Clinical Pediatrics最新文献

A Rare Manifestation of Excessive Cow's Milk Consumption.

IF 1 4区医学

Clinical Pediatrics Pub Date : 2025-04-04 DOI: 10.1177/00099228251333210

April Butler, David Gutglass, Karen Kim Jo Yaphockun

引用次数: 0

Safety of Petroleum-Based Emollients in Pediatric Atopic Dermatitis.

IF 1 4区医学

Clinical Pediatrics Pub Date : 2025-04-01 DOI: 10.1177/00099228251331443

Helana Ghali, Amanda Krenitsky, Sharon E Albers

引用次数: 0

A Cross-Sectional Retrospective Review of Neuropsychiatric Comorbidities in Children With Non-Alcoholic Fatty Liver Disease.

IF 1 4区医学

Clinical Pediatrics Pub Date : 2025-03-27 DOI: 10.1177/00099228251330113

Katherine F Sweeny, Christine K Lee, Paul D Mitchell, Shavonne Osiakwan, Cosette Scott, Maureen M Jonas

{"title":"A Cross-Sectional Retrospective Review of Neuropsychiatric Comorbidities in Children With Non-Alcoholic Fatty Liver Disease.","authors":"Katherine F Sweeny, Christine K Lee, Paul D Mitchell, Shavonne Osiakwan, Cosette Scott, Maureen M Jonas","doi":"10.1177/00099228251330113","DOIUrl":"https://doi.org/10.1177/00099228251330113","url":null,"abstract":"This single-center cross-sectional retrospective chart review sought to define the prevalence of neuropsychiatric (NP) disorders among children with non-alcoholic fatty liver disease (NAFLD) compared to the general population. The prevalence rate of NP disorders was determined at diagnosis among children evaluated from 2006 to 2016. The NP disorder prevalence rates were compared to those reported in the 2016 National Survey of Children's Health (NSCH). 24.3% of 254 children with NAFLD reported to have at least 1 NP disorder compared to 16.9% of those in NSCH (relative risk [RR] = 1.44; P < .0001). More children had intellectual disability (ID) (4.5% vs 0.8%; RR = 5.43, P < .0001), depression (3.9% vs 2.2%; RR = 1.82, P = .0009), or autism spectrum disorder (ASD) (3.3% vs 2.0%; RR = 1.67, P = .047) in the Boston Children's Hospital (BCH) NAFLD cohort. The prevalence of 1 NP disorder was 29.4% in our cohort compared to 22.3% in NSCH (RR = 1.32; P = .007). Children with NAFLD have a higher rate of NP disorders compared to the general population.","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"99228251330113"},"PeriodicalIF":1.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple Pulmonary Nodules, Cough, and Sore Throat in a Child.

IF 1 4区医学

Clinical Pediatrics Pub Date : 2025-03-25 DOI: 10.1177/00099228251326477

Ante Vidović, Ivana Radoš, Renata Vrsalović, Srđan Roglić, Nada Rajačić, Mandica Vidović

引用次数: 0

Primary Care Clinician Perspectives on Medication Prescribing for Child Mental Health Concerns.

IF 1 4区医学

Clinical Pediatrics Pub Date : 2025-03-25 DOI: 10.1177/00099228251328142

Cody A Hostutler, Noelle Wolf, Katrice Stallworth, Rachel Herbst, Kathryn W Hoffses, Julie Pajek, David Curtis, Jennifer A Mautone, Andrew R Riley, Jeffrey D Shahidullah

{"title":"Primary Care Clinician Perspectives on Medication Prescribing for Child Mental Health Concerns.","authors":"Cody A Hostutler, Noelle Wolf, Katrice Stallworth, Rachel Herbst, Kathryn W Hoffses, Julie Pajek, David Curtis, Jennifer A Mautone, Andrew R Riley, Jeffrey D Shahidullah","doi":"10.1177/00099228251328142","DOIUrl":"https://doi.org/10.1177/00099228251328142","url":null,"abstract":"This study describes the frequency and comfort of pediatric primary care clinicians (PCCs) as it relates to initiating, continuing, and stopping medications for attention-deficit/hyperactivity disorder (ADHD), anxiety/depression, and sleep problems across age groups (≤5 years, 6-12, and 13+). Primary care clinicians (N = 148) within an integrated primary care national research consortium participated in an anonymous online survey including questions examining practice settings, provider characteristics, prescribing frequency, and prescribing comfort. Results indicate that comfort and prescribing practices vary by patient age, practice setting, provider experience, and presenting diagnoses. Primary care clinicians generally felt more comfortable prescribing for school-age children and older and prescribing for ADHD-related concerns. Primary care clinicians appeared similarly comfortable starting, maintaining, and stopping medications. Rural PCCs reported greater comfort initiating and managing medication. Results highlight the need for ongoing training and support for PCCs in managing common childhood mental health conditions. Implications for establishing collaborative infrastructure support and team-based care are discussed.","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"99228251328142"},"PeriodicalIF":1.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Link Between Respiratory Syncytial Virus-Induced Lower Respiratory Tract Infection and Type 2 Inflammation in Asthma.

