Current Microbiology最新文献

{"title":"Co-variation of Host Gene Expression and Gut Microbiome in Intestine-Specific Spp1 Conditional Knockout Mice.","authors":"Na Li, Guangqi Gao, Tao Zhang, Chunyan Zhao, Yue Zhao, Yong Zhang, Zhihong Sun","doi":"10.1007/s00284-025-04246-6","DOIUrl":"10.1007/s00284-025-04246-6","url":null,"abstract":"<p><p>Osteopontin, which is a highly phosphorylated and glycosylated acidic secreted protein encoded by the secreted phosphoprotein 1 (Spp1) gene, plays a crucial role in immune regulation, inflammatory responses, and cell adhesion. However, its impact on intestinal gene expression and gut microbiota remains underexplored. In this study, we developed an Spp1 conditional knockout mouse model to investigate alterations in the intestinal transcriptome and microbiome, with particular emphasis on changes in gene expression and predicted metabolic pathways. Our findings demonstrated that Spp1 gene conditional knockout significantly modified the expression of genes involved in immune regulation and lipid metabolism. Moreover, metagenomic analysis revealed marked shifts in gut microbial diversity and predicted the metabolic pathways associated with digestion, absorption, and lipid metabolism. These results suggest that Spp1 is instrumental in maintaining gut microbial equilibrium and in regulating host lipid metabolism and immune responses. This study offers new insights into the role of Spp1 in host-microbiota interactions and the potential foundations for developing related therapeutic strategies.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"282"},"PeriodicalIF":2.3,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and Characterisation of Gracilimonas aurantiaca sp. nov., A Novel Bacterium Isolated from Tidal-Flat Sediment.","authors":"Jaincy N Jayan, Sathiyaraj Srinivasan, Sang-Seob Lee","doi":"10.1007/s00284-025-04257-3","DOIUrl":"10.1007/s00284-025-04257-3","url":null,"abstract":"<p><p>A novel bacterium MJW-20^T, was isolated from deep tidal-flat sediment in Gochang, Republic of Korea. The isolate is a bright-orange, Gram-stain-negative, aerobic, non-motile, slow-growing long-rods. The strain MJW-20^T is oxidase, and catalase-positive. The growth is observed at 25-40 °C (optimum, 30 °C) and pH 5-9 (optimum, pH 7.0) in the presence of 0-9% (w/v) NaCl (optimum, 2.0% NaCl). The NCBI 16S ribosomal RNA sequences showed that the strain MJW-20^T is closely affliated with Balneola vulgaris 13IX/A01/164^T (94.6%), Gracilimonas halophila WDS2C40^T (94.5%), Gracilimonas amylolytica LA399^T (94.0%), Gracilimonas rosea CL-KR2^T (93.8%) and Balneola alkaliphila CM41_14b^T (93.3%) from the family Balneolaceae. The major respiratory quinone was MK-7. The major polar lipids identified were diphosphatidylglycerol (DPG), phosphatidylglycerol (PG), phospholipid (PL) and phosphatidylinositolmannosides (PIMs) for strain MJW-20^T.The major cellular fatty acids of type strain MJW-20^T were C_15:0 iso (32.9%), C_16:1 ω7c/C_16:1 ω6c (11.9%), and C_16:0 10-methyl/C_17:1 iso ω9c (15.9%). The genome length of the type strain MJW-20^T is 3.1 Mbp (DNA G + C content, 44%). It has 2,785 coding genes and 38 tRNAs. The analysis promotes that the average amino acid identity values, average nucleotide identity values, and biochemical, phylogenetic, and physiological characteristics support the genotypic and phenotypic differentiation of strain MJW-20^T from other species of the genus Gracilimonas. Thereupon, the strain MJW-20^T is considered to represent a novel species of the genus Gracilimonas, for which the name Gracilimonas aurantiaca sp. nov. is proposed. The type strain is MJW-20^T (= KCTC 102297^T = JCM 37229^T).</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"277"},"PeriodicalIF":2.3,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asymbiotic Nitrogen Fixation in the Phyllosphere of Urban Green Spaces.","authors":"Jian-Feng Li, Le-Yang Yang, Zhao Zhang, Xin-Rong Huang, Hu Li, Shun Li, Xiao-Ru Yang","doi":"10.1007/s00284-025-04250-w","DOIUrl":"10.1007/s00284-025-04250-w","url":null,"abstract":"<p><p>Biological nitrogen fixation (BNF) is an important source of nitrogen in ecosystems. Compared to symbiotic nitrogen-fixing microorganisms, free-living diazotrophic bacteria have a broader distribution and greater diversity, demonstrating greater potential for application. Leaf surfaces constitute one of the largest microbial reservoirs on Earth, harboring a variety of free-living diazotrophic bacteria, contributing significantly to plant N acquisition and growth. The distribution patterns, abundance, diversity, and the environmental variables affecting the asymbiotic nitrogen fixation (ANF) rates of free-living diazotrophic bacteria of non-leguminous plants in urban green spaces were investigated using high-throughput sequencing of nifH gene amplicons and the acetylene reduction method. Both green space type and plant species significantly