Doklady Biological Sciences最新文献_第3页

In Vitro and In Vivo Biodegradation of Silk Fabric Scaffolds. 真丝织物支架的体外和体内生物降解研究。

Doklady Biological Sciences Pub Date : 2025-02-01 Epub Date: 2025-01-31 DOI: 10.1134/S0012496624600519

I I Agapov, E I Podbolotova, L A Kirsanova, N V Grudinin, A R Pashutin, O I Agapova, A E Efimov, A V Lyundup, S V Gautier

引用次数: 0

Development and Efficacy Evaluation of Multivalent DNA Vaccine against Brucellosis. 布鲁氏菌病多价DNA疫苗的研制及疗效评价

Doklady Biological Sciences Pub Date : 2025-02-01 Epub Date: 2025-01-31 DOI: 10.1134/S0012496624600544

Y M Khodarovich, Maha A Elshazly, W S Shell, S A Nassif, D A Devrishov, S A Magomedova, S N Marzanova, S M Deyev

引用次数: 0

Pedicellate Teeth in Archaic Salamanders (Lissamphibia, Caudata). 古代蝾螈的带蒂牙齿（蝾螈门，尾科）。

Doklady Biological Sciences Pub Date : 2025-02-01 Epub Date: 2025-01-31 DOI: 10.1134/S0012496624600532

P P Skutschas, V V Kolchanov, E V Syromyatnikova

引用次数: 0

Pleistocene Walrus on the Pechora River: Mineralogical and Geochemical Data and Paleoecological Reconstructions. 佩科拉河上更新世海象：矿物地球化学资料和古生态重建。

Doklady Biological Sciences Pub Date : 2025-02-01 Epub Date: 2025-01-31 DOI: 10.1134/S001249662470131X

V I Silaev, I V Smoleva, V N Filippov, S N Shanina, A F Khazov, B A Makeev, D V Kiseleva, A K Fokina, J van der Plicht

{"title":"Pleistocene Walrus on the Pechora River: Mineralogical and Geochemical Data and Paleoecological Reconstructions.","authors":"V I Silaev, I V Smoleva, V N Filippov, S N Shanina, A F Khazov, B A Makeev, D V Kiseleva, A K Fokina, J van der Plicht","doi":"10.1134/S001249662470131X","DOIUrl":"10.1134/S001249662470131X","url":null,"abstract":"Fragments of the left tusk were studied in a Pleistocene walrus whose fossil remains were found on the bank of the Pechora River in 2009. The analyses covered granulometric, chemical, and normative-mineral composition of grounds surrounding the bones; thermal properties and chemical and trace element compositions of the tusk; X-ray diffraction parameters and chemical composition of bone bioapatite; macrostructure and elemental and amino acid compositions of bone organic matter; carbon and oxygen isotopic compositions of bioapatite; and carbon and nitrogen isotope compositions of bone collagen. Bioapatite showed moderately isotopically light carbon, which is characteristic of extracave fossil bones of Pleistocene animals, and isotopically heavy oxygen, which is typical of seawater bicarbonate. The isotopic data obtained for the organic matter of the Pechora walrus correlated with similar characteristics of marine animals, but suggest a fish diet rather than a mollusk diet, which is typical of modern walruses. The finding indicates that the habitat and diet of the Pechora walrus were unusual for marine predators.","PeriodicalId":11351,"journal":{"name":"Doklady Biological Sciences","volume":" ","pages":"49-59"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thioridazine Induces Increase in Expression of the Pyruvate Transporter MPC1 Associated with Immune Infiltration in Malignant Tumors. 硫利达嗪诱导丙酮酸转运体 MPC1 的表达增加与恶性肿瘤的免疫渗透有关

Doklady Biological Sciences Pub Date : 2025-02-01 Epub Date: 2025-01-31 DOI: 10.1134/S001249662460060X

E A Bogomolova, M M Murashko, E M Stasevich, A N Uvarova, E A Zheremyan, K V Korneev, D V Kuprash, D E Demin

{"title":"Thioridazine Induces Increase in Expression of the Pyruvate Transporter MPC1 Associated with Immune Infiltration in Malignant Tumors.","authors":"E A Bogomolova, M M Murashko, E M Stasevich, A N Uvarova, E A Zheremyan, K V Korneev, D V Kuprash, D E Demin","doi":"10.1134/S001249662460060X","DOIUrl":"10.1134/S001249662460060X","url":null,"abstract":"The MPC1 gene is involved in the transport of pyruvate into mitochondria, playing an important role in metabolic processes. Recently, it has been reported that higher MPC1 expression correlates with an increased number of immune cells in human cervical and lung cancers, indicating an enhanced antitumor immune response. Reduced MPC1 levels in gastric tumors are associated with a more severe disease course. Correlational analysis of the MPC1 gene in human lung, hippocampus and frontal cortex tissue samples based on data from the GTEx database revealed associations of this gene with schizophrenia, non-small cell lung cancer, and immune diseases. Our experiments showed that the mRNA level of the MPC1 gene in the non-small cell lung cancer cell line A549 increases 5-fold under the influence of the schizophrenia neuroleptic thioridazine. The observed elevation of MPC1 level may cause tumor infiltration by immune cells, complementing the previously reported data indicating the ability of thioridazine to slow cell growth, induce apoptosis and reduce the ability of cells to migrate.","PeriodicalId":11351,"journal":{"name":"Doklady Biological Sciences","volume":" ","pages":"64-68"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12050224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143370728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of Poloxamer 188 in Carboplatin-Induced Aplastic Anemia Model in CBA Mice. 波洛沙姆188对卡铂所致CBA小鼠再生障碍性贫血模型的影响。

Doklady Biological Sciences Pub Date : 2025-02-01 Epub Date: 2025-01-22 DOI: 10.1134/S0012496624600428

