Climacteric最新文献_第2页

Intraocular pressure and central corneal thickness in premenopausal and postmenopausal women: a systematic review and meta-analysis. 绝经前和绝经后妇女的眼压和中央角膜厚度：一项系统回顾和荟萃分析。

IF 3.2 4区医学

Climacteric Pub Date : 2025-08-14 DOI: 10.1080/13697137.2025.2539856

Parva Pourbagherkhah, Mohammad Farjami, Hemn Baghban Jaldian

{"title":"Intraocular pressure and central corneal thickness in premenopausal and postmenopausal women: a systematic review and meta-analysis.","authors":"Parva Pourbagherkhah, Mohammad Farjami, Hemn Baghban Jaldian","doi":"10.1080/13697137.2025.2539856","DOIUrl":"https://doi.org/10.1080/13697137.2025.2539856","url":null,"abstract":"Objective: This study aimed to systematically evaluate and quantify the impact of menopausal status on intraocular pressure (IOP) and central corneal thickness (CCT) in women, through a comparative meta-analysis.Method: A systematic search was conducted across PubMed, Scopus, Web of Science and the Cochrane Library up to 15 April 2025, following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Eligible studies included original research comparing IOP and/or CCT between premenopausal and postmenopausal women. Meta-analysis was conducted using a random-effects model, and heterogeneity was assessed via I2, τ2 and H2 statistics.Results: Ten studies were analyzed in this meta-analysis, including data from premenopausal and postmenopausal women (totaling 999 eyes). The pooled results indicated that postmenopausal women had significantly higher IOP and reduced CCT compared to premenopausal women. Despite high heterogeneity (I2 = 97.17% for CCT, I2 = 84.20% for IOP), the direction of effect was consistent across most studies. The hormonal decline associated with menopause, particularly reduced estrogen levels, appears to affect corneal structure.Conclusion: Menopause is associated with elevated IOP and decreased CCT, likely due to hormonal alterations, notably estrogen deficiency. Menopausal status may be a relevant factor in ocular assessments and could have implications for risk assessment in conditions such as glaucoma.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-6"},"PeriodicalIF":3.2,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sarcopenia and sarcopenic obesity in postmenopausal women: a cross-sectional study in Türkiye. 绝经后妇女的肌肉减少症和肌肉减少性肥胖：一项在日本的横断面研究。

IF 3.2 4区医学

Climacteric Pub Date : 2025-08-14 DOI: 10.1080/13697137.2025.2537982

Aylin Yılmaz, Nurdan Şentürk Durmuş, Yasin Yıldız, Zeynep Beşışık Yılmaz, Çiğdem Alkaç, Büşra Can, Emre Capar, Abidin Gündoğdu, Aslı Tufan

{"title":"Sarcopenia and sarcopenic obesity in postmenopausal women: a cross-sectional study in Türkiye.","authors":"Aylin Yılmaz, Nurdan Şentürk Durmuş, Yasin Yıldız, Zeynep Beşışık Yılmaz, Çiğdem Alkaç, Büşra Can, Emre Capar, Abidin Gündoğdu, Aslı Tufan","doi":"10.1080/13697137.2025.2537982","DOIUrl":"https://doi.org/10.1080/13697137.2025.2537982","url":null,"abstract":"Objective: Sarcopenia is a multifactorial skeletal muscle disease commonly observed in the geriatric population. It is influenced by hormonal changes that occur during the postmenopausal period. This study aims to evaluate the sarcopenia status of postmenopausal women.Method: The study included 300 postmenopausal women. Sarcopenia was defined according to the updated European Working Group on Sarcopenia in Older People (EWGSOP-2) definition.Results: Of the evaluated patients, 44.7% (n = 134) and 15.4% (n = 46) were sarcopenic and sarcopenic obese, respectively. Older age, the number of chronic diseases, medications used and the status of polypharmacy were significantly higher in the sarcopenic group (all p < 0.050). Non-obese patients with sarcopenia showed greater dependence in activities of daily living (ADLs) (p = 0.002) and instrumental ADLs (IADLs) (p = 0.001). In ADLs (p = 0.001) and IADLs (p = 0.001), non-sarcopenic obese patients showed greater independence. Postmenopausal sarcopenia was related to older age (hazard ratio [HR]: 1.07, 95% confidence interval (CI): [1.04-1.10]; p < 0.001), the presence of osteoporosis (HR: 1.86, 95% CI: [1.05-3.30]; p = 0.034) and the existence of vasomotor symptoms (HR: 2.30, 95% CI: [1.31-4.04]; p = 0.004).Conclusion: This study highlights the importance of sarcopenia awareness among specialists providing healthcare services to postmenopausal patients. The study underscores the significance of initiating preventive and treatment strategies for at-risk patients before they reach old age.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-6"},"PeriodicalIF":3.2,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleep disorders and menopausal symptoms: a Latin American perspective on postmenopausal health. 睡眠障碍和更年期症状：拉丁美洲对绝经后健康的看法。

