Clinical PediatricsPub Date : 2025-06-01Epub Date: 2024-11-21DOI: 10.1177/00099228241296235
Agustín Cámara-Domínguez, Alexandra Margaret Stuart-Aguiar, Nicte-Há Asunción Fuentes-Canto, Andrea Cervera-Rosado, Cuauhtli Nacxitl Azotla-Vilchis, Luz Del Carmen Márquez-Quiroz, Rodrigo Vargas-Méndez, Silvina Noemí Contreras-Capetillo
{"title":"15q24 Duplication: A Case Report of Neurodevelopmental Delay.","authors":"Agustín Cámara-Domínguez, Alexandra Margaret Stuart-Aguiar, Nicte-Há Asunción Fuentes-Canto, Andrea Cervera-Rosado, Cuauhtli Nacxitl Azotla-Vilchis, Luz Del Carmen Márquez-Quiroz, Rodrigo Vargas-Méndez, Silvina Noemí Contreras-Capetillo","doi":"10.1177/00099228241296235","DOIUrl":"10.1177/00099228241296235","url":null,"abstract":"<p><p>Chromosomal rearrangements are structural anomalies that affect chromosomal architecture and can impact gene expression, genomic imprinting, or even generate de novo gene fusions, as seen in hematological chromosomal aberrations. Chromosomal rearrangements can be associated with syndromes causing neurodevelopmental delay, autism spectrum disorder, and variable dysmorphic features. This article presents the clinical and molecular characteristics of a 2-year-old male child with neurodevelopmental delay who was diagnosed with a chromosomal rearrangement due to a 15q24 duplication (dup15q24). The 15q24 locus presents controversy between the phenotype associated with duplication and deletion, thus posing a challenge in differential diagnosis for both. The phenotypes of autism spectrum disorder and pediatric patients with language delay should be evaluated by a multidisciplinary team comprising genetics, pediatrics, and pediatric neurology to shorten the diagnostic odyssey for patients with rare diseases and to impact the quality of life of the patient and their family.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"764-770"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142686165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-06-01Epub Date: 2024-11-30DOI: 10.1177/00099228241301848
Meredith R Denney, Kelly Moore, Barron Patterson, Adriana Bialostozky, Elizabeth Williams
{"title":"<i>Mobile Flu Fighter!</i> Development and Pilot Implementation of a Mobile Vaccination Program to Reduce Pediatric Influenza Vaccination Disparities.","authors":"Meredith R Denney, Kelly Moore, Barron Patterson, Adriana Bialostozky, Elizabeth Williams","doi":"10.1177/00099228241301848","DOIUrl":"10.1177/00099228241301848","url":null,"abstract":"<p><p>Severe pediatric influenza outcomes disproportionately affect racial minority groups, yet flu vaccination rates are often lower in these populations. Community Engagement Studios were conducted among parents/caregivers who refused flu vaccination for their children to discuss vaccination decision-making. A pilot program, <i>Mobile Flu Fighter!</i>, was created for pediatric patients in Nashville, Tennessee, and 4 events were conducted during the 2021 to 2022 flu season. Events provided free flu vaccines to all eligible children (aged 6 months to <u><</u>18 years old), recorded vaccinations in electronic medical records and the state vaccine registry, and incorporated community partners. Events resulted in 49 pediatric flu vaccinations. Patient flu vaccination rates were compared with previous seasons, which resulted in an overall decrease in 2.9% to 3.5%. The decrease may be influenced by factors like COVID-19 vaccine hesitancy, vaccine infodemics, and not employing family-centered approaches. More work is necessary to reduce pediatric vaccination disparities.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"830-840"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-06-01Epub Date: 2024-11-17DOI: 10.1177/00099228241293047
Joseph Peeden, Anna Conner, Dante Pappano
{"title":"Streptococcal Mediastinitis Following Placement of a Bravo<sup>™</sup> Capsule.","authors":"Joseph Peeden, Anna Conner, Dante Pappano","doi":"10.1177/00099228241293047","DOIUrl":"10.1177/00099228241293047","url":null,"abstract":"","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"613-615"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-06-01Epub Date: 2024-12-20DOI: 10.1177/00099228241303600
Elber Yuksel Aydin, Matthew Garber, C Krystyn Stocking, Charlene Pringle, Jose Irazuzta
