Clinical Oral Implants Research最新文献

{"title":"Clinical Effects of Angulated Single-Implant Crowns With Different Retention Methods in the Aesthetic Area: A Retrospective Cohort Study With 12-24 Months Follow-Up.","authors":"Xiaying Ding,Yudi Wang,Manhou Choi,Hao Chen,Mengfei Yu,Yu Wang","doi":"10.1111/clr.70128","DOIUrl":"https://doi.org/10.1111/clr.70128","url":null,"abstract":"OBJECTIVEThe objective of this study is to evaluate the clinical efficacy of angulated single-implant crowns using the hybrid retention versus pure screw-retained restorations in the aesthetic area.MATERIALS AND METHODSA retrospective study design was adopted. Patients were included and divided into two groups according to the abutment types they had used: the hybrid retention (AS) and screw-retained retention (ASC). Implant survival rate, mechanical complications, bleeding on probing proportion, probing depth, plaque index, Jemt papillary index, marginal displacement, pink/white esthetic score (PES/WES), emergence angle, marginal bone loss (MBL), and buccal bone thickness (BBT) resorption were evaluated.RESULTS43 patients were included (AS: 22, ASC: 21). The average follow-up was 16.88 months. No cases of implant failure were observed. Mechanical complications were observed in 31.82% of the AS group and 9.52% of the ASC group (p > 0.05). The MBL showed no significant difference (p > 0.05). The BBT resorption was significantly higher in the ASC group than the AS group (p < 0.05). The PES was statistically higher in the AS group than the ASC group (p < 0.01). No other significant difference was observed.CONCLUSIONBoth AS and ASC abutments achieved acceptable clinical short-term outcomes for maxillary anterior implant restorations, with 100% observed implant survival rates and no statistically significant differences in survival or peri-implant bone level stability. The AS group exhibited potential advantages in soft-tissue contour and buccal bone thickness preservation. Although the incidence of mechanical complications was higher in the AS group clinically, the difference did not reach statistical significance, warranting further validation.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"6 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147630350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Accuracy of Deep Learning Models in Detecting Peri-Implant Marginal Bone Loss: A Systematic Review and Meta-Analysis","authors":"Momen A. Atieh,&nbsp;Maanas Shah,&nbsp;Abeer Hakam,&nbsp;Fawaghi AlAli,&nbsp;Samhar AlSayed,&nbsp;Andrew Tawse-Smith,&nbsp;Nabeel H. M. Alsabeeha","doi":"10.1111/clr.70090","DOIUrl":"10.1111/clr.70090","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Peri-implantitis is a common implant complication requiring early detection to prevent bone loss and implant failure. Deep learning models show promise for enhancing radiographic diagnosis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This review systematically evaluated the diagnostic performance of deep learning models in detecting peri-implant marginal bone loss on radiographic images.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A comprehensive search of PubMed, EMBASE, CENTRAL, ClinicalTrials.gov, and ProQuest identified studies published between 2010 and July 2025. Two reviewers independently screened studies, extracted data, and assessed methodological quality using QUADAS-2. Diagnostic metrics, including sensitivity, specificity, F1-score, area under the curve (AUC), were synthesized using random-effects meta-analysis. Heterogeneity and publication bias were evaluated using <i>I</i>² statistics, meta-regression, and funnel plots.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Five studies comprising 12,545 periapical and panoramic radiographs met inclusion criteria. Deep learning models achieved pooled sensitivity of 88%, specificity of 91%, and AUC of 0.95, indicating high diagnostic performance. Positive and negative likelihood ratios suggested strong clinical utility. Quality was generally good, though reporting of implant characteristics and data augmentation was inconsistent. Meta-regression revealed that dataset size and unit of analysis influenced accuracy, whereas imaging type did not. No publication bias was found.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Deep learning models demonstrate high accuracy in detecting radiographic marginal bone loss, potentially indicating peri-implantitis but cannot substitute for comprehensive clinical assessment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Relevance</h3>\u0000 \u0000 <p>These models offer a promising adjunct for radiographic detection of marginal bone loss, supporting clinicians in early diagnosis and timely interventions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 4","pages":"385-401"},"PeriodicalIF":5.