Clinical Oral Implants Research最新文献

{"title":"A Randomised Controlled Trial Comparing a One-Piece Zirconia Tissue-Level Implant and Two-Piece Titanium Bone-Level Implant for Maxillary Single Tooth Replacement—3 year Results","authors":"J. H. W. de Beus,&nbsp;M. S. Cune,&nbsp;L. Muijselaar,&nbsp;J. W. A. Slot,&nbsp;C. Jensen-Louwerse,&nbsp;S. la Bastide-van Gemert,&nbsp;H. J. A. Meijer,&nbsp;G. M. Raghoebar,&nbsp;U. Schepke","doi":"10.1111/clr.70148","DOIUrl":"10.1111/clr.70148","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This RCT evaluated and compared the clinical performance of zirconia and titanium dental implants placed in the maxillary premolar region. Outcomes were assessed 3 years after prosthetic loading and included marginal bone level (MBL) changes, clinical parameters, aesthetic outcomes, and patient related outcome measures (PROMs).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Fifty patients were randomly allocated to receive either a zirconia one-piece (ZrO₂, <i>n</i> = 25) implant or a titanium bone-level (Ti, <i>n</i> = 25) implant, restored with a lithium disilicate crown 3 months after implant placement. Primary outcome was change in MBL. Secondary outcomes included implant survival, peri-implant tissue health, technical complications, aesthetic outcomes, and PROMs. Examinations were performed 3 years after crown placement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>After 3 years, mean MBL change was −0.02 mm (SD = 0.78) for ZrO₂ and −0.04 mm (SD = 0.36) for Ti; no statistically significant difference was found (<i>p</i> = 0.635). One ZrO₂ implant failed to osseointegrate. Clinical parameters were favourable for both implant types, although slightly higher bleeding scores were observed for ZrO₂. Differences in aesthetic outcomes and PROMs were found, favoring the ZrO₂ implant group. None of these differences reached statistical significance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion and Clinical Implications</h3>\u0000 \u0000 <p>After 3 years of function, the ZrO₂ and Ti implant as applied in this study showed comparable MBL changes. Survival, clinical and aesthetic parameters, and PROMs were generally favourable and largely comparable for both groups. These short-term findings indicate that both implant types represent a viable option for clinical use in this application.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>CCMO registration: NL58957.042.16</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 9","pages":"1069-1080"},"PeriodicalIF":5.9,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70148","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148270598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Implant Design on Fracture Resistance, Mode, and Crystal Structure of One- and Two-Piece Zirconia Implants With Ceramic or Titanium Abutment Screws: An In Vitro Study","authors":"Abdulaziz Gul,&nbsp;Evaggelia Papia,&nbsp;Siamak Eqtesadi,&nbsp;Magnus Anderson,&nbsp;Jonas P. Becktor,&nbsp;Per Vult von Steyern","doi":"10.1111/clr.70149","DOIUrl":"10.1111/clr.70149","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the fracture resistance, fracture modes, and crystalline phase changes of zirconia one-piece implants (OPI) and bone-level (BLTPI) or tissue-level, two-piece implants (TLTPI), with ceramic (C) or titanium (T) abutment screws after dynamic preloading in a moist environment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Dynamic preloading under moist conditions and subsequent static load-to-fracture testing were performed to evaluate fracture resistance and fracture mode. Scanning electron microscopy (SEM) analysis of fracture surfaces was employed to supplement the observations of macroscopic fracture modes. Crystalline phase changes were assessed using micro-Raman spectroscopy. Specimen preparations were performed in accordance with ISO 14801:2016. Five different ceramic (zirconia) implant designs were divided into the following groups: OPI, BLTPI (BLC, BLT), TLTPI (TLC, TLT). One-way and two-way ANOVA tests were used for comparisons and factor effect analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fracture resistance (N) and bending moment (N cm) differed significantly among the implant groups (<i>p</i> &lt; 0.001), following the order TLTPI (775.2 ± 71 N) &gt; OPI (605.7 ± 37 N) &gt; BLTPI (498.3 ± 93 N). Within the two-piece implants (TPI), tissue-level designs (TL) outperformed bone-level designs (BL), while designs with different abutment screw materials showed no significant difference (<i>p</i> = 0.982).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Within the limitations of this in vitro study, the evaluated zirconia-based OPI, BLTPI, and TLTPI systems demonstrate sufficient fracture resistance to support further clinical investigation. Implant-level design (TL vs. BL) influences mechanical performance, whereas the influence of abutment screw material (ceramic vs. titanium) is less pronounced and varies according to the implant-level design.