Catheterization and Cardiovascular Interventions最新文献

{"title":"Low-Dose Colchicine for Secondary Prevention in Patients With Chronic Coronary Syndrome: A Multicenter Real-World Study","authors":"Ecem Gürses,&nbsp;Mustafa Doğduş,&nbsp;Umut Uyan,&nbsp;Ahmet Öz,&nbsp;Shabnam Javadova,&nbsp;Gökçe Nur Durmuş İlhan,&nbsp;Gizem Çabuk,&nbsp;Fatih Sivri,&nbsp;Mehdi Zoghi,&nbsp;İlker Gül","doi":"10.1002/ccd.70662","DOIUrl":"10.1002/ccd.70662","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Chronic coronary syndrome (CCS) remains associated with recurrent ischemic symptoms and impaired quality of life despite contemporary guideline-directed medical therapy. Low-dose colchicine has demonstrated prognostic benefits in randomized trials; however, real-world data regarding its effects on functional capacity and angina-related outcomes are limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This multicenter, real-world observational study included 614 patients with CCS receiving low-dose colchicine therapy for secondary prevention. Functional capacity and angina-related quality of life were assessed before and after colchicine treatment using the Seattle Angina Questionnaire. Changes in daily physical activities, angina frequency, nitroglycerin use, treatment satisfaction, and Canadian Cardiovascular Society (CCS) angina class were evaluated. Clinical outcomes and tolerability, including hospitalization, revascularization, and gastrointestinal adverse effects, were also analyzed. A clinically meaningful improvement was defined as a ≥ 10-point increase in the composite Seattle Angina Questionnaire score.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean age of the study population was 68.8 ± 11.5 years, and 70.5% of patients were male. Following colchicine therapy, significant improvements were observed in functional capacity, including walking on level ground, household activities, and carrying heavy objects (all <i>p</i> &lt; 0.001). Angina frequency scores improved, accompanied by reduced nitroglycerin use (<i>p</i> &lt; 0.001). Treatment satisfaction increased and limitations in enjoyment of life decreased significantly (<i>p</i> &lt; 0.001). CCS angina class decreased from 2.61 ± 0.7 to 1.4 ± 0.62 (<i>p</i> &lt; 0.001). A clinically meaningful improvement in SAQ score was observed in 78.7% of patients. During follow-up, hospitalization occurred in 9.0% of patients, revascularization in 4.4%, and gastrointestinal adverse effects were reported in 9.4%.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In a multicenter real-world cohort of patients with chronic coronary syndrome, low-dose colchicine therapy was associated with significant improvements in functional capacity, angina severity, and quality of life, with an acceptable safety profile. The high rate of clinically meaningful patient-reported improvement further supports colchicine as an effective adjunctive therapy for secondary prevention and symptom control in routine clinical practice.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"108 2","pages":"395-401"},"PeriodicalIF":1.9,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147990741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Aortic Valve Implantation for Pseudoaneurysm of the Mitral-Aortic Intervalvular Fibrosa Causing Severe Aortic Regurgitation","authors":"Paula Vela Martín,&nbsp;Arturo Garcia-Touchard,&nbsp;Vanessa Moñivas Palomero,&nbsp;Juan Francisco Oteo Dominguez","doi":"10.1002/ccd.70673","DOIUrl":"10.1002/ccd.70673","url":null,"abstract":"<div>\u0000 \u0000 <p>Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (P-MAIVF) is a rare complication following infective endocarditis or valve surgery. We report the case of a 65-year-old male who developed a P-MAIVF following surgical mitral valve replacement for infective endocarditis. Shortly after the surgery, although the patient remained afebrile and blood cultures were negative, routine transthoracic echocardiography revealed new-onset severe aortic regurgitation. Multimodality imaging confirmed a P-MAIVF extending into the non-coronary sinus and the left ventricular outflow tract, causing valvular incompetence despite a structurally normal aortic valve. Given the prohibitive surgical risk, an off-label transcatheter aortic valve implantation (TAVI) using a 34 mm self-expanding Evolut FX prosthesis