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70090","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146005337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Connective Tissue Graft as an Adjunct to Guided Bone Regeneration in the Surgical Treatment of Peri-Implantitis: A Dual-Center Randomized Controlled Trial","authors":"Lucrezia Paterno Holtzman,&nbsp;Iva Milinkovic,&nbsp;Marija Vuckovic,&nbsp;Chiara Malpassi,&nbsp;Marla Cuppini,&nbsp;Alex Solderer,&nbsp;Zoran Aleksic,&nbsp;Luca Cordaro","doi":"10.1111/clr.70093","DOIUrl":"10.1111/clr.70093","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate whether adding a connective tissue graft (CTG) to guided bone regeneration (GBR) improves clinical and radiographic outcomes in surgical peri-implantitis treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Thirty-two patients with peri-implantitis were randomly assigned to receive GBR and CTG (test group, TG) or GBR alone (control group, CG). Clinical and radiographic parameters were recorded at baseline, 6, and 12 months. The primary outcome was the change in clinical attachment level (CAL), while secondary outcomes included pocket probing depth (PPD), bleeding on probing (BoP), plaque index (PI), keratinized mucosa width (KMW), mucosal thickness (MT), recession (REC), suppuration (SUP), marginal bone levels (MBL), bone defect morphology, and disease resolution (DR).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>At 12 months, CAL gain was significantly higher in TG compared with CG (3.21 ± 1.57 mm vs. 1.65 ± 1.28 mm; <i>p</i> = 0.022), and TG achieved significantly greater increase in KMW (2.25 ± 2.89 mm vs. 0.26 ± 1.49 mm; <i>p</i> = 0.010). Both groups showed significant PPD reduction, with a greater, though not statistically significant, improvement comparing TG with CG (3.25 ± 1.59 mm vs. 1.97 ± 1.23 mm; <i>p</i> = 0.052). Additionally, MBL improved significantly in both groups (<i>p</i> &lt; 0.001), with higher gains in TG (<i>p</i> &lt; 0.001). However, DR was comparable between the two groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>GBR effectively improves peri-implant parameters after 1 year. Adding a CTG enhances CAL and KMW gains and may promote more favorable bone levels, although the impact on DR remains inconclusive. Long-term studies are warranted to confirm these findings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>ClinicalTrials.gov NCT04323540</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 4","pages":"478-495"},"PeriodicalIF":5.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70093","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146089133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary Experiences and Needs of Edentulous Patients Following Full Arch Implant Surgery: A Qualitative Study","authors":"Xinxin Han,&nbsp;Qian Deng,&nbsp;Qian Ding,&nbsp;Yajin Li,&nbsp;Shaoxia Pan","doi":"10.1111/clr.70092","DOIUrl":"10.1111/clr.70092","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>This study aimed to explore the dietary experiences and needs of edentulous patients after full arch implant surgery, and to provide evidence for developing scientific dietary management protocols.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A descriptive qualitative study guided by phenomenological principles was conducted by using purposive sampling. Semi-structured in-depth interviews were performed with participants who underwent full arch implant surgery in edentulous jaws. The data were analyzed using thematic analysis, involving familiarizing oneself with the data, generating initial codes, identifying, reviewing, defining, and naming themes, and producing the report.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-one participants, mean age (61.05 ± 7.05) years, were invited and included in the study. Three main themes and nine sub-themes were identified: Functional food intake limitation (changes in food texture, masticatory dysfunction, limited dietary diversity, decreased food intake); Decline in quality of life (loss of eating enjoyment, excessive dietary restrictions, invisible impairment of social functioning); Need for dietary guidance (urgent demand for professional guidance, content of the requirements and formal preference).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Edentulous patients undergoing implant surgery experienced multidimensional eating restrictions and dietary challenges. The majority of patients expressed a pressing need for professional dietary guidance to enhance dietary experience and quality of life. During the critical period of osseointegration following edentulous jaw surgery, a combination of conventional and digital methods can be employed to meet patients' information needs and address existing clinical shortcomings. Based on research findings, future efforts are needed to develop a phased progressive dietary guidance protocol tailored to patient needs, aligned with the biological stages of osseointegration.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 4","pages":"468-477"},"PeriodicalIF":5.