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 9","pages":"1081-1095"},"PeriodicalIF":5.9,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70149","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148249546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Medication Intake on Dental Implant-Related Outcomes—A Scoping Review","authors":"Alberto Monje,&nbsp;Maria Costanza Soldini,&nbsp;Emilio Couso-Queiruga,&nbsp;Álvaro Babiano,&nbsp;Vivianne Chappuis","doi":"10.1111/clr.70151","DOIUrl":"10.1111/clr.70151","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The objective of this scoping review was to evaluate the effect of systemic medications on dental implant outcomes in medically compromised patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Electronic and manual searches were conducted for this scoping review. Clinical studies reporting on systemic medication intake and implant outcomes were eligible. Studies reporting on the use of antiresorptive medications were not included in this scoping review. Qualitative evaluation was performed as meta-analysis was not feasible due to study heterogeneity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Overall, 51 studies met the inclusion criteria and were eligible for assessment. Six medications were identified to potentially impact the short- and long-term implant outcomes. In total, 8 studies reported the intake of anti-hypertensives (AHTNs), 9 studies reported the intake of anticoagulants (ACs), 12 studies reported the intake of immunosuppressants (IMNs), 11 studies reported the intake of nonsteroidal anti-inflammatories (NSAIDs), 12 studies reported the intake of proton-pump inhibitors (PPIs), and 12 studies reported the intake of selective serotonin reuptake inhibitors (SSRIs). Moreover, 1 study reported pooled data regarding the use of PPIs, SSRIs, AHTNs, and statins. From these, the following results were drawn: ACs, long-term NSAID use, prolonged use of PPIs, and SSRIs are associated with increased risk of implant failure and/or marginal bone loss. Additionally, AHTNs and IMNs have no effect on implant-related outcomes. Medication-related biological implant complications are underreported in the literature.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Medication intake can significantly influence implant-related outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 9","pages":"1033-1056"},"PeriodicalIF":5.9,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70151","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148388624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heat Generation in Guided Implant Osteotomy; Influence of Irrigation Route, Bone Structure, and Measurement Method: A Comparative Thermal Analysis","authors":"Nehal I. Shobair,&nbsp;Zainab Hafez,&nbsp;Rehab A. Soliman,&nbsp;Yassin S. Alian","doi":"10.1111/clr.70147","DOIUrl":"10.1111/clr.70147","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate heat generation during guided implant osteotomy in a standardized in vitro resin-model setup and assess the effects of irrigation technique and model structure on temperature change during drilling.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Standardized solid and bilayered resin mandibular models were fabricated and assigned to no irrigation, external irrigation, or internal irrigation using a 3D-printed guide with irrigation channels. Sequential osteotomy drilling (2.0–4.2 mm) was performed to an 18 mm depth at 1200 rpm. Temperature was measured using infrared thermography and an internal thermistor sensor. Temperature change relative to baseline (Δ<i>T</i>) was the primary outcome.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Bilayered models demonstrated lower Δ<i>T</i> than solid models when assessed by infrared thermography (<i>p</i> = 0.009), whereas thermistor measurements showed less consistent differences between model types. Irrigation significantly reduced Δ<i>T</i>, with internal irrigation producing the lowest values. In solid models, mean Δ<i>T</i> decreased from 31.41°C without irrigation to 9.48°C with external irrigation and 3.50°C with internal irrigation. In bilayered models, Δ<i>T</i> decreased from 13.31°C to 2.45°C and 0.84°C, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Irrigation significantly reduced heat generation during guided implant osteotomy. Internally irrigated guides demonstrated lower temperature change than conventional external irrigation. Bilayered models demonstrated lower temperature changes primarily in infrared thermography measurements and may partially approximate differences in thermal behavior between cortical and trabecular structures under the present experimental conditions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 9","pages":"1057-1068"},"PeriodicalIF":5.9,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148223615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Adjunctive Use of Er:YAG Laser or Erythritol Air-Polishing in the Non-Surgical Treatment of Peri-Implantitis: A Pilot RCT","authors":"Marco Clementini,&nbsp;Margherita Minoli,&nbsp;Simone Fabrizi,&nbsp;Isabella De Rubertis,&nbsp;Nicola Discepoli,&nbsp;Massimo de