Cerebral cortex最新文献

Neural dynamics underlying the cue validity effect in target conflict resolution. 目标冲突解决中线索效度效应的神经动力学基础。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-04-01 DOI: 10.1093/cercor/bhaf066

Keyi Duan, Songyun Xie, Xinzhou Xie, Klaus Obermayer, Dalu Zheng, Ying Zhang, Xin Zhang

{"title":"Neural dynamics underlying the cue validity effect in target conflict resolution.","authors":"Keyi Duan, Songyun Xie, Xinzhou Xie, Klaus Obermayer, Dalu Zheng, Ying Zhang, Xin Zhang","doi":"10.1093/cercor/bhaf066","DOIUrl":"https://doi.org/10.1093/cercor/bhaf066","url":null,"abstract":"Cue validity significantly influences attention guidance, either facilitating or hindering the ability for conflict resolution. Previous studies have demonstrated that the validity effect and conflict resolution are associated with better/worse behavioral performance and specific neural activations; however, the underlying neural mechanism of their interaction remains unclear. We hypothesized that the effect of cue validity might sustain specific sequences of neural activities until target occurrence and throughout the subsequent conflict resolution. In this study, we recorded the scalp electroencephalography during the Attention Network Test paradigm to investigate their interactions in neural dynamics. Specifically, we performed a cluster-level channel-time-frequency analysis to explore significant time-frequency neural activity patterns associated with these interactions, in scalp regions of interest determined by a data-driven strategy. Our results revealed a string of significant neural dynamics in the frontal and parietal regions, including initial broad-band (especially the gamma-band) activations and subsequent complex cognitive processes evoked/effected by the invalid cue, that were firstly elicited. Finally, the resolution of conflict was completed by the frontal behavior-related theta-band power reduction. In summary, our findings advanced the understanding of the temporal and spectral sequences of neural dynamics, with the key regions involved in the resolution of conflict after invalid cueing.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain activation patterns reflecting differences in music training: listening by ear vs. reading sheet music for the recognition of contexts and structures in a composition. 反映音乐训练差异的大脑激活模式：通过耳朵听与阅读乐谱来识别作品中的背景和结构。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-04-01 DOI: 10.1093/cercor/bhaf072

Reiya Horisawa, Keita Umejima, Seizo Azuma, Takeaki Miyamae, Ryugo Hayano, Kuniyoshi L Sakai

{"title":"Brain activation patterns reflecting differences in music training: listening by ear vs. reading sheet music for the recognition of contexts and structures in a composition.","authors":"Reiya Horisawa, Keita Umejima, Seizo Azuma, Takeaki Miyamae, Ryugo Hayano, Kuniyoshi L Sakai","doi":"10.1093/cercor/bhaf072","DOIUrl":"10.1093/cercor/bhaf072","url":null,"abstract":"When practicing a new piece of music, what are the neural substrates influenced by short-term training such as listening to recorded sources or reading sheet music? Do those neural mechanisms reflect the effects of long-term training in music? In the present functional magnetic resonance imaging study with intermediate piano players in the middle of acquiring advanced knowledge and skills in music, we compared short-term training of listening to recorded pieces (\"Listen\") and reading sheet music (\"Read\"). Participants were \"Multi-\" and \"Mono-instrumentalist\" groups according to whether they played multiple instruments or only the piano. We used an error-detection task with music stimuli including structural errors made by swapping 2 phrases within a composition, thereby focusing on contextual comprehension of musical phrases. Overall performances were significantly better under Listen than under Read, and significantly better in Multi than in Mono. Moreover, we observed left-lateralized frontal activations under Listen for Multi, whereas bilateral temporo-frontal regions were activated under Read for both groups. Focusing on individual differences under Read, we found a positive correlation between the frontal activations and the accuracy rates for Mono. Overall, our results elucidate how the neural substrates of judgments on structures and context in music are influenced by both long-term and short-term training.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11959692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Information transfer and recovery for the sense of touch. 触觉的信息传递和恢复。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-04-01 DOI: 10.1093/cercor/bhaf073

Chao Huang, Bernhard Englitz, Andrey Reznik, Fleur Zeldenrust, Tansu Celikel

引用次数: 0

Neural correlates of how egoistic, altruistic, and mixed motivations modulate the influence of self-deception on deceptive behavior. 利己主义、利他主义和混合动机如何调节自我欺骗对欺骗行为的影响的神经关联。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-04-01 DOI: 10.1093/cercor/bhaf077

