Dentistry Journal最新文献

{"title":"Malocclusion and Its Relationship with Sound Speech Disorders in Deciduous and Mixed Dentition: A Scoping Review.","authors":"Mariangela Aprile, Alessio Verdecchia, Claudia Dettori, Enrico Spinas","doi":"10.3390/dj13010027","DOIUrl":"10.3390/dj13010027","url":null,"abstract":"<p><p><b>Objectives:</b> The intricate relationship between malocclusions and speech sound disorders (SSDs) is yet to be fully understood. This is particularly true for pediatric patients during the deciduous and mixed dentition stages. Employing a methodical scoping review approach, this study scrutinizes the recent literature to elucidate how these dental misalignments impact speech articulation and phonetic clarity. <b>Methods:</b> The present scoping review has been conducted following the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines. The selected articles have been found using PubMed, Scopus, Web of Science, and The Cochrane Library; the scope was limited to studies describing cases of patients in the deciduous or mixed dentition stage and the presence of both malocclusion and SSDs. <b>Results:</b> Out of the 1880 articles found, 44 passed the initial screening and 12 met the eligibility criteria and have been included in this review. <b>Conclusions:</b> The analysis reveals that while there is a consensus on the influence of malocclusions on speech production, the extent and specific nature of these effects vary across studies. anterior open bite is frequently associated with speech disorders, affecting phonemes by altering airflow and tongue placement. The review highlights the need for multidisciplinary approaches for effective treatment and calls for further investigation into the causative relationships between malocclusions and SSDs.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11764062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Awareness, and Influence of the COVID-19 Pandemic on Students of Biomedical Faculties: A Cross-Sectional Study.","authors":"Bruno Špiljak, Luka Šimunović, Ana Marija Miličević, Marko Granić, Lana Bergman, Jasminka Peršec","doi":"10.3390/dj13010028","DOIUrl":"10.3390/dj13010028","url":null,"abstract":"<p><p><b>Background/Objectives</b>: The COVID-19 pandemic has had a profound impact on physical, mental, and social aspects of life worldwide. This study aimed to explore and compare differences in knowledge, awareness, behavior, and the psychological impact of the pandemic among students of biomedical faculties at the University of Zagreb. <b>Methods</b>: A cross-sectional study was conducted between 27 November 2020 and 19 January 2021 involving 518 students from the School of Dental Medicine, School of Medicine, Faculty of Pharmacy and Biochemistry, and Faculty of Veterinary Medicine. An anonymous online questionnaire was distributed, assessing participants' knowledge about SARS-CoV-2, information sources, attitudes, and psychological responses. Data were analyzed using descriptive statistics and appropriate statistical tests. <b>Results</b>: The median knowledge score was 61.54%, with senior and female students demonstrating significantly more knowledge (<i>p</i> < 0.001 and <i>p</i> = 0.044, respectively). Students who consulted the scientific literature and official websites had higher knowledge levels (<i>p</i> < 0.001). Most participants used media and social networks for pandemic information, while scientific sources were underutilized. Psychological impacts were evident, with 46.3% expressing fear about the future and 25% reporting anxiety if they were to be infected. Additionally, those who engaged with the scientific literature were more likely to accept vaccination and showed lower levels of COVID-19 stigma. A majority (64.5%) believed that the media exaggerated the pandemic's risks. <b>Conclusions</b>: Biomedical students demonstrated moderate knowledge about COVID-19, with a clear link between scientific literacy and more informed, less stigmatizing attitudes. This study underscores the importance of reliable information sources in shaping public health awareness and highlights the need for further education on COVID-19 symptoms and preventive measures.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143031965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional Epidemiological Study on the Dental Status of the First Permanent Molar in Romanian Schoolchildren.","authors":"Liana Beresescu, Gabriela Felicia Beresescu, Daniela Esian, Alexandru Vlasa, Csilla Benedek, Raluca Sabau, Alexandra Mihaela Stoica","doi":"10.3390/dj13010026","DOIUrl":"10.3390/dj13010026","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Dental caries remains a significant public health challenge in Romania, with recent studies reporting a prevalence of 40% in children's permanent teeth, with 90% of cases untreated. This study aimed to evaluate the dental status of the first permanent molars in children aged 11-12 years. <b>Methods:</b> This cross-sectional study was conducted over 12 months at the Integrated Center for Dental Medicine in Târgu Mureș and two private clinics in Transylvania. A total of 516 children, aged 11-12 years, were examined using the ICDAS II classification. Data on carious lesions and dental treatments performed were collected. <b>Results:</b> Of the 2064 first permanent molars examined, 57.99% had carious lesions, fillings, or extractions, while 41.28% were free from caries. Among the affected molars, 41.71% had untreated caries, 9.30% were filled, and 6.25% were sealed. Boys showed a significantly higher prevalence of advanced lesions (ICDAS 4-6) compared to girls. Caries predominantly affected the pits and fissures (87.46%). <b>Conclusions:</b> This study reveals a high prevalence of carious lesions in first permanent molars and a low rate of treatment. The findings emphasize the need for improved oral health education, increased access to dental care, and the development of national strategies to prevent and treat dental caries in children.