Andrés Barradas-Cervantes, Esther Moreno-Cabrera, Marco A Morales-Pérez
{"title":"Metabolic Profile and Clustering of Metabolic Syndrome Components in Children and Adolescents With Overweight and Obesity Attending Secondary Care in Mexico: A Single-Center Cross-Sectional Study.","authors":"Andrés Barradas-Cervantes, Esther Moreno-Cabrera, Marco A Morales-Pérez","doi":"10.1177/00099228261490957","DOIUrl":"https://doi.org/10.1177/00099228261490957","url":null,"abstract":"<p><p>This single-center cross-sectional study described the metabolic profile and clustering of metabolic syndrome components in 202 children and adolescents aged 10 to 16 years with overweight or obesity attending secondary care in Mexico. Metabolic syndrome was defined according to International Diabetes Federation criteria. Abdominal obesity was highly prevalent (88.6%), followed by low high-density lipoprotein cholesterol (52.5%) and hypertriglyceridemia (43.1%), whereas elevated fasting glucose and blood pressure were less frequent. Overall, 37.1% met the criteria for metabolic syndrome, and 38.1% presented 3 or more concurrent components, indicating substantial cardiometabolic clustering. Increasing component burden was associated with higher body mass index (BMI)-for-age <i>z</i>-scores, alanine aminotransferase, and uric acid levels. In ordinal logistic regression, older age and higher BMI-for-age <i>z</i>-score were independently associated with greater component burden, whereas sex and pubertal stage were not. These findings indicate a high burden of cardiometabolic abnormalities not fully captured by a dichotomous diagnosis, underscoring the need for comprehensive metabolic assessment in routine pediatric practice.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"99228261490957"},"PeriodicalIF":0.8,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2026-10-01Epub Date: 2026-05-21DOI: 10.1177/00099228261452841
Sema Kaya Bozkurt, Gonca Karayagiz Muslu
{"title":"The Relationship Between Psychological Resilience and Stress Levels of Mothers Whose Premature Babies Are Hospitalized in Neonatal Intensive Care Unit.","authors":"Sema Kaya Bozkurt, Gonca Karayagiz Muslu","doi":"10.1177/00099228261452841","DOIUrl":"10.1177/00099228261452841","url":null,"abstract":"<p><p>Having a premature infant hospitalized in the neonatal intensive care unit (NICU) is a highly stressful experience for mothers and may affect their psychological well-being. Psychological resilience is considered an important factor that may help mothers cope with the emotional challenges of the NICU environment. This study aimed to examine the relationship between psychological resilience and stress levels among mothers of premature infants hospitalized in the NICU. This descriptive, correlational, cross-sectional study was conducted with 187 mothers whose premature infants were hospitalized in an NICU. Data were collected using a Personal Information Form, the Psychological Resilience Scale for Adults, and the Neonatal Intensive Care Unit Parental Stress Scale. Mothers experienced notable levels of stress related to their infants' hospitalization. A significant negative association was identified between maternal stress and several dimensions of psychological resilience, including self-perception, future perception, family cohesion, and structural style. Strengthening psychological resilience through psychosocial support programs may help reduce maternal stress and support maternal well-being during the NICU hospitalization period.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1152-1163"},"PeriodicalIF":0.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147980800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2026-10-01Epub Date: 2026-06-27DOI: 10.1177/00099228261463464
Tsoline Kojaoghlanian, Katja Anuth, Katheryn Cireseanu, Areeba Qazi, Jeremy Silverstein, Maria Bhatti, Rabia Agha
{"title":"Pediatric Invasive Group A Streptococcus Characteristics Before, During, and After COVID-19.","authors":"Tsoline Kojaoghlanian, Katja Anuth, Katheryn Cireseanu, Areeba Qazi, Jeremy Silverstein, Maria Bhatti, Rabia Agha","doi":"10.1177/00099228261463464","DOIUrl":"10.1177/00099228261463464","url":null,"abstract":"<p><p>Pediatric invasive Group A Streptococcus (iGAS) infections two years before, during, and a year after the Coronavirus Disease 2019 (COVID-19) pandemic were analyzed in an urban hospital in the Northeastern United States. Invasive GAS was diagnosed in 38 patients. There were as many infected children post-COVID as in the prior 4.5 years combined. The post-pandemic surge was most striking in late spring. The median age was youngest during the post-pandemic year at 2.3 years. During and after the pandemic, about half the children had concurrent virus detection, and two-thirds had no known chronic comorbidities, highlighting <i>Streptococcus pyogenes'</i> potential for significant morbidity in healthy and young children. The spectrum of iGAS disease manifestations was similar among the 3 time periods, with soft tissue infections predominating overall. Of post-pandemic GAS isolates, 67% were <i>emm</i>1 and 33% were <i>emm</i>12. Preventive efforts of this grave disease at all ages should continue.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1268-1273"},"PeriodicalIF":0.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148338192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2026-10-01Epub Date: 2026-06-30DOI: 10.1177/00099228261462810