impact ANF rates and nifH gene abundance in the phyllosphere, with green space type having a more pronounced effect. Leaf metal elements iron (Fe), molybdenum (Mo), and the free-living diazotrophic bacteria of the genus Skermanella collectively influence the ANF rates in the phyllosphere of urban green spaces. Linear regression analysis revealed that metal elements Fe, Mo, and potassium (K) in the leaves were significantly positive correlated with the diversity of the free-living diazotrophic bacteria and the abundance of the N-fixing gene nifH. The alpha diversity and symbiotic network structure of the free-living diazotrophic bacterial community in the phyllosphere indicated a significant negative correlation between human disturbance and environmental perturbation and the biodiversity and network complexity of these bacteria. This study provides a crucial foundation for understanding the nitrogen-fixing functions of microbes in urban ecosystems and their contributions to the nitrogen cycle.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"276"},"PeriodicalIF":2.3,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seed Endophytic Bacteria from Manilkara zapota L. and Their Influence as Rice Seed Priming Agents.","authors":"Titir Guha, Suparna Mandal Biswas","doi":"10.1007/s00284-025-04253-7","DOIUrl":"10.1007/s00284-025-04253-7","url":null,"abstract":"<p><p>In recent years, seed endophytes have gained significant attention due to their impact on the ecology, health, and productivity of host plants. Extensive research is being conducted to explore novel endophytic bacteria for sustainable crop improvement. Manilkara zapota L. P. Royen (Sapotaceae) is a highly stress-tolerant tree widely cultivated in tropical countries, yet its associated endophytes remain unexplored. In this study, nine bacterial isolates were obtained from M. zapota seeds, of which three (LA2, LA4, and NS1) were selected based on their IAA production capability which ranged from 2.3, 6.34, and 16.1 µg mL^-1, respectively. Identification through 16S rRNA sequencing confirmed LA2 as Pseudomonas rhodesiae, LA4 as Bacillus cereus, and NS1 as Enterobacter cloacae. All isolates exhibited nitrogen-fixing ability, while NS1 uniquely solubilized potassium and phosphorus with KSI and PSI value as 2.9 and 2.3, respectively. Further, the efficacy of the bacterial isolates in promoting rice seedling growth was evaluated, and novel bioformulation was prepared from the consortia of LA2 + LA4, LA2 + NS1, LA4 + NS1, and LA2 + LA4 + NS1. All the isolates and bioformulations were tested as biopriming agents. Rice seedling growth experiments revealed a significant increase in germination percentage, root length, and shoot length following biopriming with individual isolates and consortia. Among treatments, the LA2 + LA4 combination exhibited the highest growth promotion, with a root length increase of 2.1-fold and shoot length increase of 2.3-fold as compared to control. Thus, our results highlighted that bioprospecting microbes from M. zapota seeds can help in nutrient management and seedling establishment.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"275"},"PeriodicalIF":2.3,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Yield of Prodigiosin by Serratia marcescens Ka3 Using Additive Huangshui, a Byproduct of Chinese Liquor (Baijiu).","authors":"Chuan Wang, Zhongxing Gao, Rui Han, Yaomei Tian, Hongjun Fan, Yuliang Zhang","doi":"10.1007/s00284-025-04242-w","DOIUrl":"10.1007/s00284-025-04242-w","url":null,"abstract":"<p><p>Huangshui, a characteristic byproduct of Chinese liquor production, was first used as an additive to promote the production of prodigiosin with Serratia marcescens Ka3 in a 5 L bioreactor. Based on the prodigiosin levels in the peptone glycerol medium, the yield of prodigiosin reached 48,341 mg/L after adding 1% Huangshui following 60 h of fermentation, which is currently a high yield in bioreactors. The purity of the prodigiosin extracted from the fermentation broth and purified using a microporous filter membrane was 97%. Purified prodigiosin showed significant inhibitory effects on human lung carcinoma A549 cells and human colon adenocarcinoma HT29 cells. It also inhibited the human gastric adenocarcinoma SGC7901 cells, albeit not significantly. The IC₅₀ of prodigiosin against A549, HT29, and SGC7901 cells were 0.39 μg/mL, 0.45 μg/mL, and 1.30 μg/mL, respectively. The results of the present study showed that prodigiosin production using Huangshui had the advantages of high yield, simple purification, high purity, and anticancer activity. Therefore, Huangshui is a potential additive that promotes the production of microbial secondary metabolites such as prodigiosin.