Advanced Functional Materials最新文献

Histidine‐Engineered ZIF‐8 Nanoparticles for High‐Efficiency siRNA Delivery and Gene Therapy of Intervertebral Disc Degeneration 组氨酸工程ZIF - 8纳米颗粒用于高效siRNA传递和椎间盘退变的基因治疗

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-23 DOI: 10.1002/adfm.202504775

Sunlong Li, Siyu Hu, Yifeng Shi, Yeheng Huang, Yuli Chen, Yan Chen, Fengyu Zhang, Zhan Gao, Shuqing Jin, Qiwei Zhou, Shu Yang, Haibo Liang, Lianggao Yu, Shuhao Zhang, Chongan Huang, Chenglong Xie, Zaher Meftah, Aimin Wu, Xiaolei Zhang, Xiangyang Wang

{"title":"Histidine‐Engineered ZIF‐8 Nanoparticles for High‐Efficiency siRNA Delivery and Gene Therapy of Intervertebral Disc Degeneration","authors":"Sunlong Li, Siyu Hu, Yifeng Shi, Yeheng Huang, Yuli Chen, Yan Chen, Fengyu Zhang, Zhan Gao, Shuqing Jin, Qiwei Zhou, Shu Yang, Haibo Liang, Lianggao Yu, Shuhao Zhang, Chongan Huang, Chenglong Xie, Zaher Meftah, Aimin Wu, Xiaolei Zhang, Xiangyang Wang","doi":"10.1002/adfm.202504775","DOIUrl":"https://doi.org/10.1002/adfm.202504775","url":null,"abstract":"Ferroptosis is a major contributor to intervertebral disc degeneration (IVDD) and represents a promising therapeutic target; however, effective medications that specifically target ferroptosis are still lacking. Consequently, strategies aimed at suppressing the expression of ferroptosis‐related genes, such as small interfering RNA (siRNA) targeting activating transcription factor 3 (ATF3), appear to be a feasible therapeutic approach for IVDD. Zeolitic imidazolate framework‐8 (ZIF‐8) exhibits exceptionally high binding affinity for nucleic acids, including siRNA. Nevertheless, its practical application is hindered by challenges such as limited siRNA encapsulation and potential toxicity arising from Zn2⁺ ion release during degradation. In the current study, a novel siRNA delivery system is designed with low toxicity, high encapsulation efficiency, and sustained release by hybridizing classical ZIF‐8 with histidine (H‐ZIF‐8) through defect engineering. In vitro functional studies demonstrated that H‐ZIF‐8 significantly enhances the delivery efficiency of siATF3 in nucleus pulposus cells (NPCs), and effectively suppresses ferroptosis and extracellular matrix (ECM) degradation. Furthermore, the incorporation of histidine into ZIF‐8 may improve its biocompatibility by reducing the proportion of Zn2⁺ ions present. In vivo, siATF3@H‐ZIF‐8 significantly inhibited ferroptosis and alleviated intervertebral disc degeneration (IVDD) in a rat model through sustaining ATF3 knockdown. This research suggests that histidine‐modified ZIF‐8 may serve as a novel system for siRNA delivery and an effective gene therapy method for diseases, including IVDD.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"36 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144341077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecularly Engineered Quaternized κ‐Carrageenan: a Multifunctional Platform for Atmospheric Water Harvesting, Moisture‐Electricity Generation, and Self‐powered Wearable Sensors 分子工程季铵盐化κ‐卡拉胶：一种用于大气水收集、水分发电和自供电可穿戴传感器的多功能平台

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-23 DOI: 10.1002/adfm.202502668

Na Li, Xiao Yu, Da‐Peng Yang, Jintao He

{"title":"Molecularly Engineered Quaternized κ‐Carrageenan: a Multifunctional Platform for Atmospheric Water Harvesting, Moisture‐Electricity Generation, and Self‐powered Wearable Sensors","authors":"Na Li, Xiao Yu, Da‐Peng Yang, Jintao He","doi":"10.1002/adfm.202502668","DOIUrl":"https://doi.org/10.1002/adfm.202502668","url":null,"abstract":"The pursuit of sustainability in the energy and environmental fields, coupled with the innovation in intelligent wearable sensing technologies, demands high‐performance materials with advanced functionalities. Molecular design has emerged as a cornerstone for optimizing material properties and achieving multifunctional integration. Natural carrageenan, a green substrate material known for its biocompatibility and renewability, faces challenges due to its limited processability and mechanical robustness. In this study, zwitterionic groups are introduced through molecular design to regulate intermolecular interactions, significantly lowering the sol–gel transition temperature, thus enabling superior processability and enhanced mechanical properties. This modification strategy enables efficient salt ion immobilization, endowing the material with outstanding atmospheric water harvesting (AWH) capabilities (2.1 g g−¹) and stable moisture‐electricity generation (MEG) performance (0.9 V of Voc). Leveraging these advancements, a self‐powered smart sensor is developed, capable of real‐time monitoring of respiratory states, pressure sensing, and rapid response to noncontact actions. This work provides an integrated material design framework that facilitates innovation in green energy and personalized health monitoring technologies.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"18 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144341079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Roll‐To‐Roll Coating to Processing Large‐Area Zinc Anodes toward Fast and Dendrite‐Free Deposition 卷对卷涂层用于处理大面积锌阳极，以实现快速和无枝晶沉积

