Current Microbiology最新文献

{"title":"Current Approaches and Implications in Discovery of Novel Bioactive Products from Microbial Sources.","authors":"Ankesh Pandey, Juveriya Israr, Janmejay Pandey, Sankalp Misra","doi":"10.1007/s00284-025-04237-7","DOIUrl":"10.1007/s00284-025-04237-7","url":null,"abstract":"<p><p>Bioactive Natural Products (BNPs) are in high demand due to their disease-preventive capabilities and resistance to pathogens. However, our understanding of BNP-producing microbes is limited, because many microbial populations remain uncultivated. Various approaches have been employed to explore the potential of these hidden microbes for new bioactive therapeutic compounds. Nevertheless, the possibility of discovering BNPs from microbial communities is largely cryptic due to their unculturable nature and the absence of triggers to activate the dormant Biosynthetic Gene Clusters (BGCs). Metagenome sequencing, followed by mining and characterization, is an effective approach for discovering new therapeutic BNPs. The inactive state of BGCs can be activated through the combinatorial interaction of different microbial communities within a common niche, overcoming programmable co-evolutionary stress and producing new BNPs. The present review discusses and explores the potential of hidden, uncultivated microbes for discovering novel Bioactive Natural Products (BNPs). Moreover, it provides insights into optimizing microbial production systems and fostering sustainable drug discovery and development practices by integrating multidisciplinary strategies. This review also emphasizes the critical role of microbial sources in the ongoing search for new bioactive products that can meet the demands of modern healthcare and environmental sustainability.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"258"},"PeriodicalIF":2.3,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unlocking Rhizosphere Dynamics: Exploring Mechanisms of Plant-Microbe Interactions for Enhanced Tea (Camellia sinensis (L.) O. Kuntze) Productivity.","authors":"Pranami Bharadwaj, Chingakham Juliya Devi, Debajit Thakur","doi":"10.1007/s00284-025-04235-9","DOIUrl":"10.1007/s00284-025-04235-9","url":null,"abstract":"<p><p>The rhizosphere, the interface between plant roots and soil, refers to the contact zone where plants and soil microbes engage in beneficial and parasitic interactions. The significant interactions and their importance form a dynamic interface between the roots of plants and the soil. Beneficial ones, especially plant growth-promoting bacteria (PGPB) and arbuscular mycorrhizal fungi (AMF), improve plant development and enhance stress resistance due to microbial secretions, exudates from roots, and edaphic factors. All these are very important in cultivating tea (Camellia sinensis (L.) O Kuntze) plants, boosting growth, yield, and leaf content of amino acids, proteins, caffeine, and polyphenols. Yet, the molecular mechanisms of such interactions necessitate high-end technologies like genome editing and proteomics to fine-tune rhizosphere dynamics for greater plant health and productivity. The root exudates, rich in nutrients, serve as a source of food for the soil microbes while facilitating communication and colonisation by beneficial organisms, such as AMF and bacteria, thus significantly impacting the performance of a tea plant. High nitrogen fertilisers are readily applied in tea farming, although environmental risks include soil acidification and increased emissions of nitrous oxide (N₂O), a potent greenhouse gas. Understanding and manipulating plant root-soil microbe interactions are critical for developing sustainable farming systems that enhance productivity without causing environmental damage. This review describes the mechanisms by which beneficial microbes function in the rhizosphere, strategies for modifying root exudates to improve tea production, and the tea microbiome's underexplored potential in contributing towards sustainability. This review thus emerges as one that presents knowledge gaps and possible future directions in tea microbiome science predicated on the amelioration of tea farming by enhancing productivity and ensuring environmental sustainability.