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to Deal with Pulpitis: An Overview of New Approaches.","authors":"Jakub Fiegler-Rudol, Wojciech Niemczyk, Katarzyna Janik, Anna Zawilska, Małgorzata Kępa, Marta Tanasiewicz","doi":"10.3390/dj13010025","DOIUrl":"10.3390/dj13010025","url":null,"abstract":"<p><p><b>Background:</b> Traditional root canal therapy (RCT) effectively removes diseased or necrotic pulp tissue and replaces it with inorganic materials. Regenerative endodontics is an alternative to conventional RCT by using biologically based approaches to restore the pulp-dentin complex. This review explores emerging techniques, including autogenic and allogenic pulp transplantation, platelet-rich fibrin, human amniotic membrane scaffolds, specialized pro-resolving mediators, nanofibrous and bioceramic scaffolds, injectable hydrogels, dentin matrix proteins, and cell-homing strategies. These methods utilize stem cells, growth factors, and biomaterials to regenerate vascularized, functional pulp tissue. <b>Methods:</b> A narrative review was conducted using PubMed, Scopus, and Embase to identify studies published between 2010 and 2023. In vitro, animal, and clinical studies focusing on innovative regenerative endodontic techniques were analyzed. <b>Conclusions:</b> Although regenerative endodontics demonstrates great potential, challenges remain in standardizing protocols, addressing biological variability, and achieving consistent clinical outcomes. Future research must focus on refining these techniques to ensure their safety, efficacy, and accessibility in routine practice. By addressing current limitations, regenerative endodontics could redefine the management of pulpitis, offering biologically based treatments that enhance tooth vitality, structural integrity, and long-term prognosis.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11764427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143031618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socket Sealing Using Free Gingival Grafts: A Randomized Controlled Trial.","authors":"Ralitsa Yotsova","doi":"10.3390/dj13010024","DOIUrl":"10.3390/dj13010024","url":null,"abstract":"<p><p><b>Background:</b> Post-extraction ridge resorption is an inevitable phenomenon that cannot be eliminated but is significantly reduced using additional surgical techniques known as socket preservation. They aim to create favorable conditions for implant placement and prosthetic restoration. This study aims to assess the effect of socket sealing (SS) with free gingival grafts on the vertical resorption of socket walls at the premolar and molar regions over 3 months. <b>Methods:</b> This randomized two-arm controlled trial with parallel groups (1:1 allocation) was conducted at the Department of Oral Surgery, Medical University-Varna, Bulgaria, from 27 June 2022 to 20 April 2023. Forty patients aged 30-65 were equally and randomly allocated to the SS or the control groups. Atraumatic tooth extraction was performed. In the control group, the socket was left on secondary wound healing. In the SS group, the socket orifice was \"sealed\" with an FGG harvested from the hard palate or maxillary tuberosity. <b>Results:</b> Data analysis demonstrated that SS with an FGG is a successful method for reducing the post-extraction resorption of the socket walls. In addition, this study confirms that the thickness of the buccal wall is a significant factor in its vertical resorption. <b>Conclusions:</b> Socket sealing with an FGG is a valuable method that eliminates the need for flap reflection and compensates for the soft tissue deficit when immediate implant placement or bone augmentation is required. Further research is necessary to determine the role of different factors influencing bone resorption and compare the effect of different socket preservation methods.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Association Between Third Molar Agenesis and Carabelli Traits: A Cross-Sectional Study.","authors":"Isabela Ribeiro Madalena, Heloisa Guimarães Resende, Ariane Beatriz Blancato, Maria Angélica Hueb de Menezes-Oliveira, Flares Baratto-Filho, Poliana Ferreira Santos, Camila Paiva Perin, Thais Vilalba Paniagua Machado do Nascimento, Peter Proff, Christian Kirschneck, César Penazzo Lepri, Erika Calvano Küchler","doi":"10.3390/dj13010023","DOIUrl":"10.3390/dj13010023","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Dental agenesis is the congenital absence of at least one tooth and has been associated with several other developmental dental conditions, such as morphological dental alterations and Carabelli trait. This study sought to investigate whether third molar agenesis is associated with Carabelli traits in permanent molars. <b>Methods</b>: This was a cross-sectional study that used a convenience sample obtained from