IF 2.9 4区医学

Climacteric Pub Date : 2025-05-22 DOI: 10.1080/13697137.2025.2503880

Ruiyi Tang, Qingyuan Liu, Qi Yu

引用次数: 0

Genitourinary syndrome of menopause: a multicenter study from the Indian Midlife Registry. 绝经期泌尿生殖系统综合征：一项来自印度中年登记处的多中心研究。

IF 2.9 4区医学

Climacteric Pub Date : 2025-05-21 DOI: 10.1080/13697137.2025.2496681

Asna Beg Ashraf, Meeta Meeta, A B Chitra, Sangeeta Pahwa, Jyoti Shah, Manjit Mohi, Geeta Reddy, Kiran Aggarwal, Amrita Sarkari, Sudha Sharma, Jyoti Jaiswal, Jignesh Shah, Bipasa Sen, Jyothi Unni, Sheela Mane, Jyothika Desai

{"title":"Genitourinary syndrome of menopause: a multicenter study from the Indian Midlife Registry.","authors":"Asna Beg Ashraf, Meeta Meeta, A B Chitra, Sangeeta Pahwa, Jyoti Shah, Manjit Mohi, Geeta Reddy, Kiran Aggarwal, Amrita Sarkari, Sudha Sharma, Jyoti Jaiswal, Jignesh Shah, Bipasa Sen, Jyothi Unni, Sheela Mane, Jyothika Desai","doi":"10.1080/13697137.2025.2496681","DOIUrl":"https://doi.org/10.1080/13697137.2025.2496681","url":null,"abstract":"Objective: This study aimed to investigate the prevalence and characteristics of genitourinary syndrome of menopause (GSM) in midlife women.Methods: The cross-sectional study from the Indian Midlife Registry included women aged >40 years attending outpatient clinics at multiple centers across India. Real-world data were collected on an Electronic Health Record platform. GSM was diagnosed in the presence of either two genitourinary or sexual symptoms or one symptom and a Vaginal Health Index (VHI) score of ≤15.Results: A total of 1781 women, 826 perimenopausal and 955 postmenopausal, were included. The prevalence of GSM was 48.5%, and the most prevalent symptoms were lower urinary tract symptoms (LUTS) (38.2%) and vaginal dryness (26.4%). The VHI score was ≤15 in 42.1% of women. Based on logistic regression analysis, age ≥70 years, late postmenopause, low education, insomnia and other sleep problems were associated with higher odds of GSM.Conclusion: GSM is highly prevalent in Indian women. GSM remains under-recognized and undertreated. Sleep problems, advanced age, late postmenopause and low education significantly increase the odds. This study underscores the importance of routine screening for GSM, especially in those with sleep disturbances or LUTS in order to improve quality of life (QoL).","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-8"},"PeriodicalIF":2.9,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obesity indices and cardiometabolic diseases in postmenopausal women in Ilorin, Nigeria. 尼日利亚伊洛林绝经后妇女的肥胖指数和心脏代谢疾病

IF 2.9 4区医学

Climacteric Pub Date : 2025-05-20 DOI: 10.1080/13697137.2025.2496692

Ismaila Aberi Obalowu, Louis Okeibunor Odeigah, Abdulkadir Mohammed, Oyeronke A Oyeleke, Toyin Tawa Odediji, Majidat Funmilayo Amin

{"title":"Obesity indices and cardiometabolic diseases in postmenopausal women in Ilorin, Nigeria.","authors":"Ismaila Aberi Obalowu, Louis Okeibunor Odeigah, Abdulkadir Mohammed, Oyeronke A Oyeleke, Toyin Tawa Odediji, Majidat Funmilayo Amin","doi":"10.1080/13697137.2025.2496692","DOIUrl":"https://doi.org/10.1080/13697137.2025.2496692","url":null,"abstract":"Objective: Obesity is a known risk factor for the development of cardiometabolic diseases (CMD) globally. The study focus was finding the best predictor of CMD among the four anthropometric indices of obesity studied: body mass index (BMI), waist to hip ratio (WHR), waist to height ratio (WHtR) and visceral adiposity index (VAI).Method: A total of 310 postmenopausal women participated in the study. Sociodemographic data, anthropometric measurements, serum high-density lipoprotein and serum triglycerides were taken for all participants. The receiver operating characteristic curve was used to detect the valid cut-off point for the VAI.Results: The VAI cut-off point for diagnosing visceral adiposity dysfunction (VAD) in the study was >1.92. The prevalence of peripheral obesity in the study was 18.1%, while that of truncal obesity was 76.5% using the WHR and 81.9% using the WHtR. The prevalence of CMD in the study was 51.6% while that for VAD was 60.3%. The WHtR (p = 0.041) and the VAI (p < 0.001) had statistically significant associations with the presence of CMD among the participants but only the VAI was found to be a significant predictor of CMD.Conclusion: We recommend use of the VAI for CMD screening among postmenopausal women.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-6"},"PeriodicalIF":2.9,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Menopausal symptoms and risk factors in Chinese women: a multicenter cross-sectional study. 中国妇女更年期症状和危险因素：一项多中心横断面研究