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"257"},"PeriodicalIF":2.3,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cytomegalovirus Infection Affects the Differentiation and Determines the Functionality of a Human Progenitor Neural Cell Line.","authors":"H M González-Sánchez, E I Rubio Hernández, A S Silva-Ramírez, A Miranda-López, A E Monsiváis-Urenda, M Comas-García, D E Noyola, V M Rodríguez, C G Castillo","doi":"10.1007/s00284-025-04231-z","DOIUrl":"10.1007/s00284-025-04231-z","url":null,"abstract":"<p><p>Cytomegalovirus (CMV) is a leading cause of congenital infections and one of the most common causes of neurodevelopmental disabilities worldwide. Despite the critical consequences of CMV infection in the brain, little is known about the mechanisms of neuropathogenesis responsible for malformations and dysfunction in the central nervous system. Some reports point out the infection of neural precursor cells (NPCs) as a key element in this process; these cells show the greatest susceptibility to CMV in the developing brain. In order to further characterize how CMV perturbs NPCs properties, we investigated the effect of human CMV strain AD169 in the neural stem cell cycle, viability, phenotype, and function of hNS-1 cells (immortalized cell line of human fetal brain). Notably, both infected and non-infected cells undergo apoptosis, with CMV infection not inducing a higher rate of apoptosis compared to non-infected cells. Upon infection and induction of differentiation in hNS-1 cells, the transcriptional expression of the NMDA receptor and the astrocyte marker GFAP is significantly reduced. Immunofluorescence assays corroborate the inhibition of astrocyte differentiation by CMV infection, while differentiation to neurons remains unaffected. Furthermore, our study demonstrates that CMV-infected hNS-1 cells exhibit impaired responses to multiple agonists after differentiation, including purinergic and GABAergic neurotransmission. These observations shed light on the previously understudied aspect of human CMV's influence on NPCs' function, providing valuable insights into the intricate interplay between CMV and neural development.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"256"},"PeriodicalIF":2.3,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudomonas aeruginosa Quorum Signals; Associations with Virulence, and Impact of Therapeutic Gamma Radiation Doses.","authors":"Radwa N Morgan, Reham R El-Behery","doi":"10.1007/s00284-025-04210-4","DOIUrl":"10.1007/s00284-025-04210-4","url":null,"abstract":"<p><p>Quorum sensing (QS) signals are the fundamental regulators of P. aeruginosa cellular machinery. From this perspective, this study aimed to analyze a pathogenic Pseudomonas aeruginosa isolate quorum signals profile prior and following exposure to therapeutic gamma radiation doses, and associate them with their virulence. Analysis of quorum signals was conducted utilizing GC-Mass spectroscopy and CFM-ID 4.0 mass spectra prediction webserver. The correlation between these signals and P. aeruginosa virulence was investigated through in vitro and computational methods. The isolates pyocyanin, biosurfactant, and biofilm productions were quantified before and after gamma irradiation and the STRING-DB were used to scrutinize the QS synthesizing proteins interactions. Further, the Cytoscape software statistically analyzed the QS proteins-proteins interaction networks. The study reported the recovery of acyl-homoserine lactones (C2, C4, C6, and C12-HSLs) and fatty acid signals (DSFs) from the P. aeruginosa isolate ethyl acetate extract and proposed the potential isolation of longer-chain HSLs (> C12-HSLs). New functional associations were identified for QS synthesizing proteins, which involve spermidine, fatty acids, and siderophores biosynthesis. The irradiated P. aeruginosa extracts GC-MS chromatograms exhibited notable changes in the retention times of QS signals and their mass spectra with the retrieval of different forms of fatty acids esters. Additionally, irradiated P. aeruginosa demonstrated a modest increase in the production of both biofilms and biosurfactants. This finding indicated that changes in quorum signals profile post irradiation boosted P. aeruginosa virulence mechanisms, which may potentially lead to an exacerbation of infection pathogenesis following the application of therapeutic gamma radiation doses.