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"272"},"PeriodicalIF":2.3,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and Biological Characteristics of Rare Pathogen Comamonas kerstersii in the First Case of Gallbladder Puncture Fluid.","authors":"Juntong Zhou, Xin Cheng, Liyan Ma, Zhenqi Li, Shuilong Guo","doi":"10.1007/s00284-025-04264-4","DOIUrl":"10.1007/s00284-025-04264-4","url":null,"abstract":"<p><p>Comamonas kerstersii is an environmental microorganism, and clinical infections caused by this species are rare. In this study, the strain CXZJT123 was isolated from gallbladder puncture fluid and identified using a comprehensive approach including morphological observation, mass spectrometry, biochemical identification, 16S rRNA sequencing, and whole-genome sequencing. The morphological characteristics of CXZJT123 were consistent with the Comamonas. Mass spectrometry initially identified the strain as Comamonas aquatica, while biochemical assays demonstrated key features aligning with the Comamonas genus. Phylogenetic analysis of 16S rRNA sequences placed CXZJT123 in the same clade as C. kerstersii (NR 025530.1). Whole-genome sequencing followed by gene annotation using the Non-Redundant Protein Database (NR) revealed the highest gene homology with C. kerstersii. Further genomic analysis using the Virulence Factors of Pathogenic Bacteria (VFDB) and the Comprehensive Antibiotic Research Database (CARD) identified the presence of virulence genes, including those encoding flagella (flg series) and biofilm formation (pil series), as well as antibiotic resistance genes such as macB, arlR, and evgS. This study presents the first reported isolation of C. kerstersii isolated from gallbladder puncture fluid. The findings contribute valuable insights into the identification, genomic characteristics, and potential pathogenicity of C. kerstersii, providing a useful reference for the diagnosis and management of related infections.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"273"},"PeriodicalIF":2.3,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional and Amino Acid Composition of Scenedesmus sp. Cultivated Under Various Light Intensities.","authors":"Seyit Uguz, Arda Sozcu, Ercan Simsek, Erkan Yaslioglu","doi":"10.1007/s00284-025-04248-4","DOIUrl":"10.1007/s00284-025-04248-4","url":null,"abstract":"<p><p>Microalgae like Scenedesmus sp. are promising alternatives for sustainable food and animal feed due to their high protein content and adaptability to different light intensities. Optimal light enhances growth and nutrient accumulation, while excessive light can reduce productivity. This study investigates the effects of different light intensities (100-300 µmol m⁻² s⁻¹) on the growth performance and nutritional composition of Scenedesmus sp., aiming to improve microalgae production efficiency and contribute to commercial standards for sustainable protein sources. Results show that dry biomass concentration (0.975 g L^-1) and cell count (2.96) peaked at a light intensity of 200 μmol m^-2 s^-1 (P < 0.0001), while dry biomass decreased at 300 μmol m⁻² s⁻¹. Scenedesmus sp. grown at 200 and 300 µmol m^-2 s^-1 had higher carbohydrate contents (50.1% and 54%, P < 0.001), while the highest lipid content (42.3%) was observed at 100 µmol m^-2 s^-1. The highest crude protein was recorded at 200 µmol m^-2 s^-1 (15.6%, P < 0.0001). Regarding amino acid composition, leucine was the most abundant essential amino acid (1.20 mg/100 mg dry weight), while glutamic acid was the most abundant non-essential amino acid (1.73 mg/100 mg). For color characteristics, biomass produced at 300 µmol m^-2 s^-1 exhibited a darker color, with the lowest L* value (21.66), and a more yellowish hue compared to 200 µmol m^-2 s^-1. These findings highlight the importance of optimizing light conditions to enhance Scenedesmus sp. productivity for sustainable animal feed applications. This study indicates that the productivity of Scenedesmus sp. could be enhanced for biomass and protein production by maintaining an optimal light regime. By maximizing biomass yield and nutrient composition, this study supports the development of microalgae-based protein sources that can serve as a viable alternative to conventional feed ingredients, contributing to more sustainable and efficient feed production systems.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"274"},"PeriodicalIF":2.3,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nano-encapsulated Melissa officinalis Essential Oil and Its Antibacterial Effects Against Multi Drug Resistant E. coli and K. pneumonia.","authors":"Fateme Lotfi, Mehran Nemattalab, Zahra Hesari","doi":"10.1007/s00284-025-04157-6","DOIUrl":"10.1007/s00284-025-04157-6","url":null,"abstract":"<p><p>Urinary tract infections (UTIs) are common bacterial infections in children, frequently caused by E. coli and K. pneumoniae, whose biofilm-forming ability makes them resistant to antibiotics. In order to investigate an alternate drug delivery system to combat the microbial resistance, M. officinalis essential oil with its inherent antimicrobial properties was