Clinical PediatricsPub Date : 2025-05-01Epub Date: 2024-08-14DOI: 10.1177/00099228241273420
Jing Sheng, Hao Zhang, Yalin Song, Hao Lou, Cuiping Wu, Changfu Hao, Ran Li, Genli Gao, Xiaomin Lou, Xian Wang
{"title":"Physical activity may attenuate psychological distress associated with different types of sedentary behaviors: a cross-sectional study of 10972 Chinese students.","authors":"Jing Sheng, Hao Zhang, Yalin Song, Hao Lou, Cuiping Wu, Changfu Hao, Ran Li, Genli Gao, Xiaomin Lou, Xian Wang","doi":"10.1177/00099228241273420","DOIUrl":"10.1177/00099228241273420","url":null,"abstract":"<p><p>The aim of the study was to investigate independent and joint associations of physical activity and sedentary behavior with psychological distress. In this cross-sectional study, all participants underwent a physical examination and questionnaire survey, including physical activity, sedentary behavior, and psychological distress. The rank-sum test was used to compare the distribution of psychological distress status among students with different characteristics, physical activity levels, and sedentary time. Logistic regression models were used to analyze the independent and joint association between physical activity, sedentary behavior, and psychological distress, stratified by age. The results of the rank sum test and logistic regression showed that students with more sedentary behavior and less physical activity were associated with higher psychological distress generally, but physical activity may attenuate the psychological distress relevant to non-screen-based sedentary behavior on weekdays in middle and high school students and screen-based sedentary behavior on weekends in all participants.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"494-508"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141981799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-05-01Epub Date: 2024-08-23DOI: 10.1177/00099228241274908
Christina Kokorelis, Carolyn Jenks, Peter C Rowe
{"title":"The Co-Occurrence of POTS and PPPD: A Pediatric Case Report.","authors":"Christina Kokorelis, Carolyn Jenks, Peter C Rowe","doi":"10.1177/00099228241274908","DOIUrl":"10.1177/00099228241274908","url":null,"abstract":"","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"461-464"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-05-01Epub Date: 2024-08-19DOI: 10.1177/00099228241273381
Gonzalo Mellado, Manuel Rodríguez, Diego Aragón-Caqueo, María Teresa Dossi, Paula Muñoz
{"title":"Non-scarring Bitemporal Asymptomatic Alopecia Unraveling a Sensitive Diagnosis.","authors":"Gonzalo Mellado, Manuel Rodríguez, Diego Aragón-Caqueo, María Teresa Dossi, Paula Muñoz","doi":"10.1177/00099228241273381","DOIUrl":"10.1177/00099228241273381","url":null,"abstract":"","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"598-602"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-05-01Epub Date: 2024-08-28DOI: 10.1177/00099228241272029
Yanshu Xie, Jingsi Luo, Jingzi Zhong, Dan Lan
{"title":"Clinical Diagnosis and Genetic Analysis of Children With Muscular Dystrophies.","authors":"Yanshu Xie, Jingsi Luo, Jingzi Zhong, Dan Lan","doi":"10.1177/00099228241272029","DOIUrl":"10.1177/00099228241272029","url":null,"abstract":"<p><p>More than 90% suspected muscular dystrophy (MD) can be confirmed with multiplex ligation-dependent probe amplification (MLPA) combined with targeted panel, although there are a few that cannot be identified. A total of 312 suspected MD patients were enrolled into the study. The MLPA combined with a targeted myopathy panel were performed. Patients with negative results were subjected to whole exome sequencing (WES), whole genome sequencing (WGS), and/or RNA sequencing (RNA-seq). A total of 275 cases were diagnosed as Duchenne/Becker muscular dystrophy (DMD/BMD) and 20 cases were other types of myopathy or nonmuscular diseases. Six female DMD/BMD patients suffered from varying degrees of typical DMD-like symptoms and 2 others were suspected to be gonadal mosaicism. The systematic application of WES, WGS, and/or RNA-seq highlighted the need for the detection of variants missed by the current standard diagnostic procedures. The identification of female patients and mosaic carriers was crucial to predict the risk of recurrence and allow for optimal genetic counseling.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"480-493"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142092474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-05-01Epub Date: 2024-09-01DOI: 10.1177/00099228241275033
