Communications Physics最新文献_第2页

Role of cell density and proximity in electroporation for tissue ablation. 细胞密度和邻近度在组织消融电穿孔中的作用。

IF 5.5 1区物理与天体物理

Communications Physics Pub Date : 2026-01-01 Epub Date: 2026-04-20 DOI: 10.1038/s42005-026-02597-5

Lujia Ding, Mike A J Moser, Bing Zhang, Chris Zhang, Ningning Hu

{"title":"Role of cell density and proximity in electroporation for tissue ablation.","authors":"Lujia Ding, Mike A J Moser, Bing Zhang, Chris Zhang, Ningning Hu","doi":"10.1038/s42005-026-02597-5","DOIUrl":"10.1038/s42005-026-02597-5","url":null,"abstract":"Electroporation has advanced significantly in biomedical applications, particularly in tissue ablation. While the influence of individual cellular features, such as cell size and nucleus-to-cytoplasm ratio, on ablation is recognized, this study highlights the key role of the cell grouping factor, namely cell density. Experiments using 2D cell monolayers demonstrated a density-dependent ablation effect: higher cell density significantly elevates resistance to electroporation, evident from reduced ablation areas and ~30% higher lethal electric thresholds (LETs). To explain this, a cell-cell proximity electroporation model was established representing cell density by intercellular distance and degree of containment. It indicated significant inhibition when cells were closely spaced (0-2 µm), with lower pore density and reduced pore area ratios (PARs). This inhibitory effect decays logarithmically as spacing increases, persisting over several cell diameters. Furthermore, fully surrounded cells exhibit a 33% lower PAR than isolated cells, consistent with the observed LET gap between high- and low-density populations. As such, the shielding effect from neighboring cells leads to the density-dependent electroporation at cellular scale and may therefore account for the density-dependent ablation observed at tissue scale. In light of this, considering tissue-specific cell density are critical for better mimicking in vivo conditions, and improving precision in electroporation-based tissue therapies.","PeriodicalId":10540,"journal":{"name":"Communications Physics","volume":"9 1","pages":"211"},"PeriodicalIF":5.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13283845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148307286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One-milligram torsional pendulum toward experiments at the quantum-gravity interface. 一毫克的扭摆朝向量子引力界面的实验。

IF 5.5 1区物理与天体物理

Communications Physics Pub Date : 2026-01-01 Epub Date: 2026-01-30 DOI: 10.1038/s42005-026-02514-w

Sofia Agafonova, Pere Rosselló, Manuel Mekonnen, Onur Hosten

引用次数: 0

Reconfigurable free-space mode generation and detection enabled by an active photonic integrated circuit coupled to a passive mode-selective interface. 可重构的自由空间模式生成和检测由一个有源光子集成电路耦合到一个无源模式选择接口。

IF 5.5 1区物理与天体物理

Communications Physics Pub Date : 2026-01-01 Epub Date: 2026-03-05 DOI: 10.1038/s42005-026-02522-w

Aleksandr Boldin, Ultan J Daly, Maziyar Milanizadeh, Rakan Alsaigh, Zhaozhong Chen, David A B Miller, Francesco Morichetti, Martin P J Lavery

