Clinical Oral Implants Research最新文献

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Evaluation of the Accuracy, Surgical Time, and Learning Curve of Freehand, Static, and Dynamic Computer-Assisted Implant Surgery in an In Vitro Study. 在体外研究中评估徒手、静态和动态计算机辅助植入手术的准确性、手术时间和学习曲线。
IF 4.3 1区 医学
Clinical Oral Implants Research Pub Date : 2025-01-21 DOI: 10.1111/clr.14403
Joscha Gabriel Werny,Shengchi Fan,Leonardo Diaz,Bilal Al-Nawas,Keyvan Sagheb,Matthias Gielisch,Eik Schiegnitz
{"title":"Evaluation of the Accuracy, Surgical Time, and Learning Curve of Freehand, Static, and Dynamic Computer-Assisted Implant Surgery in an In Vitro Study.","authors":"Joscha Gabriel Werny,Shengchi Fan,Leonardo Diaz,Bilal Al-Nawas,Keyvan Sagheb,Matthias Gielisch,Eik Schiegnitz","doi":"10.1111/clr.14403","DOIUrl":"https://doi.org/10.1111/clr.14403","url":null,"abstract":"OBJECTIVESThis experimental study compared the accuracy of implant insertion using the free-hand (FH) technique, static computer-aided surgery (S-CAIS), or dynamic computer-assisted surgery (D-CAIS) and to evaluate the correlation of learning curves between surgeons' experience and surgical time.MATERIALS AND METHODSThirty-six models were randomly assigned to three groups (FH, n = 12; S-CAIS, n = 12; D-CAIS, n = 12). Each model was planned to receive four implants in the maxillary anterior and posterior regions. Twelve participants, six experienced surgeons, and six dental students were included in this study. The primary outcome was the deviation between the planned and final implant placement from each group. Secondary outcomes were each technique's learning curve regarding surgical time.RESULTSThe average deviation at implant platform, apex and gradual deviation with FH technique were 1.31 ± 0.88 mm, 1.75 ± 0.9 mm and 6.67° ± 3.70°, respectively. The average deviation of implant platform, apex and angular in S-CAIS were 0.67 ± 0.32 mm, 1.00 ± 0.39 and 2.66° ± 1.77°, respectively. The average deviation of implant platform, apex and angular in D-CAIS were 1.14 ± 0.70 mm, 1.23 ± 0.58 and 3.20° ± 2.16°, respectively. Significant discrepancies at the implant platform, implant apex, and angular deviation were found between all surgical methods (p < 0.016). Learning curves were evident after multiple implant insertions using both freehand and S-CAIS.CONCLUSIONThe findings indicate that computer-assisted implant insertion leads to a more precise implant alignment than implants inserted freehand in an experimental set-up.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"24 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142991691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction of Peri‐Implant Buccal Bone Dehiscence Following Sub‐Periosteal Peri‐Implant Augmented Layer Technique With Either Block or Particulate Xenograft: A Retrospective Study 块状或颗粒状异种移植修复骨膜下种植体周围增强层技术后颊部骨裂的回顾性研究
IF 4.3 1区 医学
Clinical Oral Implants Research Pub Date : 2025-01-20 DOI: 10.1111/clr.14400
Mattia Severi, Franzini Chiara, Anna Simonelli, Chiara Scapoli, Leonardo Trombelli
{"title":"Correction of Peri‐Implant Buccal Bone Dehiscence Following Sub‐Periosteal Peri‐Implant Augmented Layer Technique With Either Block or Particulate Xenograft: A Retrospective Study","authors":"Mattia Severi, Franzini Chiara, Anna Simonelli, Chiara Scapoli, Leonardo Trombelli","doi":"10.1111/clr.14400","DOIUrl":"https://doi.org/10.1111/clr.14400","url":null,"abstract":"ObjectiveTo evaluate the effectiveness of Sub‐periosteal Peri‐implant Augmented Layer (SPAL) technique performed with deproteinized bovine bone mineral (DBBM), delivered either as particulate (pDBBM) or block (bDBBM), in correcting a peri implant bone dehiscence (PIBD). Implants showing a thick (≥ 2 mm) peri‐implant buccal bone plate (PBBP) at placement were also examined.Material and MethodsPatients with a PIBD ≥ 1 mm, treated with SPAL with