IF 2.9 4区医学

Climacteric Pub Date : 2025-05-20 DOI: 10.1080/13697137.2025.2500563

Ruiyi Tang, Qingyuan Liu, Jie Li, Mei Li, Hongxia Wang, Qi Yu

{"title":"Menopausal symptoms and risk factors in Chinese women: a multicenter cross-sectional study.","authors":"Ruiyi Tang, Qingyuan Liu, Jie Li, Mei Li, Hongxia Wang, Qi Yu","doi":"10.1080/13697137.2025.2500563","DOIUrl":"https://doi.org/10.1080/13697137.2025.2500563","url":null,"abstract":"Objective: This study aimed to examine menopausal symptoms and their associated factors among premenopausal, perimenopausal and postmenopausal groups of middle-aged Chinese women.Methods: The nationwide cross-sectional study involved 9740 middle-aged women from 115 medical centers across 27 provinces in China. Logistic regression analyses were performed to explore the associations between menopausal symptom severity and age, menopausal status, body mass index (BMI), smoking, employment status, income, education level, exercise and alcohol use.Results: Among the 9740 participants, 17.6% (n = 1711) were premenopausal, 38.3% (n = 3730) were perimenopausal and 44.1% (n = 4299) were postmenopausal. The likelihood of moderate to severe menopausal symptoms was positively associated with age (odds ratio [OR] 1.10; 95% confidence interval [CI] 1.09-1.11; p < 0.001), perimenopause (OR 2.15; 95% CI 1.90-2.45; p < 0.001) and postmenopausal stage (OR 5.96; 95% CI 5.25-6.77; p < 0.001), smoking (OR 1.96; 95% CI 1.39-2.77; p < 0.001) and unemployment (OR 1.47; 95% CI 1.31-1.65; p < 0.001). In contrast, higher income was inversely associated with symptom severity (OR 0.69; 95% CI 0.58-0.82; p < 0.001). BMI demonstrated a positive association with symptom severity in premenopausal women.Conclusions: Age, menopausal status, smoking, unemployment and lower income were associated with more severe menopausal symptoms.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-7"},"PeriodicalIF":2.9,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Variations in the prevalence of premature and early menopause in low and middle-income regions: a cross-sectional study. 低收入和中等收入地区过早和早期绝经患病率的变化：一项横断面研究。

IF 2.9 4区医学

Climacteric Pub Date : 2025-05-19 DOI: 10.1080/13697137.2025.2500561

Sydney Ross, Sol P Juárez

{"title":"Variations in the prevalence of premature and early menopause in low and middle-income regions: a cross-sectional study.","authors":"Sydney Ross, Sol P Juárez","doi":"10.1080/13697137.2025.2500561","DOIUrl":"https://doi.org/10.1080/13697137.2025.2500561","url":null,"abstract":"Objective: This study aimed to examine differences in premature and early menopause across various regions in low and middle-income countries (LMICs).Methods: Data for 55 LMICs from the Demographic and Health Surveys (2013-2023) were classified into nine regions. Proportions of premature (aged <40 years) and early (aged <45 years) menopause were calculated. Logistic regressions adjusted for covariates were also run.Results: The proportion of women in premature menopause ranged from 1.58% in the European and Eastern Mediterranean regions to 6.87% in Southern Africa. For early menopause, proportions ranged from 4.92% in the Eastern Mediterranean region to 15.21% in the Americas. The Eastern Mediterranean region had systematic lower odds across menopause categories, even after the adjustments for relevant covariates.Conclusion: Significant variation exists in the proportion of the different age at menopause categories within LMIC regions. Higher proportions of premature and early menopause were found in all LMIC regions compared to those reported in current literature from high-income countries. A global health perspective on menopause is urgently needed, especially in relation to the increased disease risks with early and premature menopause, such as cardiovascular disease.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-5"},"PeriodicalIF":2.9,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genitourinary syndrome of menopause among Chinese women during the menopausal transition and postmenopause: findings from a longitudinal cohort study. 中国妇女绝经过渡期和绝经后的泌尿生殖系统综合征：一项纵向队列研究的结果。

