Advanced Functional Materials最新文献_第7页

NIR-II Imaging-Guided Self-Enhanced Nanomedicine With Reactive Oxygen Species Amplification for Type I Photodynamic Therapy of Prostate Cancer NIR-II成像引导自增强纳米药物与活性氧扩增用于I型光动力治疗前列腺癌

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-09 DOI: 10.1002/adfm.202503055

Zhiqian Chen, Zhangxin He, Xiliang Li, Yao Wei, Hongbo Xu, Yuxin Lin, Xuedong Wei, Yuhua Huang, Jianquan Hou, He Wang, Shengliang Li

{"title":"NIR-II Imaging-Guided Self-Enhanced Nanomedicine With Reactive Oxygen Species Amplification for Type I Photodynamic Therapy of Prostate Cancer","authors":"Zhiqian Chen, Zhangxin He, Xiliang Li, Yao Wei, Hongbo Xu, Yuxin Lin, Xuedong Wei, Yuhua Huang, Jianquan Hou, He Wang, Shengliang Li","doi":"10.1002/adfm.202503055","DOIUrl":"https://doi.org/10.1002/adfm.202503055","url":null,"abstract":"Prostate cancer (PCa) is widely perceived as a global health challenge among men, and the overexpression of prostate-specific membrane antigen (PSMA) is closely associated with increased tumor malignancy and metastatic potential. Photodynamic therapy (PDT), which is highly safe and has a low resistance risk, is promising for PCa treatment. However, its efficacy is often hampered by the hypoxic microenvironment and powerful antioxidant system of tumors. Herein, a near-infrared (NIR)-responsive nanomedicine with reactive oxygen species (ROS) amplification is developed for near-infrared II (NIR-II) imaging-guided PSMA-targeted type I PDT of PCa. To construct a self-enhancing nanomedicine, a pure type I photosensitizer PS-6S-Cl with NIR-II fluorescence emission and the thioredoxin 1 inhibitor (Trx-1) are coencapsulated by diselenide-linked liposomes with surface modification of the PSMA ligand. Under NIR irradiation, the PS-6S-Cl in the nanomedicine generated type I ROS to activate Trx-1 release in an NIR-responsive manner. Through the inhibition of Trx-1, the released Trx-1 can efficiently block intracellular ROS depletion to further enhance the efficacy of PDT. In vitro and in vivo experiments confirmed that the NIR-responsive nanomedicine realized NIR-II fluorescence-guided photodynamic immunotherapy (PIT) of PCa with good biosafety. Thus, this study develops a self-enhancing PIT strategy for overcoming immunogenic “cold” tumors.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"90 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144238055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plasmonic RuO2 Coupled with Work Function-Tuned Cu(OH)2 as Cathodes for Enhanced Visible Light-Responsive Zn-Air Batteries 等离子体RuO2耦合功函数调谐的Cu(OH)2阴极用于增强可见光响应的zn -空气电池

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-09 DOI: 10.1002/adfm.202510137

