Catheterization and Cardiovascular Interventions最新文献

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Differences between sexes in STEMI treatment and outcomes with contemporary primary PCI. STEMI 治疗中的性别差异和当代初级 PCI 的疗效。
IF 2.1 3区 医学
Catheterization and Cardiovascular Interventions Pub Date : 2024-11-01 Epub Date: 2024-09-03 DOI: 10.1002/ccd.31206
Michael L Savage, Karen Hay, William Vollbon, Dale J Murdoch, Christopher Hammett, James Crowhurst, Karl Poon, Rohan Poulter, Darren L Walters, Russell Denman, Isuru Ranasinghe, Owen Christopher Raffel
{"title":"Differences between sexes in STEMI treatment and outcomes with contemporary primary PCI.","authors":"Michael L Savage, Karen Hay, William Vollbon, Dale J Murdoch, Christopher Hammett, James Crowhurst, Karl Poon, Rohan Poulter, Darren L Walters, Russell Denman, Isuru Ranasinghe, Owen Christopher Raffel","doi":"10.1002/ccd.31206","DOIUrl":"10.1002/ccd.31206","url":null,"abstract":"<p><strong>Background: </strong>Historically, differences in timely reperfusion and outcomes have been described in females who suffer ST-segment elevation myocardial infarction (STEMI). However, there have been improvements in the treatment of STEMI patients with contemporary Percutaneous Coronary Intervention (PCI) strategies.</p><p><strong>Methods: </strong>Comparisons between sexes were performed on STEMI patients treated with primary PCI over a 4-year period (January 1, 2017-December 31, 2020) from the Queensland Cardiac Outcomes Registry. Primary outcomes were 30-day and 1-year cardiovascular mortality. Secondary outcomes were STEMI performance measures. The total and direct effects of gender on mortality outcomes were estimated using logistic and multinomial logistic regression models.</p><p><strong>Results: </strong>Overall, 2747 (76% male) were included. Females were on average older (65.9 vs. 61.9 years; p < 0.001), had longer total ischemic time (69 min vs. 52 min; p < 0.001) and less achievement of STEMI performance targets (<90 min) (50% vs. 58%; p < 0.001). There was no evidence for a total (odds ratio [OR] 1.3 (95% confidence interval [CI]: 0.8-2.2; p = 0.35) or direct (adjusted OR 1.2 (95% CI: 0.7-2.1; p = 0.58) effect of female sex on 30-day mortality. One-year mortality was higher in females (6.9% vs. 4.4%; p = 0.014) with total effect estimates consistent with increased risk of cardiovascular mortality (Incidence rate ratio [IRR]: 1.5; 95% CI: 1.0-2.3; p = 0.059) and noncardiovascular mortality (IRR: 2.1; 95% CI: 0.9-4.7; p = 0.077) in females. However, direct (adjusted) effect estimates of cardiovascular mortality (IRR: 1.0; 95% CI: 0.6-1.6; p = 0.94) indicated sex differences were explained by confounders and mediators.</p><p><strong>Conclusion: </strong>Small sex differences in STEMI performance measures still exist; however, with contemporary primary PCI strategies, sex is not associated with cardiovascular mortality at 30 days or 1 year.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142124942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The "Cuttering (Cutting-Dottering Balloon) Technique" for treatment of flow-limiting coronary intramural hematoma. 用于治疗限制血流的冠状动脉壁内血肿的 "切割(切割-点蚀球囊)技术"。
IF 2.1 3区 医学
Catheterization and Cardiovascular Interventions Pub Date : 2024-11-01 Epub Date: 2024-09-26 DOI: 10.1002/ccd.31231
Gabriele Luigi Gasparini, Matteo Maurina, Damiano Regazzoli, Paolo Canova, Pier Pasquale Leone, Antonio Mangieri, Bernhard Reimers
{"title":"The \"Cuttering (Cutting-Dottering Balloon) Technique\" for treatment of flow-limiting coronary intramural hematoma.","authors":"Gabriele Luigi Gasparini, Matteo Maurina, Damiano Regazzoli, Paolo Canova, Pier Pasquale Leone, Antonio Mangieri, Bernhard Reimers","doi":"10.1002/ccd.31231","DOIUrl":"10.1002/ccd.31231","url":null,"abstract":"<p><strong>Background: </strong>Coronary artery dissections are caused by a tear in the vessel endothelium, resulting in blood extravasation into the subintimal space, with subsequent intramural hematoma (IMH). One potential technique to deal with this complication is the use of cutting balloons, however, a significant number of cases experienced distal propagation of the hematoma. We describe a novel technique that enhances the possibility of creating intimal tears between the false and true lumen, aiding in hematoma drainage and restoring distal coronary flow.