Cerebral cortex最新文献_第8页

The preparation impairs the reinterpretation: insights from EEG-based multivariate pattern analysis. 准备工作妨碍了重新解释：基于脑电图的多变量模式分析的见解。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-07-01 DOI: 10.1093/cercor/bhaf175

Jing Wang, Zhifang Li, Qing Li, Mengke Zhang, Yongqiang Chen, Antao Chen

{"title":"The preparation impairs the reinterpretation: insights from EEG-based multivariate pattern analysis.","authors":"Jing Wang, Zhifang Li, Qing Li, Mengke Zhang, Yongqiang Chen, Antao Chen","doi":"10.1093/cercor/bhaf175","DOIUrl":"https://doi.org/10.1093/cercor/bhaf175","url":null,"abstract":"Reinterpretation is one of the primary reappraisal tactics crucial for psychological well-being in emotion regulation (ER). However, it remains unclear how preparatory brain activity influences the temporal dynamics of ER during reinterpretation. Thirty-four young adults involving an adapted ER task, downregulated their negative emotional experiences through reinterpretation. Strategy preparation nearly aligns with strategy use during reactive ER, while preparation precedes use during proactive ER. Behavioral data showed that reactive ER was more effective than proactive ER. Event-related potential (ERP) and decoding results revealed that goal representation engaged attentional resources to maintain regulatory information and suppress irrelevant interference during preparation. This intensive resource allocation may impair the working memory capacity, thereby reducing the regulatory effect in proactive ER. In contrast, reactive ER, unhindered by the preparation stage, preserved sufficient cognitive resources to adaptively re-engage in ER as necessary. Overall, preparation not only influenced the timing of ER but also impeded strategy use. The regulatory effect was determined by the brain activation patterns observed during the regulation stage.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 7","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144717647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

State-space modeling uncovers brain-behavior dynamics of inhibitory control. 状态空间模型揭示了抑制控制的脑-行为动力学。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-07-01 DOI: 10.1093/cercor/bhaf197

Xudong Yun, Weidong Cai, Junjun Fun, Xiaoliang Zhu, Xin Zhao

{"title":"State-space modeling uncovers brain-behavior dynamics of inhibitory control.","authors":"Xudong Yun, Weidong Cai, Junjun Fun, Xiaoliang Zhu, Xin Zhao","doi":"10.1093/cercor/bhaf197","DOIUrl":"https://doi.org/10.1093/cercor/bhaf197","url":null,"abstract":"Inhibitory control, the ability to suppress prepotent but inappropriate action, thought and emotion, plays a crucial role in goal-directed behavior. Neuroimaging studies suggest that this process engages dynamic interactions across canonical brain networks. However, the precise dynamic brain mechanisms underlying inhibitory control and their relationship to individual differences remain poorly understood. To address this gap, we applied a novel state-space model to a large-scale fMRI dataset to investigate latent brain states and their dynamics during a gender-Stroop task. Our study revealed four distinct latent brain states, each characterized by unique functional connectivity patterns. Temporal properties of latent brain states, such as occupancy rates (OR) and mean lifetimes (ML), were significant predictors of the Stroop effect. Specifically, the ML of state S1 showed negative association with the Stroop effect, suggesting that prolonged engagement in this state facilitated inhibitory control. State-specific connectivity patterns also predicted Stroop effects. Compared to S2, S1 showed stronger within- and between-network connectivity. These findings suggest that S1 represents an optimal brain state for resolving conflicts and promoting inhibitory control. Together, our findings shed light on the neural dynamics involved in overcoming sensory-motor conflicts triggered by automatic responses and highlight their potential implications for cognitive interventions.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 7","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validating conceptions on the role of theta and alpha band activity during the management perception-action associations through EEG-tensor decomposition. 通过脑电图张量分解验证θ和α波段活动在管理感知-行动关联中的作用。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-07-01 DOI: 10.1093/cercor/bhaf176

