Sarcopenia and sarcopenic obesity in postmenopausal women: a cross-sectional study in Türkiye.

IF 3.2 4区医学 Q1 OBSTETRICS & GYNECOLOGY

Climacteric Pub Date : 2025-08-14 DOI:10.1080/13697137.2025.2537982

Aylin Yılmaz, Nurdan Şentürk Durmuş, Yasin Yıldız, Zeynep Beşışık Yılmaz, Çiğdem Alkaç, Büşra Can, Emre Capar, Abidin Gündoğdu, Aslı Tufan

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引用次数: 0

Abstract

Objective: Sarcopenia is a multifactorial skeletal muscle disease commonly observed in the geriatric population. It is influenced by hormonal changes that occur during the postmenopausal period. This study aims to evaluate the sarcopenia status of postmenopausal women.

Method: The study included 300 postmenopausal women. Sarcopenia was defined according to the updated European Working Group on Sarcopenia in Older People (EWGSOP-2) definition.

Results: Of the evaluated patients, 44.7% (n = 134) and 15.4% (n = 46) were sarcopenic and sarcopenic obese, respectively. Older age, the number of chronic diseases, medications used and the status of polypharmacy were significantly higher in the sarcopenic group (all p < 0.050). Non-obese patients with sarcopenia showed greater dependence in activities of daily living (ADLs) (p = 0.002) and instrumental ADLs (IADLs) (p = 0.001). In ADLs (p = 0.001) and IADLs (p = 0.001), non-sarcopenic obese patients showed greater independence. Postmenopausal sarcopenia was related to older age (hazard ratio [HR]: 1.07, 95% confidence interval (CI): [1.04-1.10]; p < 0.001), the presence of osteoporosis (HR: 1.86, 95% CI: [1.05-3.30]; p = 0.034) and the existence of vasomotor symptoms (HR: 2.30, 95% CI: [1.31-4.04]; p = 0.004).

Conclusion: This study highlights the importance of sarcopenia awareness among specialists providing healthcare services to postmenopausal patients. The study underscores the significance of initiating preventive and treatment strategies for at-risk patients before they reach old age.

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绝经后妇女的肌肉减少症和肌肉减少性肥胖：一项在日本的横断面研究。

目的：骨骼肌减少症是一种多因素骨骼肌疾病，常见于老年人群。它受绝经后时期荷尔蒙变化的影响。本研究旨在评估绝经后妇女肌肉减少症的状况。方法：研究对象为300名绝经后妇女。肌少症的定义是根据更新的欧洲老年人肌少症工作组（EWGSOP-2）的定义。结果：在评估的患者中，44.7% （n = 134）和15.4% （n = 46）分别为肌肉减少症和肌肉减少性肥胖。肌少症组的年龄、慢性疾病数量、药物使用和多药状态显著高于肌少症组（均p = 0.002）和工具性ADLs (IADLs) （p = 0.001）。在adl （p = 0.001）和iadl （p = 0.001）中，非肌肉减少型肥胖患者表现出更大的独立性。绝经后肌肉减少症与年龄较大有关(风险比[HR]: 1.07, 95%可信区间（CI）： [1.04-1.10]；p p = 0.034)和存在血管舒缩症状(HR: 2.30, 95% CI: [1.31-4.04]；p = 0.004)。结论：本研究强调了为绝经后患者提供保健服务的专家对肌肉减少症认识的重要性。该研究强调了在高危患者步入老年之前启动预防和治疗策略的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Climacteric 医学-妇产科学

CiteScore

1.70

自引率

7.10%

发文量

审稿时长

1 months

期刊介绍： Climacteric is the official journal of the International Menopause Society (IMS). As an international peer-reviewed journal it publishes original research and reviews of all aspects of aging in women. Climacteric was founded by the IMS in 1998 and today has become a leading journal in the publication of peer-reviewed papers on the menopause, climacteric and mid-life health. Topics covered include endocrine changes, symptoms attributed to the menopause and their treatment, hormone replacement and alternative therapies, lifestyles, and the counselling and education of peri- and postmenopausal women. Climacteric, published bimonthly, also features regular invited reviews, editorials and commentaries on recent developments. The editorial review board of Climacteric includes leading scientific and clinical experts in the field of midlife medicine and research and is headed by its Editor-in-Chief, Professor Rod Baber of Australia. He and his team of Associate Editors act independently to set a clear editorial policy, co-ordinate peer review, and ensure a rapid response to submitted papers.