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of seven consecutive patients who underwent percutaneous coronary intervention complicated by flow-limiting intramural hematomas. All patients were treated using the \"Cuttering Technique,\" based on the operators' preference. Procedural success was defined as achieving a distal thrombolysis in myocardial infarction 3 (TIMI 3) flow.</p><p><strong>Results: </strong>In five out of seven patients treated with \"Cuttering Technique\" we observed a complete restoration of TIMI 3 flow into the dissected segment.</p><p><strong>Conclusions: </strong>Our cases show the effectiveness of the \"Cuttering Technique\" as a viable approach for managing IMHs. This technique enhances the possibility of creating intimal tears between the false and true lumens, aiding in hematoma drainage and restoring distal coronary flow.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using a customized telescoped stent complex in the percutaneous treatment of a residual superior sinus venosus defect. 使用定制的伸缩式支架复合体经皮治疗残余上窦静脉缺损。
IF 2.1 3区 医学
Catheterization and Cardiovascular Interventions Pub Date : 2024-11-01 Epub Date: 2024-08-15 DOI: 10.1002/ccd.31188
Ernesto Mejia, Ryan A Leahy, Jenny E Zablah, Gareth J Morgan
{"title":"Using a customized telescoped stent complex in the percutaneous treatment of a residual superior sinus venosus defect.","authors":"Ernesto Mejia, Ryan A Leahy, Jenny E Zablah, Gareth J Morgan","doi":"10.1002/ccd.31188","DOIUrl":"10.1002/ccd.31188","url":null,"abstract":"<p><p>The management of superior sinus venosus defects (SVD) via transcatheter covered stent (CS) placement is becoming an acceptable alternative to open heart surgery. Though the medium-term success of this procedure has been described, residual shunting from damage to the covering of the implanted stents, use of stents which are too short and unanticipated shortening of stents may result in immediate or short-term procedural failure. In such cases, placement of a second CS may be required to address a residual defect. Preprocedural prediction of the length of stent required for residual leak treatment may not be as accurate as predicting the required stent length in a native defect, meaning that compassionate use applications to facilitate acquiring non-standard stent and balloon combinations may not be practical. We present a successful case of residual SVD closure using a novel sutured telescoping stent technique. Further collaboration with industry should encourage regulatory approval of longer CS, to mitigate the need for potentially unpredictable modifications such as this.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141987502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endovascular versus surgical revascularization for patients with chronic limb-threatening ischemia: A systematic review and meta-analysis of randomized controlled trials. 针对慢性肢体缺血患者的血管内再通术与外科再通术:随机对照试验的系统回顾和荟萃分析。
IF 2.1 3区 医学
Catheterization and Cardiovascular Interventions Pub Date : 2024-11-01 Epub Date: 2024-08-20 DOI: 10.1002/ccd.31200
Akshay Machanahalli Balakrishna, Venkata Mahesh Alla, Herbert D Aronow, Eric Secemsky, S Elissa Altin, Sasanka Jayasuriya, Andrew M Goldsweig
{"title":"Endovascular versus surgical revascularization for patients with chronic limb-threatening ischemia: A systematic review and meta-analysis of randomized controlled trials.","authors":"Akshay Machanahalli Balakrishna, Venkata Mahesh Alla, Herbert D Aronow, Eric Secemsky, S Elissa Altin, Sasanka Jayasuriya, Andrew M Goldsweig","doi":"10.1002/ccd.31200","DOIUrl":"10.1002/ccd.31200","url":null,"abstract":"","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142006271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optical coherence tomography characterization of degradation kinetics between second- and third-generation resorbable magnesium scaffold. 第二代和第三代可吸收镁支架降解动力学的光学相干断层扫描表征。
IF 2.1 3区 医学
Catheterization and Cardiovascular Interventions Pub Date : 2024-11-01 Epub Date: 2024-09-23 DOI: 10.1002/ccd.31238
Masaru Seguchi, Philine Baumann-Zumstein, Armin Fubel, Martin Pritsch, Alp Aytekin, Philipp Nicol, Jonas Altevogt, Michael Joner