IF 2.9 4区医学

Climacteric Pub Date : 2025-05-16 DOI: 10.1080/13697137.2025.2497427

Yubo Fan, Jingbo Huang, Feiling Huang, Ruiyi Tang, Penghui Feng, Xuanjin Yang, Zhuolin Xie, Lingjin Yang, Xiaonan Ma, Keyang Yang, Rong Chen

{"title":"Genitourinary syndrome of menopause among Chinese women during the menopausal transition and postmenopause: findings from a longitudinal cohort study.","authors":"Yubo Fan, Jingbo Huang, Feiling Huang, Ruiyi Tang, Penghui Feng, Xuanjin Yang, Zhuolin Xie, Lingjin Yang, Xiaonan Ma, Keyang Yang, Rong Chen","doi":"10.1080/13697137.2025.2497427","DOIUrl":"https://doi.org/10.1080/13697137.2025.2497427","url":null,"abstract":"Objective: This study aims to explore the prevalence and related factors of genitourinary syndrome of menopause (GSM) in a Chinese longitudinal cohort.Method: A total of 616 women in the menopausal transition or postmenopausal stage from an urban Chinese community were included in this study. The study assessed the prevalence, degree and factors associated with different types of GSM.Results: The prevalence of moderate/severe GSM rose from 23.9% in the early menopausal transition to 36.8% in the late menopausal transition, to 56.1% in postmenopause stage +1 and 71.4% in postmenopause stage +2. More than half of the postmenopausal women reported loss of libido (68.7%), vaginal dryness (60.2%), stress urinary incontinence (59.8%) and low sexual pleasure (58.8%). Multivariable analysis revealed that Stages of Reproductive Aging Workshop +10 (STRAW +10) stages (p = 0.009), marital status (p < 0.001) and anxiety (p = 0.005) were independently associated with GSM.Conclusion: This study shows that as women progress through the menopausal transition, GSM symptoms become increasingly common and severe. In particular, postmenopausal women experience a higher burden of these symptoms. Additionally, menopausal stage, marital status and anxiety were identified as independent factors associated with GSM. These findings provide a comprehensive insight of GSM among middle-aged Chinese women, underlining the importance of diagnosis and treatment for GSM.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-10"},"PeriodicalIF":2.9,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heart matters: the unique landscape of cardiovascular health in women. 心脏问题：女性心血管健康的独特景观。

IF 2.9 4区医学

Climacteric Pub Date : 2025-05-16 DOI: 10.1080/13697137.2025.2497419

Gemma A Figtree, Michael P Gray

引用次数: 0

Premature ovarian insufficiency: addressing the most controversial issues. 卵巢功能不全：解决最具争议的问题。

IF 2.9 4区医学

Climacteric Pub Date : 2025-05-16 DOI: 10.1080/13697137.2025.2497415

Nick Panay

{"title":"Premature ovarian insufficiency: addressing the most controversial issues.","authors":"Nick Panay","doi":"10.1080/13697137.2025.2497415","DOIUrl":"https://doi.org/10.1080/13697137.2025.2497415","url":null,"abstract":"It was a true honor to be invited as President to deliver the Pieter Van Keep oration at the 2024 International Menopause Society (IMS) Congress in Melbourne, Australia. There was never any doubt that the topic of my lecture would be premature ovarian insufficiency (POI). POI is a condition which has been neglected for far too long given its greater global prevalence than originally estimated and its implications to the sufferers, both in terms of quality of life and long-term well-being. The hope is that we are now entering a new era of awareness given the recent update of the European Society of Human Reproduction (ESHRE) POI guideline, achieved through a partnership of the ESHRE, American Society for Reproductive Medicine (ASRM), Centre for Research Excellence in Women's Health in Reproductive Life (CRE WHiRL) at Monash University and IMS with support from numerous global stakeholder organizations. Whilst as a minimum the update of the guideline is expected to improve clinical management of this condition, the process has also identified key areas of much-needed research, where currently only practical guidance can be given due to the lack of data. The aim of my Pieter Van Keep lecture, and therefore this article, was not to replicate the extensive work already conducted to systematically review the literature for the guideline. The aim was to provide a state-of-the-art commentary highlighting the key controversial topics regarding this distressing condition, and how these are being addressed, or should be addressed in the future, for the sake of sufferers and their families.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-7"},"PeriodicalIF":2.9,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The influence of HIV on body composition and its relationship with physical function in mid-life women: a cross-sectional study from Zimbabwe. 艾滋病毒对中年妇女身体成分的影响及其与身体功能的关系：来自津巴布韦的横断面研究。