was performed, aiming to exclude the pseudoaneurysm. Despite technical challenges related to the absence of annular calcification and catheter misplacement into the pseudoaneurysm, the prosthesis was successfully implanted with full exclusion of the pseudoaneurysm. At 3-month follow-up, the patient remained asymptomatic, with no residual aortic regurgitation and complete exclusion of the P-MAIVF on CTA. To our knowledge, this is the first reported case of a native, non-calcified aortic root pseudoaneurysm causing severe aortic regurgitation successfully treated with off-label TAVI. Multimodal imaging and careful preprocedural planning were key to procedural success.</p>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"108 2","pages":"446-451"},"PeriodicalIF":1.9,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148045241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Microvasculature: The Index of Microcirculatory Resistance and Its Expanding Role in Cardiovascular Care","authors":"Joanna Sohn,&nbsp;Matthew A. Soderstrom,&nbsp;Ariana Ramirez,&nbsp;John-Henry Dean,&nbsp;Raj Shah,&nbsp;Debanshu Roy,&nbsp;Kenneth Stone,&nbsp;Ariel Vinas,&nbsp;Bryan Ramsey,&nbsp;Charles Lin,&nbsp;Robert Chilton","doi":"10.1002/ccd.70629","DOIUrl":"10.1002/ccd.70629","url":null,"abstract":"<p>Index of microcirculatory resistance (IMR) is a cutting-edge, wire-based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health. IMR has been shown to be of particular use as a diagnostic tool in the assessment of coronary microvascular dysfunction (CMD) allowing for diagnostic clarification in conditions like ischemia with non-obstructive coronary arteries (INOCA), acute coronary syndrome (ACS), and post-percutaneous coronary intervention (PCI) complications. In addition to its ability to be used as a powerful diagnostic tool, it also serves as a prognostic tool, helping to predict which patients are at elevated risk of major adverse cardiovascular events (MACE) and mortality. With the increasing integration of artificial intelligence into the cath lab, previous sources of error in IMR, such as technical variability and hemodynamic influences, are no longer as significant of an issue and allow for greater precision in the use of this tool. This comprehensive review discusses the physiologic basis of IMR, measurement techniques, and diagnostic and prognostic capabilities of IMR, while highlighting its therapeutic potential and future applications.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"108 2","pages":"287-300"},"PeriodicalIF":1.9,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccd.70629","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147871326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral Embolic Protection in TAVI: Mechanistic and Temporal Limitations","authors":"Ashish H. Shah","doi":"10.1002/ccd.70651","DOIUrl":"10.1002/ccd.70651","url":null,"abstract":"","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"108 2","pages":"329-330"},"PeriodicalIF":1.9,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147937105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Value of Computational Pressure-Flow Dynamics Derived FFR Measured Immediately After Successful Paclitaxel‑Coated Balloon Angioplasty for In-Stent Restenosis Lesion","authors":"Wangwei Yang,&nbsp;Xingqiang He,&nbsp;Jianzheng Liu,&nbsp;Fangjun Mou,&nbsp;Yi Liu,&nbsp;Zhiyong Yin,&nbsp;Fei Li,&nbsp;Jingyu Zhou,&nbsp;Haokao Gao,&nbsp;Tao Hu,&nbsp;Robert-Jan van Geuns,&nbsp;Yoshinobu Onuma,&nbsp;Patrick W. Serruys,&nbsp;Chao Gao,&nbsp;Ling Tao","doi":"10.1002/ccd.70653","DOIUrl":"10.1002/ccd.70653","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The clinical impact of angiography-based, computational pressure-flow dynamics derived FFR (caFFR) after paclitaxel‑coated balloon (DCB) angioplasty remains unclear.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>To investigate the prognostic value of post-procedural caFFR in the treatment of in-stent restenosis (ISR) with DCB.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Consecutive patients undergoing DCB angioplasty for ISR at Xijing Hospital, China, between December 2015 and December 2019 were prospectively enrolled. The primary endpoint was vessel-oriented composite endpoint (VoCE), defined as a composite of vessel-related cardiovascular death, target-vessel myocardial infarction (TV-MI), and ischemia-driven target vessel revascularization (ID-TVR) at 3-year, assessed at the vessel level.