Climacteric最新文献_第10页

Artificial intelligence applications in gynecological cancer detection. 人工智能在妇科癌症检测中的应用。

IF 3.2 4区医学

Climacteric Pub Date : 2026-04-01 Epub Date: 2026-03-11 DOI: 10.1080/13697137.2026.2633071

Tevfik Yoldemir

引用次数: 0

Sleep disorders and menopausal symptoms: a Latin American perspective on postmenopausal health. 睡眠障碍和更年期症状：拉丁美洲对绝经后健康的看法。

IF 3.2 4区医学

Climacteric Pub Date : 2026-04-01 Epub Date: 2025-08-13 DOI: 10.1080/13697137.2025.2537979

Eugenio E Arteaga, Juan E Blümel, María S Vallejo, Carlos Salinas, Konstantinos Tserotas, Andrés Calle, Maribel Dextre, Alejandra Elizalde, María T Espinoza, Carlos Escalante, Gustavo Gómez-Tabares, Alejandra Martínez-García, Álvaro Monterrosa-Castro, Mónica Ñañez, Eliana Ojeda, Claudia Rey, Doris Rodríguez-Vidal, Marcio A Rodrígues

{"title":"Sleep disorders and menopausal symptoms: a Latin American perspective on postmenopausal health.","authors":"Eugenio E Arteaga, Juan E Blümel, María S Vallejo, Carlos Salinas, Konstantinos Tserotas, Andrés Calle, Maribel Dextre, Alejandra Elizalde, María T Espinoza, Carlos Escalante, Gustavo Gómez-Tabares, Alejandra Martínez-García, Álvaro Monterrosa-Castro, Mónica Ñañez, Eliana Ojeda, Claudia Rey, Doris Rodríguez-Vidal, Marcio A Rodrígues","doi":"10.1080/13697137.2025.2537979","DOIUrl":"10.1080/13697137.2025.2537979","url":null,"abstract":"Objective: This cross-sectional, observational study, conducted in nine Latin American countries, aimed to examine the association between hot flashes and insomnia, and whether the severity of vasomotor symptoms (VMS) correlates with sleep disturbances.Method: The study collected sociodemographic and clinical data, and evaluated the presence of sleep disorders using Jenkin's Sleep Scale (JSS-4) and menopausal symptoms using the Menopause Rating Scale (MRS) questionnaire.Results: The study included 1185 postmenopausal women with average age 56.9 ± 5.7 years, body mass index (BMI) of 26.5 ± 5.2 kg/m² and 8.6 ± 6.4 years since menopause. Overall, 20.6% reported sleep disturbances. Compared to those without sleep problems, affected women had longer postmenopausal duration (12 ± 9.0 vs. 10.8 ± 7.8, p < 0.03), had higher BMI (27.9 ± 5.6 vs. 26.1 ± 5.0, p < 0.001), were more often smokers and homemakers, and had more comorbidities. They were also less likely to have a partner or have used menopausal hormone therapy. Sleep disturbances increased proportionally with VMS severity (p < 0.01). In multivariate analysis, sleep disorders were associated with VMS (odds ratio [OR] 4.47), psychotropic use (OR 1.84), obesity (OR 1.45) and comorbidities (OR 1.45).Conclusion: Women with VMS were more likely to experience sleep disorders and this effect was proportional to the magnitude of the hot flashes. The study also presents several factors associated with sleep disorders in postmenopausal women that should be considered to help prevent these disturbances.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"256-262"},"PeriodicalIF":3.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144844728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is the patients' fear of cancer the main barrier to prescribing menopausal hormone therapy? 患者对癌症的恐惧是绝经期激素治疗的主要障碍吗？

IF 3.2 4区医学

Climacteric Pub Date : 2026-04-01 Epub Date: 2025-09-26 DOI: 10.1080/13697137.2025.2560327

Isabella Melo Pompei, Sabrina Lara Abonizio Magdalena, Vivien Suemi Arimura, Rogério Bonassi Machado, César Eduardo Fernandes, Rossella Elena Nappi, Luciano Melo Pompei

