Current Eye Research最新文献

{"title":"Effect of Meibomian Gland Expression on Optical Quality in Patients with Meibomian Gland Dysfunction.","authors":"Hongzhe Li, Wentao Tong, Man Hu, Ziqi Meng, Pingjun Chang, Yune Zhao","doi":"10.1080/02713683.2025.2497324","DOIUrl":"https://doi.org/10.1080/02713683.2025.2497324","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the changes in meibomian gland function, ocular surface parameters, and optical quality before and after meibomian gland expression in patients with meibomian gland dysfunction (MGD).</p><p><strong>Methods: </strong>Patients with MGD underwent meibomian gland expression once weekly for 4 consecutive weeks. Comprehensive assessments, including the Ocular Surface Disease Index questionnaire, tear break-up time, corneal fluorescein staining, lid margin abnormality grading, meibum expressibility and quality evaluations, Schirmer I test (SIT), as well as optical quality examinations using the Pentacam and Optical Quality Analysis System II, were conducted before and after the treatment.</p><p><strong>Results: </strong>124 eyes of 62 patients were included in the study. Most meibomian gland function and ocular surface parameters showed significant improvement after treatment. Except for and coma (<i>p</i> = .029), no other significant changes in optical quality were observed. Changes in SIT were significantly correlated with changes in total corneal high-order aberrations (tHOA-4mm) (<i>r</i> = -.224, <i>p</i> = .019). Changes in objective scattering index were significantly associated with changes in spherical aberration (<i>r</i> = .219, <i>p</i> = .022), trefoil (<i>r</i> = .797, <i>p</i> < .001), total high-order aberrations (<i>r</i> = .408, <i>p</i> < .001) and total corneal spherical aberration (<i>r</i> = .590, <i>p</i> < .001).</p><p><strong>Conclusion: </strong>Meibomian gland expression effectively improves meibomian gland function and ocular surface parameters. However, it does not appear to significantly impact optical quality in patients with MGD.</p>","PeriodicalId":10782,"journal":{"name":"Current Eye Research","volume":" ","pages":"1-6"},"PeriodicalIF":1.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Capsular Tension Ring Implantation on Postoperative Rotational Stability and Visual Performance of a Multifocal Toric Intraocular Lens.","authors":"Jiao Qi, Xiaoxin Hu, Wenwen He, Keke Zhang, Jiaqi Meng, Yi Lu, Xiangjia Zhu","doi":"10.1080/02713683.2025.2495219","DOIUrl":"https://doi.org/10.1080/02713683.2025.2495219","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the effect of capsular tension ring (CTR) implantation on postoperative rotational stability and visual performance of a plate-haptic multifocal toric intraocular lens in highly and non-highly myopic eyes.</p><p><strong>Methods: </strong>Consecutive cataract patients intended for phacoemulsification and plate-haptic multifocal toric IOL (AT LISA 909 M) implantation were enrolled and randomized to receive either co-implantation of a CTR or not. Axial length (AL) ≥ 26 mm was defined as highly myopic (HM) eyes. At 3 months postoperatively, IOL rotation degree, residual astigmatism, visual acuity, higher-order aberrations, modulation transfer function, dysfunctional lens index (DLI), and quality of vision index (QVI) were assessed.</p><p><strong>Results: </strong>This prospective cohort study included 44 eyes with CTR implanted and 43 without. In HM eyes, the CTR group showed significantly smaller degree of IOL rotation and less residual astigmatism compared to the non-CTR group, however, no such differences were found in non-HM eyes (both <i>p</i> > 0.05). Furthermore, in HM eyes, despite no difference in visual acuity, the CTR group exhibited significantly lower spherical aberrations and higher DLI and QVI compared to the non-CTR group (all <i>p</i> < 0.05), although no such differences were observed in non-HM eyes (all <i>p</i> > 0.05). Multivariate analysis identified longer AL, larger white-to-white, and non-use of CTR as independent risk factors for greater IOL rotation.