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146098413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peri-Implant Crevicular Fluid Analysis by Mid-Infrared Spectroscopy in Peri-Implantitis—A Pilot Study","authors":"Francisco Maligno,&nbsp;Ricardo N. M. J. Páscoa,&nbsp;Pedro S. Gomes","doi":"10.1111/clr.70091","DOIUrl":"10.1111/clr.70091","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to assess biochemical differences in peri-implant crevicular fluid (PICF) using ATR-FTIR spectroscopy and multivariate analysis, through a between-participant comparison of healthy and peri-implantitis (PI) sites, and a within-participant comparison of PI-PICF and GCF from contralateral periodontal healthy teeth.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Samples were categorized into three groups based on peri-implant status and sampling site: PICF from peri-implant healthy sites, PICF from PI-affected sites, and GCF from contralateral healthy teeth in PI patients, with <i>n</i> = 20/group. Samples were collected and analyzed through ATR-FTIR spectroscopy. Chemometric models were applied for cluster/outlier identification and discrimination. Regression coefficient vectors of PLS-DA models identified key spectral differences between groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 40 implants were analyzed; participants had a mean age of 62 years, predominantly female (59%), non-smokers (88%), and most received regular maintenance therapy (82%). PCA revealed subtle cluster formations without clear group separation. Comparing PICF from patients with and without PI, the most important wavenumbers for the PLS-DA model were within 1700–1680 cm⁻¹, 1190–1130 cm⁻¹, and 1050–980 cm⁻¹, associated with protein-related signals and nucleic-acid content. Comparing the GCF and PICF from PI patients, using a split-mouth design, the most important wavenumbers were 3006 cm⁻¹, 2982 cm⁻¹, and 2900 cm⁻¹, related to lipid structures. In terms of accuracy, between-participant assessment achieved 75%, whereas the split-mouth assessment reached 83.4%.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>FTIR-spectroscopy combined with chemometric modeling effectively discriminates peri-implant health and PI in both inter- and intra-subject comparisons. Higher within-subject accuracy supports FTIR's potential as a site-specific, non-invasive diagnostic tool for peri-implantitis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 4","pages":"453-467"},"PeriodicalIF":5.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70091","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146021338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Abutment Shape on Implant Marginal Bone Remodeling: A Double-Blind, Randomized 24-Month Clinical Study","authors":"Flavio Seijas Naya,&nbsp;Juan C. Bernabeu Mira,&nbsp;Alba Pérez Jardón,&nbsp;Mercedes Conde Amboage,&nbsp;David Peñarrocha Oltra,&nbsp;Fabio Camacho Alonso,&nbsp;Mario Pérez Sayáns","doi":"10.1111/clr.70085","DOIUrl":"10.1111/clr.70085","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study follows a 2-year evaluation to verify marginal bone remodeling (MBR) trends associated with different abutment designs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A balanced, randomised, double-blind clinical trial with two parallel experimental arms. 68 implants were placed in 9 men and 12 women, 48.5% using the straight abutment and 51.5% the concave abutment. The primary variable was peri-implant tissue stability, measured by marginal bone loss (MBL) or gain (MBG) through digital radiology. Mixed linear regression models and Additive Generalized Additive Models were constructed to estimate MBR, simultaneously considering the variables abutment height, group, and time.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>At 24 months, linear mixed-effects regression models revealed that the concave abutment group exhibited significantly less MBL than the straight abutment group across mesial, distal, and average measurements (<i>p</i> = 0.006–0.026). Significant interactions between abutment type and time at 8 weeks and 6 months suggest early and sustained benefits of the concave design. At 24 months, this effect remained significant except in the mesial model (<i>p</i> = 0.072). Abutment height was positively associated with MBL, particularly in the straight group; however, in the concave group, greater height mitigated bone loss (<i>p</i> &lt; 0.01).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Concave abutments demonstrated a potential advantage in reducing early marginal bone loss and promoting mid-term bone stability compared to straight abutments. Their design may enhance soft tissue adaptation, contributing to improved peri-implant bone preservation. While increased abutment height showed a protective effect in the concave group, these findings require confirmation. Further long-term studies are warranted to validate these results and clarify their clinical relevance.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 4","pages":"402-412"},"PeriodicalIF":5.