Climacteric最新文献

{"title":"Menopause in low and middle-income countries: a scoping review of knowledge, symptoms and management.","authors":"Rakibul M Islam, Juwel Rana, Sadia Katha, Md Anwer Hossain, Siraj Us Salekin, Anika Tasneem Chowdhury, Ashraful Kabir, Lorena Romero, Susan R Davis","doi":"10.1080/13697137.2025.2509254","DOIUrl":"10.1080/13697137.2025.2509254","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to systematically map available evidence on menopause-related knowledge, symptoms and management in low and middle-income countries (LMICs) and identify critical gaps to inform research and policy.</p><p><strong>Methods: </strong>Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Review (PRISMA-ScR) guidelines, the MEDLINE, EMBASE, CINAHL and Scopus databases were searched for studies published between 2000 and 2024. Eligible studies were those that reported on menopause-related knowledge, symptom prevalence or management in LMICs. Data were extracted and synthesised descriptively and thematically.</p><p><strong>Results: </strong>From 10,758 records, 252 studies from 41 LMICs were included. Most were cross-sectional (85%) and relied on non-probability sampling (62%), with only 4% being nationally representative. Menopause classification methods were often inconsistent, with only 17.5% of studies using the Stages of Reproductive Aging Workshop (STRAW) +10 or World Health Organization (WHO) criteria. National-level data on age at menopause are lacking across all LMICs. The prevalences of vasomotor symptoms, joint pain and sexual concerns were comparable with high-income countries. However, data on the severity and burden of symptoms were scarce. Knowledge about menopause and menopausal hormone therapy (MHT) was poor, especially in low-income and rural settings. Cultural stigma, misconceptions and healthcare provider knowledge gaps contributed to low uptake of evidence-based menopause care. MHT use was consistently low, with women predominantly using traditional remedies. Provider hesitancy, lack of training and structural health system barriers were key limitations in service delivery.</p><p><strong>Conclusions: </strong>Despite a growing population of postmenopausal women, menopause remains a neglected health issue across LMICs. There is an urgent need to integrate menopause into reproductive and non-communicable disease policies, invest in provider education and ensure equitable access to evidence-based menopause care, including MHT, for women in LMICs.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"242-279"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Premature ovarian insufficiency and the risk of breast cancer: author reply.","authors":"Nick Panay, Nathalie Vermeulen, Richard A Anderson, Amanda J Vincent","doi":"10.1080/13697137.2025.2480588","DOIUrl":"10.1080/13697137.2025.2480588","url":null,"abstract":"","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"367-368"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction.","authors":"","doi":"10.1080/13697137.2025.2485571","DOIUrl":"10.1080/13697137.2025.2485571","url":null,"abstract":"","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"369"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menopause in low and middle-income countries - an untold story.","authors":"Nicole G Jaff, Nigel J Crowther","doi":"10.1080/13697137.2025.2513140","DOIUrl":"https://doi.org/10.1080/13697137.2025.2513140","url":null,"abstract":"","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":"28 3","pages":"217-219"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menopausal symptoms and risk factors in Chinese women: a multicenter cross-sectional study.","authors":"Ruiyi Tang, Qingyuan Liu, Jie Li, Mei Li, Hongxia Wang, Qi Yu","doi":"10.1080/13697137.2025.2500563","DOIUrl":"10.1080/13697137.2025.2500563","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to examine menopausal symptoms and their associated factors among premenopausal, perimenopausal and postmenopausal groups of middle-aged Chinese women.</p><p><strong>Methods: </strong>The nationwide cross-sectional study involved 9740 middle-aged women from 115 medical centers across 27 provinces in China. Logistic regression analyses were performed to explore the associations between menopausal symptom severity and age, menopausal status, body mass index (BMI), smoking, employment status, income, education level, exercise and alcohol use.