Clinical PediatricsPub Date : 2025-07-01Epub Date: 2025-01-08DOI: 10.1177/00099228241309729
Ozan Unlu, Sinem Gulcan Kersin, Tulay Cevlik, Nazmiye Unlu, Hulya Selva Bilgen, Eren Ozek, Onder Sirikci, Goncagul Haklar
{"title":"The Diagnostic Value of Neutrophil and Monocyte Cell Population Data Obtained From a Hematology Analyzer in Neonatal Sepsis.","authors":"Ozan Unlu, Sinem Gulcan Kersin, Tulay Cevlik, Nazmiye Unlu, Hulya Selva Bilgen, Eren Ozek, Onder Sirikci, Goncagul Haklar","doi":"10.1177/00099228241309729","DOIUrl":"10.1177/00099228241309729","url":null,"abstract":"<p><p>We aimed to investigate the diagnostic value of leukocyte cell population data (CPD) parameters obtained from an automated hematology analyzer to be able to use it in the diagnosis of neonatal sepsis. Our study was a retrospective and cross-sectional analysis. The neonates were classified into 3 groups: culture-positive sepsis (n = 20), clinical sepsis (n = 87), and control (n = 269). CPD parameters were determined during complete blood count (CBC) by volume-conductivity-scatter (VCS) technology with DxH 900 Coulter Cell Analyzer. Mean neutrophil volume (MNVNE), standard deviations of volumes of neutrophils (SDVNE), standard deviations of volumes of monocytes (SDVMO), and monocyte distribution width (MDW) were significantly increased in the culture-positive sepsis group compared with the clinical sepsis and control groups (<i>P</i> < .05). We have demonstrated the diagnostic utility of leukocyte CPD parameters, especially MNVNE, MDW, and their combination, for neonatal sepsis. These parameters are advantageous because they are obtained during routine CBC analysis without the need for additional blood collection and extra costs.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"987-995"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-07-01Epub Date: 2025-01-09DOI: 10.1177/00099228241310933
Tingting Zhang, Jingjing Zhou, Yu Xia
{"title":"Exploring Compassion Fatigue in Pediatric Nursing: A Cross-Sectional Study.","authors":"Tingting Zhang, Jingjing Zhou, Yu Xia","doi":"10.1177/00099228241310933","DOIUrl":"10.1177/00099228241310933","url":null,"abstract":"<p><strong>Background: </strong>Compassion fatigue is a state of emotional and physical exhaustion that arises from frequent contact with people who have experienced trauma or stress, which may affect particularly those working in health care. This study aimed to elucidate the prevalence and determinants of compassion fatigue among pediatric nurses.</p><p><strong>Methods: </strong>A survey was administered to pediatric nurses at a tertiary hospital in Jiangsu province, China. Chinese compassion fatigue scale was used to investigate the compassion fatigue.</p><p><strong>Results: </strong>The study enrolled 364 pediatric nurses, with a compassion fatigue prevalence of 59.89%. Age (odds ratio [OR] = 2.094, 95% confidence interval [CI] = 1.833-2.418), education level (OR = 2.118, 95% CI = 1.852-2.669), monthly income (OR = 3.976, 95% CI = 2.904-4.412), and having children at home (OR = 2.314, 95% CI = 1.851-3.025) were independent predictors of compassion fatigue.</p><p><strong>Conclusions: </strong>These findings demonstrate the need for targeted interventions to mitigate compassion fatigue in pediatric nurses.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"1007-1015"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142945787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-07-01Epub Date: 2024-12-24DOI: 10.1177/00099228241307426
Puneet Jairath, Michael Howard Goodstein, Karli Unick, Ryan Sentz
{"title":"Reduction in Antibiotic Usage and Financial Savings Through a Large System Intervention Project.","authors":"Puneet Jairath, Michael Howard Goodstein, Karli Unick, Ryan Sentz","doi":"10.1177/00099228241307426","DOIUrl":"10.1177/00099228241307426","url":null,"abstract":"<p><p>Clinicians continue to seek out ways to decrease antibiotic usage and its sequelae for infants with risk factors for Early Onset Sepsis (EOS). We carried out a large system intervention (LSI) to decrease antibiotic usage, decrease the proportion of infants exposed to any antibiotics and evaluate the financial impact of this intervention. Antibiotic use was monitored from January 2018 through June 2020 for infants born at York Hospital ≥ 35 weeks gestation and discharged from Newborn Nursery. LSIs, including the Kaiser Sepsis Calculator, were implemented January-June 2019. Quality metrics were compared 12-months before and after the intervention. Overall, 5021 infants were discharged from the nursery. Antibiotic usage decreased 68% and infant exposure to antibiotics decreased 64%. There was a savings of $697 per at risk newborn and there were no readmissions for EOS. A Systemic LSI can safely reduce newborn antibiotic exposure and create significant cost saving.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"955-961"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-07-01Epub Date: 2024-12-20DOI: 10.1177/00099228241305853
Maja Vugrinec Mamić, Milan Milošević, Vesna Herceg-Čavrak, Jakov Mamić, Višnja Tokić Pivac
