Developmental psychobiology最新文献

{"title":"Early Childhood Emotional, Relational, and Stress-Related Outcomes Following Infant Cardiac Surgery","authors":"Tamera A. Clancy,&nbsp;Carolina de Weerth,&nbsp;Frank Muscara,&nbsp;Brigid Jordan","doi":"10.1002/dev.70200","DOIUrl":"10.1002/dev.70200","url":null,"abstract":"<p>Children with congenital heart disease (CHD) experience significant early-life stress through medical interventions and hospitalization, shaping physiological and psychological development. This study examined emotional and behavioral regulation and salivary cortisol responses in preschool-aged children who underwent cardiac surgery in infancy, and explored the parent–child relationship as a source of co-regulation and buffering support. In this prospective cohort, 22 preschoolers with CHD and their parents participated in a hospital-based laboratory visit. Child salivary cortisol was collected at three time points. Observed parent–child interactions were coded using the Emotional Availability Scales, and parent-reported Child Behavior Checklist (CBCL) scores assessed emotional and behavioral regulation. Mixed-effects models examined associations between cortisol response, CBCL scores, and relationship quality. Significant individual variability in cortisol response was observed. Lower cortisol levels were associated with greater emotional and behavioral difficulties and higher parent-reported traumatic stress at the time of their child's surgery. Longer hospital stays predicted blunted cortisol responses. Children in lower quality relationships displayed flatter cortisol profiles. Findings highlight the impact of early medical stress on stress physiology and suggest emotionally available relationships may buffer HPA axis dysregulation. Results identify potential intervention targets to support psychosocial development and parent–child relationships and contribute to the emerging use of stress biomarkers in CHD research.</p>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13575582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148966982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CUD-PRS: Predicting Cannabis Use and Neurostructural Impacts in Adolescents.","authors":"Wenjin Xu, Wenhua Zhou, Xiaohu Xie","doi":"10.1002/dev.70206","DOIUrl":"https://doi.org/10.1002/dev.70206","url":null,"abstract":"<p><p>With recreational cannabis use rising globally, understanding and preventing cannabis use disorders (CUD) has become increasingly important. Cupertino et al.'s recent study (2025) sheds light on the development mechanism of CUD. Our commentary briefly highlights their key findings and the clinical significance of their work: genetic vulnerability influences early cannabis use, and adolescence is a crucial period when this risk is most likely to emerge. We believe their work suggests that identifying individuals with high genetic risk early on could help shape targeted prevention strategies. Notably, white matter integrity and impulsive behavior appear to mediate the link between genetic risk and cannabis use. Based on this, we propose screening of adolescents for genetic susceptibility or white matter abnormalities in the future, followed by targeted behavioral, cognitive, or neuromodulation interventions to strengthen white matter integrity and potentially reduce the risk of CUD development.</p>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 5","pages":"e70206"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149029885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screen-Time Neuroimaging Requires Context Beyond Exposure Minutes: A Taiwan Perspective.","authors":"Ting-Yuan Huang, Lien-Chung Wei","doi":"10.1002/dev.70204","DOIUrl":"https://doi.org/10.1002/dev.70204","url":null,"abstract":"","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 5","pages":"e70204"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149029918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Disruption in the NICU: When Natural Sleep Behavior Looks Like Distress","authors":"Jeroen Dudink,&nbsp;Greta Sokoloff,&nbsp;Richard Bartels,&nbsp;Tessa de Haan,&nbsp;Mark S. Blumberg","doi":"10.1002/dev.70197","DOIUrl":"10.1002/dev.70197","url":null,"abstract":"&lt;p&gt;A newborn rat lies quietly on its side, eyes sealed and body still. Suddenly, it twitches—its four limbs, tail, and whiskers moving in brief bursts that recur throughout the day and night. No contemporary sleep scientist would regard these movements as pathological. Instead, twitches are defining features of active, or rapid eye movement (REM), sleep and are increasingly recognized as playing important roles in sensorimotor development (Blumberg et al. &lt;span&gt;2022&lt;/span&gt;).