Clinical Oral Implants Research最新文献

{"title":"Peri-Implant Marginal Bone Changes Using High-Speed Drilling With Irrigation Versus Low-Speed Drilling Without Irrigation: A Randomized Clinical Trial With 12 Months of Follow-Up.","authors":"Juan Carlos Bernabeu-Mira, Miguel Peñarrocha-Diago, Luigi Canullo, Fabio Camacho-Alonso, Julio Rojo-Sanchis, David Peñarrocha-Oltra","doi":"10.1111/clr.14416","DOIUrl":"https://doi.org/10.1111/clr.14416","url":null,"abstract":"<p><strong>Objective: </strong>To analyse marginal bone level changes at implants placed using high-speed drilling (800 rpm) with irrigation versus low-speed drilling (150 rpm) without irrigation. Peri-implant soft-tissue parameters were assessed and the influence of bone density and vertical dimensions of supracrestal soft tissue on marginal bone level changes was evaluated.</p><p><strong>Material and methods: </strong>Patients with a single posterior edentulous area were included in a randomized parallel single-blinded clinical trial. The study groups were: high-speed drilling with irrigation (CG:control group) and low-speed drilling without irrigation (TG:test group). Marginal bone level changes were measured using parallelized periapical radiographs during 12-months. Probing depth, bleeding on probing, plaque index, buccal keratinized mucosa, suppuration and recession were measured. The mean total bone density was evaluated in Hounsfield Units. Mann-Whitney U-test for non-parametric variables and t-test for parametric variables were employed.</p><p><strong>Results: </strong>A total of 66 patients were included (33 per group). The implant success rate was 100% for both groups according to Misch classification. No statistically significant differences were found regarding marginal bone loss (CG: -0.03 (0.17); TG: -0.01 (0.05)), bone remodeling (CG: 0.81 (0.64); TG: 0.86 (0.54)), or peri-implant soft tissue parameters (p > 0.05). Bone density showed no significant correlation with the peri-implant bone and soft-tissue changes. The vertical supracrestal soft tissue was inversely correlated to peri-implant bone remodeling.</p><p><strong>Conclusions: </strong>Within the limits, high-speed drilling with irrigation and low-speed drilling without irrigation had no statistically significant influence on the peri-implant marginal bone and soft tissue changes during 12 months of follow-up. These variables were not significantly influenced by bone density.</p><p><strong>Trial registration: </strong>Unique identification number: NCT05286866.</p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Effect of Abutment Height and Restoration Emergence Angle on Peri-Implant Bone Loss Progression: A Retrospective Analysis.","authors":"Jonathan Misch, Sawsan Abu-Reyal, Danyal Lohana, Obada Mandil, Muhammad H A Saleh, Junying Li, Hom-Lay Wang, Andrea Ravidà","doi":"10.1111/clr.14408","DOIUrl":"https://doi.org/10.1111/clr.14408","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to investigate the combined effect of trans-mucosal abutment height (TmAH) and restorative emergence angle (REA) on marginal bone loss (MBL) around bone-level implants.</p><p><strong>Methods: </strong>Implant radiographs 12-18 months after crown placement (T0) and at least one year later (T1) were retrospectively analyzed. Sites were separated into four groups: Long/Narrow-Angle (LN) with TmAH > 2 mm and REA < 30°, Long/Wide-Angle (LW) with TmAH > 2 mm and REA ≥ 30°, Short/Narrow-Angle (SN) with TmAH < 2 mm and REA < 30°, and Short/Wide-Angle (SW) with TmAH < 2 mm and REA ≥ 30°. MBL was calculated, and multiple linear regression analysis was performed to control for patient-level and implant/prosthesis-level factors.</p><p><strong>Results: </strong>192 implants pertaining to 119 patients were included. Group significantly influenced MBL experience (p < 0.001). Group SW experienced on average 0.48 mm (95% CI: 0.25-0.71, p < 0.001), 0.43 mm (95% CI: 0.18-0.68, p = 0.001), and 0.25 mm (95% CI: 0.00-0.45, p = 0.013) greater MBL compared to Groups LN, LW, and SN, respectively. Group was also a significant factor impacting the development of peri-implantitis (p = 0.041), with Group SW displaying a roughly 4× greater likelihood of having peri-implantitis (PI) diagnosed compared to Groups LN (OR: 4.04; p = 0.091) and LW (OR: 4.19; p = 0.013). Every 1 mm increase in TmAH significantly decreased the likelihood of MBL > 0 mm (OR = 0.63; p = 0.003).