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145854929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunohistological Evaluation of Peri-Implant Soft Tissue Grafting Using a Porcine Dermal Matrix—A Human Histological Study","authors":"F. R. S. Michallek,&nbsp;M. Sluka,&nbsp;V. C. Landwehr,&nbsp;K. Vach,&nbsp;L. Larsson,&nbsp;K. Nelson,&nbsp;S. Nahles,&nbsp;F. Kernen,&nbsp;G. Iglhaut,&nbsp;T. Fretwurst","doi":"10.1111/clr.70088","DOIUrl":"10.1111/clr.70088","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The aim was the immunohistological evaluation of a porcine dermal matrix (PDM) in comparison to a non-augmented control group for peri-implant tissue thickening.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>This human histological study involved the placement of PDM in the test group (20 patients) during implant placement, while the control group underwent implant placement without grafting (20 patients). Postoperative clinical evaluations were conducted, and biopsies were obtained after 3 months. Histomorphometric evaluation utilized H&amp;E staining. Immunohistological analysis included CD31, PSR, TE-7, CD3, CD20, CD138, and CD68.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 40 patients (17 females, 23 males; 60.62 years) were included. Though more frequent gingival redness occurred during wound healing in the PDM, the groups showed no significant differences in epithelial thickness (<i>p</i> = 0.63), rete ridges (<i>p</i> = 0.53), papilla density (<i>p</i> = 0.626), papilla complexity (<i>p</i> = 0.053), vascularization (<i>p</i> = 0.052), connective tissue morphology (<i>p</i> = 0.127), collagen differentiation (<i>p</i> = 0.41), and CD3⁺ (<i>p</i> = 0.85) and CD138⁺ cells (<i>p</i> = 0.33). The PDM group showed significantly more CD68⁺ cells (<i>p</i> = 0.049) and CD20⁺ cells (<i>p</i> = 0.046), which correlates with a potentially distinct immune response caused by the PDM.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The PDM used in this study exhibited no significant differences regarding epithelial changes, vascularization, tissue morphology, and collagen differentiation compared to a healthy control sample 3 months after grafting. The PDM group demonstrated a significantly higher frequency of CD68⁺ and CD20⁺ cells. The noticeable interindividual variation in immunoprofiles and clinical relevance of these findings should be investigated in future research.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 4","pages":"426-438"},"PeriodicalIF":5.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70088","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146073326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-Year Analysis of Clinical and Radiological Outcomes of Two-Piece Zirconia Compared to Titanium Implants: A Multicenter Prospective Randomized Clinical Trial","authors":"Marc Balmer,&nbsp;Michael Payer,&nbsp;Anke Steinwender,&nbsp;Valentin Herber,&nbsp;Ronald E. Jung,&nbsp;Sebastian Kühl","doi":"10.1111/clr.70094","DOIUrl":"10.1111/clr.70094","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the clinical performance of two-piece zirconia implants with screw-retained abutments compared to titanium implants after 1 year of loading.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>In this multicenter, prospective, randomized clinical trial, 61 two-piece zirconia and 61 titanium implants were placed and restored with single crowns. Evaluations were performed at implant placement, crown delivery, and 1-year post-loading. Peri-implant Marginal Bone Loss (MBL), survival rate, early wound healing index, and soft tissue parameters were assessed. Intergroup comparisons of continuous outcomes were performed using Linear Mixed-Effects Models accounting for center and potential confounders. Categorical variables were analyzed using the chi-square or Fisher's exact test. Survival was analyzed using Kaplan–Meier estimates. Significance was set at <i>p</i> &lt; 0.05.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>No significant differences were found between the two implant types. Mean MBL from implantation to crown insertion was 1.10 ± 0.78 mm for titanium and 0.94 ± 0.67 mm for zirconia implants. No significant additional bone loss occurred over the subsequent year, with changes of 0.07 ± 0.55 mm and 0.08 ± 0.51 mm for titanium and zirconia, respectively. After 1 year, zirconia implants showed a 100% survival rate, while titanium implants showed 96.5% with two failures. At 1 year, differences in probing depths, plaque accumulation, and Papilla Bleeding Index were not statistically significant.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>After 1 year of loading, no statistically significant differences in MBL, implant survival, or peri-implant health were found between zirconia and titanium implants, indicating no clinical superiority. Zirconia implants may therefore be considered a viable alternative in single-tooth implant restorations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>The study is registered at the German Clinical Trial Register (No. DRKS 00013209) as well as at the Federal Office of Public Health's (FOPH) portal for human research in Switzerland (kofam.ch)</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 4","pages":"496-508"},"PeriodicalIF":5.