Cerebral cortex最新文献_第7页

Monitoring of nonspatial information within working memory in the common marmoset (Callithrix jacchus). 普通狨猴（Callithrix jacchus）工作记忆中对非空间信息的监测。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2024-11-05 DOI: 10.1093/cercor/bhae444

Veronika Zlatkina, Stephen Frey, Michael Petrides

引用次数: 0

Convolutional neural networks uncover the dynamics of human visual memory representations over time. 卷积神经网络揭示了人类视觉记忆表征随时间变化的动态过程。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2024-11-05 DOI: 10.1093/cercor/bhae447

Eden Zohar, Stas Kozak, Dekel Abeles, Moni Shahar, Nitzan Censor

{"title":"Convolutional neural networks uncover the dynamics of human visual memory representations over time.","authors":"Eden Zohar, Stas Kozak, Dekel Abeles, Moni Shahar, Nitzan Censor","doi":"10.1093/cercor/bhae447","DOIUrl":"https://doi.org/10.1093/cercor/bhae447","url":null,"abstract":"The ability to accurately retrieve visual details of past events is a fundamental cognitive function relevant for daily life. While a visual stimulus contains an abundance of information, only some of it is later encoded into long-term memory representations. However, an ongoing challenge has been to isolate memory representations that integrate various visual features and uncover their dynamics over time. To address this question, we leveraged a novel combination of empirical and computational frameworks based on the hierarchal structure of convolutional neural networks and their correspondence to human visual processing. This enabled to reveal the contribution of different levels of visual representations to memory strength and their dynamics over time. Visual memory strength was measured with distractors selected based on their shared similarity to the target memory along low or high layers of the convolutional neural network hierarchy. The results show that visual working memory relies similarly on low and high-level visual representations. However, already after a few minutes and on to the next day, visual memory relies more strongly on high-level visual representations. These findings suggest that visual representations transform from a distributed to a stronger high-level conceptual representation, providing novel insights into the dynamics of visual memory over time.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"34 11","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Local and interareal alpha and low-beta band oscillation dynamics underlie the bilateral field advantage in visual working memory. 局部和区域间阿尔法和低贝塔波段振荡动力学是视觉工作记忆双侧场优势的基础。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2024-11-05 DOI: 10.1093/cercor/bhae448

Judith Sattelberger, Hamed Haque, Joonas J Juvonen, Felix Siebenhühner, Jaakko Matias Palva, Satu Palva

{"title":"Local and interareal alpha and low-beta band oscillation dynamics underlie the bilateral field advantage in visual working memory.","authors":"Judith Sattelberger, Hamed Haque, Joonas J Juvonen, Felix Siebenhühner, Jaakko Matias Palva, Satu Palva","doi":"10.1093/cercor/bhae448","DOIUrl":"10.1093/cercor/bhae448","url":null,"abstract":"Visual working memory has a limited maximum capacity, which can be larger if stimuli are presented bilaterally vs. unilaterally. However, the neuronal mechanisms underlying this bilateral field advantage are not known. Visual working memory capacity is predicted by oscillatory delay-period activity, specifically, by a decrease in alpha (8 to 12 Hz) band amplitudes in posterior brain regions reflecting attentional deployment and related shifts in excitation, as well as a concurrent increase of prefrontal oscillation amplitudes and interareal synchronization in multiple frequencies reflecting active maintenance of information. Here, we asked whether posterior alpha suppression or prefrontal oscillation enhancement explains the bilateral field advantage. We recorded brain activity with high-density electroencephalography, while subjects (n = 26, 14 males) performed a visual working memory task with uni- and bilateral visual stimuli. The bilateral field advantage was associated with early suppression of low-alpha (6 to 10 Hz) and alpha-beta (10 to 17 Hz) band amplitudes, and a subsequent alpha-beta amplitude increase, which, along with a concurrent load-dependent interareal synchronization in the high-alpha band (10 to 15 Hz), correlated with hit rates and reaction times and thus predicted higher maximum capacities in bilateral than unilateral visual working memory. These results demonstrate that the electrophysiological basis of the bilateral field advantage in visual working memory is both in the changes in attentional deployment and enhanced interareal integration.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"34 11","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Online transcranial magnetic stimulation reveals dynamic interactions between language control and processing in bilingual language production. 在线经颅磁刺激揭示了双语语言生成过程中语言控制与语言处理之间的动态互动。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2024-11-05 DOI: 10.1093/cercor/bhae452