</p><p><strong>Conclusions: </strong>Abutment height > 2 mm may play a role in reducing PI and MBL related to ≥ 30° REA around bone-level implants. REA was found to only be a significant factor when TmAH is less than 2 mm.</p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Vitro Assessment of the Potential Effect of Vertical Peri-Implant Soft Tissue Thickness on Nonsurgical and Surgical Implant Surface Decontamination Methods.","authors":"Annika Rahner, Peter Eickholz, Jan-Frederik Gueth, Tuǧba Zahn, Iulia Dahmer, Hari Petsos","doi":"10.1111/clr.14415","DOIUrl":"https://doi.org/10.1111/clr.14415","url":null,"abstract":"<p><strong>Objectives: </strong>In vitro analysis of the influence of vertical peri-implant soft tissue thickness (STT) on nonsurgical and surgical implant surface decontamination efficacy.</p><p><strong>Material and methods: </strong>A total of 360 implants were dipped in indelible color to imitate biofilm contamination, distributed to 30°, 60° or 90° angulated bone defect models and in subgroups of 40 assigned to a decontamination method (CUR: curette; SOSC: soundscaler; APA: air powder abrasion). Of these, 20 were subjected to a simulated STT of 1.5 or 3.0 mm, of which 10 were cleaned within a nonsurgical (NST) or surgical (ST) treatment. Uncleaned implant surface was determined by photographs. Surface changes were assessed using scanning electron micrographs (SEM).</p><p><strong>Results: </strong>The overall cleaning efficacy decreased significantly (APA > SOSC > CUR, p < 0.001). Cleaning efficacy failed to show a significant difference between both STTs (STT1.5: 63.68%, STT3.0: 63.26%; p = 0.877). Within respective STT, cleaning efficacy differed depending on the method and the approach (STT1.5: CUR: p = 0.169, SOSC: p = 0.004, APA: p < 0.001; STT3.0: CUR p < 0.001, SOSC: p < 0.001, APA: p < 0.001; STT1.5/NST, CUR: 82.34%, SOSC: 74.98%, APA: 93.60%; STT1.5/ST, CUR: 79.85%, SOSC: 65.37%, APA: 50.12%; STT3.0/NST, CUR: 83.19%, SOSC: 70.85%, APA: 92.31%; STT3.0/ST, CUR: 80.00%, SOSC: 64.61%, APA: 46.49%). Analysis of variance revealed significant associations of color remnants with the approach, the method used, and the defect angulation (p < 0.001). SEMs showed less surface damages after use of APA.</p><p><strong>Conclusions: </strong>In this In Vitro study no statistically significant influence of STT on the efficacy of surface decontamination could be detected. Treatment method, defect angle and approach were confirmed as predictors for the cleaning efficacy.</p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Bone Microstructure Derived From CBCT on the Accuracy of Robot-Assisted Implant Surgery: A Retrospective Study.","authors":"Wenxi Dong, Linhong Wang, Yuanna Zheng, Xulan Yang, Liheng Shen, Fan Yang, Yuchen Zheng","doi":"10.1111/clr.14414","DOIUrl":"https://doi.org/10.1111/clr.14414","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the influence of bone microstructure on the accuracy of robot-assisted dental implant surgery.</p><p><strong>Materials and methods: </strong>This retrospective study analyzed 52 patients who received robot-assisted implant surgery between January 2023 and October 2023. Cone beam computed tomography (CBCT) scans were used to evaluate bone microstructural parameters, including the bone volume (BV), tissue volume (TV), bone volume fraction (BV/TV), bone surface (BS), bone surface fraction (BS/BV), trabecular thickness (Tb.Th), and trabecular separation (Tb.Sp). Preoperative and postoperative CBCT data were used to evaluate implant accuracy, and the relationship between bone microstructure parameters and implant deviation including platform deviation, apex deviation, and angular deviation was statistically analyzed.