Adrian Jantea, Sorin Gheorghe Mihali, Dan Lolos, Anca Tudor, Roxana Oancea, Liliana Porojan
{"title":"Immediate Patient Satisfaction with Dental Esthetics After Endodontic and Prosthodontic Treatment of Dental Dyschromia.","authors":"Adrian Jantea, Sorin Gheorghe Mihali, Dan Lolos, Anca Tudor, Roxana Oancea, Liliana Porojan","doi":"10.3390/dj13010044","DOIUrl":"10.3390/dj13010044","url":null,"abstract":"<p><p><b>Objectives:</b> This study aimed to evaluate patients' satisfaction with the esthetic outcomes of combined endodontic and prosthetic treatments for devitalized or dyschromic teeth, a condition influenced by various intrinsic and extrinsic factors that present a growing concern in modern dentistry. <b>Methods:</b> A total of 104 patients, including 43 men and 61 women, underwent treatment using lithium disilicate restorations for esthetic zones and zirconium oxide restorations for regions with higher occlusal demands. Patient satisfaction was evaluated through a post-treatment questionnaire, classifying responses as either \"satisfied\" or \"dissatisfied\". Dissatisfied participants were further asked to specify their concerns. <b>Results:</b> The study revealed a high satisfaction rate of 93%. Dissatisfaction was slightly more prevalent among women than men, but this difference was statistically insignificant. The primary reasons for dissatisfaction included darker restoration color, chipping, and gingival recessions. <b>Conclusions:</b> Combined endodontic and prosthetic treatments, utilizing lithium disilicate and zirconium oxide restorations, achieved high levels of patient satisfaction. Nevertheless, addressing specific issues, such as color matching and gingival health, could enhance outcomes further.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11764403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143031926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alice Arina Ciocan Pendefunda, Cristina Gena Dascalu, Sebastian Bahrim, Cristina Iordache, Odette Luca, Magda-Ecaterina Antohe
{"title":"Practical Implications in Contemporary Dental Aesthetics-Shade Selection Assessment Using Intraoral Scanners.","authors":"Alice Arina Ciocan Pendefunda, Cristina Gena Dascalu, Sebastian Bahrim, Cristina Iordache, Odette Luca, Magda-Ecaterina Antohe","doi":"10.3390/dj13010043","DOIUrl":"10.3390/dj13010043","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Aesthetics is a challenging aspect to restore for both dentists and dental technicians. One of the characteristics of aesthetic restoration is the shade. The purpose of the study is to assess the accuracy of the shade selection feature of intraoral scanners (CEREC Omnican, 3Shape TRIOS) in comparison with an already established method-the VITA Easyshade V spectrophotometer (VE)-and test if there is any significant difference between the three devices. <b>Methods:</b> To conduct this in vitro study, the VITA Classical shade guide was used. The intraoral scanners would not be able to scan the VITA Classical as it is, hence, a study model (SM) was fabricated. To be able to test the accuracy of the intraoral scanners (IOSs) in detecting the dental color, a spectrophotometer had to be included in the study, as it was shown that it is the most accurate instrument for this purpose. Therefore, for the current study, the VITA Easyshade V spectrophotometer (VITA Zahnfabrik, Bad Sackingen, Germany) was selected. <b>Results:</b> The accuracy of the three devices when measuring the shade of the study model was calculated as a percentage. When comparing the primary results of the VE and the results obtained by the Omnicam and TRIOS, the latter is the most accurate (26.67%), whereas the other two scored 20%. The study also revealed the limitations of the instrumental devices that were used. <b>Conclusions:</b> First, both the VE and IOSs obtained unexpectedly low accuracy results. Possibly, the material VC is made of influenced the final accuracy values, but in practice, on a daily basis, dental materials represent a factor that cannot really be controlled.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Outcomes and Complication Rates of Endodontically Treated Teeth with Fixed Dental Prostheses: A Retrospective Study.","authors":"Sarah Aloqayli, Hanin Alsalhi, Ali Alenezi","doi":"10.3390/dj13010042","DOIUrl":"10.3390/dj13010042","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Endodontically treated teeth (ETT) often have significant structural damage and require multiple reinforcing methods during the reconstruction process. The aim of this study was to evaluate the complication rates of ETT with and without a post. <b>Methods</b>: The study investigated various clinical factors, including technical complications as well as biological complications. All patients who had previously received fixed dental prostheses (FDPs) were subjected to clinical and radiographical examinations during their follow-up visits. Clinical and radiographic assessments were performed to determine the cumulative survival rate, and life table survival analyses of FDPs in the presence of complications were performed. <b>Results</b>: A total of 287 ETT were evaluated in this study, in which 219 were placed in females and 68 in males, with an average follow-up time of 82.4 months. There were no significant differences between ETT with a post and ETT without a post regarding the complication rates. The complication rates of the FDPs without a post revealed a survival rate of 58% after 5 years, 44% after 10 years, and 29% after 15 years. On the other hand, the complication rates of the FDPs with a post revealed survival rates of 50%, 30%, and 21% after 5, 10, and 15 years, respectively. The Kaplan-Meier survival analysis showed no significant differences in the complication rates, regardless of the existing of the posts (<i>p</i> = 0.830). <b>Conclusions</b>: ETT restored with FDPs with or without a post can show similar complication rates in a long-term evaluation. Furthermore, the types of final restoration may not have an effect on the complication rate with ETT.