Junjie Wu, Yannan Ji, Chuyao Cai, Xinping Pu, Qiping Wang, Guoli Yan, Qiang Wang, Xin Wang

{"title":"Online transcranial magnetic stimulation reveals dynamic interactions between language control and processing in bilingual language production.","authors":"Junjie Wu, Yannan Ji, Chuyao Cai, Xinping Pu, Qiping Wang, Guoli Yan, Qiang Wang, Xin Wang","doi":"10.1093/cercor/bhae452","DOIUrl":"10.1093/cercor/bhae452","url":null,"abstract":"Language production in bilinguals relies on the collaborative interaction between two neural systems: the language control system (e.g. the right inferior frontal gyrus) and the language processing system (e.g. the left superior temporal gyrus). However, the causal mapping between these brain systems and their cognitive functions, as well as the temporal dynamics between these two systems during bilingual language production, remain unclear. To investigate this, our study applied online transcranial magnetic stimulation to the right inferior frontal gyrus and left superior temporal gyrus in Chinese-English bilinguals performing a language-switching task. Transcranial magnetic stimulation was administered within seven 100 ms time windows (TW1 to TW7) following the picture onset. We observed time window-specific enhancements of language control, as shown by a significant reduction in switching costs upon the stimulations on both sites relative to the sham stimulation: specifically, the right inferior frontal gyrus at TW1, TW2, TW4, and TW5 and the left superior temporal gyrus at TW2 and TW5. These findings indicate a double-strike top-down control mechanism underpinned by the pathway from the right inferior frontal gyrus to the right inferior frontal gyrus, potentially during both stages during production: the language task schema and the lemma selection. Our study provides the first evidence of the dynamic interactions between language control and processing systems causally underpinning bilingual language production.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"34 11","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11602258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142738520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiac cycle modulates alpha and beta suppression during motor imagery. 心动周期调节运动想象过程中的α和β抑制。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2024-11-05 DOI: 10.1093/cercor/bhae442

Giuseppe Lai, David Landi, Carmen Vidaurre, Joydeep Bhattacharya, Maria Herrojo Ruiz

{"title":"Cardiac cycle modulates alpha and beta suppression during motor imagery.","authors":"Giuseppe Lai, David Landi, Carmen Vidaurre, Joydeep Bhattacharya, Maria Herrojo Ruiz","doi":"10.1093/cercor/bhae442","DOIUrl":"10.1093/cercor/bhae442","url":null,"abstract":"Previous interoception research has demonstrated that sensory processing is reduced during cardiac systole, an effect associated with diminished cortical excitability, possibly due to heightened baroreceptor activity. This study aims to determine how phases of the cardiac cycle-systole and diastole-modulate neural sensorimotor activity during motor imagery (MI) and motor execution (ME). We hypothesised that MI performance, indexed by enhanced suppression of contralateral sensorimotor alpha (8-13 Hz) and beta (14-30 Hz) activity, would be modulated by the cardiac phases, with improved performance during diastole due to enhanced sensory processing of movement cues. Additionally, we investigated whether movement cues during systole or diastole enhance muscle activity. To test these hypotheses, 29 participants were instructed to perform or imagine thumb abductions, while we recorded their electroencephalography, electrocardiogram, and electromyogram (EMG) activity. We show that imaginary movements instructed during diastole lead to more pronounced suppression of alpha and beta activity in contralateral sensorimotor cortices, with no significant cardiac timing effects observed during ME as confirmed by circular statistics. Additionally, diastole was associated with significantly increased EMG on the side of actual and, to a lesser degree, imagined movements. Our study identifies optimal cardiac phases for MI performance, suggesting potential pathways to enhance MI-based assistive technologies.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"34 11","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584698/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurophysiological characteristics of reward processing in individuals at different levels of gaming. 不同游戏水平的个体奖励处理的神经生理学特征。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2024-11-05 DOI: 10.1093/cercor/bhae436

Yanjie Peng, DanTong Wu, Mingyuan Tian, Yanyin Zhou, Xiaohong Peng, Zhenlei Peng, Ke Gong, Kezhi Liu, Jing Chen, Wei Lei