A V Bervinova, V A Palikov, N A Borozdina, I N Kravchenko, I A Pakhomova, R A Dalevich, S Z Hajiguliyeva, E V Arshintseva, S Yu Pushkin, I A Dyachenko, A N Murashev

引用次数: 0

Fatty Acid Content and Lipid Nutritional Indexes in the Antarctic Krill Euphausia superba Collected from Three Regions of the Atlantic Sector of Antarctica. 从南极洲大西洋部分三个地区采集的南极磷虾中的脂肪酸含量和脂质营养指数。

Doklady Biological Sciences Pub Date : 2024-12-01 Epub Date: 2024-10-11 DOI: 10.1134/S0012496624600386

S A Murzina, V P Voronin, D G Bityutskii, N N Nemova

引用次数: 0

Comparative Component Composition of Flowers in Several Syringa Species (Oleaceae). 几种丁香树（油茶科）花的成分比较。

Doklady Biological Sciences Pub Date : 2024-12-01 Epub Date: 2024-09-20 DOI: 10.1134/S0012496624701205

K A Pupykina, N V Polyakova, N V Kudashkina, E V Krasyuk

{"title":"Comparative Component Composition of Flowers in Several Syringa Species (Oleaceae).","authors":"K A Pupykina, N V Polyakova, N V Kudashkina, E V Krasyuk","doi":"10.1134/S0012496624701205","DOIUrl":"10.1134/S0012496624701205","url":null,"abstract":"Because insufficient relevant data are available, the component composition of flowers was studied comparatively in six lilac species of the genus Syringa L. (Oleaceae): S. emodi Wall., S. josikaea Jacg., S. komarowii Schneid., S. reticulata (Blume) H. Hara ssp. amurensis (Rupr.) P. S. Green et M. C. Chang, S. sweginzowii Koehne et Lingelsh, and S. vulgaris L. Plants were from the collection of the South Ural Botanical Garden-Institute. Contents were established for major groups of biologically active substances (BASs): flavonoids, hydroxycinnamic acids, tannins, and organic acids. The highest contents of all BAS groups were observed in S. komarowii flowers: flavonoids, 4.25 ± 0.21%; hydroxycinnamic acids, 6.13 ± 0.29%; tannins, 9.3 ± 0.5%; ascorbic acid, 0.468 ± 0.022%; and organic acids, 10.7 ± 0.5%. The contents were somewhat lower in S. emodi and S. sweginzowii and minimum in S. josikaea. Comparisons of the qualitative and quantitative BAS profiles showed that certain Syringa species cultivated in the Republic of Bashkortostan are promising to further study in terms of their possible use in scientific medicine and the development of herbal remedies.","PeriodicalId":11351,"journal":{"name":"Doklady Biological Sciences","volume":" ","pages":"325-331"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Data on Fungal Species Composition in Spruce Trunk Canker. 云杉树干腐烂病真菌物种组成的新数据。

Doklady Biological Sciences Pub Date : 2024-12-01 Epub Date: 2024-09-20 DOI: 10.1134/S0012496624701229

D A Shabunin, E Yu Varentsova, B G Popovichev, A V Selikhovkin

{"title":"New Data on Fungal Species Composition in Spruce Trunk Canker.","authors":"D A Shabunin, E Yu Varentsova, B G Popovichev, A V Selikhovkin","doi":"10.1134/S0012496624701229","DOIUrl":"10.1134/S0012496624701229","url":null,"abstract":"The composition of canker mycobiota on spruce trunks was studied in the Lisinsky forestry (Leningrad Oblast). Small cankers or canker parts were placed in a humid chamber. Fungi were identified by morphological features. Sorocybe resinae (Fr.) Fr. and Penicillium glaucoalbidum (Desm.) Houbraken & Samson were the most common. The S. resinae occurrence was 75.9 ± 7.9%. The fungus developed in the surface layers of dried resin, but was not detected in the absence of resin production. The fungus S. resinae was therefore assumed to be a nearly ubiquitous component of the mycobiota of resinous cankers on spruce trunks in Leningrad Oblast. The fungus P. glaucoalbidum has only been observed as a saprotroph in Russia earlier. Weak pathogenic properties were detected in the species in experiments; i.e., P. glaucoalbidum grew on live bark tissues in a humid chamber. Based on its high occurrence (41.4 ± 9.1%), P. glaucoalbidum was identified as a regular component of the microbiota in spruce necrotic canker. Pure cultures of P. glaucoalbidum and Oidiodendron sp. were obtained. To test the respective species as possible causative agents of trunk canker, trunks of 20 spruce trees were inoculated with the fungal cultures in a forest stand. The cultures stimulated resin secretion without causing necrosis to spread beyond the inflicted wound. To better understand the phenomenon, a more detailed study of the biota in necrotic cankers is necessary to perform with a special focus on their nonpathogenic part, which has not received proper attention as of yet.","PeriodicalId":11351,"journal":{"name":"Doklady Biological Sciences","volume":" ","pages":"350-355"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pre-Holocene Taymyr Mammoth Petya: Mineralogical, Isotope, and Geochemical Properties of Bones, Soft Tissues, Skin, and Hair and Paleoecological Reconstructions. 前全新世泰米尔猛犸象 Petya：骨骼、软组织、皮肤和毛发的矿物学、同位素和地球化学特性以及古生态重建。

Doklady Biological Sciences Pub Date : 2024-12-01 Epub Date: 2024-09-20 DOI: 10.1134/S0012496624701217

V I Silaev, A S Shuyskiy, I V Smoleva, S N Shanina, E A Vasiliev, D V Kiseleva, A F Khazov, B A Makeev, A E Sukharev, A K Fokina

引用次数: 0