Andrea Laureti, Tiago Marques, João Pitta, Vincent Fehmer, Irena Sailer, Alessandro Pozzi, Luís Azevedo
{"title":"Influence of Horizontal Intraoral Scan Bodies on the Trueness of Digital Impressions for Complete-Arch Prostheses on Four Implants: An In Vitro Evaluation","authors":"Andrea Laureti, Tiago Marques, João Pitta, Vincent Fehmer, Irena Sailer, Alessandro Pozzi, Luís Azevedo","doi":"10.1111/clr.70001","DOIUrl":"10.1111/clr.70001","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To assess the impact of horizontal intraoral scan bodies (H-ISBs) on the trueness of complete-arch digital impressions compared to vertical ISBs (V-ISBs). To evaluate trueness among four intraoral scanners (IOS) and inter-operator variability across different ISB × IOS combinations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Digital impressions were made from a dental cast with four multi-unit analogs using four H-ISBs: H-NB, H-NS, H-M6, H-SF, and a V-ISB (V-EA) as a comparison. Two operators performed 10 scans per ISB with four IOS devices (i5D, PS, T3, T4), generating 400 impressions. Reference scans were obtained with a desktop scanner, and trueness was analyzed using root-mean-square (RMS) error calculations (<i>α</i> = 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>H-NS and H-SF exhibited the highest trueness across IOSs, whereas H-NB and H-M6 showed lower trueness. V-EA outperformed H-NB and H-M6 but not H-NS and H-SF. Significant IOS-ISB interaction effects (<i>p</i> < 0.01) indicated H-SF as the most accurate, especially with PS. T4 and i5D displayed greater variability, particularly with H-NB. V-ISBs exhibited higher inter-operator variability compared to H-ISBs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>H-ISBs did not perform better than V-ISBs in all scenarios. The interactions among ISB design, IOS type, and operator significantly affect the digital impression trueness. The discrepancies measured among the systems remain well below the currently accepted threshold for clinically relevant misfit, supporting the suitability of the horizontal configuration for complete-arch impressions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"36 10","pages":"1287-1295"},"PeriodicalIF":5.3,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144664264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Panagiotis Ntovas, Piyarat Sirirattanagool, Praewvanit Asavanamuang, Shruti Jain, Lorenzo Tavelli, Marta Revilla-León, Maria Eliza Galarraga-Vinueza
{"title":"Accuracy and Time Efficiency of Artificial Intelligence-Driven Tooth Segmentation on CBCT Images: A Validation Study Using Two Implant Planning Software Programs","authors":"Panagiotis Ntovas, Piyarat Sirirattanagool, Praewvanit Asavanamuang, Shruti Jain, Lorenzo Tavelli, Marta Revilla-León, Maria Eliza Galarraga-Vinueza","doi":"10.1111/clr.70003","DOIUrl":"10.1111/clr.70003","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To assess the accuracy and time efficiency of manual versus artificial intelligence (AI)-driven tooth segmentation on cone-beam computed tomography (CBCT) images, using AI tools integrated within implant planning software, and to evaluate the impact of artifacts, dental arch, tooth type, and region.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Fourteen patients who underwent CBCT scans were randomly selected for this study. Using the acquired datasets, 67 extracted teeth were segmented using one manual and two AI-driven tools. The segmentation time for each method was recorded. The extracted teeth were scanned with an intraoral scanner to serve as the reference. The virtual models generated by each segmentation method were superimposed with the surface scan models to calculate volumetric discrepancies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The discrepancy between the evaluated AI-driven and manual segmentation methods ranged from 0.10 to 0.98 mm, with a mean RMS of 0.27 (0.11) mm. Manual segmentation resulted in less RMS deviation compared to both AI-driven methods (CDX; BSB) (<i>p</i> < 0.05). Significant differences were observed between all investigated segmentation methods, both for the overall tooth area and each region, with the apical portion of the root showing the lowest accuracy (<i>p</i> < 0.05). Tooth type did not have a significant effect on segmentation (<i>p</i> > 0.05). Both AI-driven segmentation methods reduced segmentation time compared to manual segmentation (<i>p</i> < 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>AI-driven segmentation can generate reliable virtual 3D tooth models, with accuracy comparable to that of manual segmentation performed by experienced clinicians, while also significantly improving time efficiency. To further enhance accuracy in cases involving restoration artifacts, continued development and optimization of AI-driven tooth segmentation models are necessary.