&lt;/p&gt;&lt;p&gt;However, in premature human infants in the neonatal intensive care unit (NICU), similar movements often provoke concern. The contrast between how sleep scientists and clinicians interpret twitches reflects a persistent misalignment between basic and clinical science that may have practical implications for bedside interpretation of infant behavior. For example, twitching during sleep is sometimes confused with seizures, a situation familiar to many neonatal caregivers. Also, when sleep-state context is not explicitly incorporated into assessment, healthcare professionals can misclassify the facial and limb twitches of active sleep as indicators of distress. Indeed, commonly used pain and agitation scales explicitly score these movements as signs of discomfort. In response, caregivers may interrupt sleep and even initiate interventions intended to relieve the perceived distress. Although well intentioned, such interventions can alter and even suppress normal sleep.&lt;/p&gt;&lt;p&gt;The recognition of sleep-related movements as normal infant behavior dates back nearly a century. In the 1950s, Aserinsky and Kleitman (&lt;span&gt;1955&lt;/span&gt;) identified active sleep and its accompanying motility cycles in infants, establishing a foundation for modern sleep science. In 1966, Roffwarg et al. (&lt;span&gt;1966&lt;/span&gt;) proposed the ontogenetic hypothesis of active sleep, positing that the high prevalence of that sleep state in early life promotes endogenous stimulation of the developing brain. Subsequent work showed that brainstem activity generates the phasic motor events characteristic of active sleep, including rapid eye movements and twitches of the limbs and face. In human preterm and full-term infants, twitches occur many thousands of times each day across the body, including the face (Figure 1A; Sokoloff et al. &lt;span&gt;2026&lt;/span&gt;).&lt;/p&gt;&lt;p&gt;Evidence accumulated over recent decades indicates that sleep-related twitching likely benefits, rather than burdens, the developing nervous system. Studies in neonatal rodents and human infants demonstrate that twitches are structured outputs of brainstem motor networks rather than random by-products of dreaming (Blumberg et al. &lt;span&gt;2022&lt;/span&gt;; Sokoloff et al. &lt;span&gt;2026&lt;/span&gt;). Their discrete, single-joint character distinguishes them from the more complex, multi-joint movements of wakefulness. Each twitch produces sensory feedback that propagates through the spinal cord, cerebellum, thalamus, cortex, and hippocampus. Together with internal copies of moto","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13530305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148863952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Profiles of Anxiety in Children Undergoing Elective Surgery: Predictors and Perioperative Outcomes","authors":"Kristie L. Poole,&nbsp;Cheryl H. T. Chow,&nbsp;Norman Buckley,&nbsp;Desigen Reddy,&nbsp;Ryan J. Van Lieshout,&nbsp;Louis A. Schmidt","doi":"10.1002/dev.70196","DOIUrl":"10.1002/dev.70196","url":null,"abstract":"<p>Surgery is an anxiety-provoking event, but there are individual differences in the magnitude of experienced anxiety. The objective of this study was to identify patterns of children's preoperative anxiety, its predictors, and perioperative outcomes. The sample included 171 children (<i>M</i>_age = 9.95 years) undergoing elective surgery. We derived groups of children's anxiety based on multiple indicators (i.e., self-report, heart rate, and frontal brain EEG activity) during a preoperative visit and on the day of surgery. Parents and children reported on children's temperament, children's behavior was coded in the operating room, and postoperative pain ratings were collected. Two latent profiles of children were identified, including a subset with relatively average anxious responses across indicators (74%) and a subset with relatively heightened anxious responses across indicators (26%). Children in the heightened anxiety subgroup had higher levels of temperamental shyness, displayed greater observed distress behaviors (e.g., resistance to anesthesia, screaming) upon operating room entry, and tended to have higher levels of postoperative pain compared to children in the average anxiety subgroup. These results reveal child-level predictors and perioperative outcomes associated with the experience of elevated anxiety in the surgical context.