Developmental psychobiology最新文献

{"title":"Probing Puberty as a Source of Developmental Change in Neural Response to Emotional Faces in Early Adolescence","authors":"M. Morningstar,&nbsp;J. A. Burns","doi":"10.1002/dev.70037","DOIUrl":"10.1002/dev.70037","url":null,"abstract":"<p>Pubertal development is theorized to shape the brain's response to socio-emotional information in the environment. Large-scale longitudinal studies, such as the Adolescent Brain Cognitive Development (ABCD) study, provide the opportunity to examine the association between pubertal maturation and within-person changes in neural activation to emotional stimuli over time. Leveraging ABCD data (<i>n </i>= 9648), the current study examines the coupling between parent-reported pubertal development and changes in youth's brain response to emotional faces in an emotional <i>n</i>-back task (during functional magnetic resonance imaging) across two timepoints (2 years apart). Bivariate latent change score models were fit to regions of interest canonically involved in face processing (fusiform), emotional/motivational salience (amygdala, nucleus accumbens, orbitofrontal cortex [OFC]), and social cognition (temporoparietal junction [TPJ]) to determine the associations between baseline pubertal status and neural response, and rate of change in either variable across time. Results point to both concurrent and longitudinal associations between pubertal maturation and neural activation to emotional faces in regions involved in processing emotional and social information (amygdala, TPJ, accumbens, OFC) but not basic facial processing (fusiform). These findings highlight pubertal maturation as a potential mechanism for change in neural response to emotional information during the transition from childhood to adolescence.</p>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"67 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70037","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lifetime Stressor Severity and Diurnal Cortisol in Older African American Adults: A Comparison of Three Theoretical Models","authors":"Katherine Knauft,&nbsp;Kristin M. Davis,&nbsp;Yanping Jiang,&nbsp;Grant S. Shields,&nbsp;Nataria Joseph,&nbsp;George M. Slavich,&nbsp;Samuele Zilioli","doi":"10.1002/dev.70034","DOIUrl":"10.1002/dev.70034","url":null,"abstract":"<p>Multiple theoretical models have been proposed to explain how stressor exposure across the life course relates to the functioning of the hypothalamic-pituitary-adrenal (HPA) axis, as indexed by daily cortisol secretion. However, this association remains understudied in African Americans. The present study tested three competing models of stressor severity across the lifespan and diurnal cortisol secretion in a sample of 203 older African American adults. The cumulative model emphasizes total stressor severity across the lifespan, the biological embedding model emphasizes early-life stressor severity, and the sensitization model instead emphasizes the interaction between early-life and recent stressor severity. Lifetime stressor severity was assessed using the Stress and Adversity Inventory for Adults (Adult STRAIN). Analyses did not support any of the three models tested but, rather, a stressor characteristics perspective, wherein the severity of exposure to specific stressor characteristics was associated with blunted diurnal cortisol slopes. Sensitivity analyses revealed that early life stressor count, rather than severity, was associated with blunted diurnal cortisol slopes. Rather than supporting one of the three competing models of stressor severity, our findings provide preliminary evidence for a stressor characteristics approach and the biological embedding model when examining how lifetime stressor exposure affects HPA-axis activity.</p>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"67 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obituary for Celia L. Moore (1942–2025)","authors":"George F. Michel","doi":"10.1002/dev.70039","DOIUrl":"https://doi.org/10.1002/dev.70039","url":null,"abstract":"","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"67 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing the Study of Maternal Prenatal Stress Phenotypes and Infant Temperament Outcomes","authors":"Christie Pham,&nbsp;Jennifer A. Mattera,&nbsp;Sara F. Waters,&nbsp;Erica J. Crespi,&nbsp;J. A. Madigan,&nbsp;SuYeon Lee,&nbsp;Maria A. Gartstein","doi":"10.1002/dev.70035","DOIUrl":"https://doi.org/10.1002/dev.70035","url":null,"abstract":"<p>Exposure