{"title":"Is the patients' fear of cancer the main barrier to prescribing menopausal hormone therapy?","authors":"Isabella Melo Pompei, Sabrina Lara Abonizio Magdalena, Vivien Suemi Arimura, Rogério Bonassi Machado, César Eduardo Fernandes, Rossella Elena Nappi, Luciano Melo Pompei","doi":"10.1080/13697137.2025.2560327","DOIUrl":"10.1080/13697137.2025.2560327","url":null,"abstract":"Objective: Menopausal hormone therapy (MHT) is the most effective treatment for relieving menopausal symptoms. However, many women avoid this therapy due to fear, and in Brazil numerous cities lack access to this treatment in the public health system. This study aimed to investigate prescribing habits regarding MHT among gynecologist-obstetricians in the Brazilian public versus private health systems, and to identify the main barriers to its use.Method: This descriptive cross-sectional study utilized a quantitative approach. Gynecologist-obstetricians from across Brazil were invited to complete a structured electronic questionnaire assessing their prescribing practices in both the public and private health sectors.Result: A total of 433 valid responses were analyzed. Among them, 51.5% of participants reported providing care to climacteric patients in the public health system, with 46.2% working in both sectors. Among physicians practicing in both settings, 76.5% reported prescribing MHT more frequently in the private sector. The main barriers to MHT prescription in the public system were treatment cost (68.2%) and lack of availability of free medication (61.4%), while in the private system the predominant barriers were fear of therapy-related risks (93.6%), especially cancer. Only 27.8% reported free access to MHT in their cities.Conclusion: The findings indicate that MHT prescribing practices in Brazil are still significantly influenced by structural barriers in the public sector and by negative perceptions in the private sector. Interventions aimed at expanding access and educating both physicians and patients are essential to ensure safe and equitable use of MHT.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"227-230"},"PeriodicalIF":3.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety and performance of photobiomodulation delivered by vaginal probe in patients with genitourinary syndrome of menopause. 绝经期泌尿生殖系统综合征患者阴道探头光生物调节的安全性和效果。

IF 3.2 4区医学

Climacteric Pub Date : 2026-04-01 Epub Date: 2025-12-17 DOI: 10.1080/13697137.2025.2591279

Jennifer Salerno, Chris Serrand, Sarah Kabani, Thierry Chevallier, Renaud de Tayrac, Pierre Marès

{"title":"Safety and performance of photobiomodulation delivered by vaginal probe in patients with genitourinary syndrome of menopause.","authors":"Jennifer Salerno, Chris Serrand, Sarah Kabani, Thierry Chevallier, Renaud de Tayrac, Pierre Marès","doi":"10.1080/13697137.2025.2591279","DOIUrl":"10.1080/13697137.2025.2591279","url":null,"abstract":"Objective: Genitourinary syndrome of menopause (GSM) has a negative impact on quality of life. Treatments for GSM are largely hormonal, yet some patients remain symptomatic after recommended treatments. Photobiomodulation therapy (PBMT) is a promising non-hormonal technique.Method: In this prospective, first-in-human, medical device safety study, postmenopausal patients with pelvic pain due to vaginal atrophy after failure of non-invasive therapies for >3 months were recruited. Exclusion criteria included pelvic pain of physical and/or psychological origin, treatment for cancer or immunosuppression. Patients received six weekly PBMT sessions using the MILTA GYNECO vaginal probe (PHYSIOQUANTA). The primary outcome was device safety, according to patient-reported adverse events. Secondary outcomes were vaginal mucosal health (vaginal health index [VHI]), pain (0-10 visual analog scale), vaginal flora and patient satisfaction (Patient Global Impression of Change [PGI-C]).Results: Twenty-five patients were recruited and analyzed, with an average age of 58.7 years. In total, 148 adverse events were declared, of which 146 were minor (grade I) and most were for heat sensation (89.2%). Significant improvements were found in pain during intercourse (7.65 [±1.95] before versus 3.89 [±2.44] after, p < 0.0001) and in vaginal health according to the VHI score (12.68 [±4.20] before versus 17.63 [±4.35] after, p < 0.0001). According to the PGI-C score, most patients rated their condition as improved.Conclusion: Even when applying a broad definition for adverse events, these preliminary data suggested that PBMT using the MILTA GYNECO vaginal probe was safe, with high patient satisfaction. The next step is to assess the efficacity of the medical device in a randomized trial.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"293-299"},"PeriodicalIF":3.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145767141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction. 修正。

