/mgprot and 1.0 U/mgprot to about 0.6 nmol/mgprot and 1.6 U/mgprot; and downregulated the relative mRNA levels of interleukin-6, interleukin-1β and tumor necrosis factor-α from approximately 2.1, 2.1 and 2.7 to about 1.2, 1.1 and 1.3, respectively. In conclusion, this study supports the potential use of the compound probiotic paste for preventing and treating chronic diarrhea and improving vitamin B12 deficiency in pets.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"83 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: HIV-1 and Vaccine: Analysis of gp41 Target Sequences.","authors":"Salvatore Dimonte, Rossana Scutari, Romina Salpini, Stefano Aquaro, Valentina Svicher, Michele Pellegrino","doi":"10.1007/s00284-026-05045-3","DOIUrl":"10.1007/s00284-026-05045-3","url":null,"abstract":"","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"83 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudaquabacterium prasiolae sp. nov., Isolated from the Freshwater Green Alga Prasiola japonica, and Rubrivivax soli sp. nov., Isolated from Soil, with Reclassification of Aquabacterium humicola as Pseudaquabacterium humicola comb. nov.","authors":"Jae Kyeong Lee, Seo Hui Choi, Seon Hoo Jung, Yeong Eun Kwon, Jeong Min Kim, Che Ok Jeon","doi":"10.1007/s00284-026-05151-2","DOIUrl":"10.1007/s00284-026-05151-2","url":null,"abstract":"<p><p>Two Gram-stain-negative, catalase- and oxidase-positive, strictly aerobic, non-flagellated rod-shaped bacteria, designated OR-4^T and RP6-9^T, were isolated from the freshwater green alga Prasiola japonica and soil in Republic of Korea, respectively. Strain OR-4^T exhibited gliding motility, whereas strain RP6-9^T lacked gliding motility. Strain OR-4^T grew at 10-30 °C, pH 6.0-9.0, and 0-1.5% (w/v) NaCl, while strain RP6-9^T grew at 20-35 °C, pH 6.0-9.0, and 0-1.0% (w/v) NaCl. Both strains contained ubiquinone-8 as the sole respiratory quinone and phosphatidylethanolamine, phosphatidylglycerol, and diphosphatidylglycerol as major polar lipids; strain OR-4^T additionally possessed an unidentified phospholipid and an unidentified polar lipid. The predominant fatty acids of OR-4^T were C_12:0, C_16:0, summed feature 3 (C_16:1ω6c and/or C_16:1ω7c), and summed feature 8 (C_18:1ω7c and/or C_18:1ω6c), whereas RP6-9^T contained C_12:0, C_16:0, and summed feature 3 as major components. The genomic DNA G + C content of both strains was 71.0 mol%. Whole-genome-based phylogenomic analyses placed OR-4^T and RP6-9^T within the genera Pseudaquabacterium and Rubrivivax, respectively, forming distinct lineages. Comparative analyses of average nucleotide identity, digital DNA-DNA hybridization, and average amino acid identity further supported their assignment to these genera while confirming their separation from previously described species. Based on combined phenotypic, chemotaxonomic, and genomic evidence, strains OR-4^T and RP6-9^T represent novel species, for which the names Pseudaquabacterium prasiolae sp. nov. (type strain OR-4^T =KACC 22752^T =NBRC 116024^T) and Rubrivivax soli sp. nov. (type strain RP6-9^T =KACC 24055^T =DSM 119932^T) are proposed. Phylogenomic analyses also support the reclassification of Aquabacterium humicola as Pseudaquabacterium humicola comb. nov. (type strain RJY3^T =KCTC 92105^T =NBRC 115831^T).</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"83 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial Properties and Ecotoxicity of Azo Oxime Ether - Emerging First-in-class Fungicide for Crop Protection.","authors":"Yulia O Bukarinova, Polina A Kuryntseva, Svetlana Yu Selivanovskaya, Alexander S Budnikov, Vera A Vil', Igor B Krylov, Alexander O Terent'ev","doi":"10.1007/s00284-026-05148-x","DOIUrl":"10.1007/s00284-026-05148-x","url":null,"abstract":"<p><p>Currently, the resistance of phytopathogenic fungi to widely used fungicides is increasing. The intensification of agricultural production due to population growth precludes the abandonment of chemical plant protection products. Therefore, the search for new compounds with fungicidal activity represents an urgent research direction. In this study, the biological activity (fungicidal and antimicrobial properties) and ecotoxicological profile of a leading compound from novel fungicide class, azo oxime ethers, were investigated. The test compound (TC) inhibited the growth of several phytopathogenic fungi, including Alternaria alternata, Geotrichum candidum, Fusarium graminearum, while demonstrating minimal effects on non-target microorganisms, such as the bacteria Azospirillum sp., Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Pseudomonas fluorescens, and the yeasts Pichia sp., Saccharomyces cerevisiae, and Wickerhamomyces anomalus. The toxicity toward aquatic organisms (Ceriodaphnia affinis, Chlorella vulgaris, Paramecium caudatum) did not exceed that of tebuconazole, which was used as a reference in the form of commercial product \"Kolosal\". Phytotoxicity toward Raphanus sativus and Triticum aestivum was observed only at the maximum tested concentration of 0.01%. In addition, ecotoxicological properties were studied for ethoxylated isodecyl alcohol, widely used emulsifier and wetting agent in crop-protection products. These results suggest that the studied compound is a promising active ingredient for the development of plant protection agents.