IF 3.2 4区医学

Climacteric Pub Date : 2025-08-13 DOI: 10.1080/13697137.2025.2537979

Eugenio E Arteaga, Juan E Blümel, María S Vallejo, Carlos Salinas, Konstantinos Tserotas, Andrés Calle, Maribel Dextre, Alejandra Elizalde, María T Espinoza, Carlos Escalante, Gustavo Gómez-Tabares, Alejandra Martínez-García, Álvaro Monterrosa-Castro, Mónica Ñañez, Eliana Ojeda, Claudia Rey, Doris Rodríguez-Vidal, Marcio A Rodrígues

{"title":"Sleep disorders and menopausal symptoms: a Latin American perspective on postmenopausal health.","authors":"Eugenio E Arteaga, Juan E Blümel, María S Vallejo, Carlos Salinas, Konstantinos Tserotas, Andrés Calle, Maribel Dextre, Alejandra Elizalde, María T Espinoza, Carlos Escalante, Gustavo Gómez-Tabares, Alejandra Martínez-García, Álvaro Monterrosa-Castro, Mónica Ñañez, Eliana Ojeda, Claudia Rey, Doris Rodríguez-Vidal, Marcio A Rodrígues","doi":"10.1080/13697137.2025.2537979","DOIUrl":"10.1080/13697137.2025.2537979","url":null,"abstract":"Objective: This cross-sectional, observational study, conducted in nine Latin American countries, aimed to examine the association between hot flashes and insomnia, and whether the severity of vasomotor symptoms (VMS) correlates with sleep disturbances.Method: The study collected sociodemographic and clinical data, and evaluated the presence of sleep disorders using Jenkin's Sleep Scale (JSS-4) and menopausal symptoms using the Menopause Rating Scale (MRS) questionnaire.Results: The study included 1185 postmenopausal women with average age 56.9 ± 5.7 years, body mass index (BMI) of 26.5 ± 5.2 kg/m² and 8.6 ± 6.4 years since menopause. Overall, 20.6% reported sleep disturbances. Compared to those without sleep problems, affected women had longer postmenopausal duration (12 ± 9.0 vs. 10.8 ± 7.8, p < 0.03), had higher BMI (27.9 ± 5.6 vs. 26.1 ± 5.0, p < 0.001), were more often smokers and homemakers, and had more comorbidities. They were also less likely to have a partner or have used menopausal hormone therapy. Sleep disturbances increased proportionally with VMS severity (p < 0.01). In multivariate analysis, sleep disorders were associated with VMS (odds ratio [OR] 4.47), psychotropic use (OR 1.84), obesity (OR 1.45) and comorbidities (OR 1.45).Conclusion: Women with VMS were more likely to experience sleep disorders and this effect was proportional to the magnitude of the hot flashes. The study also presents several factors associated with sleep disorders in postmenopausal women that should be considered to help prevent these disturbances.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-7"},"PeriodicalIF":3.2,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144844728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sexual difficulties, distress and dysfunction among women with refugee background in Australia. 澳大利亚难民背景妇女的性困难、苦恼和性功能障碍。