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11764337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does the Type of Resin Luting Material Affect the Bonding of CAD/CAM Materials to Dentin?","authors":"Burcu Dikici, Elif Türkeş Başaran, Esra Can","doi":"10.3390/dj13010041","DOIUrl":"10.3390/dj13010041","url":null,"abstract":"<p><p><b>Background/Objectives:</b> This study aimed to investigate the microtensile bond strength (µTBS) of composite-based (Cerasmart), polymer-infiltrated (Vita Enamic), and feldspathic (Cerec) CAD/CAM blocks luted to dentin using a dual-cure resin cement (LinkForce), as well as micro-hybrid (G-aenial) and flowable composites (G-aenial Universal Flo), and evaluate the microhardness (HV) of luting materials through the CAD/CAM blocks. <b>Methods:</b> Cerasmart, Enamic, and Cerec were luted to dentin using three luting materials; LinkForce, G-aenial, and Universal Flo (n = 5). For HV, 117 disk-shaped specimens from LinkForce, G-aenial, and Universal Flo (n = 13) were polymerized through 3 mm thick CAD/CAM. Thirty-nine light-cured specimens without CAD/CAM were used as control. Following 24 h storage, the µTBS and HV were evaluated. Data were analyzed using the two-way ANOVA and post hoc Tukey tests (<i>p</i> < 0.05). <b>Results:</b> The µTBS to dentin and HV were significantly influenced by the type of luting material and CAD/CAM material. With all the CAD/CAM materials, LinkForce and Universal Flo exhibited a significantly similar µTBS to that of dentin (<i>p</i> > 0.05). Compared with the control group, all the HV values of the luting materials decreased significantly (<i>p</i> < 0.05). <b>Conclusions:</b> Heavily filled flowable composites exhibit a bonding effectiveness similar to that of dual-cure resin cements. All the luting materials showed similar HV when polymerized through the polymer-infiltrated CAD/CAM material.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Influence of Posterior Class II Composite Restoration Location and Techniques on Marginal Sealing.","authors":"Mishel Haddad, Diva Lugassy, Mohana Barhum, Tamar Brosh, Shlomo Matalon","doi":"10.3390/dj13010039","DOIUrl":"10.3390/dj13010039","url":null,"abstract":"<p><p><b>Background/Objectives</b>: The success of treatment and prevention for secondary caries hinges significantly on the techniques employed in Class II composite restoration. Additionally, the location of the restored tooth within the oral cavity has emerged as a potential factor determining the quality of the restoration. A comprehensive understanding of these interrelated variables is crucial for advancing the efficacy and durability of dental composite restorations. The aim of this study was to assess how various restoration techniques and the specific location of the tooth restoration in the oral cavity affect marginal sealing, verified by the gap created in the tooth-restoration interface. <b>Methods</b>: Sixty extracted human teeth that had been indicated for orthodontic extraction were collected and embedded into a custom-made holder that was located in one of the four quadrants of a laboratory phantom head. Class II resin composite restorations, using flowable and packable composites, were performed on all teeth using two techniques: Pre-cure and Co-cure. The aging of the restored teeth was conducted using cyclic loading and thermocycling. After aging, the teeth were examined under a scanning electron microscope to measure the gap within the tooth-composite interface. Kolmogorov-Smirnov tests were used to assess the data distribution. Unpaired <i>T</i>-tests were employed to compare the mean gaps between the Pre-cure and Co-cure techniques. Additionally, unpaired <i>T</i>-tests were utilized to compare the mean gaps between the mesial and distal parts of the teeth. The Kruskal-Wallis test was used to compare the mean gaps among the four quadrants. The statistical significance was set at <i>p</i> = 0.05. <b>Results</b>: No significant difference in the gaps between the Pre-cure and Co-cure techniques was found (<i>p</i> = 0.212). The tooth's location did not generally affect the restoration's gap interface (<i>p</i> = 0.136). <b>Conclusions</b>: Flowable composites aid in restoring the deep margins of Class II composite restoration. Thus, the potential for further microleakage is similar for both the Pre-cure and Co-cure restoration techniques. The marginal seal of Class II composite restorations is effective when using both Pre-cure and Co-cure techniques, and the restoration site within the oral cavity does not significantly influence the tooth-composite interface seal.