Zijun Huang, Bowei Zhong, Tengji Yang, Wei Fan

{"title":"Neural correlates of how egoistic, altruistic, and mixed motivations modulate the influence of self-deception on deceptive behavior.","authors":"Zijun Huang, Bowei Zhong, Tengji Yang, Wei Fan","doi":"10.1093/cercor/bhaf077","DOIUrl":"10.1093/cercor/bhaf077","url":null,"abstract":"Using event-related potentials, this study investigated the interplay between self-deception and varying motivations in influencing deceptive behavior. Participants in either the self-deception or nonself-deception condition were instructed to make deceptive decisions under different motivational contexts. Behavioral responses and neural activity were recorded throughout the decision-making process. Behaviorally, there were no significant differences in deception proportions between the self-deception and nonself-deception conditions under egoistic or mixed motivations. However, under altruistic motivation, participants in the self-deception condition engaged in more deceptive behavior compared to those in the nonself-deception condition. Event-related potential results revealed no significant differences in P2 and N2 amplitudes between the self-deception and nonself-deception conditions under egoistic or mixed motivations. However, under altruistic motivation, the self-deception condition was associated with reduced P2 amplitudes and more negative N2 amplitudes relative to the nonself-deception condition. Additionally, no significant interaction in P3 amplitudes was found between self-deception and different motivations. These findings suggest that the effect of self-deception on deceptive behavior is modulated by different motivations. Specifically, egoistic or mixed motivations might be associated with a self-serving tendency in deceptive behavior, while altruistic motivation appeared to enhance deceptive behavior in the self-deception condition, potentially to foster a prosocial image.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain connectivity changes in response to cortical electrical stimulation in blind neuroprosthesis users. 盲人神经假体使用者在皮质电刺激下的脑连通性改变。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-04-01 DOI: 10.1093/cercor/bhaf075

Fernando Daniel Farfán, Leili Soo, Fabrizio Grani, María Dolores Grima-Murcia, Eduardo Fernández

{"title":"Brain connectivity changes in response to cortical electrical stimulation in blind neuroprosthesis users.","authors":"Fernando Daniel Farfán, Leili Soo, Fabrizio Grani, María Dolores Grima-Murcia, Eduardo Fernández","doi":"10.1093/cercor/bhaf075","DOIUrl":"10.1093/cercor/bhaf075","url":null,"abstract":"The success of visual neuroprostheses in long-term blind individuals depends not only on the prosthetic technology but also on the brain's ability to readjust its multimodal sensory processing circuits. This study investigates longitudinal changes in resting-state cortical connectivity in two blind subjects implanted with an intracortical microelectrode array (10 × 10 Utah Electrode Array) in the visual cortex for 6 months. During this period, daily microstimulation sessions elicited phosphene perception, and periodic electroencephalographic recordings in the resting state were conducted. Cortical connectivity was quantified using spectral coherence across 64 electroencephalographic channels. Results revealed significant changes in connectivity patterns pre- and post-implantation, with linear trends observed during the implantation period. These trends varied between subjects: User 1 exhibited changes in the 7 to 13 Hz band, while user 2 showed changes in the 15 to 30 Hz band. This study highlights the brain's adaptive capacity in response to sensory restoration and provides insights into optimizing neuroplasticity for improved outcomes in neuroprosthetic interventions.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing creativity with covert neurofeedback: causal evidence for default-executive network coupling in creative thinking. 用隐蔽神经反馈增强创造力：创造性思维中默认-执行网络耦合的因果证据。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-04-01 DOI: 10.1093/cercor/bhaf065

Simone A Luchini, Xinbing Zhang, Ryan T White, Michael Lührs, Michal Ramot, Roger E Beaty