</p><p><strong>Results: </strong>In robot-assisted implant surgery, BS/BV was a potential facilitator of several implant deviations, while BV/TV and Tb.Th were potential inhibitors of apex global deviation and angular deviation, respectively. Implant deviations were divided into two groups of large and small deviations by median, and the receiver operating characteristic (ROC) curve analysis showed that Tb.Th had the largest area under the ROC for predicting large apex global deviation, 0.711 (p < 0.001), with an optimal cutoff value > 0.179, a sensitivity and specificity of 70.37% and 76.92%.</p><p><strong>Conclusion: </strong>The study concluded that bone microstructure might affect the accuracy of dental implant placement in robotic surgeries. Incorporating bone quality assessments into preoperative planning may enhance the precision and outcomes of implant procedures, highlighting the potential for further refinement in robotic-assisted dental surgery techniques.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: ChiCTR2400085813.</p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Effects of Dynamic Navigation on the Accuracy and Outcomes of the Autogenous Bone Ring Technique for Vertical Ridge Augmentation: A Pilot Randomized Controlled Trial.","authors":"Yu-Chen Chang, Ning Zhu, Jiayu Liu, Xianming Gao, Gang Chen, Yu Zhang","doi":"10.1111/clr.14412","DOIUrl":"https://doi.org/10.1111/clr.14412","url":null,"abstract":"<p><strong>Objectives: </strong>Autogenous bone ring technique (BRT) is a one-stage vertical augmentation approach with simultaneous implant placement. The aim of this study was to compare the accuracy and efficacy of autogenous BRT assisted by dynamic navigation (DN) with freehand approach (FA) for vertical ridge augmentation.</p><p><strong>Materials and methods: </strong>Twenty-four patients eligible for autogenous BRT were randomly assigned to DN or FA groups. Digital preoperative design was conducted for both groups. BRT surgeries were executed with or without the aid of DN in the two groups. Accuracy outcomes evaluated angular and linear deviations at the bone ring in the donor site (BR-D), recipient site (BR-R), and implant entry/apex between planned and actual positions revealed by cone-beam computed tomography. Vertical augmentation-related outcomes, surgical complications, and patient-reported outcomes were assessed over 6 months.</p><p><strong>Results: </strong>Twenty-four patients underwent surgery while one was lost to follow-up. The DN group showed significantly lower mean (SD) BR-R angular (3.58 [2.07] vs. 8.77 [4.20]°) and entry deviation (1.43 [0.51] vs. 2.01 [0.70] mm). For BR-D, the DN group had significantly lower angular (4.80 [2.62] vs. 12.97 [6.26]°), entry (1.45 [0.96] vs. 3.52 [1.54] mm), and apex deviation (1.28 [0.64] vs. 3.50 [1.47] mm) compared to the FA group. Implant angular deviation (3.74 [2.14] vs. 9.17 [4.39]°) and apex deviation (1.75 [0.44] vs. 2.35 [0.82] mm) was significantly lower in the DN group. In the FA group, one patient exhibited temporary lower lip hypoesthesia. No significant differences were observed in vertical bone gain, resorption, or patient-reported outcomes.</p><p><strong>Conclusions: </strong>Compared to FA, DN may improve the accuracy of autogenous BRT procedures for vertical ridge augmentation while minimizing invasiveness.</p><p><strong>Trail registration: </strong>This study was registered at the Chinese Clinical Trial Registry (https://www.chictr.org.cn; Registration No. ChiCTR2200065585; registration date: 2022/11/09).</p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy, Safety, and Efficiency in Robotic-Assisted vs. Freehand Dental Implant Surgery: A 6-Month Follow-Up Randomized Controlled Trial.","authors":"Jiaxian Chen, Yulan Wang, Yi Bai, Yan Chen, Zhenqi Chen, Qi Yan, Yufeng Zhang","doi":"10.1111/clr.14413","DOIUrl":"https://doi.org/10.1111/clr.14413","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the implant accuracy, safety, and efficiency between robotic-assisted and freehand dental implant placement with a half-year follow-up.