to the in utero environment provides offspring risk or protection with respect to postpartum development and health across the lifespan. We used latent profile analysis (LPA), considering self-report and physiological indicators to assess the influence of maternal prenatal stress/distress on infant temperament. We predicted that participants who reported greater prenatal stress/distress would have infants with less optimal temperament characteristics (e.g., higher fearfulness, lower smiling/laughter). Women (<i>N</i> = 67) were recruited in the Southwest Washington and Eastern Washington/North Idaho areas. Participants responded to surveys during the third trimester and provided hair samples for cortisol analyses. Postpartum mothers reported on infant temperament. LPA resolved two statistically supported profiles, reflecting lower and higher maternal stress/distress during pregnancy, which we compared with respect to infant temperament (e.g., fearfulness, smiling/laughter). The greater stress/distress exposure group demonstrated higher cortisol concentrations, depression, general anxiety, and perceived stress. Mothers with greater prenatal stress/distress profiles reported their children exhibiting more challenging temperaments (e.g., higher negative emotionality). This pattern of results suggests that groups discernable in terms of prenatal stress/distress exposure also differ with respect to infant reactivity and regulation.</p>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"67 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental Enrichment Has Age- and Sex-Specific Effects on Fear Regulation in Mice","authors":"Hannah G. Burnell,&nbsp;Beckett R. J. Blocker,&nbsp;Heidi C. Meyer","doi":"10.1002/dev.70038","DOIUrl":"https://doi.org/10.1002/dev.70038","url":null,"abstract":"<div>\u0000 \u0000 <p>Previous research has sought to understand the mechanisms by which early life adversity disrupts later behavioral function. Yet less has been done to investigate the effects of positive experiences such as environmental enrichment. Here, we examined the effects of brief (2 weeks) or extended (8 weeks) environmental enrichment on discrimination, fear inhibition, and fear extinction during adolescence or adulthood. Two conditions of enrichment were used: a “Hut” group received a polycarbonate Hut in the home cage throughout the duration of the experiment, while a “Variable” group received a polycarbonate Hut, as well as a series of rotating enrichment features. Our data show that in females, brief Variable enrichment increased the rate of learning about cues that explicitly indicate safety during adolescence while disrupting this type of learning in adults. In males, enrichment did not influence learning about safety cues. Conversely, in males, brief Variable enrichment initially improved extinction, but extended enrichment (Variable or Hut) was necessary to see sustained improvements across extinction. This pattern was apparent for both adolescents and adults. In females, Variable enrichment did not affect extinction, while Hut enrichment increased freezing for all mice initially and adolescents as extinction continued. This work has the potential to inform treatments and interventions for fear-related disorders, such as anxiety and post-traumatic stress disorder, tailored for both specific developmental ages and sex.</p>\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"67 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Properties of the Neural Response to Rewards and Errors Across Mid- to Late-Adolescence","authors":"A. K. Szenczy,&nbsp;A. Sabharwal,&nbsp;A. R. Levinson,&nbsp;Z. P. Infantolino,&nbsp;G. Perlman,&nbsp;R. Kotov,&nbsp;D. N. Klein,&nbsp;B. D. Nelson","doi":"10.1002/dev.70036","DOIUrl":"https://doi.org/10.1002/dev.70036","url":null,"abstract":"<div>\u0000 \u0000 <p>Event-related potential (ERP) measures of reward- and error-related brain activity have been used to elucidate neural mechanisms contributing to the development of psychopathology. Adolescence is a critical developmental period that is associated with changes in ERP reward- and error-related brain activity. However, there is a paucity of within-subject research examining whether the reliability of ERP measures is the same or changes across adolescence. Moreover, it is unclear whether the time-frequency representation of reward- and error-related brain activity demonstrates similar psychometric properties. The present study examined the psychometric