</p><p><strong>Conclusions: </strong>The co-implantation of CTR improves the rotational stability of a multifocal toric IOL in HM eyes, hence subsequently enhancing visual quality.</p>","PeriodicalId":10782,"journal":{"name":"Current Eye Research","volume":" ","pages":"1-8"},"PeriodicalIF":1.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seven-Year Observation of Posterior Corneal Elevations After Small Incision Lenticule Extraction in Myopic Patients with Thin Corneas.","authors":"Weijung Ten, Fei Xia, Shengtao Liu, Bingqing Sun, Zimeng Zhai, Xingtao Zhou, Jing Zhao","doi":"10.1080/02713683.2025.2495217","DOIUrl":"https://doi.org/10.1080/02713683.2025.2495217","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the long-term stability of the posterior corneal surface in myopic patients with thin corneas after Small Incision Lenticule Extraction (SMILE).</p><p><strong>Methods: </strong>This study involved 60 eyes from 60 patients (mean spherical equivalent (SE): -5.81 ± 1.79 D), divided into two groups based on preoperative central corneal thickness (CCT): Group A (CCT < 510 μm, thin cornea) and Group B (CCT ≥ 510 μm, normal cornea), with 30 eyes per group. Data collected preoperatively and 7 years postoperatively included visual acuity, SE, efficacy and safety indices, intraocular pressure, axial length, and posterior corneal surface elevation measured by Pentacam.</p><p><strong>Results: </strong>No significant long-term complications were observed. Efficacy and safety indices were similar: 0.94 ± 0.16 and 1.07 ± 0.11 in Group A, and 0.94 ± 0.17 and 1.07 ± 0.16 in Group B. In Group A, posterior central elevation (PCE) increased significantly from baseline, while posterior thinnest elevation (PTE) decreased. Group B showed a significant increase in mid-peripheral elevation at 4 mm (MPE-4 mm). Subgroup analysis revealed increased PTE and MPE-6 mm in low-to-moderate myopia in Group A, and increased peripheral elevations in similar myopia levels in Group B. High myopia patients showed no significant changes. Correlation analysis in Group A showed that changes in 7-year PTE were negatively correlated with residual bed thickness (RBT) and positively correlated with the ablation ratio (AR). Similarly, changes in PCE and PTE correlated with RBT and AR.</p><p><strong>Conclusion: </strong>SMILE effectively corrects myopia long-term but increases posterior surface elevation in thin corneas. Patients with high myopia and thin corneas should monitor RBT and AR to ensure long-term corneal stability and safety.</p>","PeriodicalId":10782,"journal":{"name":"Current Eye Research","volume":" ","pages":"1-9"},"PeriodicalIF":1.7,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective Telemedicine Postoperative Protocol Following Microincision Vitrectomy Surgery (MIVS).","authors":"Heun Min, Noraliz Garcia-O'Farrill, Patricia Garcia, Andrew Thomson, Allan A Hunter","doi":"10.1080/02713683.2025.2490768","DOIUrl":"https://doi.org/10.1080/02713683.2025.2490768","url":null,"abstract":"<p><strong>Purpose: </strong>Retrospective studies show a low proportion of postoperative (PO) complications or alterations in management after Microincision Vitrectomy Surgery (MIVS). To our knowledge, this is the first prospective analysis of a telemedicine alternative to the standard practice for PO visits after MIVS. The purpose of this study is to evaluate telemedicine for the management of postoperative visits (POV) following MIVS.</p><p><strong>Methods: </strong>Ongoing randomized, prospective study with 53 patients assigned (1:1) to two arms of POV schedules including Virtual Telemedicine visits (VT) <i>vs.</i> In-person Telemedicine (IP) visits. POV schedules in both groups included visits on the same day after surgery and week(s) 1, 2, 8, and 12. Complete exams with visual acuity, intraocular pressure, and dilated fundus exams of the operative eye were performed by the retina surgeon on day 0, weeks 2 and 12 in both groups. Protocolized focused undilated exams on weeks 1 and 8 either remotely (VT group) or in-person (IP group). Statistical analyses included Mann-Whitney U tests between groups using Microsoft Excel.