{"title":"Bronchiolitis: Impact of Age and Etiology on Morbidity and Mortality in Previously Healthy Critically Ill Children.","authors":"Elber Yuksel Aydin, Matthew Garber, C Krystyn Stocking, Charlene Pringle, Jose Irazuzta","doi":"10.1177/00099228241303600","DOIUrl":"10.1177/00099228241303600","url":null,"abstract":"<p><p>This retrospective, multicenter observational study analyzed data from 257 children under 2 years old admitted with viral bronchiolitis to pediatric intensive care units (PICU) at Wolfson Children's Hospital and UFHealth Shands Children's Hospital from January 2020 to March 2022. The study explores viral etiologies and their associations with hospital length of stay (H-LOS), PICU length of stay (P-LOS), and severity markers and scores. Younger age was associated with longer H-LOS and P-LOS (<i>P</i> < .001). Respiratory syncytial virus (RSV) was associated with younger age but not with H-LOS when controlled for age. RSV's impact on H-LOS varied by age (<i>P</i> = .018). Markers of severity did not differ between patients infected with RSV versus those without RSV, or in patients with co-infection versus single infection. In our population, pSOFA performed better than PELOD-2 in disease severity assessment.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"887-893"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-06-01Epub Date: 2024-09-27DOI: 10.1177/00099228241283276
Halil Dogrul, Yusuf Cetin Doganer, Umit Aydogan, Rumeysa Nur Bayrak
{"title":"Association Between Sleep Hygiene Parameters and Sleep Habits in 5- to 10-Year-Old School-Age Children.","authors":"Halil Dogrul, Yusuf Cetin Doganer, Umit Aydogan, Rumeysa Nur Bayrak","doi":"10.1177/00099228241283276","DOIUrl":"10.1177/00099228241283276","url":null,"abstract":"<p><p>Insufficient sleep can lead to problems. We examined the sociodemographic characteristics, sleep habits, and association between sleep problems. Parents were requested to fill out a survey and Children's Sleep Habits Questionnaire (CSHQ). The mean age of 1226 students was 8.42 (5.0-10.0) years. A total of 50.7% were male students. In addition, 69.1% showed signs of sleep problems in the CSHQ. In multivariate logistic regression analysis, bed-sharing, owning cell phone, attending early education group, not using toilet before bedtime, television watching duration, being an only child, not doing physical activity, watching TV before bed on weekends, caffeinated beverage consumption, not reading a book before sleep, waking up at night, sleeping in lighted rooms, maternal education level, having 1 sibling, and not having tablet variables were statistically significant in causing sleep problems. Poor sleep habits and sleep hygiene problems are common in school-age children. Healthy sleep habits are essential to get adequate and quality sleep.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"616-630"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-06-01Epub Date: 2024-11-28DOI: 10.1177/00099228241299897
Ellen A Lipstein, Isabella K Pallotto, Chelsey B Anderson, Mary Anne Ammon, Adam C Carle
{"title":"Health Care Provider Perspectives on Shared Decision Making With Parents and Adolescents.","authors":"Ellen A Lipstein, Isabella K Pallotto, Chelsey B Anderson, Mary Anne Ammon, Adam C Carle","doi":"10.1177/00099228241299897","DOIUrl":"10.1177/00099228241299897","url":null,"abstract":"<p><p>Little is known about health care provider perspectives on sharing decisions in a parent-adolescent-provider triad. This perspective is needed to develop tools for supporting shared decision-making (SDM) in a triad that involves an adolescent. To assess this perspective, we conducted individual interviews with pediatric health care providers. Trained study staff interviewed health care providers who work with adolescents with chronic conditions about their medical decision-making experience and key components of SDM. Interviews were transcribed, coded, and analyzed using thematic content analysis. Our analysis elicited 3 major themes: (1) roles of each triad member; (2) key aspects of triadic SDM components; and (3) essentials for triadic SDM with an adolescent. Providers discussed the importance of alignment between parents and adolescents and facilitating such alignment through preference discussions. We found that providers want to engage adolescents with chronic conditions and their parents and achieve alignment between these 2 parties, during shared medical decisions.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"809-815"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142738666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-06-01Epub Date: 2024-12-20DOI: 10.1177/00099228241304469
Muhammed Fatih Satılmaz, Mehmet Gökhan Aslan, Mert Beşenek