either pDBBM (SPAL<jats:sub>particulate</jats:sub>) or bDBBM (SPAL<jats:sub>block</jats:sub>), and patients with an implant showing a PBBP ≥ 2 mm at insertion (CONTROL) were included. Re‐entry was performed either at 6 months (SPAL groups) or 3 months (CONTROL). The rate of patients presenting no PIBD at re‐entry was the primary outcome. Bone dehiscence height (BDH) and width (BDW), thickness of buccal tissues (BTT) and marginal bone level (MBL) were secondary outcomes.ResultsThirty‐nine implants in 39 patients (14 in SPAL<jats:sub>particulate</jats:sub>,14 in SPAL<jats:sub>block</jats:sub> and 11 in CONTROL) were analyzed. No PIBD were found in SPAL<jats:sub>particulate</jats:sub> whereas in SPAL<jats:sub>block</jats:sub> one PIBD was present. Two patients in CONTROL presented a PIBD. A reduction in both BDH and BDW was observed in both SPAL<jats:sub>particulate</jats:sub> (2.7 ± 1.6 mm for BDH and 3.9 ± 0.2 mm for BDW) and SPAL<jats:sub>block</jats:sub> (2.5 ± 1.8 mm for BDH and 3.8 ± 1.1 mm for BDW). SPAL<jats:sub>block</jats:sub> showed a higher BTT than SPAL<jats:sub>particulate</jats:sub> at re‐entry (3.6 ± 1.3 mm for SPAL<jats:sub>block</jats:sub> and 2.6 ± 0.6 mm for SPAL<jats:sub>particulate</jats:sub>, <jats:italic>p</jats:italic> = 0.0160). All groups showed similar MBL.ConclusionSPAL performed with either a pDBBM or bDBBM is similarly effective in correcting a PIBD as well as in increasing BTT.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"6 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142989918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dental Implant Rehabilitation in Patients Carrying WNT10A Mutations With Different Molecular Statuses and Phenotypes: A Retrospective Cohort Study 携带不同分子状态和表型的WNT10A突变患者的牙种植康复:一项回顾性队列研究
IF 4.3 1区 医学
Clinical Oral Implants Research Pub Date : 2025-01-18 DOI: 10.1111/clr.14402
Jiaqi Dou, Qinggang Dai, Xinbo Yu, Yining He, Yuwei Dai, Feng Wang, Yiqun Wu
{"title":"Dental Implant Rehabilitation in Patients Carrying WNT10A Mutations With Different Molecular Statuses and Phenotypes: A Retrospective Cohort Study","authors":"Jiaqi Dou, Qinggang Dai, Xinbo Yu, Yining He, Yuwei Dai, Feng Wang, Yiqun Wu","doi":"10.1111/clr.14402","DOIUrl":"https://doi.org/10.1111/clr.14402","url":null,"abstract":"Objectives<jats:italic>WNT10A</jats:italic> mutations are associated with tooth agenesis. This study aimed to assess the clinical outcomes of dental implants in patients carrying <jats:italic>WNT10A</jats:italic> mutations with different molecular statuses and phenotypes over a long‐term follow‐up period.Materials and MethodsPatients with tooth agenesis were screened by whole‐exome sequencing (WES) from January 2010 to September 2023. Carriers of pathogenic <jats:italic>WNT10A</jats:italic> mutations who underwent subsequent dental implant therapy were evaluated.ResultsWES identified 66 patients with tooth agenesis carrying <jats:italic>WNT10A</jats:italic> mutations. Of these, 27 patients (11 males/16 females; mean age 19.6 years) met the inclusion criteria. Homozygotes had significantly more missing teeth (24.4 ± 3.8) than heterozygotes (10.9 ± 5.1, <jats:italic>p</jats:italic> &lt; 0.0001) and compound heterozygotes (13.8 ± 3.5, <jats:italic>p</jats:italic> = 0.001). A total of 160 conventional implants were placed. Seven implants were lost in four patients before final prosthesis placement, resulting in overall failure rates of 14.8% at the subject level and 4.4% at the implant level. The 5‐year cumulative survival rate (range: 0.23–12.74 years) was 85.2% and 95.6% at the subject and implant levels, respectively. The mean marginal bone loss (MBL) was 0.80 mm (95% CI: 0.59–1.02). Subgroup analysis revealed higher MBL in homozygotes (<jats:italic>p</jats:italic> = 0.002), sites requiring extensive bone augmentation (<jats:italic>p</jats:italic> = 0.016), anterior regions (<jats:italic>p</jats:italic> = 0.031), and full‐arch bridge cases (<jats:italic>p</jats:italic> &lt; 0.0001). Patient satisfaction and OHIP‐C49 scores were favorable.ConclusionsImplant rehabilitation is predictable for patients with <jats:italic>WNT10A</jats:italic> mutations. However, increased MBL observed in homozygotes with severe tooth agenesis and in cases requiring extensive alveolar bone augmentation highlights the importance of genetic diagnosis prior to implant therapy in patients with severe tooth agenesis.