IF 3.2 4区医学

Climacteric Pub Date : 2026-04-01 Epub Date: 2026-03-25 DOI: 10.1080/13697137.2026.2638063

引用次数: 0

Younger midlife females with bilateral salpingo-oophorectomy: respiratory disturbances during sleep. 双侧输卵管卵巢切除术的年轻中年女性：睡眠时呼吸障碍。

IF 3.2 4区医学

Climacteric Pub Date : 2026-04-01 Epub Date: 2025-12-22 DOI: 10.1080/13697137.2025.2595987

Laura Gravelsins, Nicole J Gervais, Alana Brown, Shreeyaa Ramana, Sophia Zhao, Gina Nicoll, Marcus Q Bernardini, Michelle Jacobson, Gillian Einstein

{"title":"Younger midlife females with bilateral salpingo-oophorectomy: respiratory disturbances during sleep.","authors":"Laura Gravelsins, Nicole J Gervais, Alana Brown, Shreeyaa Ramana, Sophia Zhao, Gina Nicoll, Marcus Q Bernardini, Michelle Jacobson, Gillian Einstein","doi":"10.1080/13697137.2025.2595987","DOIUrl":"10.1080/13697137.2025.2595987","url":null,"abstract":"Objective: There are many menopauses; bilateral oophorectomy is associated with the worst cognitive outcomes. Compared to females with intact ovaries, females with bilateral oophorectomy experience early, abrupt ovarian hormone loss and are at increased risk for later-life Alzheimer's disease. They also have double the odds of developing later-life sleep disordered breathing (SDB) - a modifiable Alzheimer's risk factor. With respect to bilateral oophorectomy, it is unknown when respiratory disturbances occur or whether estradiol therapy (ET) ameliorates them. Also unknown is whether SDB influences cognition in this group.Method: Females with risk-reducing bilateral salpingo-oophorectomy (BSO) taking ET (BSO+ET, n = 19) or not (BSO, n = 16) and premenopausal age-matched controls (AMC, n = 17) were assessed for SDB markers using take-home polysomnography and for working memory performance.Results: The BSO group showed signs of respiratory disturbance compared to the AMC group. Memory performance was uncorrelated with respiratory metrics. While the BSO+ET group showed an intermediate sleep phenotype, estrone glucuronide levels correlated with improved respiratory metrics.Conclusion: The results suggest that respiratory disturbances manifest as early as 5 years post-BSO in younger females; ET offers some amelioration. The close relationship between sleep disruption and Alzheimer's risk emphasizes the importance of SDB screening post-BSO for early intervention.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"218-226"},"PeriodicalIF":3.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145809724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of age of menarche and menopause on mental health in postmenopausal women: a cross-sectional survey. 初潮和绝经年龄对绝经后妇女心理健康的影响：一项横断面调查。

IF 3.2 4区医学

Climacteric Pub Date : 2026-04-01 Epub Date: 2025-11-17 DOI: 10.1080/13697137.2025.2577744

Yali Wang, Xiaotian Liu, Huanxiang Zhang, Zixu Li, Jian Zhang, Xiuli Tang, Jia Qiu, Huimin Qu, Bing Zhao, Chongjian Wang