Jiajia Li, Xin Peng, Chenxi Dang, Qiancheng Zhu, Ling Li, Wenming Zhang

{"title":"Plasmonic RuO2 Coupled with Work Function-Tuned Cu(OH)2 as Cathodes for Enhanced Visible Light-Responsive Zn-Air Batteries","authors":"Jiajia Li, Xin Peng, Chenxi Dang, Qiancheng Zhu, Ling Li, Wenming Zhang","doi":"10.1002/adfm.202510137","DOIUrl":"https://doi.org/10.1002/adfm.202510137","url":null,"abstract":"Photo-assisted Zn-air batteries (ZABs) can enhance the kinetics of oxygen reduction and oxygen evolution reactions (ORR/OER); however, issues like rapid charge carrier recombination and limited output voltage persist. Herein, a sandwich-structured photo-assisted ZABs is constructed, in which RuO2 is respectively coupled with a hole transport layer (HTL) (RuO2-HTL) and an electron transport layer (ETL) (RuO2-ETL) as the cathodes, with Zn serving as the anode in the middle. Specifically, HTL and ETL are achieved by interfacial dipoles modulating the work function of Cu(OH)2, whereas photogenerated electrons and holes are originated from the plasmonic effect of RuO2. In the photo-assisted discharge process, the plasmonic-excited holes are pumped by HTL to neutralize the electrons from the Zn anode side, thereby enhancing charge separation. The retained electrons in RuO2 facilitate the ORR process. On the contrary, ETL pumps the plasmon-excited electrons to participate in the reduction of ZnO at the anode, while the holes retained by the extracted RuO2 accelerate the OER. This approach breaks the overpotential barrier in RuO2-based ZABs, achieving a record-high discharge voltage of 1.80 V and an unprecedented low charge voltage of 0.83 V. This novel cathode structure design provides an untapped pathway to obtain the high-performance photo-assisted batteries.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"10 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144238063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing Ion Selectivity Sieving Performance of Cation Exchange Membranes via COF Layer with Sub-1 Nm Charged Channels 带亚1nm电荷通道的COF层增强阳离子交换膜的离子选择性筛选性能

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-09 DOI: 10.1002/adfm.202508966

Xinliang Zhang, Bin Wu, Xueting Zhao, Liang Ge, Jiefeng Pan, Congjie Gao

{"title":"Enhancing Ion Selectivity Sieving Performance of Cation Exchange Membranes via COF Layer with Sub-1 Nm Charged Channels","authors":"Xinliang Zhang, Bin Wu, Xueting Zhao, Liang Ge, Jiefeng Pan, Congjie Gao","doi":"10.1002/adfm.202508966","DOIUrl":"https://doi.org/10.1002/adfm.202508966","url":null,"abstract":"The customized design of the ion transport structure in ion exchange membranes (IEMs) is crucial for achieving efficient ion selective transport. The combination of IEMs with regularly porous materials holds promise for realizing high-performance ion-selective transport. Herein, monovalent selective cation exchange membranes (MSCEMs) are successfully fabricated by constructing a positively charged covalent organic framework (TpTGCl) on the surface of a cation exchange membrane (SPPSU-Cl), with its pore size precisely tailored to 0.78 nm. Benefiting from the unique pore structure of TpTGCl, the resulting composite membranes demonstrated excellent monovalent cation fluxes (1796.42, 1516.06, and 1329.91 mmol m−2 h−1 for K+, Na+, and Li+, respectively), achieved highly efficient separation of monovalent and divalent cations, and exhibited remarkably low modified layer resistance (0.32 Ω cm2). Experiments and molecular dynamics simulations further verified that counterion-mediated positively charged channels effectively enhanced the force difference between monovalent and divalent cations, thereby facilitating the rapid migration of monovalent cations. Interestingly, variations in counterion species within these positively charged channels led to distinct differences in membrane properties. This study proposes a novel channel chemistry-based design strategy for MSCEMs through structural optimization and interfacial engineering, which has significant implications for applications in water treatment, energy storage, and resource recovery.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"6 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144238051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Triazine Engineering in Conjugated Microporous Polymers for Hydrogen Peroxide Photosynthesis 过氧化氢光合作用共轭微孔聚合物中的三嗪工程

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-09 DOI: 10.1002/adfm.202507907

Pan Wang, Fang Ma, Niu Huang, Guijie Liang, Yong Zheng, Lling-Lling Tan, Yan Yan, Mingkai Liu, Liqun Ye

