Clinical Pediatrics最新文献_第10页

Multisystemic Inflammatory Syndrome in Children (MIS-C) With COVID-19 and Kidney Involvement: Poor Outcomes in a Case Series. 伴有 COVID-19 和肾脏受累的儿童多系统炎症综合征（MIS-C）：一个病例系列的不良结果。

IF 1 4区医学

Clinical Pediatrics Pub Date : 2024-08-09 DOI: 10.1177/00099228241272008

Nora S Alghamdi, Lujain Aletani, Ibrahim Sandokji, Hasan Aljefri, Khalid Alhasan, Mohammad A Shalaby, Jameela A Kari

{"title":"Multisystemic Inflammatory Syndrome in Children (MIS-C) With COVID-19 and Kidney Involvement: Poor Outcomes in a Case Series.","authors":"Nora S Alghamdi, Lujain Aletani, Ibrahim Sandokji, Hasan Aljefri, Khalid Alhasan, Mohammad A Shalaby, Jameela A Kari","doi":"10.1177/00099228241272008","DOIUrl":"https://doi.org/10.1177/00099228241272008","url":null,"abstract":"Multisystemic inflammatory syndrome (Mis-C) has emerged in May 2020 as a serious complication of coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). A total of 6 children presented to tertiary care hospitals with Mis-C, of which 5 (83%) have died during hospitalization. All included patients presented with respiratory symptoms (ranged from mild to severe acute respiratory distress syndrome) and gastrointestinal symptoms. Most of the patients are known to have medical illnesses. Pediatric Risk of Mortality (PRISM) IV score ranged from 3 to 87. All patients developed acidosis and varying stages of acute kidney injury and electrolyte disturbances. All were treated for coagulopathy, thrombocytopenia, bacterial infections as well as antiviral medications (either ritonavir or lopinavir). Most patients had chest X-ray changes either unilateral or bilateral lung changes. Multisystemic inflammatory syndrome is a rare, yet serious complication of SARS-CoV2 infection in children. Multisystem involvement should be anticipated and promptly treated.","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141912052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk Factors for Intravenous Immunoglobulin Non-responsiveness and Coronary Ectasia in Korean Patients With Kawasaki Disease. 韩国川崎病患者对静脉注射免疫球蛋白无反应和冠状动脉异位的风险因素

IF 1 4区医学

Clinical Pediatrics Pub Date : 2024-08-09 DOI: 10.1177/00099228241271897

Jung Min Park, Jae Hee Seol, Bongsic Yun, Donghwa Yang

{"title":"Risk Factors for Intravenous Immunoglobulin Non-responsiveness and Coronary Ectasia in Korean Patients With Kawasaki Disease.","authors":"Jung Min Park, Jae Hee Seol, Bongsic Yun, Donghwa Yang","doi":"10.1177/00099228241271897","DOIUrl":"https://doi.org/10.1177/00099228241271897","url":null,"abstract":"We aimed to determine the risk factors for non-responsiveness to intravenous immunoglobulin (IVIG) and coronary ectasia in Korean children with Kawasaki disease (KD) and compare the efficacy of previously published Japanese and Chinese risk scoring systems in the same cohort. We retrospectively reviewed 459 KD cases diagnosed from January 1, 2013, to December 31, 2022. Age (odds ratio [OR]: 0.983; 95% confidence interval [CI]: 0.968-0.999), change in extremities (OR: 3.308; 95% CI: 1.530-7.151), neutrophils (OR: 1.078; 95% CI: 1.049-1.108), and alanine aminotransferase (OR: 1.002; 95% CI: 1.000-1.004) were identified as independent risk factors for IVIG non-responsiveness, and age (OR: 0.945; 95% CI: 0.902-0.989), C-reactive protein (OR: 1.092; 95% CI: 1.004-1.188), and creatinine kinase (OR: 1.004; 95% CI: 1.001-1.006) were identified as independent risk factors for coronary ectasia. Among previously published risk scoring systems, the Egami (area under the receiver operating characteristics curve [AUC]: 0.695; 95% CI: 0.651-0.737) for IVIG non-responsiveness and the Tang score (AUC: 0.726; 95% CI: 0.578-0.874) for coronary ectasia showed the highest predictive value for our study cohort.","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141912055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reducing Capillary Leak Syndrome Mortality in Extremely Premature Infants: A Pilot Investigation. 降低极早产儿毛细血管渗漏综合征死亡率：试点调查

IF 1 4区医学

Clinical Pediatrics Pub Date : 2024-08-09 DOI: 10.1177/00099228241272037

Timothy J Boly, Michell M Lozano-Chinga, Melanie E Reyes-Hernandez, Timothy G Elgin, Zuhair Ballas, Jennifer R Bermick

引用次数: 0

Orthostatic Intolerance in Children With Long COVID Utilizing a 10-Minute Passive Standing Test. 利用 10 分钟被动站立测试研究长 COVID 儿童的直立性不耐受。

IF 1 4区医学

Clinical Pediatrics Pub Date : 2024-08-09 DOI: 10.1177/00099228241272053

Amanda K Morrow, Cindy Villatoro, Christina Kokorelis, Peter C Rowe, Laura A Malone

引用次数: 0

Serum Sickness and Serum Sickness-Like Reactions Presenting to Pediatric Hospital. 儿科医院出现的血清病和血清病样反应。