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"83 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caerin 1.1/1.9 Inhibits Growth and Biofilm Formation of Carbapenem-Resistant Klebsiella pneumoniae and Induces Coordinated Transcriptomic Stress Responses.","authors":"Zhijun Lin, Quanlan Fu, Junjie Li, Jinyi Wu, Hongyin Wu, Yongxin Liang, Yuandong Luo, Wei Yang, Hejie Li, Tianfang Wang, Guoying Ni, Xiaosong Liu","doi":"10.1007/s00284-026-05135-2","DOIUrl":"10.1007/s00284-026-05135-2","url":null,"abstract":"<p><p>Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a major cause of healthcare-associated infections and a World Health Organization critical-priority pathogen due to extensive antimicrobial resistance and limited treatment options. Host-defense peptides represent promising alternatives to conventional antibiotics because of their broad-spectrum activity and low propensity for resistance development. Here, we evaluated the antibacterial activity of a fixed 1:1 combination of the frog-derived peptides caerin 1.1 and caerin 1.9 (F1/F3) against a reference K. pneumoniae strain and four clinical CRKP isolates. Individually, F1 and F3 exhibited MICs of 12 µM against the reference strain, whereas the F1/F3 combination reduced the MIC to 5 µM and showed an additive antibacterial interaction. F1/F3 retained activity against clinical CRKP isolates with strain-dependent susceptibility and inhibited biofilm formation and reduced pre-established biofilm biomass in a concentration-dependent manner. Scanning electron microscopy revealed pronounced morphological and surface alterations following peptide treatment. Transcriptomic analysis demonstrated broad bacterial responses to F1/F3 exposure, including downregulation of genes associated with ribosomal function, protein synthesis, metabolism, and oxidative phosphorylation, together with activation of stress-response pathways and differential expression of predicted small regulatory RNAs. SNP analysis revealed no evidence of increased mutation burden following peptide exposure. These findings demonstrate the antibacterial potential of F1/F3 against CRKP and provide insights into bacterial responses associated with caerin peptide treatment.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"83 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly Efficient Photodynamic Inactivation of Multidrug-resistant Pseudomonas aeruginosa, Staphylococcus aureus and Acinetobacter baumannii Strains by Toluidine Blue-graphene Oxide Quantum Dot/Ag Nanoparticle Conjugate.","authors":"Marieh Salahshour, Esmaeil Darabpour, Michael R Hamblin","doi":"10.1007/s00284-026-05146-z","DOIUrl":"10.1007/s00284-026-05146-z","url":null,"abstract":"<p><p>Photodynamic inactivation (APDI) is a novel and promising approach for the treatment of bacterial infections. Nanoparticle-based photosensitizer delivery systems can improve the efficacy of APDI. This study aimed to determine whether graphene quantum dot/silver nanoparticles (GQD/AgNPs) hybrid as a nanocarrier system could enhance the efficacy of toluidine blue (TBO)-mediated PDI against multidrug-resistant (MDR) Pseudomonas aeruginosa, Staphylococcus aureus and Acinetobacter baumannii strains. At first, the negatively-charged GQD/AgNP hybrids were synthesized using the pyrolysis method combined with hydrothermal processing. Then, the cationic TBO was immobilized to anionic GQD/AgNP hybrids via electrostatic attraction. The tested bacterial strains growing as planktonic cells were treated with TBO alone and TBO-conjugated GQD/AgNPs nanohybrid and subsequently exposed to laser light (650 nm). Meanwhile, the impacts of PDI using TBO-conjugated GQD/AgNP hybrids on planktonic bacterial cells were visualized using field emission scanning electron microscopy (FESEM). Also, the inhibitory effect of TBO-GQD/AgNPs-mediated PDI on biofilm formation was assessed. PDI using TBO-GQD/AgNPs conjugate revealed significant antibacterial activity compared to TBO-mediated PDI, so that the planktonic cells of P. aeruginosa/A. baumannii and S. aureus were almost completely eradicated by TBO-GQD/AgNPs-mediated PDI at Sub-lethal concentrations of 10 and 5 µM of TBO, respectively. FESEM analysis confirmed the potent ability of TBO-GQD/AgNPs-mediated PDI to kill P. aeruginosa, S. aureus and A. baumannii cells. Also, the results indicated that PDI mediated by TBO-GQDs/AgNP (at sub-lethal dose) completely inhibited biofilm formation by all three tested bacteria. In summary, PDI mediated by TBO-GQD/AgNPs offer a new modality for fast and efficient elimination of MDR P. aeruginosa, S. aureus and A. baumannii strains.