Negin Gholamipourbarogh, Astrid Prochnow, Christian Beste

{"title":"Validating conceptions on the role of theta and alpha band activity during the management perception-action associations through EEG-tensor decomposition.","authors":"Negin Gholamipourbarogh, Astrid Prochnow, Christian Beste","doi":"10.1093/cercor/bhaf176","DOIUrl":"https://doi.org/10.1093/cercor/bhaf176","url":null,"abstract":"Inhibitory control and perception-action integration are fundamental components of executive function, supported by distinct neural mechanisms. This study investigates the roles of theta and alpha oscillations in these processes during a Go/Nogo task, with a sample size of 73 healthy participants, using a novel application of non-negative tensor decomposition. The Non-negative CANDECOMP/PARAFAC algorithm was applied to multi-dimensional EEG data to preserve critical spatial, temporal, and spectral information. Results revealed that mid-frontal theta band activity is strongly associated with the reconfiguration of perception-action associations, particularly during overlapping Nogo trials, where cognitive demands are heightened. Alpha band activity, while less prominent, was also detected, indicating its involvement in top-down inhibitory control during conditions requiring less cognitive reconfiguration. These findings suggest complementary roles for theta and alpha oscillations, with theta playing a dominant role in managing perception-action associations. Tensor decomposition provides an effective means to capture complex neural signatures, offering deeper insights into the oscillatory dynamics that underlie cognitive control processes. This method may improve our understanding of EEG data and validate previous findings on neurophysiological functions in cognitive neuroscience.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 7","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aberrant neural activation during inhibitory control in girls with fragile X syndrome. 脆性X综合征女孩抑制控制过程中的异常神经激活。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-07-01 DOI: 10.1093/cercor/bhaf124

Yuanyuan Gao, Rihui Li, Qianheng Ma, Kristi L Bartholomay, Amy A Lightbody, Allan L Reiss

{"title":"Aberrant neural activation during inhibitory control in girls with fragile X syndrome.","authors":"Yuanyuan Gao, Rihui Li, Qianheng Ma, Kristi L Bartholomay, Amy A Lightbody, Allan L Reiss","doi":"10.1093/cercor/bhaf124","DOIUrl":"10.1093/cercor/bhaf124","url":null,"abstract":"Fragile X syndrome (FXS) is a genetic condition associated with risk for deficits in executive function, especially response inhibition. Under a clinical setting, this study employs a mobile neuroimaging technique, functional near-infrared spectroscopy (fNIRS), to examine differences in inhibition-elicited neural activation between girls with FXS and a control group matched for age, cognitive function, and clinical symptoms. fNIRS data were collected from 42 girls with FXS and 31 controls during a go/nogo task, with valid data available from 35 and 30 respectively. Relative to the control group, girls with FXS showed higher brain activation (NoGo>Go) in the right dorsolateral prefrontal cortex (DLPFC), angular gyrus, precentral gyrus, and left frontal pole, and lower activation in the right ventrolateral prefrontal cortex, frontal pole, precentral cortex, middle temporal cortex, parietal lobe, and left superior temporal cortex. A significant positive correlation was found between DLPFC activation and response inhibition deficits in girls with FXS. Girls with FXS show abnormal neural activation in response to inhibitory stimulus. Aberrant neural activation in DLPFC in girls with FXS is associated with executive function deficits. fNIRS is established to allow participants to engage in a task in relatively more \"real world\" conditions compared to the scanner environment.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 7","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to: Large-scale parameters framework with large convolutional kernel for encoding visual fMRI activity information. 修正：用于编码视觉fMRI活动信息的大卷积核的大规模参数框架。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-07-01 DOI: 10.1093/cercor/bhaf205

引用次数: 0

Subgraph entropy based network approaches for classifying bipolar disorder from resting-state magnetoencephalography. 基于子图熵的静息状态脑磁图双相情感障碍分类方法。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-07-01 DOI: 10.1093/cercor/bhaf182

Qi Sun, Shuming Zhong, Tongtong Li, Ziyang Zhao, Shunkai Lai, Yiliang Zhang, Pan Chen, Ying Wang, Yanbin Jia, Zhijun Yao, Bin Hu