</p><p><strong>Methods: </strong>Patients requiring single-tooth implant restorations were recruited and randomized into two groups: robotic-assisted surgery and freehand implant surgery. The accuracy of implant positioning was compared by assessing immediate postoperative CBCT scans against preoperative planning software. Intraoperative and postoperative complications were recorded, and data were analyzed using an intention-to-treat approach. The time required for implant placement in each group was documented. A 6-month follow-up measured the implant survival rates.</p><p><strong>Results: </strong>The study included 24 patients (median age 36, 18 female). In the robotic-assisted surgery group, the average platform global deviation, apex global deviation, and angular deviation were 0.70 ± 0.11 mm, 0.70 ± 0.12 mm, and 1.09° ± 0.67°, respectively. In the freehand implant surgery group, these measures were 1.24 ± 0.59 mm, 2.13 ± 1.26 mm, and 7.43° ± 6.12°, respectively, with statistically significant differences. Regarding the duration of surgery, the robotic-assisted surgery group required 18.8 ± 4.89 min. Intraoperative and postoperative complications were similar across both groups, and the implant survival rate was 100% in both groups at the 6-month follow-up.</p><p><strong>Conclusions: </strong>This study found that robot-assisted implant placement offers higher accuracy in implant positioning compared to freehand placement, while requiring longer operation times. Future developments should focus on simplifying the registration and design of robot systems to enhance efficiency and facilitate their broader clinical adoption.</p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full‐Arch Digital Implant Impression Trueness: An in Vivo Study","authors":"Vygandas Rutkūnas, Daniel Kuleš, Marta Revilla‐León, Mykolas Akulauskas, Liudas Auškalnis, Ieva Gendvilienė","doi":"10.1111/clr.14411","DOIUrl":"https://doi.org/10.1111/clr.14411","url":null,"abstract":"ObjectivesTo evaluate the trueness of maxillary and mandibular full‐arch implant digital impressions with and without additional reference objects.Material and MethodsSeventeen maxillary and 6 mandibular arches with four implants were randomly divided into a group with additional reference objects (wRO group, <jats:italic>n</jats:italic> = 12) and without them (woRO group, <jats:italic>n</jats:italic> = 11) and scanned with an intraoral scanner (IOS). For each jaw, the control model (CM) data was obtained to evaluate the deviations in the scan body positions in the wRO and woRO groups. CM and IOS data sets were imported into metrology software for distance and angle measurements between scan body pairs 1–2, 1–3, and 1–4. Unsigned values of distance and angle data differences between CM and IOS groups were used for further analysis.ResultsThe highest statistically significant (<jats:italic>p &lt; 0.05</jats:italic>) differences between distance and angulation measurements of the maxilla and mandible were observed in the 1–4 scan body pair group (136 ± 95 μm, 0.95° ± 0.79°; 362 ± 233 μm, 2.22° ± 2.11°, respectively). Distance deviations of the mandible were higher in all scan body pair groups. The woRO group had higher distance and angulation unsigned trueness values than in the wRO group, especially in the 1–4 scan body pair (224 ± 183 μm, 1.77° ± 1.76°;169 ± 162 μm, and 0.83° ± 0.57°, respectively).ConclusionsIOS for the full‐arch cases had statistically and clinically significant distance and angle deviations. Higher deviations were observed in the single mandibular scan body pair. The tendency of diminished distance and angular deviations with the utilization of the additional reference objects was observed, though these differences were not statistically significant.