IF 2.9 4区医学

Climacteric Pub Date : 2025-05-14 DOI: 10.1080/13697137.2025.2496685

Mícheál Ó Breasail, Jakub Mesinovic, Tafadzwa Madanhire, Cynthia Kahari, Peter R Ebeling, Victoria Simms, Rashida A Ferrand, Kate A Ward, Celia L Gregson

{"title":"The influence of HIV on body composition and its relationship with physical function in mid-life women: a cross-sectional study from Zimbabwe.","authors":"Mícheál Ó Breasail, Jakub Mesinovic, Tafadzwa Madanhire, Cynthia Kahari, Peter R Ebeling, Victoria Simms, Rashida A Ferrand, Kate A Ward, Celia L Gregson","doi":"10.1080/13697137.2025.2496685","DOIUrl":"https://doi.org/10.1080/13697137.2025.2496685","url":null,"abstract":"Objective: Menopause-related changes in body composition and physical function are unclear in Southern Africa, particularly in the context of a generalized HIV epidemic with high antiretroviral therapy (ART) coverage.Method: A total of 263 Zimbabwean women (53% women living with HIV [WLH]) aged 40-60 years provided data on menopause, ART use, anthropometry, body composition (appendicular lean mass [ALM], muscle area, fat mass), handgrip strength (HGS) and gait speed. Linear regression determined relationships between body composition and physical function, unadjusted and age-menopause-adjusted, stratified by HIV status. Univariate logistic regression investigated associations between body composition and self-reported falls.Results: WLH (96% ART established) were a median (interquartile range) 10.4 (6.4-14.5) years since diagnosis, with lower weight, body mass index, ALM, fat mass and HGS than women living without HIV (WLWOH). With menopause transition, WLH lost weight, ALM, gynoid mass and muscle area (all p-trend <0.05); however, WLWOH did not. Both WLH and WLWOH lost HGS (p-trend <0.05). ALM was positively associated with HGS in all women. In WLH, greater percentage body fat, particularly gynoid fat, was associated with increased odds of falls (1.69 [1.00-2.89], p = 0.049 and 1.72 [1.08-2.75], p = 0.023, respectively).Conclusion: Women living with HIV were more likely to experience adverse changes in body composition through menopause; fat mass gains were associated with risk of falls.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-9"},"PeriodicalIF":2.9,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Profile and risk stratification for sarcopenia in postmenopausal women. 绝经后妇女肌肉减少症的概况和危险分层。

IF 2.9 4区医学

Climacteric Pub Date : 2025-05-14 DOI: 10.1080/13697137.2025.2495310

Marcelo Luis Steiner, Larissa Gabrielli Lima de Campos, Marina Martinelli Sonnenfeld, Tayná Gueler Silva, Mariliza Henrique da Silva, Rodolfo Strufaldi, Cesar Eduardo Fernandes, Luciano de Melo Pompei

{"title":"Profile and risk stratification for sarcopenia in postmenopausal women.","authors":"Marcelo Luis Steiner, Larissa Gabrielli Lima de Campos, Marina Martinelli Sonnenfeld, Tayná Gueler Silva, Mariliza Henrique da Silva, Rodolfo Strufaldi, Cesar Eduardo Fernandes, Luciano de Melo Pompei","doi":"10.1080/13697137.2025.2495310","DOIUrl":"https://doi.org/10.1080/13697137.2025.2495310","url":null,"abstract":"Objective: This study aimed to assess the risk factors associated with sarcopenia and identify risk profiles through cluster analysis in postmenopausal women treated at specialized outpatient clinics.Methods: A retrospective cross-sectional study evaluated data from 287 postmenopausal women. Sarcopenia was determined by handgrip and gait speed testing. Cluster analysis was applied to identify risk subgroups, and logistic regression to identify factors associated with sarcopenia.Results: Sarcopenia was identified in 18.50% of women. Advanced age (odds ratio [OR] = 1.12; 95% confidence interval [CI]: 1.07-1.16; p < 0.01), number of pregnancies (OR = 1.14; 95% CI: 1.00-1.29; p = 0.04), hip Fracture Risk Assessment Tool (FRAX) (OR = 1.29; 95% CI: 1.12-1.49; p < 0.01), systemic arterial hypertension (OR = 3.20; 95% CI: 1.66-6.17; p < 0.01) and multiple comorbidities (OR = 2.46; 95% CI: 1.19-5.09, p = 0.01) were associated with higher risk for sarcopenia. Cluster analysis revealed an increased risk profile for women who were aged over 70 years, multiparous, hypertensive, with hip FRAX greater than 3% and with major fractures greater than 6%.Conclusion: Postmenopausal women with sarcopenia are more likely to have fragility fractures at 10 years, to be older, multiparous and hypertensive, and to have multiple comorbidities.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-7"},"PeriodicalIF":2.9,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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