IF 3.2 4区医学

Climacteric Pub Date : 2025-08-07 DOI: 10.1080/13697137.2025.2537973

Maryam Jahangirifar, Susan R Davis, Ensieh Fooladi, Rakibul M Islam

{"title":"Sexual difficulties, distress and dysfunction among women with refugee background in Australia.","authors":"Maryam Jahangirifar, Susan R Davis, Ensieh Fooladi, Rakibul M Islam","doi":"10.1080/13697137.2025.2537973","DOIUrl":"https://doi.org/10.1080/13697137.2025.2537973","url":null,"abstract":"Objective: This study aimed to document the prevalence of sexual difficulties, sexually-related personal distress, sexual dysfunction and associated factors among refugee women in Australia.Method: The cross-sectional study included refugee women aged 18-63 years. Sexual difficulties were defined as selecting 'always' or 'very often' on the Profile of Female Sexual Function, while distress was a score of at least 11 on the Female Sexual Distress Scale - Revised. Female sexual dysfunction (FSD) combined these scores. Participants also completed the Woman Abuse Screening Tool and the Bristol Female Lower Urinary Tract Symptoms questionnaire.Results: Among 299 participants (median age 41 years), sexual difficulties, sexually-related personal distress and FSD were present in 39.3%, 33.2% and 7.0%, respectively. Perimenopausal/postmenopausal status (adjusted odds ratio [aOR] = 2.8, 95% confidence interval [CI]: 1.4-5.6, p = 0.003) and sexual activity (aOR = 0.2, 95% CI: 0.1-0.4, p < 0.001) predicted sexual difficulties. Intimate partner abuse (aOR = 5.9, 95% CI: 2.4-14.5, p < 0.001) and urinary incontinence (aOR = 4.5, 95% CI: 1.5-13.0, p = 0.006) were associated with sexually-related personal distress.Conclusion: Perimenopausal/postmenopausal status and sexual inactivity were associated with sexual difficulties, while intimate partner abuse and urinary incontinence were associated with sexually-related distress, highlighting the importance of proactive screening for psychosocial and physical health issues in sexual health assessments among refugee women.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-10"},"PeriodicalIF":3.2,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144798329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction. 修正。

IF 3.2 4区医学

Climacteric Pub Date : 2025-08-07 DOI: 10.1080/13697137.2025.2543631

引用次数: 0

Major adverse cardiovascular events risk in menopausal women treated with oral estradiol/micronized progesterone versus conjugated estrogens/medroxyprogesterone: a claims data analysis in the USA. 口服雌二醇/微粉孕酮与结合雌激素/甲羟孕酮治疗绝经妇女的主要不良心血管事件风险：美国的一项索赔数据分析

IF 3.2 4区医学

Climacteric Pub Date : 2025-08-07 DOI: 10.1080/13697137.2025.2509850

John C Stevenson, Rodney Baber, Risa Kagan, Rossella E Nappi, Santiago Palacios, Nick Panay, Tomasz Paszkowski, Petra Stute, Julie Heroux, Renata Zablotna-Pociupany, Mitra Boolell

