{"title":"Effective <i>Pseudomonas aeruginosa</i> Eradication in Cystic Fibrosis: Multicenter Study.","authors":"Aynur Guliyeva, Cansu Yilmaz Yegit, Muruvvet Yanaz, Mine Kalyoncu, Merve Selçuk Balcı, Seyda Karabulut, Almala Pınar Ergenekon, Gamze Tastan, Burcu Uzunoglu, Hüseyin Arslan, Hakan Yazan, Gülay Bas Bilgin, Ebru Köstereli, Ayse Ayzıt Kılınc Sakallı, Erkan Cakır, Saniye Girit, Zeynep Seda Uyan, Yasemin Gokdemir, Ela Erdem Eralp, Fazilet Karakoc, Bulent Karadag","doi":"10.1177/00099228251351699","DOIUrl":"10.1177/00099228251351699","url":null,"abstract":"<p><strong>Background: </strong>Pseudomonas aeruginosa (PA) eradication is crucial in cystic fibrosis (CF) management. At our center, the success rate was 21.6%, prompting a revised eradication protocol to evaluate a new regimen.</p><p><strong>Methods: </strong>Cystic fibrosis patients with first-time PA detection were included. Nonmucoid PA cases received oral ciprofloxacin (3 weeks) and inhaled tobramycin (1 month). For mucoid PA or failed eradication, ciprofloxacin (3 weeks) and extended nebulized therapy (3 months, alternating tobramycin/colistin) were used. Intravenous antibiotics were given to unwell patients.</p><p><strong>Results: </strong>Among 109 CF patients (median age: 6 years), 79 (72.5%) achieved successful eradication. Oral ciprofloxacin and tobramycin inhalation were used in 66 patients (60.6%), extended nebulized therapy in 26 (23.8%), and intravenous antibiotics in 17(15.6%).</p><p><strong>Conclusion: </strong>The revised protocol achieved a high PA eradication rate in CF patients. Adapting treatment regimens based on PA characteristics and patient condition can optimize outcomes and improve CF management.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1581-1588"},"PeriodicalIF":0.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-11-01Epub Date: 2025-06-08DOI: 10.1177/00099228251345199
Sinem Kars, Esra Aki
{"title":"Playfulness of Preschool-Aged Children With Autism in a Sensory Integration Room.","authors":"Sinem Kars, Esra Aki","doi":"10.1177/00099228251345199","DOIUrl":"10.1177/00099228251345199","url":null,"abstract":"<p><p>Playfulness can be determined by evaluation for the presence of 3 elements: intrinsic motivation, internal control, and the freedom to suspend reality. Playfulness may be affected by the child's physical, social, and cognitive skills and the physical, social, and cultural aspects of the play environment. Therefore, we aimed to investigate the playfulness of children with autism in a sensory integration room. Thirty-six children with autism, with a mean (SD) age of 62.1 (7.1) months, participated. Demographic Information Questionnaire and Turkish version of Test of Playfulness were used. The playfulness of the children with autism were analyzed according to children's gender, age and birth order, parents' age, education level and employment status, family income, and number of siblings. The playfulness is related to the father's education level (<i>r</i> = -0.534, <i>P</i> < .01), the mother's employment status (<i>r</i> = 0.335, <i>P</i> < .05) and family income (<i>r</i> = -0.469, <i>P</i> < .01). Implications are discussed and suggestions for future research are formulated.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1538-1548"},"PeriodicalIF":0.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-11-01Epub Date: 2025-06-24DOI: 10.1177/00099228251343941
Hwa-Mi Yang, Hye-Ryoung Kim, Hyunsuk An
{"title":"Exploring Information, Motivation, and Behavioral Skills on Childhood Obesity Through Focus Group Interviews With Parents and Children.","authors":"Hwa-Mi Yang, Hye-Ryoung Kim, Hyunsuk An","doi":"10.1177/00099228251343941","DOIUrl":"10.1177/00099228251343941","url":null,"abstract":"<p><p>This study explored the perceptions and experiences of children with obesity and their parents regarding childhood obesity based on the Information-Motivation-Behavioral Skills model. This qualitative study used focus group interviews with 20 participants (10 children with obesity or overweight, and 10 of their parents) to explore their information, motivation, and behavioral skills regarding childhood obesity. Participants displayed significant knowledge gaps regarding the causes and consequences of childhood obesity, necessitating accurate information dissemination. Motivations for addressing obesity individual motivations, such as health concerns, appearance, self-esteem, and social motivations encompassing personal experiences, peer influence, family dynamics, and the importance of positive role models. Parents and children demonstrated various behavioral skills to combat obesity, including portion control and engagement in physical activities. However, failures at both individual and environmental levels were identified, highlighting challenges in maintaining healthy habits. Addressing these challenges through tailored strategies and supportive environments is crucial for effective obesity management.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1511-1521"},"PeriodicalIF":0.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-11-01Epub Date: 2025-07-08DOI: 10.1177/00099228251354917
Madeline Simone, Annalise Bowen, Eric McGrath, Laura Benjamins, Elizabeth Secord
