Clinical Oral Implants Research最新文献

{"title":"Premature Occlusal Contacts Induce MRONJ in Osseointegrated Dental Implants: An Experimental In Vivo Study","authors":"Eun‐Bin Bae, Ahana Goswami, Jun Yaung, Soo Yeon Kim, Sherry S. Baik, Kaylyn A. Yu, Chan Park, Jung‐Bo Huh, Jae‐Young Kim, Christine Y. Hong, Sol Kim, Reuben H. Kim","doi":"10.1111/clr.70191","DOIUrl":"https://doi.org/10.1111/clr.70191","url":null,"abstract":"Objectives Medication‐related osteonecrosis of the jaw (MRONJ) is a debilitating condition associated with antiresorptive agents (ARAs) and can occur around well‐osseointegrated dental implants. Although implant presence–triggered osteonecrosis (IPTO) has been primarily linked to bacteria‐related peri‐implantitis, whether occlusal trauma contributes to IPTO remains unclear. Therefore, this study developed a novel premature occlusal contact (POC) mouse implant model to evaluate the effect of occlusal trauma on MRONJ development around osseointegrated implants. Material and Methods Eighteen mice underwent bilateral maxillary first molar extraction followed by immediate implant placement. After a 3‐week healing period to allow osseointegration, mice were randomized to receive intravenous zoledronic acid (ZOL, 125 μg/kg) or saline vehicle (Veh) twice weekly ( <jats:italic>n</jats:italic> = 9 per group). One week later, POC was induced in a split‐mouth design by applying composite resin to one implant, whereas the contralateral implant served as a control. After 5 weeks of occlusal loading, mice were euthanized for μCT and histological analyses. Results μCT analysis revealed that POC reduced radiographic bone‐to‐implant contact (rBIC) in both Veh‐ and ZOL‐treated mice. POC significantly increased empty lacunae around the implant neck in Veh‐treated mice, whereas in ZOL‐treated mice, POC induced extensive circumferential bone necrosis around the implant, accompanied by increased macrophage infiltration. No significant differences in peptidoglycan (PGN)‐positive signals were observed among the experimental groups. Conclusion These findings suggest that POC contributes to peri‐implant osteonecrosis under ZOL treatment, supporting occlusal trauma as an important local factor in MRONJ development around osseointegrated dental implants.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"12 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149226485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Host‐Derived and Microbiological Biomarkers for the Detection of Peri‐Implant Bone Loss: A Diagnostic Accuracy Study","authors":"Marion Arce, Cristina Lima, Leire Virto, Juan Daniel Gamonal, Diogo Banaco, Mario Romandini, Mariano Sanz","doi":"10.1111/clr.70193","DOIUrl":"https://doi.org/10.1111/clr.70193","url":null,"abstract":"Aim To evaluate the diagnostic accuracy of host‐derived and microbiological biomarkers, alone and in combination with clinical parameters, for the detection of peri‐implant bone loss (BL). Methods A university‐based cohort of subjects with dental implants was examined at baseline and after a mean follow‐up of 3.9 years. Peri‐implant BL served as the reference standard, defined as &gt; 1 mm between baseline and follow‐up radiographs; implants with &lt; 0.5 mm BL served as controls. At follow‐up, peri‐implant crevicular fluid and submarginal‐microbiological samples were collected. Bone metabolism and inflammatory biomarkers were quantified using Luminex technology. Bacterial loads were quantified by qPCR. Associations of biomarkers with BL were evaluated using multilevel logistic regression models. Diagnostic accuracy was assessed using ROC curves, with AUC, sensitivity, specificity, and predictive values reported. Results Seventy‐one subjects with 273 implants were included. Twenty‐eight exhibited peri‐implant‐BL &gt; 1.0 mm over the follow‐up period. Increased levels of IL‐1β, <jats:italic>T. denticola, Fusobacterium</jats:italic> spp., and <jats:italic>T. forsythia</jats:italic> were associated with BL in unadjusted analyses. However, these associations were no longer statistically significant after adjustment for clinical parameters. Individual biomarkers demonstrated limited diagnostic accuracy (maximum AUC = 0.68). In contrast, biomarker combinations with clinical parameters exhibited excellent discriminative performance (AUC &gt; 0.95). The combination of IL‐1β and BoP‐or‐PPD achieved the highest accuracy (AUC = 0.97). Conclusions While individual biomarkers showed limited diagnostic utility, combining multiple predictors significantly improved the ability to detect peri‐implant BL. Combining IL‐1β with either BoP or PPD significantly outperformed individual clinical measures but did not outperform the combination of clinical parameters, highlighting the potential of integrated biomarker and clinical parameter approaches as screening tools for detecting BL.