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 1055 vessels treated with DCB were screened, and the post-procedural caFFR was analyzable in 999 (94.7%). At 3-year, 149 VoCE (14.9%) and 98 ID-TVR (9.8%) events occurred. Maximally-selected log-rank statistics respectively identified post-procedural caFFR value of 0.87 and post-procedural %DS of 28 as the optimal cutoff points to predict VoCE. Post-procedural caFFR demonstrates the superior predictive ability for VoCE compared to post-procedural %DS (NRI: 7.4%, <i>p</i> &lt; 0.001). A negative correlation was discerned between post-procedural caFFR value and VoCE (HR_{per 0.1 increase}: 0.72, 95% CI: 0.53–0.98, <i>p</i> = 0.039). Post-procedural caFFR ≤ 0.87 group was associated with a 1.5-fold increase in the risk of VoCE (HR_IPTW: 1.53, 95% CI: 1.02–2.29) and a 1.8-fold increase in ID-TVR (HR_IPTW: 1.82, 95% CI: 1.15–2.89).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>A higher post-procedural caFFR value is associated with improved vessel-related clinical outcomes in patients of ISR treated by DCB. Achieving a post-procedural caFFR value of 0.87 in the treated vessels may represent a reasonable procedural goal.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>Clinicaltrial.gov identifier: NCT05133921</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"108 2","pages":"376-387"},"PeriodicalIF":1.9,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147966918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radial Versus Femoral Access for Diagnostic Coronary Angiography: Insights From a Tertiary Academic Center in Johannesburg","authors":"Khulasande Liso Ntaka,&nbsp;Dineo Mpanya,&nbsp;Umar G Adamu,&nbsp;Thomas Kalk,&nbsp;Nqoba Tsabedze","doi":"10.1002/ccd.70654","DOIUrl":"10.1002/ccd.70654","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The radial artery is the preferred access for performing diagnostic coronary angiograms (DCA). However, data on the safety and efficacy of radial compared to femoral access in low- and middle-income countries is limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This study aims to evaluate the safety and efficacy of radial versus femoral access in patients referred for a DCA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted a cross-sectional, retrospective study on patients referred for DCA to evaluate the safety and efficacy of radial versus femoral access routes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study population comprised 653 patients with a mean age of 58.2 ± 12.7 years, of which 408 (62.5%) were males. Radial access was utilized in 318 (48.7%) patients. The median duration of the radial access was 50 min (Interquartile range [IQR]: 40–60) and was longer than that of the femoral artery access, which had a median duration of 45 min (IQR: 35–60) (<i>p</i> = 0.010). The median total radiation dose emitted during the DCA in the femoral access group was 3511 milligray per square meter (mGy/m²), (IQR: 2154–5821), and patients in the radial access group received a median radiation dose of 4011 mGy/m² (IQR: 2298–6411) (<i>p</i> = 0.0661). The mean contrast volume administered in the radial and femoral artery access group did not differ significantly, measuring 83.7 ± 36.1 milliliters (mL) and 88.9 ± 37.1 mL, respectively (<i>p</i> = 0.073).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Radial access was used in nearly half of all DCA, reflecting its growing adoption in clinical practice. These findings support the use of radial access as a safe and viable alternative to femoral access, even in resource-limited settings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"108 2","pages":"437-445"},"PeriodicalIF":1.9,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccd.70654","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148038991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebrovascular Events in Aortic Stenosis: From Native Valve Disease to TAVR-Specific Risk and Prevention","authors":"Priyanka Boettger,&nbsp;Jamschid Sedighi,&nbsp;Martin Juenemann,&nbsp;Omar Alhaj-Omar,&nbsp;Kerstin Piayda,&nbsp;Mani Arsalan,&nbsp;Samuel Sossalla,&nbsp;Won-Keun