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70094","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146021339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Clinical, Radiographic and Esthetic Outcomes of Zirconia Dental Implants: A 10-Year Prospective Multicenter Study","authors":"S. Roehling,&nbsp;K. H. Bormann,&nbsp;M. M. Bornstein,&nbsp;S. Laval,&nbsp;F. Thieringer,&nbsp;M. Gahlert","doi":"10.1111/clr.70089","DOIUrl":"10.1111/clr.70089","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to prospectively investigate the long-term clinical performance of a commercially available one-piece zirconia dental implant system over 10 years.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A multicenter, open-label study was conducted at three clinical centers in Germany. Forty-four patients with single-tooth gaps meeting specific inclusion criteria received 44 yttria-stabilized zirconia (Y-TZP) implants featuring a sandblasted and acid-etched (ZLA) surface. Clinical and radiographic follow-ups were performed at 1, 3, 5, and 10 years to assess implant survival, success, peri-implant bone levels, and esthetic outcomes using Pink Esthetic Score (PES) and White Esthetic Score (WES).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>At the 10-year follow-up, 35 patients with 35 implants were available for evaluation. The estimated 10-year survival rate was 97.7% (95% CI: 97.27–98.13). Three implants (8.6%) showed biological complications, including peri-implant mucositis in 2 implants (5.7%) and peri-implantitis in 1 implant (2.9%), leading to a success rate of 91.4% (95% CI: 76.9–97.8). Peri-implant bone loss was moderate, averaging 1.20 (±0.61) mm over 10 years, with stable bone levels observed after the initial remodeling phase. Esthetic outcomes revealed a slight increase in PES (7.4 to 7.8) and a minor decrease in WES (7.0 to 6.7) between years 5 and 10.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Zirconia implants demonstrated high long-term survival and success rates, moderate bone loss, and favorable esthetic outcomes. These findings support their use as a clinically reliable and esthetically acceptable long-term alternative to titanium implants. However, the limited sample size highlights the need for further confirmation in larger cohorts.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 4","pages":"439-452"},"PeriodicalIF":5.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146014935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Oral Hygiene Instructions in the Resolution of Peri-Implant Mucositis. A Randomized Controlled Trial","authors":"Beatriz de Tapia,&nbsp;Álvaro Babiano,&nbsp;Maria Vittoria Oreglia,&nbsp;Cristina Valles,&nbsp;Jose Nart","doi":"10.1111/clr.70098","DOIUrl":"10.1111/clr.70098","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To determine whether oral hygiene instructions (OHI) alone can be effective in the treatment of peri-implant mucositis (PM).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A randomized clinical trial with 56 PM patients was conducted. Participants were assigned to OHI (<i>n</i> = 28) or OHI + Mechanical Instrumentation (MI) (<i>n</i> = 28). Clinical [modified bleeding index (mBI), disease resolution] and microbiological parameters were assessed at baseline (T1), 1 month (T2), and 3 months (T3). Standardized periapical radiographs were taken at T1 and T3. Outcomes were analyzed at patient- and implant-level.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>48 patients with 118 implants were analyzed (52 in OHI; 66 in OHI + MI). At T3, success rates were 39.1% (OHI) and 56% (OHI + MI) at the patient level, and 36.4% (OHI) versus 67.3% (OHI + MI) at the implant level. Both groups showed a significant reduction in mBI (<i>p</i> &lt; 0.001). Intergroup differences were not statistically significant, though greater divergence was noted at T3. At the patient level, higher FMPI/FMBI at 3 months predicted lower success (<i>p</i> &lt; 0.05), whereas compliance improved outcomes (OR = 11.4, <i>p</i> = 0.004). At the implant level, failure was associated with OHI-only therapy, non-compliance, and higher mPI (all <i>p</i> = 0.001). History of periodontitis was a negative prognostic factor, linked to higher mBI at T3 (<i>p</i> = 0.010).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>OHI achieved resolution of PM in a considerable proportion of patients, particularly among compliant individuals. However, a history of periodontitis and posterior implant location negatively influenced outcomes. These findings highlight the importance of patient adherence and implant accessibility, while reaffirming the critical adjunctive role of MI in optimizing therapeutic success.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 4","pages":"509-522"},"PeriodicalIF":5.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.70098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146196388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}