Clinical Oral Implants Research最新文献_第2页

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IF 5.3 1区医学

Clinical Oral Implants Research Pub Date : 2025-09-10 DOI: 10.1111/clr.70043

引用次数: 0

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IF 5.3 1区医学

Clinical Oral Implants Research Pub Date : 2025-09-10 DOI: 10.1111/clr.70042

引用次数: 0

Role of Local Factors on the Occurrence of Peri-Implantitis: A Cross-Sectional Analysis. 局部因素在种植体周围炎发生中的作用：横断面分析。

IF 4.3 1区医学

Clinical Oral Implants Research Pub Date : 2025-09-08 DOI: 10.1111/clr.70036

Alberto Monje,Ramon Pons,Maria Costanza Soldini,Paul S Rosen,José Nart,Daniel Buser

{"title":"Role of Local Factors on the Occurrence of Peri-Implantitis: A Cross-Sectional Analysis.","authors":"Alberto Monje,Ramon Pons,Maria Costanza Soldini,Paul S Rosen,José Nart,Daniel Buser","doi":"10.1111/clr.70036","DOIUrl":"https://doi.org/10.1111/clr.70036","url":null,"abstract":"OBJECTIVEA cross-sectional study was made to evaluate the role of local factors, including surgical, implant, and prosthesis-related parameters, in the presence of peri-implantitis.METHODSConsecutive partially edentulous patients with ≥ 1 implant presenting peri-implantitis were included. Clinical and radiographic data were collected to characterize local factors. Overall, 28 site-specific variables were analyzed for peri-implantitis and non-peri-implantitis implants. Simple and multiple logistic regression analyses were performed to explore potential associations. The diagnostic accuracy of those variables that demonstrated statistical significance in the multiple logistic regression analysis was further tested.RESULTSIn total, 100 patients with 452 implants met the inclusion criteria. Of these, 227 implants (50.2%) were diagnosed with peri-implantitis, while 225 (49.8%) did not present peri-implantitis. The multiple logistic regression analysis demonstrated statistical significance for the following factors: (1) medial implant position within the prosthesis (OR = 3.9) was more prone to develop peri-implantitis; (2) internal Morse taper implant connection was the least likely to develop peri-implantitis (OR = 0.43); (3) mesio-distally centered implants were less prone to exhibit peri-implantitis (OR = 0.46); (4) bucco-lingual centered implants were less prone to exhibit peri-implantitis (OR = 0.29); (5) implants positioned inside (≥ 2 mm) the bony housing were less prone to exhibit peri-implantitis (OR = 0.13); and (6) implants tilted 10°-30° (OR = 5.84) and ≥ 30° (OR = 7.43) were more prone to exhibit peri-implantitis. Moreover, a prediction model based on the aforementioned factors yielded a high level of accuracy.CONCLUSIONSImplant malpositioning is a critical factor associated with peri-implantitis.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"11 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Statistical Gems and Cautions From the Statistical Advisory Board of Clinical Oral Implants Research. 临床口腔种植体研究统计顾问委员会的统计瑰宝和注意事项。

IF 4.3 1区医学

Clinical Oral Implants Research Pub Date : 2025-09-04 DOI: 10.1111/clr.70033

Cláudio Mendes Pannuti,Hélio Doyle Pereira da Silva,Naichuan Su,Kar Yan Li,Lisa J A Heitz-Mayfield

{"title":"Statistical Gems and Cautions From the Statistical Advisory Board of Clinical Oral Implants Research.","authors":"Cláudio Mendes Pannuti,Hélio Doyle Pereira da Silva,Naichuan Su,Kar Yan Li,Lisa J A Heitz-Mayfield","doi":"10.1111/clr.70033","DOIUrl":"https://doi.org/10.1111/clr.70033","url":null,"abstract":"OBJECTIVEStatistics is fundamental in implant dentistry research, playing a crucial role in study design, data analysis, and interpretation of findings. This editorial, authored by members of the Statistical Advisory Board of Clinical Oral Implants Research, aims to highlight common statistical pitfalls encountered in submitted manuscripts and provide practical recommendations to enhance the quality of statistical reporting.MATERIALS AND METHODSIn this editorial, study design considerations, sample size calculation, appropriate selection of statistical tests, multiplicity issues, handling hierarchical data structures, and best practices for data presentation are discussed. The importance of pre-registering research protocols, adhering to pre-specified analyses, and reporting effect sizes alongside p-values is emphasised. Additionally, common misinterpretations of statistical significance and the risks of extrapolating findings beyond their intended scope are addressed.RESULTSStatistical errors remain prevalent in the scientific literature, affecting the validity of results and evidence-based decision making.CONCLUSIONSBy following guidelines, authors can improve the robustness and reproducibility of their research, ultimately contributing to higher-quality evidence in implant dentistry. Guidance for researchers, reviewers, and readers in handling statistical challenges is presented aiming to ensure that studies published in Clinical Oral Implants Research meet the highest methodological standards.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"71 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144995885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Odanacatib Coating Supports Osseointegration of Implants: A Preclinical Study. Odanacatib涂层支持种植体骨整合：临床前研究。