{"title":"Neurophysiological characteristics of reward processing in individuals at different levels of gaming.","authors":"Yanjie Peng, DanTong Wu, Mingyuan Tian, Yanyin Zhou, Xiaohong Peng, Zhenlei Peng, Ke Gong, Kezhi Liu, Jing Chen, Wei Lei","doi":"10.1093/cercor/bhae436","DOIUrl":"https://doi.org/10.1093/cercor/bhae436","url":null,"abstract":"Altered reward processing has been repeatedly reported in Internet gaming disorder (IGD). However, it remains unclear whether these changes are linked to the severity of addictive symptoms or the extent of gaming experience. This study examined the neurophysiological responses regarding reward anticipation and consummation in individuals at different levels of gaming (including 22 casual gamers, 31 regular gamers, and 27 individuals with IGD) through a monetary incentive delay task. Three event-related potential components during reward anticipation-cue-related P300 (Cue-P3), contingent negative variation, and stimulus-preceding negativity (SPN)-and two during reward consummation-feedback-related negativity and feedback-related P300 (FB-P3)-were measured. We found that IGD individuals exhibited greater Cue-P3 but lower SPN amplitude compared to casual gamers, while regular gamers fell between the two without significant differences. Regressions indicated that more extensive gaming experience, rather than the severity of the symptoms, primarily contributed to the increased Cue-P3 in IGD. No group differences were found during reward consummation. Our results highlight disrupted reward anticipation processing in IGD, characterized by increased attention bias toward reward cues (Cue-P3) but diminished cognitive resources for reward anticipation (SPN) and emphasize the role of gaming experience in increased attention bias in IGD.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"34 11","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain functional gradients are related to cortical folding gradient. 大脑功能梯度与皮层折叠梯度有关。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2024-11-05 DOI: 10.1093/cercor/bhae453

Zhibin He, Tuo Zhang, Qiyu Wang, Songyao Zhang, Guannan Cao, Tianming Liu, Shijie Zhao, Xi Jiang, Lei Guo, Yixuan Yuan, Junwei Han

{"title":"Brain functional gradients are related to cortical folding gradient.","authors":"Zhibin He, Tuo Zhang, Qiyu Wang, Songyao Zhang, Guannan Cao, Tianming Liu, Shijie Zhao, Xi Jiang, Lei Guo, Yixuan Yuan, Junwei Han","doi":"10.1093/cercor/bhae453","DOIUrl":"https://doi.org/10.1093/cercor/bhae453","url":null,"abstract":"Cortical folding is closely linked to brain functions, with gyri acting more like local functional \"hubs\" to integrate information than sulci do. However, understanding how anatomical constraints relate to complex functions remains fragmented. One possible reason is that the relationship is estimated on brain mosaics divided by brain functions and cortical folding patterns. The boundaries of these hypothetical hard-segmented mosaics could be subject to the selection of functional/morphological features and as well as the thresholds. In contrast, functional gradient and folding gradient could provide a more feasible and unitless platform to mitigate the uncertainty introduced by boundary definition. Based on the MRI datasets, we used cortical surface curvature as the folding gradient and related it to the functional connectivity transition gradient. We found that, at the local scale, the functional gradient exhibits different function transition patterns between convex/concave cortices, with positive/negative curvatures, respectively. At the global scale, a cortex with more positive curvature could provide more function transition efficiency and play a more dominant role in more abstractive functional networks. These results reveal a novel relation between cortical morphology and brain functions, providing new clues to how anatomical constraint is related to the rise of an efficient brain function architecture.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"34 11","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142680886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuronal fate resulting from indirect neurogenesis in the mouse neocortex. 小鼠新皮层中间接神经发生导致的神经元命运