{"title":"Optical coherence tomography characterization of degradation kinetics between second- and third-generation resorbable magnesium scaffold.","authors":"Masaru Seguchi, Philine Baumann-Zumstein, Armin Fubel, Martin Pritsch, Alp Aytekin, Philipp Nicol, Jonas Altevogt, Michael Joner","doi":"10.1002/ccd.31238","DOIUrl":"10.1002/ccd.31238","url":null,"abstract":"<p><strong>Aims: </strong>This preclinical study aimed to establish optical coherence tomography (OCT)-derived parameters that could be used in the clinical setting for assessing strut degradation in the third-generation drug-eluting resorbable magnesium scaffold (DREAMS-3G), and characterize the comparative degradation profile against its precursor device (Magmaris<sup>TM</sup> scaffold).</p><p><strong>Methods and results: </strong>Twelve DREAMS-3G and 10 Magmaris<sup>TM</sup> scaffolds were implanted in juvenile pigs, and OCT images obtained at baseline and follow-up (6 or 12 months). Strut degradation was assessed by planimetric analysis and compared with OCT-derived indices to validate their diagnostic accuracy. A total of 3327 struts of DREAMS-3G and 2995 struts of the Magmaris<sup>TM</sup> scaffold were delineated by OCT. DREAMS-3G exhibited a significantly higher number of visible struts per analyzed frame at 6 months than the Magmaris<sup>TM</sup> scaffold, in the absence of significant differences at 12 months. Attenuation index (AtI) analysis indicated DREAMS-3G degradation was less advanced at 6 months but more advanced at 12 months compared to the Magmaris<sup>TM</sup> scaffold. These OCT-derived indices significantly correlated with the results of the planimetric analysis.</p><p><strong>Conclusion: </strong>The current preclinical study validated OCT indices that may serve as clinical surrogate markers for scaffold degradation. AtI analysis indicated that DREAMS-3G showed less degradation at 6 months but more advanced degradation at 12 months compared to the Magmaris<sup>TM</sup> scaffold, which corroborates the findings from planimetric analysis.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HydroDynamic contrast Recanalization (HDR): Description of a new crossing technique for coronary chronic total occlusions. 水动力对比再通术(HDR):描述一种治疗冠状动脉慢性全闭塞的新交叉技术。
IF 2.1 3区 医学
Catheterization and Cardiovascular Interventions Pub Date : 2024-11-01 Epub Date: 2024-09-26 DOI: 10.1002/ccd.31243
Mauro Carlino, Angelo Nascimbene, Emmanouil S Brilakis, Akshitha Yarrabothula, Antonio Colombo, Sunao Nakamura, Lorenzo Azzalini, Bashir Hanif, M Bilal Iqbal, Salman A Arain
{"title":"HydroDynamic contrast Recanalization (HDR): Description of a new crossing technique for coronary chronic total occlusions.","authors":"Mauro Carlino, Angelo Nascimbene, Emmanouil S Brilakis, Akshitha Yarrabothula, Antonio Colombo, Sunao Nakamura, Lorenzo Azzalini, Bashir Hanif, M Bilal Iqbal, Salman A Arain","doi":"10.1002/ccd.31243","DOIUrl":"10.1002/ccd.31243","url":null,"abstract":"<p><strong>Background: </strong>Intraplaque delivery of contrast has been utilized during percutaneous coronary interventions (PCI) of chronic total occlusions (CTO) to delineate anatomy and to facilitate wire crossing. Its utility as a tool to accomplish primary crossing of CTOs has not been described or validated.</p><p><strong>Aims: </strong>We describe a new technique leveraging the diagnostic and therapeutic roles of intraplaque contrast injection to accomplish primary crossing of CTOs: HydroDynamic contrast Recanalization (HDR).</p><p><strong>Methods: </strong>HDR is an antegrade crossing method for coronary CTOs based on the synergistic use of contrast microinjections and polymer jacketed wires. We present a retrospective, first-in-man, case series utilizing HDR for CTO PCI in patients with favorable CTO anatomy (visible proximal segment and identifiable distal target). The primary outcome was procedural success. The secondary outcome was any procedural complications.</p><p><strong>Results: </strong>A total of 43 patients with 45 CTOs underwent CTO PCI with HDR. Mean patient age was 64.3 ± 11 years. The mean Japanese CTO and PROGRESS CTO scores were 2.3 ± 0.7 and 1.8 ± 0.7, respectively. CTO complexity was high, with an ambiguous or blunt cap in 34 occlusions (76%); lesion length ≥ 20 mm in 27 occlusions (60%); and moderate/heavy calcification in 36 occlusions (80%). Procedural success using HDR was 100%. There were no complications.</p><p><strong>Conclusions: </strong>This study shows the utility of HDR in CTO PCI. HDR appears to be a safe and promising new contrast-based primary crossing technique in selected patients. This strategy warrants further evaluation in larger prospective studies.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CT-derived simulations to predict outcomes in patients undergoing transcatheter aortic valve implantation with an ACURATE Neo2 valve the PRECISE-TAVI cohort B trial. 通过CT模拟预测接受ACURATE Neo2瓣膜经导管主动脉瓣植入术的患者预后的PRECISE-TAVI B组试验。
