Cerebral cortex最新文献_第6页

Finger and nerve selectivity of an early somatic-motor interaction: a magnetoencephalogram study. 早期躯体-运动相互作用的手指和神经选择性：脑磁图研究。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-05-01 DOI: 10.1093/cercor/bhaf113

Tetsuo Kida, Emi Tanaka, Koji Inui

{"title":"Finger and nerve selectivity of an early somatic-motor interaction: a magnetoencephalogram study.","authors":"Tetsuo Kida, Emi Tanaka, Koji Inui","doi":"10.1093/cercor/bhaf113","DOIUrl":"https://doi.org/10.1093/cercor/bhaf113","url":null,"abstract":"Voluntary movements of individual or multiple body parts selectively modulate cortical responsiveness to sensory inputs depending on the task requirement. It remains unclear whether this selectivity of the somatic-motor interaction in the cerebral cortex is complete or gradient along the surface of the body part and varies with task characteristics. We herein used magnetoencephalograms to investigate the selectivity of the somatic-motor interactive modulation of somatosensory evoked cortical responses during self-paced movements of individual fingers (digits 1 to 5) or dynamic self-paced tapping or static pinching movements of two fingers (digits 1 and 2). The source strength of the cortical response at 35 ms post-stimulus contralateral to a stimulation, M35c, selectively decreased when the finger innervated by the stimulated nerve was individually moved. Furthermore, dynamic tapping and static pinching movements of two fingers exerted different effects on the strength of M35c. Therefore, the present study demonstrates the involvement of finger and nerve specificity in the somatic-motor functional interaction at the early cortical stage and its task-dependent flexibility.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of working memory training on brain network integration and neurotransmitter systems: a resting-state fMRI. 工作记忆训练对大脑网络整合和神经递质系统的影响：静息状态功能磁共振成像。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-05-01 DOI: 10.1093/cercor/bhaf081

Chaozong Ma, Yijun Li, Yuntao Gao, Xinxin Lin, Yilin Hou, Wei He, Yuanqiang Zhu, Jun Jiang, Yuanjun Xie, Peng Fang

{"title":"Impact of working memory training on brain network integration and neurotransmitter systems: a resting-state fMRI.","authors":"Chaozong Ma, Yijun Li, Yuntao Gao, Xinxin Lin, Yilin Hou, Wei He, Yuanqiang Zhu, Jun Jiang, Yuanjun Xie, Peng Fang","doi":"10.1093/cercor/bhaf081","DOIUrl":"10.1093/cercor/bhaf081","url":null,"abstract":"Working memory training (WMT) has been demonstrated to enhance cognitive performance, yet the underlying neural mechanisms remain insufficiently understood. Brain network connectivity, particularly as measured by the participation coefficient (PC), offers a valuable framework for elucidating these neural changes. This study investigated the effects of WMT on brain network connectivity, utilizing PC as a primary assessment of network integration and segregation. The relationship between WMT-induced changes in PC and the density of specific neurotransmitter receptors was examined. Seventy-six healthy participants were randomly assigned to either a WMT group or a control group. After 8 wks of training, the WMT group exhibited significant cognitive improvements, especially in near and far transfer tasks. These behavioral improvements were accompanied by specific changes in brain connectivity, including a reduction in PC within the sensorimotor network and node-specific alterations in the left prefrontal cortex, temporo-occipital-parietal junction, and parietal operculum. Moreover, changes in PC were significantly correlated with the density of dopamine D2 receptors, mu-opioid receptors, and metabotropic glutamate receptor 5. These findings enhance our understanding of how WMT influences cognitive function and brain network connectivity, highlighting the potential for targeting specific networks and neurotransmitter systems in cognitive training interventions.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining the role of phonological and semantic mechanisms during morphological processing of sentences in 7-year-old children. 研究语音和语义机制在7岁儿童句子形态加工中的作用。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-05-01 DOI: 10.1093/cercor/bhaf115