Sanctis","doi":"10.1111/clr.70153","DOIUrl":"10.1111/clr.70153","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Evaluate the efficacy of adjunctive mechanical/physical decontamination to non-surgical submarginal instrumentation in patients with peri-implantitis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Patients with at least one implant diagnosed with peri-implantitis were included in this 6-month single-masked randomized clinical trial with three parallel groups: non-surgical submarginal instrumentation with titanium curettes (control); control plus erythritol air-polishing (test 1) and control plus Er:YAG laser (test 2). Clinical variables were collected at baseline, 1, 3 and 6 months. The primary outcome was probing pocket depth (PPD) reduction. Secondary outcomes included bleeding on probing (BoP) reduction and endpoint of therapy (implants with PPD ≤ 5 mm, BoP ≤ 1 site, no suppuration). A multilevel logistic model was computed to evaluate the predictive value of implant- and patient-level variables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty-seven patients (84 implants) were enrolled. PPD reductions were observed in all groups (mean: 1–1.4 mm at 1 month), remaining stable at 3 months, with slight relapse at 6 months. All treatments led to significant BoP reduction (24%–36%) at 1 month, with no further significant changes at later follow-ups and no intergroup differences. Therapeutic endpoint rates were 12%–18%. Multilevel analysis suggested an association between the presence of ≥ 2 mm vestibular keratinized mucosa and the use of Er:YAG with higher odds of achieving treatment success. Healing was uneventful in all groups, except for one case of surgical emphysema associated with erythritol air-polishing.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Irrespective of the adjunctive treatment modality, achievement of peri-implantitis therapeutic endpoint was limited across groups. Possible associations with treatment outcomes were observed; these findings require confirmation in larger studies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>ClinicalTrials.gov identifier: NCT03451981</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 9","pages":"1118-1128"},"PeriodicalIF":5.9,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148365310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjunctive Electrolytic Implant Surface Decontamination in the Reconstructive Surgical Treatment of Peri-Implantitis—A Randomized Clinical Trial","authors":"Erik Regidor,&nbsp;Alberto Ortiz-Vigón,&nbsp;Jessica Berglundh-Gottlieb,&nbsp;Jan Derks,&nbsp;Kostas Bougas","doi":"10.1111/clr.70152","DOIUrl":"10.1111/clr.70152","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The aim of this study was to evaluate the adjunctive effect of electrolytic cleaning in the surgical treatment of peri-implantitis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A total of 40 patients (44 implants) with peri-implantitis-associated intra-bony defects were included in this single-center randomized controlled trial. Surgical decontamination of implant surfaces was initiated by use of a rotating titanium brush. Following random allocation, adjunctive electrolytic cleaning was performed in the test group. Xenogeneic bone substitute and a resorbable collagen membrane were then used in both groups. Clinical parameters including probing pocket depth (PPD), bleeding/suppuration on probing, buccal mucosal recession (REC), and keratinized mucosa were assessed at 6 and 12 months. Radiographic marginal bone levels (MBL) and patient-reported outcomes (PROs) were evaluated at 12 months. The primary outcome was a composite measure including implant survival, complete absence of BoP/SoP, PPD ≤ 5 mm and REC ≤ 1 mm at 12 months.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>At 12 months, no implants were lost. The composite outcome was complete at 27.3% of control and 40.0% of test implants (<i>p = 0.41</i>). Mean PPD reductions were 4.5 ± 2.6 mm (control) and 3.8 ± 2.3 mm (test), while MBL gains were 1.9 ± 2.4 mm and 2.1 ± 2.0 mm, respectively. No significant intergroup differences were observed for any clinical, radiographic or PROs. Post-surgical complications occurred in the test group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Clinical, radiographic and patient-reported outcomes of surgical therapy of peri-implantitis were favorable at 12 months. The adjunctive use of electrolytic cleaning provided no added benefit over the use of a rotating titanium brush alone.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <p><b>Trial Registration:</b> ISRCTN17197337 (ISRCTN)</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 9","pages":"1109-1117"},"PeriodicalIF":5.9,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148335892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Block Versus Particulate Deproteinized Bovine Bone Mineral for Guided Bone Regeneration of Peri-Implant Dehiscence Defects: A 5-Year Randomized Controlled Trial","authors":"Anina N. Zuercher,&nbsp;Erkan Evci,&nbsp;Riccardo D. Kraus,&nbsp;Ronald E. Jung,&nbsp;Franz J. Strauss,&nbsp;Goran Benic","doi":"10.1111/clr.70150","DOIUrl":"10.1111/clr.70150","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <p>To assess the 5-year dimensional stability of buccal hard-tissues following guided bone regeneration (GBR) of peri-implant dehiscence defects using deproteinized bovine bone mineral (DBBM) blocks or particulate.