Clinical PediatricsPub Date : 2025-10-01Epub Date: 2025-05-09DOI: 10.1177/00099228251339067
Ruogu Yu, Li Zhang, Xuemei Li, Qi Wang, Xiaobin Wu
{"title":"Effects of Nutritional Status on Treatment Outcomes and Prognosis of Infants With Bronchiolitis.","authors":"Ruogu Yu, Li Zhang, Xuemei Li, Qi Wang, Xiaobin Wu","doi":"10.1177/00099228251339067","DOIUrl":"10.1177/00099228251339067","url":null,"abstract":"<p><p>To explore how nutritional status impacts treatment efficacy and future asthma risk in infants with bronchiolitis. A retrospective analysis of 473 RSV-induced bronchiolitis cases from 2015 to 2018. No significant demographic differences. Obese infants showed increased respiratory distress, wheezing, and rapid breathing, with lower oxygen saturation. Elevated IgE and tumor necrosis factor-α (TNF-α) levels persisted in the obese group. A higher asthma incidence was observed after 5 years in this group. Nutritional status is crucial for bronchiolitis management; obesity prevention should be highlighted in asthma programs.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1447-1453"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-10-01Epub Date: 2025-05-04DOI: 10.1177/00099228251335861
Hasan Ari, Nur Berna Celik, Senay Savas-Erdeve, Semra Cetinkaya, Nursel Muratoglu Sahin
{"title":"The Crucial Role of Body Mass Index on Growth Hormone Stimulation Tests in Children: An Exploration of Potential Gender-Related Differences.","authors":"Hasan Ari, Nur Berna Celik, Senay Savas-Erdeve, Semra Cetinkaya, Nursel Muratoglu Sahin","doi":"10.1177/00099228251335861","DOIUrl":"10.1177/00099228251335861","url":null,"abstract":"<p><p>The aim of the study was to investigate whether there are any gender-related differences in growth hormone stimulation test (GHST) in prepubertal short children, with a particular emphasis on body mass index (BMI). Prepubertal patients who had two unprimed GHST using clonidine and L-dopa were included in this retrospective study. The anthropometrics and laboratory parameters were evaluated. Patients were categorized based on their peak growth hormone (GH) levels (GH <7 versus ≥7 ng/mL), stimulant agent, and gender. A total of 125 children (Male:Female = 75:50) were included. The mean age of the patients was 7.1 ± 3.0 years. lg-peak clonidine stimulated GH was associated with BMI standard deviation score (SDS) (β [95% CI] = 1.903 [1.665-2.140], <i>P</i> = .003) in females, and with IGF-SDS in males (β [95% CI] = 1.124 [0.910-1.339], <i>P</i> = .026). lg-peak L-dopa stimulated GH was associated with BMI SDS and IGF1-SDS (β [95% CI] = 1.327 [0.968-1.686], <i>P</i> = .009) in females. The blunted effect of BMI showed gender-related differences in the prepubertal pediatric patients.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1380-1387"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-10-01Epub Date: 2025-03-27DOI: 10.1177/00099228251330113
Katherine F Sweeny, Christine K Lee, Paul D Mitchell, Shavonne Osiakwan, Cosette Scott, Maureen M Jonas
{"title":"A Cross-Sectional Retrospective Review of Neuropsychiatric Comorbidities in Children With Non-Alcoholic Fatty Liver Disease.","authors":"Katherine F Sweeny, Christine K Lee, Paul D Mitchell, Shavonne Osiakwan, Cosette Scott, Maureen M Jonas","doi":"10.1177/00099228251330113","DOIUrl":"10.1177/00099228251330113","url":null,"abstract":"<p><p>This single-center cross-sectional retrospective chart review sought to define the prevalence of neuropsychiatric (NP) disorders among children with non-alcoholic fatty liver disease (NAFLD) compared to the general population. The prevalence rate of NP disorders was determined at diagnosis among children evaluated from 2006 to 2016. The NP disorder prevalence rates were compared to those reported in the 2016 National Survey of Children's Health (NSCH). 24.3% of 254 children with NAFLD reported to have at least 1 NP disorder compared to 16.9% of those in NSCH (relative risk [RR] = 1.44; <i>P</i> < .0001). More children had intellectual disability (ID) (4.5% vs 0.8%; RR = 5.43, <i>P</i> < .0001), depression (3.9% vs 2.2%; RR = 1.82, <i>P</i> = .0009), or autism spectrum disorder (ASD) (3.3% vs 2.0%; RR = 1.67, <i>P</i> = .047) in the Boston Children's Hospital (BCH) NAFLD cohort. The prevalence of 1 NP disorder was 29.4% in our cohort compared to 22.3% in NSCH (RR = 1.32; <i>P</i> = .007). Children with NAFLD have a higher rate of NP disorders compared to the general population.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1274-1280"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-10-01Epub Date: 2025-04-24DOI: 10.1177/00099228251333207