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"255"},"PeriodicalIF":2.3,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and Virulence Gene Profiling of Arcobacter spp. from Seafood and Its Environment.","authors":"Fathima Salam, Kalli Vasanthi, Veeranki Sai Krishna, Manjusha Lekshmi, Sanath Kumar, Binaya Bhusan Nayak","doi":"10.1007/s00284-025-04220-2","DOIUrl":"10.1007/s00284-025-04220-2","url":null,"abstract":"<p><p>Arcobacter spp. are emerging microaerophilic human pathogens associated with food-borne outbreaks worldwide. The present study reports the incidence and virulence gene characterization of Arcobacter spp. from seafood. Using the selective isolation method, a total of 112 arcobacters were isolated from 43 samples out of the 123 samples screened, comprising 71 finfish, 29 crustaceans, 13 molluscan and 10 water samples. The overall incidence of Arcobacter spp. was 34.96%, with highest in water (50%), followed by mollusca (46.15%), finfish (33.8%), and cephalopods (27.59%). The isolates were confirmed by polymerase chain reaction using Arcobacter genus and species-specific primers. Among 112 Arcobacter isolates, 62 were identified as A. butzleri, 17 as A. skirrowii, 14 as A. cryaerophilus and 19 as other arcobacters. Selected isolates (n = 52) comprising 19 A. butzleri, 17 A. skirrowii, and 14 A. cryaerophilus were screened for the presence of seven putative virulence genes, among which, ciaB was predominantly present in 94% of the isolates, whereas hecB was found absent in all test isolates. More than one virulence gene was present in 94% of the isolates screened. These findings suggest the pathogenic potential of seafood isolates of arcobacters, which further necessitates the need for detailed investigations on their molecular virulence mechanisms.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"254"},"PeriodicalIF":2.3,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization and Genomic Analysis of a Lytic Vibriophage vB_VneS_S3 of Infecting Vibrio neocaledonicus.","authors":"Qiyue Yang, Shujuan Sun, Hongbing Shao, Yue Su, Ni Wang, Xin Chen, Meiaoxue Han, Jinhao Shen, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Andrew McMinn, Min Wang, Yantao Liang","doi":"10.1007/s00284-025-04239-5","DOIUrl":"10.1007/s00284-025-04239-5","url":null,"abstract":"<p><p>Vibrio is a prevalent marine bacteria, distinguished by their remarkable genomic flexibility. Although Vibrio neocaledonicus is well known for effectively inhibiting carbon steel corrosion, nothing is known about its viruses. This study identified a new lytic vibriophage vB_VneS_S3. Transmission electron microscopy analysis showed that vB_VneS_S3 is a siphoviral morphology with an icosahedral head and long non-contractile tail. It is a linear, dsDNA with a length of 76,083 bp and a G + C content of 48.97%, encodes 101 ORFs. Average nucleotide sequence identification and phylogenetic analysis demonstrated that phage vB_VneS_S3 is a new species within the genus of Mardecavirus. Biogeographic analysis revealed that vB_VneS_S3 was exclusively identified in the Arctic, where it exhibited low abundance. In conclusion, our results provided basic information about the interaction between V. neocaledonicus and viruses, increased our knowledge of phylogenetic diversity, genomic characteristics, and distribution of the novel phage.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"251"},"PeriodicalIF":2.3,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fungal Infections Resulting From Prolonged Use of Personal Protective Equipment.","authors":"Elif Aydin, Duygu Percin Renders, Selve Arslan Utku, Derya Berikten","doi":"10.1007/s00284-025-04227-9","DOIUrl":"10.1007/s00284-025-04227-9","url":null,"abstract":"<p><p>This study is the first to investigate fungal infections resulting from prolonged use of personal protective equipment (PPE) among healthcare workers at Kütahya Health Sciences University Evliya Çelebi Training and Research Hospital, during the COVID-19 pandemic. The research aimed to