IF 4.3 1区医学

Clinical Oral Implants Research Pub Date : 2025-09-04 DOI: 10.1111/clr.70038

Natália Dos Santos Sanches,Caroline Liberato Marchiolli,Lara Cristina Cunha Cervantes,Maria Cristina Ruiz Voms Stein,Sara Alves Berton,Estéfany Lopes Lemes do Prado,Carina Kampleitner,Francisley Ávila Souza,Roberta Okamoto,Reinhard Gruber,Idelmo Rangel Garcia Júnior

{"title":"Odanacatib Coating Supports Osseointegration of Implants: A Preclinical Study.","authors":"Natália Dos Santos Sanches,Caroline Liberato Marchiolli,Lara Cristina Cunha Cervantes,Maria Cristina Ruiz Voms Stein,Sara Alves Berton,Estéfany Lopes Lemes do Prado,Carina Kampleitner,Francisley Ávila Souza,Roberta Okamoto,Reinhard Gruber,Idelmo Rangel Garcia Júnior","doi":"10.1111/clr.70038","DOIUrl":"https://doi.org/10.1111/clr.70038","url":null,"abstract":"INTRODUCTIONOdanacatib (ODN), a cathepsin K inhibitor, is a drug that reduces bone resorption while preserving bone formation. ODN was initially developed for the treatment of postmenopausal osteoporosis, but further development as a systemic medication has been discontinued. Here, we propose ODN as a topical treatment, the coating of dental implants, to achieve an anabolic shift of early osseointegration.MATERIAL AND METHODSTo this aim, we have coated double acid etching titanium implants (SLA) with and without ODN dispersed in a simulated body fluid (SBF). The implants were inserted into the tibia of 72 male Wistar rats and osseointegration was studied on Days 15 and 40. Biomechanical testing, micro-computed microtomography, and histomorphometric analyses were performed.RESULTSBiomechanical testing reveals that after 15 days of healing, removal torque increased from 2.5 Ncm (1.5-4.4) to 3.9 Ncm (1.7-7.6) when comparing SBF alone with SBF containing ODN, respectively (p = 0.017). Consistently, micro-computed microtomography indicated that local bone volume increased from 24.4% (13.86-32.45) to 32.8% (19.7-39.4), respectively (p = 0.003). The same was true for presumed bone-to-implant contact, which was 34.38% (27.0-50.0) and 43.33% (31.6-54.2), respectively (p = 0.035). Histomorphometric analyses confirmed that the new bone area per total area increased from 34.78% (18.9-43.7) to 41.10% (23.5-54.0), respectively (p = 0.102). This trend proceeds after 40 days of osseointegration.DISCUSSIONThese findings suggest that topical delivery of a cathepsin K inhibitor can support the early osseointegration phase in an ectopic rodent implantation model.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"49 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144995877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-Term Evaluation of Narrow-Diameter Dental Implants in Posterior Sites in Patients With History of Periodontitis: A Retrospective Study With an 11.5-Year Mean Follow-Up. 对有牙周炎病史的患者进行后牙狭窄直径种植体的长期评价：一项平均随访11.5年的回顾性研究。

IF 5.3 1区医学

Clinical Oral Implants Research Pub Date : 2025-09-03 DOI: 10.1111/clr.70028

Maria Costanza Soldini, Isabel Arroyo, Riccardo Peragine, Enrique Roldán, Cristina Valles, Ramón Pons