IF 2.9 2区医学

Cerebral cortex Pub Date : 2024-11-05 DOI: 10.1093/cercor/bhae439

Yumiko Hatanaka, Kentaro Yamada, Tomoki Eritate, Yasuo Kawaguchi, Tatsumi Hirata

{"title":"Neuronal fate resulting from indirect neurogenesis in the mouse neocortex.","authors":"Yumiko Hatanaka, Kentaro Yamada, Tomoki Eritate, Yasuo Kawaguchi, Tatsumi Hirata","doi":"10.1093/cercor/bhae439","DOIUrl":"https://doi.org/10.1093/cercor/bhae439","url":null,"abstract":"Excitatory cortical neurons originate from cortical radial glial cells (RGCs). Initially, these neurons were thought to derive directly from RGCs (direct neurogenesis) and be distributed in an inside-out fashion. However, the discovery of indirect neurogenesis, whereby intermediate neuronal progenitors (INPs) generate neurons, challenged this view. To investigate the integration of neurons via these two modes, we developed a method to identify INP progeny and analyze their fate using transgenic mice expressing tamoxifen-inducible Cre recombinase under the neurogenin-2 promoter, alongside thymidine analog incorporation. Their fate was further analyzed using mosaic analysis with double markers in mice. Indirect neurogenesis was prominent during early neurogenesis, generating neuron types that would emerge slightly later than those produced via direct neurogenesis. Despite the timing difference, both neurogenic modes produced fundamentally similar neuron types, as evidenced by marker expression and cortical-depth location. Furthermore, INPs generated pairs of similar phenotype neurons. These findings suggest that indirect neurogenesis, like direct neurogenesis, generates neuron types in a temporally ordered sequence and increases the number of similar neuron types, particularly in deep layers. Thus, both neurogenic modes cooperatively generate a diverse array of neuron types in a similar order, and their progeny populate together to form a coherent cortical structure.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"34 11","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain-clinical pattern alterations after treatment in schizophrenia. 精神分裂症治疗后的大脑临床模式改变。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2024-11-05 DOI: 10.1093/cercor/bhae461

Rixing Jing, Qiandong Wang, Guozhong Liu, Jie Shi, Yong Fan, Lin Lu, Xiao Lin, Peng Li

{"title":"Brain-clinical pattern alterations after treatment in schizophrenia.","authors":"Rixing Jing, Qiandong Wang, Guozhong Liu, Jie Shi, Yong Fan, Lin Lu, Xiao Lin, Peng Li","doi":"10.1093/cercor/bhae461","DOIUrl":"https://doi.org/10.1093/cercor/bhae461","url":null,"abstract":"Discovering meaningful brain-clinical patterns would be a significant advancement for elucidating the pathophysiology underlying schizophrenia. In the present study, we analyzed associations between functional brain characters (average functional connectivity strength and its fluctuations) and clinical features (age onset, illness duration, and positive, negative, disorganized, excited, and depressed) using partial least squares. Also, we analyzed the brain-clinical relationship changes after 6-wk of treatment. At baseline, 2 identified latent brain-clinical dimensions collectively accounted for 33.2% of the covariance between clinical data and brain function. The illness onset age and duration significantly contributed to all latent dimensions. The disorganized symptoms contributed to the first latent variable, while the positive and depressed symptoms notably negatively contributed to the second variable. The average functional connectivity strength of first latent variable could positively predict the treatment effect, especially in the positive, negative, excited, and overall symptoms. No significant correlation between average functional connectivity strength and treatment effect was obtained in second latent variable. We also found that functional connectivity and its fluctuations altered after treatment, with similar patterns of brain characteristic alterations across the 2 latent variables. By simultaneously taking into account both clinical manifestations and brain abnormalities, the present results open new avenues for predicting treatment responses in schizophrenia.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"34 11","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142738515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neural representations of phonological information in bilingual language production. 双语语言生产中语音信息的神经表征

IF 2.9 2区医学

Cerebral cortex Pub Date : 2024-11-05 DOI: 10.1093/cercor/bhae451

Xiaoyu Liu, Xiaoyan Wu, Yuan Feng, Jingyu Yang, Nannan Gu, Leilei Mei

{"title":"Neural representations of phonological information in bilingual language production.","authors":"Xiaoyu Liu, Xiaoyan Wu, Yuan Feng, Jingyu Yang, Nannan Gu, Leilei Mei","doi":"10.1093/cercor/bhae451","DOIUrl":"https://doi.org/10.1093/cercor/bhae451","url":null,"abstract":"Previous research has explored the neural mechanisms of bilinguals' language production, but most studies focused on neural mechanisms of cognitive control during language production. Therefore, it is unclear which brain regions represent lexical information (especially phonological information) during production and how they are affected by language context. To address those questions, we used representational similarity analysis to explore neural representations of phonological information in native (L1) and second languages (L2) in the single- and mixed-language contexts, respectively. Results showed that Chinese-English bilinguals behaviorally performed worse and exhibited more activations in brain regions associated with language processing and cognitive control in the mixed-language context relative to the single-language context. Further representational similarity analysis revealed that phonological representations of L1 were detected in the left pars opercularis, middle frontal gyrus, and anterior supramarginal gyrus, while phonological representations of L2 were detected in the bilateral occipitotemporal cortex regardless of the target language. More interestingly, robust phonological representations of L1 were observed in brain areas related to phonological processing during L2 production regardless of language context. These results provide direct neuroimaging evidence for the nonselective processing hypothesis and highlight the superiority of phonological representations in the dominant language during bilingual language production.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"34 11","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0