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"36 10","pages":"1312-1323"},"PeriodicalIF":5.3,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144664266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of Residual Bone Level Around Explanted Implants and Description of the Systemic and Local Characteristics. A Retrospective Study","authors":"Rodrigo Martin-Cabezas, Norbert Cionca, Catherine Giannopoulou","doi":"10.1111/clr.70004","DOIUrl":"10.1111/clr.70004","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The study aimed to evaluate the residual bone level of explanted implants and to report local and systemic characteristics observed in patients who underwent implant explantation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A total of 494 administrative records were initially retrieved from the database. After elimination of duplicates, 464 medical records of patients who underwent implant explantation between 2005 and 2021 in thirteen private clinics in Switzerland were screened. Information regarding implant history, local (oral health, periodontal and prosthetic status) and systemic (systemic diseases, medication, and smoking) characteristics was assessed through the medical records and the radiographic data. ISRCTN registry (ISRCTN10631004).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In total, 399 patients and 521 implants were included in the analysis. Peri-implantitis was the most frequent reason for explantation (62%). Explantation was mainly performed in cases of advanced peri-implantitis with a mean bone loss of 62.92% of the implant length. Most patients had radiographic bone loss around the remaining dentition with a bone loss/age ratio of 0.74, presented compromised oral health, and 47.80% of them were smokers. Moreover, only 56.12% of patients reported being in good systemic health.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Implant explantations were typically performed once bone loss reached approximately 60% of the implant length. They were most often observed in advanced cases of peri-implantitis and in patients with high-risk profiles for periodontal breakdown, such as a history of periodontal disease or heavy smoking habits.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"36 10","pages":"1324-1334"},"PeriodicalIF":5.3,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144639951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Paula Da Rosa Possebon, Fernando Antônio Vargas Júnior, Fernanda Isabel Román Ramos, Otacílio Luiz Chagas-Júnior, Luciana de Rezende Pinto, Fernanda Faot
{"title":"Functional, Patient-Centered and Bone Remodeling Outcomes in Two Narrow-Diameter Implant Retained Mandibular Overdenture Wearers After 5 Years of Follow-Up: A Prospective Case Series","authors":"Anna Paula Da Rosa Possebon, Fernando Antônio Vargas Júnior, Fernanda Isabel Román Ramos, Otacílio Luiz Chagas-Júnior, Luciana de Rezende Pinto, Fernanda Faot","doi":"10.1111/clr.14471","DOIUrl":"10.1111/clr.14471","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This prospective longitudinal case series investigated changes in functional, radiographic, and patient-centered outcomes in users of two narrow-diameter implant-retained mandibular overdentures (IMO) over a 5-year follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Twenty-four patients from a previous 3-year study (8 man, 16 women, 71.58 ± 7.03 years, mean mandibular edentulism duration 23.9 ± 14.4 years) were invited for a 5-year follow-up evaluation of radiographic and functional parameters. Masticatory function (MF) was assessed using the Swallowing Threshold Test (ST), with X50 and B cut-off values indicating satisfactory performance. Oral health-related quality of life (OHRQoL) was evaluated using the OHIP-Edent questionnaire. The Posterior Mandibular Area Index (PAI) was analyzed using digital panoramic radiographs. Data was analyzed using multilevel mixed-effects linear regression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty participants completed the 5-year follow-up evaluation. ST_X50 (4.00–3.70; <i>p</i> ≤ 0.01; 95% CI: 0.47–1.82) reached a significant reduction along with an increased number of masticatory cycles (59.33–65.60; <i>p</i> ≤ 0.01; 95% CI: 0.32–1.11) between years. The number of IMO wearers presenting satisfactory mastication increased but persisted as unsatisfactory in nine participants by year 5. Declines in the Functional Limitation and Physical Disability domains of OHRQoL were noted, with unsatisfactory mastication correlating with higher pain (coef: 2.5; <i>p</i>: 0.03; 95% CI: 0.25–4.74) and psychological disability scores (coef: 0.94; <i>p</i> ≤ 0.01; 95% CI: 0.19–1.68). PAI increased significantly (1.13–1.68; <i>p</i> ≤ 0.01; 95% CI: 0.24–0.56), indicating ongoing bone remodeling.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Although MF and bone parameters improved over 5 years, persistent unsatisfactory mastication continued to negatively affect quality of life. These findings underscore the interdependence between functional and patient-centered outcomes in IMO users.