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-23 DOI: 10.1002/adfm.202509206

Huanyan Liu, Huanhuan Sun, Wei Hua, Xiangjiang Liu, Wenbo Liu, Jian‐Gan Wang

{"title":"Roll‐To‐Roll Coating to Processing Large‐Area Zinc Anodes toward Fast and Dendrite‐Free Deposition","authors":"Huanyan Liu, Huanhuan Sun, Wei Hua, Xiangjiang Liu, Wenbo Liu, Jian‐Gan Wang","doi":"10.1002/adfm.202509206","DOIUrl":"https://doi.org/10.1002/adfm.202509206","url":null,"abstract":"Surface modification has emerged as a promising approach for manipulating uniform Zn deposition and long‐life aqueous Zn batteries. However, challenges related to the complicated fabrication processes and high cost hinder the scale‐up deployment of zinc anodes. Herein, a versatile low‐cost roll‐to‐roll coating methodology is demonstrated for expeditiously processing large‐area Zn anode. Through a simple liquid‐air interfacial deposition and Lewis acid‐base coordination, a functional nanofilm can be in situ anchored to the Zn anode to enable planar Zn deposition by providing rich ion migration pathways, homogeneous electric field distribution, and enhanced ion diffusion kinetics. In addition, the water‐related side reactions are simultaneously inhibited due to the desolvation effect of the nanofilm. The as‐modified Zn anode manifests high Coulombic efficiency up to 99.9% for 1500 cycles, a long lifetime over 2700 h, and a high cumulative capacity of 6.25 Ah cm−2. Furthermore, the practical feasibility is verified by the remarkable cycling capability in Zn||MnO2 pouch cells. This study presents a cost‐effective and scalable roll‐to‐roll strategy to fabricating large‐area Zn anodes for boosting the practical application of aqueous Zn batteries.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"18 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144341068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultra‐Thin Lithium–Phosphorus–Sulfur (LPS) Interfacial Electrolyte Layer for All‐Solid‐State Lithium Metal Battery with High‐Rate and High‐Areal‐Capacity Performance 具有高倍率和高面积容量性能的全固态锂金属电池的超薄锂磷硫（LPS）界面电解质层

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-23 DOI: 10.1002/adfm.202509820

Yu Su, Yuxi Deng, Yu Luo, Zhaoyu Rong, Yuteng Fan, Cong Zhong, Fucheng Ren, Xiangsi Liu, Yuqi Wu, Kangjun Wang, Yong Cheng, Haoyue Zhong, Jun Zhao, Mingsheng Wang, Xuefeng Wang, Jianyu Huang, Jiawei Yan, Yong Yang

{"title":"Ultra‐Thin Lithium–Phosphorus–Sulfur (LPS) Interfacial Electrolyte Layer for All‐Solid‐State Lithium Metal Battery with High‐Rate and High‐Areal‐Capacity Performance","authors":"Yu Su, Yuxi Deng, Yu Luo, Zhaoyu Rong, Yuteng Fan, Cong Zhong, Fucheng Ren, Xiangsi Liu, Yuqi Wu, Kangjun Wang, Yong Cheng, Haoyue Zhong, Jun Zhao, Mingsheng Wang, Xuefeng Wang, Jianyu Huang, Jiawei Yan, Yong Yang","doi":"10.1002/adfm.202509820","DOIUrl":"https://doi.org/10.1002/adfm.202509820","url":null,"abstract":"To solve the challenging interfacial issues of all‐solid‐state lithium batteries (ASSLBs), a novel strategy to construct a nano‐scale lithium‐phosphorus‐sulfur (LPS) electrolyte film by atomic layer deposition (ALD) technique and to coat it on Li6PS5Cl (LPSCl) electrolyte is proposed and demonstrated for the first time. The modified LPS@LPSCl electrolytes exhibit excellent compatibility with both high‐voltage cathodes and pure lithium metal anode with enhanced ionic conductivity, much reduced electronic conductivity, and modified mechanical strength, which can fill the gaps in the base electrolytes after electrolyte pellet pressing and reduce interfacial defects in the composite electrolytes. The sulfide‐based ASSLBs, assembled with LPS@LPSCl, Al‐GL@NCM811 materials, and a lithium indium anode, achieves a high areal capacity of 10.6 mAh cm−2 at high‐temperature and high mass loading (60 °C, 51.9 mg cm−2). Additionally, LPS@LPSCl has high stability toward lithium metal, suppressing interfacial side reactions and improving physical contact, enabling charge and discharge testing at a high current density of 1.5 mA cm−2. This study demonstrates that the nano‐scaled film formation of sulfide solid‐state electrolytes can significantly reduce the polarization voltage of traditional double‐layer electrolytes toward lithium metal, and provide a new approach for interfacial modification in sulfide solid‐state batteries.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"32 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144341071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giant Negative Compressibility in 2D Hybrid Perovskites via Configuration Transition and Rotation of Carbon Chains 二维杂化钙钛矿中碳链构型转变和旋转的巨大负压缩性