Rachel E Moss, Jan Fune, Catherine McDonough, Shubhi Kaushik, Sandeep Gangadharan
{"title":"Effect of Preferred Language on Pediatric Rapid Response Activation and Subsequent Intensive Care Utilization.","authors":"Rachel E Moss, Jan Fune, Catherine McDonough, Shubhi Kaushik, Sandeep Gangadharan","doi":"10.1177/00099228261462810","DOIUrl":"10.1177/00099228261462810","url":null,"abstract":"<p><p>Health care disparities stemming from language discordance have been well established, leading to increased morbidity and mortality. We sought to examine the effect of patient preferred language on time to rapid response activation and subsequent intensive care utilization. We sought to evaluate the association between patient preferred language and time to rapid response (RR) activation, intensive care unit (ICU) transfer rate, and intensive care utilization in a quaternary pediatric hospital. We conducted a retrospective observational study of pediatric patients with rapid response activation from January 2020 to June 2023. Demographic and clinical data, including time to rapid response, ICU transfers, and use of mechanical ventilation, non-invasive ventilation, and vasoactive support, were analyzed. Statistical comparisons were performed between English-speaking and language other than English (LOE) patients, with subgroup analyses for Spanish-speaking patients. Of 374 unique patients, 25% were using LOE. Time to rapid response activation was not significantly different between language groups. However, Spanish-speaking patients were more likely to be transferred to the ICU (<i>P</i> = .0047) and had longer hospital stays (10 vs 7 days, <i>P</i> = .0425). While language preference did not impact time to rapid response activation, Spanish-speaking patients had increased ICU transfers and prolonged hospital stays. These findings highlight the need for improved language-concordant care to mitigate disparities in pediatric critical care outcomes.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1260-1267"},"PeriodicalIF":0.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148351126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2026-10-01Epub Date: 2026-06-28DOI: 10.1177/00099228261460362
Faith Collins, Emily Moya, Marcos S Rojas-Pino, Michelle Zuniga-Hernandez, Faaizah Arshad, Ruth Feng, Ellen Y Wang, Samuel T Rodriguez, Christian Jackson, Thomas J Caruso
{"title":"Virtual Reality Education for Hospitalized Pediatric Patients Improves Intrinsic Motivation: A Prospective, Randomized Crossover Study.","authors":"Faith Collins, Emily Moya, Marcos S Rojas-Pino, Michelle Zuniga-Hernandez, Faaizah Arshad, Ruth Feng, Ellen Y Wang, Samuel T Rodriguez, Christian Jackson, Thomas J Caruso","doi":"10.1177/00099228261460362","DOIUrl":"10.1177/00099228261460362","url":null,"abstract":"<p><p>Hospitalized children experience educational disruption and reduced motivation during prolonged admissions. Despite the availability of in-hospital schools, many cannot participate due to illness severity or isolation precautions. This pragmatic, randomized crossover trial evaluated whether bedside virtual reality (VR) lessons improve intrinsic motivation among inpatients aged 5 to 25 years unable to attend the hospital school. Participants completed both VR-based educational sessions and standard of care (SOC) conditions on consecutive days. The primary outcome was intrinsic motivation, with secondary outcomes including educational self-efficacy, well-being, self-esteem, and parental experience. Of 156 enrolled patients, 100 were analyzed (mean age 11.5 [SD = 4.1 years]; 43.9% female). Intrinsic motivation scores were higher in the VR condition than SOC (<i>P</i> = .0048), and parental satisfaction was also greater (<i>P</i> = .0008). Bedside VR education represents a feasible, acceptable, and scalable adjunct to inpatient learning, supporting intrinsic motivation and caregiver satisfaction during hospitalization.<b>Trial Registration:</b> ClinicalTrials.gov NCT05725395, date first registered November 22, 2022.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1249-1259"},"PeriodicalIF":0.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148344019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2026-10-01Epub Date: 2026-07-15DOI: 10.1177/00099228261466899
Victor C Strasburger, Donald Shifrin, Marjorie Hogan