IF 1 4区医学

Clinical Pediatrics Pub Date : 2025-03-24 DOI: 10.1177/00099228251321597

Bei Ye, Shu Teng, Lu Zhan

{"title":"The Link Between Respiratory Syncytial Virus-Induced Lower Respiratory Tract Infection and Type 2 Inflammation in Asthma.","authors":"Bei Ye, Shu Teng, Lu Zhan","doi":"10.1177/00099228251321597","DOIUrl":"https://doi.org/10.1177/00099228251321597","url":null,"abstract":"Objective: To investigate the relationship between the type 2 inflammatory response associated with asthma and lower respiratory tract infection (LRTI) caused by respiratory syncytial virus (RSV).Methods: Sixty-seven children with RSV infection hospitalized in our hospital from October 2023 to December 2023 and 27 healthy children undergoing medical examination were included. The study population was divided into the RSV LRTI group (n = 67) and the control group (n = 27). Interleukin-13 (IL-13), serum total immunoglobulin E (IgE), mucin 5AC (MUC5AC), and blood eosinophil count (EOS) were tested and compared between the two groups. The presence or absence of specificity between the two groups was analyzed using the rank sum test and subject operating characteristic curves (Receiver Operating Characteristic curves, ROC curves).Results: The levels of IL-13, IgE, MUC5AC, and EOS were higher in children with RSV LRTI compared to healthy children. These differences were statistically significant (P < .05). The ROC curve analysis results showed that IL-13, IgE, MUC5AC, and EOS predicted type 2 inflammation with areas under the curve of 0.687, 0.762, 0.764, and 0.646, respectively.Conclusion: A type 2 inflammatory response associated with asthma may be observed after RSV-induced LRTIs.","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"99228251321597"},"PeriodicalIF":1.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness and Safety of High-Dose Oral Phenobarbital in Children With Recurrent and Treatment-Refractory Seizures.

IF 1 4区医学

Clinical Pediatrics Pub Date : 2025-03-24 DOI: 10.1177/00099228251328136

Muhittin Bodur, Rabia Tutuncu Toker

{"title":"Effectiveness and Safety of High-Dose Oral Phenobarbital in Children With Recurrent and Treatment-Refractory Seizures.","authors":"Muhittin Bodur, Rabia Tutuncu Toker","doi":"10.1177/00099228251328136","DOIUrl":"https://doi.org/10.1177/00099228251328136","url":null,"abstract":"In this study, we applied high-dose oral phenobarbital (PB) to children with recurrent and treatment-refractory seizures or recurrent status epilepticus and evaluated the effectiveness and safety of this treatment. We retrospectively reviewed patients' medical records who received oral high-dose PB treatment between January 2019 and July 2024. In this study, recurrent and treatment-refractory seizures was defined as the persistence of daily epileptic seizures or recurrent attacks of status epilepticus despite treatment with oral antiepileptic drugs or continuous intravenous midazolam therapy. High-dose oral PB therapy was performed on 11 patients (7 females and 4 males). The median age at the onset of epilepsy was 2 months (range: 0.06-132 months). The underlying disorders or comorbidity were genetic disorders (1q14 del, compound heterozygous for the PNKP gene, Wolf-Hirschhorn syndrome, ring chromosome 14 syndrome) in 4 patients, cerebral palsy in 2 patients, metabolic disorders (Zellweger syndrome, pyridoxine-dependent epilepsy) in 2 patients, traumatic brain injury and hypoxia, hemimegalencephaly, and ataxia and intellectual disability in 1 patient. The median age at initiation of high-dose PB therapy was 11 months (range: 2-203 months). The maximal dose of PB ranged from 6 to 14.7 mg/kg/d (median: 10 mg/kg/day). The maximal serum PB levels ranged from 33 to 56 µg/mL (median: 44 µg/mL). We evaluated the effectiveness of this treatment as follows: \"effective\" represented more than 50% seizure reduction, \"ineffective\" represented less than 50% seizure reduction, and \"exacerbation\" represented an increase in seizure frequency. In 7 of the 11 patients (63.6%), oral high-dose PB therapy was effective and was transiently effective in the other 4 patients. Adverse effects were noted in 6 patients (54.5%) during high-dose oral PB therapy: drowsiness in 5 patients and mild elevations in transaminases in 2 patients.","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"99228251328136"},"PeriodicalIF":1.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Longitudinal Study on the Influence of Parental Interaction on Preschool Children's Cognitive Development: A Retrospective Analysis.