</p><p><strong>Results: </strong>Primary outcome, mean POV logMAR BCVA, showed no statistically significant difference (<i>p</i>-value = 0.70) between VT and IP groups. Other pre- and post-surgical comparisons (e.g. IOP, RNFL score) showed no statistical differences. No post-surgical complications have been noted.</p><p><strong>Conclusions: </strong>Telemedicine-assisted POV may be a safe and convenient alternative for patients undergoing uncomplicated MIVS, but additional and larger studies are needed.</p>","PeriodicalId":10782,"journal":{"name":"Current Eye Research","volume":" ","pages":"1-7"},"PeriodicalIF":1.7,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Refractory Glaucoma, a New Surgical Paradigm: Review of the Literature.","authors":"Victoria Heintz, Paul Bastelica, Christophe Baudouin, Yves Lachkar, Antoine Labbé","doi":"10.1080/02713683.2025.2494799","DOIUrl":"https://doi.org/10.1080/02713683.2025.2494799","url":null,"abstract":"<p><strong>Purpose: </strong>To review current therapeutic strategies and innovations in the management of refractory glaucoma, with a focus on recent advancements in implantable surgical devices.</p><p><strong>Methods: </strong>A comprehensive literature search across PubMed, Embase, and Cochrane Library, included terms such as \"refractory glaucoma,\" \"posterior drainage implants,\" \"cyclodestruction,\" and \"minimally invasive glaucoma surgery.\" Articles discussing surgical and medical interventions, as well as device innovations, were included.</p><p><strong>Results: </strong>Therapeutic options include creating new sites for filtering surgery, posterior drainage implants, minimally invasive devices, cyclodestruction, or continuing medical management without surgery.</p><p><strong>Conclusion: </strong>Therapeutic decisions regarding refractory glaucoma should be made on a thoughtful, individualized basis, carefully weighing the expected benefits against the potential risks for the patient. Recent innovations in implantable devices expand the range of surgical possibilities.</p>","PeriodicalId":10782,"journal":{"name":"Current Eye Research","volume":" ","pages":"1-14"},"PeriodicalIF":1.7,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on the Study of \"Expression of PAX6 and Keratocyte-Characteristic Markers in Human Limbal Stromal Cells of Congenital Aniridia and Healthy Subjects, In Vitro\".","authors":"Sücattin İlker Kocamış, Bedia Kesimal","doi":"10.1080/02713683.2025.2494797","DOIUrl":"https://doi.org/10.1080/02713683.2025.2494797","url":null,"abstract":"","PeriodicalId":10782,"journal":{"name":"Current Eye Research","volume":" ","pages":"1-2"},"PeriodicalIF":1.7,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In Vivo</i> Dose-Response Effect of 300 nm UV Radiation on the Ocular Lens Epithelial Cells Count.","authors":"Zhaohua Yu","doi":"10.1080/02713683.2025.2490771","DOIUrl":"https://doi.org/10.1080/02713683.2025.2490771","url":null,"abstract":"<p><strong>Purpose: </strong>To assess how varying doses of ultraviolet radiation affect the distribution of lens epithelial cells.</p><p><strong>Methods: </strong>Forty Sprague Dawley rats were exposed unilaterally to ultraviolet radiation-300 nm at doses of 1, 3, 6, and 8 kJ/m². One week after exposure, lenses from both the exposed and the unexposed contralateral eyes were collected for analysis. A midsagittal section from each lens was stained with 4',6-diamidino-2-phenylindole and examined using fluorescence microscopy to evaluate lens epithelial cell distribution.</p><p><strong>Results: </strong>The difference in lens epithelial cell density between exposed and non-exposed eyes at doses of 1, 3, 6, and 8 kJ/m² was measured as 95% confidence interval values of -0.1 ± 2.1, 0.1 ± 3.0, -4.1 ± 1.4, and -2.9 ± 2.7 cell·μm^-1·10^-2, respectively. Data were analyzed using a linear model with the initial density difference set to zero. The slope of the dose-response relationship was estimated as 95% confidence interval -0.4 ± 0.1 cell·μm·kJ^-1·10¹⁰.</p><p><strong>Conclusion: </strong>Exposure to ultraviolet radiation-300 nm reduces lens epithelial cell density. The linear model provides a quantitative understanding of the relationship between ultraviolet radiation dose and cell density.