</p>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13529925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148863920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variation in Everyday Maternal Sensitivity Predicts Infants’ Real-Time Physiological Regulation","authors":"Anna Madden-Rusnak,&nbsp;Megan Micheletti,&nbsp;Taylor Wilds,&nbsp;Kaya de Barbaro","doi":"10.1002/dev.70193","DOIUrl":"10.1002/dev.70193","url":null,"abstract":"<p>While maternal sensitivity is generally considered a stable trait, recent work has found that caregiver sensitivity varies substantially across the day as caregivers respond to their infants amid everyday demands and distractions. It remains unknown how variation in everyday caregiver sensitivity influences infants’ real-time physiological regulation during naturally occurring distress. In a sample of 23 infants (1–10 months old, 48% female), we synchronized infant-worn full-day home audio recordings and heart rate monitors to examine changes in infants’ respiratory sinus arrhythmia (RSA) following the onset of spontaneous distress, that is, episodes of fussing or crying, occurring across the day (<i>N</i> = 332 episodes, <i>M</i> = 14.34 per dyad). Caregiver sensitivity was coded individually for each episode of infant distress on a 1–7 scale, and RSA was time-locked to distress onset. Between-person analyses found that infants of caregivers with above-average sensitivity (i.e., sensitivity greater than the sample mean) showed adaptive decreases in RSA following distress onset. Additionally, within-person analyses found that infants also displayed significant decreases in RSA only on occasions when caregivers responded more sensitively relative to their <i>own</i> average. These findings demonstrate that both stable differences in caregiving quality and moment-to-moment variation in sensitivity shape infant's physiological regulation during everyday distress interactions.</p>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70193","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Empirical Evidence for the Developmental Origins of Autonomic Stress Regulation: An Attachment Account","authors":"Stefania V. Vacaru,&nbsp;Victoria L. Zhu,&nbsp;Greeshma Giridas,&nbsp;Lukas Spiess,&nbsp;Aicha Mazrina,&nbsp;Theodore E. A. Waters","doi":"10.1002/dev.70195","DOIUrl":"10.1002/dev.70195","url":null,"abstract":"<p>The quality of the developmental context is proposed to calibrate lifelong stress regulation. Integrating attachment theory with the adaptive calibration model, we tested whether adults exhibit distinct autonomic stress profiles and whether profile membership is associated with attachment security. Adults (<i>N</i> = 110; 57% female; <i>M</i>_Age = 20.46 years) completed the attachment script assessment (ASA) while heart rate variability (HRV) and skin conductance level (SCL) were continuously recorded as indices of parasympathetic and sympathetic activity. Latent profile analysis (LPA) and K-Means clustering were employed to identify autonomic profiles, and multinomial models were used to test ASA as a predictor of profile membership. Three profiles emerged from the interaction between HRV and SCL activation. In multinomial models with the buffered profile as reference, higher attachment security was associated with lower odds of the unemotional profile across both LPA and <i>K</i>-Means (OR = 0.49 and OR = 0.45), whereas the sensitive and buffered profiles did not differ. An exploratory interaction with sex emerged in the latent profile solution, with females showing higher ASA scores than males within the sensitive profile. Findings support the hypothesis that autonomic stress profiles are linked to attachment security, with lower secure base script knowledge associated with the more dysregulated unemotional profile.</p>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70195","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developmental Changes in Nest Egression Behavior and Its Relation to Novel Food Availability","authors":"Bridget L. McNally,&nbsp;Isabella B. Allar,&nbsp;Danny Lazega,&nbsp;James Liu,&nbsp;Donald C. Collins,&nbsp;Joost X. Maier","doi":"10.1002/dev.70194","DOIUrl":"10.1002/dev.70194","url":null,"abstract":"<div>\u0000 \u0000 <p>Nest egression constitutes a major developmental milestone for rats toward independence and is thought to be motivated in part by the need to acquire novel sources of nutrition when milk supply and nursing frequency decline. Here, we tested the hypothesis that nest egression is facilitated by the presence of food outside of the home cage. Spatial location of rat pups was tracked throughout a large environment where they were free to explore away from the home cage through tunnels that gave access to satellite cages. The availability of novel foods in satellite cages was systematically varied on a daily basis. Pup movement was continuously tracked via permanently implanted radio-frequency ID tags. The results show that nest egression first occurred at P12 and increased in spatial extent until P16; at P16, locomotion patterns underwent an abrupt shift toward a mature pattern. The emergence of mature locomotion patterns preceded the onset of food consumption, which was first evident on P17. Preference for locations containing foods emerged only after the onset of consumption; prior to P18, rats avoided locations containing foods. These findings suggest that the emergence of nest egression is not motivated by sensory cues associated with foods and provide insight into the processes that enable independent feeding.