IF 1 4区医学

Clinical Pediatrics Pub Date : 2025-03-20 DOI: 10.1177/00099228251322607

Yanli Qin, Qinchun Yu, Tian Qiu

{"title":"A Longitudinal Study on the Influence of Parental Interaction on Preschool Children's Cognitive Development: A Retrospective Analysis.","authors":"Yanli Qin, Qinchun Yu, Tian Qiu","doi":"10.1177/00099228251322607","DOIUrl":"https://doi.org/10.1177/00099228251322607","url":null,"abstract":"To investigate the impact of parental interaction on cognitive development in preschool children, a study was conducted involving 198 preschool children selected between June 2021 and January 2022. These children were divided into a control group and an observation group based on their participation in parent-child interaction education. The propensity score matching method was employed to ensure baseline equivalence between the 2 groups. Post-matching, comparisons were made regarding language ability, social communication skills, social life skills, intelligence, and neurodevelopment. No significant differences were observed between the groups at baseline. Following the intervention, the observation group demonstrated significantly higher scores in language ability (P < .05), communication and life skills (P < .05), as well as intelligence and neurodevelopment, compared with the control group (P < .05). These findings suggest that parental interaction interventions can effectively enhance language abilities, social skills, social life skills, intelligence, and neurodevelopment in preschool children, and thus, are recommended for adoption.","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"99228251322607"},"PeriodicalIF":1.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subacute Acquired Chorea in a Child: An Unexpected Co-occurrence.

IF 1 4区医学

Clinical Pediatrics Pub Date : 2025-03-17 DOI: 10.1177/00099228251325544

Mark Krongold, Seth D Marks, Michael S Salman

引用次数: 0

Designing a Better Health System: Patient Perspectives on Gender Inclusive Care.

IF 1 4区医学

Clinical Pediatrics Pub Date : 2025-03-17 DOI: 10.1177/00099228251325448

Debra Yeh, David J Inwards-Breland, Tay L Richardson, Maja Marinkovic, Bixby Marino-Kibbee, Aarti Patel, Erin Stucky Fisher, Lauren Gist, Kyung E Rhee

{"title":"Designing a Better Health System: Patient Perspectives on Gender Inclusive Care.","authors":"Debra Yeh, David J Inwards-Breland, Tay L Richardson, Maja Marinkovic, Bixby Marino-Kibbee, Aarti Patel, Erin Stucky Fisher, Lauren Gist, Kyung E Rhee","doi":"10.1177/00099228251325448","DOIUrl":"https://doi.org/10.1177/00099228251325448","url":null,"abstract":"Our study explored perspectives of transgender and non-binary (TNB) patients regarding gender-inclusive care at our medical center. Thirty participants (13-21 years old) completed semi-structured interviews and demographic surveys. Surveys were analyzed using descriptive statistics, and interviews were analyzed using thematic analysis. Key themes contributing to positive experiences were: (1) personnel with experience caring for TNB youth, (2) Lesbian, Gay, Bisexual, Transgender, Queer, Intersex, Asexual (LGBTQIA) identified health care team members, (3) visible improvements made over time, (4) provider and staff advocacy, and (5) parent advocacy. Areas for improvement were: (1) training on use of pronouns, gender-affirming terminology, and exam techniques, (2) accurate display of name and pronouns in the electronic medical record and patient labels throughout clinical settings, and (3) more LGBTQIA-inclusive décor and resources. While improvements were recognized, participants identified persistent gaps. Multilevel advocacy and standards set by accrediting bodies can be the next steps in ensuring quality care for TNB patients.","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"99228251325448"},"PeriodicalIF":1.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0