{"title":"Enhancing creativity with covert neurofeedback: causal evidence for default-executive network coupling in creative thinking.","authors":"Simone A Luchini, Xinbing Zhang, Ryan T White, Michael Lührs, Michal Ramot, Roger E Beaty","doi":"10.1093/cercor/bhaf065","DOIUrl":"10.1093/cercor/bhaf065","url":null,"abstract":"Creativity neuroscience has consistently reported increased functional connectivity between the default mode network and the executive control network supports creative cognition, potentially reflecting coordination of generative and evaluative cognitive processes. However, evidence has been purely correlational-no causal demonstrations show that default mode network-executive control network interaction specifically drives creative performance. We sought causal evidence for default mode network-executive control network coupling in creative thinking using functional near-infrared spectroscopy-brain connectivity neurofeedback, which can endogenously modify functional connectivity through reinforcement learning. Importantly, we employed covert neurofeedback, where participants were unaware of the specific brain activity being trained, allowing for unbiased evaluation of cognitive and neural impacts. In a default-executive neurofeedback condition (n = 15), we entrained coupling between the medial prefrontal cortex and the dorsolateral prefrontal cortex, hubs of the default mode network and executive control network, respectively. We compared this with a default-motor condition (n = 15), entraining coupling between the medial prefrontal cortex and the supplementary motor area. Approximately 24 h later, default-executive neurofeedback led to increased coupling between the default mode network and the executive control network during a creative thinking task (generating creative object uses), extending to broader default mode network regions. Behaviorally, we observed a double dissociation: The default-executive condition increased idea originality, while the default-motor condition improved go/no-go reaction times. We thus provide the first evidence that default mode network-executive control network coupling causally enhances creative performance.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the neural mechanisms linking healthy aging and cognitive maintenance: insights from Mendelian randomization and mediation analyses. 探索健康衰老和认知维持之间的神经机制：来自孟德尔随机化和中介分析的见解。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-03-06 DOI: 10.1093/cercor/bhaf006

Tianyuyi Feng, Weizhong Xiao, Yunfei Li, Xiaohu Zhao

{"title":"Exploring the neural mechanisms linking healthy aging and cognitive maintenance: insights from Mendelian randomization and mediation analyses.","authors":"Tianyuyi Feng, Weizhong Xiao, Yunfei Li, Xiaohu Zhao","doi":"10.1093/cercor/bhaf006","DOIUrl":"https://doi.org/10.1093/cercor/bhaf006","url":null,"abstract":"As global population ages, maintaining cognitive health in elderly is crucial. Previous studies suggest a positive link between healthy aging and cognition, but the neural mechanisms remain unclear. This study used genome-wide association studydata to investigate neural mechanisms between healthy aging and cognition. We employed 2-sample Mendelian randomization to evaluate causal relationship between healthy aging (indexed by a multivariate genetic predictor, mvAge) and 6 cognitive measurements. We then used a 2-step Mendelian randomization approach and mediation analysis to identify brain imaging-derived phenotypes potentially mediating this relationship. Mendelian randomization analysis indicated that healthy aging had a positive causal relationship with various cognitive functions (common executive function, intelligence, cognitive performance, and fluid intelligence score). Two-step Mendelian randomization analysis identified 27 brain imaging-derived phenotypes having robust causal relationships with healthy aging and various cognitive measurements. Mediation analysis suggested that volume of subcallosal cortex might mediate effects of healthy aging on all 4 cognitive functions. Volume of cerebellum's VIIb could mediate effects on common executive functions, while fractional anisotropy in the anterior thalamic radiation might mediate effects on intelligence and cognitive performance. These findings suggest that specific brain regions may play a potential mediating role in the relationship between healthy aging and cognitive maintenance.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Normative modeling of brain morphometry in self-limited epilepsy with centrotemporal spikes. 自限性癫痫伴中央颞叶尖峰的脑形态计量学规范建模。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-03-06 DOI: 10.1093/cercor/bhaf064

Siqi Yang, Wei Liao, Yimin Zhou, Chengzong Peng, Juan Wang, Zhiqiang Zhang

{"title":"Normative modeling of brain morphometry in self-limited epilepsy with centrotemporal spikes.","authors":"Siqi Yang, Wei Liao, Yimin Zhou, Chengzong Peng, Juan Wang, Zhiqiang Zhang","doi":"10.1093/cercor/bhaf064","DOIUrl":"https://doi.org/10.1093/cercor/bhaf064","url":null,"abstract":"Self-limited epilepsy with centrotemporal spikes is the most common pediatric epilepsy, characterized by an age-dependent onset that typically arises during childhood brain development and is followed by remission at puberty. However, the heterogeneity in children's brain development at the individual level complicates the challenge of personalized treatment. Our goal is to quantify individual deviations from the normative range of brain morphometric variation in children with Self-limited epilepsy with centrotemporal spikes and to assess their associations with clinical manifestations and cognitive functions. We have developed sex-specific normative models on regional subcortical volume, cortical thickness, and surface area data from 457 healthy children sourced from two datasets. These models were then utilized to map the brain morphometric deviations of children with Self-limited epilepsy with centrotemporal spikes (n = 187) and sex- and age-matched healthy controls (n = 108) from another dataset. In the Self-limited epilepsy with centrotemporal spikes group, children exhibited a higher proportion of regions with infra-normal deviations in subcortical volumes, the number of regions with normative deviations correlated with disease duration, seizure frequency, and Raven's total score. Our findings suggest that a few extreme distributions of heterogeneous brain morphometric deviations are present in a minority of individuals, emphasizing the need to monitor brain abnormalities throughout the course of the disease.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The hippocampus-IPL connectivity links to ADHD traits through sensory processing sensitivity. 海马体- ipl连接通过感觉处理敏感性与ADHD特征联系起来。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-03-06 DOI: 10.1093/cercor/bhaf063