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"53 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143072378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial Effect and Cytocompatibility After Using Different Decontamination Methods on Titanium Implant Surfaces: An In Vitro Study","authors":"Andrea Alonso‐Español, Enrique Bravo, Ana Carrillo de Albornoz, María Martínez, Katharina Doll‐Nikutta, Andreas Winkel, Meike Stiesch, David Herrera, Bettina Alonso, Mariano Sanz","doi":"10.1111/clr.14410","DOIUrl":"https://doi.org/10.1111/clr.14410","url":null,"abstract":"AimTo evaluate in vitro the antibacterial efficacy and cytocompatibility of different implant‐decontamination methods, using both 2D and 3D peri‐implant mucosa models.MethodsFour decontamination methods [chlorhexidine (CHX), electrolytic treatment (GS), curcumin (CUR), xanthohumol (XN)] were compared in four independent experiments, three with a 2D peri‐implant mucosa model on titanium surfaces and another on a 3D peri‐implant mucosa model. These decontamination procedures were tested for their antibacterial effect using a multispecies biofilm model with <jats:styled-content style=\"fixed-case\"><jats:italic>Streptococcus oralis</jats:italic></jats:styled-content>, <jats:styled-content style=\"fixed-case\"><jats:italic>Actinomyces naeslundii</jats:italic></jats:styled-content>, <jats:styled-content style=\"fixed-case\"><jats:italic>Veillonella dispar</jats:italic></jats:styled-content>, and <jats:styled-content style=\"fixed-case\"><jats:italic>Porphyromonas gingivalis</jats:italic></jats:styled-content> for 24 h. Direct cytocompatibility evaluating the impact of the treatments on tissue cells as well as indirect cytocompatibility (colonization of treated implant surfaces by tissue cells) were also tested. Both outcomes were assessed by confocal laser scanning microscopy supported by neural networks.ResultsCHX demonstrated a strong alteration of cytocompatibility and antibacterial effect, but did not remove biofilm biomass. XN and CUR demonstrated antibacterial effect and biofilm removal action, as well as cytocompatibility. GS showed antibacterial capacity with a combination of areas completely clean of biofilm with others in which a non‐vital biofilm remained. In the 3D peri‐implant mucosa model, XN and CUR showed maintenance of the mucosa integrity after treatment, whereas CHX and GS displayed disruption in the mucosal layers.ConclusionsPhytotherapeutics (CUR and XN) were the most cytocompatible substances and showed the largest antimicrobial effect. GS displayed antibiofilm activity with a localized “bubble‐shaped effect” and impaired tissue cell morphology and integrity, compromising cytocompatibility, and CHX showed antimicrobial capacity, without reducing biofilm biomass and with altered cytocompatibility.","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"36 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143056499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Five-Year Results of One-Piece Zirconia Oral Implants Supporting Three-Unit Fixed Dental Prostheses.","authors":"Ralf-Joachim Kohal, Kirstin Vach, Frank Butz, Sebastian Berthold Maximilian Patzelt, Felix Burkhardt","doi":"10.1111/clr.14407","DOIUrl":"https://doi.org/10.1111/clr.14407","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of the present prospective case series was to investigate the clinical and radiological outcome of one-piece zirconia implants fabricated from 3Y-TZP with a moderately roughened endosseous surface (Sa = 1.24 μm) to support three-unit fixed dental prostheses (FDP) after five years in function.</p><p><strong>Materials and methods: </strong>Twenty-seven patients received a total of 54 implants in a one-stage surgery with immediate provisionalization. Peri-implant bone loss was assessed using standardized radiographs. Additionally, soft-tissue parameters were analyzed. Statistical analyses were conducted using linear mixed regression models and Wilcoxon Signed Rank tests (p < 0.05). All patients participated in an annual maintenance program.</p><p><strong>Results: </strong>Eighteen implants were lost up to the 5-year follow-up, resulting in a cumulative survival rate of 66.67%. The mean marginal bone loss of the remaining implants amounted to 1.89 mm. Probing depth, clinical attachment loss, and bleeding on probing increased from prosthesis insertion to the 5-year follow-up, while the plaque index showed no significant changes during the same period.