{"title":"Long-Term Evaluation of Narrow-Diameter Dental Implants in Posterior Sites in Patients With History of Periodontitis: A Retrospective Study With an 11.5-Year Mean Follow-Up.","authors":"Maria Costanza Soldini, Isabel Arroyo, Riccardo Peragine, Enrique Roldán, Cristina Valles, Ramón Pons","doi":"10.1111/clr.70028","DOIUrl":"10.1111/clr.70028","url":null,"abstract":"Aim: To assess the factors influencing the survival and success rates of narrow diameter implants (NDIs) placed in the posterior area; additionally, the study evaluated marginal bone changes, along with biological and prosthetic complications.Materials and methods: This retrospective single-center study investigated the clinical and radiographic outcomes of 227 NDIs placed in the premolar and molar regions of 119 patients. The analysis focused on implant survival and success rates, marginal bone levels (MBL), and the incidence of biological and mechanical complications. Generalized estimating equations (GEE) were employed to assess the impact of patient- and implant-related characteristics on these outcomes.Results: Over a mean follow-up period of 11.51 years (SD: 4.03) the study recorded the loss of 12 NDIs in seven patients. The Kaplan-Meier survival rates were 90.3% (95% CI: 85.4%-95.4%) and 85.7% (95% CI: 77.2%-95.0%) respectively. The average marginal bone loss (MBL) was estimated at -0.75 (SD 1.34) mm. Mucositis was observed in 33.18% of the implants and peri-implantitis in 9.86% of the sample.Conclusion: This study offers valuable understanding of NDIs as a predictable option in implant dentistry, particularly for patients with challenging anatomical conditions. However, careful case selection and comprehensive treatment planning are crucial to minimize the risk of implant fractures.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dental Implants in Medically Compromised Patients Undergoing or After Receiving Anti‐Resorptive or Radiotherapy: Retrospective Clinical and Radiographic Data 在接受抗吸收或放疗的医学受损患者中种植牙：回顾性临床和放射学数据

IF 4.3 1区医学

Clinical Oral Implants Research Pub Date : 2025-09-03 DOI: 10.1111/clr.70040

Christian Mertens, Fabian Staudinger, Maximilian Smielowski, Thomas Rückschloss, Gregor Schnug, Jürgen Hoffmann, Oliver Ristow

{"title":"Dental Implants in Medically Compromised Patients Undergoing or After Receiving Anti‐Resorptive or Radiotherapy: Retrospective Clinical and Radiographic Data","authors":"Christian Mertens, Fabian Staudinger, Maximilian Smielowski, Thomas Rückschloss, Gregor Schnug, Jürgen Hoffmann, Oliver Ristow","doi":"10.1111/clr.70040","DOIUrl":"https://doi.org/10.1111/clr.70040","url":null,"abstract":"Objective and AimA retrospective study to evaluate the clinical and radiological outcomes of dental implants placed in compromised patients who have undergone antiresorptive therapy (AR) or head and neck radiotherapy (IR).Material and MethodsDental implant placement was evaluated in compromised patients undergoing or after receiving AR/IR therapy following specific preventive measures: antibiotic prophylaxis (2 days before and 5 days after surgery) and primary wound closure with submerged healing for 4 months. The primary outcome was implant survival during the observation period. Secondary outcomes included marginal bone loss, occurrence of osteonecrosis, and factors influencing implant survival.ResultsA total of 92 patients (59 IR, 32 AR) with 369 dental implants were included in the study. During a mean follow‐up period of 25 months (SD: 16), 23 implants were lost (IR: 21, AR: 2). Implant survival rates were 92% and 98% for IR and AR, respectively. Identified risk factors for implant failure included placement in neomandibular/−maxillary sites, maxillary implantation, implant diameter < 4.2 mm, active smoking, and diabetes mellitus. The mean marginal bone loss was 0.57 mm (SD: 1.51) in the IR group and −0.09 mm (SD: 1.17) in the AR group.ConclusionWith comprehensive risk assessment and careful evaluation of implant indications, dental implants can serve as an effective dental rehabilitation option for patients undergoing or after receiving AR/IR therapy, provided strict adherence to preventive measures is maintained. Implants placed following AR therapy demonstrate higher survival rates and reduced marginal bone loss compared to those placed after IR therapy.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"31 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to “Effectiveness of Restoration Strategies for Posterior Missing Teeth With Dental Implants: A Retrospective Study” 对“后牙缺失种植体修复策略的有效性：回顾性研究”的更正

IF 5.3 1区医学

Clinical Oral Implants Research Pub Date : 2025-08-31 DOI: 10.1111/clr.70039

引用次数: 0

Peri‐Implant Conditions During Supportive Periodontal Care: A Prospective Study 支持牙周护理期间种植体周围状况：一项前瞻性研究