IF 2.1 3区 医学
Catheterization and Cardiovascular Interventions Pub Date : 2024-11-01 Epub Date: 2024-08-28 DOI: 10.1002/ccd.31194
Thijmen W Hokken, Philippe Nuyens, Claudio Ruffo, Rutger-Jan Nuis, Joost Daemen, Isabella Kardys, Ricardo Budde, Nicola Buzzatti, Ole de Backer, Nicolas M Van Mieghem
{"title":"CT-derived simulations to predict outcomes in patients undergoing transcatheter aortic valve implantation with an ACURATE Neo2 valve the PRECISE-TAVI cohort B trial.","authors":"Thijmen W Hokken, Philippe Nuyens, Claudio Ruffo, Rutger-Jan Nuis, Joost Daemen, Isabella Kardys, Ricardo Budde, Nicola Buzzatti, Ole de Backer, Nicolas M Van Mieghem","doi":"10.1002/ccd.31194","DOIUrl":"10.1002/ccd.31194","url":null,"abstract":"<p><strong>Background: </strong>Paravalvular leakage (PVL) and conduction disorders that require permanent pacemaker implantation (PPI) remain clinically relevant challenges after transcatheter aortic valve implantation (TAVI). Computed tomography-based simulations may predict the risk of significant PVL and PPI.</p><p><strong>Aims: </strong>To evaluate the feasibility and accuracy of preprocedural computer simulation with FEops HEARTguide™ to predict >trace PVL and PPI after TAVI with the self-expanding supra-annular ACURATE Neo2 transcatheter heart valve.</p><p><strong>Methods: </strong>Prospective multicenter observational study that included consecutive patients undergoing TAVI with an ACURATE Neo2 valve. Computer simulations were performed before the TAVI procedure as part of the preprocedural planning. Follow-up period for PPI and PVL was 30 days.</p><p><strong>Results: </strong>Sixty-five patients were included (median age 81 years (25th-75th percentile 77-84.5)). New left bundle branch block occurred in five patients (7.7%) and PPI in two patients (3%). Contact pressure index (CPI) was similar for patients with vs without new conduction disorders. Patients with PPI had numerically higher CPI than those without PPI (median CPI 20.0% (25th-75th percentile 15.0-25.0) vs. 13.0% (25th-75th percentile 5.5-18), p = 0.27). More than trace PVL occurred in 30%. Median PVL was significantly lower in patients with none-trace PVL (3.2 mL/s [25th-75th percentile 2.2-5.0]), compared to mild PVL (5.2 mL/s [25th-75th percentile 3.2-10.3]) and moderate PVL (12.6 mL/s [25th-75th percentile 3.9-21.3])(p = 0.036). A simulated PVL-cutoff of 9.65 mL/s identified patients with >trace PVL (AUC 0.70 (95% CI 0.55-0.85), sensitivity 42%, specificity 95%).</p><p><strong>Conclusion: </strong>In our study FEops HEARTguide™ simulations identified patients at risk for >trace PVL with ACURATE Neo2 TAVI but not for PPI.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142079284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcatheter aortic valve implantation for severe aortic regurgitation using the J-Valve system: A midterm follow-up study. 使用 J-Valve 系统经导管主动脉瓣植入术治疗严重主动脉瓣反流:中期随访研究。
IF 2.1 3区 医学
Catheterization and Cardiovascular Interventions Pub Date : 2024-11-01 Epub Date: 2024-09-09 DOI: 10.1002/ccd.31196
Min Jin, Haitao Zhang, Qing Zhou, Shuchun Li, Dongjin Wang
{"title":"Transcatheter aortic valve implantation for severe aortic regurgitation using the J-Valve system: A midterm follow-up study.","authors":"Min Jin, Haitao Zhang, Qing Zhou, Shuchun Li, Dongjin Wang","doi":"10.1002/ccd.31196","DOIUrl":"10.1002/ccd.31196","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter aortic valve implantation (TAVI) is a well-established intervention for severe aortic valve stenosis. However, its application for severe aortic regurgitation (AR) is still under evaluation. This study aims to present the 3-year follow-up outcomes of the J-Valve system in managing severe AR.</p><p><strong>Aims: </strong>The aim of this study was to evaluate the mid-term efficacy and durability of the J-Valve system in the treatment of severe AR and to provide new information on this intervention.</p><p><strong>Methods: </strong>In this retrospective, single-center study, we evaluated the prognostic outcomes of patients with AR, who underwent treatment with the J-Valve system at Nanjing Drum Tower Hospital. Consecutive patients who were treated with the J-Valve were included in the analysis. The study focused on the echocardiographic follow-up to assess the effectiveness and durability of the J-Valve system in managing AR.