</p>","PeriodicalId":10782,"journal":{"name":"Current Eye Research","volume":" ","pages":"1-6"},"PeriodicalIF":1.7,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparison of the 360° Versus 180° of Selective Laser Trabeculoplasty (SLT) in the Treatment of Open Angle Glaucoma (OAG) and Ocular Hypertension (OHT): A Comprehensive Systematic Review and Meta-Analysis.","authors":"Dillan Cunha Amaral, Jaime Guedes, Pedro Henrique Santana Moreira, Sacha Pereira, Lucas Neves de Oliveira, Ana Luiza Machado Ribeiro Pimentel, Karina de Oliveira Caneca, Mário Luiz Ribeiro Monteiro, Ricardo Noguera Louzada","doi":"10.1080/02713683.2025.2485223","DOIUrl":"https://doi.org/10.1080/02713683.2025.2485223","url":null,"abstract":"<p><strong>Purpose: </strong>There are several divergences in the literature regarding the safety and effectiveness of selective laser trabeculoplasty application at 360° vs. 180°. This systematic review and meta-analysis aimed to compare the efficacy and safety of selective laser trabeculoplasty at 180° and 360° in open-angle glaucoma and ocular hypertension.</p><p><strong>Methods: </strong>This systematic review and meta-analysis, registered with International Prospective Register of Systematic Reviews (CRD42024501311), conducted searches in PubMed, Embase, Web of Science, and Cochrane Library from inception to January 2024. The protocol is registered in International Prospective Register of Systematic Reviews under the same registration number. Primary outcomes included mean intraocular pressure change at 1, 6, 12, and 24 months, success ratio, and adverse events. Statistical analysis utilized R version 4.3.2 (R Foundation for Statistical Computing, Vienna, Austria).</p><p><strong>Results: </strong>The meta-analysis included nine studies, involving 1065 eyes. Compared to 180° selective laser trabeculoplasty, 360° selective laser trabeculoplasty demonstrated superior success ratios (odds ratio 1.63; <i>p</i> = .002) and intraocular pressure reduction at 1 (mean difference -0.99; <i>p</i> < .01), 6 (mean difference -1.37; <i>p</i> < .01), and 12 (mean difference -1.41; <i>p</i> < .01) months. Although the intraocular pressure difference at 24 months was not statistically significant, a subgroup analysis showed that one study influenced heterogeneity and effect size. Adverse event rates did not significantly differ between the groups.</p><p><strong>Conclusion: </strong>360° selective laser trabeculoplasty is preferred for initial laser therapy in open-angle glaucoma and ocular hypertension. It achieves maximal intraocular pressure reduction while maintaining an excellent safety profile.</p>","PeriodicalId":10782,"journal":{"name":"Current Eye Research","volume":" ","pages":"1-11"},"PeriodicalIF":1.7,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Waveform Score Influences the Outcome Metrics of the Ocular Response Analyzer in Patients with Keratoconus and in Healthy Controls.","authors":"Phillip T Yuhas, Maddison M Fortman, Michael Nye, Ashraf M Mahmoud, Cynthia J Roberts","doi":"10.1080/02713683.2025.2489607","DOIUrl":"https://doi.org/10.1080/02713683.2025.2489607","url":null,"abstract":"<p><strong>Purpose: </strong>To test whether the intraocular-pressure (IOP) and biomechanical outcome metrics from the Ocular Response Analyzer (ORA) differ between the measurement with the highest waveform score and the average of four measurements of any waveform score in participants with keratoconus and in controls.</p><p><strong>Methods: </strong>Patients with diagnosed keratoconus and healthy controls were recruited prospectively. Four measurements were made using a third-generation ORA. Goldmann-correlated IOP (IOPg), corneal-compensated IOP (IOPcc), corneal hysteresis (CH), corneal resistance factor (CRF), waveform score, and six waveform parameters (p1area, p2area, w1, w2, h1, and h2) were considered as outcome metrics. In the left eye, outcomes from the measurement with the highest waveform score were compared against averaged outcomes from four measurements of any waveform score using either paired t-tests or Wilcoxon signed-rank tests. Receiver operating characteristic (ROC) curves tested ability of both data-selection approaches to differentiate the cohorts.