Kim","doi":"10.1002/ccd.70660","DOIUrl":"10.1002/ccd.70660","url":null,"abstract":"<p>Aortic stenosis (AS) is associated with a heightened burden of cardiovascular comorbidities, atrial fibrillation (AF), and progressive valvular calcification, all of which may contribute to cerebrovascular events across the disease continuum. However, true epidemiologic evidence establishing AS as an independent stroke risk factor remains limited, and much of the contemporary concern regarding stroke has shifted toward interventional management. Transcatheter aortic valve replacement (TAVR) has become the dominant therapy for severe AS, but periprocedural and early postprocedural stroke remain among its most clinically significant complications. This review integrates current knowledge on stroke pathways in native AS, AF, calcific embolization, hemodynamic alterations, and places them in context with procedural mechanisms unique to TAVR. We summarize evidence comparing stroke rates in TAVR versus surgical aortic valve replacement and examine anatomic, procedural, and patient-level drivers of embolic risk. Building on these mechanisms, we highlight contemporary stroke mitigation strategies including multimodality imaging for preprocedural planning, optimization of access and device selection, cerebral embolic protection devices, antithrombotic therapy tailored to individual indications, and structured postprocedural neurologic and rhythm monitoring. By integrating the natural history of AS with TAVR-specific embolic pathways, this review provides a comprehensive framework for understanding and minimizing stroke risk in patients across the spectrum of AS.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"108 2","pages":"331-342"},"PeriodicalIF":1.9,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccd.70660","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147937063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Long-Term Effects of Percutaneous Balloon Mitral Valvotomy (PBMV) in 90 Patients With Rheumatic Mitral Stenosis: A Retrospective Analysis","authors":"Jian Xu,&nbsp;Ning Liang,&nbsp;Yongqi Xiao,&nbsp;Xuenuo Wu,&nbsp;Dong Lu,&nbsp;Chunping Li,&nbsp;Yizhou Zeng,&nbsp;Xiyuan Luo","doi":"10.1002/ccd.70576","DOIUrl":"10.1002/ccd.70576","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Analysis of the long-term effects of percutaneous balloon mitral valvotomy (PBMV) intervention in patients with rheumatic mitral stenosis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>To evaluate the long-term efficacy, safety, and hemodynamic outcomes of PBMV in patients with rheumatic heart disease and mitral stenosis through a 6-year retrospective clinical follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Ninety patients with rheumatic mitral stenosis treated in our hospital from January 2012 to 2017 were selected retrospectively. The changes of cardiac function grade before and 1, 3, and 6 years after intervention, left atrial diameter (LADd), mitral valve area (MVA), transvalvular pressure difference (MVG), pulmonary artery systolic pressure (PAPs), left ventricular ejection fraction (LVEF), and restenosis 1, 3, and 6 years after intervention were observed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Post-procedural NYHA functional class improved significantly compared with baseline (<i>p</i> &lt; 0.05). NYHA class remained stable across 1-, 3-, and mid-term (6-year) follow-up visits, with no statistically significant differences between these time points. After 6 years of intervention, MVA and LVEF were still higher than those before intervention, while LADd, MVG, and PAPs were still lower than those before intervention (<i>p</i> &lt; 0.05). There was no significant difference between the study cohort in terms of restenosis, complications, and cardiac adverse events at 1, 3, and 6 years after intervention (<i>p</i> &gt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The long-term effect of PBMV is good in patients with rheumatic mitral stenosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"108 1","pages":"124-129"},"PeriodicalIF":1.9,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Percutaneous Revascularization for Acute Myocardial Infarction From Left Main Occlusion and Concomitant Right Coronary Artery Chronic Total Occlusion: A Case Report","authors":"Zhipeng Zhou,&nbsp;Yanlei He,&nbsp;Yibin Pan,&nbsp;Juncang