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"6 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149226388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Masseter Muscle Volume and Cross‐Sectional Area as Risk Factors for Late Mechanical Dental Implant Failure: A Matched Case–Control Study","authors":"Hee‐Sun Choi, Eun‐Chong Lee, Eun‐Kyoung Pang","doi":"10.1111/clr.70188","DOIUrl":"https://doi.org/10.1111/clr.70188","url":null,"abstract":"Objectives This study aimed to investigate whether three‐dimensional (3D) masseter muscle morphology—volume and cross‐sectional area (CSA)—is associated with the risk of late mechanical dental implant failure and to derive preliminary cut‐off values for risk stratification. Material and Methods This 1:4 matched case–control study investigated 23 cases of late mechanical failure (fixture fracture, screw fracture, or abutment fracture) and 92 successful controls. Participants were matched by gender, age (±10 years), anatomical location, and maintenance period (±2 years). Masseter morphology was quantified using the 3D reconstruction of the cone‐beam computed tomography (CBCT) data. Independent risk factors were determined using a multivariable generalized estimating equation model adjusting for potential confounders. Results Increased masseter muscle bulk was significantly associated with mechanical failure ( <jats:italic>p</jats:italic> &lt; 0.001). The odds of mechanical failure increased by 1.24‐fold per 1000 mm <jats:sup>3</jats:sup> increase in masseter volume and by 1.11‐fold per 10 mm <jats:sup>2</jats:sup> increase in CSA. ROC analysis demonstrated AUCs of 0.846 for masseter volume and 0.871 for CSA. The maximum‐Youden thresholds were 31,272.56 mm <jats:sup>3</jats:sup> for volume and 691.30 mm <jats:sup>2</jats:sup> for CSA, with sensitivities of 86.96% and 82.61% and specificities of 77.17% and 79.35%, respectively. Internal bootstrap validation yielded AUC 95% confidence intervals of 0.751–0.931 and 0.767–0.951, respectively. Conclusions Greater masseter muscle volume and CSA were significantly associated with late mechanical implant failure in this matched case–control study. The proposed cut‐off values may provide preliminary reference values for risk stratification. However, these findings should be regarded as exploratory and require prospective validation in independent cohorts before routine clinical implementation.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"16 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Accuracy of Complete Arch Implant Scans Recorded by Using a Customized Metallic Ring‐Based Calibrated Framework: An In Vivo Study","authors":"Miguel Gómez‐Polo, Solange Vasquez‐Ramos, Marta Revilla‐León, Rocío Cascos","doi":"10.1111/clr.70192","DOIUrl":"https://doi.org/10.1111/clr.70192","url":null,"abstract":"Aim To evaluate and compare the positional accuracy of complete arch intraoral digital implant scans obtained using a conventional scan body protocol and a customized metallic ring‐based calibrated framework. Materials and Methods A completely edentulous arch restored with six implants was scanned using two complete arch intraoral digital impression protocols: a conventional scan body protocol (SB) and a metallic ring‐based calibrated framework (CF). Twenty scans were obtained per group using the same intraoral scanner. A coordinate measuring machine (CMM) dataset served as the reference standard. All STL files were imported into dental CAD software to design a standardized virtual implant‐supported bar, which was subsequently analyzed using reverse engineering software. Linear inter‐implant distances and angular deviations were calculated. Trueness was defined as the absolute deviation from the CMM reference, and precision as the variability among repeated scans. Between‐group comparisons were performed using independent <jats:italic>t</jats:italic> ‐tests with Welch correction and Holm adjustment ( <jats:italic>α</jats:italic> = 0.05). Results The mean linear deviation was 0.034 (0.004) mm for CF and 0.124 (0.019) mm for SB ( <jats:italic>p</jats:italic> &lt; 0.01). The mean angular deviation was 0.31 (0.05) degrees for CF and 0.55 (0.10) degrees for SB ( <jats:italic>p</jats:italic> &lt; 0.01). Conclusions The calibrated splinting protocol showed greater trueness and lower variability compared with the conventional scan body approach.