{"title":"Subgraph entropy based network approaches for classifying bipolar disorder from resting-state magnetoencephalography.","authors":"Qi Sun, Shuming Zhong, Tongtong Li, Ziyang Zhao, Shunkai Lai, Yiliang Zhang, Pan Chen, Ying Wang, Yanbin Jia, Zhijun Yao, Bin Hu","doi":"10.1093/cercor/bhaf182","DOIUrl":"https://doi.org/10.1093/cercor/bhaf182","url":null,"abstract":"Currently, bipolar disorder diagnosis is primarily based on clinical interviews. Magnetoencephalography signals reflect changes in the brain's magnetic field induced by neuronal activity. As a result, the combination of magnetoencephalography and network science holds great promise for identifying bipolar disorder biomarkers. However, the existing methods remain limited in capturing the complexity of nodes and their connections within resting-state brain networks, making it difficult to fully reveal underlying pathological mechanisms. In this work, we measured the uncertainty associated with a subgraph, an information-theoretic metric called \"subgraph entropy,\" and used it to identify individuals with bipolar disorder. This method enabled a more accurate characterization of brain network complexity, facilitating the identification of regions closely associated with disease states. The results showed that subgraph entropy features significantly contributed to the classification of bipolar disorder, particularly within the beta frequency band. In addition, two special forms of subgraph entropy, namely node entropy and edge entropy, were examined to identify important brain regions and functional connectivity in bipolar disorder patients across multiple frequency bands. Notably, in the beta frequency band, the method based on edge entropy achieved 0.8462 accuracy, 0.7308 specificity, and 0.9231 sensitivity through leave-one-out cross-validation, effectively distinguishing individuals with bipolar disorder from healthy controls.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 7","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144663872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the sublayer formation process in layer V of the neocortex through two newly identified molecular markers. 通过两个新发现的分子标记探索新皮层V层的亚层形成过程。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-07-01 DOI: 10.1093/cercor/bhaf174

Chunhui Wang, Gaoao Liu, Zefan Jing, Luyao Yin, Xinrun Wang, Lin Hou, Bin Yin, Boqin Qiang, Pengcheng Shu, Xiaozhong Peng

{"title":"Exploring the sublayer formation process in layer V of the neocortex through two newly identified molecular markers.","authors":"Chunhui Wang, Gaoao Liu, Zefan Jing, Luyao Yin, Xinrun Wang, Lin Hou, Bin Yin, Boqin Qiang, Pengcheng Shu, Xiaozhong Peng","doi":"10.1093/cercor/bhaf174","DOIUrl":"https://doi.org/10.1093/cercor/bhaf174","url":null,"abstract":"The precisely organized six-layered architecture of the mammalian neocortex containing diverse types of neurons arises from tightly orchestrated developmental programs. Notably, layer V comprises two principal subtypes of excitatory pyramidal neurons distinguished by their axonal projection targets and stratifies into anatomically distinct sublayers: layer Va and layer Vb. Nevertheless, the mechanisms orchestrating neuronal diversification and their defining molecular markers have yet to be fully elucidated. In this study, we identified two novel molecular markers, Pcp4 (Purkinje cell protein 4, also known as Pep19) and FoxO1 (Forkhead box protein O1), which help define layer Va, characterized by FoxO1+ and Satb2+ neurons; and layer Vb, characterized by Pcp4+ and Ctip2+ neurons, and delineate two functionally discrete subpopulations of layer V projection neurons during late differentiation stages. Meanwhile, our findings were validated in single-cell RNA sequencing (scRNA-seq) data. We then employed two Dicer conditional knockout mouse models and found that microRNA (miRNA) deficiency leads to cortical sublayer disorganization and loss of Pcp4 and FoxO1 expression, demonstrating the essential role of miRNAs in neuronal subtype specification. This study advances our understanding of the molecular mechanisms governing the diversification of layer V neuronal subtypes and their developmental trajectories.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 7","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neural and behavioral entrainment to auditory rhythmic perturbations in persons with cerebellar impairment. 小脑损伤患者听觉节奏扰动的神经和行为夹带。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-07-01 DOI: 10.1093/cercor/bhaf164

Eleonora Baliviera, Mattia Rosso, Bart Moens, Marie Poncelet, Mario Manto, Pierre Cabaraux, Bart Van Wijmeersch, Marc Leman, Peter Feys, Lousin Moumdjian