IF 4.3 1区医学

Clinical Oral Implants Research Pub Date : 2025-08-28 DOI: 10.1111/clr.70026

Margherita Sforza, Pasquale Santamaria, Aliye Akcalı, Luigi Nibali

{"title":"Peri‐Implant Conditions During Supportive Periodontal Care: A Prospective Study","authors":"Margherita Sforza, Pasquale Santamaria, Aliye Akcalı, Luigi Nibali","doi":"10.1111/clr.70026","DOIUrl":"https://doi.org/10.1111/clr.70026","url":null,"abstract":"AimTo assess peri‐implant conditions in a cohort of patients previously treated for periodontitis undergoing supportive periodontal care (SPC).Materials and MethodsA prospective observational study was carried out on previously treated periodontitis patients followed for 5 years in SPC. Peri‐implant diagnosis at baseline and the end of the 5‐year period was assessed.ResultsTwo hundred patients were included in the study. A total of 88 implants were present at baseline in 31 of those patients. A total of 55 (62.5%) implants were diagnosed as having healthy peri‐implant tissues, while 22 (25%) were diagnosed with peri‐implant mucositis and 11 (12.5%) with peri‐implantitis. Five‐year data are available for 68 implants in 23 patients. None of these implants was lost during the 5 years follow‐up. An additional 20 implants were placed during the study period, resulting in a total of 88 implants reassessed at the last study follow‐up, with peri‐implant diagnosis almost unchanged compared with baseline. None of the studied patient and implant factors were associated with implant diagnosis in a multilevel model with logistic regression target distribution.ConclusionsA small percentage of implants in a population undergoing SPC were diagnosed with peri‐implantitis, and peri‐implant conditions were maintained almost unchanged during 5 years of SPC.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"120 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144910958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Trends in the Prevention of Peri‐Implantitis: Spanish Society of Periodontology (SEPA) Foundation Survey Using the Delphi Method 预防种植周炎的临床趋势：西班牙牙周病学会（SEPA）基金会使用德尔菲法进行调查

IF 4.3 1区医学

Clinical Oral Implants Research Pub Date : 2025-08-28 DOI: 10.1111/clr.70030

Alberto Monje, Ana Molina, Olalla Argibay, Beatriz de Tapia, Jan Derks, Elena Figuero, Adrián Guerrero, Fernando Luengo, Eduardo Montero, Ignacio Sanz‐Martín, Ignacio Sanz‐Sánchez, Cristina Vallés, José Nart

{"title":"Clinical Trends in the Prevention of Peri‐Implantitis: Spanish Society of Periodontology (SEPA) Foundation Survey Using the Delphi Method","authors":"Alberto Monje, Ana Molina, Olalla Argibay, Beatriz de Tapia, Jan Derks, Elena Figuero, Adrián Guerrero, Fernando Luengo, Eduardo Montero, Ignacio Sanz‐Martín, Ignacio Sanz‐Sánchez, Cristina Vallés, José Nart","doi":"10.1111/clr.70030","DOIUrl":"https://doi.org/10.1111/clr.70030","url":null,"abstract":"ObjectiveTo assess clinical trends to prevent peri‐implantitis in applying a two‐step survey based on the Delphi method.Material and MethodsA panel of participants aged < 45 years old selected by the Spanish Society of Periodontology (SEPA) was asked to answer a survey with 75 statements prepared by a steering committee. Items were divided into 5 major areas: etiopathogenesis and epidemiology, surgical, implant, and prosthetic‐related factors on the onset/progression of peri‐implantitis, and self‐ and professional‐administered oral hygiene. Degree of agreement or disagreement among participants was reported.ResultsIn total, 44 participants responded favorably to participate in the survey. From the 75 statements formulated, 35 were agreed on in a first round (46.7%). From the 40 statements that did not reach consensus, 16 were agreed on in a second round (40.0%). Overall, 51 out of 75 statements (68.0%) achieved consensus in a second round. From these, 36 (48.0%) were in agreement, while 15 (20.0%) were in disagreement. The sections that explored surgical‐related factors and prosthesis‐related factors of peri‐implantitis yielded the highest level of conflict (9/18 and 8/14 statements demonstrated indeterminate agreement, respectively). In the sections on the etiopathogenesis and epidemiology of peri‐implantitis and implant‐related factors, most items reached consensus (14/17 and 10/13 items, respectively). The section on self‐ and professional‐administered oral hygiene obtained the highest level of consensus, with only 1/13 items showing dissent among the participants.ConclusionThe results of this study on the clinical trends in the prevention of peri‐implantitis showed consensus agreement for ∼70% of the statements evaluated.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"11 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144915363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0