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-23 DOI: 10.1002/adfm.202505304

Pengfei Shen, Chunguang Zhai, Donghao Xu, Yongtao Zou, Quanjun Li, Mingguang Yao, Bingbing Liu

{"title":"Giant Negative Compressibility in 2D Hybrid Perovskites via Configuration Transition and Rotation of Carbon Chains","authors":"Pengfei Shen, Chunguang Zhai, Donghao Xu, Yongtao Zou, Quanjun Li, Mingguang Yao, Bingbing Liu","doi":"10.1002/adfm.202505304","DOIUrl":"https://doi.org/10.1002/adfm.202505304","url":null,"abstract":"Applying compressive force typically causes materials to shrink (or expand under tension). Materials that exhibit anomalous volume expansion upon compression (VEUC) present significant challenges and are the subject of extensively research. Here, it is discovered that (C8H17NH3)2PbBr4 (C8PbBr4), a 2D perovskite constructed by inorganic ‐[PbBr6]‐ connected by C chains, displays an abnormal volume expansion ratio of 12.9% under external compression. The giant VEUC results from the configurational change of C chains from initial parallel arrays to herringbone‐like arrays, accompanying with the rotation of C chains and the formation of tail‐to‐tail interaction in the herringbone‐like arrays due to a charge reinjection from chains to ‐[PbBr6]‐, which subsequently expand the crystal lattice. These comparative experiments reveal that the VEUC in CnPbBr4 is chain length‐dependent, which is not obvious in those with C4‐ and C12‐chains. These findings on VEUC driven by configurational change of carbon chains open up a new avenue to explore synthetic materials with anomalous piezo‐mechanical properties for potential applications, such as smart body armors and artificial muscles.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"101 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144341074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In Situ Construction of MXene Derivatives and Rare Metal Doping in Nanofibers for Multifunctional and Ultrathin Electromagnetic Responses MXene衍生物的原位构建和稀有金属掺杂在纳米纤维中用于多功能和超薄电磁响应

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-23 DOI: 10.1002/adfm.202510047

Jun Huang, Xiaojun Zeng, Xiao Jiang, Xiaomei Deng, Zhanming Wu, Yanfeng Gao

{"title":"In Situ Construction of MXene Derivatives and Rare Metal Doping in Nanofibers for Multifunctional and Ultrathin Electromagnetic Responses","authors":"Jun Huang, Xiaojun Zeng, Xiao Jiang, Xiaomei Deng, Zhanming Wu, Yanfeng Gao","doi":"10.1002/adfm.202510047","DOIUrl":"https://doi.org/10.1002/adfm.202510047","url":null,"abstract":"Electromagnetic systems capable of achieving multifunctional integration are essential for advancements in electromagnetic protection. Herein, a 1D PCN/MXene‐TiO2‐RM (RM = Gd, Ce, Pr, Er, Sm) nanocomposite nanofiber is meticulously designed with a 3D spatial network structure. During the heat treatment process, polyacrylonitrile (PAN) is carbonized to nitrogen‐doped carbon (PCN) to form 1D nanofibers with excellent conductive pathways and high conductivity. MXene is in situ oxidized to rutile phase TiO2, forming a heterogeneous interface and regulating the dielectric constant. At the same time, the incorporated rare metal further balances the dielectric constant of the nanofiber and promotes the EMW attenuation ability. Therefore, at ultrathin matching thickness of 1.7, 2.245, and 2.88 mm, PCN/MXene‐TiO2‐Gd inherits strong reflection loss (RL) of −64.01, −71.32, and −65.4 dB, respectively, covering the Ku, X, and C bands, demonstrating its outstanding EMW response characteristics. Further investigation reveals the universality of this strategy, as doping with other rare metals (Ce, Pr, Er, Sm) also significantly improved the performance of PCN/MXene‐TiO2 nanofibers. Additionally, the designed 1D nanofibers also exhibit multifunctional properties such as lightweight, flexibility, hydrophobicity, seawater corrosion resistance, heat dissipation, and radar stealth.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"25 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144341075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microplate Active Migration Emerging From Light‐Induced Phase Transitions in a Nematic Liquid Crystal 向列型液晶中光诱导相变引起的微孔板主动迁移