properties of reward- and error-related brain activity in five hundred and fifty 13.5- to 15.5-year-old (<i>M</i> = 14.4, SD = 0.63) girls. Participants completed the doors and flanker tasks while electroencephalography (EEG) was recorded at two assessments: baseline and 3 years later. Reward- and error-related brain activity were quantified using the time-domain reward positivity (RewP) and error-related negativity (ERN), respectively, as well as time-frequency delta and theta activity. Results indicated that all measures demonstrated adequate split-half reliability at each assessment and 3-year test–retest reliability across assessments. The present study indicates that the psychometric properties of time-domain and time-frequency reward- and error-related brain activity are largely consistent across adolescence, supporting their potential use as individual differences measures of risk for psychopathology.</p>\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"67 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do Expectant Mothers Exhibit Different Autonomic Responses to the Infant Cry Stimuli at Home Versus in the Laboratory?","authors":"Shane Denherder,&nbsp;Dylan Neff,&nbsp;Bailey Speck,&nbsp;Joshua Marchant,&nbsp;Rose McLaughlin,&nbsp;K. Lee Raby,&nbsp;Sheila E. Crowell,&nbsp;Elisabeth Conradt","doi":"10.1002/dev.70032","DOIUrl":"https://doi.org/10.1002/dev.70032","url":null,"abstract":"<p>The COVID-19 pandemic introduced challenges for keeping participants and research assistants safe during laboratory visits. One solution was administering research assessments in the participant's home via an online platform, despite limited evidence of whether online tasks have similar effects as laboratory contexts. The present study compares physiological responses to a virtual adaptation of an infant cry stimulus—which is commonly used to evoke and measure autonomic nervous system responses among pregnant individuals—to a traditional laboratory-based cry task. Respiratory sinus arrhythmia (RSA), electrodermal activity (EDA), and heart rate (HR) were collected during infant cry presentation from 120 pregnant women in their third trimester. Half of the participants observed the infant cry stimulus in the laboratory before the pandemic, and the other half had the task delivered remotely using online teleconferencing technology in their homes. Results revealed that EDA increased and RSA decreased in response to the infant cry stimulus. HR did not significantly change from baseline to the infant cry stimulus. Importantly, whether the participants watched the infant cry stimulus at home versus in the laboratory did not affect their autonomic responses to the stimulus. These results demonstrate the ability of remote tasks to elicit an attachment-relevant stress response in pregnant women for remote data collection.</p>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"67 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143581429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-Changes and Mutual Influences of Fearful Temperament, Task Switching, and Maternal Intrusiveness in Early Childhood","authors":"Ran Liu,&nbsp;Cynthia L. Smith,&nbsp;Martha Ann Bell","doi":"10.1002/dev.70031","DOIUrl":"https://doi.org/10.1002/dev.70031","url":null,"abstract":"<div>\u0000 \u0000 <p>This study employed latent change score models to examine the co-changes and mutual influences of fearful temperament, task switching, and maternal intrusiveness in early childhood. Participants included 335 children (171 boys, 164 girls; <i>M</i>_age = 3.09 years at baseline; 77.3% White, 14.0% Black, 8.4% multiracial, 0.3% Asian, 7.8% Hispanic) and their mothers. Higher levels of maternal intrusiveness at 36 months predicted a smaller increase in children's task switching between 36 and 48 months. Higher levels of task switching at 36 months predicted a larger decrease in fearful temperament. The changes between task switching and fearful temperament co-occurred; as the degree of task switching increased, fearful temperament decreased, or vice versa. Family-oriented interventions that reduce maternal intrusiveness may facilitate children's improvements in task switching, which is closely associated with the development of a fearful temperament.