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"83 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142988541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NOTIFICATION: Human Fetal Osteoblast Behavior on Zirconia Dental Implants and Zirconia Disks With Microstructured Surfaces. An Experimental In Vitro Study 通知:人类胎儿成骨细胞在氧化锆牙科植入物和具有微结构表面的氧化锆盘上的行为。体外实验研究
IF 4.3 1区 医学
Clinical Oral Implants Research Pub Date : 2025-01-13 DOI: 10.1111/clr.14395
{"title":"NOTIFICATION: Human Fetal Osteoblast Behavior on Zirconia Dental Implants and Zirconia Disks With Microstructured Surfaces. An Experimental In Vitro Study","authors":"","doi":"10.1111/clr.14395","DOIUrl":"https://doi.org/10.1111/clr.14395","url":null,"abstract":"","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"27 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142974585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abaloparatide Enhances Bone Regeneration in Extraction Socket Dental Implant Defects: An Experimental In Vivo Study. 阿巴巴拉肽促进牙槽缺损骨再生:体内实验研究。
IF 4.8 1区 医学
Clinical Oral Implants Research Pub Date : 2025-01-09 DOI: 10.1111/clr.14397
Jessica Latimer, Birtan Yilmaz, Balazs Feher, Takahiko Shiba, Tobias Fretwurst, Bruce Mitlak, Beate Lanske, Paul Kostenuik, William V Giannobile
{"title":"Abaloparatide Enhances Bone Regeneration in Extraction Socket Dental Implant Defects: An Experimental In Vivo Study.","authors":"Jessica Latimer, Birtan Yilmaz, Balazs Feher, Takahiko Shiba, Tobias Fretwurst, Bruce Mitlak, Beate Lanske, Paul Kostenuik, William V Giannobile","doi":"10.1111/clr.14397","DOIUrl":"10.1111/clr.14397","url":null,"abstract":"<p><strong>Objective: </strong>Abaloparatide (ABL) is a synthetic parathyroid hormone-related protein analog developed as an anabolic drug to treat osteoporosis. ABL increases bone mineral density (BMD) of the long bones and spine; however, the influence of ABL on alveolar bone regeneration remains unknown. This study assessed the effects of systemic ABL administration on tooth extraction socket healing and dental implant osseointegration in a preclinical rodent model.</p><p><strong>Methods: </strong>Sprague-Dawley rats received daily subcutaneous injection of ABL (25 μg/kg) or vehicle (VEH) at the time of maxillary first molar (M1) extraction surgery; animals underwent either: (1) unilateral M1 extraction followed by sacrifice at 10 or 42d or (2) bilateral M1 extraction followed by staged implant placement in osteotomies with standardized defects and sacrifice at 21 or 28d.</p><p><strong>Results: </strong>Micro-computed tomography (micro-CT) analysis demonstrated that ABL increased bone volume fraction (p = 0.004) and bone mineral density (BMD) (p = 0.006) of regenerated extraction sockets at 42d. Micro-CT of the femur validated systemic effects of ABL, showing greater trabecular BMD after 6 (p < 0.01), 9 (p < 0.001), and 14 (p < 0.001) weeks of treatment. Histomorphometry confirmed a higher mineralized bone area with ABL treatment in extraction sockets at 42d (p = 0.03) and in the regenerated peri-implant bone at 21d post-implant placement (p = 0.01) compared to control.</p><p><strong>Conclusion: </strong>Systemic ABL administration enhances osteogenesis in extraction sockets prior to implant placement and accelerates peri-implant bone formation in the early phase of healing in the present rodent model.</p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Additional Cover 额外的封面