isolate, molecularly type, and assess the antifungal susceptibility of superficial fungal infection agents associated with PPE use. Additionally, the relationship between these fungi and PPE use was evaluated through a questionnaire. Samples were collected from 100 healthcare workers experiencing skin issues. Among them, all N95/FFP2 mask users, 44.3% of glove users, 36.1% of surgical mask users, and 22.9% of hair cap users reported skin reactions, with acne (n = 34) being the most common. Identified fungal isolates included Trametes hirsuta, Penicillium chrysogenum, Aspergillus fumigatus, Rhodotorula sp., Candida sp., Pichia fermentans, and the dermatophyte Microsporum ferrugineum. Antifungal susceptibility tests revealed 47.6% resistance to fluconazole and 76.2% resistance to voriconazole (n = 16). This study provides the first institutional data on PPE-associated fungal infections and antifungal resistance in healthcare settings. These findings highlight the dermatological risks of prolonged PPE use. To mitigate these effects, healthcare institutions should prioritize high-quality materials, establish optimal usage guidelines, and provide continuous training on self-protection.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"253"},"PeriodicalIF":2.3,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomic Characterization of Serratia fonticola (EBS19) as a Biocontrol Agent against Botrytis cinerea.","authors":"Efe Berk Bozkurt, Ömür Baysal, Anna Marzec-Grządziel, Ragıp Soner Silme, Ahmet Can, İlayda Nur Belen, Ümran Çapar, Ahmet Korkut","doi":"10.1007/s00284-025-04224-y","DOIUrl":"10.1007/s00284-025-04224-y","url":null,"abstract":"<p><p>Botrytis cinerea (Bc), a plant pathogenic fungus, is the causative agent of gray mold disease, which rapidly develops resistance to fungicides in cultivation areas. This study explores the biocontrol potential of various bacterial isolates collected from the rhizosphere of tomato plants (Solanum lycopersicum). Bacterial isolates were purified and neutralized through phenol vaporization for 2 days. Colonies that inhibited pathogen spore growth were confirmed via antibiosis effect using in vitro bioassays. Bacterial colonies demonstrated up to 84% inhibition of pathogen growth at 7-day post-inoculation (dpi) with a one-layer agar diffusion test and up to 70% inhibition with a double-layer agar diffusion test, compared to control plates. Both bacterial suspension and filtrate significantly suppressed pathogen mycelium growth at 11 and 14 dpi. The isolate used in further studies was identified as Serratia fonticola (EBS19) through whole-genome sequencing. Annotated genome data revealed the presence of genes encoding enzymes crucial for pathogen inhibition. Carbon preference analyses identified specific carbon sources unique to the bacterial strain. These findings are advantageous for developing effective biopreparations that ensure bacterial strain stability in practical applications. In addition, the primary focus was on the interaction between the pathogen's major stress regulator protein (BAG1) and the bacterial glycoside hydrolase. Protein-protein docking analyses elucidated strong interaction between BAG1 and bacterial glycoside hydrolase. In conclusion, this study provides a knowledge for further research using recombinant DNA and gene cloning techniques on the bacterium's mapped genome.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"252"},"PeriodicalIF":2.3,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proposal of Paenibacillus kandeliae sp. nov, Isolataed from Leaf of Kandelia candel.","authors":"Cheng-Shao Zan, Xiao Ma, Xiao-Hui Chen, Ming-Sheng Chen, Li Tuo","doi":"10.1007/s00284-025-04225-x","DOIUrl":"10.1007/s00284-025-04225-x","url":null,"abstract":"<p><p>A novel bacterial strain, designated JQZ6Y-1^T, was isolated from the leaf of Kandelia candel at Maowei sea Mangrove Nature Reserve, Guangxi Zhuang Autonomous Region, China. The 16S rRNA gene sequence phylogenetic and phylogenomic analysis revealed that strain JQZ6Y-1^T formed a stable clade with Paenibacillus wenxiniae DSM 100576^T and Paenibacillus hunanensis CGMCC 1.8907^T within the genus Paenibacillus. The 16S rRNA gene sequence similarities