{"title":"Regular Dynamic Exercise Has a Beneficial Effect on Arterial Stiffness Already in Childhood and Adolescence.","authors":"Maja Vugrinec Mamić, Milan Milošević, Vesna Herceg-Čavrak, Jakov Mamić, Višnja Tokić Pivac","doi":"10.1177/00099228241305853","DOIUrl":"10.1177/00099228241305853","url":null,"abstract":"<p><p>This study aims to assess the parameters of arterial stiffness in active children and adolescents according to the type of sport they practice and compare them with those who do not participate in sport. There were 238 subjects, 80 practiced predominantly dynamic sports, 58 predominantly static sports, and 100 children and adolescents were not regularly included in sports. The control group was volunteers of similar age recruited from elementary schools. The control group had statistically significantly higher values of aortic pulse wave velocity (PWVao) in rest compared with the group of children and adolescent athletes (<i>P</i> < .001, median PWVao 6.28 [5.70-7.00] vs 5.74 [5.10-6.23] m/s). This group had a significantly higher body mass index than children and adolescent athletes (<i>P</i> = .046). Children and adolescents who practiced sports with a high level of dynamic load after 2 years showed significantly lower values of PWVao compared with those who practiced sports with a high level of static load (<i>P</i> = .040, PWVao median 5.64 (5.10-6.10) vs 5,95 (5.50-6.50) m/s). Based on our findings, continuous and regular physical activity, especially dynamic, benefits arterial stiffness and arterial blood pressure, the major predictors of cardiovascular risk.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"944-954"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-07-01Epub Date: 2024-12-20DOI: 10.1177/00099228241304480
Brittany A Truitt, Radhika N Ghosh, Eric W Price, Chenxi Du, Shasha Bai, Devon Greene, Dawn M Simon, Walter Reeder, Ajay S Kasi
{"title":"Family Caregiver Knowledge in the Outpatient Management of Pediatric Tracheostomy-Related Emergencies.","authors":"Brittany A Truitt, Radhika N Ghosh, Eric W Price, Chenxi Du, Shasha Bai, Devon Greene, Dawn M Simon, Walter Reeder, Ajay S Kasi","doi":"10.1177/00099228241304480","DOIUrl":"10.1177/00099228241304480","url":null,"abstract":"<p><p>Tracheostomy-related emergencies (TREs) contribute significantly to preventable mortality. The retention of caregiver knowledge and skills acquired through simulation-based training (SBT) is unknown. This study aimed to assess the management of TREs by caregivers who did and did not receive SBT. A questionnaire containing 3 TRE scenarios and frequency of outpatient TREs was administered to 52 caregivers of children with tracheostomies; 34 caregivers had completed SBT. Most caregivers (80%) reported ≥1 TRE since discharge. Only 46% of caregivers answered all 3 TRE questions correctly. No differences were observed in correct responses for accidental decannulation (<i>p</i> = .16), oxygen desaturation (<i>p</i> = .84), and mucus plugging (<i>p</i> = .16) based on the completion of SBT. There were no differences between duration since SBT completion and correct responses for all 3 TRE questions. Caregivers showed knowledge deficiencies in TRE management regardless of SBT completion or duration since SBT. Periodic reassessment of knowledge may create targeted re-education opportunities for TRE management.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"936-943"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-07-01Epub Date: 2024-12-22DOI: 10.1177/00099228241306247
Lora Batson, Pamela K Donohue, Mona-Esmat Jarrah, Brandon M Smith, Caitlin Nalda, Rebecca R Seltzer
{"title":"The Home-Built Environment of Children With Medical Complexity.","authors":"Lora Batson, Pamela K Donohue, Mona-Esmat Jarrah, Brandon M Smith, Caitlin Nalda, Rebecca R Seltzer","doi":"10.1177/00099228241306247","DOIUrl":"10.1177/00099228241306247","url":null,"abstract":"<p><p>This study aimed to describe the home-built environment of children with medical complexity (CMC) using novel photovoice methodology. Parents/guardians of CMC uploaded and discussed photographs of their home environment through semi-structured interviews. Conventional content analysis was applied to interview transcripts embedded with corresponding photographs. All participants modified their home environment to optimize the health, function, and well-being of the child and family; extent of modifications varied. Two main themes and subthemes characterized the home-built environment: (1) replicating hospital function and structure: ensuring accessibility, promoting safety, optimizing organization of supplies, and equipment and (2) maintaining a sense of home: self-expression, entertaining, family participation, and comfort. Elements of hospital structure and function and traditional home aesthetics and utility were equally important to families, the interplay between both facets informed modifications. By understanding the home-built environment, pediatric providers can more holistically support the health and well-being of CMC and their caregivers.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"924-935"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-07-01Epub Date: 2024-12-11DOI: 10.1177/00099228241303595
Hanife Ayşegül Arsoy, Günel Aghazada, Zeliha Demirtaş, Alihan Sürsal, Maide Nur Paksoy Korkudur, Fatih Ozdener