{"title":"Reconfigurable free-space mode generation and detection enabled by an active photonic integrated circuit coupled to a passive mode-selective interface.","authors":"Aleksandr Boldin, Ultan J Daly, Maziyar Milanizadeh, Rakan Alsaigh, Zhaozhong Chen, David A B Miller, Francesco Morichetti, Martin P J Lavery","doi":"10.1038/s42005-026-02522-w","DOIUrl":"10.1038/s42005-026-02522-w","url":null,"abstract":"Optical mode-sorting and generation are used for a wide range of quantum, sensing and communication applications. High-speed switching between mode sets would allow photonics systems to react to changes in propagation channel in real time. Photonic-Integrated-Circuits (PICs) with phased arrays can rapidly reconfigure their function at MHz depending on installed modulators. As a reconfigurable photonic system, PIC can reconfigure significantly fast than spatial light modulators that are limited to less than 1 kHz. However, phased-arrays are bound by two-dimensional Nyquist-sampling limit and spacing between array elements leads to grating lobe formation, where many additional array elements are needed to mitigate these effects. We leverage a passive Multiple-Plane-Light-Converters (MPLC) as an Optical Mode-Selective Interface (OMSI), coupling a basis set of free-space Hermite Gaussian (HG) modes directly into an active optical mesh implemented on a PIC. The active mesh can generate or sort any free-space mode-set that can be created by a linear superposition of 15 HG modes. Without changing the physical system, we demonstrate the generation and sorting of four orthogonal mode groups, each with 15 modes, achieving a mean intermodal crosstalk for sorting of -22 dB. This approach can allow for rapidly reconfigurable mode-sorters that could be used for quantum or classical communications or sensing applications.","PeriodicalId":10540,"journal":{"name":"Communications Physics","volume":"9 1","pages":"133"},"PeriodicalIF":5.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13083242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147721919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Injection locking of Rydberg dissipative time crystals. Rydberg耗散时间晶体的注入锁定。

IF 5.5 1区物理与天体物理

Communications Physics Pub Date : 2026-01-01 Epub Date: 2026-03-18 DOI: 10.1038/s42005-026-02585-9

Darmindra Arumugam

{"title":"Injection locking of Rydberg dissipative time crystals.","authors":"Darmindra Arumugam","doi":"10.1038/s42005-026-02585-9","DOIUrl":"10.1038/s42005-026-02585-9","url":null,"abstract":"Non-equilibrium Rydberg gases exhibit exotic many-body phases stabilized by the interplay of coherent interactions and dissipation. Strong Rydberg interactions drive sustained limit cycle oscillations, whose robustness, long-range temporal order, and spontaneous time-translation symmetry breaking establish a dissipative time crystal (DTC). Collective self-entrainment in driven ensembles leads to global synchronization and a dominant oscillation frequency. Here, injection locking of a Rydberg DTC is demonstrated using a radio-frequency (RF) electric field that gradually pulls the intrinsic oscillation toward the injected frequency. Above a critical threshold, full synchronization occurs, with the locking bandwidth scaling linearly with RF amplitude. This includes synchronization of higher-order harmonics, revealing entrainment of the system's nonlinear temporal dynamics. The phenomenon parallels injection locking in classical nonlinear systems, but emerges here in a strongly interacting quantum medium. This approach establishes a new method for stabilizing and controlling time-crystalline temporal order, with applications in precision sensing, quantum metrology, and timekeeping.","PeriodicalId":10540,"journal":{"name":"Communications Physics","volume":"9 1","pages":"156"},"PeriodicalIF":5.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13149303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147867185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Projected entangled pair states for lattice gauge theories with dynamical fermions. 具有动态费米子的点阵规范理论的投射纠缠对态。

IF 5.8 1区物理与天体物理

Communications Physics Pub Date : 2026-01-01 Epub Date: 2026-01-08 DOI: 10.1038/s42005-025-02482-7

Ariel Kelman, Umberto Borla, Patrick Emonts, Erez Zohar

引用次数: 0

Regarding the existence of abelian fractional topological insulators in twisted MoTe₂ and related systems. 关于扭曲MoTe2及相关体系中存在阿贝尔分数阶拓扑绝缘子的问题。

IF 5.8 1区物理与天体物理

Communications Physics Pub Date : 2026-01-01 Epub Date: 2026-01-16 DOI: 10.1038/s42005-025-02483-6

Yves H Kwan, Glenn Wagner, Jiabin Yu, Andrea Kouta Dagnino, Yi Jiang, Xiaodong Xu, B Andrei Bernevig, Titus Neupert, Nicolas Regnault