IF 4.8 1区 医学
Clinical Oral Implants Research Pub Date : 2025-01-06 DOI: 10.1111/clr.14399
{"title":"Additional Cover","authors":"","doi":"10.1111/clr.14399","DOIUrl":"10.1111/clr.14399","url":null,"abstract":"<p>The inside back cover image is based on the Original article <i>Comparison of Different Intraoral Scanners With Prefabricated Aid on Accuracy and Framework Passive Fit of Digital Complete-Arch Implant Impression: An In Vitro Study</i> by Xiao-Meng Zhang et al., https://doi.org/10.1111/clr.14353.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"36 1","pages":"ii"},"PeriodicalIF":4.8,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/clr.14399","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142935093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
One‐Piece Monolithic Zirconia Single Tooth Implant‐Supported Restorations in the Posterior Region: A 1‐Year Prospective Case Series Study 后牙区单片氧化锆单牙种植体支撑修复体:1年前瞻性病例系列研究
IF 4.3 1区 医学
Clinical Oral Implants Research Pub Date : 2024-12-23 DOI: 10.1111/clr.14396
Vincent J. J. Donker, Henny J. A. Meijer, Wim Slot, Arjan Vissink, Gerry M. Raghoebar
{"title":"One‐Piece Monolithic Zirconia Single Tooth Implant‐Supported Restorations in the Posterior Region: A 1‐Year Prospective Case Series Study","authors":"Vincent J. J. Donker, Henny J. A. Meijer, Wim Slot, Arjan Vissink, Gerry M. Raghoebar","doi":"10.1111/clr.14396","DOIUrl":"https://doi.org/10.1111/clr.14396","url":null,"abstract":"ObjectiveTo assess the clinical, radiographic and patient‐reported outcome measures, and the success of screw‐retained one‐piece monolithic zirconia implant‐supported restorations in the posterior region during a 1‐year follow‐up.MethodsIn a prospective case series, 50 single molar sites in the posterior region of 41 patients with a minimum age of 18 years and sufficient bone volume for placing an implant (≥ 8 mm) and space for an anatomical restoration were included. Following prosthetic‐driven digital three‐dimensional treatment planning, a tissue‐level implant with an internal connection was inserted during a one‐stage surgical procedure. Three months later, the implant was restored with a screw‐retained one‐piece monolithic zirconia restoration. Clinical, radiographic and patient‐reported outcome measures, and restoration survival and success according to the modified USPHS criteria were assessed at baseline prior to and immediately after implant placement, and 1‐month and 1‐year after definitive restoration placement.ResultsAt the 1‐year follow‐up, 1 implant had been lost (implant survival rate 98%) hence, 49 restorations were evaluated. The restoration survival and success rates were 100% and 98%, respectively. Plaque, calculus, bleeding and suppuration on probing and peri‐implant inflammation were absent in most cases. The mean (<jats:italic>SD</jats:italic>) marginal bone level change between implant placement and the 1‐year follow‐up was −0.14 mm (0.27) on the mesial and −0.25 mm (0.31) on the distal side. The mean (<jats:italic>SD</jats:italic>) patient satisfaction (0–10) was 9.2 (0.8) at the 1‐year evaluation.ConclusionOne‐piece monolithic zirconia implant‐supported restorations exhibited favourable outcomes over 1 year in situ.Trial Registration: Registered in the National Trial Register (NL9059)","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"20 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142874321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Exomass‐Related Artefacts Caused by Dental Implants of Different Materials in Cone‐Beam Computed Tomography Scans: An Ex Vivo Study 在锥形束计算机断层扫描中评估不同材料牙种植体引起的外质量相关伪影:一项离体研究
IF 4.3 1区 医学
Clinical Oral Implants Research Pub Date : 2024-12-21 DOI: 10.1111/clr.14394