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"83 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Marine Vibrio Biocatalysts as Unique Green Transformation (GX) Tools at the Time to Sustainable Development Goals (SDGs).","authors":"Tomoo Sawabe, Mami Tanaka, Chiori Yoshifuji, Hannah Kaufmann, Fabiano Thompson, Chunqi Jiang, Sayaka Mino","doi":"10.1007/s00284-026-05039-1","DOIUrl":"10.1007/s00284-026-05039-1","url":null,"abstract":"","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"83 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leaf Curl Disease Resistance Landscaping in Homozygous Ty-Gene Donor Tomato Genotypes Using a Robust Disease Scoring System and Indexing of Begomoviruses Under Natural Epiphytotic Conditions.","authors":"Firoz Mondal, Shipra Saxena, Zakir Hussain, Mehulee Sarkar, Bikash Mandal, Kajal Kumar Biswas, Satish Kumar Yadav, Anirban Roy","doi":"10.1007/s00284-026-05132-5","DOIUrl":"10.1007/s00284-026-05132-5","url":null,"abstract":"<p><p>Whitefly-transmitted begomoviruses cause tomato leaf curl disease (ToLCD). In India, at least 15 begomoviruses are known to cause ToLCD, posing a major challenge to resistance breeding. Although several Ty resistance loci have been introgressed from wild tomato relatives, variable resistance responses are frequently observed, likely due to mixed infections and the absence of a standardized disease scoring system. Moreover, limited knowledge of the infecting begomoviruses in resistant genotypes has hindered the effective use of donor lines in breeding programs. This study evaluated 17 homozygous Ty-gene donor tomato genotypes under natural epiphytotic conditions and identified the associated begomoviruses. To quantify disease severity, a robust disease scoring system was developed using coefficient of infection (CI) by integrating symptom parameters- leaf curling, leaf smalling, stunting, and fruiting, with population-level disease incidence. Field evaluations for two years revealed that genotypes carrying both Ty-2 and Ty-3 loci showed higher resistance, though variability existed among them. Genotypes with Ty-3 alone or Ty-5 + Ty-6 combinations also displayed substantial tolerance, and five genotypes were identified as highly resistant. Molecular indexing revealed frequent mixed infections and identified multiple begomoviruses, including a newly characterized species, tomato leaf curl Ty Pusa virus, alongside tomato leaf curl New Delhi virus, tomato leaf curl Palampur virus, tomato leaf curl Gujarat virus, and tomato leaf curl Joydebpur virus. These findings highlight a shift in begomovirus predominance and possible recombination-driven emergence of new variants. This study provides an integrated framework for evaluating ToLCD resistance and emphasizes the need for continuous reassessment of resistance sources to ensure durable tomato cultivar development.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"83 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148873452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptive Laboratory Evolution of the Hydrocarbonoclastic Marine Strain Rhodococcus ruber MSA14 to High Pyrene Concentrations.","authors":"Gabriela Calcáneo-Hernández, Salvador Embarcadero-Jiménez, Hortencia Silva-Jiménez, Dimitris Georgellis","doi":"10.1007/s00284-026-05142-3","DOIUrl":"10.1007/s00284-026-05142-3","url":null,"abstract":"<p><p>Rhodococcus ruber MSA14, isolated from oil-polluted coastal sediments in Baja California, Mexico, has previously been shown to degrade pyrene, highlighting its potential for polycyclic aromatic hydrocarbons (PAH) bioremediation. In the present study, MSA14 was subjected to adaptive laboratory evolution using progressively increasing concentrations of pyrene as the sole carbon and energy source, resulting in the isolation of a high-pyrene-adapted strain, R. ruber AD0911. Compared with the parental strain, AD0911 displayed improved growth and pyrene tolerance, modified colony morphology, enhanced biofilm biomass, altered biosurfactant production patterns, and increased oxidative stress tolerance. Whole-genome sequencing and breseq-based variant calling identified 75 mutations in AD0911 relative to MSA14, affecting membrane-associated proteins, transcriptional regulators, cell signaling, and stress-response components. These adaptive mechanisms identified in AD0911 provide new insight into the evolution of bacterial tolerance under high hydrocarbon stress and suggest that adaptation to extreme pyrene exposure was driven primarily by physiological optimization rather than changes in PAH catabolic enzymes.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"83 10","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13526041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148857016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}