</p><p><strong>Results: </strong>One-hundred ninety-two (<i>N</i> = 192) participants were enrolled. In the control cohort (<i>n</i> = 145), waveform score, CH, p2area, and h2 were all significantly greater for the best-waveform-score measurement than for the average-waveform-score measurement. IOPcc and w2 were significantly less for the best-waveform-score measurement than for the average-waveform-score measurement. In the keratoconus cohort (<i>n</i> = 47), waveform score, p1area, p2area, h1, and h2 were all significantly greater for the best-waveform-score measurement than for the average-waveform-score measurement. W2 was significantly less for the best-waveform-score measurement than for the average-waveform-score measurement. The area under the ROC curve was high for both data-selection approaches.</p><p><strong>Conclusion: </strong>In general, the best measurement had higher and narrower waveform peaks than the averaged measurement, which suggests better alignment between the device and the eye in the former than in the latter. Thus, making multiple measurements and then analyzing the one with the single highest quality may be preferred to analyzing the average of the group.</p>","PeriodicalId":10782,"journal":{"name":"Current Eye Research","volume":" ","pages":"1-10"},"PeriodicalIF":1.7,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlations of Thioredoxin and Thioredoxin Interacting Protein with Type 2 Diabetes Mellitus Complicated with Diabetic Retinopathy.","authors":"Jiasu Liu, Xuebin Yu, Maryam Chudhary, Hui Qi, Na Zhang, Shiwen Zhong, Qi Zhao, Xiang Ren, Hui Kong, Li Kong","doi":"10.1080/02713683.2025.2487069","DOIUrl":"https://doi.org/10.1080/02713683.2025.2487069","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the relationship between Thioredoxin (Trx), Thioredoxin interacting protein (Txnip), and the severity of diabetic retinopathy (DR).</p><p><strong>Methods: </strong>The study involved a total of 101 eyes, comprising of 31 healthy controls, 24 diabetic patients with no clinically detectable retinopathy (NDR group), 26 patients with non-proliferative DR (NPDR group), and 20 patients with proliferative DR (PDR group), including 62 males and 49 females, average aged 61.65 ± 9.4. Retinal morphology was evaluated using spectral domain optical coherence tomography (SD-OCT), while retinal function was assessed using full-field electroretinogram (ffERG) to record the amplitudes and implicit time. The correlation between serum Trx, Txnip, and DR was analyzed using Spearman correlation analysis.</p><p><strong>Results: </strong>In the early stage of DR, there was no significant difference in macular retinal thickness between groups; in the PDR group, there was a significant increase compared to both the NDR and control groups, particularly in the central fovea (<i>p</i> < 0.0001). Additionally, the amplitude and implicit time of oscillatory potentials exhibited a significant difference between the NDR and control groups at an early stage of DR (<i>p</i> < 0.001). Furthermore, the amplitude of rod and cone ERG decreased significantly in the early stage of DR, while the implicit time began to decline in the NPDR stage. The serum levels of Trx and Txnip exhibited a positive correlation with the progression of DR (<i>r</i> = 0.851, 0.762). Conversely, a negative correlation was observed between the serum levels of Trx and Txnip and the amplitudes of ERG, while a positive correlation was observed with the implicit time of ERG.</p><p><strong>Conclusions: </strong>The serum levels of Trx and Txnip exhibit a positive correlation with retinopathy associated with type 2 diabetes mellitus (T2DM), and thus may be utilized as a potential target for the timely diagnosis and treatment of DR.</p>","PeriodicalId":10782,"journal":{"name":"Current Eye Research","volume":" ","pages":"1-9"},"PeriodicalIF":1.7,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}