Matheus L. Oliveira, Dorothea Dagassan‐Berndt, Matheus Sampaio‐Oliveira, Michelle Simonek, Sebastian Kühl, Michael M. Bornstein
{"title":"Evaluation of Exomass‐Related Artefacts Caused by Dental Implants of Different Materials in Cone‐Beam Computed Tomography Scans: An Ex Vivo Study","authors":"Matheus L. Oliveira, Dorothea Dagassan‐Berndt, Matheus Sampaio‐Oliveira, Michelle Simonek, Sebastian Kühl, Michael M. Bornstein","doi":"10.1111/clr.14394","DOIUrl":"https://doi.org/10.1111/clr.14394","url":null,"abstract":"ObjectivesTo evaluate the influence of different dental implant materials within the exomass on the image quality in cone‐beam computed tomography (CBCT).Material and MethodsFive pig jaws were scanned using four CBCT devices, first without any dental implants, followed by scans with three dental implants of the same material—pure titanium, titanium‐zirconium alloy, and zirconium dioxide. Two fields of view (FOVs) were used for each device to position the implants in the exomass of a small FOV and within a large FOV. Voxel values were obtained from tubes containing a radiopaque solution to calculate mean voxel value (MVV), voxel value inhomogeneity (VVI), and image noise (IN), which were compared across implant materials and FOVs using repeated measures analysis of variance (<jats:italic>α</jats:italic> = 0.05). Three observers independently scored image quality using a 5‐point scale.ResultsIn general, MVV remained unaffected, except for a significant increase in the X800 device when titanium or titanium‐zirconium alloy implants were in the exomass of a small FOV (<jats:italic>p</jats:italic> ≤ 0.05). A trend of increased VVI was observed when implants were in the exomass of a small FOV, with a greater effect for zirconium dioxide, followed by titanium‐zirconium alloy and titanium. IN was higher when implants were in the exomass, especially for zirconium dioxide implants (<jats:italic>p</jats:italic> ≤ 0.05). Image quality perception was consistent overall, though zirconium dioxide implants in both FOVs resulted in diminished quality.ConclusionsThe presence of implants in the exomass can negatively affect CBCT image quality, with zirconium dioxide having the greatest impact.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"268 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142867147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bone Substitute Material in the Surgical Therapy of Peri-Implantitis-3-Year Outcomes of a Randomized Controlled Trial. 骨替代材料在种植体周围炎手术治疗中的应用——一项3年随机对照试验的结果。
IF 4.8 1区 医学
Clinical Oral Implants Research Pub Date : 2024-12-20 DOI: 10.1111/clr.14393
Lamija Alibegovic, Anna Trullenque-Eriksson, Alberto Ortiz-Vigón, Adrián Guerrero, Mauro Donati, Eriberto Bressan, Karolina Karlsson, Carlotta Dionigi, Erik Regidor, Yuki Ichioka, Cristiano Tomasi, Paolo Ghensi, Dennis Schaller, Ingemar Abrahamsson, Tord Berglundh, Jan Derks
{"title":"Bone Substitute Material in the Surgical Therapy of Peri-Implantitis-3-Year Outcomes of a Randomized Controlled Trial.","authors":"Lamija Alibegovic, Anna Trullenque-Eriksson, Alberto Ortiz-Vigón, Adrián Guerrero, Mauro Donati, Eriberto Bressan, Karolina Karlsson, Carlotta Dionigi, Erik Regidor, Yuki Ichioka, Cristiano Tomasi, Paolo Ghensi, Dennis Schaller, Ingemar Abrahamsson, Tord Berglundh, Jan Derks","doi":"10.1111/clr.14393","DOIUrl":"https://doi.org/10.1111/clr.14393","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the potential mid-term benefit of the use of a bone substitute material in the reconstructive surgical treatment of peri-implantitis.