{"title":"Triazine Engineering in Conjugated Microporous Polymers for Hydrogen Peroxide Photosynthesis","authors":"Pan Wang, Fang Ma, Niu Huang, Guijie Liang, Yong Zheng, Lling-Lling Tan, Yan Yan, Mingkai Liu, Liqun Ye","doi":"10.1002/adfm.202507907","DOIUrl":"https://doi.org/10.1002/adfm.202507907","url":null,"abstract":"The photocatalytic synthesis of hydrogen peroxide (H2O2) via synergistic water oxidation (WOR) and oxygen reduction (ORR) dual-channel pathways presents a promising strategy to address global energy and environmental challenges. Herein, two kinds of porous conjugated microporous polymers (CMPs) functionalized with triazinyl and phenyl elements (denoted as TCMPs and PCMPs) are synthesized using a facile one-pot polycondensation strategy. The incorporation of electron-deficient triazine rings (Tz) into the highly conjugated CMPs framework substantially enhances photocatalytic performance. Under natural sunlight using only water and air as reactants, TCMP-1 achieves an exceptional H2O2 generation rate of 783.9 µm h⁻1, representing a 6-fold enhancement over PCMP-1 (130.9 µm h⁻1). Comparative analyses demonstrate that Tz in the donor-acceptor (D-A) system promotes the delocalization of photoexcited charges, promoting efficient electron donation to O2 and thus offering a favorable ORR for H2O2. Furthermore, the electron-deficient nature of the Tz facilitates ORR to form superoxide radicals (·O2⁻), which are key intermediates in H2O2 formation. In situ characterizations combined with theoretical calculations verified the concurrent involvement of ORR and WOR pathways in the H2O2 production process. The findings establish triazine engineering as a universal paradigm for designing high-performance CMP photocatalysts, offering significant avenues for sustainable energy conversion and environmental remediation.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"12 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144238054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thickness-Insensitive Organic Solar Cells with 19.61% Efficiency Processed from All-Hydrocarbon Solvent and Solid Additive 由全碳氢化合物溶剂和固体添加剂制备效率为19.61%的厚度不敏感有机太阳能电池

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-09 DOI: 10.1002/adfm.202503096

Manjun Xiao, Wenjing Zhou, Conggui Jin, Wenyan Su, Sitong Li, Wenqing Zhang, Chao Xu, Hua Tan, Bin Hu, Guanghao Lu, Rui Zhang, Xiaotao Hao, Wei Ma, Qunping Fan

{"title":"Thickness-Insensitive Organic Solar Cells with 19.61% Efficiency Processed from All-Hydrocarbon Solvent and Solid Additive","authors":"Manjun Xiao, Wenjing Zhou, Conggui Jin, Wenyan Su, Sitong Li, Wenqing Zhang, Chao Xu, Hua Tan, Bin Hu, Guanghao Lu, Rui Zhang, Xiaotao Hao, Wei Ma, Qunping Fan","doi":"10.1002/adfm.202503096","DOIUrl":"https://doi.org/10.1002/adfm.202503096","url":null,"abstract":"Organic solar cells (OSCs) have achieved power conversion efficiencies (PCEs) of >20%, although almost all top-performance devices having a thin active layer of ≈100 nm and are being processed with environmentally harmful halogenated solvents/additives. However, attempting to fabricate OSCs with thick active layers from non-halogenated solvents/additives normally leads to dramatically decreased PCEs, seriously restricting their industrialization. To overcome the above shortcomings, it is developed an all-hydrocarbon-based system combined with toluene solvent and fluorene (DBP) solid additive to process active layer (PM6:L8-BO) thickness-insensitive efficient OSCs. Owing to DBP having good planarity, excellent volatility, and stronger interaction with L8-BO, its treated active layers exhibit ordered molecular packing, suitable phase separation, and enhanced charge transport, resulting in a superior PCE of 18.64%. Notably, using D18:BTP-eC9 as the active layer, the OSCs achieve a record-high PCE of 19.61% among the all-hydrocarbon-based system processed devices. Due to the increased crystallinity and optimized hierarchical morphology, the above OSCs show high thickness-tolerance and provide an excellent PCE of ≈18% with a 300 nm active layer, ranking among the highest PCEs for the all-hydrocarbon-based system processed thick-film devices. This work develop an all-hydrocarbon-based system to process active layers in an environmentally friendly way for thickness-insensitive OSCs, with record-high PCEs, toward future industrial production.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"47 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144238049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbon Nanofibers Surface-Exposed with Highly Active Ag Nanoparticles for Enhanced Interfacial Dynamics of Lithium Metal Anodes 碳纳米纤维表面暴露高活性银纳米粒子增强锂金属阳极界面动力学