{"title":"Major adverse cardiovascular events risk in menopausal women treated with oral estradiol/micronized progesterone versus conjugated estrogens/medroxyprogesterone: a claims data analysis in the USA.","authors":"John C Stevenson, Rodney Baber, Risa Kagan, Rossella E Nappi, Santiago Palacios, Nick Panay, Tomasz Paszkowski, Petra Stute, Julie Heroux, Renata Zablotna-Pociupany, Mitra Boolell","doi":"10.1080/13697137.2025.2509850","DOIUrl":"https://doi.org/10.1080/13697137.2025.2509850","url":null,"abstract":"Objective: Using real-world data, the current study compared the risk of major adverse cardiovascular events (MACE) between two regulated combined oral hormonal products that are currently available to women in the USA: body-identical oral 17β-estradiol/micronized progesterone (E2/P4) and conjugated equine estrogens/medroxyprogesterone acetate (CEE/MPA).Methods: Women aged ≥40 years treated with E2/P4 or CEE/MPA were selected from a US claims database (April 2019-June 2021). The E2/P4 or CEE/MPA cohorts were defined based on the first dispensation of E2/P4 or CEE/MPA (index) as prescribed in the real world. Women with pre-index MACE hospitalization were excluded. Confounding was controlled via inverse probability of treatment (IPT) weighting. MACE risk was compared between the IPT-weighted cohorts using Cox and Poisson/negative binomial regression models.Results: The E2/P4 and CEE/MPA cohorts included 6520 and 29,426 women respectively (mean follow-up 1.2 and 1.4 years). In the IPT-weighted analyses, MACE rates were 23.5 versus 85.4 per 10,000 women-years among women treated with E2/P4 and CEE/MPA (IPT-weighted incidence rate ratio [IRR] 0.28, 95% confidence interval [CI] 0.17 - 0.45; IPT-weighted hazard ratio [HR] 0.37, 95% CI 0.27 - 0.50).Conclusions: Real-world evidence suggests that the MACE risk is significantly lower among women treated with E2/P4 compared to CEE/MPA.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"1-11"},"PeriodicalIF":3.2,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144798328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bringing sex back into the relationship in midlife couples. 让性重新回到中年夫妻的关系中。

IF 3.2 4区医学

Climacteric Pub Date : 2025-08-01 Epub Date: 2025-04-22 DOI: 10.1080/13697137.2025.2489460

Rossella E Nappi, Lara Tiranini, Ellis Martini, Silvia Martella, Federica Barbagallo, Laura Cucinella

{"title":"Bringing sex back into the relationship in midlife couples.","authors":"Rossella E Nappi, Lara Tiranini, Ellis Martini, Silvia Martella, Federica Barbagallo, Laura Cucinella","doi":"10.1080/13697137.2025.2489460","DOIUrl":"10.1080/13697137.2025.2489460","url":null,"abstract":"Sexual health and sexual well-being are important components of the overall quality of life at midlife, a turning point carrying several biopsychosocial changes. As people age, they are likely to observe a significant increase in sexual difficulties in both sexes affecting every domain of sexual response, and a decline in the frequency of engaging in sexual activity. Women may report hypoactive sexual desire disorder (HSDD) and genitourinary syndrome of menopause (GSM), two very common biologically driven midlife conditions that are often comorbid and may also be influenced by a multitude of individual and contextual risk factors. An appropriate and timely diagnosis is important to avoid chronification of sexual dysfunction that may become refractory to treatment. The therapeutic algorithm comprises a multidisciplinary approach, including pharmacologic and non-pharmacologic management. Individualized treatment is the key to providing integrated care with positive attitudes for the aging couples in order to expand the 'sexspan' of both partners. This article reports our point of view on the topic of midlife sexuality in the context of a stable relationship, as presented at the 19th World Congress on Menopause in Melbourne (Australia) on 22 October 2024.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"408-413"},"PeriodicalIF":3.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of ovarian aging on muscle strength and life quality in various reproductive aging stages. 卵巢衰老对生殖衰老各阶段肌力及生活质量的影响。

IF 3.2 4区医学

Climacteric Pub Date : 2025-08-01 Epub Date: 2025-03-20 DOI: 10.1080/13697137.2025.2470451

Aiyue Luo, Hongyu Li, Xing Lv, Peizhe Zheng, Kehan Lin, Aiting Liang, Shuhong Yang