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"49 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149172547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammasome‐Related Transcriptomic Profiles in Periodontitis and Peri‐Implantitis Reveal a Shared Inflammatory Framework: A Cross‐Sectional Study","authors":"Miguel Padial‐Molina, David Herrera‐Garcia, Pablo Galindo‐Fernandez, Pablo Antonio Lopez‐Galindo, Julio Jauregui, Natividad Martín‐Morales, Allinson Olaechea, Federico Zurita, Ana Belén Carrillo‐Gálvez, Francisco O'Valle, Pablo Galindo‐Moreno","doi":"10.1111/clr.70190","DOIUrl":"https://doi.org/10.1111/clr.70190","url":null,"abstract":"Objectives To compare clinical, histological, immunohistochemical, and targeted gene‐expression features related to inflammasome signaling across healthy tissues, periodontitis, and peri‐implantitis. Materials and Methods This exploratory cross‐sectional study included supracrestal soft‐tissue biopsies from 6 healthy controls, 17 periodontitis, and 18 peri‐implantitis lesions. Evaluations included clinical data, histomorphometric collagen quantification, immunohistochemical staining (CD45, NLRP3, AIM2, CASP1, IL‐1β), and targeted digital transcriptomic profiling of 20 preselected inflammasome‐related genes using the NanoString nCounter platform. Data were analyzed using non‐parametric statistics and FDR‐corrected correlation matrices. Results Periodontitis and peri‐implantitis showed greater clinical inflammation, reduced collagen content, and increased inflammatory infiltrate compared with healthy tissues. Peri‐implantitis displayed the more severe clinical phenotype and greater tissue disruption. At the molecular level, disease‐associated changes were captured by <jats:italic>AIM2</jats:italic> , <jats:italic>CASP1</jats:italic> , <jats:italic>IL1B</jats:italic> , <jats:italic>GBP5</jats:italic> , <jats:italic>TXNIP</jats:italic> , <jats:italic>CGAS</jats:italic> , <jats:italic>STING1</jats:italic> , and <jats:italic>PANX1</jats:italic> rather than <jats:italic>NLRP3</jats:italic> alone. Except for a minor pairwise difference in <jats:italic>CGAS</jats:italic> ( <jats:italic>p</jats:italic> = 0.031), individual gene expression did not differ between the diseased states. Stratified correlation analyses demonstrated coordinated within‐group co‐expression networks among priming, sensor, and effector transcripts, reflecting descriptive pathway patterns within each clinical cohort. Conclusions Periodontitis and peri‐implantitis share a substantial inflammasome‐related host‐response framework. Rather than revealing a distinct inflammasome program, peri‐implantitis exhibits a largely overlapping molecular profile that occurs within a clinically more severe and structurally more disrupted lesion environment. These findings suggest that the biological distinction between the two diseases may lie less in pathway identity than in the tissue context in which a shared inflammatory machinery is expressed.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"7 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149172546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three‐Year Follow‐Up of Clinical, Radiographic, and Patient‐Reported Outcomes for Zirconia and Titanium Implants in the Posterior Region: A Randomized Controlled Trial","authors":"Anina N. Zuercher, Ronald E. Jung, Stefan P. Bienz, Stephanie A. Wenk, Daniel S. Thoma, Marc Balmer","doi":"10.1111/clr.70176","DOIUrl":"https://doi.org/10.1111/clr.70176","url":null,"abstract":"Objective To compare the 3‐year clinical, radiographic, esthetic, and patient‐reported outcomes of zirconia (Zr) and titanium (Ti) implants placed in posterior sites in a randomized, controlled within‐subject design. Materials and Methods Forty‐two patients each received one Zr and one Ti implant. Clinical and radiographic outcomes were evaluated at baseline, 1, and 3 years after crown delivery. Marginal bone levels (MBL), peri‐implant soft‐tissue parameters, technical complications, esthetic outcomes (Δ <jats:italic>E</jats:italic> values, VAS scores), and patient‐reported measures were assessed. Thirty‐nine patients (37 Zr; 39 Ti implants) were available at 3 years. Results The 3‐year survival rate was 100% for Ti and 94.9% for Zr implants. MBL remained stable after the initial remodeling phase, with no clinically relevant differences between materials. Peri‐implant soft‐tissue conditions (BOP, plaque presence, PD, KT) were similar for Zr and Ti. Two zirconia implants were lost during the observation period. Peri‐implantitis was diagnosed in 7.9% of the implants, affecting three titanium and three zirconia implants. Technical complications differed between groups: chipping occurred significantly more often at Zr implant‐supported crowns. Ti implants showed two screw‐loosening events, while Zr implants showed two cases of decementation. Esthetic and patient‐reported outcomes were comparable, with low perceived mucosal color differences and a slight preference for Zr sites, if detectable. Conclusion Zr and Ti implants showed similar peri‐implant health, marginal bone stability, esthetic outcomes, and patient satisfaction after 3 years. Zr