</p><p><strong>Methods: </strong>A total of 120 subjects (127 implants) affected by peri-implantitis were followed over 3 years in a multicenter randomized clinical trial. Participants had been randomized to either control (access flap surgery) or test group (access flap surgery and bone substitute material). Clinical, radiographic, and patient-reported outcomes were assessed. The primary outcome was a composite measure including probing pocket depth ≤ 5 mm, absence of bleeding and suppuration on probing, soft tissue recession ≤ 1 mm, and implant neither reoperated nor lost. In an additional outcome (disease resolution), we allowed for one bleeding site and did not consider recession.</p><p><strong>Results: </strong>While 14 implants (11%) were lost and a second surgical intervention had been performed at 3 implants (2.4%), pronounced improvements of clinical parameters were noted at remaining implants in both treatment groups at the 3-year follow-up. This was illustrated by a 3.2-3.5 mm reduction in probing pocket depth and a marginal bone level gain of 1.1-1.3 mm. The primary composite outcome, however, was only achieved at 14% of implants. The second composite outcome defining disease resolution was accomplished at 39% of implants. Patient-reported outcomes were generally favorable.</p><p><strong>Conclusion: </strong>At 3 years, the use of a bone substitute material in the surgical therapy of peri-implantitis did not result in a clear benefit over access flap surgery alone.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: NCT0307706.</p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sinus Bone Graft Stability and Implant Survival Following Transalveolar Sinus Floor Elevation in Severely Atrophic Maxilla: A Retrospective Study With 5-8 Years of Follow-Up. 上颌严重萎缩患者经牙槽窦底抬高后窦骨移植物稳定性和种植体存活:一项5-8年随访的回顾性研究。
IF 4.8 1区 医学
Clinical Oral Implants Research Pub Date : 2024-12-18 DOI: 10.1111/clr.14392
Yingjie Mao, Yihan Shen, Jie Dai, Tian Lu, Yefeng Wu, Yali Shi, Fuming He
{"title":"Sinus Bone Graft Stability and Implant Survival Following Transalveolar Sinus Floor Elevation in Severely Atrophic Maxilla: A Retrospective Study With 5-8 Years of Follow-Up.","authors":"Yingjie Mao, Yihan Shen, Jie Dai, Tian Lu, Yefeng Wu, Yali Shi, Fuming He","doi":"10.1111/clr.14392","DOIUrl":"https://doi.org/10.1111/clr.14392","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the clinical and radiographic results of transalveolar sinus floor elevation (TSFE) with grafting in cases of severely atrophic maxilla.</p><p><strong>Materials and methods: </strong>A retrospective analysis of clinical and radiographic data was conducted. Between 2015 and 2018, a total of 105 implants were placed in 105 patients over a follow-up period of 5-8 years. Implant failures and endo-sinus bone gain (ESBG) were assessed. Statistical models were established to investigate the potential influencing factors of implant survival and ESBG.</p><p><strong>Results: </strong>Six patients with six implants were lost, resulting in cumulative survival rates of 94% for both patient- and implant-based analyses. The 8-year cumulative survival rate was significantly lower for residual bone height (RBH) < 4 mm (88%) compared to RBH 4-6 mm (98%). ESBG ≥ 4 mm and ESBG ≥ 6 mm were observed in 89.90% and 58.59% of implant sites, respectively. According to the log-rank Mantel-Cox analysis results, none of the factors examined were significantly related to implant failure, except for RBH (p = 0.038) at baseline. The linear mixed-model regression results showed that the final ESBG was positively correlated with implant insertion site (p = 0.003), implant length (p < 0.001), sinus floor elevation (SFE) methods (p = 0.010), and RBH (p < 0.001).</p><p><strong>Conclusions: </strong>Within the limitations of this study, it has been established that TSFE with grafting was a reliable method for implant placement in the posterior atrophic maxilla ridges with RBH ranging from 4 to 6 mm. Nevertheless, caution was advised when considering its application in cases where the initial bone height falls below 4 mm.</p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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