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clear Aligner Treatment: Indications, Advantages, and Adverse Effects-A Systematic Review.","authors":"Clara Rasborg Hartogsohn, Liselotte Sonnesen","doi":"10.3390/dj13010040","DOIUrl":"10.3390/dj13010040","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Clear aligner treatment (CAT) has gained interest among clinicians as well as among patients. The aim of the present study was to systematically review the literature regarding current viewpoints on indications, contraindications, advantages, disadvantages, and adverse effects in CAT. <b>Methods</b>: A search was performed in the PubMed and Embase databases, yielding 18 studies eligible for inclusion. <b>Results</b>: Current indications for CAT are mild to moderate malocclusions. Severe malocclusions with impactions or severe craniofacial skeletal deviations are contraindications. The advantages were oral hygiene and oral health as the most common, and disadvantages of CAT have been noted by several studies, including CAT still being inferior to fixed appliance treatment (FAT) in all orthodontic movements. Adverse effects were potential health risks due to microplastics and a decrease in condyle bone volume. <b>Conclusions</b>: No firm conclusions can be drawn regarding indications for CAT except for mild to moderate malocclusion. Severe malocclusions with impactions or severe craniofacial skeletal deviations are considered contraindications. In more complex cases, CAT is still considered inferior to FAT, although CAT contains advantages. There are disadvantages in CAT which clinicians should consider when choosing a type of orthodontic appliance for treating specific malocclusions. Only a few adverse effects in CAT were presented by the included studies. More high-quality research is needed regarding indications and contraindications for CAT.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11764167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Green Dentistry: State of the Art and Possible Development Proposals.","authors":"Stefano Speroni, Elisabetta Polizzi","doi":"10.3390/dj13010038","DOIUrl":"10.3390/dj13010038","url":null,"abstract":"<p><p><b>Objectives</b>: The objective of this narrative literature review was to highlight all dental procedures attributable to sectoral waste and to consider possible alternatives in line with the concept of sustainable development. <b>Methods</b>: An extensive search of electronic databases, including the Cochrane Oral Health Group Specialized Register, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, PubMed, EMBASE, and Google Scholar. Search words included 'Green Dentistry', 'Dental Pollution', 'Pollutants and Dentistry', 'Disinfectants and Dentistry', and 'High-tech Dentistry'. All of them allowed an assessment of the impact of dental practice on the external environment, and new frontiers currently applied or possibly applicable for green dentistry were included in the study. Non-full-text papers, animal studies, studies in languages other than English, and studies not related to the topic under consideration were excluded. <b>Results</b>: According to the inclusion criteria, 76 papers were selected for the study. The topics analyzed were the impact of dental practice on the outdoor environment, currently applied and potentially applicable principles of green dentistry, and the 'Four Rs' model (Rethink, Reduce, Reuse, and Recycle). <b>Conclusions</b>: With the limitations of the present study, the concept of green dentistry could be applicable provided that the measures already taken to reduce indoor and outdoor risk factors are continued and improved.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11764173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relationship Between the Salivary Microbiome and Oral Malodor Metabolites in Older Thai Individuals with Periodontitis and the Cytotoxic Effects of Malodor Compounds on Human Oral Squamous Carcinoma (HSC-4) Cells.","authors":"Witsanu Srila, Kritsana Sripilai, Thunwa Binlateh, Peungchaleoy Thammanichanon, Watcharaphol Tiskratok, Parinya Noisa, Paiboon Jitprasertwong","doi":"10.3390/dj13010036","DOIUrl":"10.3390/dj13010036","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Halitosis is primarily caused by the activity of oral microorganisms. In this study, we employed metagenomic sequencing and metabolomic approaches to investigate the differences in salivary microbiota and metabolite profiles between individuals with halitosis and periodontitis and healthy controls. Additionally, we expanded the study to examine how oral malodorous compounds interact with human oral squamous carcinoma (HSC-4) cells. <b>Methods</b>: Saliva samples were collected and analyzed using Ultra-High Performance Liquid Chromatography-Mass Spectrometry (UHPLC-MS) to identify metabolites. We then assessed the correlations between the microbiota and metabolites. Furthermore, the impact of oral malodorous substances on HSC-4 cells was investigated by evaluating apoptosis, antioxidant activity, and inflammatory properties. <b>Results:</b> The microbiota and metabolite profiles showed significant differences between the halitosis with periodontitis group and the periodontally healthy group. The halitosis with