一种鼻内纳米药物作为有效的广谱病毒抑制剂和准疫苗。板牙。28/2025)

IF 18.5 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Functional Materials Pub Date : 2025-07-21 DOI:10.1002/adfm.70262

Jingran Chen, Ying Li, Li Xiao, Zhanchen Guo, Weihua Lu, Jin Huang, Jizong Li, Bin Li, Zhen Liu

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引用次数: 0

摘要

在2501533号文章中，李斌、刘震等人提出了一种全新的抗病毒概念，将抗病毒药物和疫苗结合起来，同时提供快速的病毒抑制和长期的预防。精心设计的光热纳米药物具有多种抗病毒机制，包括广谱病毒结合、阻断病毒细胞附着、诱导病毒聚集、增强巨噬细胞吞噬、促进病毒粒子裂解和启动免疫应答。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

An Intranasal Nanomedicine Functions as Both Potent Broad-spectrum Viral Inhibitor and Quasi-Vaccine (Adv. Funct. Mater. 28/2025)

查看原文本刊更多论文

An Intranasal Nanomedicine Functions as Both Potent Broad-spectrum Viral Inhibitor and Quasi-Vaccine (Adv. Funct. Mater. 28/2025)

Photothermal Nanomedicine

In article number 2501533, Bin Li, Zhen Liu, and co-workers present a brand-new antiviral concept that integrates antivirals and vaccines for providing rapid viral inhibition and long-term prevention simultaneously. The elaborately designed photothermal nanomedicine exerts multiple antiviral mechanisms including broad-spectrum virus binding, blocking virus-cell attachment, inducing viral aggregation, enhancing macrophage phagocytosis, promoting virions lysis, and initiating immune response.

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来源期刊

Advanced Functional Materials 工程技术-材料科学：综合

CiteScore

29.50

自引率

4.20%

发文量

2086

审稿时长

2.1 months

期刊介绍： Firmly established as a top-tier materials science journal, Advanced Functional Materials reports breakthrough research in all aspects of materials science, including nanotechnology, chemistry, physics, and biology every week. Advanced Functional Materials is known for its rapid and fair peer review, quality content, and high impact, making it the first choice of the international materials science community.