the orthodontic records of German patients. Patients with syndromes, oral clefts, congenital alterations including dental agenesis (except agenesis of third molars), and severe cases of bruxism with a loss of tooth tissue were excluded. Teeth with cavitated lesions of dental caries, occlusal wear, restorations, and evident dental deformities were not included in the evaluation. The Carabelli trait was evaluated in the permanent maxillary molars. The Carabelli trait was classified according to its expression for each tooth as either absent, negative, and positive expressions. Third molar agenesis was evaluated only in patients older than 10 years old (based on when initial tooth formation should be visible in the panoramic radiographs). The two-sided Chi-squared test was used to investigate the association between the conditions, using an alpha of 5% (<i>p</i> < 0.05). <b>Results</b>: A total of 155 patients (74 females and 81 males) were investigated; 39 had third molar agenesis and 75 had the Carabelli trait. There was no statistical significance difference between patients with third molar agenesis and those with Carabelli traits in relation to sex (<i>p</i> > 0.05). The Carabelli trait was more common in first molars than in second molars. There was no statistical significant association between third molar agenesis and Carabelli traits (<i>p</i> > 0.05). <b>Conclusions</b>: Third molar agenesis was not associated with the Carabelli trait in the permanent molars in this population.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Viewing Modality Affect Frontal Mandibular Bone Height Measurement? A Comparison Between 3D Digital Imaging and Communications in Medicine Viewer and Printed Portable Document Format Cone Beam Computer Tomography Reports.","authors":"Michael Solomonov, Yoav Shapinko, Ella Lalum, Joe Ben Itzhak, Sapir Argaman, Matan Schottig, Amit Halpern, Nirit Yavnai, Idan Stiklaru","doi":"10.3390/dj13010022","DOIUrl":"10.3390/dj13010022","url":null,"abstract":"<p><p><b>Objectives:</b> Buccal cortical bone dimensions are crucial in dental radiology, as they impact orthodontic treatment outcomes. Changes in alveolar bone dimensions can result in malocclusion and require interdisciplinary approaches for correction. The accurate quantification of buccal bone dimensions is crucial for appropriate treatment planning and avoiding medico-legal issues. This study aimed to compare buccal bone height measurements between three-dimensional (3D) digital imaging and communications in medicine (DICOM) data and portable document format (PDF) cone beam computer topography reports for mandibular frontal teeth, testing the hypothesis of no difference in values between the two modalities. <b>Methods:</b> Each of the five observers performed a total of 720 height measurements (360 by DICOM and 360 by PDF), yielding a total of 3600 measurements overall. <b>Results:</b> Compared with the DICOM format, using PDF files was associated with a significantly greater rate of inability to carry out the measurements (8.8% vs. 3%, respectively, <i>p</i> < 0.001, chi-square). The average buccal bone height measured in the DICOM was 11.51 mm, which was significantly greater than the 10.35 mm measured in the PDF (<i>p</i> < 0.001). The mean height measured by the DICOM was consistently greater than that measured by the PDF, with highly significant differences in the findings of four of the examiners (<i>p</i> < 0.001). <b>Conclusions:</b> Viewing modality significantly affected the height of the buccal bone in the frontal mandibular area. Compared with the generated PDF reports, the 3D DICOM viewer performed better than the printed PDF and enabled more measurements in the target area.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Practices, and Attitudes Towards Silver Diamine Fluoride Therapy Among Dentists and Students in Southeastern Spain.","authors":"Clara Serna-Muñoz, Marina Lucas-Porras, Yolanda Martínez-Beneyto, Amparo Pérez-Silva, Francisco Javier Ibañez-López, Antonio José Ortiz-Ruiz","doi":"10.3390/dj13010020","DOIUrl":"10.3390/dj13010020","url":null,"abstract":"<p><p><b>Background/Objectives:</b> The use of silver diamine fluoride (SDF) has increased in recent years for the management of caries lesions in children and adults. The aim of this study is to determine the level of knowledge and the attitude of Spanish dentists (GDPs) and final-year dental students (DSs) regarding the use of SDF. <b>Methods:</b> A cross-sectional survey (questionnaire) was carried out aimed at final-year dental students (DSs) (n = 43) and registered dentists (GDPs) (n = 1050) in the autonomous community of the region of Murcia (Spain). <b>Results:</b> the response rates were GDPs 7.7% (n = 81) and DSs 84.5% (n = 38). Only 20.98% of GDP respondents reported having been trained on SDF versus 100% of DSs. Significant differences were observed between the groups (<i>p</i> < 0.05). While 94.7% of the students were aware of the indications for the use of SDF, only 56.8% of the general dentists reported it. Similarly, for hypersensitivity treatment, 71.1% of the students were informed versus 40.7% of the general dentists, and indications for paediatric patients, 100% for the DS group and 59.3% in GDPs. In adult patients, indications vary from GDPs' (50%) to DSs' (25.9%) responses. About 94.7% of DSs know the advantages of use and only 50.6% of GDPs. Both groups showed reluctance to use SDF in esthetic zones, with greater acceptance in non-esthetic areas (<i>p</i> < 0.05). In practice, fewer GDPs (27.16%) and DSs (23.68%) had applied SDF, reflecting a gap between knowledge and implementation. <b>Conclusions:</b> Dental students had a significantly higher level of knowledge, a situation that evidences the high level of education and training in the curricular guides of the universities.