Marjolein Mues, Avantika Mathur, James Booth

{"title":"Examining the role of phonological and semantic mechanisms during morphological processing of sentences in 7-year-old children.","authors":"Marjolein Mues, Avantika Mathur, James Booth","doi":"10.1093/cercor/bhaf115","DOIUrl":"10.1093/cercor/bhaf115","url":null,"abstract":"Morphology refers to the smallest difference in sound that makes a difference in meaning, such as walk versus walked. Morphological skill is a key linguistic feature that impacts language and literacy outcomes, but its neural underpinnings have mostly been examined at the word level. We examined if phonological and semantic mechanisms play a role during morphological processing in sentences in 7-year-old children using functional MRI. Using a novel functional localizer approach that correlates brain activation during sound and meaning in-scanner tasks with standardized scores for phonology and semantics, we show that morphological processing is especially reliant on phonological mechanisms given significant activation in the left dorsal inferior frontal gyrus and left posterior superior temporal gyrus. Semantic mechanisms were engaged to a lesser degree in the left ventral inferior frontal gyrus. Exploratory whole-brain analyses revealed a brain-behavior correlation in the cerebellum showing that greater activation during morphological processing was related to lower language abilities. Our results suggest that processing morphological structures in sentences relies mostly on phonemic segmentation, and that those with lower language may compensate for their lower phonological skill by engaging the cerebellum to amplify and refine those phonemic representations to aid in segmentation when listening to sentences.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12075772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infant dominant rhythm desynchronization to faces and objects. 婴儿主导节奏与面部和物体不同步。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-05-01 DOI: 10.1093/cercor/bhaf087

Mina Elhamiasl, Maeve R Boylan, Ryan Barry-Anwar, Zoe Pestana, Andreas Keil, Lisa S Scott

{"title":"Infant dominant rhythm desynchronization to faces and objects.","authors":"Mina Elhamiasl, Maeve R Boylan, Ryan Barry-Anwar, Zoe Pestana, Andreas Keil, Lisa S Scott","doi":"10.1093/cercor/bhaf087","DOIUrl":"https://doi.org/10.1093/cercor/bhaf087","url":null,"abstract":"Infants' electroencephalography (EEG) dominant rhythm oscillates between 6 and 9 Hz. The desynchronization of this rhythm from baseline to the processing of visual stimuli is used as an index to better understand the development of visual attention. However, development trajectories of desynchronization remain underexplored. Additionally, it is unclear whether development of desynchronization is sensitive to task demands or if it reflects broader developmental changes. To investigate these questions, EEG data were collected from infants aged 6, 9, and 12 months while they passively viewed a fixation cross followed by 10-s trials of a female face or novel object tracked down the screen. Dominant rhythm desynchronization was calculated by subtracting power during the fixation period from power during each task condition. The results revealed significant desynchronization in response to faces at occipital electrodes for all age groups. The magnitude of the desynchronization also increased from 6 to 9 to 12 months of age in response to faces over right occipital electrodes. No significant desynchronization was observed for object stimuli. These findings suggest that dominant rhythm desynchronization develops across infancy and is sensitive to stimulus type. The increased desynchronization for faces compared to objects highlights infants' general preference for faces relative to objects.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cingulate cortex stimulation drives distinct pupillary responses in rat via recruitment of noradrenergic neurons in the locus coeruleus. 大鼠扣带皮层刺激通过蓝斑的去肾上腺素能神经元的募集来驱动瞳孔的不同反应。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-05-01 DOI: 10.1093/cercor/bhaf085

Vianney Salvi, Gilles Courtand, Philippe de Deurwaerdère, Laura Cardoit, Stéphane Valerio, Sébastien Delcasso, François Georges, Thomas Michelet

{"title":"Cingulate cortex stimulation drives distinct pupillary responses in rat via recruitment of noradrenergic neurons in the locus coeruleus.","authors":"Vianney Salvi, Gilles Courtand, Philippe de Deurwaerdère, Laura Cardoit, Stéphane Valerio, Sébastien Delcasso, François Georges, Thomas Michelet","doi":"10.1093/cercor/bhaf085","DOIUrl":"https://doi.org/10.1093/cercor/bhaf085","url":null,"abstract":"The organization of the cingulate cortex has been the subject of intensive studies, concluding to its central role in motor control, cognition, and arousal. One of the key anatomical pathways through which the cingulate cortex influences behavior is its efferent connection to the locus coeruleus (LC). This brainstem region is responsible for noradrenaline (NA) release and is critical for various cognitive and behavioral functions. However, the specific impact of cingulate subregions on the LC-NA system remains unexplored. This study investigated how the different cingulate cortex areas affect LC-NA activity by measuring pupil-evoked responses (PERs) as an index of LC-NA activity. Using intra-cortical stimulation across the eight cingulate areas in rats, we found that anterior cingulate cortex and midcingulate cortex subregions evoked rare autonomic responses but significant pupil dilations whose amplitude increased along the caudo-rostral and dorso-ventral axes. By using the DSP-4, a neurotoxin-selective ablation of the LC-NA system, we suppressed PER and confirmed the role of LC-NA activity in this response. The differential influence of cortical areas on the PER demonstrates that each subregion of the rat cingulate cortex has the potential to differentially activate the LC-NA system, suggesting a clear parcellation of the rodent cingulate cortex, likely corresponding to functional specialization.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visual cortical thickness increases with prolonged artificial vision restoration. 视觉皮质厚度随人工视力恢复时间延长而增加。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-05-01 DOI: 10.1093/cercor/bhaf104