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-09 DOI: 10.1002/adfm.202506258

Aoming Huang, Hongjiao Huang, Shuo Li, Xiansong Pan, Shichao Sun, Xueming Su, Hongbo Geng, Linlin Li, Maxim Maximov, Jianwei Ren, Shengjie Peng

{"title":"Carbon Nanofibers Surface-Exposed with Highly Active Ag Nanoparticles for Enhanced Interfacial Dynamics of Lithium Metal Anodes","authors":"Aoming Huang, Hongjiao Huang, Shuo Li, Xiansong Pan, Shichao Sun, Xueming Su, Hongbo Geng, Linlin Li, Maxim Maximov, Jianwei Ren, Shengjie Peng","doi":"10.1002/adfm.202506258","DOIUrl":"https://doi.org/10.1002/adfm.202506258","url":null,"abstract":"Lithium metal anodes (LMAs) are widely regarded as a crucial component for the next generation of high-energy-density lithium batteries. The extended pathways for lithium ion diffusion exacerbate concentration polarization, leading to dendrite growth in LMAs. Here, carbon nanofibers with surface-exposed high-activity silver nanoparticles (Ag@CNF) are achieved through the combination of electrospinning and ion exchange techniques, enhancing the interfacial dynamics during lithium storage. Compared to electrodes with encapsulated active sites, the self-supported and binder-free Ag@CNF significantly shortens lithium ion diffusion pathways, reduces nucleation overpotential, and promotes uniform ion diffusion and deposition. Furthermore, this unique structure induces a thinner solid electrolyte interphase (SEI) layer, and greatly reduces the apparent activation energy for charge transfer. Ag@CNF not only enhances atomic utilization efficiency of active centers but also optimizes performance in lithium metal batteries. Notably, assembled full cells demonstrate an excellent retention rate of 90% after 300 cycles at a high capacity of 1.5 mAh cm−2 and a low N/P ratio of 2.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"17 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144238050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conductive Lanthanum Ion-Implanted Zeolite-Supported Amorphous Metal–Organic Frameworks for Oxygen Reduction Reaction 导电镧离子注入沸石负载的非晶态金属-有机骨架氧还原反应

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-09 DOI: 10.1002/adfm.202510605

Xuran Song, Xiaolin Li, Juan He, Wen Zhang, Zhen Zhang

{"title":"Conductive Lanthanum Ion-Implanted Zeolite-Supported Amorphous Metal–Organic Frameworks for Oxygen Reduction Reaction","authors":"Xuran Song, Xiaolin Li, Juan He, Wen Zhang, Zhen Zhang","doi":"10.1002/adfm.202510605","DOIUrl":"https://doi.org/10.1002/adfm.202510605","url":null,"abstract":"Developing efficient and cost-effective non-precious metal catalysts for the oxygen reduction reaction (ORR) is critical to enabling the widespread implementation of metal-air batteries. Amorphous metal–organic frameworks (MOFs) possess the advantages of abundant active sites and tunable electronic structures; however, they face challenges in regulating the chemical environment of metal sites and insufficient stability. Herein, a novel strategy is proposed for the in situ growth of iron-cobalt amorphous MOFs on lanthanum-modified analcime (La Anl). Introducing La into the Anl framework induces framework polarization, increasing the electrical conductivity of Anl by four orders of magnitude. The La Anl framework stabilizes amorphous MOFs, ensures uniform active sites, and boosts conductivity through La atoms incorporation. Moreover, it regulates the iron chemical environment, leading to the partial reduction of Fe3⁺ to Fe2⁺, which enhances ORR activity by promoting oxygen molecule activation and stabilizing the four-electron transfer pathway. Therefore, the prepared FeCoMOFs@La Anl electrocatalyst exhibits excellent ORR activity and durability. The assembled zinc-air battery stably discharges for more than 120 h at 10 mA cm⁻2. This work demonstrates a new approach to designing ORR catalysts by leveraging the unique properties of zeolites and amorphous MOFs, providing new insights into the development of next-generation energy storage systems.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"80 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144238053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Dynamically Programmable Hydrogel Surface with Rapid Magnetically Actuated Snapping of Bistable Dome Configurations 动态可编程水凝胶表面与快速磁驱动的双稳圆顶结构