implants, however, demonstrated a slightly lower survival rate and more chipping. Trial Registration The trial is registered in the German Clinical Trials Register (DRKS) under the ID DRKS00008591","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"8 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149151796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short Dental Implants as Strategic Support for Removable Partial Dentures in Mandibular Free‐End Situations: A 3‐Year Prospective Cohort Study","authors":"Manrique Fonseca, Samir Abou‐Ayash, Simone Janner, Nicole Schenk, Sebastian Hinz, Martin Schimmel, Norbert Enkling","doi":"10.1111/clr.70184","DOIUrl":"https://doi.org/10.1111/clr.70184","url":null,"abstract":"Objectives This study aimed to assess the mid‐term clinical performance of short implants as strategic support for mandibular removable partial dentures (RPDs) with free‐end situations. Methods Subjects wearing lower RPDs in Kennedy Class I situations received two supporting posterior implants. After the healing phase, all participants received ball abutments. The clinical data recorded at implantation and 36 months included probing depth, bleeding on probing, presence of plaque, and a radiological evaluation. For descriptive analyses, mean values and standard deviations (SD) were calculated. Linear mixed‐effects models with patient as a random effect were applied ( <jats:italic>α</jats:italic> = 0.05), correcting for multiple comparisons, to analyze the evolution of peri‐implant parameters. Results Twenty‐four patients with a mean age 70.8 years (SD 8.0) with bilateral mandibular free‐end situations received 48 short dental implants (6 mm length). One implant failure was reported, resulting in a 97.9% survival rate [95% CI: 93.9–100] over a mean follow‐up of 4.2 years (SD 1.1). Implant success (ICOI Criteria) was 80.1% [95% CI: 66.9–93.3]. Probing depths remained stable from baseline to 36‐month follow‐up: 2.55 mm (SD 1.19) vs. 2.58 mm (SD 1.19), <jats:italic>p</jats:italic> &gt; 0.05. Mean marginal bone loss was 1.08 mm. Plaque accumulation increased significantly ( <jats:italic>p</jats:italic> &lt; 0.001). Keratinized mucosa was present at all sites at the 3‐year follow‐up. Conclusions Strategic placement of 6 mm short dental implants represents a viable treatment option for converting Kennedy Class I RPDs into implant‐assisted RPDs, with high survival rates and stable peri‐implant parameters in the 3‐year follow‐up.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"52 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149130371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Adjunctive Use of MSC Secretome for Guided Bone Regeneration: An Experimental In Vivo Investigation","authors":"Siddharth Shanbhag,&nbsp;Javier Sanz-Esporrin,&nbsp;Javier Nuñez,&nbsp;Fernando Luengo,&nbsp;Manuel Toledano-Osorio,&nbsp;Carina Kampleitner,&nbsp;Patrick Heimel,&nbsp;Barbara Schædl,&nbsp;F. Javier Vela Gonzalez,&nbsp;Samih Mohamed-Ahmed,&nbsp;Cecilie Gjerde,&nbsp;Reinhard Gruber,&nbsp;Kamal Mustafa,&nbsp;Mariano Sanz","doi":"10.1111/clr.70164","DOIUrl":"10.1111/clr.70164","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate the efficacy of mesenchymal stromal cells' (MSC) secretome delivered as conditioned media (CM) as an adjunct to a xenograft (XG) and collagen membrane (MEM) for guided bone regeneration (GBR) in chronic non-contained mandibular defects in minipigs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Chronic bilateral mandibular defects were surgically created in seven minipigs. In a split-mouth design, defects were treated with either CM-functionalized (test) or native XG + MEM (control) and evaluated after 4 and 12 weeks. New bone formation was assessed using in vivo computed tomography (CT) and ex vivo micro-CT, histology and immunohistochemistry (IHC). Quantitative CT, micro-CT and histomorphometric data were statistically analysed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>No significant differences in new bone formation were observed between the test and control group at either timepoint. These findings could be partly explained by a high intrinsic healing capacity and continual growth of the animals. Minimal residual XG material was detected in both groups at 4 and 12 weeks. When present, these remnants were associated with multinucleated Cathepsin K-positive cells (IHC) with no observable differences between the groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The adjunctive use of MSC secretome in combination with XG and MEM did not improve GBR outcomes in chronic non-contained mandibular defects in the present minipig model. The suitability of this animal model for experimental GBR may be questionable.