</p><p><strong>Results: </strong>From January 2018 to December 2022, 36 high-risk AR patients treated with the J-Valve system had a procedural success rate of 97.2%, with one case requiring open-heart surgery due to valve displacement. Significant improvements were observed in left ventricular diameter (from 63.50 [58.75-69.50] mm to 56.50 [53.00-60.50] mm, p < 0.001) and left atrial diameter (from 44.00 [40.00-45.25] mm to 39.00 [36.75-41.00] mm, p = 0.003) postsurgery. All patients completed the 1-year follow-up, with an overall mortality rate of 2 out of 36 (5.6%). Among the surviving patients, there was one case of III° atrioventricular block and one case of stroke, both occurring within 90 days postsurgery. After a 3-year follow-up, 15.0% of patients had mild or moderate valvular regurgitation, with no cases of moderate or severe paravalvular leak. Additionally, 89.5% of patients were classified as New York Heart Association class I or II, showing significantly enhanced cardiac function.</p><p><strong>Conclusion: </strong>The J-Valve system has shown positive therapeutic outcomes in treating AR, with notable effectiveness in managing the condition and significant improvements in heart failure symptoms and cardiac remodeling. However, due to the limited sample size and partial follow-up data, it is important to emphasize the need for further research with comprehensive long-term follow-up, to fully validate these results.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142153198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elevated myocardial extracellular volume fraction is associated with the development of conduction pathway defects following transcatheter aortic valve replacement. 心肌细胞外体积分数升高与经导管主动脉瓣置换术后传导通路缺陷的发生有关。
IF 2.1 3区 医学
Catheterization and Cardiovascular Interventions Pub Date : 2024-11-01 Epub Date: 2024-07-02 DOI: 10.1002/ccd.31136
Rafey Feroze, Puneet Kang, Luis Augusto Palma Dallan, Navya Akula, Jason Galo, Sung-Han Yoon, Anene Ukaigwe, Steven J Filby, Cristian Baeza, Marc Pelletier, Gregory Rushing, Sanjay Rajagopalan, Sadeer Al-Kindi, Imran Rashid, Guilherme F Attizzani
{"title":"Elevated myocardial extracellular volume fraction is associated with the development of conduction pathway defects following transcatheter aortic valve replacement.","authors":"Rafey Feroze, Puneet Kang, Luis Augusto Palma Dallan, Navya Akula, Jason Galo, Sung-Han Yoon, Anene Ukaigwe, Steven J Filby, Cristian Baeza, Marc Pelletier, Gregory Rushing, Sanjay Rajagopalan, Sadeer Al-Kindi, Imran Rashid, Guilherme F Attizzani","doi":"10.1002/ccd.31136","DOIUrl":"10.1002/ccd.31136","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Transcatheter aortic valve replacement (TAVR) has become an established method of aortic stenosis treatment but suffers from the risk of heart block and pacemaker requirement. Risk stratification for patients who may develop heart block remains imperfect. Simultaneously, myocardial fibrosis as measured by cardiac magnetic resonance imaging (CMR) has been demonstrated as a prognostic indicator of ventricular recovery and mortality following TAVR. However, the association of CMR-based measures of myocardial fibrosis with post-TAVR conduction disturbances has not yet been explored.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aims: &lt;/strong&gt;We evaluated whether myocardial fibrosis, as measured by late gadolinium enhancement and extracellular volume (ECV) from CMR would be associated with new conduction abnormalities following TAVR.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;One hundred seventy patients who underwent CMR within 2 months before TAVR were retrospectively reviewed. Septal late gadolinium enhancement (LGE) and ECV measurements were made as surrogates for replacement and interstitial fibrosis respectively. New conduction abnormalities were defined by the presence of transient or permanent atrioventricular block, new bundle branch blocks, and need for permanent pacemaker. Association of myocardial fibrosis and new conduction derangements were tested using receiver operator curve (ROC) and regression analysis in patients with and without pre-existing conduction issues.