Ryan Dean, Jonathan Wan, Martine Sainvilus, Meagan Acevedo, Lauren Borchardt, Mariam Zeini, Nicole Armstrong, J Gene Chen
{"title":"Implementing a Successful Quality Improvement Curriculum With a Required Resident-Led Project in a Pediatric Residency Program.","authors":"Ryan Dean, Jonathan Wan, Martine Sainvilus, Meagan Acevedo, Lauren Borchardt, Mariam Zeini, Nicole Armstrong, J Gene Chen","doi":"10.1177/00099228251333207","DOIUrl":"10.1177/00099228251333207","url":null,"abstract":"<p><p>The Accreditation Council for Graduate Medical Education (ACGME) requires that residents receive training in quality improvement (QI). There is a lack of data regarding QI curricula during pediatrics training. Our aim was to examine the implementation of a QI curriculum in a university-affiliated, community-based pediatric residency. The curriculum includes didactics, faculty mentorship, and instructional worksheets, and culminates in a resident-led QI project with Plan-Do-Study-Act (PDSA) cycles. From 2018 to 2024, 97 residents completed 72 QI projects. The percentage of residents completing a project rose from 7% pre-implementation to 100% post-implementation. Of the projects, 65 (90%) were presented at regional research symposia, and 14 (19%) were presented at national or regional conferences. Frequent targets of projects included vaccinations (13% of all projects), breastfeeding (8%), asthma management (7%), mental health (7%), and nutrition and obesity (7%). A QI curriculum in a pediatric residency fosters resident-led QI, promotes the completion of projects, and engenders opportunities for conference presentations.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1249-1258"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-10-01Epub Date: 2025-02-26DOI: 10.1177/00099228251321925
Camila Aparicio-Llorente, Carlos R Oliveira, Christine Miller
{"title":"An Infectious Disease Mimicking Rheumatologic Disease in an Adolescent.","authors":"Camila Aparicio-Llorente, Carlos R Oliveira, Christine Miller","doi":"10.1177/00099228251321925","DOIUrl":"10.1177/00099228251321925","url":null,"abstract":"","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1312-1316"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12353391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-10-01Epub Date: 2025-05-17DOI: 10.1177/00099228251342316
Serhat Batibay, Gonca Karayagiz Muslu
{"title":"Evaluation of the Attitudes of Mothers With Children With Epilepsy Toward Rational Drug Use.","authors":"Serhat Batibay, Gonca Karayagiz Muslu","doi":"10.1177/00099228251342316","DOIUrl":"10.1177/00099228251342316","url":null,"abstract":"<p><p>Rational drug use is important in pediatric patients with epilepsy. In this descriptive study, it was aimed to evaluate the attitudes of mothers with children with epilepsy toward rational drug use. The sample of the study of 200 mothers with a child diagnosed with epilepsy. It was found that mothers administered over-the-counter medications 97.5% of the time, the mean scores of the mothers' rational drug use attitude scale differed depending on the variables such as the mother's age, education level, place of residence, number of children, age of the child with epilepsy, the child's continuous drug use and over-the-counter drug use for their child (<i>P</i> < .05). It was determined that over-the-counter drug use is common among mothers of children with epilepsy. Increasing the awareness of mothers who are in the risk group about rational drug use, and the continuity of education are important for drug compliance in pediatric epilepsy patients.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1462-1470"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-10-01Epub Date: 2025-05-09DOI: 10.1177/00099228251339361
Cemre Yaren Güngörenler, Tülay Tarsuslu