</p>\u0000 </div>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148826005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Linking Brain, Heart, and Behavior in Children: Frontal Electroencephalogram Activity, Respiratory Sinus Arrhythmia, and Internalizing Behaviors","authors":"Youre Yang,&nbsp;Kristie L. Poole,&nbsp;Louis A. Schmidt","doi":"10.1002/dev.70192","DOIUrl":"10.1002/dev.70192","url":null,"abstract":"<p>Internalizing behaviors are characterized by inward-focused emotional distress, which often manifests as symptoms such as depression, anxiety, and negative affect. Previous research has found that physiological correlates of heightened emotional arousal, such as phasic changes in overall frontal electroencephalogram (EEG) alpha activity (FAA) and respiratory sinus arrhythmia (RSA), are independently associated with emotion dysregulation and internalizing behaviors in children. The present study examined whether the interaction of changes in overall FAA and changes in RSA from baseline to a stress induction predicted internalizing behaviors in 152 typically developing children (<i>M</i>_age = 7.82 years, 73 girls, 81.6% White). Results revealed a significant interaction between changes in overall FAA and changes in RSA from baseline to a stressor in predicting children's internalizing behaviors. Specifically, increases in overall FAA from baseline to stress induction were associated with greater internalizing behaviors in children who also exhibited a decrease in RSA from baseline to stress induction. When children exhibited an increase in RSA from baseline to stress induction, increases in overall FAA were associated with relatively fewer internalizing behaviors. Findings highlight that measures indexing central and peripheral nervous system activity may jointly influence stress regulation and contribute to vulnerability to internalizing behaviors in middle childhood.</p>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70192","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148826029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Role of Alexithymia in the Relationship Between Childhood Trauma and Premenstrual Syndrome","authors":"Paul W. Savoca,&nbsp;Julia Ditzer,&nbsp;Anna-Lena Zietlow,&nbsp;Bridget L. Callaghan","doi":"10.1002/dev.70191","DOIUrl":"https://doi.org/10.1002/dev.70191","url":null,"abstract":"<p>Premenstrual syndrome (PMS) is a common and often debilitating condition characterized by emotional, cognitive, and physical symptoms that significantly impact well-being. Research suggests that childhood trauma is associated with heightened PMS symptoms, yet the mechanisms underlying this relationship remain unclear. Alexithymia—a trait marked by difficulties in identifying and expressing emotions—may serve as a key psychological pathway linking childhood trauma to PMS, but this role for alexithymia has not yet been well characterized. Using cross-sectional data from <i>N</i> = 117 women, we assessed childhood trauma exposure (six-item Childhood Trauma Questionnaire), alexithymia (Toronto Alexithymia Scale-20), and premenstrual symptoms (Premenstrual Symptoms Questionnaire). We used mediation analysis to test a proposed causal pathway between childhood trauma, alexithymia, and PMS that can be validated in future studies with longitudinal designs. Childhood trauma predicted higher alexithymia scores (<i>Betas</i> = 0.24, <i>p</i> = 0.009), which in turn predicted increased PMS symptoms (<i>Betas</i> = 0.40, <i>p</i> &lt; 0.001). We further found evidence for a significant indirect effect of childhood trauma on PMS through alexithymia (<i>Betas</i> = 0.10, SE = 0.05, 95% CI [0.003, 0.20]). These findings highlight alexithymia as a critical factor in the link between childhood trauma and PMS, suggesting that difficulties in emotion processing may exacerbate premenstrual symptom severity. Addressing alexithymia in clinical interventions may improve PMS management, particularly in individuals with trauma histories. Future research should further investigate these associations longitudinally and assess targeted interventions for PMS that address alexithymia in individuals with a history of childhood trauma.</p>","PeriodicalId":11086,"journal":{"name":"Developmental psychobiology","volume":"68 5","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/dev.70191","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148784069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}