{"title":"Effects of age of menarche and menopause on mental health in postmenopausal women: a cross-sectional survey.","authors":"Yali Wang, Xiaotian Liu, Huanxiang Zhang, Zixu Li, Jian Zhang, Xiuli Tang, Jia Qiu, Huimin Qu, Bing Zhao, Chongjian Wang","doi":"10.1080/13697137.2025.2577744","DOIUrl":"10.1080/13697137.2025.2577744","url":null,"abstract":"Objective: The aim of this study was to explore the independent and combined effects of age at menarche (AAM) and age at natural menopause (ANM) on postmenopausal women's mental health and to evaluate healthy life expectancy (HLE) in different AAM and ANM groups based on mental disease dimensions.Method: Logistic regression was used to assess the associations of AAM and ANM with mental health. A period life table was used to calculate life expectancy, and HLE was calculated via the Sullivan method.Results: A total of 11,908 postmenopausal women were included in this study. Compared with menarche at 12-15 years, multiple adjusted odds ratios (95% confidence intervals) for depression, anxiety and mental disorder were 2.313 (1.079, 4.960), 2.401 (1.161, 4.966) and 2.103 (1.051, 4.205) for menarche age <12 years and 1.219 (1.013, 1.468), 1.244 (1.039, 1.491) and 1.210 (1.029, 1.421) for menarche age >15 years; early menopause was associated with depression and anxiety compared to the normal range of ANM. The early AAM and ANM groups tended to have the lowest HLE.Conclusion: Abnormal AAM and ANM are not only associated with increased risk of mental problems, but also affect mental HLE in postmenopausal women.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"277-284"},"PeriodicalIF":3.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145539421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

'Menopausando': a digital health education platform for women in the transition to menopause and postmenopause. “绝经”：面向绝经期和绝经后过渡妇女的数字健康教育平台。

IF 3.2 4区医学

Climacteric Pub Date : 2026-04-01 Epub Date: 2025-09-09 DOI: 10.1080/13697137.2025.2548798

Maély de Oliveira Ignácio, Mariana Gomes Martins, Caio Fábio Schlechta Portella, Aline Evangelista Santiago, Juliana Zangirolami-Raimundo, Edmund Chada Baracat, José Maria Soares, Isabel Cristina Esposito Sorpreso

{"title":"'Menopausando': a digital health education platform for women in the transition to menopause and postmenopause.","authors":"Maély de Oliveira Ignácio, Mariana Gomes Martins, Caio Fábio Schlechta Portella, Aline Evangelista Santiago, Juliana Zangirolami-Raimundo, Edmund Chada Baracat, José Maria Soares, Isabel Cristina Esposito Sorpreso","doi":"10.1080/13697137.2025.2548798","DOIUrl":"10.1080/13697137.2025.2548798","url":null,"abstract":"Objective: Social media is an increasingly relevant tool for health education, enabling information exchange, promoting autonomy and supporting informed decision-making. This study introduces Menopausando, a predominantly Portuguese-language digital platform designed to support women during menopausal transition and postmenopause.Method: This cross-sectional study has been carried out in the Gynecology Discipline, São Paulo University, Brazil, since 2019. In the pre-implementation phase of the digital platform, interviews were conducted with 287 Internet users about their experiences and preferences to be disclosed on the digital platform. The chi-square test or Fisher's exact test and analysis of variance with Stata 16 SE were utilized.Results: Interviewees were 83.3% white with mean age 54.3 (1.82) years, and 78.8% were interested in a menopause digital platform. The platform reached 21,617 website users, 3048 Instagram users, 133 Facebook users and 1126 Spotify users. Facebook users were older, men age 51.3 (9.3) years, than Spotify users, mean age 45.6 (12.2) years (p < 0.001). Female gender was present in all social networks (p < 0.001). The largest number of Brazilian users was on the website, with 21,000 (97.1%) (p < 0.001) (all groups), and other countries' websites and Instagram (p < 0.001).Conclusion: Menopausando effectively supports women during menopausal transition and postmenopause via multiple digital channels. The results expose digital access tendencies and inequalities.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"263-269"},"PeriodicalIF":3.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of menopausal hormone therapy usage in symptomatic postmenopausal women in Australia. 在澳大利亚有症状的绝经后妇女中使用绝经期激素治疗的患病率。