{"title":"Neural and behavioral entrainment to auditory rhythmic perturbations in persons with cerebellar impairment.","authors":"Eleonora Baliviera, Mattia Rosso, Bart Moens, Marie Poncelet, Mario Manto, Pierre Cabaraux, Bart Van Wijmeersch, Marc Leman, Peter Feys, Lousin Moumdjian","doi":"10.1093/cercor/bhaf164","DOIUrl":"https://doi.org/10.1093/cercor/bhaf164","url":null,"abstract":"The cerebellum plays a key role in temporal processing, as demonstrated by sensorimotor synchronization paradigms. This study extends findings by investigating behavioral and neural adaptation to unpredictable auditory perturbations. Sixteen persons with cerebellar impairment and sixteen healthy controls performed a listening (60 seconds) and a finger-tapping task (465 seconds) to a metronome set at 1.67 Hz: the first 60 seconds were without perturbations, followed by 40 perturbations (±10% period changes). Event-related frequency adjustments (ERFA) were derived from finger-tapping and electroencephalography recordings, yielding 3 event-related frequency adjustments: one behavioral and two neural (perceptual and sensorimotor components). Mean behavioral adaptation to the perturbations was similar in both groups (P < 0.001). Neural tracking was evident in the sensorimotor component but not in the perceptual component in both groups, for both positive (P = 0.005) and negative (P = 0.003) directions. Neural tracking was significantly reduced in persons with cerebellar impairment compared to healthy controls, particularly in response to negative perturbation in the sensorimotor component (P = 0.02). Persons with cerebellar impairment demonstrates spared yet dissociative adaptation with intact behavioral yet hindered neural dynamics. The results suggest parallel yet distinct mechanisms for processing covert and overt responses underlying sensorimotor adaptation. Findings indicate a potential use of spared behavioral adaptation mechanisms in the rehabilitation of persons with cerebellar impairment through rhythm-based interventions.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 7","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The number sense: likely innate, surely not visual. A commentary on "Is there an innate sense of number in the brain?" 数字感：可能是天生的，肯定不是视觉上的。对“大脑中有先天的数字感吗？”

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-07-01 DOI: 10.1093/cercor/bhaf207

Ying Yang, Olivier Collignon

引用次数: 0

Distinct fusiform subregion activity and connectivity in lonely and nonlonely individuals during social information processing. 孤独与非孤独个体在社会信息加工过程中梭状回子区活动与连通性的差异。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-07-01 DOI: 10.1093/cercor/bhaf206

Marcelina Wiśniewska, Aleksandra Piejka, Tomasz Wolak, Łukasz Okruszek

{"title":"Distinct fusiform subregion activity and connectivity in lonely and nonlonely individuals during social information processing.","authors":"Marcelina Wiśniewska, Aleksandra Piejka, Tomasz Wolak, Łukasz Okruszek","doi":"10.1093/cercor/bhaf206","DOIUrl":"https://doi.org/10.1093/cercor/bhaf206","url":null,"abstract":"Loneliness has been recognized as a major public health concern affecting individuals' everyday social functioning. Although hypothesized, the association between chronic loneliness, neural responses, and parasympathetic regulation during social information processing remains underexplored. This study aimed to compare parasympathetic and neural responses to affective social content in well-powered samples of participants with different chronic loneliness levels. In this study, 104 (52 females) healthy young adults were recruited based on their chronic loneliness levels to form groups of lonely and nonlonely individuals. Participants underwent a functional magnetic resonance imaging session in which they passively viewed social and nonsocial images of negative, positive, and neutral valence. Both groups showed similar task-related vagal changes and responses across predefined regions associated with key social brain areas. However, an exploratory whole-brain activity analysis revealed between-group differences in two distinct fusiform face area subregions. Furthermore, the lonely individuals group showed decreased connectivity between one of the fusiform face area subregions and right temporoparietal junction compared to the nonlonely individuals group. These results suggest that trait-like loneliness is associated with distinct processing of social content in fusiform face area subregions, potentially linking loneliness to differences in effective social information integration.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 7","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144759202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0