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Forty-six (27.1%) patients developed post-TAVR conduction deficits. ECV was significantly higher among patients who experienced new conduction defects (26.2 ± 3.45% vs. 24.7% ± 4.15%, p value: 0.020). A greater fraction of patients that had new conduction defects had an elevated ECV of ≥26% (54.3% vs. 36.3%, p value: 0.026). ECV ≥ 26% was independently associated with the development of new conduction defects (odds ratio [OR]: 2.364, p value: 0.030). ROC analysis revealed a significant association of ECV with new conduction defects with an area under the receiver operating characteristic curve (AUC) of 0.632 (95% confidence interval: 0.555-0.705, p value: 0.005). The combination of prior right bundle branch block (RBBB) and ECV revealed a greater AUC of 0.779 (0.709-0.839, p value: &lt;0.001) than RBBB alone (Delong p value: 0.049). No association of LGE/ECV with new conduction defects was observed among patients with pre-existing conduction disease. Among patients without baseline conduction disease, ECV was independently associated with the development of new conduction deficits (OR: 3.685, p value: 0.008).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The present study explored the association of myocardial fibrosis, as measured by LGE and ECV with conduction deficits post-TAVR. Our results demonstrate an association of ECV, and thereby interstitial myocardial fibrosis, with new conduction derangement post-TAVR and introduce ECV as a potentially new risk stratifica","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141476024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remote proctoring during structural heart procedures: Toward a widespread diffusion of knowledge using mixed reality. 结构性心脏手术过程中的远程监考:利用混合现实技术广泛传播知识。
IF 2.1 3区 医学
Catheterization and Cardiovascular Interventions Pub Date : 2024-11-01 Epub Date: 2024-08-17 DOI: 10.1002/ccd.31187
Guido Ascione, Giovanni Rossini, Davide Schiavi, Nicolò Azzola Guicciardi, Matteo Saccocci, Nicola Buzzatti, Cosmo Godino, Ottavio Alfieri, Eustachio Agricola, Francesco Maisano, Paolo Denti
{"title":"Remote proctoring during structural heart procedures: Toward a widespread diffusion of knowledge using mixed reality.","authors":"Guido Ascione, Giovanni Rossini, Davide Schiavi, Nicolò Azzola Guicciardi, Matteo Saccocci, Nicola Buzzatti, Cosmo Godino, Ottavio Alfieri, Eustachio Agricola, Francesco Maisano, Paolo Denti","doi":"10.1002/ccd.31187","DOIUrl":"10.1002/ccd.31187","url":null,"abstract":"<p><strong>Background: </strong>Despite its wide diffusion in surgical procedures, very few experiences are reported so far about the possible applications of remote proctoring (RP) in structural heart interventions.</p><p><strong>Aims: </strong>Our aim was to demonstrate the feasibility, safety, and efficacy of RP during transcatheter edge-to-edge repair using a mixed reality-based head-mounted display (HMD).</p><p><strong>Methods: </strong>Two users (a doctor and a proctor), wearing HMDs, were connected through a 5G network, allowing them to share audio and video signals. During the procedure, the proctor was located in a contiguous room, without any direct connection with the operator. The primary endpoint was noninferiority of HMD-mediated interaction if compared with direct in-person interaction. It was assessed using an operator-proctor interaction test based on six questions asked by the doctor to the proctor on six key procedural steps.</p><p><strong>Results: </strong>Between September 2021 and April 2022, nine patients were enrolled in the study (15 clips delivered). The primary endpoint was reached in 9/15 clips implanted (60%). The first three failures were due to a chat software problem, and the others were linked with a 5G network malfunction. However, the HMD and its mixed reality tools were well tolerated by the operators, and no interference with the procedure was registered in any of the cases.</p><p><strong>Conclusions: </strong>In our experience, RP during structural heart interventions is feasible and efficacious. Wearing the HMD is comfortable and does not affect safety and effectiveness of interventional procedures. However, especially if considering a wide geographic use of this tool, a stable internet connection is imperative.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141995410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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