{"title":"Regarding the existence of abelian fractional topological insulators in twisted MoTe2 and related systems.","authors":"Yves H Kwan, Glenn Wagner, Jiabin Yu, Andrea Kouta Dagnino, Yi Jiang, Xiaodong Xu, B Andrei Bernevig, Titus Neupert, Nicolas Regnault","doi":"10.1038/s42005-025-02483-6","DOIUrl":"10.1038/s42005-025-02483-6","url":null,"abstract":"The experimental discovery of fractional Chern insulators (FCIs) in moiré materials raises the question of whether their time-reversal invariant analogs, fractional topological insulators (FTIs), can also be realized in these platforms. We address this via exact diagonalization calculations in both a Landau level (LL) model and continuum model for twisted MoTe2, and extract principles for engineering FTIs in realistic conditions. For the spinful LL model at filling <math><mi>ν</mi> <mo>=</mo> <mfrac><mrow><mn>1</mn></mrow> <mrow><mn>3</mn></mrow> </mfrac> <mo>+</mo> <mfrac><mrow><mn>1</mn></mrow> <mrow><mn>3</mn></mrow> </mfrac> </math> , we show that a suppression of the short-range component of the interaction is important to stabilize the FTI. For twisted MoTe2 at <math><mi>ν</mi> <mo>=</mo> <mo>-</mo> <mfrac><mrow><mn>4</mn></mrow> <mrow><mn>3</mn></mrow> </mfrac> </math> , we find that a short-range attraction g on top of the screened Coulomb interaction is needed to realize an FTI. We discuss how this threshold value of g could be reduced by examining larger system sizes, incorporating band-mixing effects, exploiting Landau level character, and engineering the dielectric environment. While our study highlights the challenges, at least for the fillings considered, for obtaining FTIs, we also provide potential sample-engineering routes to improve the stability of FTI phases.","PeriodicalId":10540,"journal":{"name":"Communications Physics","volume":"9 1","pages":"52"},"PeriodicalIF":5.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12893902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146200392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Droplet removal by capillary lifting. 毛细管提升法去除液滴。

IF 5.5 1区物理与天体物理

Communications Physics Pub Date : 2026-01-01 Epub Date: 2026-06-12 DOI: 10.1038/s42005-026-02714-4

Ke Sun, Jack R Panter, Alvin C M Shek, Yonas Gizaw, Kislon Voïtchovsky, Halim Kusumaatmaja

引用次数: 0

Amorphous silicon-carbide photonics for ultrasound imaging. 超声成像用非晶碳化硅光子学。

IF 5.8 1区物理与天体物理

Communications Physics Pub Date : 2026-01-01 Epub Date: 2025-12-18 DOI: 10.1038/s42005-025-02456-9

R Tufan Erdogan, Bruno Lopez-Rodriguez, Wouter J Westerveld, Sophinese Iskander-Rizk, Gerard J Verbiest, Iman Esmaeil Zadeh, Peter G Steeneken

{"title":"Amorphous silicon-carbide photonics for ultrasound imaging.","authors":"R Tufan Erdogan, Bruno Lopez-Rodriguez, Wouter J Westerveld, Sophinese Iskander-Rizk, Gerard J Verbiest, Iman Esmaeil Zadeh, Peter G Steeneken","doi":"10.1038/s42005-025-02456-9","DOIUrl":"10.1038/s42005-025-02456-9","url":null,"abstract":"Photonic ultrasound sensors promise unparalleled spatial and temporal resolution in ultrasound imaging due to their size-independent noise figure, high sensitivity, and broad bandwidth. Optical materials can further improve performance and stability, but achieving small size, high sensitivity, and wide bandwidth remains challenging. This work introduces amorphous silicon carbide (a-SiC) for ultrasound sensing, offering strong optical confinement, low propagation loss, and high stability for miniaturized microring sensors. We demonstrate a compact detection system with a 20-transducers linear array coupled to a single bus waveguide. The sensors achieve an optical finesse of 1320 and intrinsic sensitivity of 78 fm kPa-1, leading to a noise-equivalent pressure below 55 <math><mi>mPa</mi> <mo>/</mo> <msqrt><mrow><mi>Hz</mi></mrow> </msqrt> </math> , calibrated from 3.36 MHz to 30 MHz. High-resolution imaging of fine structures validates real-world applicability. a-SiC is also easily integrated on most substrates due to its low deposition temperature. Our results position a-SiC as a promising solution for optical ultrasound sensing, combining miniaturization, low-loss, and high-sensitivity.","PeriodicalId":10540,"journal":{"name":"Communications Physics","volume":"9 1","pages":"25"},"PeriodicalIF":5.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12819153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