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11764097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Collagenated and Non-Collagenated Deproteinized Bovine Bone Mineral on Schneiderian Membrane Integrity in Rabbits.","authors":"Rihito Yamada, Samuel Porfirio Xavier, Yasushi Nakajima, Erick Ricardo Silva, Daniele Botticelli, Yuki Teranishi, Shunsuke Baba","doi":"10.3390/dj13010019","DOIUrl":"10.3390/dj13010019","url":null,"abstract":"<p><p><b>Background:</b> This investigation focused on the influence of collagen on the integrity of the Schneiderian membrane during maxillary sinus augmentation in a rabbit model. The aim of this study was to elucidate the relationship between membrane integrity and bone regeneration in augmented maxillary sinuses using collagenated and non-collagenated grafts, through detailed histological and histomorphometric analyses. <b>Methods:</b> In this forward-looking, randomized, split-mouth design, bilateral maxillary sinus augmentation was conducted on 12 rabbits. One sinus was filled with deproteinized bovine bone material (DBBM) as the grafting material (non-collagenated; control), while a combination of DBBM particles integrated with 10% porcine-derived type I collagen was used in the contralateral sinus (collagenated; test). Histological analyses were carried out following healing periods of 2 and 12 weeks. <b>Results:</b> At the 2-week time point, six sites of thinned mucosa (<40 µm) and no perforations were observed in the collagenated group, while twenty-one thinned mucosa sites (<i>p</i> = 0.027 between test and control) and two perforations (<i>p</i> = 0.175 between test and control) were found in the non-collagenated group. After 12 weeks of healing, the number of sites with thinned mucosa was 20 in the collagenated group and 19 in the non-collagenated group, with four perforations observed in each group. These perforations were distributed across three sinuses in the collagenated group and two sinuses in the non-collagenated group. No statistically significant differences were found between the groups. <b>Conclusions</b>: The addition of 10% collagen to deproteinized bovine bone mineral initially provided protection against mucosal thinning and perforation after 2 weeks of healing. However, by week 12, this protective effect diminished, resulting in similar rates of mucosal thinning and perforations in both groups.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143031929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Antimicrobial Photodynamic Therapy for Treating Moderate to Deep Periodontal Pockets in Individuals with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.","authors":"João Victor Soares Rodrigues, Mariella Boaretti Deroide, Wilton Mitsunari Takeshita, Valdir Gouveia Garcia, Rafael Scaf de Molon, Leticia Helena Theodoro","doi":"10.3390/dj13010021","DOIUrl":"10.3390/dj13010021","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Diabetes mellitus and periodontitis share a significant, bidirectional relationship. Diabetes raises the risk of periodontitis and influences its severity, impacting tissue repair and bone metabolism. Conversely, periodontal inflammation can disrupt glycemic control, further complicating this interlinked relationship. This systematic review aimed to evaluate the efficacy of antimicrobial photodynamic therapy (aPDT) as an adjunct to subgingival instrumentation (SI) in the treatment of periodontal pockets with a probing pocket depth (PPD) ≥ 5 mm in individuals with type 2 diabetes mellitus (DM2) and periodontitis. <b>Methods:</b> Using the PICOS framework, this review addressed the following question: \"How does aPDT as an adjunct to SI compare to SI alone in treating periodontal pockets with PPD ≥ 5 mm in individuals with DM2 and periodontitis?\" Databases searched included PubMed, Scopus, and Web of Science up to December 2024. Randomized clinical trials evaluating periodontal status and HbA1c levels in patients with DM2 undergoing periodontal therapy and experiencing SI were included. Patients who received adjunctive aPDT were compared to a control group that received SI alone. A meta-analysis was conducted illustrating treatment effects across groups. <b>Results:</b> After screening 117 studies based on titles and abstracts, three and four studies met the eligibility criteria for quantitative and qualitative analyses, respectively. The principal periodontal parameters assessed included PPD, clinical attachment level (CAL), plaque index (PI), and bleeding on probing (BOP). Forest plots for PD, BOP, PI, and CAL at baseline, three months, and six months revealed no statistically significant differences between the SI+aPDT group and the SI-only group. Glycated hemoglobin across treatment groups was not different. <b>Conclusions:</b> The combination of aPDT with SI provides limited clinical benefits in treating periodontal pockets with a PPD ≥ 5 mm in diabetic patients with periodontitis.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}