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 10","pages":"1217-1229"},"PeriodicalIF":5.9,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148663500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Nomogram for Predicting Buccal Bone Coverage at the Implant Shoulder in Bone Augmentation Using the Full-Thickness Envelope Flap Technique: A Retrospective Cohort Study","authors":"Xirui Zhang,&nbsp;Jiayu Gao,&nbsp;Tiantian Yu,&nbsp;Quan Yuan,&nbsp;Xingmei Yang","doi":"10.1111/clr.70156","DOIUrl":"10.1111/clr.70156","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To identify the predictors, develop and validate a nomogram for implant buccal shoulder dehiscence following horizontal bone augmentation using the full-thickness envelope flap technique (FEFT).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A total of 318 implants in 250 patients receiving FEFT were included in the study. Implants were classified as “buccal shoulder dehiscence” or “buccal shoulder coverage” based on radiographic images obtained at 6 months postoperatively. Predictive factors for buccal shoulder dehiscence were evaluated using regression analysis. A nomogram was constructed, and model performance was assessed through calibration and discrimination analyses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Six factors were identified as predictors: initial deficit depth, graft overhanging angle, bone graft contour relative to the bone arch, type of bone substitute material, implant bucco-lingual position with respect to the initial alveolar bone profile, and implant site. The model showed an apparent area under the curve (AUC) of 0.899. This performance remained robust after patient-level cluster bootstrap validation (mean AUC = 0.886). The model demonstrated acceptable calibration, and decision curve analysis confirmed net clinical benefit.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This nomogram provides a practical tool for predicting buccal shoulder coverage at 6 months after implant placement with simultaneous FEFT.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p><b>Trial Registration:</b> The study protocol was registered at the Chinese Clinical Trial Registry (ChiCTR2500115545)</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 10","pages":"1145-1157"},"PeriodicalIF":5.9,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148428750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Segmented Intraoral Scanning With a Palatal Marker for Complete-Arch Digital Implant Impressions: An In Vitro Comparative Study","authors":"Reo Ikumi,&nbsp;Takahiro Murakami,&nbsp;Luís Azevedo,&nbsp;João Pitta,&nbsp;Duygu Karasan,&nbsp;Irena Sailer","doi":"10.1111/clr.70161","DOIUrl":"10.1111/clr.70161","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To compare four complete-arch implant impression workflows—segmented right/left IOS merged via a palatal marker (IOS-LEGO-Seg), continuous full-arch IOS with a palatal marker (IOS-LEGO-Full), continuous full-arch IOS without a palatal marker (IOS-Full), and a conventional open-tray PVS impression followed by cast fabrication and cast scanning (CI)—and to evaluate whether segmentation combined with a palatal marker improves agreement with a laboratory reference dataset in a maxillary edentulous model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A maxillary edentulous dental cast with six implants was used to compare IOS-LEGO-Seg, IOS-LEGO-Full, IOS-Full, and CI. Intraoral scans were acquired, with 10 repetitions per condition. Datasets were superimposed onto a master reference scan using three alveolar-ridge markers; the palatal marker was excluded. The primary outcome was the concordance rate, defined as the proportion of intraoral scan body surface points within ±50 μm of the reference. A linear mixed-effects model was used to compare workflows (<i>α</i> = 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>IOS-LEGO-Seg achieved the highest concordance, followed by IOS-LEGO-Full, IOS-Full, and CI (<i>p</i> &lt; 0.001). The concordance rate was comparable between the IOS-LEGO-Full and IOS-Full groups, indicating that the addition of a palatal marker alone did not improve accuracy. Site-specific analysis revealed lower concordance at the distal molars (#16 and #26) in the non-segmented IOS workflows; however, this effect was mitigated by the segmented approach. The CI group did not show site-specific differences.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The segmented workflow with a palatal marker may represent an accessible strategy for improving the accuracy of maxillary complete-arch implant impressions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 10","pages":"1208-1216"},"PeriodicalIF":5.9,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70161","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148595568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}