Luana Andrade Macêdo, Fernanda Vilanova Nascimento Silva, Aline Santana Dosea, Fernando de Castro Araujo-Neto, Thaciana Dos Santos Alcântara, Lincoln Marques Cavalcante-Santos, Sílvia de Magalhães Simões, Divaldo Pereira de Lyra
{"title":"Perceptions of Children and Caregivers Regarding Asthma and Its Pharmacotherapy: A Qualitative Study.","authors":"Luana Andrade Macêdo, Fernanda Vilanova Nascimento Silva, Aline Santana Dosea, Fernando de Castro Araujo-Neto, Thaciana Dos Santos Alcântara, Lincoln Marques Cavalcante-Santos, Sílvia de Magalhães Simões, Divaldo Pereira de Lyra","doi":"10.1177/00099228241275033","DOIUrl":"10.1177/00099228241275033","url":null,"abstract":"<p><p>Asthma, when untreated, may lead to serious implications, especially in the pediatric population. Understanding the perceptions and needs of children and their caregivers may optimize asthma management. This study was aimed to analyze the perceptions of children and their caregivers regarding asthma and its pharmacotherapy. This is a qualitative study using 2 focus groups. We use the Bardin's content analysis. Three researchers made data cross-validation. As for results, the first focus group comprised 7 children who had uncontrolled asthma. The second group comprised 7 caregivers who were the children's mothers. Four categories emerged: living with asthma, impact of asthma, medications, and health care. Asthma and its pharmacotherapy significantly affect the daily activities of children and mothers. Thus, understand feelings and experiences of patients and caregivers, in addition to educational and welcoming interventions for families in asthma management may be carried out by health care professionals to minimize the damage caused by this disease.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"546-557"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-05-01Epub Date: 2024-09-28DOI: 10.1177/00099228241281126
An Hoai Duong
{"title":"Parents' Willingness to Vaccinate Their Children Aged From 6 Months to Under 5 Years With COVID-19 Vaccines.","authors":"An Hoai Duong","doi":"10.1177/00099228241281126","DOIUrl":"10.1177/00099228241281126","url":null,"abstract":"<p><p>Despite strides in vaccinating priority groups against COVID-19, children under 5 years in Vietnam are still under-immunized, emphasizing a significant gap in prioritization. This study aimed to assess parental willingness to vaccinate children aged 6 months to under 5 years against COVID-19 in Vietnam and identify influential factors affecting this willingness. Data were collected via a survey of 5960 parents/guardians between May and June 2022. Multinomial logistic regression was employed to analyze the impact of various factors on parents' willingness to vaccinate their children, alongside investigating reasons for reluctance or refusal and preferences for vaccine origins. Approximately 50.5%, 30.2%, and 19.3% of parents were willing, hesitant, and unwilling to vaccinate their children, respectively. Primary reasons for reluctance included concerns about vaccine safety, efficacy, and the severity of the pandemic. The most preferred vaccines originated in the United States. Factors significantly influencing willingness included parents' age, knowledge of COVID-19 and vaccines, residency, education, perception of information sufficiency, children's comorbidities, and family members' vaccination status. Promoting child vaccination habits can boost COVID-19 immunization rates. Targeting hesitancy among parents of children with comorbidities is crucial. Enhancing parental knowledge and leveraging fully vaccinated family members are effective strategies.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"570-582"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-05-01Epub Date: 2024-09-03DOI: 10.1177/00099228241278900
Patrick T Reeves, Taylor Meyers, Bailey Howard, Philip L Rogers, Benjamin Jack, Nathan T Kolasinski, Carolyn Sullivan Burklow, Steve Min, Cade M Nylund