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-09 DOI: 10.1002/adfm.202508885

Ye Tian, Hao Qi, Zhi Jian Wang, Chen Yu Li, Shaowen Zhu, Yanshen Cai, Ye Qiu, Yi Song, Aiping Liu, Huaping Wu

{"title":"A Dynamically Programmable Hydrogel Surface with Rapid Magnetically Actuated Snapping of Bistable Dome Configurations","authors":"Ye Tian, Hao Qi, Zhi Jian Wang, Chen Yu Li, Shaowen Zhu, Yanshen Cai, Ye Qiu, Yi Song, Aiping Liu, Huaping Wu","doi":"10.1002/adfm.202508885","DOIUrl":"https://doi.org/10.1002/adfm.202508885","url":null,"abstract":"Dynamic shape-morphing soft surfaces are widespread in biological systems and hold great promise for a variety of applications. Despite considerable efforts, challenges remain in achieving fast, repetitive, precise, and contactless control over the desired surface morphing. Here, this work presents a bio-inspired approach that leverages magnetically actuated dome snapping for fast and reprogrammable hydrogel surface morphing. The system consists of a sheet incorporating an array of swelled magnetic gels dispersed within nonswelling regions, forming bistable domes upon swelling. When a magnet approaches the side opposite to the bulking direction of a magnetic gel dome, the dome snaps rapidly toward the magnetic field due to direct magnetic interactions. By tailoring the magnetic threshold for the magnetic dome snapping, adjusting the spatial distribution of magnetic domes within the hydrogel, and precisely controlling the magnetic field, the hydrogel surface can dynamically morph in a programmable, ultrafast, and contactless manner. This work utilizes magnetically actuated surface morphing for dynamic displays, information encryption and decryption, and selective object manipulation. This work is expected to advance magnetically controlled soft robotics with multifunctional smart surfaces, unlocking a wide range of application possibilities.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"26 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144238057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3D-Printed Biomimetic Shape-Memory Rectifier for Smart Directional Transport of Diverse Low-Surface-Tension Liquids and “Chip” Transfer 用于各种低表面张力液体和“芯片”转移的智能定向传输的3d打印仿生形状记忆整流器

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-09 DOI: 10.1002/adfm.202507221

Chuanzong Li, Sizhu Wu, Dayu Li, Liguo Han, Peng Li, Pengcheng Yao, Mingjun Liu, Zengxu Liang, Chenglei Qin, Zhijun Shen, Fei Ding, Longfu Li, Wanqun Chen, Chao Chen