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>The Brazilian Registry of Clinical Trials (ReBEC), Trial identification: UTN code: U1111-1259-4127</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"36 10","pages":"1261-1270"},"PeriodicalIF":5.3,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.14471","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144611219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiographic Peri-Implant Bone Changes in Osteoporotic Women Treated With a Ti-Zr, Bone Level Tapered Implant With a Hydrophilic Surface: A 12-Month Prospective Case-Series","authors":"Calciolari Elena, Mardas Nikos, Palaska Iro, Tagliaferri Sara, Donos Nikolaos","doi":"10.1111/clr.14469","DOIUrl":"10.1111/clr.14469","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study assessed 12-month post-loading 3D peri-implant radiographic bone changes in osteoporotic women receiving a single titanium-zirconium bone-level tapered dental implant with a hydrophilic surface.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>This was a prospective case series involving 18 post-menopausal osteoporotic women in need of a single dental implant. A standardized CBCT scan was performed after implant placement and at 12 months post-loading to assess peri-implant bone changes. The Implant Stability Quotient (ISQ) was recorded after implant placement, at implant impression, loading, and 12 months post-loading. Peri-implant clinical parameters were recorded at 6 and 12 months post-loading and during the last visit implant survival and success were also evaluated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Seventeen patients completed all study visits, and implant placement was uneventful for all participants. A statistically significant difference (reduction) from implant placement to 12 months post-loading was observed in terms of radiographic buccal bone width and palatal/lingual width (ΔBw-0: 0.53 mm, <i>p</i> < 0.001 and ΔPw-0: 0.47 mm, <i>p</i> = 0.006), as well as in terms of vertical distance between the implant shoulder and the first bone to implant contact on the buccal and palatal/lingual aspect (ΔBICb: −0.26 mm, <i>p</i> = 0.005 and ΔBICp: −0.46 mm, <i>p</i> = 0.018). ISQ increased during osseointegration, and a high implant survival (100%) and success rate (from 81.3% to 100% based on 3 different sets of criteria) were recorded at 12 months post-loading.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In this case series, osteoporotic patients treated with single titanium-zirconium implants showed high survival rates, predictable 12-month implant outcomes, and physiologic peri-implant bone remodelling.</p>\u0000 \u0000 <p><b>Trial Registration:</b> NCT02884401</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"36 10","pages":"1234-1247"},"PeriodicalIF":5.3,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.14469","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caroline Streichfuss, Stefan Wolfart, Lukas Waltenberger
{"title":"Influence of Bone Density and Guide Protocol on the Accuracy of Self-Cutting Implants Using Static Guided Implant Placement—An In Vitro Study","authors":"Caroline Streichfuss, Stefan Wolfart, Lukas Waltenberger","doi":"10.1111/clr.14470","DOIUrl":"10.1111/clr.14470","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>To investigate the influence of bone density and guide protocol on the accuracy of static guided implant placement of self-cutting implants in vitro.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 242 implant replicas of self-cutting implants and implants with a tapered design as a control were placed in 40 maxilla replica models with healed posterior ridges differing in bone density and anterior extraction sockets. After full-guided osteotomy, the implants in the healed ridge were either placed through the template or freehand. In anterior extraction sockets, a pilot-guided group was additionally investigated. Postoperative scans were superimposed with the planning and investigated for angular, coronal, and apical deviation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>For 3D coronal deviation, the study indicates significantly lower deviations in soft bone (<i>p</i> < 0.01) and for guided implant placement (<i>p</i> < 0.01) in posterior sites. Apical and angular deviations are significantly influenced by the placement protocol (<i>p</i> ≤ 0.03) and the presence of reference points from neighbouring teeth (<i>p</i> < 0.01). In the anterior site, the coronal deviation seems to be improved by a direct view of the surgical field, while 3D apical and angular accuracy appears to benefit from a high degree of guidance (<i>p</i> < 0.01).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Within the limitations of this in vitro study, for low bone density, immediate implant placement, and in clinically challenging situations without reference to the adjacent teeth, the use of template guidance for insertion statistically significantly reduced deviation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"36 10","pages":"1248-1260"},"PeriodicalIF":5.3,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.14470","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144547222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andreas Stavropoulos, Ahmad Al Said, Ola Mustafa, Loukia M. Spineli, Patrick Heimel, Kristina Bertl