De-aberration for noninvasive transcranial photoacoustic computed tomography through an adult human skull. 通过成人颅骨的无创经颅光声计算机断层成像去像差。

IF 5.5 1区物理与天体物理

Communications Physics Pub Date : 2026-01-01 Epub Date: 2026-02-14 DOI: 10.1038/s42005-026-02545-3

Yousuf Aborahama, Karteekeya Sastry, Manxiu Cui, Yang Zhang, Yilin Luo, Rui Cao, Geng Ku, Jigmi Basumatary, Junhao Zhu, Siying Kong, Lihong V Wang

{"title":"De-aberration for noninvasive transcranial photoacoustic computed tomography through an adult human skull.","authors":"Yousuf Aborahama, Karteekeya Sastry, Manxiu Cui, Yang Zhang, Yilin Luo, Rui Cao, Geng Ku, Jigmi Basumatary, Junhao Zhu, Siying Kong, Lihong V Wang","doi":"10.1038/s42005-026-02545-3","DOIUrl":"10.1038/s42005-026-02545-3","url":null,"abstract":"Noninvasive transcranial photoacoustic computed tomography (PACT) of the human brain, despite its clinical potential as a complementary technology to functional MRI, remains impeded by the acoustic distortion induced by the human skull. The distortion, which is attributed to the markedly different material properties of the skull relative to soft tissue, results in heavily aberrated PACT images. Herein, we report an experimental demonstration of the de-aberration of PACT images through an ex-vivo adult human skull using a homogeneous elastic model for the skull. Using only the geometry, position, and orientation of the skull, obtained from adjunct imaging data and fiducial markers, we faithfully de-aberrate the PACT images of light-absorbing phantoms acquired through an ex-vivo human skull for different levels of phantom complexity and positions. We also demonstrate the generality of our results by attaining a similar extent of de-aberration through a second ex-vivo human skull. Our work addresses the longstanding challenge of skull-induced aberrations in transcranial PACT and advances the field towards unlocking the full potential of transcranial human brain PACT.","PeriodicalId":10540,"journal":{"name":"Communications Physics","volume":"9 1","pages":"116"},"PeriodicalIF":5.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13043303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A universal framework for the quantum simulation of Yang-Mills theory. Yang-Mills理论量子模拟的通用框架。

IF 5.5 1区物理与天体物理

Communications Physics Pub Date : 2026-01-01 Epub Date: 2026-02-19 DOI: 10.1038/s42005-025-02421-6

Jad C Halimeh, Masanori Hanada, Shunji Matsuura, Franco Nori, Enrico Rinaldi, Andreas Schäfer

{"title":"A universal framework for the quantum simulation of Yang-Mills theory.","authors":"Jad C Halimeh, Masanori Hanada, Shunji Matsuura, Franco Nori, Enrico Rinaldi, Andreas Schäfer","doi":"10.1038/s42005-025-02421-6","DOIUrl":"10.1038/s42005-025-02421-6","url":null,"abstract":"Quantum computers promise to simulate complex quantum field theories that are intractable for classical computers, potentially revealing new physics in strongly interacting systems. Current approaches for simulating Yang-Mills gauge theories face significant technical barriers due to complex group structures and complicated truncation schemes that vary drastically between different theories. Here we show that the orbifold lattice formulation provides a universal framework for quantum simulation of Yang-Mills theories with arbitrary gauge groups and dimensions. Our approach reduces all theories to the same simple Hamiltonian form, enabling implementation with standard quantum gates regardless of system complexity. We demonstrate explicit quantum circuits using only controlled-NOT and single-qubit operations, with concrete resource estimates for time evolution algorithms. This universal framework simplifies quantum simulation of gauge theories and enables systematic scaling to larger systems on fault-tolerant quantum computers.","PeriodicalId":10540,"journal":{"name":"Communications Physics","volume":"9 1","pages":"67"},"PeriodicalIF":5.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12916482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147270048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0