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients requiring single-tooth implants and presenting a buccal dehiscence defect (≥ 3 mm) at implant placement were randomly allocated to GBR using either particulate DBBM or an individually shaped DBBM-block, both covered with a resorbable collagen membrane. Buccal hard-tissue thickness was assessed using cone-beam computed tomography postoperatively, at 6 months and at 5 years. Buccal horizontal thickness at the implant shoulder and corono-buccal thickness measured at 45° were recorded. Secondary outcomes included marginal bone levels, clinical parameters and implant survival. Linear mixed-effects models were used to compare the groups to account for within-subject correlations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-two of 24 patients completed the 5-year follow-up. Buccal hard-tissue thickness decreased over time in both groups, however, the block-group showed significantly greater dimensional stability. At 5 years, mean buccal horizontal hard-tissue thickness was 1.36 ± 1.16 mm in the block-group and 0.07 ± 0.16 mm in the particulate-group (adjusted mean difference, −1.2 mm; 95% CI, −1.9 to−0.6; <i>p</i> &lt; 0.001). Corono-buccal thickness at 45° was also significantly greater in the block-group (adjusted mean difference, −0.3 mm; 95% CI, −0.5 to −0.1; <i>p</i> = 0.002). Marginal bone levels and clinical parameters showed no clinically relevant differences. No implant loss or peri-implantitis was observed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>GBR using either DBBM blocks or particulate DBBM resulted in similar peri-implant clinical outcomes and implant survival at 5 years. However, DBBM blocks provided superior long-term preservation of the buccal hard-tissue contour.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>Clinical Trial Registration Number, DRKS00005803</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 9","pages":"1096-1108"},"PeriodicalIF":5.9,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70150","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148336174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 3-Year Split-Mouth Randomized Non-Inferiority Controlled Trial Comparing Cement-Retained Monolithic CAD-CAM Zirconia and Lithium Disilicate Crowns for Single Posterior Implant Restorations","authors":"Xiaosong Yi,&nbsp;Donghao Wei,&nbsp;Shuman Quan,&nbsp;Yingjie Kong,&nbsp;Xi Huang,&nbsp;Xi Jiang,&nbsp;Ye Lin,&nbsp;Ping Di","doi":"10.1111/clr.70154","DOIUrl":"10.1111/clr.70154","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate whether monolithic CAD-CAM lithium disilicate (LS₂) crowns are non-inferior to monolithic CAD-CAM zirconia (ZrO₂) crowns with respect to clinical and radiographic outcomes in single posterior implant restorations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Patients with bilateral single-tooth implants at homologous posterior sites were enrolled. Each implant was randomly assigned to receive either a monolithic CAD-CAM ZrO₂ crown (Control) or a LS₂ crown (Test), both cemented onto customized titanium abutments. Marginal bone level change (ΔMBL) was the primary outcome. Non-inferiority of LS₂ relative to ZrO₂ was evaluated using a prespecified margin of −0.5 mm for the paired difference in ΔMBL (LS₂−ZrO₂). Implant and prosthesis survival, biological and technical complications, periodontal parameters, and FIPS were assessed as secondary outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 40 patients completed the 3-year follow-up. The survival rates were 97.5% for ZrO₂ and 100% for LS₂, with one implant loss in the ZrO₂ group. Biological complication rates were 5% for ZrO₂ and 15% for LS₂ (<i>p =</i> 0.219), while technical complication rates were 2.5% and 5% (<i>p =</i> 1.000), respectively. No crown fractures, chipping, or debonding were found in either group. The ΔMBL was −0.62 ± 1.22 mm for ZrO₂ and −0.36 ± 1.07 mm for LS₂. The paired mean difference in ΔMBL (LS₂−ZrO₂) was 0.26 mm (95% CI: −0.17 to 0.70 mm). The lower confidence limit remained above the prespecified non-inferiority margin of −0.5 mm, demonstrating non-inferiority of LS₂ with respect to ΔMBL. No statistically significant differences were observed in mSBI, mPLI, or FIPS between the two groups (<i>p</i> = 0.106, 0.201, 0.825).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Monolithic CAD-CAM LS₂ crowns exhibit non-inferior clinical and radiographic outcomes to ZrO₂ crowns over a 3-year follow-up period. Customized titanium abutments with cemented monolithic all-ceramic crowns represent a reliable treatment option for single posterior implant-supported restorations in the medium term.