Liyu Zhou, Ting Xu, Tingyong Feng

{"title":"The hippocampus-IPL connectivity links to ADHD traits through sensory processing sensitivity.","authors":"Liyu Zhou, Ting Xu, Tingyong Feng","doi":"10.1093/cercor/bhaf063","DOIUrl":"https://doi.org/10.1093/cercor/bhaf063","url":null,"abstract":"Accumulating evidence suggests that individuals with high sensory processing sensitivity often experience sensory overload and have difficulty sustaining attention, which can particularly resemble attention deficit symptoms of attention-deficit/hyperactivity disorder. However, due to the lack of understanding about the potential neural pathways involved in those processes, a comprehensive view of how sensory processing sensitivity and attention deficit are related is generally limited. Here, we quantified the sensory processing sensitivity and attention deficit using the Highly Sensitive Person Scale and the Adult Attention-deficit/Hyperactivity Disorder Self-Report Scale, respectively, to investigate the association between sensory processing sensitivity and attention deficit and further identify the corresponding neural substrates via the use of resting-state functional Magnetic Resonance Imaging (fMRI) analyses. On the behavioral level, the results indicated a significantly positive correlation between sensory processing sensitivity and attention deficit traits, while on the neural level, the sensory processing sensitivity score was positively correlated with functional connectivity between the rostral hippocampus and inferior parietal lobule, which is the core regions of the attention network. Mediation analysis revealed that hippocampus-Inferior Parietal Lobule (IPL) connectivity can further influence attention deficit through a mediating role of sensory processing sensitivity. Overall, these findings suggest that enhanced functional coupling between the hippocampus and attention network regions may heighten sensitivity to environmental stimuli, leading to increased distractibility and potentially contributing to attention deficit.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decoding the impact of negative physical self-perception on inhibitory control ability from theta and beta rhythms. 从θ和β节律解读消极身体自我知觉对抑制控制能力的影响。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-03-06 DOI: 10.1093/cercor/bhaf056

Junwei Lian, Jiaqi Guo, Xu Dai, Xia Deng, Yong Liu, Jia Zhao, Xu Lei

{"title":"Decoding the impact of negative physical self-perception on inhibitory control ability from theta and beta rhythms.","authors":"Junwei Lian, Jiaqi Guo, Xu Dai, Xia Deng, Yong Liu, Jia Zhao, Xu Lei","doi":"10.1093/cercor/bhaf056","DOIUrl":"https://doi.org/10.1093/cercor/bhaf056","url":null,"abstract":"Previous studies have found inhibitory control differences between obese individuals and those of normal weight. However, some normal-weight individuals with high negative physical self-perception on the fatness subscale show restrictive eating behaviors and attentional bias toward high-calorie food, potentially influencing these differences. We collected behavioral and electroencephalography data using a novel inhibitory control task. Results showed that individuals with high negative physical self-perception on the fatness subscale exhibited significantly greater restraint eating behavior compared to controls. Both theta and beta power differed between groups, with higher theta power in the high negative physical self-perception on the fatness subscale group than in the obese group and more negative beta power in the high negative physical self-perception on the fatness subscale group compared to both other groups. Theta power was greater in no-go than go conditions, while beta power was more negative in response to high-calorie versus low-calorie food stimuli. Importantly, theta power successfully decoded go/no-go conditions across all groups using multivariate pattern analysis, while beta power distinguished these conditions only in the negative physical self-perception on the fatness subscale and control groups. These findings suggest that theta and beta power, along with multivariate pattern analysis, can reliably distinguish inhibitory control ability among the three groups, highlighting the importance of considering negative physical self-perception on the fatness subscale when assessing inhibitory control differences between normal-weight and obese individuals.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0