{"title":"Evaluation of the Impact of Enteral Nutrition Support on Anthropometric Measurements and Micronutrient Levels in Malnourished Children.","authors":"Hanife Ayşegül Arsoy, Günel Aghazada, Zeliha Demirtaş, Alihan Sürsal, Maide Nur Paksoy Korkudur, Fatih Ozdener","doi":"10.1177/00099228241303595","DOIUrl":"10.1177/00099228241303595","url":null,"abstract":"<p><strong>Background: </strong>Malnutrition is a critical clinical condition that requires early intervention due to its potential for causing preventable fatalities and complications. This study aims to assess the impact of outpatient enteral nutrition support (ENS) as a therapeutic intervention on anthropometric measurements, intolerance, and micronutrient values in malnourished children.</p><p><strong>Methods: </strong>This observational study included 344 patients in ages 1 to 18 treated with standard enteral nutrition (1.5 kcal/mL energy with fiber). Patient data recorded at admission, in 3 and 6 months, including weight, height, body mass index (BMI), intolerance symptoms, and micronutrient levels. Data were also compared by age groups (1-2, 3-5, 6-12, and 13-18 years of age).</p><p><strong>Results: </strong>Malnutrition was prevalent in the 1- to 5-year age group (63.6%). Age-based analysis showed significant height and BMI z-score improvement in all age groups (<i>P</i> = .009 and <i>P</i> < .001, for all age groups, respectively), except the 13- to 18-year age group (<i>P</i> = .102 and <i>P</i> = .091, respectively). Micronutrient values remained within healthy ranges with minimal fluctuations. The ENS was well tolerated by 62.5% of patients, and the most common intolerance symptoms were constipation (15.4%), vomiting (8.1%), and nausea (7.3%).</p><p><strong>Conclusion: </strong>This study demonstrates that outpatient ENS therapy for 6 months significantly improved anthropometric measurements in malnourished children and was well tolerated. The 1 to 2 age group exhibited the most substantial response to treatment, whereas the 1 to 5 age group required at least 6 months of nutritional therapy to prevent stunting. However, the effect of ENS therapy on height and BMI z-scores in the 13 to 18 age group appeared insufficient after 3 months.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"913-923"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-07-01Epub Date: 2024-12-31DOI: 10.1177/00099228241307441
Roya Tahlili, Alireza Mardanshahi, Seyed Mohammad Abedi, Hamid Mohammadjafari
{"title":"The Role of Quantitative DMSA Scan Analysis in Assessing Prognosis of Acute Pyelonephritis in Children.","authors":"Roya Tahlili, Alireza Mardanshahi, Seyed Mohammad Abedi, Hamid Mohammadjafari","doi":"10.1177/00099228241307441","DOIUrl":"https://doi.org/10.1177/00099228241307441","url":null,"abstract":"<p><strong>Objective: </strong>We assessed the quantitative pattern of Dimercaptosuccinic acid scan (DMSA) in children with acute pyelonephritis.</p><p><strong>Methods: </strong>In a retrospective study, we reviewed DMSA of children with APN based on 7 qualitative and quantitative items.</p><p><strong>Results: </strong>A total of 186 patients (age 27.8 ± 25.9 months, 157 (84%) female) enrolled in the study. The global defect was not found in 90% of children as well differential function ≥40% in 86% of patients. The other 5 items showed abnormal findings in 57% to 67% of children. Abnormality in the extent of defect, total points of involvement, number of involved segments, and differential renal function significantly predict late DMSA disturbances. There was no significant difference between patients with different grades of vesicoureteral reflux in any items on DMSA. We found no significant relationship between any items on DMSA and recurrent urinary tract infection (UTI).</p><p><strong>Conclusion: </strong>Quantitative assessment of DMSA offers at least 4 items that reveal subtle cortical involvements with long-term significance.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":"64 7","pages":"979-986"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-07-01Epub Date: 2024-12-22DOI: 10.1177/00099228241308006
Fadime Üstüner Top, Barış Kaya
{"title":"The Relationship between Parents' Use of the Pediatric Emergency Department and Cyberchondria.","authors":"Fadime Üstüner Top, Barış Kaya","doi":"10.1177/00099228241308006","DOIUrl":"10.1177/00099228241308006","url":null,"abstract":"<p><p>The study aimed to investigate the correlation between children's attendance at the emergency department and the cyberchondria of parents. The population for this cross-sectional study comprised parents of children aged 0 to 18 attending the emergency department. Research data were collected using an Information Form, the Cyberchondria Severity Scale (CSS). The participants had mean CSS scores of 41.45 ± 19.22. There were significant differences observed between the reason for choosing the emergency department with mean scores for the total CSS (<i>F</i> = 2.289, <i>P</i> = .021), distress (<i>F</i> = 2.466, <i>P</i> = .013), and compulsion (<i>F</i> = 2.822, <i>P</i> = .005) subscales. A weak positive correlation was identified between the number of attendances at the emergency department in the last year and the excessiveness (<i>r</i> = .204) subscale. Participants had moderate levels of CSS. According to the research findings, most parents attended the emergency department for non-urgent reasons. In addition, as the cyberchondria severity level of parents increased, their attendance at health institutions and emergency departments was determined to increase.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"996-1006"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}