Noelle R B Stiles, Jeiran Choupan, Hossein Ameri, Vivek R Patel, Yonggang Shi

{"title":"Visual cortical thickness increases with prolonged artificial vision restoration.","authors":"Noelle R B Stiles, Jeiran Choupan, Hossein Ameri, Vivek R Patel, Yonggang Shi","doi":"10.1093/cercor/bhaf104","DOIUrl":"10.1093/cercor/bhaf104","url":null,"abstract":"The Argus II retinal prosthesis restores visual perception to late blind individuals. It has been shown that structural changes occur in the brain due to late-onset blindness, including cortical thinning in visual cortical regions. Following vision restoration, it is not yet known whether visual regions are reinvigorated and regain a normal cortical thickness or retain the diminished thickness from blindness. We evaluated the cortical thicknesses of 10 Argus II participants, 10 blind participants, and 13 sighted participants. The Argus II patients on average had a thicker left cuneus cortex and lateral occipital cortex relative to the blind patients. The duration of the Argus II use significantly partially correlated with thicker visual cortical regions in the left hemisphere. Furthermore, in the 2 case studies (scanned before and after implantation), the patient with longer device use (44.5 months) had an increase in the cortical thickness of visual regions, whereas the shorter-using patient did not (6.5 months). Overall, the Argus II participants' cortical thickness was on average significantly rejuvenated in 2 higher visual regions, and participants using the implant for a longer duration had thicker visual regions. This research raises the possibility of structural plasticity reversing visual cortical atrophy in vision restoration participants.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Group creativity emerges from triple ideation pathways: neurobehavioral evidence from an fNIRS hyperscanning study. 群体创造力来自三重思维途径：来自近红外超扫描研究的神经行为证据。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-05-01 DOI: 10.1093/cercor/bhaf129

Kelong Lu, Xinyue Wang, Xinuo Qiao, Zhenni Gao, Ning Hao

{"title":"Group creativity emerges from triple ideation pathways: neurobehavioral evidence from an fNIRS hyperscanning study.","authors":"Kelong Lu, Xinyue Wang, Xinuo Qiao, Zhenni Gao, Ning Hao","doi":"10.1093/cercor/bhaf129","DOIUrl":"https://doi.org/10.1093/cercor/bhaf129","url":null,"abstract":"This study explored the origins of creative ideas in groups, validating the triple-pathway model of group creative ideation with behavioral and neuroscientific evidence. A total of 123 college student dyads completed a creative ideation task and a contrast task while their brain activity was simultaneously recorded using functional near-infrared spectroscopy. Results identified three distinct ideation pathways-flexibility, persistence, and convergence-that collectively drove group creativity, accompanied by three interbrain synchrony states. STATE2, characterized by enhanced prefrontal-temporal interbrain synchrony, positively predicted group creative performance, whereas STATE3, marked by reduced frontal-parietal interbrain synchrony, negatively predicted it. Specifically, STATE2 facilitated group creativity through three mediating pathways: (1) the flexibility pathway alone, (2) combined flexibility-persistence or flexibility-convergence pathways, and (3) a sequential flexibility-persistence-convergence pathway with chain mediation effects. These findings provide neurobehavioral evidence for the triple-pathway model, underscoring the pivotal role of prefrontal-temporal interbrain synchrony in group creativity. They further demonstrate the dynamic, multi-pathway nature of group creative ideation, showing that a single cohort can flexibly employ three interchangeable pathways to generate novel ideas collaboratively.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144156001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating leadership dilemmas: neural mechanisms balancing social approval and group performance. 引导领导困境：平衡社会认可和群体表现的神经机制。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-05-01 DOI: 10.1093/cercor/bhaf108