{"title":"Vaccine Acceptance Among Youth Living With HIV in Detroit.","authors":"Madeline Simone, Annalise Bowen, Eric McGrath, Laura Benjamins, Elizabeth Secord","doi":"10.1177/00099228251354917","DOIUrl":"10.1177/00099228251354917","url":null,"abstract":"","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1501-1504"},"PeriodicalIF":0.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Racial and Gender Disparities in Nasal Foreign Bodies in Pediatric Patients: A Decade-Long Analysis of U.S. Emergency Department Presentations.","authors":"Abdurrahman Al-Awady, Avanish Yendluri, Krisna Maddy, Shazli Elshazali, Ryan Sicard, Alfred-Marc Iloreta, Satish Govindaraj, Aldo Londino","doi":"10.1177/00099228251348695","DOIUrl":"10.1177/00099228251348695","url":null,"abstract":"<p><p>This study is a comprehensive epidemiological assessment of nasal foreign bodies (NFB) in pediatric patients, focusing on racial and gender disparities in incidence and outcomes. Pediatric NFB case data in children aged 0 to 12 was collected from The National Electronic Injury Surveillance System (NEISS) spanning 2012-2021. Emergency room disposition was classified into treatment and release, hospitalization, and leaving against medical advice. Chi-square analysis was used to assess variations. Incidence of NFBs was significantly higher in African American Children (<i>P</i> < .05) and in female patients, who were also less likely to be admitted and more likely to leave against medical advice (<i>P</i> < .05). Disposition data similarly unveiled African American and Asian American children were less likely to be admitted and more likely to leave against medical advice (<i>P</i> < .05). The observed disparities emphasize the imperative for community-specific interventions and spotlight potential systemic biases warranting further investigation in health care delivery.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1598-1605"},"PeriodicalIF":0.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144282687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-11-01Epub Date: 2025-06-16DOI: 10.1177/00099228251349259
Tomonori Sunakawa, Sota Iwatani, Akiko Yokoi, Tadashi Hatakeyama, Seiji Yoshimoto
{"title":"Growth Restriction Beginning in Early Infancy Among Survivors of Congenital Diaphragmatic Hernia: A Single-Center Experience.","authors":"Tomonori Sunakawa, Sota Iwatani, Akiko Yokoi, Tadashi Hatakeyama, Seiji Yoshimoto","doi":"10.1177/00099228251349259","DOIUrl":"10.1177/00099228251349259","url":null,"abstract":"<p><p>A significant number of congenital diaphragmatic hernia (CDH) survivors experience growth restriction (GR), but the timing of its onset is not well studied. This single-center retrospective study evaluated the frequency of GR at specific postnatal ages and associated risk factors. We reviewed charts of prenatally diagnosed CDH patients delivered between 2011 and 2020, with follow-up until December 2022. Body height and weight Z-scores were assessed at 1, 2, 3, 6, 12, 18, and 36 months of age. GR, defined as a Z-score below -2.0, was observed in 32%, 63%, 50%, 50%, 48%, 42%, and 24% of patients at these ages, respectively. Persistent GR up to 6 months was associated with lower birth weights, pulmonary vasodilator use at discharge, and asthma after discharge. GR begins in early infancy in CDH survivors but improves over time with catch-up growth, highlighting the need for long-term growth monitoring and nutritional/respiratory support after discharge.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1606-1612"},"PeriodicalIF":0.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-11-01Epub Date: 2025-06-16DOI: 10.1177/00099228251348311
David J Sas, Imad Absah, Sean M Phelan, Avni Y Joshi, Ana L Creo, Supriya Behl, Kristine T Hanson, Seema Kumar
{"title":"The Association Between Physician Demographics on Patient Satisfaction Survey Results in Pediatrics: A Role for Implicit Bias?","authors":"David J Sas, Imad Absah, Sean M Phelan, Avni Y Joshi, Ana L Creo, Supriya Behl, Kristine T Hanson, Seema Kumar","doi":"10.1177/00099228251348311","DOIUrl":"10.1177/00099228251348311","url":null,"abstract":"<p><p>We assessed associations of pediatrician demographic characteristics with patient satisfaction (PS) scores. We performed a retrospective analysis of PS scores among pediatricians at a single academic institution and their associations with individual demographic features including gender, race, and geographic location of medical school education. We analyzed PS survey results for 153 pediatricians, 48.4% of whom were female. Males received higher scores in 4 out of 10 questions including \"Likelihood of your recommending this care provider to others\" (<i>P</i> = .007). We observed similar findings for white pediatricians compared to Black, Indigenous, and People of Color (BIPOC) (<i>P</i> = .033) and US medical school graduates compared to international school graduates (<i>P</i> = .044). Overall, we observed that pediatricians who are female, BIPOC, or international medical school graduates receive lower PS scores than their counterparts. The impact of potential survey responder bias should be acknowledged when interpreting PS scores for pediatricians.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1567-1580"},"PeriodicalIF":0.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does Vitamin D Deficiency Contribute to Growing Pains? A Case-Control Study.","authors":"Isha Jain, Abinaya K, Nikita Agarwal, Snehamayee Nayak, Atul Jindal","doi":"10.1177/00099228251379209","DOIUrl":"https://doi.org/10.1177/00099228251379209","url":null,"abstract":"<p><p>Growing pains (GPs) are non-inflammatory pain syndromes affecting children aged 4 to 14 years. This case-control study aims to investigate the role of vitamin D deficiency in GP development. The study was conducted for 6 months. Healthy children without a history of GP were recruited as control subjects. Serum concentrations of calcium, phosphate, and alkaline phosphatase were measured. Vitamin D3 supplementation was administered to those identified with deficient or insufficient 25-hydroxyvitamin D (25-OHD). A total of 95.6% of the GP group and 93.3% of the control group had insufficient or deficient 25-OHD levels. No significant correlations for serum calcium, serum phosphate, and alkaline phosphatase with 25-OHD level in either group. Children with sufficient 25-OHD also experienced similar reduction in pain as those who received supplementation. The study found no significant difference in vitamin D levels between children with GP and those without.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"99228251379209"},"PeriodicalIF":0.7,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}