IF 3.2 4区医学

Climacteric Pub Date : 2026-04-01 Epub Date: 2025-12-15 DOI: 10.1080/13697137.2025.2584064

Julia Grant, Molly Bond, Rakibul M Islam, Susan R Davis

{"title":"Prevalence of menopausal hormone therapy usage in symptomatic postmenopausal women in Australia.","authors":"Julia Grant, Molly Bond, Rakibul M Islam, Susan R Davis","doi":"10.1080/13697137.2025.2584064","DOIUrl":"10.1080/13697137.2025.2584064","url":null,"abstract":"Objective: This study aimed to report the prevalence of menopausal hormone therapy (MHT) usage in symptomatic postmenopausal women in Australia.Method: The Australian Midlife Years Study is a nationally representative, cross-sectional questionnaire-based study of women aged 40-69 years that included current MHT usage and menopausal symptoms. Data were collected during October 2023-March 2024.Results: Of 8086 participants, 10.8% of postmenopausal respondents reported MHT use. Further analysis was limited to 2503 potential MHT users (postmenopausal with vasomotor symptoms; 77.5%, n = 1941) or current users (22.5%; n = 562). The absolute number of MHT users was greatest amongst those aged 50-59 years (n = 309/1304, 24%), but the greatest proportion of use was amongst those aged 40-49 years (96/319, 30%). MHT use was less likely for participants who had body mass index (BMI) of 18.5 kg/m2 or ≥30 kg/m2 versus BMI of 18.5-29.9 kg/m2 (p < 0.05 for all), were smokers (p < 0.001), were unemployed but seeking work versus in paid employment (p = 0.003) or were of non-European ancestry (p < 0.05). Education beyond high school (p = 0.002) and past hysterectomy and/or oophorectomy were associated with greater likelihoods of MHT use (p < 0.001).Conclusions: Fewer than one-quarter of symptomatic postmenopausal Australian women were using MHT, with socio-demographic variables predicting use. The overall use remains similar to that reported a decade ago.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"210-217"},"PeriodicalIF":3.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145755378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MenoPROMPT: co-design of a digital menopause pre-consultation tool for Australian general practice. MenoPROMPT：澳大利亚全科实践的数字更年期预咨询工具的共同设计。

IF 3.9 4区医学

Climacteric Pub Date : 2026-04-01 Epub Date: 2025-11-17 DOI: 10.1080/13697137.2025.2576471

Caroline McBride, Barbara Hunter, Erin Davis, Rita McMorrow, Jo-Anne Manski-Nankervis

{"title":"MenoPROMPT: co-design of a digital menopause pre-consultation tool for Australian general practice.","authors":"Caroline McBride, Barbara Hunter, Erin Davis, Rita McMorrow, Jo-Anne Manski-Nankervis","doi":"10.1080/13697137.2025.2576471","DOIUrl":"10.1080/13697137.2025.2576471","url":null,"abstract":"Objective: This study aimed to explore the needs and preferences of women and general practitioners (GPs) in relation to a menopause-related digital pre-consultation screening tool to be used in Australian general practice.Method: The qualitative co-design design study brought together GPs and women with lived experience of menopause symptoms to develop a prototype for a digital pre-consultation screening tool for menopause symptoms.Results: Twelve participants worked together to co-design a pre-consultation questionnaire. Themes highlighted the barriers around starting conversations about menopause, and the importance of normalizing these discussions. Participants envisioned that a well-designed pre-consultation tool could help address these needs. A prototype of the tool was successfully co-designed, receiving consensus agreement from all participants. Key elements of the tool include the use of signposting, clear language and logical sequencing of questions.Conclusion: The tool will be trialed in a pilot implementation study in 10 general practice clinics over a period of 12 months. Qualitative interviews will focus on the tool's functionality and workflow in practice.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"270-276"},"PeriodicalIF":3.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145539432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0