{"title":"Where the Recent AAP Policy on Digital Media Falls Short.","authors":"Victor C Strasburger, Donald Shifrin, Marjorie Hogan","doi":"10.1177/00099228261466899","DOIUrl":"10.1177/00099228261466899","url":null,"abstract":"","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1213-1215"},"PeriodicalIF":0.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148444808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2026-10-01Epub Date: 2026-05-26DOI: 10.1177/00099228261452213
Kathryn W Holmes, Juliana Sarwary, Sheila Markwardt, Monique Bohun, Christina Ronai, Jennifer H Huang, Erin Madriago
{"title":"Clinical Significance of a New Z-Score Calculator in Pediatric Patients With Kawasaki Disease.","authors":"Kathryn W Holmes, Juliana Sarwary, Sheila Markwardt, Monique Bohun, Christina Ronai, Jennifer H Huang, Erin Madriago","doi":"10.1177/00099228261452213","DOIUrl":"10.1177/00099228261452213","url":null,"abstract":"<p><p>This study examined the real-world impact of simultaneous dual Z-score reporting on the interpretation of coronary dilation in Kawasaki disease (KD). Two widely used reference systems exist for evaluating coronary artery dimensions in children: Boston Children's Hospital (Boston) and Pediatric Heart Network (PHN). We retrospectively reviewed KD echocardiograms performed at a single institution between January 2019 and November 2021; 47 KD patients were included. The PHN Z-scores for the left main coronary artery (LMCA) and left anterior descending (LAD) were larger than those of Boston, resulting in 15% of LAD and 13% of LMCA measurements classified as dilated by PHN but normal by Boston. Among discordant echocardiograms, cardiologists were evenly split on which system was cited, with 2 incomplete KD diagnoses confirmed solely on LAD dilation identified by PHN. Coronary normalization took a mean of 33 days by PHN vs 12 days by Boston. Simultaneous dual reporting introduces clinically meaningful discordance, warranting guideline standardization.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1137-1142"},"PeriodicalIF":0.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148027768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2026-10-01Epub Date: 2026-06-25DOI: 10.1177/00099228261452276
Begüm Avcı, Gönül Parmaksız, Hasan Özkan Gezer, Murat Durdu, Aytül Noyan
{"title":"Lichen Sclerosus: A Common but Often Overlooked Condition in Pediatric Patients.","authors":"Begüm Avcı, Gönül Parmaksız, Hasan Özkan Gezer, Murat Durdu, Aytül Noyan","doi":"10.1177/00099228261452276","DOIUrl":"10.1177/00099228261452276","url":null,"abstract":"<p><p>Lichen sclerosus (LS) is a chronic inflammatory dermatosis that is frequently underdiagnosed in pediatric patients, especially girls presenting with persistent urinary symptoms. We aimed to characterize the clinical features and treatment outcomes in children with LS who presented with urinary symptoms. This retrospective study evaluated 88 children diagnosed with LS at a pediatric nephrology center, all of whom presented with urinary symptoms. Diagnosis was based on clinical and dermatoscopic findings. The mean age at diagnosis was 6.0 years, with a median delay of 8 months. Dysuria (79.5%) and pyuria (87.5%) were the most common symptoms, although only 45.5% had confirmed urinary tract infections. Among 60 patients followed (mean duration = 16.8 months), topical pimecrolimus resolved symptoms in 88.3% and improved skin lesions in 66.6%. Lichen sclerosus should be included in the differential diagnosis for children with urinary symptoms. Clinical awareness and early diagnosis can lead to avoiding unnecessary investigations.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1216-1221"},"PeriodicalIF":0.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148316191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2026-10-01Epub Date: 2026-06-06DOI: 10.1177/00099228261457788
{"title":"Corrigendum to \"Investigation of Walking Ability in 161 Patients With Duchenne Muscular Dystrophy\".","authors":"","doi":"10.1177/00099228261457788","DOIUrl":"10.1177/00099228261457788","url":null,"abstract":"","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1206"},"PeriodicalIF":0.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148175396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2026-10-01Epub Date: 2026-06-30DOI: 10.1177/00099228261459939
Peter Newman, Kushal Patel, Judith Rowen, Geetha Radhakrishnan, Donna Mendez
{"title":"The Rash That Will Not Go Away.","authors":"Peter Newman, Kushal Patel, Judith Rowen, Geetha Radhakrishnan, Donna Mendez","doi":"10.1177/00099228261459939","DOIUrl":"10.1177/00099228261459939","url":null,"abstract":"","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1200-1205"},"PeriodicalIF":0.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13499907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148351131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}