</p><p><strong>Results: </strong>Among the 9740 participants, 17.6% (<i>n</i> = 1711) were premenopausal, 38.3% (<i>n</i> = 3730) were perimenopausal and 44.1% (<i>n</i> = 4299) were postmenopausal. The likelihood of moderate to severe menopausal symptoms was positively associated with age (odds ratio [OR] 1.10; 95% confidence interval [CI] 1.09-1.11; <i>p</i> < 0.001), perimenopause (OR 2.15; 95% CI 1.90-2.45; <i>p</i> < 0.001) and postmenopausal stage (OR 5.96; 95% CI 5.25-6.77; <i>p</i> < 0.001), smoking (OR 1.96; 95% CI 1.39-2.77; <i>p</i> < 0.001) and unemployment (OR 1.47; 95% CI 1.31-1.65; <i>p</i> < 0.001). In contrast, higher income was inversely associated with symptom severity (OR 0.69; 95% CI 0.58-0.82; <i>p</i> < 0.001). BMI demonstrated a positive association with symptom severity in premenopausal women.</p><p><strong>Conclusions: </strong>Age, menopausal status, smoking, unemployment and lower income were associated with more severe menopausal symptoms.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"312-318"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations in the prevalence of premature and early menopause in low and middle-income regions: a cross-sectional study.","authors":"Sydney Ross, Sol P Juárez","doi":"10.1080/13697137.2025.2500561","DOIUrl":"10.1080/13697137.2025.2500561","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to examine differences in premature and early menopause across various regions in low and middle-income countries (LMICs).</p><p><strong>Methods: </strong>Data for 55 LMICs from the Demographic and Health Surveys (2013-2023) were classified into nine regions. Proportions of premature (aged <40 years) and early (aged <45 years) menopause were calculated. Logistic regressions adjusted for covariates were also run.</p><p><strong>Results: </strong>The proportion of women in premature menopause ranged from 1.58% in the European and Eastern Mediterranean regions to 6.87% in Southern Africa. For early menopause, proportions ranged from 4.92% in the Eastern Mediterranean region to 15.21% in the Americas. The Eastern Mediterranean region had systematic lower odds across menopause categories, even after the adjustments for relevant covariates.</p><p><strong>Conclusion: </strong>Significant variation exists in the proportion of the different age at menopause categories within LMIC regions. Higher proportions of premature and early menopause were found in all LMIC regions compared to those reported in current literature from high-income countries. A global health perspective on menopause is urgently needed, especially in relation to the increased disease risks with early and premature menopause, such as cardiovascular disease.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"360-364"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"REDLINC: two decades of collaborative insights into menopause and women's health in Latin America.","authors":"Konstantinos Tserotas, Juan Enrique Blumel","doi":"10.1080/13697137.2025.2501255","DOIUrl":"10.1080/13697137.2025.2501255","url":null,"abstract":"<p><p>The Collaborative Group for Research of the Climacteric in Latin America (REDLINC) was established 20 years ago and comprises physicians who specialize in menopause medicine to acquire local information and understand the health needs of our population. Since then, 12 collaborative multinational studies have been conducted. Some of our most relevant results are the average age of menopause in Latin America (48.6 years), and the significant impact on quality of life, metabolic syndrome, sleep issues, sexual dysfunction, anxiety, depression, muscle pain, low muscle mass and mild cognitive decline. Also, we report variations in menopausal hormone therapy (MHT) prescriptions, noting that the tendency to prescribe is stronger among physicians themselves than toward patients. Finally, several factors contribute to the prevention, alleviation and treatment of menopausal changes in women, such as obesity control, exercise, higher education, utilization of MHT and seeking help from menopause practitioners. This article highlights the gathered information on Latin American women, which has been implemented for patients' better understanding. Physicians' awareness has grown, protocols have been adapted to accommodate our healthcare realities and patients are seeking menopause healthcare practitioners. International collaboration is key to the success of this project.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"220-229"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menopausal symptoms among perimenopausal women in rural Turkey: a cross-sectional study.","authors":"Ipek Betul Ozcivit Erkan, Atilim Gulcicek, Ugurcan Sayili, Vasfiye Bayram Deger, C Tamer Erel, Levent M Senturk","doi":"10.1080/13697137.2025.2490243","DOIUrl":"10.1080/13697137.2025.2490243","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the prevalence and severity of menopausal symptoms among perimenopausal women in a rural area of southeastern Turkey and their association with sleep quality, depression and sociodemographic and lifestyle-related factors.