{"title":"Effect of Core Stabilization Exercises on Balance and Postural Control in Children with Obesity and Overweight.","authors":"Cemre Yaren Güngörenler, Tülay Tarsuslu","doi":"10.1177/00099228251339361","DOIUrl":"10.1177/00099228251339361","url":null,"abstract":"<p><p>The purpose of this study was to investigate the effect of core stabilization exercises (CSE) on balance and postural control in children with obesity and children with overweight. The study, which was planned as a quasi-experimental controlled study, was conducted with 46 children aged 7 to 10 years, 12 affected by obesity, 18 overweight, and 16 normal weight. Eight weeks of CSE were applied to all children. Children's balance, postural control, and core region endurance were evaluated before and after the exercises with McGill core endurance tests, flamingo balance test (FBT), functional reach test (FRT), Y balance test (YBT). SPSS 25.0 package program was used for statistical analyses. The results showed that 8 weeks of CSE provided significant improvements in McGill core endurance tests, FBT, FRT, and YBT in children (<i>P</i> < .05). Since excessively increased weight can cause a decrease in performance, it can also reduce the ability to achieve the greatest effect from the applied exercise approaches.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1425-1436"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-10-01Epub Date: 2025-03-12DOI: 10.1177/00099228251323396
Cindy Villatoro, Ellen Henning, Rowena Ng, Marianna Kogut, Janna Steinberg, Belinda Chen, Calliope Holingue, Mary Leppert, Laura A Malone
{"title":"Enhancing Pediatric Long COVID Care Through Telementoring: Insights From an ECHO Program.","authors":"Cindy Villatoro, Ellen Henning, Rowena Ng, Marianna Kogut, Janna Steinberg, Belinda Chen, Calliope Holingue, Mary Leppert, Laura A Malone","doi":"10.1177/00099228251323396","DOIUrl":"10.1177/00099228251323396","url":null,"abstract":"<p><p>Long COVID affects a significant number of children, yet clinician knowledge gaps and limited access to specialized care hinder effective management. With fewer than 20 pediatric long COVID clinics in the United States, many families must travel long distances for care. To address these challenges, a pediatric long COVID ECHO (Extension for Community Healthcare Outcomes) program was developed to educate health care professionals on evidence-based care. The program engaged 94 participants from the United States and Canada via weekly tele-education sessions, recruited through word of mouth and professional listservs. Pre-surveys (41% response rate) and post-surveys (29% response rate) were sent to attendees. Participants reported statistically significant improvements in knowledge, confidence, competence, and self-efficacy (<i>P</i> < 0.001). This program represents a valuable initiative to facilitate timely interventions and empower primary care and community providers in diagnosing, treating, and managing long COVID in pediatric populations.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1209-1217"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143613768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seyit Ahmet Uçaktürk, Makbule Çöküş, Muharrem Bayram, Eda Mengen
{"title":"Initial Subcutaneous Insulin Requirement in Children With Newly Diagnosed Type 1 Diabetes.","authors":"Seyit Ahmet Uçaktürk, Makbule Çöküş, Muharrem Bayram, Eda Mengen","doi":"10.1177/00099228251379206","DOIUrl":"https://doi.org/10.1177/00099228251379206","url":null,"abstract":"<p><p>This study aimed to assess the factors affecting the daily subcutaneous insulin dose in children with newly diagnosed T1D. A retrospective file review of 85 children (≤18 years old) admitted to the hospital between 2020 and 2023 due to new onset T1D. Whereas total daily subcutaneous insulin dose (TDD) on the first day 1.3 ± 0.16 u/kg/day, it was 0.81 ± 0.28 u/kg/day on the last day. Total daily subcutaneous insulin dose on the first day was significantly higher in patients presenting with diabetic ketoacidosis (DKA) than in those presenting with ketosis and hyperglycemia (1.41 ± 0.14 u/kg/day and 1.19 ± 0.18 u/kg/day respectively). The three groups had similar TDD on the last day. The multiple linear regression analysis identified pH at admission and body weight as parameters affecting TDD. Our results support the high insulin requirement that continues after switching to subcutaneous treatment with the severity of acidosis. Therefore, subcutaneous insulin dose should be adjusted according to presentation characteristics.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"99228251379206"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}