of strain JQZ6Y-1^T with the related species P. wenxiniae DSM 100576^T and P. hunanensis CGMCC 1.8907^T were 98.3% and 98.2%, respectively. The average nucleotide identity values of strain JQZ6Y-1^T with the related species P. wenxiniae DSM 100576^T and P. hunanensis CGMCC 1.8907^T were 77.5% and 80.4%, respectively. The digital DNA-DNA hybridization values of strain JQZ6Y-1^T with the related species P. wenxiniae DSM 100576^T and P. hunanensis CGMCC 1.8907^T were 22.9% and 23.0%, respectively. These values clearly indicated that strain JQZ6Y-1^T represented a novel species. The diagnostic diamino acid in the cell-wall peptidoglycan of strain JQZ6Y-1^T was meso-diaminopimelic acid, and MK-7 was the predominant menaquinone. The polar lipids comprised diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine, two unidentified aminophospholipids, two unidentified phospholipids, and one unidentified lipid. The major fatty acids were anteiso-C_15:0 and C_16:0. Cells of strain JQZ6Y-1^T were Gram positive and rod shaped. Optimum growth occurred at pH 7.0, 30 ℃, and with 1-2% (w/v) NaCl. Based on phylogenomic and phylogenetic analyses coupled with phenotypic and chemotaxonomic characterizations, strain JQZ6Y-1^T could be classified as a novel species of the genus Paenibacillus, for which the name Paenibacillus kandeliae sp. nov. is proposed. The type strain is JQZ6Y-1^T (=CGMCC 1.18974^T = JCM 34547^T).</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"250"},"PeriodicalIF":2.3,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Overview of the Current Approaches in Drug-Resistant Bacterial Removal Within Wastewaters: Can We Move Towards Nanomagnet-Porphyrin Hybrids for Antimicrobial Photodynamic Inactivation (aPDI).","authors":"Mbalenhle Kabelo Nhlabathi-Chidi, Neo Mokgadi Mametja, Thabo Thokozani Innocent Nkambule, Usisipho Feleni, Tracy Masebe, Muthumuni Managa","doi":"10.1007/s00284-025-04222-0","DOIUrl":"10.1007/s00284-025-04222-0","url":null,"abstract":"<p><p>The rise in the occurrence of drug-resistant bacteria within wastewater treatment plants (WWTPs) and their dissemination into the ecosystem from the same WWTPs has created a prevalent crisis affecting the integrity of human life and water sources worldwide. Antimicrobial Photodynamic Inactivation (aPDI) can be explored in an effort to address this crisis and preserve natures integrity as it can incorporate environmentally sustainable and cost-effective disinfection strategies within wastewater treatment plants. aPDI is a technique introduced as a strategic approach to inactivate harmful Drug-Resistant Bacteria (DRB) that are ineffectively removed with current wastewater treatment strategies. The incorporation of Nanomagnet-Porphyrin Hybrid (NMPH) based aPDI illustrates notable microbial inactivation and innovatively introduces prospects of achieving affordable and ecologically beneficial disinfection within wastewaters since they can be recycled and reused. Furthermore the added advantage of NMPHs based aPDI lies in the generation of a high quantum yield of cytotoxic ¹O₂ due to a strong visible absorption ascribed to π-π* electronic transitions within the porphyrins. These properties are largely ascribed to the high coefficient of light absorption in a broad wavelength range allowing them to generate reactive oxygen species through a spin-forbidden intersystem crossing mechanism allowing them to demonstrate express disinfection of harmful pathogens. This review addresses the high inactivation profiles of NMPH based aPDI, its low operating costs and reusability as the potential of establishing NMPH based aPDI in nanotechnology wastewater remediation and microbial disinfection applications. The authors believe that this systematic review can stimulate new researchers and assist in the future development of this important field of research, especially when it comes to the aquatic environment and natural water resources and given the adequate attention this method can aid globally but more so within emerging economies to ensure potable water is delivered to all people.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"249"},"PeriodicalIF":2.3,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}