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-23 DOI: 10.1002/adfm.202504046

Antonio Tavera‐Vázquez, Danai Montalvan‐Sorrosa, Gustavo R. Perez‐Lemus, Otilio E. Rodriguez‐Lopez, Jose A. Martinez‐Gonzalez, Vinothan N. Manoharan, Juan J. de Pablo

{"title":"Microplate Active Migration Emerging From Light‐Induced Phase Transitions in a Nematic Liquid Crystal","authors":"Antonio Tavera‐Vázquez, Danai Montalvan‐Sorrosa, Gustavo R. Perez‐Lemus, Otilio E. Rodriguez‐Lopez, Jose A. Martinez‐Gonzalez, Vinothan N. Manoharan, Juan J. de Pablo","doi":"10.1002/adfm.202504046","DOIUrl":"https://doi.org/10.1002/adfm.202504046","url":null,"abstract":"Achieving precise control over the diverse equilibrium configurations and corresponding optical textures of motile liquid crystals (LCs) in response to a wide range of external stimuli is a formidable challenge. This complexity becomes even more intriguing when applied to far‐from‐equilibrium systems. In this work, we investigate how LC phase transitions are leveraged to achieve controlled self‐propulsion of colloids. To accomplish that, we designed quasi‐2D solid, micron‐sized, light‐absorbing platelets suspended in a thermotropic nematic LC. When exposed to light, these platelets self‐propel, generating localized nematic‐isotropic (NI) phase transitions. The system's dynamics are governed by temperature, light intensity, and confinement, giving rise to three regimes: a large 2D regime where the platelet‐isotropic phase bubble remains stationary with a stable NI interface; a compact motile‐2D regime where the NI interface is closer to the platelet; and a motile‐3D confinement regime, marked by the appearance of multipolar LC configurations. Furthermore, we employed continuum mean‐field simulations to predict stable platelet‐LC states in slab confinements. The approach gives insights crucial for designing far‐from‐equilibrium synthetic systems with controlled propulsion and tunable topological reconfigurations. This has implications for advancements in photonics and material sciences.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"8 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144341076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Creating Smart Washable Flooring: Sandwich-Style Single-Electrode Triboelectric Nanogenerator with Barium Titanate and Graphite-Fluorinated Polymer-Infused Ecoflex Hybrid Composites for Enhanced Safety and Security (Adv. Funct. Mater. 24/2025) 创造智能可洗地板：三明治式单电极摩擦电纳米发电机与钛酸钡和氟化石墨聚合物注入Ecoflex混合复合材料，增强安全性和安全性（Adv.功能）。板牙。24/2025)

IF 18.5 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-22 DOI: 10.1002/adfm.202570144

Jae Uk Yoon, Insun Woo, Prasad Gajula, Jin Woo Bae

引用次数: 0

Magnetic Field Driven Ceria Nanosystems for Mitochondria Targeted Therapy of Ischemic Stroke (Adv. Funct. Mater. 24/2025) 磁场驱动的氧化铈纳米系统用于缺血性脑卒中线粒体靶向治疗。板牙。24/2025)

IF 18.5 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-22 DOI: 10.1002/adfm.202570145

Jun Liao, Wenxiu He, Shiming Zhang, Jingya Wang, Hansen Cheng, Lidong Gong, Yanglonghao Li, Yuhan Sun, Dan Lu, Chuan Zhang, Ying Lu, Qiang Zhang, Zhiqiang Lin

引用次数: 0

Pickering Emulsion for Enhanced Viability of Plant Growth Promoting Bacteria and Combined Delivery of Agrochemicals and Biologics (Adv. Funct. Mater. 24/2025) 酸洗乳剂提高植物促生菌活力及农药与生物制剂联合施用的研究板牙。24/2025)

IF 18.5 1区材料科学

Advanced Functional Materials Pub Date : 2025-06-22 DOI: 10.1002/adfm.202570139

Mariam Sohail, John Cheadle, Rishum Khan, Hrishikesh Mane, Khandoker Samaher Salem, Katie Ernst, Adriana San Miguel, Charles H. Opperman, Tahira Pirzada, Nathan Crook, Saad A. Khan

引用次数: 0