{"title":"3D-Printed Biomimetic Shape-Memory Rectifier for Smart Directional Transport of Diverse Low-Surface-Tension Liquids and “Chip” Transfer","authors":"Chuanzong Li, Sizhu Wu, Dayu Li, Liguo Han, Peng Li, Pengcheng Yao, Mingjun Liu, Zengxu Liang, Chenglei Qin, Zhijun Shen, Fei Ding, Longfu Li, Wanqun Chen, Chao Chen","doi":"10.1002/adfm.202507221","DOIUrl":"https://doi.org/10.1002/adfm.202507221","url":null,"abstract":"The directional transport of low-surface-tension liquids (LSTLs) is crucial in applications such as oil/water separation, electrochemical sensing, and microreactors. However, the development of surfaces capable of the reversible directional manipulation of diverse LSTLs remains challenging. Herein, an LSTL is presented rectifier based on dual-responsive shape-morphing re-entrant microplate arrays (SMRMAs) fabricated via 3D-printed templating. Owing to photothermal and shape-memory effects, the global topography (e.g., bending angle) of the SMRMAs can be reversibly fine-tuned in response to alternating near-infrared rays/mechanical stimuli, thereby realizing the directional steering of diverse LSTLs (e.g., ethanol, n-hexane, ethylene glycol, hexadecane). Fundamental physics combined with simulation analysis provides insights into the underlying mechanism of the directional delivery of LSTLs. The influence of rectifier morphology on the directional spreading behavior of the LSTLs is also studied. An optimized rectifier integrated with the all-in-one SMRMAs can achieve the on-demand dispensation of LSTLs as well as laboratory-on-chip and “chip” mass transfer. Notably, given its shape-morphing capability, the SMRMAs can function as a smart mechanical hand, selectively capturing and releasing objects as needed, thus providing an innovative platform for versatile bifunctional applications. This new technology will be useful in the development of smart microfluidic devices and cross-species manipulators.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"8 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144238062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electroactive Dressing Induces Piezoelectric Signals and Ca2⁺ Activation to Enhance Osteoblast Differentiation and Bone Regeneration in Negative Pressure Therapy 负压治疗中电活性敷料诱导压电信号和Ca2 +激活增强成骨细胞分化和骨再生

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-09 DOI: 10.1002/adfm.202507082

Zhong Zheng, Huiqi Yu, Lu Liu, Junhao Sui, Yijin Hou, Mengchen Chen, Rong Liu, Xiangchao Meng, Chen Ding, Hao Zhang

{"title":"Electroactive Dressing Induces Piezoelectric Signals and Ca2⁺ Activation to Enhance Osteoblast Differentiation and Bone Regeneration in Negative Pressure Therapy","authors":"Zhong Zheng, Huiqi Yu, Lu Liu, Junhao Sui, Yijin Hou, Mengchen Chen, Rong Liu, Xiangchao Meng, Chen Ding, Hao Zhang","doi":"10.1002/adfm.202507082","DOIUrl":"https://doi.org/10.1002/adfm.202507082","url":null,"abstract":"Negative-pressure wound therapy plays a pivotal role in treating open bone fractures. However, the loss of bioelectricity during the healing process significantly delays tissue repair. The generation and maintenance of bioelectric fields require a complex interplay of multiple factors. Previous attempts to regenerate the lost bioelectric field using exogenous conductive materials or supplementing endogenous functional electrolytes have limited success. During this study, a novel electroactive dressing is formulated tailored for negative-pressure therapy by combining piezoelectric poly L-lactic acid doped with bioactive glass and amino-terminated dendritic macromolecules. When subjected to negative pressure, the mechanical deformation of the dressing generates exogenous piezoelectric signals that effectively couple with the endogenous ionic electric fields. Furthermore, the amine-terminated poly(amidoamine) dendritic macromolecules capture cations via coordination and ion-exchange mechanisms, thus retaining electrolytes at the wound site. The findings indicate that the bioelectricity generated by the electroactive dressing under negative pressure facilitates the influx of calcium ions into cells. Calcium ions bind calmodulin, activating Ca2⁺/calmodulin-dependent kinase II, which further activates phosphatidylinositol3-kinase (PI3K), initiating the PI3K/Akt pathway and enhancing osteoblast activity. The efficacy of the developed electroactive dressing is verified using a critical-sized cranial bone-defect model in rats, demonstrating its significant osteogenic differentiation potential. The exogenous and endogenous fields provided by the electroactive dressing maintain the electrophysiological state necessary for bone regeneration, providing a novel therapeutic approach for clinical open fractures.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"257 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144260688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0