periodontitis group exhibited significantly higher relative abundances of eight genera: <i>Tannerella</i>, <i>Selenomonas</i>, <i>Bacteroides</i>, <i>Filifactor</i>, <i>Phocaeicola</i>, <i>Fretibacterium</i>, <i>Eubacterium saphenum</i>, and <i>Desulfobulbus</i>. In contrast, the periodontally healthy group showed significantly higher relative abundances of Family <i>XIII UCG-001</i>, <i>Haemophilus</i>, and <i>Streptobacillus</i>. Two metabolites, 2,3-dihydro-1H-indole and 10,11-dihydro-12R-hydroxy-leukotriene E4, were significantly higher in individuals with halitosis and periodontitis. In the treatment of HSC-4 cells with metabolites, dimethyl sulfide (DMS) did not show significant effects while indole appeared to induce cell death in HSC-4 cells by triggering apoptotic pathways. Additionally, both indole and DMS affected the inflammatory and antioxidant properties of HSC-4 cells. <b>Conclusions</b>: This study provides insights into the mechanisms of halitosis by exploring the correlations between microbiota and metabolite profiles. Furthermore, oral metabolites were shown to impact the cellular response of HSC-4 cells.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11764442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olivia Lili Zhang, Iris Xiaoxue Yin, Ollie Yiru Yu, Kenneth Luk, John Yun Niu, Chun Hung Chu
{"title":"Advanced Lasers and Their Applications in Dentistry.","authors":"Olivia Lili Zhang, Iris Xiaoxue Yin, Ollie Yiru Yu, Kenneth Luk, John Yun Niu, Chun Hung Chu","doi":"10.3390/dj13010037","DOIUrl":"10.3390/dj13010037","url":null,"abstract":"<p><p>The development of laser technology has revolutionized dentistry, offering complementary and alternative approaches to traditional techniques. Lasers have been successfully integrated into various dental procedures, enhancing treatment outcomes and patient care. Several types of lasers can increase the acid resistance of enamel, thus preventing caries. Laser fluorescence has been utilized for the pre-operative diagnosis of dental caries, enabling early detection and effective treatment planning. The therapeutic application of lasers in caries treatment aligns with the contemporary philosophy of minimally invasive procedures. Clinicians can use laser Doppler flowmetry as a supplementary tool for pulp vitality testing by detecting pulpal blood flow. Lasers are also employed in various pulp-related interventions, such as managing dentine hypersensitivity and performing root canal therapy. These procedures benefit from the precision and reduced invasiveness provided by laser technology. Furthermore, laser fluorescence serves as an additional tool for subgingival calculus detection. High-power and low-power lasers are used in both nonsurgical and surgical therapies to treat periodontal and peri-implant diseases, oral mucosa conditions, and even cancer based on their specific properties. Lasers are also utilized to accelerate bone regeneration, promote adhesive strength, and remove ceramic brackets. In summary, laser technology has significantly impacted contemporary dentistry by facilitating early diagnosis, minimally invasive treatments, and precise operative procedures, ultimately improving patient outcomes and expanding the scope of dental practice.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multiple Sessions of Antimicrobial Photodynamic Therapy Improve Periodontal Outcomes in Patients with Down Syndrome: A 12-Month Randomized Clinical Trial.","authors":"Rafael Ferreira, Sebastião Luiz Aguiar Greghi, Adriana Campos Passanezi Sant'Ana, Mariana Schutzer Ragghianti Zangrando, Carla Andreotti Damante","doi":"10.3390/dj13010033","DOIUrl":"10.3390/dj13010033","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Individuals with Down syndrome (DS) often present with severe periodontal disease at a young age. Adjuvant treatments to scaling and root planing (SRP), such as antimicrobial photodynamic therapy (aPDT), may benefit this population. This study evaluated the effectiveness of aPDT as an adjunct to SRP in individuals with DS. A randomized, double-blind, parallel trial was conducted with 37 individuals with DS. <b>Methods:</b> The test group (aPDT; <i>n</i> = 18) received SRP + aPDT, while the control group (C group; <i>n</i> = 19) received SRP only. For aPDT, a red laser (658 nm; 0.1 W; 2229 J/cm<sup>2</sup>; 40 s sweeping with optical fiber) combined with methylene blue (MB) (100 µg/mL) was applied across repeated sessions (on days 3, 7, and 14). Clinical parameters, such as plaque index (PI), clinical attachment level (CAL), probing depth (PD), and bleeding on probing (BOP), were recorded at baseline and after 3, 6, and 12 months of treatment. Statistical analyses were performed using parametric and non-parametric tests (<i>p</i> < 0.05). <b>Results:</b> Both treatments promoted improvements in all clinical periodontal parameters (<i>p</i> < 0.05). The aPDT group showed a statistically significant reduction in CAL at 3 months (aPDT = 4.58 mm vs. C = 4.72 mm; <i>p</i> < 0.05) and 12 months (aPDT = 4.59 mm vs. C = 4.84 mm; <i>p</i> < 0.05). <b>Conclusions:</b> aPDT improved periodontal health in the long term through a stable gain in attachment.</p>","PeriodicalId":11269,"journal":{"name":"Dentistry Journal","volume":"13 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}