{"title":"The impact of ovarian aging on muscle strength and life quality in various reproductive aging stages.","authors":"Aiyue Luo, Hongyu Li, Xing Lv, Peizhe Zheng, Kehan Lin, Aiting Liang, Shuhong Yang","doi":"10.1080/13697137.2025.2470451","DOIUrl":"10.1080/13697137.2025.2470451","url":null,"abstract":"Objective: Ovarian aging significantly impacts women's overall aging, affecting various systems including the musculoskeletal system. This study investigates the correlation between ovarian function and handgrip strength (HGS) across reproductive aging stages and their relation to health-related quality of life (HRQoL).Method: A cross-sectional study was conducted with female participants spanning all stages of ovarian function. HGS was measured using a dynamometer, and ovarian function was assessed via hormone levels (estradiol [E2], follicle stimulating hormone [FSH], luteinizing hormone [LH], prolactin [PRL], progesterone [P4] and testosterone). HRQoL was evaluated using the Sarcopenia-specific Quality of Life questionnaire (SarQoL). Data analysis involved analysis of variance and Pearson's correlations, adjusted for confounding factors.Results: The prevalence of possible sarcopenia increased from 3.8% in premenopausal women to 10.3% in postmenopausal women. After adjusting for covariates (age, SarQoL, FSH, LH, FSH/LH ratio, PRL, E2, P4 and testosterone), the negative correlation between HGS and the Kupperman Menopausal Index (KMI) was no longer significant. However, the positive correlation between HGS and the SarQoL remained significant in both the overall population and the postmenopausal group. The negative correlation between HGS and FSH was no longer significant after controlling for age, KMI, LH and E2; however, it persisted after controlling for the SarQoL, FSH/LH ratio, PRL, P4 and testosterone.Conclusion: HGS is positively correlated with the SarQoL and negatively correlated with age in the overall population. No significant association was found between HGS and testosterone, E2, LH or FSH/LH ratio. Further research is needed to clarify the relationship between HGS and the KMI or FSH.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"464-470"},"PeriodicalIF":3.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Not just sex: other roles for testosterone in women. 不仅仅是性：女性体内的睾丸激素还有其他作用。

IF 3.2 4区医学

Climacteric Pub Date : 2025-08-01 Epub Date: 2025-01-17 DOI: 10.1080/13697137.2024.2445301

Susan R Davis

引用次数: 0

Menopause, women and the workplace. 更年期，女性和工作场所。

IF 3.2 4区医学

Climacteric Pub Date : 2025-08-01 Epub Date: 2025-04-09 DOI: 10.1080/13697137.2025.2480591

Karen Walker-Bone, Susan Davis

{"title":"Menopause, women and the workplace.","authors":"Karen Walker-Bone, Susan Davis","doi":"10.1080/13697137.2025.2480591","DOIUrl":"10.1080/13697137.2025.2480591","url":null,"abstract":"This invited review is a synthesis of a plenary lecture presented at International Menopause Society Conference in Melbourne 2024. The focus was to set the historic context within which research about women in the workplace must be approached. It is exciting for occupational health researchers to see expansion of the evidence about health and work but we urge menopause and work researchers to collaborate with occupational health colleagues. The growing literature suggests that most women do not experience problems coping with their menopause in the workplace. Most research, however, fails to consider any workplace factors or even the nature of the job women are needing to do. Where studies have focused on occupational groups, they have focused on nurses or other professional/leadership groups. So far, it appears that women's ability to cope is influenced by the number of symptoms, severity of symptoms, and workplace and personal psychosocial factors. However, the problems with coping may be greater for disadvantaged women doing less well-paid work with less flexibility and autonomy. The same women probably have less access to appropriate advice, treatment and support. Researchers must focus on women at highest risk and take a nuanced approach to optimize support without increasing gender-based discrimination.","PeriodicalId":10213,"journal":{"name":"Climacteric","volume":" ","pages":"423-430"},"PeriodicalIF":3.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0