loaded in solid lipid nanoparticles (SLN) to properly enhance its antibacterial effects. Physico-chemical evaluations along with antibacterial assessment were conducted. Dynamic light scattering (DLS) results revealed that SLNs had an average size of 138.8 ± 34.3 nm and a zeta potential of -32.3 mV. Transmission electron microscopy (TEM) images confirmed their cuboid structure and smooth surface. The encapsulation efficiency of MO-SLN was 83 ± 2.1% and cumulative oil release from MO-SLN was 86.34 ± 0.1 in 72 h. The antibacterial activity of MO-SLN and MO were reported with MIC and MBC values of 545-570 µgmL^-1, 1240-1260 µgmL^-1 and 365-395 µgmL^-1, 925-955 µgmL^-1 for MDR E. coli and K. pneumoniae, respectively. Consequently, MO-SLN significantly reduced the MIC compared to pure MO, indicating that SLN as a nanocarrier can significantly increase the antibacterial effects of Melissa officinalis essential oil.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"271"},"PeriodicalIF":2.3,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Phase-Specific Dynamics in Gene Expression of Salmonella Typhimurium During Acanthamoeba castellanii Infection.","authors":"A S Balkin, S V Cherkasov, Y V Gogolev, A O Plotnikov","doi":"10.1007/s00284-025-04256-4","DOIUrl":"10.1007/s00284-025-04256-4","url":null,"abstract":"<p><p>Being facultative intracellular pathogens, the bacterium often is found in the environment. In natural habitats, Salmonella are able to survive and multiply inside free-living protists that support preservation and distribution of the pathogen, its virulence, and resistance to antimicrobial agents. At the same time, the expression profile of Salmonella genes in the eukaryotic cells has been shown not to be stable, but changes dramatically according to the sequential stages of infection. Previously, we had described the gene expression profile of S. enterica serovar Typhimurium 14028S at the early stage of interaction with Acanthamoeba castellanii. In this study, we have revealed the phase-specific dynamics in expression of several clusters and functional groups of S. Typhimurium 14028S genes. The early stage of invasion characterized by a maximum response to oxidative stress, and it was accompanied by activation of SPI-1 genes, which can contribute to the successful internalization into the host cell. At the second stage (8 h) increase in expression of SPI-2 and SPI-3 genes was accompanied with a maximum expression of iron uptake genes and lysozyme inhibitors. At the late stage of the infection (15 h), downregulation of carbon metabolism and oxidative stress response genes, as well as a decrease in the expression of all other genes, was revealed that may be an evidence of adaptation of Salmonella to intracellular conditions. The obtained results might be useful for further search of factors reducing persistence of pathogens like Salmonella in the environment.</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"270"},"PeriodicalIF":2.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Terrimonas alba sp. nov., an Ochratoxin A-Degrading Strain Isolated from Lakeside Soil.","authors":"Miaohuan Xiong, Huipeng Wu, Jialu Li, Yingying Wan, Xuelan Chen, Bin Liu, Jian He","doi":"10.1007/s00284-025-04254-6","DOIUrl":"10.1007/s00284-025-04254-6","url":null,"abstract":"<p><p>A Gram-negative, aerobic, rod-shaped, and non-motile bacterium, designated strain R1^T, was isolated from lakeside soil in Nanchang, Jiangxi Province, China. Growth was observed at 15-37 °C (optimum 30 °C), pH 6-8 (optimum pH 7) and salinity of 0-1.0% (w/v; optimum 0.5%). Strain R1^T completely degraded 5 mg/L of ochratoxin A within 48 h of incubation. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain R1^T belongs to the genus Terrimonas, and showed 99% sequences similarity with Terrimonas pollutisoli H1YJ31^T. The draft genome of strain R1^T was approximately 6.2 Mb with a 41.5% G + C content. The average nucleotide identity and digital DNA-DNA hybridization values between strain R1^T and T. pollutisoli H1YJ31^T were 90.4% and 41.2%, respectively. The predominant fatty acids of strain R1^T were iso-C_15:0, summed feature 3 (C_16:1 ω6c and/or C_16:1 ω7c), iso-C_17:0 3-OH and iso-C_15:1 G. The major isoprenoid quinone was menaquinone 7 (MK-7). The major polar lipids of strain R1^T were phosphatidylethanolamine, phosphatidylglycerol, a phospholipid, two unidentified glycolipids, two unidentified aminophospholipids, and five unidentified polar lipids. Based on phenotypic, genotypic and phylogenetic evidence, strain R1^T represents a novel species in the genus Terrimonas, for which the name Terrimonas alba sp. nov. is proposed. The type strain is R1^T (= GDMCC 1.4673^T = JCM 37058^T = KCTC 102293^T = KACC 23743^T).</p>","PeriodicalId":11360,"journal":{"name":"Current Microbiology","volume":"82 6","pages":"269"},"PeriodicalIF":2.3,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}