Duan","doi":"10.1002/ccd.70624","DOIUrl":"10.1002/ccd.70624","url":null,"abstract":"<div>\u0000 \u0000 <p>Despite its rarity, acute occlusion of the left main coronary artery is associated with an exceedingly high mortality rate. This report describes a critical case of acute myocardial infarction <b>(</b>AMI) caused by acute total occlusion of the left main (LM) artery, complicated by a chronic total occlusion (CTO) of the proximal right coronary artery (RCA). A 55-year-old Chinese male with hypertension and a heavy smoking history presented with sudden chest pain. The initial electrocardiogram (ECG) showed ST-segment elevation in leads V1–V6 and aVR, indicative of anterior wall AMI, and the patient was in cardiogenic shock. Emergency coronary angiography revealed total occlusion of the LM artery and a CTO of the proximal RCA. Primary percutaneous coronary intervention (PCI) was successfully performed on the LM artery, with three stents implanted to restore TIMI grade 3 flow. An intra-aortic balloon pump (IABP) was inserted for circulatory support. Post-procedurally, the patient experienced ventricular fibrillation but was successfully resuscitated. The hospital course was complicated by acute renal failure, gastrointestinal bleeding, and severe sepsis. After 55 days of intensive care, the patient was discharged with marked clinical improvement, albeit with severely impaired left ventricular function (ejection fraction 25%). The patient survived at the 6-month follow-up.</p>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"108 1","pages":"6-11"},"PeriodicalIF":1.9,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147679908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Repair of Sinus Venosus Defect Using a 12-zig Covered Cheatham-Platinum Stent in Large Superior Vena Cava—Right Atrium Junctions: Early Multicenter Experience","authors":"Alberto Fuensalida,&nbsp;Eric Rosenthal,&nbsp;Saleha Kabir,&nbsp;Gergely Szantho,&nbsp;Sophia Yong,&nbsp;Demetris Taliotis,&nbsp;Mark Turner,&nbsp;Radwa Bedair","doi":"10.1002/ccd.70623","DOIUrl":"10.1002/ccd.70623","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 <p>Sinus venosus defect (SVD) is a rare congenital heart anomaly characterised by an abnormal communication between the atria, often associated with partial anomalous pulmonary venous connection (PAPVC). Traditional surgical repair carries significant risks, prompting exploration into less invasive transcatheter approaches.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 <p>This study aims to evaluate the efficacy and safety of a 12-zig covered Cheatham-platinum stent for the correction of SVD, particularly in patients with enlarged superior vena caval-right atrial (SVC-RA) junctions unsuitable for standard stenting techniques.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 <p>A retrospective analysis was conducted on five symptomatic patients treated with the 12-zig CP stent across two institutions. Preprocedural imaging, including echocardiograms, cardiac MRIs, and CT angiograms was performed to assess right ventricular function and define anatomical relationships. The procedures were guided by transoesophageal echocardiography (TOE) and involved balloon sizing to ensure optimal stent placement. All five patients (80% male, median age 59 years) successfully underwent stent implantation. A second stent was required in three cases due to residual leaks, which were effectively sealed, and in one case for stent stability. No procedural complications were reported, and all patients experienced symptomatic improvement at follow-up, with imaging confirming stable stent positions. The 12-zig CP stent demonstrates feasibility in the percutaneous treatment of highly selected patients with SVD, allowing for effective closure in complex anatomies, including large SVC-RA junctions. This study underscores the potential of advanced imaging techniques and tailored interventions in enhancing patient outcomes with complex congenital heart disease previously unsuitable for standard transcatheter approaches.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"108 1","pages":"104-113"},"PeriodicalIF":1.9,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccd.70623","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147794721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}