</p><p><strong>Methods: </strong>This cross-sectional study included 122 perimenopausal women aged 40-55 years residing in southeastern rural Turkey. Participants completed the Beck Depression Inventory (BDI), the Menopause Rating Scale (MRS) and the Pittsburgh Sleep Quality Index (PSQI), alongside demographic data collection.</p><p><strong>Results: </strong>The median age was 46 years (43-49 years). Higher MRS scores were significantly linked to a sedentary lifestyle, poor self-rated health and concerns about partner infidelity. MRS total scores were moderately correlated with global PSQI scores (<i>r</i> = 0.49, <i>p</i> < 0.001) and strongly correlated with BDI scores (<i>r</i> = 0.71, <i>p</i> < 0.001). Severe menopausal symptoms were significantly associated with poor sleep quality (odds ratio [OR] = 2.62; 95% confidence interval [CI]: 1.16-5.95), mild to severe depression (OR = 4.78; 95% CI: 2.08-10.98) and poor self-rated general health (OR = 2.76; 95% CI: 1.03-7.41), even after adjusting for age, parity and body mass index.</p><p><strong>Conclusions: </strong>Perimenopausal women in southeastern rural Turkey experience severe menopausal symptoms that are significantly associated with self-rated general health, sleep quality and depression.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"304-311"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menopausal symptoms: what are the differences between the West and the East?","authors":"Ruiyi Tang, Qingyuan Liu, Qi Yu","doi":"10.1080/13697137.2025.2503880","DOIUrl":"https://doi.org/10.1080/13697137.2025.2503880","url":null,"abstract":"<p><p>The characteristics of menopause symptoms exhibit considerable variation across different countries and regions. Understanding these variations is crucial for developing strategies to manage the menopausal symptoms specific to each region. A comparative analysis of menopausal symptoms between the East and the West is presented, based on a review of the epidemiological literature and data. In the East, the age of menopause and the onset of the menopausal symptoms were observed to occur slightly earlier than in the West. The two most commonly reported menopausal symptoms in western countries are hot flushes and sleeplessness, whereas Asian women mostly report somatic symptoms. The reported prevalence of menopausal symptoms varies considerably and differs substantially between the studies. These variations may be related to research methods, sample size, ethnicity, culture, socioeconomic differences, menopausal status and other factors.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-6"},"PeriodicalIF":2.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Premature ovarian insufficiency: addressing the most controversial issues.","authors":"Nick Panay","doi":"10.1080/13697137.2025.2497415","DOIUrl":"https://doi.org/10.1080/13697137.2025.2497415","url":null,"abstract":"<p><p>It was a true honor to be invited as President to deliver the Pieter Van Keep oration at the 2024 International Menopause Society (IMS) Congress in Melbourne, Australia. There was never any doubt that the topic of my lecture would be premature ovarian insufficiency (POI). POI is a condition which has been neglected for far too long given its greater global prevalence than originally estimated and its implications to the sufferers, both in terms of quality of life and long-term well-being. The hope is that we are now entering a new era of awareness given the recent update of the European Society of Human Reproduction (ESHRE) POI guideline, achieved through a partnership of the ESHRE, American Society for Reproductive Medicine (ASRM), Centre for Research Excellence in Women's Health in Reproductive Life (CRE WHiRL) at Monash University and IMS with support from numerous global stakeholder organizations. Whilst as a minimum the update of the guideline is expected to improve clinical management of this condition, the process has also identified key areas of much-needed research, where currently only practical guidance can be given due to the lack of data. The aim of my Pieter Van Keep lecture, and therefore this article, was not to replicate the extensive work already conducted to systematically review the literature for the guideline. The aim was to provide a state-of-the-art commentary highlighting the key controversial topics regarding this distressing condition, and how these are being addressed, or should be addressed in the future, for the sake of sufferers and their families.</p>","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-7"},"PeriodicalIF":2.9,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}