{"title":"Factors Affecting the Efficacy of Airflowing in Cleaning Implant Surfaces in a Surgical Peri-Implantitis Treatment Simulation—A Laboratory Study","authors":"Andreas Stavropoulos, Ahmad Al Said, Ola Mustafa, Loukia M. Spineli, Patrick Heimel, Kristina Bertl","doi":"10.1111/clr.14464","DOIUrl":"10.1111/clr.14464","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate, in a simulation of surgical peri-implantitis treatment, the impact of type of handpiece, device settings, and instrumentation time on the efficacy of airflowing in cleaning the implant surface, depending on the type of bone defect and implant surface.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Turned and modified surface implants (54 each) were coated with biofilm imitation and mounted on resin models replicating purely horizontal or circumferential intraosseous peri-implant defects (both 5 mm deep). Implants were instrumented with an airflowing device using a supra- or submucosal handpiece, with three settings: (a) power 5, 5 s (b) power 10, 5 s, and (c) power 5, 15 s per implant/defect sextant.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The amount of residual biofilm imitation was associated with defect configuration, type of handpiece, and device settings (<i>p</i> < 0.15); implant surface did not have an effect. In horizontal defects, with the supramucosal handpiece, only 3 of 54 implants showed > 5% residual biofilm imitation and 23 of 54 implants were completely clean; with the submucosal handpiece, 12 of 18 implants showed ≤ 5% residual biofilm imitation when used for 15 s/sextant, yet none were completely clean. In intraosseous defects, all implants presented ≤ 5% residual biofilm imitation and 10 of 18 implants were completely clean with the submucosal handpiece used for 15 s/sextant; the supramucosal handpiece was largely inefficacious.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Within the limitations of this laboratory study, peri-implant bone defect configuration should dictate the choice of airflowing handpiece (i.e., for horizontal defects, the supramucosal handpiece; for intraosseous defects, the submucosal handpiece) and intrasurgical airflowing requires a prolonged instrumentation time, but not increased power.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"36 9","pages":"1146-1158"},"PeriodicalIF":5.3,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.14464","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144367978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sila Cagri Isler, Fatma Soysal, Tugce Ceyhanli, Berrin Unsal, Jean-Claude Imber, Andrea Roccuzzo
{"title":"Long-Term Treatment Outcomes of Peri-Implantitis Reconstructive Therapy: 7-Year Survival and Success of a Randomized Clinical Trial","authors":"Sila Cagri Isler, Fatma Soysal, Tugce Ceyhanli, Berrin Unsal, Jean-Claude Imber, Andrea Roccuzzo","doi":"10.1111/clr.14466","DOIUrl":"10.1111/clr.14466","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To report the 7-year outcomes of a randomized clinical trial evaluating a reconstructive surgical procedure of peri-implantitis with a bone substitute in combination with either concentrated growth factor (CGF) or collagen membrane (CM).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>The original population consisted of 57 patients with at least one implant diagnosed with peri-implantitis exhibiting two-, three-, or four-wall intrabony defects ≥ 3 mm which were filled with a xenogenic bone grafting material and covered with either CGF or CM. Clinical and radiographic parameters, treatment success, and disease recurrence frequencies were evaluated over the 7-year follow-up period of supportive periodontal/peri-implant care. Relationships between prognostic indicators/predictors and treatment success and failure were investigated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Sixteen patients (24 implants) (CGF group) and 18 (25 implants) (CM group) completed the 7-year follow-up. Although short-term improvements in clinical and radiographic outcomes were observed, a tendency toward relapse was detected through time. At implant level, CM group demonstrated significantly more favorable outcomes for deepest PPD and radiographic vertical defect depth (<i>p</i> = 0.040 and <i>p</i> = 0.043) compared to CGF group. At 7 years, treatment success was achieved in 23.1% of CGF and 30.8% of CM patients, while disease recurrence occurred in 34.6% and 30.8%, respectively (<i>p</i> > 0.05). The presence of baseline suppuration was the only significant patient-level predictor for treatment failure (OR = 15.45; 95% CI: 1.42–168.5; <i>p</i> = 0.02).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Both protocols led to comparable clinical and radiographic outcomes. Long-term treatment success was limited, with increasing failure rates over time. Baseline suppuration had a significant negative impact on treatment outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"36 10","pages":"1202-1218"},"PeriodicalIF":5.3,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.14466","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Myroslav Solonko, Erik Regidor, Alberto Ortiz-Vigón, Eduardo Montero, Blanca Vilchez, Mariano Sanz