{"title":"Potty Stools, a Pilot Study to Step Up the Management of Functional Constipation in Children.","authors":"Patrick T Reeves, Taylor Meyers, Bailey Howard, Philip L Rogers, Benjamin Jack, Nathan T Kolasinski, Carolyn Sullivan Burklow, Steve Min, Cade M Nylund","doi":"10.1177/00099228241278900","DOIUrl":"10.1177/00099228241278900","url":null,"abstract":"<p><p>Functional constipation (FC) comprises 30% of pediatric gastroenterology clinic visits. FC results from withholding behaviors that can be worsened by poor toileting posture. The use of a defecation posture modification device (DPMD)-a potty stool-has demonstrated benefit in adults. The aim of this study was to assess the risks and benefits of incorporating a DPMD as an adjunct to the FC treatment plan for children. Toilet-trained children aged ≥4 years meeting the Rome IV criteria for FC were enrolled and offered a DPMD at no cost and were followed for 4 months. There were no injuries or treatment-related adverse events reported by the 43 subjects who completed the study. Notably, 98% (n = 42) of respondents would recommend the DPMD to assist other children with FC. DPMD users showed a 33% reduction in fecal incontinence compared with 60% non-users. The DPMD represents a safe adjunct to incorporate into the FC management plan of children.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"558-563"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-05-01Epub Date: 2024-08-09DOI: 10.1177/00099228241271897
Jung Min Park, Jae Hee Seol, Bongsic Yun, Donghwa Yang
{"title":"Risk Factors for Intravenous Immunoglobulin Non-responsiveness and Coronary Ectasia in Korean Patients With Kawasaki Disease.","authors":"Jung Min Park, Jae Hee Seol, Bongsic Yun, Donghwa Yang","doi":"10.1177/00099228241271897","DOIUrl":"10.1177/00099228241271897","url":null,"abstract":"<p><p>We aimed to determine the risk factors for non-responsiveness to intravenous immunoglobulin (IVIG) and coronary ectasia in Korean children with Kawasaki disease (KD) and compare the efficacy of previously published Japanese and Chinese risk scoring systems in the same cohort. We retrospectively reviewed 459 KD cases diagnosed from January 1, 2013, to December 31, 2022. Age (odds ratio [OR]: 0.983; 95% confidence interval [CI]: 0.968-0.999), change in extremities (OR: 3.308; 95% CI: 1.530-7.151), neutrophils (OR: 1.078; 95% CI: 1.049-1.108), and alanine aminotransferase (OR: 1.002; 95% CI: 1.000-1.004) were identified as independent risk factors for IVIG non-responsiveness, and age (OR: 0.945; 95% CI: 0.902-0.989), C-reactive protein (OR: 1.092; 95% CI: 1.004-1.188), and creatinine kinase (OR: 1.004; 95% CI: 1.001-1.006) were identified as independent risk factors for coronary ectasia. Among previously published risk scoring systems, the Egami (area under the receiver operating characteristics curve [AUC]: 0.695; 95% CI: 0.651-0.737) for IVIG non-responsiveness and the Tang score (AUC: 0.726; 95% CI: 0.578-0.874) for coronary ectasia showed the highest predictive value for our study cohort.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"472-479"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141912055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-05-01Epub Date: 2024-08-20DOI: 10.1177/00099228241274915
Javier Arredondo Montero, Paula Ortolá Fortes, Carlos Bardají Pascual
{"title":"Back to Basics: A Clinical Medicine to Safeguard International Cooperation.","authors":"Javier Arredondo Montero, Paula Ortolá Fortes, Carlos Bardají Pascual","doi":"10.1177/00099228241274915","DOIUrl":"10.1177/00099228241274915","url":null,"abstract":"<p><p>The medical profession is currently undergoing a significant transformation. In recent decades, we have seen the emergence and implementation of new diagnostic tools, therapeutic targets, and technical procedures that have revolutionized our clinical practice. These resources have undoubtedly improved patient outcomes but have also led to excessive reliance on technology. This overreliance can limit the new generation's capacity to provide humane and comprehensive patient care and develop critical thinking skills. In this article, we reflect on the urgent impact of this trend on pediatric international cooperation and propose workable solutions to this problem. We stress the importance of maintaining a patient-centered approach in the face of these technological advancements, as it ensures that the patient's needs remain at the forefront of our practice.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"594-597"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}