Daeeun Kim, JuYoung Kim, Kun Il Kim, Hackjin Kim

引用次数: 0

Slow semantic learning in the cerebral cortex, and its relation to the hippocampal episodic memory system. 大脑皮层缓慢语义学习及其与海马情景记忆系统的关系。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-05-01 DOI: 10.1093/cercor/bhaf107

Edmund T Rolls, Chenfei Zhang, Jianfeng Feng

{"title":"Slow semantic learning in the cerebral cortex, and its relation to the hippocampal episodic memory system.","authors":"Edmund T Rolls, Chenfei Zhang, Jianfeng Feng","doi":"10.1093/cercor/bhaf107","DOIUrl":"https://doi.org/10.1093/cercor/bhaf107","url":null,"abstract":"A key question is how new semantic representations are formed in the human brain and how this may benefit from the hippocampal episodic memory system. Here, we describe the major effective connectivity between the hippocampal memory system and the anterior temporal lobe (ATL) semantic memory system in humans. Then, we present and model a theory of how semantic representations may be formed in the human ATL using slow associative learning in semantic attractor networks that receive inputs from the hippocampal episodic memory system. The hypothesis is that if one category of semantic representations is being processed for several seconds, then a slow short-term memory trace associative biologically plausible learning rule will enable all the components during that time to be associated together in a semantic attractor network. This benefits from the binding of components provided by the hippocampal episodic memory system. The theory is modeled in a four-layer network for view-invariant visual object recognition, followed by a semantic attractor network layer that utilizes a temporal trace associative learning rule to form semantic categories based on the inputs that occur close together in time, using inputs from the hippocampal system or from the world.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The generalizability of cortical area parcellations across early childhood. 儿童早期皮层区域分割的普遍性。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-05-01 DOI: 10.1093/cercor/bhaf116

Jiaxin Cindy Tu, Michael J Myers, Wei Li, Jiaqi Li, Xintian Wang, Donna Dierker, Trevor K M Day, Abraham Snyder, Aidan Latham, Jeanette K Kenley, Chloe M Sobolewski, Yu Wang, Alyssa K Labonte, Eric Feczko, Omid Kardan, Lucille A Moore, Chad M Sylvester, Damien A Fair, Jed T Elison, Barbara B Warner, Deanna M Barch, Cynthia E Rogers, Joan L Luby, Christopher D Smyser, Evan M Gordon, Timothy O Laumann, Adam T Eggebrecht, Muriah D Wheelock

{"title":"The generalizability of cortical area parcellations across early childhood.","authors":"Jiaxin Cindy Tu, Michael J Myers, Wei Li, Jiaqi Li, Xintian Wang, Donna Dierker, Trevor K M Day, Abraham Snyder, Aidan Latham, Jeanette K Kenley, Chloe M Sobolewski, Yu Wang, Alyssa K Labonte, Eric Feczko, Omid Kardan, Lucille A Moore, Chad M Sylvester, Damien A Fair, Jed T Elison, Barbara B Warner, Deanna M Barch, Cynthia E Rogers, Joan L Luby, Christopher D Smyser, Evan M Gordon, Timothy O Laumann, Adam T Eggebrecht, Muriah D Wheelock","doi":"10.1093/cercor/bhaf116","DOIUrl":"10.1093/cercor/bhaf116","url":null,"abstract":"The cerebral cortex consists of distinct areas that develop through intrinsic embryonic patterning and postnatal experiences. Accurate parcellation of these areas in neuroimaging studies improves statistical power and cross-study comparability. Given significant brain changes in volume, microstructure, and connectivity during early life, we hypothesized that cortical areas in 1- to 3-year-olds would differ markedly from neonates and increasingly resemble adult patterns as development progresses. Here, we parcellated the cerebral cortex into putative areas using local functional connectivity (FC) gradients in 92 toddlers at 2 years old. We demonstrate high reproducibility of these cortical areas across 1- to 3-year-olds in two independent datasets. The area boundaries in 1- to 3-year-olds were more similar to those in adults than those in neonates. While the age-specific group area parcellation better fits the underlying FC in individuals during the first 3 years, adult area parcellations still have utility in developmental studies, especially in children older than 6 years. Additionally, we provide connectivity-based community assignments of the area parcels, showing fragmented anterior and posterior components based on the strongest connectivity, yet alignment with adult systems when weaker connectivity was included.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0