</p><p><strong>Conclusions: </strong>The investigated one-piece zirconia implant showed low survival rates as compared to previously reported survival rates of one-piece zirconia or two-piece titanium implants. Implant failure was attributed to peri-implantitis, leading to the necessity of implant removal. The implant is not commercially available.</p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Nonsurgical Mechanical Debridement With or Without Chlorhexidine Formulations in the Treatment of Peri‐Implant Mucositis. A Randomized Placebo‐Controlled Clinical Trial","authors":"Gaetano Isola, Alessandro Polizzi, Maria Santagati, Angela Alibrandi, Vincenzo Iorio‐Siciliano, Luca Ramaglia","doi":"10.1111/clr.14405","DOIUrl":"https://doi.org/10.1111/clr.14405","url":null,"abstract":"ObjectivesTo evaluate the treatment of peri‐implant mucositis (PM) using a nonsurgical submarginal peri‐implant instrumentation (NSPI) with or without chlorhexidine (CHX) solutions.MethodsFifty‐six patients (28 per group) were randomly assigned to the test (NSPI + 0.12% mouthwash and subgingival CHX irrigation plus tongue brushing with 1% CHX gel) or the control group (NSPI + placebo mouthwash and subgingival placebo irrigation plus tongue brushing with placebo gel). At baseline, 1, 3, 6 months, bleeding on probing (BOP), probing pocket depth (PPD), modified gingival index (mGI), modified plaque index (mPlI), full‐mouth plaque score (FMPS), full‐mouth bleeding score (FMBS), and the proportions of &lt;jats:styled-content style=\"fixed-case\"&gt;&lt;jats:italic&gt;Aggregatibacter actinomycetemcomitans&lt;/jats:italic&gt;&lt;/jats:styled-content&gt;, &lt;jats:styled-content style=\"fixed-case\"&gt;&lt;jats:italic&gt;Porphyromonas gingivalis&lt;/jats:italic&gt;&lt;/jats:styled-content&gt;, &lt;jats:styled-content style=\"fixed-case\"&gt;&lt;jats:italic&gt;Tannerella forsythia&lt;/jats:italic&gt;,&lt;/jats:styled-content&gt; and &lt;jats:styled-content style=\"fixed-case\"&gt;&lt;jats:italic&gt;Treponema denticola&lt;/jats:italic&gt;&lt;/jats:styled-content&gt; were recorded. The BOP reduction was set as a primary outcome. Data were analyzed to assess BOP reduction at a 6‐month follow‐up and to identify significant predictors of implant‐site BOP through mixed generalized linear regression.ResultsAfter 6 months in both groups, a significant reduction of BOP, PD, mPlI, mGI, FMBS, and FMPS was noted (&lt;jats:italic&gt;p&lt;/jats:italic&gt; &lt; 0.05). However, at 6 months, the test group was more effective than the controls in reducing median BOP (∆values control/test: 39.3% [95% CI 37.4–42.3] vs. 48.7 [95% CI 46.5–51.2], &lt;jats:italic&gt;p&lt;/jats:italic&gt; = 0.044), as well as mPlI (&lt;jats:italic&gt;p&lt;/jats:italic&gt; = 0.041) and the proportion of &lt;jats:styled-content style=\"fixed-case\"&gt;&lt;jats:italic&gt;Treponema denticola&lt;/jats:italic&gt;&lt;/jats:styled-content&gt; (&lt;jats:italic&gt;p&lt;/jats:italic&gt; = 0.039). Moreover, the implant‐sites BOP reduction was significantly influenced by test treatment (&lt;jats:italic&gt;p&lt;/jats:italic&gt; &lt; 0.001), history of periodontitis (&lt;jats:italic&gt;p&lt;/jats:italic&gt; = 0.003), and a high number of cigarettes/day (&lt;jats:italic&gt;p&lt;/jats:italic&gt; = 0.002), the proportion of &lt;jats:styled-content style=\"fixed-case\"&gt;&lt;jats:italic&gt;Porphyromonas gingivalis&lt;/jats:italic&gt;&lt;/jats:styled-content&gt; (&lt;jats:italic&gt;p&lt;/jats:italic&gt; = 0.021) and &lt;jats:styled-content style=\"fixed-case\"&gt;&lt;jats:italic&gt;Tannerella forsythia&lt;/jats:italic&gt;&lt;/jats:styled-content&gt; (&lt;jats:italic&gt;p&lt;/jats:italic&gt; = 0.032).ConclusionsNSPI + CHX showed better results compared to placebo in implant‐sites BOP reduction. The high number of cigarettes/day and the proportion of &lt;jats:styled-content style=\"fixed-case\"&gt;&lt;jats:italic&gt;Porphyromonas gingivalis&lt;/jats:italic&gt;&lt;/jats:styled-content&gt; and &lt;jats:styled-content style=\"fixed-case\"&gt;&lt;jats:italic&gt;T. forsythia&lt;/jats:italic&gt;&lt;/jats:styled-content&gt; negatively influenced the BOP reduc","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"35 1","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}