{"title":"Evaluation of Ocular Parameters in Newly Diagnosed Obsessive-Compulsive Disorder Children With Eye-Rubbing Compulsion.","authors":"Muhammed Fatih Satılmaz, Mehmet Gökhan Aslan, Mert Beşenek","doi":"10.1177/00099228241304469","DOIUrl":"10.1177/00099228241304469","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the ocular structural changes in obsessive-compulsive disorder (OCD) children with eye-rubbing compulsion.</p><p><strong>Methods: </strong>Participants recruited at the child and adolescent psychiatry clinic were evaluated for the OCD diagnosis. All patients underwent imaging with Scheimpflug corneal topography (Sirius, CSO, Italy), Tomey EM-4000 specular microscopy (Nagoya, Japan), and Lenstar LS 900 (Haag-Streit AG, Switzerland) optical biometry.</p><p><strong>Results: </strong>Both naive OCD and healthy control groups consisted of 40 patients. Mean cylindric diopter, coma, and trefoil values were significantly higher in the right eyes of OCD children. (<i>P</i> = .043, .024, and .028, respectively). Besides, lens thickness, total ocular aberrations, and high ocular aberrations (<i>P</i> = .014, .040; .027, .038; and.020, .013, in right and left eyes, respectively) were bilaterally higher in OCD children.</p><p><strong>Conclusion: </strong>Eye rubbing and mechanical trauma were proposed as risk factors for ocular structural changes. Early evaluation of corneal topographic parameters such as CylD, coma, and trefoil aberrations in newly diagnosed OCD children might assist in preventing future corneal ectatic diseases.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"877-886"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-06-01Epub Date: 2024-10-10DOI: 10.1177/00099228241284345
Ian Bogdanowicz, Kyle Plante, John Leddy, Christina Master, Mohammad Haider
{"title":"Quality of Life in Adolescent Athletes With Sport-Related Concussion Prescribed Heart Rate-Targeted Aerobic Exercise Within 10 Days of Injury.","authors":"Ian Bogdanowicz, Kyle Plante, John Leddy, Christina Master, Mohammad Haider","doi":"10.1177/00099228241284345","DOIUrl":"10.1177/00099228241284345","url":null,"abstract":"<p><p>Individualized aerobic exercise treatment prescribed within 10 days of injury facilitates recovery in adolescents after sport-related concussion (SRC) and reduces incidence of persisting post-concussive symptoms (PPCSs) beyond 4 weeks. The effect of aerobic exercise treatment on quality of life symptoms is, however, unknown. This planned secondary aim of a published randomized controlled trial found that while adolescents prescribed aerobic exercise recovered faster, there was no difference on the Pediatric Quality of Life (PedsQL) questionnaire scores during the 4-week intervention period. Nevertheless, adolescents who experienced PPCS reported significantly worse initial visit (within 10 days of injury) symptoms on the PedsQL than those who recovered within 4 weeks. Higher scores on the PedsQL correlated with greater initial visit concussion symptom burden and more abnormalities on a concussion-relevant visio-vestibular examination. Thus, the PedsQL captures the clinical severity of concussion and is prognostic of risk for delayed recovery when administered early after SRC in adolescents.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"631-641"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142388541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical PediatricsPub Date : 2025-06-01Epub Date: 2024-12-27DOI: 10.1177/00099228241304464
Loretta Cinquepalmi, Adetunbi Ayeni, Laura Melville, Christopher Kelly
{"title":"Parental Perceptions and Practices Regarding Pain Management and Medical Marijuana Use in Patients With Sickle Cell Disease.","authors":"Loretta Cinquepalmi, Adetunbi Ayeni, Laura Melville, Christopher Kelly","doi":"10.1177/00099228241304464","DOIUrl":"10.1177/00099228241304464","url":null,"abstract":"<p><p>Parental strategies for home management of pain crisis in children with sickle cell anemia are not well studied. Non-steroidal anti-inflammatory medications (NSAIDs) are thought of as the mainstay of home and in-patient pain management for pediatric patients with sickle cell disease. Parents and providers often fear the use of opioids due to the risk of addiction. Medical marijuana is a potential adjunct therapy, but parental concerns regarding its use are not known. We aimed to assess parental strategies for home pain control, as well as attitudes toward the use of medical marijuana in children with sickle cell disease. Although medical marijuana may be a safer alternative to opioids, parents had similar concerns regarding marijuana. There were significant concerns regarding the societal implications of marijuana use. Further study of the utility of marijuana is warranted, but clinicians must look beyond the medical and consider the social consequences that may impact treatment acceptability.</p>","PeriodicalId":10363,"journal":{"name":"Clinical Pediatrics","volume":" ","pages":"824-829"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142892671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}