</p>\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"67 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143582024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Attachment Disruption Increases Central Sensitivity of Depressive-Like Behavior to Stimulation by PGE-2","authors":"Michael B. Hennessy,&nbsp;Olivia Slomski,&nbsp;Joel L. Spenny,&nbsp;Tisha R. Sharma,&nbsp;Patricia A. Schiml,&nbsp;Terrence Deak","doi":"10.1002/dev.70033","DOIUrl":"https://doi.org/10.1002/dev.70033","url":null,"abstract":"<div>\u0000 \u0000 <p>Early disruption of filial attachment appears to sensitize underlying threat-related processes to produce vulnerability for developing depression when encountering stressors later in life. Evidence indicates neuroinflammatory signaling mediates this effect, though exact mechanisms are poorly understood. In a guinea pig model, early periods of isolation from the mother produce depressive-like behavior and fever, which sensitize with repeated isolation. Because cyclooxygenase inhibitors reduce these effects, the sensitization appears to involve prostaglandins such as PGE-2. We asked if isolation increased central sensitivity to PGE-2, which could underlie the sensitization process. Experiment 1 established that intraventricular (ICV) infusion of 1 or 3 µg of PGE-2 increased depressive-like behavior in pups. The 3 µg dose also produced an initial suppression and then a rise in core temperature. In Experiment 2, repeated isolation of pups sensitized depressive-like behavior. Days later (early adolescence), 1 µg of ICV-PGE-2 increased depressive-like behavior in previously isolated guinea pigs, but not in non-previously isolated controls. Core temperature was unaffected. Thus, early isolation from the mother increased sensitivity of depressive-like behavior, but not fever, to PGE-2. Results suggest that increased sensitivity to PGE-2 could play a role in the enhanced vulnerability to depression in adolescents previously exposed to early attachment disruption.</p>\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"67 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143581430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Serotonergic Control of Play Fighting in Male Juvenile Hamsters: Opposite Effects of 5-HT1A and 5-HT3 Receptor Manipulations","authors":"Candice L. Malone,&nbsp;Lina Fernanda González-Martínez,&nbsp;Gabrielle E. J. Gray,&nbsp;Kevin M. Moran,&nbsp;Kereshmeh Taravosh-Lahn,&nbsp;Yvon Delville","doi":"10.1002/dev.70030","DOIUrl":"https://doi.org/10.1002/dev.70030","url":null,"abstract":"<div>\u0000 \u0000 <p>In male hamsters, puberty is associated with increased serotonin innervation and unusual responses to fluoxetine, such as enhanced play-fighting activity against intruders but also an acceleration of its maturation from attacks focused on the face (frontal attacks) to the lower belly and rump, suggesting a role for serotonin (5-HT). We tested the role of 5-HT_1A and 5-HT₃ receptor subtypes on play-fighting behavior observed during resident intruder tests through peripheral treatment with receptor agonists and antagonists. Contrary to observations in adult hamsters, we did not observe any overarching effects of treatment on measures of play-fighting activity, nor its maturation from frontal attacks. However, secondary analyses highlighted variability within the datasets. A subgroup of animals presented inhibited play-fighting activity in response to treatment with DPAT, a 5-HT_1A receptor agonist, but these animals also showed enhanced locomotor activity and reduced interest in engaging their opponents. In addition, early juvenile agonistic behavior was predictive of responsiveness to other treatments. The 5-HT_1A receptor antagonist, WAY, caused a reduction in play-fighting activity in high attackers and an increase in low attackers. Though high attackers under pretest conditions were equally inhibited by CBG, a 5-HT₃ receptor agonist, they performed a higher proportion of frontal attacks. Finally, the density of 5-HT_1A and 5-HT₃ receptor immunoreactivity was compared among subjects sampled at postnatal Day 35 (early puberty) or postnatal Day 70 (adulthood) within areas mediating the control of social behavior in adults. Adult males showed a higher density of immunolabeling for 5-HT_1A receptors in the anterior hypothalamus and medial amygdala, as well as 5-HT₃ receptors in the lateral septum. The data suggest that the development of 5-HT receptor expression participates in the control of play-fighting activity and its maturation during puberty in male hamsters.</p>\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"67 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143489939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}