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>Chinese Clinical Trial Registry (chictr.org.cn): ChiCTR2200062023</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 9","pages":"1129-1143"},"PeriodicalIF":5.9,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148365311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteogenic Outcomes and Associated Modifiable Factors of 3D ‐Printed Individual Titanium Mesh Exposure: A Retrospective Analysis","authors":"Minxue Yang, Yaxin Bai, Yuling Yang, Yujie Zhu, Houqi Zhou, Yuanding Huang, Tao Chen","doi":"10.1111/clr.70171","DOIUrl":"https://doi.org/10.1111/clr.70171","url":null,"abstract":"Objective To identify independent risk factors for titanium mesh exposure following 3D‐printed individualized titanium mesh (3D‐PITM)‐assisted alveolar bone augmentation and to evaluate the impact of exposure on bone regeneration outcomes. Method This retrospective study included 52 patients with severe alveolar bone defects who underwent 3D‐PITM‐assisted guided bone regeneration (GBR) between January 2019 and August 2025, comprising 25 patients with mesh exposure and 27 without. Demographic characteristics and surgery‐related variables were collected; univariate analysis and multivariate logistic regression were performed to identify independent risk factors. Additionally, this study measured bone volume, bone height, and bone width at different time points to evaluate the impact of 3D‐PITM exposure on bone augmentation. Results The results showed that smoking, thin gingival biotype, and maxillary defects were significantly associated with mesh exposure ( <jats:italic>p</jats:italic> &lt; 0.05): smoking (OR = 5.16, 95% CI: 1.28–20.82, <jats:italic>p</jats:italic> = 0.021), thin gingival biotype (OR = 4.21, 95% CI: 1.05–16.82, <jats:italic>p</jats:italic> = 0.042), and maxillary defects (OR = 11.49, 95% CI: 1.25–105.68, <jats:italic>p</jats:italic> = 0.031). Regarding bone augmentation, the exposure group showed significantly greater resorption in bone volume ( <jats:italic>p</jats:italic> = 0.0063), height ( <jats:italic>p</jats:italic> &lt; 0.0001), and width ( <jats:italic>p</jats:italic> &lt; 0.0001) than the nonexposure group. Moreover, early exposure resulted in more severe bone loss than late exposure across bone volume ( <jats:italic>p</jats:italic> = 0.0048), height ( <jats:italic>p</jats:italic> = 0.0019), and width ( <jats:italic>p</jats:italic> &lt; 0.0001). Conclusion This study found that 3D‐PITM exposure significantly impairs bone regeneration, with smoking, thin gingival biotype, and maxillary defects identified as independent risk factors. Preoperative identification of these risk factors may help reduce mesh exposure and improve bone augmentation outcomes.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"16 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148842924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Outcomes of Fixed Dental Prostheses Supported by Teeth or Implants in the Posterior Region—A Long‐Term Retrospective Multicenter Study","authors":"Zahra Athab Abduljabbar, Lars Hjalmarsson, Victoria Franke Stenport, Jir Barzangi, Anders Magnuson, Alf Eliasson","doi":"10.1111/clr.70169","DOIUrl":"https://doi.org/10.1111/clr.70169","url":null,"abstract":"Background Few long‐term studies compare tooth‐ and implant‐supported fixed dental prostheses (FDPs) in the posterior region. Objectives To compare the 5‐ and 10‐year survival and complication outcomes of tooth‐ and implant‐supported FDPs and to assess patient‐reported effects. Material and Methods This retrospective multicenter clinical study investigates patients treated with 3–5 units tooth‐supported fixed dental prostheses (TSFDPs) and 1–4 units implant‐supported FDPs in the posterior region at two specialist dental clinics (2009–2019) using clinical and radiographical examinations and Oral Health Impact Profile‐14 (OHIP‐14). Survival, biological, and technical complications as well as patient‐reported effects were recorded. Results A total of 180 patients with 238 FDPs: 113 TSFDPs, 71 implant‐supported crowns (ISCs), and 54 implant‐supported fixed partial prostheses (ISFPPs) were examined after a mean follow‐up of 10 years. The 5‐year cumulative survival rate for TSFDPs and implant‐supported FDPs was 98% ( <jats:italic>p</jats:italic> = 0.71). The 10‐year cumulative survival rates were 94% for TSFDPs and 93% for implant‐supported FDPs ( <jats:italic>p</jats:italic> = 0.87). Eight TSFDPs, three ISCs, and five ISFPPs failed. Biological complications were recorded in 24.8% of TSFDPs and in 9.6% of implant‐supported FDPs ( <jats:italic>p</jats:italic> = 0.012). Technical complications were recorded in 29.9% of TSFDPs and in 27% of implant‐supported FDPs ( <jats:italic>p</jats:italic> = 0.62). Low OHIP‐14 scores were reported in patients with tooth‐supported (4.8 ± 6.7), implant‐supported (3 ± 4.3), and with both types of FDPs (3.5 ± 3.6). Scores that indicate a good OHRQoL. Conclusion Tooth‐ and implant‐supported FDPs had high survival rates after 5 and 10 years. Biological complications had the highest impact on prostheses failure.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"9 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148768314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}