{"title":"Surgical Treatment of Peri-Implantitis Combined With Keratinized Mucosa Augmentation: Results of a Dual-Center 3-Year RCT","authors":"Myroslav Solonko, Erik Regidor, Alberto Ortiz-Vigón, Eduardo Montero, Blanca Vilchez, Mariano Sanz","doi":"10.1111/clr.14465","DOIUrl":"10.1111/clr.14465","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To evaluate the medium-term efficacy of using a xenogeneic collagen matrix to augment the width of the peri-implant keratinized mucosa (PIKM) as an adjunct to the surgical treatment of peri-implantitis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>In this 36-month parallel-arm randomized controlled clinical trial, patients with peri-implantitis were randomly assigned to a combined protocol of resective peri-implantitis surgery and a PIKM augmentation procedure, either with an autologous free gingival graft (FGG) or a collagen matrix (CM). Primary outcomes were the increase in the width of PIKM and probing pocket depth (PPD) reduction at 36 months. As secondary outcomes, radiographic and patient-reported outcomes were assessed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty-one patients (20 in the CM group and 21 in the FGG group) completed the three-year follow-up. PIKM increased in both groups, but the increase was significantly higher in the APF (apically positioned flap) + FGG group compared to the APF + CM group [2.0 (95% CI: 1.3, 2.7) mm in the FGG group compared to 1.0 (95% CI: 0.5, 1.5) mm in the CM group; <i>p</i> = 0.048]. PPDs were reduced by 1.5 mm (95% CI: 1.1, 1.9) and 1.4 mm (95% CI: 0.6, 2.2), respectively. Disease resolution (maximum one site with bleeding on probing, no suppuration, no further bone loss > 0.5 mm, and PD ≤ 5 mm) was 47.6% in the FGG group and 35.0% in the CM group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Tested surgical modalities resulted in similar improvements in the clinical parameters. Both FGG and CM increased the PIKM, but PIKM was greater at the 36-month examination in the FGG group.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"36 9","pages":"1159-1171"},"PeriodicalIF":5.3,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.14465","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144335128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erik Klepsland Mauland, Mehrnaz Beheshti Maal, Elisabeth Lind Melbye, Naomi Østergren Aarbu, Karoline Sørensen, Stig Aanerød Ellingsen, Dagmar Fosså Bunæs, Roya Torabi Gaarden, Anders Verket
{"title":"The Impact of Peri-Implant Diseases and Complications on Oral Health-Related Quality of Life Following Dental Implant Therapy in Norway: A Cross-Sectional Study","authors":"Erik Klepsland Mauland, Mehrnaz Beheshti Maal, Elisabeth Lind Melbye, Naomi Østergren Aarbu, Karoline Sørensen, Stig Aanerød Ellingsen, Dagmar Fosså Bunæs, Roya Torabi Gaarden, Anders Verket","doi":"10.1111/clr.14467","DOIUrl":"10.1111/clr.14467","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To report oral health-related quality of life (OHRQoL) in a sample rehabilitated with dental implants and assess the influence of self-reported implant complications and clinical peri-implant status. A secondary aim was to investigate associations between OHIP-14 scores and patient-related variables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>The Norwegian National Insurance Scheme registry for implant rehabilitation in 2014 was searched, and patients (<i>n</i> = 3083) were mailed a survey including OHIP-14, questions about peri-implant status, and patient-related variables. A subsample was examined clinically (<i>n</i> = 242). Associations of self-reported implant complications and clinical peri-implant status with OHIP-14 scores were evaluated by the Kruskal–Wallis test and logistic regression models.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The OHIP-14 mean sum score reported by the 1299 survey respondents was 4.1 (± 6.4). Self-report of complications was associated with higher OHIP-14 scores in a dose-dependent manner. Lower education (OR 1.54, 95% CI 1.05–2.22), female sex (OR 1.75, 95% CI 1.23–2.56), technical complication(s) (OR 1.58, 95% CI: 1.07–2.34), biological complication(s) (OR 2.41, 95% CI 1.67–3.49) and poor cleansability (OR 2.94, 95% CI 1.64–5.37) were associated (<i>p</i> < 0.05) with higher OHIP-14 mean sum scores in the adjusted regression model. For the 242 patients examined clinically, the OHIP-14 mean sum score was 3.8 (± 6.5). Peri-implant soft tissue dehiscence (OR 2.53, 95% CI 1.17–5.49) was associated with higher OHIP-14 mean sum scores in the adjusted regression model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>OHIP-14 scores were low in this study, indicating good OHRQoL following implant rehabilitation in Norway. Complications lowered OHRQoL in a dose–response manner, confirmed by self-reports of complications and by the presence of peri-implant soft tissue dehiscence.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"36 10","pages":"1219-1233"},"PeriodicalIF":5.3,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.14467","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144320338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}